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Topic:Public Health

The topic of Public Health and horses encompasses the study of interactions between equine populations and human health systems. It involves examining the transmission of zoonotic diseases, which are diseases that can be transferred between animals and humans, as well as the role of horses in the epidemiology of such diseases. This field also considers the impact of equine-related activities on public health, including injuries and environmental effects. Research in this area often explores preventive measures, management strategies, and policies to mitigate health risks associated with horses. This page compiles peer-reviewed research studies and scholarly articles that investigate the intersection of equine and public health, focusing on disease transmission, risk assessment, and health management strategies.
Trypanosoma evansi and surra: a review and perspectives on origin, history, distribution, taxonomy, morphology, hosts, and pathogenic effects.
BioMed research international    August 19, 2013   Volume 2013 194176 doi: 10.1155/2013/194176
Desquesnes M, Holzmuller P, Lai DH, Dargantes A, Lun ZR, Jittaplapong S.Trypanosoma evansi, the agent of "surra," is a salivarian trypanosome, originating from Africa. It is thought to derive from Trypanosoma brucei by deletion of the maxicircle kinetoplastic DNA (genetic material required for cyclical development in tsetse flies). It is mostly mechanically transmitted by tabanids and stomoxes, initially to camels, in sub-Saharan area. The disease spread from North Africa towards the Middle East, Turkey, India, up to 53° North in Russia, across all South-East Asia, down to Indonesia and the Philippines, and it was also introduced by the conquistadores into Latin ...
The antimicrobial activity of honey against common equine wound bacterial isolates.
Veterinary journal (London, England : 1997)    August 17, 2013   Volume 199, Issue 1 110-114 doi: 10.1016/j.tvjl.2013.07.003
Carnwath R, Graham EM, Reynolds K, Pollock PJ.Delayed healing associated with distal limb wounds is a particular problem in equine clinical practice. Recent studies in human beings and other species have demonstrated the beneficial wound healing properties of honey, and medical grade honey dressings are available commercially in equine practice. Equine clinicians are reported to source other non-medical grade honeys for the same purpose. This study aimed to assess the antimicrobial activity of a number of honey types against common equine wound bacterial pathogens. Twenty-nine honey products were sourced, including gamma-irradiated and no...
Sparse evidence for equine or avian influenza virus infections among Mongolian adults with animal exposures.
Influenza and other respiratory viruses    August 13, 2013   Volume 7, Issue 6 1246-1250 doi: 10.1111/irv.12148
Khurelbaatar N, Krueger WS, Heil GL, Darmaa B, Ulziimaa D, Tserennorov D, Baterdene A, Anderson BD, Gray GC.In recent years, Mongolia has experienced recurrent epizootics of equine influenza virus (EIV) among its 2·1 million horses and multiple incursions of highly pathogenic avian influenza (HPAI) virus via migrating birds. No human EIV or HPAI infections have been reported. In 2009, 439 adults in Mongolia were enrolled in a population-based study of zoonotic influenza transmission. Enrollment sera were examined for serological evidence of infection with nine avian, three human, and one equine influenza virus strains. Seroreactivity was sparse among participants suggesting little human risk of zoo...
The changing face of the henipaviruses.
Veterinary microbiology    August 13, 2013   Volume 167, Issue 1-2 151-158 doi: 10.1016/j.vetmic.2013.08.002
Croser EL, Marsh GA.The Henipavirus genus represents a group of paramyxoviruses that are some of the deadliest of known human and veterinary pathogens. Hendra and Nipah viruses are zoonotic pathogens that can cause respiratory and encephalitic illness in humans with mortality rates that exceed 70%. Over the past several years, we have seen an increase in the number of cases and an altered clinical presentation of Hendra virus in naturally infected horses. Recent increase in the number of cases has also been reported with human Nipah virus infections in Bangladesh. These factors, along with the recent discovery of...
Evidence for the circulation of equine encephalosis virus in Israel since 2001.
PloS one    August 12, 2013   Volume 8, Issue 8 e70532 doi: 10.1371/journal.pone.0070532
Westcott D, Wescott DG, Mildenberg Z, Bellaiche M, McGowan SL, Grierson SS, Choudhury B, Steinbach F.Equine encephalosis virus (EEV) distribution was thought to be limited to southern Africa until 2008 when we reported EEV in Israel. It was then assumed that the clinical presentation resembled the initial incursion in Israel. To investigate further we conducted a retrospective analysis of equine sera, which had been collected for diagnosis of other suspected diseases, via serum neutralisation test. The data demonstrated that EEV was circulating as early as 2001 with incidence ranging from 20-100% for time period 2001-2008. As the symptoms of EEV can be similar to other equine notifiable disea...
Identification of a human monoclonal antibody to replace equine diphtheria antitoxin for treatment of diphtheria intoxication.
Infection and immunity    August 12, 2013   Volume 81, Issue 11 3992-4000 doi: 10.1128/IAI.00462-13
Sevigny LM, Booth BJ, Rowley KJ, Leav BA, Cheslock PS, Garrity KA, Sloan SE, Thomas W, Babcock GJ, Wang Y.Diphtheria antitoxin (DAT) has been the cornerstone of the treatment of Corynebacterium diphtheriae infection for more than 100 years. Although the global incidence of diphtheria has declined steadily over the last quarter of the 20th century, the disease remains endemic in many parts of the world, and significant outbreaks still occur. DAT is an equine polyclonal antibody that is not commercially available in the United States and is in short supply globally. A safer, more readily available alternative to DAT would be desirable. In the current study, we obtained human monoclonal antibodies (h...
West Nile Virus equine serosurvey in the Czech and Slovak republics.
Vector borne and zoonotic diseases (Larchmont, N.Y.)    August 6, 2013   Volume 13, Issue 10 733-738 doi: 10.1089/vbz.2012.1159
Hubálek Z, Ludvíková E, Jahn P, Treml F, Rudolf I, Svobodová P, Šikutová S, Betášová L, Bíreš J, Mojžíš M, Tinák M, Boldižár M....A serological survey for West Nile virus (WNV) infection involved 395 horses from 43 administrative districts of the Czech Republic (163 animals) and 29 districts of Slovakia (232 animals), sampled between 2008 and 2011. Using a plaque-reduction neutralization microtest, antibodies to WNV were not detected in any horse from the Czech Republic, whereas 19 nonvaccinated horses from Slovakia had specific antibodies to WNV (no cross-reactions were observed with tick-borne encephalitis and Usutu flaviviruses in those animals). The seropositivity rate of nonvaccinated horses in Slovakia was 8.3% (95...
Veterinary dentistry: a clinician’s viewpoint.
Dental update    August 6, 2013   Volume 40, Issue 5 386-390 doi: 10.12968/denu.2013.40.5.386
Baxter C.This is a clinician's view of the current state of veterinary dentistry at the level of the general practitioner across the different species. An indication of the work done and the hazards commonly encountered are covered. Conclusions: To increase awareness within the dental profession of the current state of veterinary dentistry.
A clinician’s guide to factors affecting withdrawal times for equine therapeutic medications.
Veterinary journal (London, England : 1997)    August 6, 2013   Volume 198, Issue 2 313-321 doi: 10.1016/j.tvjl.2013.07.002
Tobin T, Dirikolu L, Brewer K, Hughes CG.Equine forensic science can now detect concentrations down to 25 femtograms/mL (parts per quadrillion, ppq) or less in blood and urine. As such, horsemen are increasingly at risk of inadvertent 'positives' due to therapeutic medication 'overages' or trace identifications of dietary or environmental substances. Reviewed here are the factors which determine detection times and 'withdrawal times' for substances administered to horses. Withdrawal times are affected by many factors, including dose, formulation, route and frequency of administration, bioavailability, plasma half-life, sensitivity of...
Eastern equine encephalitis virus: high seroprevalence in horses from Southern Quebec, Canada, 2012.
Vector borne and zoonotic diseases (Larchmont, N.Y.)    August 6, 2013   Volume 13, Issue 10 712-718 doi: 10.1089/vbz.2012.1242
Rocheleau JP, Arsenault J, Lindsay LR, DiBernardo A, Kulkarni MA, Côté N, Michel P.Eastern equine encephalitis virus (EEEV) is a highly pathogenic arbovirus that infects humans, horses, and other animals. There has been a significant increase in EEEV activity in southeastern Canada since 2008. Few data are available regarding nonlethal EEEV infections in mammals, and consequently the distribution and pathogenicity spectrum of EEEV infections in these hosts is poorly understood. This cross-sectional study focuses on the evaluation of viral activity in southern Quebec's horses by seroprevalence estimation. A total of 196 horses, 18 months and older, which had never been vaccin...
What can mathematical models bring to the control of equine influenza?
Equine veterinary journal    August 2, 2013   Volume 45, Issue 6 784-788 doi: 10.1111/evj.12104
Daly JM, Newton JR, Wood JL, Park AW.Mathematical modelling of infectious disease is increasingly regarded as an important tool in the development of disease prevention and control measures. This article brings together key findings from various modelling studies conducted over the past 10 years that are of relevance to those on the front line of the battle against equine influenza.
How humans handle the Hendra virus risk.
Australian veterinary journal    July 31, 2013   Volume 91, Issue 8 N2 doi: 10.1111/j.1751-0813.2013.000105.GRP.x
Richmond R.No abstract available
Testing for Hendra virus: difficulties experienced by veterinarians in Queensland prior to 2011.
Australian veterinary journal    July 31, 2013   Volume 91, Issue 8 323-327 doi: 10.1111/avj.12091
Mendez D, Judd J, Speare R.To identify the perceived barriers to Hendra virus (HeV) management by private equine veterinarians in Queensland. Methods: An exploratory qualitative study of private equine veterinarians registered and working in coastal Queensland. Methods: A questionnaire that included eight open-ended questions about the management of HeV was used in face-to-face in-depth interviews with 21 veterinary personnel working in equine or mixed private practice between Far North and South-East Queensland in 2009-10. The qualitative data was entered and analysed thematically using QSR's International's Nvivo 9 qu...
Perceptions of vulnerability to a future outbreak: a study of horse managers affected by the first Australian equine influenza outbreak.
BMC veterinary research    July 31, 2013   Volume 9 152 doi: 10.1186/1746-6148-9-152
Schemann K, Firestone SM, Taylor MR, Toribio JA, Ward MP, Dhand NK.A growing body of work shows the benefits of applying social cognitive behavioural theory to investigate infection control and biosecurity practices. Protection motivation theory has been used to predict protective health behaviours. The theory outlines that a perception of a lack of vulnerability to a disease contributes to a reduced threat appraisal, which results in poorer motivation, and is linked to poorer compliance with advised health protective behaviours. This study, conducted following the first-ever outbreak of equine influenza in Australia in 2007, identified factors associated wit...
Response of Australian veterinarians to the announcement of a Hendra virus vaccine becoming available.
Australian veterinary journal    July 31, 2013   Volume 91, Issue 8 328-331 doi: 10.1111/avj.12092
Mendez D, Büttner P, Speare R.A cross-sectional study of private veterinarians providing equine services in Queensland. Results: The study revealed that a majority of veterinarians would support the introduction of a Hendra virus (HeV) vaccine. Moreover, almost half of the respondents intended to make vaccination a prerequisite to horse patient presentation. However, participants also responded that a vaccine would not reduce the risk sufficiently to cease or downgrade their HeV management plan and infection control measures. Conclusions: When devising promoting and marketing campaigns, government agencies and manufacturer...
Vesicular stomatitis outbreak in the southwestern United States, 2012. McCluskey BJ, Pelzel-McCluskey AM, Creekmore L, Schiltz J.Vesicular stomatitis is a viral disease primarily affecting horses and cattle when it occurs in the United States. Outbreaks in the southwestern United States occur sporadically, with initial cases typically occurring in Texas, New Mexico, or Arizona and subsequent cases occurring in a northward progression. The viruses causing vesicular stomatitis can be transmitted by direct contact of lesioned animals with other susceptible animals, but transmission is primarily through arthropod vectors. In 2012, an outbreak of vesicular stomatitis in the United States occurred that was caused by Vesicular...
Use of competition ELISA for monitoring of West Nile virus infections in horses in Germany.
International journal of environmental research and public health    July 24, 2013   Volume 10, Issue 8 3112-3120 doi: 10.3390/ijerph10083112
Ziegler U, Angenvoort J, Klaus C, Nagel-Kohl U, Sauerwald C, Thalheim S, Horner S, Braun B, Kenklies S, Tyczka J, Keller M, Groschup MH.West Nile virus (WNV) is a mosquito-borne viral pathogen of global importance and is considered to be the most widespread flavivirus in the World. Horses, as dead-end hosts, can be infected by bridge mosquito vectors and undergo either subclinical infections or develop severe neurological diseases. The aim of this study was to detect WNV specific antibodies in horses in Germany as an indicator for an endemic circulation of WNV. Sera from more than 5,000 horses (primarily fallen stock animals) were collected in eight different federal states of Germany from 2010 to 2012. Sera were screened by a...
Identification of hotspots in the European union for the introduction of four zoonotic arboviroses by live animal trade.
PloS one    July 23, 2013   Volume 8, Issue 7 e70000 doi: 10.1371/journal.pone.0070000
Durand B, Lecollinet S, Beck C, Martínez-López B, Balenghien T, Chevalier V.Live animal trade is considered a major mode of introduction of viruses from enzootic foci into disease-free areas. Due to societal and behavioural changes, some wild animal species may nowadays be considered as pet species. The species diversity of animals involved in international trade is thus increasing. This could benefit pathogens that have a broad host range such as arboviruses. The objective of this study was to analyze the risk posed by live animal imports for the introduction, in the European Union (EU), of four arboviruses that affect human and horses: Eastern and Western equine enc...
Pathogenesis of Venezuelan equine encephalitis.
Veterinary microbiology    July 22, 2013   Volume 167, Issue 1-2 145-150 doi: 10.1016/j.vetmic.2013.07.012
Taylor KG, Paessler S.Equine encephalids have high mortality rates and represent a significant zoonotic public health threat. Of these the most pathogenic viruses to equids are the alphaviruses in the family Togaviridae. The focus of this review Venezualen equine encephalitis virus (VEEV) has caused the most widespread and recent epidemic outbreaks of disease. Circulation in naturally occuring rodent-mosquito cycles, results in viral spread to both human and equine populations. However, equines develop a high titer viremia and can transmit the virus back to mosquito populations. As such, the early recognition and c...
Equine disease surveillance: quarterly summary.
The Veterinary record    July 9, 2013   Volume 173, Issue 1 11-13 doi: 10.1136/vr.f4254
No abstract available
Focus on: African horse sickness.
The Veterinary record    July 9, 2013   Volume 173, Issue 1 13-14 doi: 10.1136/vr.f4250
Hopley R, Toth B.No abstract available
Identification of novel immunoreactive proteins of Streptococcus zooepidemicus with potential as vaccine components.
Vaccine    July 8, 2013   Volume 31, Issue 38 4129-4135 doi: 10.1016/j.vaccine.2013.06.100
Velineni S, Timoney JF.Streptococcus zooepidemicus is an important opportunistic pathogen of the equine respiratory and reproductive tracts. A normal tonsillar and mucosal commensal, it becomes invasive under conditions of stress such as virus infection, weaning, high temperature, prolonged transportation and failure of uterine involution. The aim of this study was to evaluate the vaccine potential of several surface exposed and secreted proteins of a novel mucoid clone of SzNC78 (ST-307) from an epizootic of equine respiratory disease. Methods: An expression gene library of SzNC78 was probed with a pool of convales...
Surveillance of equine influenza viruses through the RESPE network in France from November 2005 to October 2010.
Equine veterinary journal    July 8, 2013   Volume 45, Issue 6 776-783 doi: 10.1111/evj.12100
Legrand LJ, Pitel PH, Marcillaud-Pitel CJ, Cullinane AA, Couroucé AM, Fortier GD, Freymuth FL, Pronost SL.The Réseau d'Epidémio-Surveillance en Pathologie Equine (RESPE, the French epidemiological network for equine diseases) is a network for epidemio-surveillance of major equine diseases based around sentry veterinarians in France. Objective: The aim of this study was to evaluate the contribution of RESPE to efficient surveillance of equine influenza virus (EIV) in France. Methods: Retrospective cross-sectional study. Methods: From November 2005 to October 2010, epidemiological and phylogenetic studies were performed on 1426 nasopharyngeal swabs received at the Frank Duncombe Laboratory. Detect...
Equine herpesviruses type 1 (EHV-1) and 4 (EHV-4)–masters of co-evolution and a constant threat to equids and beyond.
Veterinary microbiology    July 6, 2013   Volume 167, Issue 1-2 123-134 doi: 10.1016/j.vetmic.2013.06.018
Ma G, Azab W, Osterrieder N.The equine herpesviruses type 1 (EHV-1) and 4 (EHV-4) are ubiquitous pathogens that affect horse populations on all continents. Despite widespread vaccination, EHV-1 and EHV-4 infections remain a permanent risk. While the two viruses share a high degree of genetic and antigenic similarity, they differ significantly in host range and pathogenicity. Compared to EHV-4, which mainly infects horses and causes respiratory disease, EHV-1 has a broader host range and can result in respiratory disease, abortions, neonatal death, and equine herpesvirusmyeloencephalopathy (EHM). Recent studies have eluci...
A treatment for and vaccine against the deadly Hendra and Nipah viruses.
Antiviral research    July 6, 2013   Volume 100, Issue 1 8-13 doi: 10.1016/j.antiviral.2013.06.012
Broder CC, Xu K, Nikolov DB, Zhu Z, Dimitrov DS, Middleton D, Pallister J, Geisbert TW, Bossart KN, Wang LF.Hendra virus and Nipah virus are bat-borne paramyxoviruses that are the prototypic members of the genus Henipavirus. The henipaviruses emerged in the 1990s, spilling over from their natural bat hosts and causing serious disease outbreaks in humans and livestock. Hendra virus emerged in Australia and since 1994 there have been 7 human infections with 4 case fatalities. Nipah virus first appeared in Malaysia and subsequent outbreaks have occurred in Bangladesh and India. In total, there have been an estimated 582 human cases of Nipah virus and of these, 54% were fatal. Their broad species tropis...
Crisis communication. Horse industry working on better response to disease outbreaks.
Journal of the American Veterinary Medical Association    July 5, 2013   Volume 242, Issue 11 1461-1462 
Larkin M.No abstract available
Rhodococcus equi: the many facets of a pathogenic actinomycete.
Veterinary microbiology    July 5, 2013   Volume 167, Issue 1-2 9-33 doi: 10.1016/j.vetmic.2013.06.016
Vázquez-Boland JA, Giguère S, Hapeshi A, MacArthur I, Anastasi E, Valero-Rello A.Rhodococcus equi is a soil-dwelling pathogenic actinomycete that causes pulmonary and extrapulmonary pyogranulomatous infections in a variety of animal species and people. Young foals are particularly susceptible and develop a life-threatening pneumonic disease that is endemic at many horse-breeding farms worldwide. R. equi is a facultative intracellular parasite of macrophages that replicates within a modified phagocytic vacuole. Its pathogenicity depends on a virulence plasmid that promotes intracellular survival by preventing phagosome-lysosome fusion. Species-specific tropism of R. equi fo...
Demonstration of Usutu virus antibodies in horses, Croatia.
Vector borne and zoonotic diseases (Larchmont, N.Y.)    June 29, 2013   Volume 13, Issue 10 772-774 doi: 10.1089/vbz.2012.1236
Barbic L, Vilibic-Cavlek T, Listes E, Stevanovic V, Gjenero-Margan I, Ljubin-Sternak S, Pem-Novosel I, Listes I, Mlinaric-Galinovic G, Di Gennaro A....We report the first serological evidence of Usutu virus (USUV) infection in horses in Croatia. During 2011, 1380 horse serum samples from healthy animals were collected from six northern Croatian counties. All samples were first screened for West Nile virus (WNV) immunoglobulin G (IgG) antibodies using an enzyme-linked immunosorbent assay (ELISA). Sixty-nine WNV ELISA-reactive samples were further tested for WNV antibodies by a virus neutralization assay (VN assay) and plaque reduction neutralization test (PRNT), and USUV by a VN assay and tick-borne encephalitis virus (TBEV) antibodies by PRN...
Northern Ireland disease surveillance, January to March 2013.
The Veterinary record    June 26, 2013   Volume 172, Issue 25 657-658 doi: 10.1136/vr.f3577
No abstract available
Princess Royal draws attention to growing horse crisis.
The Veterinary record    June 26, 2013   Volume 172, Issue 25 649 doi: 10.1136/vr.f3918
No abstract available
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