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Topic:Retrospective Study

Retrospective studies in horses involve the analysis of pre-existing data to identify patterns, outcomes, and associations related to health and disease within equine populations. These studies utilize historical records, such as veterinary medical histories, treatment outcomes, and diagnostic results, to explore various aspects of equine health and management. Retrospective studies can provide insights into the prevalence of diseases, the effectiveness of treatments, and risk factors associated with certain conditions. This page aggregates peer-reviewed research studies and scholarly articles that focus on the methodologies, findings, and implications of retrospective analyses in equine veterinary science.
Adverse reactions in horses that underwent general anesthesia and cervical myelography.
Journal of veterinary internal medicine    April 9, 2015   Volume 29, Issue 3 954-960 doi: 10.1111/jvim.12590
Mullen KR, Furness MC, Johnson AL, Norman TE, Hart KA, Burton AJ, Bicahlo RC, Ainsworth DM, Thompson MS, Scrivani PV.The study was prompted by a perceived high prevalence of myelographic complications varying in severity and type, and attributed to the contrast material or the procedure. Objective: 1. Any adverse reaction (AAR) is associated with a change in CSF volume induced either by removal of CSF or addition of contrast material. 2. AAR occurs more frequently in horses with higher premyelography neurologic grade. 3. Nonspecific hyperthermia is attenuated by anti-inflammatory and osmotic agents. Methods: Horses (n = 278) that underwent myelography between 2000 and 2012 at 5 institutions: A (87), B (68), ...
Risk factors for epistaxis in jump racing in Great Britain (2001-2009).
Veterinary journal (London, England : 1997)    April 9, 2015   Volume 205, Issue 1 44-49 doi: 10.1016/j.tvjl.2015.04.003
Reardon RJ, Boden LA, Mellor DJ, Love S, Newton RJ, Stirk AJ, Parkin TD.The aim of this study was to evaluate risk factors associated with developing epistaxis in jump racing in Great Britain (GB). A retrospective analysis of records from horses running in all hurdle and steeplechase races in GB between 2001 and 2009 identified diagnoses of epistaxis whilst still at the racecourse. Data were used from 603 starts resulting in epistaxis (event) and 169,065 starts resulting in no epistaxis (non-event) in hurdle racing, and from 550 event starts and 102,344 non-event starts in steeplechase racing. Two multivariable logistic regression models to evaluate risk factors a...
Clinical treatment and prognosis of equine odontoclastic tooth resorption and hypercementosis.
Equine veterinary journal    April 3, 2015   Volume 48, Issue 2 188-194 doi: 10.1111/evj.12406
Lorello O, Foster DL, Levine DG, Boyle A, Engiles J, Orsini JA.Equine odontoclastic tooth resorption and hypercementosis is an infrequent and underdiagnosed form of severe dental disease in horses that can affect quality of life. The study was performed to compare the clinical, radiographic, histological and prognostic findings specific to equine odontoclastic tooth resorption and hypercementosis in horses. Removal of affected teeth is currently the best treatment. Objective: The goals are to report salient clinical and histological features of the disease and its management in a case series describing an under-reported syndrome in horses and the long-ter...
Serum bile acid concentrations, histopathological features, and short-, and long-term survival in horses with hepatic disease.
Journal of veterinary internal medicine    March 31, 2015   Volume 29, Issue 2 644-650 doi: 10.1111/jvim.12551
Dunkel B, Jones SA, Pinilla MJ, Foote AK.Serum bile acid concentrations (SBA) and a histopathological biopsy score [Equine Vet J 35 (2003) 534] are used prognostically in equine hepatic disease. Objective: Histopathologic features and scores, but not SBA, differ between survivors and nonsurvivors and correlate with histopathologic evidence of hepatic inflammation and fibrosis. Methods: Retrospective study. Records (1999-2011) of horses with hepatic disease diagnosed by biopsy and with concurrent measurements of SBA. Methods: Retrospective cohort study. Biopsies were examined for inflammatory cell infiltration including type and distr...
Cryptorchidectomy in equids: 604 cases (1977-2010).
Journal of the American Veterinary Medical Association    March 21, 2015   Volume 246, Issue 7 777-784 doi: 10.2460/javma.246.7.777
Hartman R, Hawkins JF, Adams SB, Moore GE, Fessler JF.To evaluate the management of equids undergoing cryptorchidectomy at a referral hospital. Methods: Retrospective case series. Methods: 604 client-owned equids. Methods: Medical records of all equids undergoing surgical treatment of cryptorchidism from 1977 to 2010 were retrospectively reviewed. Analyses of breed, location of retained testes, accuracy of palpation per rectum for determining the location of retained testes, surgical technique, and postoperative complications were performed. Results: The most frequently affected breed was the Quarter Horse (282/604 [47%]), which was significantly...
Bacterial isolates, antimicrobial susceptibility patterns, and factors associated with infection and outcome in foals with septic arthritis: 83 cases (1998-2013).
Journal of the American Veterinary Medical Association    March 21, 2015   Volume 246, Issue 7 785-793 doi: 10.2460/javma.246.7.785
Hepworth-Warren KL, Wong DM, Fulkerson CV, Wang C, Sun Y.To determine clinical characteristics, clinicopathologic data, and bacterial culture and antimicrobial susceptibility results associated with septic arthritis in foals ≤ 180 days old. Methods: Retrospective case series. Methods: 83 foals with septic arthritis. Methods: Medical records at 2 teaching hospitals between 1998 and 2013 were searched to identify those for foals ≤ 180 days old with confirmed infection of ≥ 1 synovial structure. Data extracted from the records included signalment, clinicopathologic information, bacteriologic culture and antimicrobial susceptibility results, and o...
Serum amyloid A, haptoglobin, and ferritin in horses with colic: Association with common clinicopathological variables and short-term outcome.
Veterinary journal (London, England : 1997)    March 19, 2015   Volume 205, Issue 1 50-55 doi: 10.1016/j.tvjl.2015.03.015
Dondi F, Lukacs RM, Gentilini F, Rinnovati R, Spadari A, Romagnoli N.Equine colic may be associated with an acute phase response (APR). Measurement of acute phase proteins (APPs) allows the detection of an APR and may help clinicians in monitoring the disease; however, the role of APPs in colic is unclear. This study aimed to evaluate the clinical usefulness of serum amyloid A (SAA), haptoglobin and ferritin in combination with an extended clinicopathological profile in equine colic. The medical records of 54 horses were retrospectively selected. Horses were grouped based on outcome (survivors vs. non-survivors), diagnosis (ischaemic/strangulating vs. non-ischa...
Nonstrangulating intestinal infarction associated with Strongylus vulgaris in referred Danish equine cases.
Equine veterinary journal    March 12, 2015   Volume 48, Issue 3 376-379 doi: 10.1111/evj.12422
Nielsen MK, Jacobsen S, Olsen SN, Bousquet E, Pihl T.Strongylus vulgaris is a pathogenic helminth parasite infecting horses and was once considered to be the primary cause of colic. Migrating larvae cause ischaemia and infarction of intestinal segments. This knowledge is derived from case reports and experimental inoculations of parasite-naïve foals, and it remains unknown to what extent the parasite is associated with different types of colic. Objective: To evaluate the role of S. vulgaris as a risk factor for different types of colic in horses. Methods: A retrospective case-control study among horses referred with abdominal pain to the Univ...
Navigational ultrasound imaging: A novel imaging tool for aiding interventional therapies of equine musculoskeletal injuries.
Equine veterinary journal    March 12, 2015   Volume 48, Issue 2 195-200 doi: 10.1111/evj.12410
Lustgarten M, Redding WR, Schnabel LV, Prange T, Seiler GS.Navigational ultrasound imaging, also known as fusion imaging, is a novel technology that allows real-time ultrasound imaging to be correlated with a previously acquired computed tomography (CT) or magnetic resonance imaging (MRI) study. It has been used in man to aid interventional therapies and has been shown to be valuable for sampling and assessing lesions diagnosed with MRI or CT that are equivocal on ultrasonography. To date, there are no reports of the use of this modality in veterinary medicine. Objective: To assess whether navigational ultrasound imaging can be used to assist commonly...
Quantitative motor unit action potential analysis of supraspinatus, infraspinatus, deltoideus and biceps femoris muscles in adult Royal Dutch sport horses.
Equine veterinary journal    March 4, 2015   Volume 48, Issue 2 234-239 doi: 10.1111/evj.12419
Jose-Cunilleras E, Wijnberg ID.Reference values for quantitative electromyography (QEMG) in shoulder and hindlimb muscles of horses are limited. Objective: To determine normative data on QEMG analysis of supraspinatus (SS), infraspinatus (IS), deltoideus (DT) and biceps femoris (BF) muscles. Methods: Experimental observational study and retrospective case series. Methods: Seven adult healthy Royal Dutch sport horses underwent quantitative motor unit action potential analysis of each muscle using commercial electromyography equipment. Measurements were made according to published methods. One-way ANOVA was used to compare qu...
Correlation of radiographic measurements of structures of the equine foot with lesions detected on magnetic resonance imaging.
Equine veterinary journal    March 4, 2015   Volume 48, Issue 2 165-171 doi: 10.1111/evj.12411
de Zani D, Polidori C, di Giancamillo M, Zani DD.There are few studies on the correlations between radiographic measurements of the foot and abnormalities of specific structures found with magnetic resonance imaging (MRI). Objective: To document the relationship between radiographic measurements of the equine foot and the presence of lesions in the foot on MRI. We hypothesised that different radiographic measurements would be associated with specific lesions detected by MRI. Methods: Retrospective analysis of radiographs and MRI studies. Methods: Seventy-four feet from 52 lame horses were included. Twenty parameters were measured on radiogra...
Mare and foal survival and subsequent fertility of mares treated for uterine torsion.
Equine veterinary journal    March 4, 2015   Volume 48, Issue 2 172-175 doi: 10.1111/evj.12418
Spoormakers TJ, Graat EA, ter Braake F, Stout TA, Bergman HJ.Previous surveys have reported that mare and foal survival after correction of uterine torsion (UT) varies from 60 to 84% and from 30 to 54%, respectively. Furthermore, resolution via a standing flank laparotomy (SFL) has been associated with better foal, but not mare, survival. Objective: To compare the success of SFL with other correction methods (e.g. midline or flank laparotomy under general anaesthesia; correction per vaginam). Methods: Retrospective analysis of clinical records. Methods: Data on correction technique, stage of gestation, degree of rotation, survival and subsequent fertili...
Prospective, retrospective or clinical audit: A label that sticks.
Equine veterinary journal    February 25, 2015   Volume 47, Issue 3 257-259 doi: 10.1111/evj.12409
Wylie CE.No abstract available
Outcome of medial patellar ligament desmoplasty for treatment of intermittent upward fixation of the patella in 24 horses (2005-2012).
The Canadian veterinary journal = La revue veterinaire canadienne    February 20, 2015   Volume 56, Issue 2 193-195 
Peitzmeier MD, Koontz ZD, Lynch TM, Hughes FE, Slone DE.This retrospective study provides long-term results of medial patellar ligament (MPL) desmoplasty in horses with intermittent upward fixation of the patella (UFP) that were treated at a single referral hospital over a 7-year period. Follow-up interviews were conducted with owners, trainers, or referring veterinarians using a standardized questionnaire. Overall, 71% of horses returned to their intended use with only 18% at a higher level. Recurrence of UFP was noted in 33% of cases. Satisfaction with the procedure was generally low, with only 50% of owners being completely satisfied. Further in...
Racing performance following prosthetic laryngoplasty using a polyurethane prosthesis combined with a laser-assisted ventriculocordectomy for treatment of recurrent laryngeal neuropathy in 78 Thoroughbred racehorses.
Equine veterinary journal    February 14, 2015   Volume 47, Issue 1 60-64 doi: 10.1111/evj.12237
Raffetto JA, Wearn JG, Fischer AT.Recurrent laryngeal neuropathy (RLN) causes airway obstruction and adversely affects racing performance in Thoroughbred racehorses. Prosthetic laryngoplasty (PL) is the preferred treatment of RLN as it returns variables of airway mechanics to baseline. A number of materials have been evaluated as prostheses; however, the application of Lycra has not been rigorously investigated. Objective: To evaluate the efficacy of PL using a Lycra prosthesis, in combination with transendoscopic, laser-assisted ventriculocordectomy, to restore racing performance in Thoroughbred racehorses with RLN. Methods: ...
Indications, complications, and outcome of horses undergoing repeated celiotomy within 14 days after the first colic surgery: 95 cases (2005-2013).
Journal of the American Veterinary Medical Association    February 12, 2015   Volume 246, Issue 5 540-546 doi: 10.2460/javma.246.5.540
Dunkel B, Mair T, Marr CM, Carnwath J, Bolt DM.To examine factors associated with short- and long-term prognosis for horses undergoing repeated celiotomy within 14 days after the first colic surgery. Methods: Retrospective case series. Methods: 95 horses that had undergone 2 celiotomies within a 14-day period between 2005 and 2013 at 3 equine referral hospitals. Methods: Historical, clinical, and laboratory data were compared between horses that did not survive and horses that did survive to hospital discharge (short-term survival rate) and to > 3 and > 6 months after hospital discharge (long-term survival rates). Results: Strangulat...
Anatomical variation of the spinous and transverse processes in the caudal cervical vertebrae and the first thoracic vertebra in horses.
Equine veterinary journal    February 11, 2015   Volume 48, Issue 1 45-49 doi: 10.1111/evj.12397
Santinelli I, Beccati F, Arcelli R, Pepe M.There are scant data on the incidence of different anatomical variants of the equine caudal cervical spine, despite interest in cervical pathology. Objective: To identify morphological radiographic variation in the 6th and 7th cervical vertebrae and the first thoracic vertebra in horses of different breeds and to determine whether there are breed- and sex-related differences. Methods: Retrospective descriptive study. Methods: Radiographs of the cervical spine of 270 horses were assessed retrospectively. The Chi-square test, or Fisher's exact test when appropriate, was used to test for associat...
The role of catastrophic injury or sudden death of the horse in race-day jockey falls and injuries in California, 2007-2012.
Equine veterinary journal    February 2, 2015   Volume 48, Issue 1 50-56 doi: 10.1111/evj.12392
Hitchens PL, Hill AE, Stover SM.If equine conditions with high likelihood of jockey injury can be determined and subsequently prevented, jockey safety can be enhanced. Objective: To identify racehorse injuries or conditions with greatest risk for jockey falls and injuries. Methods: Retrospective correlation of race-day jockey fall and injury data with racehorse fatality data. Methods: Thoroughbred (TB) and Quarter Horse (QH) racehorse cause of death and jockey fall and injury data for California flat races were reviewed for a 6-year period. Race and jockey race ride population data were used to determine jockey fall and inju...
Season does not influence embryo recovery rate and conceptus size until day 14 after ovulation in the horse.
Reproduction in domestic animals = Zuchthygiene    January 27, 2015   Volume 50, Issue 2 299-303 doi: 10.1111/rda.12490
Aurich C, Budik S.Although the horse is a seasonal breeding species, a considerable number of mares continue to cycle throughout autumn and winter. Slower equine embryo growth during the non-breeding season has been hypothesized, and because smaller embryo size is beneficial for cryopreservation, embryo collection outside the breeding season could be an interesting approach for the production of frozen horse embryos. In the present retrospective study, we have therefore analysed embryo recovery rates and conceptus size in mares (n = 30) throughout the year. Conceptus diameter was either size determined after co...
Minimum inhibitory concentrations of equine Corynebacterium pseudotuberculosis isolates (1996-2012).
Journal of veterinary internal medicine    January 14, 2015   Volume 29, Issue 1 327-332 doi: 10.1111/jvim.12534
Rhodes DM, Magdesian KG, Byrne BA, Kass PH, Edman J, Spier SJ.Few studies report the minimum inhibitory concentrations for antimicrobials against equine Corynebacterium pseudotuberculosis isolates. Objective: To evaluate trends in the in vitro activities of 20 antimicrobials against equine Corynebacterium pseudotuberculosis isolates from 1996 to 2012 and to determine if a relationship exists between the minimum inhibitory concentration (MIC) and location of the abscess. Methods: Corynebacterium pseudotuberculosis isolates from 196 horses with naturally occurring disease. Methods: Retrospective and cross-sectional design. Medical records were reviewed to ...
Is there an association between clinical features, response to diagnostic analgesia and radiological findings in horses with a magnetic resonance imaging diagnosis of navicular disease or other injuries of the podotrochlear apparatus?
Veterinary journal (London, England : 1997)    January 8, 2015   Volume 204, Issue 1 40-46 doi: 10.1016/j.tvjl.2014.12.038
Parkes R, Newton R, Dyson S.Previous descriptions of the clinical features of navicular disease occurred before the widespread use of magnetic resonance imaging (MRI) allowed a more definitive diagnosis of foot pain. The objective of this study was to compare the clinical features of horses with lesions of the podotrochlear apparatus with those with other causes of foot pain. It was hypothesised that primary navicular bone disease would be associated with more advanced radiological findings than other diagnoses. A retrospective study was performed of all horses examined at a referral centre with a definitive diagnosis of...
Musculoskeletal lesions and lameness in 121 horses with carpal sheath effusion (1999-2010). Jorgensen JS, Genovese RL, Döpfer D, Stewart MC.Equine carpal sheath effusion has multiple etiologies. The purpose of this retrospective study was to describe the prevalence of distinct musculoskeletal lesions lameness in a sample of horses with a clinical diagnosis of carpal sheath effusion. A total of 121 horses met inclusion criteria. Seventy-four percent (89/121) of horses were lame at presentation; middle-aged (9-18 years, 80%) and older (> 18 years, 85%) horses were lame more frequently than young horses (< 9 years, 44%). Ninety-three percent (113/121) were diagnosed with osseous and/or soft tissue abnormalities. Of these 113 ho...
Risk factors associated with the transmission of Brazilian spotted fever in the Piracicaba river basin, State of São Paulo, Brazil.
Revista da Sociedade Brasileira de Medicina Tropical    January 1, 2015   Volume 48, Issue 1 11-17 doi: 10.1590/0037-8682-0281-2014
Souza CE, Pinter A, Donalisio MR.Brazilian spotted fever (BSF) is a disease transmitted by ticks for which the etiological agent is Rickettsia rickettsii. The present essay evaluates the risk factors associated with the transmission of cases of BSF in the time period between 2003 and 2013 in the Piracicaba river basin, state of São Paulo. Methods: This essay presents a retrospective study to identify the factors associated with the transmission of cases of BSF among all suspected cases identified by the System for Epidemiological Surveillance of São Paulo (CVE). After the description of temporal distribution (onset of sympt...
Quantitative molecular viral loads in 7 horses with naturally occurring equine herpesvirus-1 infection.
Equine veterinary journal    December 30, 2014   Volume 47, Issue 6 689-693 doi: 10.1111/evj.12351
Estell KE, Dawson DR, Magdesian KG, Swain E, Laing ST, Siso S, Mapes S, Pusterla N.Data associating quantitative viral load with severity, clinical signs and survival in equine herpesvirus-1 myeloencephalopathy (EHM) have not been reported. Objective: To report the clinical signs, treatment, and temporal progression of viral loads in 7 horses with naturally occurring EHM and to examine the association of these factors with survival. Methods: Retrospective case series. Methods: The population included 7 horses with EHM presented to the University of California, Davis William R. Pritchard Veterinary Medical Teaching Hospital from May to September 2011. Horses were graded using...
Equine pancreatic disease: a review and characterization of the lesions of four cases (2005-2014). Newman SJ.Equine pancreatic disease is considered rare, and successful treatment is limited. Additionally, antemortem diagnosis of equine pancreatitis is difficult because of the lack of definitive diagnostic tests. Although a paucity of information exists on this entity in the horse, pancreatic disease has typically been shown to be secondary to other gastrointestinal, hepatic, and endocrine conditions. No predisposition based on age, sex, or breed appears to exist, but several conditions predispose a horse to pancreatitis, including grain overload, endocrine disease, and parasite migration. A retrospe...
Duration of disease influences survival to discharge of Thoroughbred mares with surgically treated large colon volvulus.
Equine veterinary journal    December 14, 2014   Volume 47, Issue 6 650-654 doi: 10.1111/evj.12358
Hackett ES, Embertson RM, Hopper SA, Woodie JB, Ruggles AJ.Large colon volvulus results in strangulating obstruction requiring surgical treatment. Duration of this disease prior to surgical treatment is likely to influence survival directly. Objective: The primary objective of this study was to evaluate the influence of duration of large colon volvulus on patient survival to discharge. Relationships between other factors and survival following large colon volvulus were also examined. Methods: Retrospective case analysis. Methods: Medical records of Thoroughbred mares aged ≥2 years undergoing surgical treatment for large colon volvulus between 1 Marc...
Idiopathic focal eosinophilic enteritis (IFEE), an emerging cause of abdominal pain in horses: the effect of age, time and geographical location on risk.
PloS one    December 2, 2014   Volume 9, Issue 12 e112072 doi: 10.1371/journal.pone.0112072
Archer DC, Costain DA, Sherlock C.Idiopathic focal eosinophilic enteritis (IFEE) is an emerging cause of abdominal pain (colic) in horses that frequently requires surgical intervention to prevent death. The epidemiology of IFEE is poorly understood and it is difficult to diagnose pre-operatively. The aetiology of this condition and methods of possible prevention are currently unknown. The aims of this study were to investigate temporal and spatial heterogeneity in IFEE risk and to ascertain the effect of horse age on risk. Results: A retrospective, nested case-control study was undertaken using data from 85 IFEE cases and 848 ...
Porcine urinary bladder extracellular matrix grafts (ACell Vet® Corneal Discs) for keratomalacia in 17 equids (2012-2013).
Veterinary ophthalmology    November 27, 2014   Volume 19, Issue 1 3-10 doi: 10.1111/vop.12240
Mancuso LA, Lassaline M, Scherrer NM.To describe the clinical course, outcomes, and complications associated with use of commercially available porcine urinary bladder extracellular matrix (ECM) grafts (ACell Vet(®) Corneal Discs) in equid patients with keratomalacia, and to evaluate the efficacy of ECM grafts as a viable alternative to other biomaterials for corneal grafting in equid patients. Methods: Sixteen horses and one donkey (17 eyes) with unilateral keratomalacia severe enough to warrant surgical repair between August 2012 and September 2013. Methods: Retrospective medical record review to identify equid patients meetin...
Outcome of adult horses with botulism treated at a veterinary hospital: 92 cases (1989-2013).
Journal of veterinary internal medicine    November 19, 2014   Volume 29, Issue 1 311-319 doi: 10.1111/jvim.12502
Johnson AL, McAdams-Gallagher SC, Aceto H.There are no studies evaluating a large population of adult horses treated for botulism. Reported survival rates in outbreak situations are low; however, many horses in outbreaks do not receive treatment. Objective: That adult horses treated at a veterinary hospital would have improved survival compared to outbreak situations. Additional aims included identification of predictors of nonsurvival. Methods: All horses greater than 6 months of age with a final diagnosis of botulism admitted to a veterinary teaching hospital between 1989 and 2013 were included. Methods: Retrospective study. Histori...
Axial osteitis of the proximal sesamoid bones and desmitis of the intersesamoidean ligament in the hindlimb of Friesian horses: review of 12 cases (2002-2012) and post-mortem analysis of the bone-ligament interface.
BMC veterinary research    November 19, 2014   Volume 10 272 doi: 10.1186/s12917-014-0272-x
Brommer H, Voermans M, Veraa S, van den Belt AJ, van der Toorn A, Ploeg M, Gröne A, Back W.Axial osteitis of the proximal sesamoid bones and desmitis of the intersesamoidean ligament has been described in Friesian horses as well as in other breeds. The objectives of this study were to review the outcome of clinical cases of this disease in Friesian horses and analyse the pathology of the bone-ligament interface. Case records of Friesian horses diagnosed with axial osteitis of the proximal sesamoid bones and desmitis of the intersesamoidean ligament in the period 2002-2012 were retrospectively evaluated. Post-mortem examination was performed on horses that were euthanized (n = 3) and...
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