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Topic:Risk Factors

Risk factors in horses refer to variables or conditions that increase the likelihood of disease, injury, or other adverse health outcomes in equine populations. These factors can be intrinsic, such as age, breed, and genetic predisposition, or extrinsic, including environmental conditions, management practices, and exposure to infectious agents. Understanding risk factors is important for developing preventive strategies and improving health management in horses. This page aggregates peer-reviewed research studies and scholarly articles that explore the identification, assessment, and mitigation of risk factors in equine health, with the aim of enhancing disease prevention and promoting overall well-being in horses.
A retrospective case-control study of horse falls in the sport of horse trials and three-day eventing.
Equine veterinary journal    March 18, 2003   Volume 35, Issue 2 139-145 doi: 10.2746/042516403776114180
Singer ER, Saxby F, French NP.Serious injuries to horses and riders in horse trials (HT) and three-day events (3DE) are usually associated with falls of horses, which invariably involve falls of the riders. Many potential causes for these falls have been discussed. Objective: The aim of this case-control study was to investigate the risk factors for horse falls on the cross-country phase of horse trials and three-day events. Methods: Using retrospective data, significant risk factors identified with unvariable analysis (P value <0.2) were entered into a multivariable logistic regression model. Significant risk factors (...
Risk factors associated with behavioural disorders of crib-biting, weaving and box-walking in Swiss horses.
Equine veterinary journal    March 18, 2003   Volume 35, Issue 2 158-163 doi: 10.2746/042516403776114216
Bachmann I, Audigé L, Staᆲher M.Studies on the prevalence of behavioural disorders in horses and on associated risk factors have revealed inconsistent results. There are many studies on the neuropharmacological, surgical or mechanical therapy of stereotypies, but little is known about their causation. Objective: To explore risk factors associated with the occurrence of behavioural disorders in horses. Methods: A sample of horse owners, selected randomly and representative for Switzerland, was contacted in a postal survey. Answers were provided for 622 stables (response rate 35.2%). Individual data of 2,341 horses were examin...
Case-control study of factors associated with excessive proportions of early fetal losses associated with mare reproductive loss syndrome in central Kentucky during 2001.
Journal of the American Veterinary Medical Association    March 7, 2003   Volume 222, Issue 5 613-619 doi: 10.2460/javma.2003.222.613
Dwyer RM, Garber LP, Traub-Dargatz JL, Meade BJ, Powell D, Pavlick MP, Kane AJ.To identify factors associated with excessive proportions of early fetal losses associated with mare reproductive loss syndrome in central Kentucky during 2001. Methods: Case-control study. Methods: Questionnaires were used to collect information on farm-, pasture-, and individual animal-level factors purportedly associated with mare reproductive loss syndrome. Data were collected for 133 farms (97 with excessive proportions of early feta losses and 36 control farms) representing 6,576 mares. Results: Factors significantly associated with an increased risk of excessive early fetal losses were ...
Evaluation of equine breeding farm characteristics as risk factors for development of Rhodococcus equi pneumonia in foals.
Journal of the American Veterinary Medical Association    February 25, 2003   Volume 222, Issue 4 467-475 doi: 10.2460/javma.2003.222.467
Chaffin MK, Cohen ND, Martens RJ.To identify farm characteristics as risk factors for the development of Rhodococcus equi pneumonia in foals. Methods: Prospective matched case-control study. Methods: 2,764 foals on 64 equine breeding farms with 9,991 horses. Methods: During 1997, participating veterinarians completed paired data collection forms, 1 for a farm with > or = 1 foal with R equi pneumonia and 1 for an unaffected control farm. Matched data were compared by use of conditional logistic regression analysis. Results: Farm characteristics found in bivariate analyses to be associated with increased risk for pneumonia caus...
Evaluation of equine breeding farm management and preventative health practices as risk factors for development of Rhodococcus equi pneumonia in foals.
Journal of the American Veterinary Medical Association    February 25, 2003   Volume 222, Issue 4 476-485 doi: 10.2460/javma.2003.222.476
Chaffin MK, Cohen ND, Martens RJ.To determine whether foal management practices, environmental management, and preventative health practices are risk factors for development of Rhodococcus equi pneumonia in foals. Methods: Prospective matched case-control study. Methods: 2,764 foals on 64 equine breeding farms with 9,991 horses. Methods: During 1997, participating veterinarians completed paired data collection forms for comparison; 1 for an affected farm (containing > or = 1 foal with pneumonia caused by R equi) and 1 for a control farm. Information collected pertained to stabling facilities, environmental management, foal hu...
Case-control study of late-term abortions associated with mare reproductive loss syndrome in central Kentucky.
Journal of the American Veterinary Medical Association    January 31, 2003   Volume 222, Issue 2 199-209 doi: 10.2460/javma.2003.222.199
Cohen ND, Carey VJ, Donahue JG, Seahorn JL, Donahoe JK, Williams DM, Harrison LR.To identify factors associated with abortions of mares during late gestation attributed to mare reproductive loss syndrome (MRLS). Methods: Case-control study. Methods: 282 broodmares from 62 farms in central Kentucky, including 137 mares that had late-term abortions (LTAs) associated with MRLS, 98 mares from the same farms that did not abort, and 48 mares that aborted from causes other than MRLS. Methods: Farm managers were interviewed to obtain data on a wide range of management practices and environmental exposures for the mares. Data for case and control horses were compared to identify ri...
Case-control study of early-term abortions (early fetal losses) associated with mare reproductive loss syndrome in central Kentucky.
Journal of the American Veterinary Medical Association    January 31, 2003   Volume 222, Issue 2 210-217 doi: 10.2460/javma.2003.222.210
Cohen ND, Donahue JG, Carey VJ, Seahorn JL, Piercy D, Donahoe JK, Williams DM, Brown SE, Riddle TW.To identify factors associated with abortions during early gestation classified as mare reproductive loss syndrome (MRLS). Methods: Case-control study. Methods: 324 broodmares from 43 farms in central Kentucky, including 121 mares from 25 farms that had early-term abortions (ETAs) associated with MRLS (case horses), 120 mares from the same farms but that did not abort, and 83 mares from 18 farms that were not severely Impacted by MRLS. Methods: Farm managers were interviewed to obtain data on various management practices and environmental exposures for the mares. Data for case and control hors...
A herd-level analysis of risk factors for antibodies to Sarcocystis neurona in Michigan equids.
Preventive veterinary medicine    January 28, 2003   Volume 57, Issue 1-2 7-13 doi: 10.1016/s0167-5877(02)00192-7
Rossano MG, Kaneene JB, Marteniuk JV, Banks BD, Schott HC, Mansfield LS.Equine protozoal myeloencephalitis (EPM) is a neurological disease of horses and ponies caused by infection of the central nervous system with the protozoan parasite Sarcocystis neurona. A herd-level analysis of a cross-sectional study of serum antibodies to S. neurona in Michigan equids was conducted, using data collected in 1997 for study that included 1121 equids from 98 Michigan horse farms. Our objective was to identify specific herd-level risk factors associated with seropositivity. We tested associations between herd seroprevalence and various farm-management practices (including feed-s...
Risk factors associated with colic in horses.
Veterinary research    December 25, 2002   Volume 33, Issue 6 641-652 doi: 10.1051/vetres:2002044
Gonçalves S, Julliand V, Leblond A.Many factors have been identified as risk factors for colic in horses in several epidemiological studies. The aim of our paper was to review the results of 12 epidemiological studies, in order to assess the impact of each risk factor for colic. According to the literature, the factors that increase the risk of colic are feeding practices (type and quality of food, type and changes of feeding), the intrinsic factors of horses (sex, age and breed), management (type and changes of housing and activity), medical history (a previous colic, administration of a medical treatment) and parasite control...
Incidence and risk factors for exertional rhabdomyolysis in thoroughbred racehorses in the United Kingdom.
The Veterinary record    December 14, 2002   Volume 151, Issue 21 623-626 doi: 10.1136/vr.151.21.623
McGowan CM, Fordham T, Christley RM.Telephone surveys of 34 racing yards with 1276 horses in training were made to establish the overall incidence of exertional rhabdomyolysis in the previous year. A case-control study was used to investigate the risk factors for the syndrome in 12 yards selected on the basis of the routine confirmation of diagnoses by the evaluation of the serum activities of creatine kinase and aspartate aminotransferase. The overall incidence of the syndrome was 6.7 per cent and 80 per cent of the trainers had at least one affected horse. In 74 per cent of the affected horses it frequently recurred, with an a...
Risk factors for the hazard of lameness in Danish Standardbred trotters.
Preventive veterinary medicine    November 27, 2002   Volume 56, Issue 2 105-117 doi: 10.1016/s0167-5877(02)00158-7
Vigre H, Chriél M, Hesselholt M, Falk-Rønne J, Kjaer Ersbøll A.A follow-up study focusing on health problems interfering with optimal training of Danish Standardbred trotters was conducted with the participation of seven professional trainers. Our aim was to estimate the incidence of health problems that cause interruptions of optimal training, and to identify associations between the hazard of lameness and selected risk factors. The study population was dynamic and contained data of 265 Standardbred trotters monitored during 5 months in 1997 and 1998. The horses were >or=2 years old. Optimal training was defined as when the horse followed scheduled tr...
Evidence of an association between inflammatory airway disease and EIPH in young Thoroughbreds during training.
Equine veterinary journal. Supplement    October 31, 2002   Issue 34 417-424 doi: 10.1111/j.2042-3306.2002.tb05459.x
Newton JR, Wood JL.In an epidemiological study of risk factors for exercise-induced pulmonary haemorrhage (EIPH) in young Thoroughbreds in the UK, in which 148 horses contributed 1614 horse-months of data, there were 64 (4%) episodes of endoscopically visible tracheal bleeding and 824 (51%) episodes of increased quantities of haemosiderophages in tracheal washes. There were increases in prevalence and risk of EIPH by both definitions with age from or = 4 years, season of sampling from winter (Nov-Jan) to autumn (Aug-Oct) and several different measures of airway inflammation, including tracheal mucus, neutrophil...
Associations between age or sex and prevalence of gastric ulceration in Standardbred racehorses in training.
Journal of the American Veterinary Medical Association    October 22, 2002   Volume 221, Issue 8 1156-1159 doi: 10.2460/javma.2002.221.1156
Rabuffo TS, Orsini JA, Sullivan E, Engiles J, Norman T, Boston R.To determine associations between age, sex, or medical treatment and prevalence and severity of gastric ulceration in Standardbred racehorses in training. Methods: Cross-sectional study. Methods: 224 Standardbred racehorses in training. Methods: Gastroscopy was performed on each horse, and mucosal ulceration was graded from 0 (normal mucosa, no lesions) to 3 (extensive, often coalescing, lesions with areas of deep ulceration). Associations between age, sex, or treatment and prevalence and severity of ulcers were evaluated. Results: Prevalence of gastric ulceration was 87%. Although there was l...
Risk factors and sources of variation in horse falls in steeplechase racing in the UK.
Preventive veterinary medicine    October 18, 2002   Volume 55, Issue 3 179-192 doi: 10.1016/s0167-5877(02)00098-3
Pinchbeck GL, Clegg PD, Proudman CJ, Morgan KL, Wood JL, French NP.We identified risk factors associated with falling during steeplechase racing. We used retrospective data from all steeplechase runs on UK racecourses during 1999: 10,866 starts with 647 horse falls. The relationship between continuous variables and falling was assessed using generalised additive models (GAMs). Polynomial fits then were included in a multilevel, multivariable logistic-regression model. The number of runners had a linear, positive association with the risk of falling. The distance of the race had a non-linear relationship with the risk of falling; the risk steadily increased in...
Factors associated with development of ileal impaction in horses with surgical colic: 78 cases (1986-2000).
Equine veterinary journal    October 3, 2002   Volume 34, Issue 5 464-468 doi: 10.2746/042516402776117773
Little D, Blikslager AT.Deal impaction is prevalent in the south-eastern USA, where feeding of Coastal Bermuda hay has been implicated as a risk factor. Alternatively, infection with the tapeworm Anoplocephala perfoliata has been identified as a risk factor for ileal impaction in the UK. We hypothesised that feeding Coastal Bermuda hay and failure to administer routinely an anthelmintic with efficacy against tapeworms would place horses at risk of developing ileal impaction in the USA. Seventy-eight horses, with surgically confirmed ileal impaction and 100 horses admitted for colic that did not have an ileal impactio...
Equine surgical colic: risk factors for postoperative complications.
Equine veterinary journal    October 3, 2002   Volume 34, Issue 5 444-449 doi: 10.2746/042516402776117791
French NP, Smith J, Edwards GB, Proudman CJ.The reason for undertaking this study was that postoperative complications of colic surgery lead to patient discomfort, prolonged hospitalisation and increased cost. Potential risk factors for the 6 most common postoperative complications (jugular thrombosis, ileus, re-laparotomy, wound suppuration, incisional herniation and colic) were evaluated using multivariable models. Jugular thrombosis was associated significantly with heart rate greater than 60 beats/min and with increased packed cell volume (PCV) at admission. The risk of postoperative ileus also increased with increasing PCV at admis...
Case control study to identify risk factors for simple colonic obstruction and distension colic in horses.
Equine veterinary journal    October 3, 2002   Volume 34, Issue 5 455-463 doi: 10.2746/042516402776117746
Hillyer MH, Taylor FG, Proudman CJ, Edwards GB, Smith JE, French NP.A case control study was performed to identify risk factors for colic caused by simple colonic obstruction and distension (SCOD) in the horse. Case horses were recruited from 2 veterinary school clinics. Control horses were population based and matched by time of year. A number of risk factors were considered in the following areas: general carer and premises information; exercise information; husbandry information (housing- and pasture-related); feeding information; breeding information; behavioural information; travel information; preventive medicine information and previous medical informat...
Long-term survival of equine surgical colic cases. Part 2: modelling postoperative survival.
Equine veterinary journal    October 3, 2002   Volume 34, Issue 5 438-443 doi: 10.2746/042516402776117881
Proudman CJ, Smith JE, Edwards GB, French NP.Colic surgery is a frequently performed operation with high postoperative mortality. This study was undertaken to identify variables associated with decreased postoperative survival. We used data from 321 horse years of postoperative survival time to model the probability of survival following recovery from colic surgery. Continuous variables were modelled using a 6 variable, penalised Cox regression model. This demonstrated approximately linear relationships between survival and the following variables: increase in packed cell volume (PCV), intestinal resection length, time to surgery (interv...
Surgical and postoperative factors influencing short-term survival of horses following small intestinal resection: 92 cases (1994-2001).
Equine veterinary journal    October 3, 2002   Volume 34, Issue 5 450-454 doi: 10.2746/042516402776117700
Morton AJ, Blikslager AT.Although short-term survival rates following small intestinal resection reportedly range from 48-88%, there is little information on predicting which horse may or may not survive small intestinal (SI) resection and anastomosis. The aim of this study was to identify factors that contribute to nonsurvival in horses following small intestinal resection. Medical records of horses which recovered from anaesthesia following SI resection were reviewed. Clinical and surgical variables were evaluated for their association with short-term survival using logistic regression and were reported as odds rati...
Risk factors for high endoparasitic burden and the efficiency of a single anthelmintic treatment of Danish horses.
Acta veterinaria Scandinavica    August 14, 2002   Volume 43, Issue 2 99-106 doi: 10.1186/1751-0147-43-99
Larsen MM, Lendal S, Chriél M, Olsen SN, Bjørn H.A questionnaire survey regarding endoparasite control practices in Danish horse herds was carried out in 1995. The participating veterinarians and herd owners were sampled using convenience and purposive sampling. In the analysis of risk factors for development of a high endoparasitic burden (> 200 eggs per gram faeces) 903 horses were sampled and the analysis of the efficiency of a single anthelmintic treatment was based on 605 horses. The following factors had a significant effect on the endoparasitic burden: herd type, age of the horses, use of pasture rotation, anthelmintic treatment of ho...
Evaluation of early fetal losses on four equine farms in central Kentucky: 73 cases (2001).
Journal of the American Veterinary Medical Association    July 3, 2002   Volume 220, Issue 12 1828-1830 doi: 10.2460/javma.2002.220.1828
Morehead JP, Blanchard TL, Thompson JA, Brinsko SP.To determine features of an early fetal loss (EFL) syndrome and evaluate potential risk factors for EFL in Thoroughbred broodmares on 4 farms in central Kentucky. Methods: Retrospective study. Methods: 288 pregnant broodmares. Methods: Year-2001 breeding records for 288 Thoroughbred broodmares were examined. Early fetal loss was defined as loss of a fetus that was viable at > or = 40 days of gestation but was subsequently lost by 5 months of gestation. Results: Overall 2001 EFL rate was 25% (73/288), median gestational age at time of fetal loss was 77 days, and median date of loss was May 7...
Effect of experience on rodeo injury.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine    February 21, 2002   Volume 12, Issue 1 30-35 doi: 10.1097/00042752-200201000-00009
Butterwick DJ, Meeuwisse WH.To document injury rates, severity, and relative risk during five competitive seasons of Canadian professional rodeo, between experienced (saddle bronc [SB], bareback [BB], and bull riders [BR]) and inexperienced (novice saddle bronc [NSB], novice bareback [NBB], and boys' steer riders [BSR]) rough stock competitors. Methods: Prospective cohort study. Methods: Canadian professional rodeo competition. Methods: Experienced competitors included professional cowboys from Australia, Brazil, New Zealand, the United States, and Canada. Inexperienced competitors included cowboys from Canada and the Un...
Risks associated with the use of herbs and other dietary supplements.
The Veterinary clinics of North America. Equine practice    January 10, 2002   Volume 17, Issue 3 455-vii doi: 10.1016/s0749-0739(17)30045-7
Poppenga RH.The use of dietary supplements (herbs, vitamins, minerals, amino acids, enzymes, and other compounds) is common in horses. They are heavily marketed in retail stores, magazines, and on the Internet. There is the perception that since these compounds are "natural" they are devoid of toxicity, and, therefore, they are safe to use. Some of the active compounds in supplements, however, have inherent toxicity, and using them may cause adverse effects. Even relatively non-toxic ingredients may be toxic if used over-zealously or for a long period of time. By and large, these compounds have not been t...
Risk factors associated with the presence of Sarcocystis neurona sporocysts in opossums (Didelphis virginiana).
Veterinary parasitology    January 5, 2002   Volume 102, Issue 3 179-184 doi: 10.1016/s0304-4017(01)00549-0
Rickard LG, Black SS, Rashmir-Raven A, Hurst G, Dubey JP.Sarcocystis neurona is the most important cause of equine protozoal myeloencephalitis (EPM) in horse in the Americas. The only known definitive host for this parasite in the United States is the opossum (Didelphis virginiana); however, despite the importance of the disease, the epidemiology of the parasite in the definitive host is poorly understood. To begin addressing these data gaps, potential risk factors were evaluated for their association with the presence of sporocysts of S. neurona in opossums live-trapped in March 1999 and November 1999 to May 2000. Sporocysts of S. neurona were foun...
Exercise alters the immune response to equine influenza virus and increases susceptibility to infection.
Equine veterinary journal    January 5, 2002   Volume 33, Issue 7 664-669 doi: 10.2746/042516401776249417
Folsom RW, Littlefield-Chabaud MA, French DD, Pourciau SS, Mistric L, Horohov DW.Equine influenza virus remains a major health concern for the equine industry in spite of ongoing vaccination programmes. Previous work has shown that the immune system of horses can be affected by strenuous exercise. The possible adverse consequence of exercise-induced alterations in lymphocyte responses measured in vitro was unknown. Here we demonstrate that subjecting vaccinated ponies to a 5 day strenuous exercise programme results in a significant suppression of their T cell-mediated immune response to equine influenza virus as measured by decreased lymphoproliferation and gamma interfero...
Fractures–a preventable hazard of racing thoroughbreds?
Veterinary journal (London, England : 1997)    December 26, 2001   Volume 163, Issue 1 19-29 doi: 10.1053/tvjl.2001.0610
Riggs CM.Fractures are a common cause of loss among Thoroughbred racehorses. A large proportion of these injuries occurs in the absence of a specific traumatic event and show typical characteristics of stress fractures. The fractures show a high degree of consistency in their morphology; they frequently share the same locations as incomplete cracks and they are often associated with pre-existing pathology (periosteal and endosteal new bone formation and intracortical remodelling). Bone is able to adapt to changes in its mechanical environment. Studies of the Thoroughbred racehorse show modification of ...
Feeding practices associated with colic in horses.
Journal of the American Veterinary Medical Association    November 29, 2001   Volume 219, Issue 10 1419-1425 doi: 10.2460/javma.2001.219.1419
Hudson JM, Cohen ND, Gibbs PG, Thompson JA.To determine whether specific feeding practices were associated with development of colic in horses. Methods: Prospective matched case-control study. Methods: 364 horses examined by veterinarians in private practice in Texas because of colic (cases; n = 182) or any other reason (controls; 182). Methods: Participating veterinarians were sent forms at the beginning of the study to collect information on signalment, feeding management practices, farm management practices, and preventive medical treatments. Case and control horses were compared by use of conditional logistic regression to identify...
Seasonality and relative abundance of Tabanidae (Diptera) captured on horses in the Pantanal, Brazil.
Memorias do Instituto Oswaldo Cruz    October 31, 2001   Volume 96, Issue 7 917-923 doi: 10.1590/s0074-02762001000700006
Barros AT.Once a month, from June 1992 to May 1993, collections of tabanids on horse were conducted in the Nhecolândia, Pantanal State of Mato Grosso do Sul, Brazil. Tabanid catches using hand nets were conducted from sunrise to sunset at grassland and cerradão (dense savanna) habitats. A total of 3,442 tabanids from 21 species,12 genera, and 3 subfamilies were collected. Although species abundance varied seasonally depending on habitat, no habitat specificity was observed for the most abundant species. In the grassland, 1,625 (47.2%) tabanids belonging to 19 species were collected, while 1,817 (52.8%...
Epidemiology of equine grass sickness: a literature review (1909-1999).
The Veterinary record    September 26, 2001   Volume 149, Issue 10 293-300 doi: 10.1136/vr.149.10.293
McCarthy HE, Proudman CJ, French NP.The geographical spread of grass sickness between 1909 and 1999, particularly in England and Wales, is described, and the experimental investigations to identify a causal agent are summarised. The epidemiological techniques used to investigate grass sickness vary from clinical observations, to more advanced methods such as case-control studies using logistic regression analyses. Several risk factors for grass sickness have been reported consistently (age, time of year and recent movement to new pasture or premises) and several others have been reported for which the findings remain inconsisten...
The prediction of stress fractures using a ‘stressed volume’ concept.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society    September 20, 2001   Volume 19, Issue 5 919-926 doi: 10.1016/S0736-0266(01)00009-2
Taylor D, Kuiper JH.This paper addresses an anomaly which exists in the current literature regarding stress fractures. Analysis of the data on fatigue strength of bone samples in vitro would conclude that these fractures should never occur at the strain levels known to occur in vivo. This anomaly can be resolved by including in the analysis the effect of stressed volume, whereby larger volumes of material are expected to have worse fatigue properties. A Weibull analysis was used to predict the probability of failure, Pf; this was an upper-bound prediction because it did not include the effects of remodelling and ...
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