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Topic:Retrospective Study

Retrospective studies in horses involve the analysis of pre-existing data to identify patterns, outcomes, and associations related to health and disease within equine populations. These studies utilize historical records, such as veterinary medical histories, treatment outcomes, and diagnostic results, to explore various aspects of equine health and management. Retrospective studies can provide insights into the prevalence of diseases, the effectiveness of treatments, and risk factors associated with certain conditions. This page aggregates peer-reviewed research studies and scholarly articles that focus on the methodologies, findings, and implications of retrospective analyses in equine veterinary science.
Analysis of spatial and temporal clustering of horses with Salmonella krefeld in an intensive care unit of a veterinary hospital.
Journal of the American Veterinary Medical Association    August 1, 1996   Volume 209, Issue 3 626-628 
Paré J, Carpenter TE, Thurmond MC.To determine whether clustering existed in the spatial or temporal distribution of horses that shed Salmonella krefeld in their feces during hospitalization. Methods: Retrospective analysis of medical records. Methods: 219 horses housed in the intensive care unit of a veterinary medical teaching hospital from October 1991 through May 1992. Methods: Bacteriologic culturing of fecal samples was used to identify horses shedding S krefeld. For affected horses, the scan statistic was used to analyze temporal clustering, and Knox's method was used to analyze temporal-spatial clustering. Results: 20 ...
Case control and historical cohort study of diarrhea associated with administration of trimethoprim-potentiated sulphonamides to horses and ponies.
Journal of veterinary internal medicine    July 1, 1996   Volume 10, Issue 4 258-264 doi: 10.1111/j.1939-1676.1996.tb02059.x
Wilson DA, MacFadden KE, Green EM, Crabill M, Frankeny RL, Thorne JG.Trimethoprim-potentiated sulphonamides (TPS) are among the most frequently administered antimicrobials in equine medicine. Anecdotally, TPS has been implicated as a cause of mild to moderate diarrhea in horses. The purpose of this study was to document the prevalence of diarrhea in horses receiving TPS, to characterize the severity of the diarrhea, and to identify any other factors associated with the development of diarrhea. A 2-part study was designed to identify the prevalence of diarrhea associated with TPS in our clinic population. Part I was a case-control retrospective study of 135 reco...
Rectal biopsy diagnosis in horses with clinical signs of intestinal disorders: a retrospective study of 116 cases.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 275-284 doi: 10.1111/j.2042-3306.1996.tb03091.x
Lindberg R, Nygren A, Persson SG.The histology from rectal biopsy specimens taken 1980-1990 on 131 occasions from 116 horses, age 1-18 years, with clinical signs of intestinal disease was evaluated and classified retrospectively. In 40 horses, autopsy results were studied for comparison. Biopsy specimens (21 horses) and post mortem rectal tissue (9 horses) from 30 healthy horses, age 4-22 years, were used as controls. In 105 clinical cases, a biopsy was performed on only one occasion, while repeat biopsy was performed in 11 cases. Specimens showed pathological changes in 60 horses. The findings were classified into acute, chr...
Necrotizing enterocolitis in horses: a retrospective study.
Journal of veterinary internal medicine    July 1, 1996   Volume 10, Issue 4 265-270 doi: 10.1111/j.1939-1676.1996.tb02060.x
Saville WJ, Hinchcliff KW, Moore BR, Kohn CW, Reed SM, Mitten LA, Rivas LJ.The clinical and clinicopathologic characteristics of fatal necrotizing enterocolitis were examined in 16 horses (age 4 months to 12 years). At initial presentation, 8 of 16 horses were pyrexic (median temperature, 38.4 degrees C; range, 33.8 to 40.6 degrees C); all 16 were tachycardic (median heart rate, 93 bpm, range, 66 to 138 bpm); 13 of 16 were tachypneic (median heart rate, 36 bpm, range, 16 to 80 bpm), dehydrated, and had discolored mucous membranes. All horses that were pyrexic were also tachycardic and tachypneic. PCV was high (> 45%) in 14 horses. Six horses were leukopenic (< 5,000 ...
Rattlesnake venom poisoning in horses: 32 cases (1973-1993).
Journal of the American Veterinary Medical Association    June 1, 1996   Volume 208, Issue 11 1866-1871 
Dickinson CE, Traub-Dargatz JL, Dargatz DA, Bennett DG, Knight AP.To determine the clinical manifestations, morbidity, mortality, and treatment methods for rattlesnake venom poisoning in horses. Methods: Retrospective analysis of medical records. Methods: 27 horses with acute venom poisoning attributable to prairie rattlesnakes, and 5 with chronic problems subsequent to a rattlesnake bite. Results: Most horses were bitten on or near the muzzle while on pasture, resulting in head swelling, dyspnea, and epistaxis. Additional manifestations of acute poisoning included fever, tachycardia, tachypnea, cardiac arrhythmia, hemolytic anemia, thrombocytopenia, hemorrh...
Comparison of herniorrhaphy versus clamping of umbilical hernias in horses: a retrospective study of 93 cases (1982-1994).
The Canadian veterinary journal = La revue veterinaire canadienne    May 1, 1996   Volume 37, Issue 5 295-298 
Riley CB, Cruz AM, Bailey JV, Barber SM, Fretz PB.Many uncomplicated umbilical hernias have been managed successfully in foals by the application of a hernia clamp. Isolated reports of complications following clamp application have led some authors to suggest that it is an unsuitable method of treatment. Little information has been published comparing the complication rates associated with the use of hernia clamps and herniorrhaphy in the treatment of umbilical hernias. The purpose of this retrospective study was to report the characteristics of clinical cases of umbilical hernia and to compare the complication rates following these 2 treatme...
Metacarpophalangeal joint synovial pad fibrotic proliferation in 63 horses.
Veterinary surgery : VS    May 1, 1996   Volume 25, Issue 3 199-206 doi: 10.1111/j.1532-950x.1996.tb01399.x
Dabareiner RM, White NA, Sullins KE.Medical records, radiographs, and sonograms of 63 horses with metacarpophalangeal joint synovial pad proliferation were examined retrospectively. All horses had lameness, joint effusion, or both signs associated with one or both metacarpophalangeal joints. Bony remodeling and concavity of the distodorsal aspect of the third metacarpal bone (Mc3) just proximal to the metacarpal condyles was identified by radiography in 71 joints (93%); 24 joints (32%) had radiographic evidence of a chip fracture located at the proximal dorsal aspect of the proximal phalanx. Fifty-four joints (71%) were examined...
Infection of the intertubercular bursa in horses: four cases (1978-1991).
Journal of the American Veterinary Medical Association    May 1, 1996   Volume 208, Issue 9 1434-1437 
Vatistas NJ, Pascoe JR, Wright IM, Dyson SJ, Mayhew IG.To determine the clinical outcome of horses treated for infection of the intertubuercular bursa (infectious bicipital bursitis). Methods: Retrospective analysis of case records. Methods: Four horses referred for treatment of infectious bicipital bursitis. Methods: Medical records of horses that were severely lame on admission were reviewed. Results: In 3 horses, palpation over the bicipital bursa as well as flexion and extension of the scapulohumeral joint were resented. Ultrasonography performed in 1 horse revealed that the bicipital bursa was large and that excessive amounts of fluid contain...
Prognosis for return to racing after recovery from infectious pleuropneumonia in thoroughbred racehorses: 70 cases (1984-1989).
Journal of the American Veterinary Medical Association    April 15, 1996   Volume 208, Issue 8 1300-1301 
Seltzer KL, Byars TD.To determine the percentage of Thoroughbred racehorses that would be capable of racing performance after recovery from infectious pleuropneumonia. Methods: Retrospective case series. Methods: 70 Thoroughbred horses that had recovered from pleuropneumonia. Only horses 5 years old known to be in race training at the time of illness were included in the study. Results: Forty-three of the 70 (61%) horses raced after recovery, and 24 of the 43 (56%) won at least 1 race. Horses that required placement of an indwelling thoracic drain apparently did not have a worse prognosis than did horses that did...
Use of enzyme-linked immunosorbent assay to measure thrombin-antithrombin III complexes in horses with colic.
American journal of veterinary research    April 1, 1996   Volume 57, Issue 4 456-462 
Topper MJ, Prasse KW.To evaluate new ELISA for measurement of thrombin-antithrombin III (TAT) concentration, and to correlate the values to other tests of hemostasis in horses with colic. Methods: Plasma TAT concentration and 8 other hemostasis analytes were measured in horses with colic at hospital admission and during the next 4 days. Retrospectively, data were analyzed by outcome, broad-category diagnosis, and clinical management, and for correlation between TAT and other assays. Methods: 100 horses with colic. Methods: Plasma samples were evaluated for TAT, fibrinogen, and fibrin degradation products concentra...
Medical treatment of horses with ileal impactions: 10 cases (1990-1994).
Journal of the American Veterinary Medical Association    March 15, 1996   Volume 208, Issue 6 898-900 
Hanson RR, Schumacher J, Humburg J, Dunkerley SC.To evaluate clinical and laboratory findings for horses treated medically for ileal impactions. Methods: Retrospective case series. Methods: 10 horses with primary ileal impaction that were treated successfully with medical treatment alone. Methods: Medical records were reviewed for all horses with naturally developing ileal impaction seen at our hospital between 1990 and 1994. Results: Transrectal palpation revealed an impaction in the midabdominal area in all horses. Generalized distention of the small intestine was evident in 6 horses, whereas 4 horses were examined early in the course of t...
Radiographic and arthroscopic findings associated with subchondral lucency of the distal radial carpal bone in 71 horses.
Equine veterinary journal    March 1, 1996   Volume 28, Issue 2 93-97 doi: 10.1111/j.2042-3306.1996.tb01598.x
Dabareiner RM, White NA, Sullins KE.Case records and radiographs of 71 horses with subchondral lucency, without radiographic evidence of fracture, located on the distal radial carpal bone were examined retrospectively. All horses had lameness and/or joint effusion referable to the carpus. Distal radial carpal bone subchondral lucency was found as a solitary lesion or as a lesion concurrent and symmetric to a contralateral distal radial carpal bone chip fracture. The lesion appeared radiographically as a lucency or shadow on the distal dorsal margin of the radial carpal bone and was most evident on the flexed lateromedial and dor...
Ultrasonographic anatomy of the dorsal and abaxial aspects of the equine fetlock.
Equine veterinary journal    January 1, 1996   Volume 28, Issue 1 54-62 doi: 10.1111/j.2042-3306.1996.tb01590.x
Denoix JM, Jacot S, Bousseau B, Perrot P.This paper describes normal ultrasound images of the soft tissues of the dorsal and abaxial aspects of the equine fetlock. The palmar aspect of the fetlock is not discussed because it is related to the suspensory apparatus and flexor tendon anatomy which has been previously described. Ultrasound scanning was performed with 7.5 MHz linear or 10 MHz sector probes and recorded on 7.5 cm U-matic videocassettes allowing further retrospective data analysis, computer manipulation and good image reproducibility. Sagittal, parasagittal, frontal and transverse ultrasound scans of 13 lameness free mature...
Double-plate fixation of comminuted fractures of the second phalanx in horses: 10 cases (1985-1993).
Journal of the American Veterinary Medical Association    December 1, 1995   Volume 207, Issue 11 1458-1461 
Crabill MR, Watkins JP, Schneider RK, Auer JA.To determine the technique used, and the outcome for, double-plate fixation of comminuted fractures of the second phalanx of horses. Methods: Retrospective analysis of medical records. Methods: 10 horses with comminuted fractures of the second phalanx that were treated by use of double-plate fixation. Methods: Two 4- to 6-hole dynamic compression plates were abaxially placed to achieve arthrodesis of the proximal interphalangeal joint and fixation of the fracture of the second phalanx. Results: Arthrodesis and fracture healing were detected in all horses. Conclusions: Horses with comminuted fr...
Loop colostomy for treatment of grade-3 rectal tears in horses: seven cases (1983-1994).
Journal of the American Veterinary Medical Association    November 1, 1995   Volume 207, Issue 9 1201-1205 
Blikslager AT, Bristol DG, Bowman KF, Engelbert TA.To determine the feasibility of performing a single-incision loop colostomy for treatment of grade-3 rectal tears in horses. Methods: Retrospective case series. Methods: Seven adult horses with grade-3 rectal tears. Methods: A single-incision loop colostomy was performed with horses under general anesthesia (n = 6) or while restrained in standing stocks (n = 1). The rectal tear was lavaged via an endoscope. The colostomy was resected after the rectal tear healed. Results: Rectal tears ranged from 4 to 10 cm in diameter and were > 25 cm proximal to the anus. All horses survived colostomy surger...
Complications of celiotomy incisions in horses.
Veterinary surgery : VS    November 1, 1995   Volume 24, Issue 6 506-514 doi: 10.1111/j.1532-950x.1995.tb01362.x
Wilson DA, Baker GJ, Boero MJ.Complications of celiotomy incisions were evaluated retrospectively in 274 horses that survived at least 1 month after surgery, or died or were euthanatized within 1 month of surgery, as a direct result of these complications. Horses were divided into four groups; group A, a ventral median celiotomy for intestinal disease; group B, ventral median celiotomy for nonintestinal disease; group C, repair of an umbilical hernia; and group D, celiotomy in a region other than the midline. Specific incisional complications were peri-incisional edema, drainage, incisional abscess, suture sinus, and dehis...
[Differentiated prognosis in the colicky horse].
Tierarztliche Praxis    October 1, 1995   Volume 23, Issue 5 475-480 
Ebert R.In a retrospective study on 271 horses with colic the prediction about the outcome of the disease was made by a discriminating analysis. The best combination of quantitative prognostic parameters was capillary refill time, hematocrit, lactate and anion gap, with 90% correct predictions. In comparison with individually prognostic parameters, the combined prognosis constantly reached a higher percentage of correct predictions, the exact value resulting in 89%. Moreover, survival was better predictable than death.
Equine melanocytic tumors: a retrospective study of 53 horses (1988 to 1991).
Journal of veterinary internal medicine    September 1, 1995   Volume 9, Issue 5 291-297 doi: 10.1111/j.1939-1676.1995.tb01087.x
Valentine BA.A study of 57 cutaneous melanocytic tumors from 53 horses revealed 4 distinct clinical syndromes: melanocytic nevus, dermal melanoma, dermal melanomatosis, and anaplastic malignant melanoma. Melanocytic nevus and anaplastic melanoma each had histopathologic features that distinguished them from dermal melanoma and dermal melanomatosis. Dermal melanoma and dermal melanomatosis were histologically similar but could be differentiated by their clinical features. Melanocytic nevi were diagnosed in 29 horses with an average age of 5 years; they were solitary, superficial masses that occurred in both...
Scintigraphy for diagnosis of avulsions of the origin of the suspensory ligament in horses: 51 cases (1980-1993).
Journal of the American Veterinary Medical Association    September 1, 1995   Volume 207, Issue 5 608-611 
Edwards RB, Ducharme NG, Fubini SL, Yeager AE, Kallfelz FA.The medical records of 34 horses with a diagnosis of avulsion of the origin of the suspensory ligament that had been admitted to the veterinary medical teaching hospital between 1980 and 1993 were identified. In addition to clinical examination, 21 of 34 horses had scintigraphy and radiography performed during their examination. The usefulness of scintigraphy and radiography were assessed by comparing the initial findings reported in the medical record to those obtained in a retrospective review of the images. Thirty other horses with scintigraphic lesions of the proximal aspect of the third m...
Case-control study of risk factors for development of pleuropneumonia in horses.
Journal of the American Veterinary Medical Association    August 1, 1995   Volume 207, Issue 3 325-328 
Austin SM, Foreman JH, Hungerford LL.Risk factors for development of pleuropneumonia were determined by reviewing medical records of 45 horses with pleuropneumonia and 180 control horses examined between Jan 1, 1980 and Jan 1, 1990. Factors considered included age, breed, sex, occupation, transport farther than 500 miles within the previous week, racing within the previous 48 hours, viral respiratory tract infection or exposure to horses with viral respiratory tract disease within the previous 2 weeks, and vaccination against influenza or rhinopneumonitis within the previous 6 months. Results indicated that Thoroughbreds were at ...
Medical management of right dorsal colitis in 5 horses: a retrospective study (1987-1993).
Journal of veterinary internal medicine    July 1, 1995   Volume 9, Issue 4 272-276 doi: 10.1111/j.1939-1676.1995.tb01079.x
Cohen ND, Carter GK, Mealey RH, Taylor TS.Right dorsal colitis in horses has been associated with administration of phenylbutazone. Although reports of right dorsal colitis in this species have described surgical treatment associated with a poor prognosis, we have had success treating this condition medically. This report describes 5 horses with right dorsal colitis confirmed during celiotomy that were initially managed medically. All horses had a history of intermittent abdominal pain; weight loss was noted in only 1 horse. The doses (2.0 to 4.6 mg/kg PO bid) and duration (5 to 30 days) of administration of phenylbutazone were not un...
Serum protein concentrations in horses with severe liver disease: a retrospective study and review of the literature.
Journal of veterinary internal medicine    May 1, 1995   Volume 9, Issue 3 154-161 doi: 10.1111/j.1939-1676.1995.tb03289.x
Parraga ME, Carlson GP, Thurmond M.The present retrospective study was undertaken to determine the frequency of hypoproteinemia and hypoalbuminemia in horses with natural occurring severe liver disease. The study represents a review of case records and laboratory data of 84 horses presented with acute or chronic liver disease to the University of California Veterinary Medical Teaching Hospital between 1973 and 1991. Forty horses (48%) had serum protein concentrations above the maximum reference value (7.7 g/dL). The increase in serum protein concentration was associated with hyperglobulinemia (P = .00005, R2 = .80). Only 13% (1...
Retropharyngeal lymph node infection in horses: 46 cases (1977-1992).
Australian veterinary journal    May 1, 1995   Volume 72, Issue 5 161-164 doi: 10.1111/j.1751-0813.1995.tb03504.x
Golland LC, Hodgson DR, Davis RE, Rawlinson RJ, Collins MB, McClintock SA, Hutchins DR.A retrospective study of 46 horses with retropharyngeal lymph node (RPLN) infection presented to the Rural Veterinary Centre between 1977 and 1992 was undertaken. Horses aged less than one year were most commonly represented (46%). Thirty-nine percent of cases had been exposed to horses with confirmed or suspected strangles (Streptococcus equi subsp equi infection) within the previous 8 weeks. Most frequent signs were unilateral or bilateral swelling of the throat region (65%), respiratory stertor/dyspnoea (35%), purulent nasal discharge (20%), inappetence and signs of depression (15%), and dy...
Wesselsbron virus antibody in domestic animals in Nigeria: retrospective and prospective studies.
The new microbiologica    April 1, 1995   Volume 18, Issue 2 151-162 
Baba SS, Fagbami AH, Ojeh CK, Olaleye OD, Omilabu SA.Retrospective and prospective serological surveys to determine the prevalence of Wesslsbron (WSL) virus infections in animal populations were carried out in different vegetational zones in Nigeria. Sera from 1,492 animals comprising 292 camels, 81 horses, 4 donkeys, 320 cattle, 235 sheep, 260 goats, 114 pigs, 101 dogs and 85 domestic fowls were assayed by haemagglutination-inhibition (HI) test for presence of antibodies to WSL virus and other flavivirus antigens: Yellow Fever (YF), Potiskum (POT), Banzi (BAN), Uganda S (UGS) and West Nile (WN) viruses. Four hundred and eighty one (32%) of the ...
Intraperitoneal use of sodium carboxymethylcellulose in horses undergoing exploratory celiotomy.
Veterinary surgery : VS    March 1, 1995   Volume 24, Issue 2 112-117 doi: 10.1111/j.1532-950x.1995.tb01304.x
Mueller PO, Hunt RJ, Allen D, Parks AH, Hay WP.The effect of intraperitoneal sodium carboxymethylcellulose (SCMC) administration on clinical outcome and survival was evaluated in horses undergoing exploratory celiotomy for acute gastrointestinal disease. Comparison of variables was made retrospectively between 44 horses that had SCMC and 92 horses (controls) not treated with SCMC. Mean age, body weight, heart rate, packed cell volume and plasma total protein of horses at admission, and convalescent period were not significantly different between control and SCMC groups. No significant differences were noted between control horses and SCMC ...
Fibrosing granulomas in the equine liver and peritoneum: a retrospective morphologic study. Buergelt CD, Greiner EC.Fibrosing granulomas were found in the liver and occasionally on the intestinal and diaphragmatic serosae and in the lung of 11 horses submitted for necropsy. Although these granulomas were considered incidental findings in most of the horses, they had caused liver failure in 1 horse. The granulomas typically were characterized by a dense collagenous core that frequently was mineralized. The periphery contained a rim of inflammatory cells. Only in 1 of the 11 horses was there evidence of an egg shell suggestive of schistosomes. Schistosomal eggs were not detected in the feces of the horses. Th...
A retrospective study of increased plasma progestagen concentrations in compromised neonatal foals.
Reproduction, fertility, and development    January 1, 1995   Volume 7, Issue 3 567-575 doi: 10.1071/rd9950567
Rossdale PD, Ousey JC, McGladdery AJ, Prandi S, Holdstock N, Grainger L, Houghton E.Plasma progestagen concentrations were measured daily by radioimmunoassay (RIA) in 35 sick foals for the duration of their illness. The foals were divided into three groups on the basis of time to stand after birth. Foals were given intensive care treatment according to the severity of their illness. Plasma and urine concentrations of pregnenolone (P5) and pregnenediol (P5 beta beta) were measured by gas chromatography--mass spectrometry; plasma cortisol concentrations were measured by RIA and the foals' renal and respiratory status were assessed by creatinine clearance ratios and arterial oxy...
Observations on the anatomy and pathology of the palmar intercarpal ligaments in the middle carpal joints of thoroughbred racehorses.
Equine veterinary journal    November 1, 1994   Volume 26, Issue 6 486-491 doi: 10.1111/j.2042-3306.1994.tb04055.x
Phillips TJ, Wright IM.Ten carpi from juvenile Thoroughbred horses were dissected in detail to record the anatomy of the palmar intercarpal ligaments (PICLs). These were found not to be substantially attached to the palmar carpal ligament. The lateral PICL was sited at the convergence of the palmar aspects of the third, fourth, intermediate and ulnar carpal bones and aligned predominantly in a proximodistal direction. The medial PICL had a large origin distally on the lateral aspect of the radial carpal bone (Cr) and attached to third (C3) and second (C2) carpal bones with apparently separate fibre orientations. Fib...
Presence of African horse sickness virus in equine tissues, as determined by in situ hybridization.
Veterinary pathology    November 1, 1994   Volume 31, Issue 6 689-694 doi: 10.1177/030098589403100609
Brown CC, Meyer RF, Grubman MJ.In a retrospective study, a negative-sense digoxigenin-labeled RNA probe, corresponding to the gene encoding nonstructural protein-1 of African horse sickness virus (AHSV) serotype 4, was applied to formalin-fixed, paraffin-embedded tissue taken from horses in the terminal stages of infection with AHSV. Fifteen infected ponies and one noninfected control were studied. Ponies exhibited a range of clinical signs and lesions. Thirteen ponies were infected with serotype 4, one with serotype 1, and one with serotype 2. Ponies were monitored clinically and euthanatized when severely clinically ill. ...
Management of equine sarcoids: 1975-93.
New Zealand veterinary journal    October 1, 1994   Volume 42, Issue 5 180-184 doi: 10.1080/00480169.1994.35816
McConaghy FF, Davis RE, Reppas GP, Rawlinson R J, McClintock SA, Hutchins DR, Hodgson DR.Treatment options for equine sarcoids are briefly reviewed and the results of a retrospective study of 63 cases of equine sarcoid (66 lesions) treated by clinicians from the Rural Veterinary Centre, Camden, Australia from 1975 to 1993 presented. Five different treatments were employed in the management of these 66 lesions, including surgical excision alone or in combination with cryotherapy, radiotherapy, immunotherapy and tumour transfer to a subcutaneous site on the neck. The majority of cases were treated with surgical excision alone (18/66), excision followed by cryotherapy (31/66) and imm...
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