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Topic:Risk Factors

Risk factors in horses refer to variables or conditions that increase the likelihood of disease, injury, or other adverse health outcomes in equine populations. These factors can be intrinsic, such as age, breed, and genetic predisposition, or extrinsic, including environmental conditions, management practices, and exposure to infectious agents. Understanding risk factors is important for developing preventive strategies and improving health management in horses. This page aggregates peer-reviewed research studies and scholarly articles that explore the identification, assessment, and mitigation of risk factors in equine health, with the aim of enhancing disease prevention and promoting overall well-being in horses.
Estimate of the national incidence of and operation-level risk factors for colic among horses in the United States, spring 1998 to spring 1999.
Journal of the American Veterinary Medical Association    July 7, 2001   Volume 219, Issue 1 67-71 doi: 10.2460/javma.2001.219.67
Traub-Dargatz JL, Kopral CA, Seitzinger AH, Garber LP, Forde K, White NA.To estimate the national incidence of, operation-level risk factors for, and annual economic impact of colic among horses in the United States during 1998 and 1999. Methods: Epidemiologic survey. Methods: 21,820 horses on 1,026 horse operations in 28 states. Methods: Horses were monitored for colic for 1 year, and results were recorded in a log that was collected quarterly. Operation-level data were collected via 4 on-site personal interviews. Associations between colic and independent variables adjusted for size of operation were determined. Results: Annual national incidence of colic in the ...
Risk factors associated with development of postoperative ileus in horses.
Journal of the American Veterinary Medical Association    July 7, 2001   Volume 219, Issue 1 72-78 doi: 10.2460/javma.2001.219.72
Roussel AJ, Cohen ND, Hooper RN, Rakestraw PC.To determine risk factors associated with development of postoperative ileus in horses undergoing surgery for colic. Methods: Case-control study. Methods: 69 horses that developed ileus after surgery for colic and 307 horses that did not develop postoperative ileus. Methods: Signalment, history, clinicopathologic data, treatment, lesions, and outcome were obtained from medical records. Results: Variables associated with increased risk of postoperative ileus included age > 10 years, Arabian breed, PCV > or = 45%, high serum concentrations of protein and albumin, anesthesia > 2.5 hours'...
Frequency of and risk factors for epistaxis associated with exercise-induced pulmonary hemorrhage in horses: 251,609 race starts (1992-1997).
Journal of the American Veterinary Medical Association    May 10, 2001   Volume 218, Issue 9 1462-1464 doi: 10.2460/javma.2001.218.1462
Takahashi T, Hiraga A, Ohmura H, Kai M, Jones JH.To determine the frequency of epistaxis during or after racing among racehorses and identify factors associated with development of epistaxis. Methods: Retrospective study. Methods: 247,564 Thoroughbred and 4,045 Anglo-Arab race starts. Methods: Race start information (breed, age, sex, racing distance, and race type) was obtained for Thoroughbred and Anglo-Arab horses racing in Japan Racing Association-sanctioned races between 1992 and 1997. All horses that raced were examined by a veterinarian within 30 minutes of the conclusion of the race; any horse that had blood at the nostrils was examin...
Risk factors to tick infestations and their occurrence on horses in the state of São Paulo, Brazil.
Veterinary parasitology    May 5, 2001   Volume 97, Issue 1 1-14 doi: 10.1016/s0304-4017(01)00387-9
Labruna MB, Kerber CE, Ferreira F, Faccini JL, De Waal DT, Gennari SM.From December 1998 to March 1999, 40 stud farms were studied in the state of São Paulo, Brazil. During visits to farms, horses reared under grazing conditions were examined for the presence of ticks. On each farm visit, horse pastures were closely inspected and a questionnaire was given to the farm supervisor with the purpose of gaining information about ecological and management variables (independent variables) that could be associated with the presence and infestation levels of ticks on the farm (dependent variables). Three tick species were found during the study. Anocentor nitens, Amblyo...
Risk factors for and outcomes of noncatastrophic suspensory apparatus injury in Thoroughbred racehorses.
Journal of the American Veterinary Medical Association    April 25, 2001   Volume 218, Issue 7 1136-1144 doi: 10.2460/javma.2001.218.1136
Hill AE, Stover SM, Gardner IA, Kane AJ, Whitcomb MB, Emerson AG.To evaluate effects of toe grabs, exercise intensity, and distance traveled as risk factors for subclinical to mild suspensory apparatus injury (SMSAI) in Thoroughbred racehorses and to compare incidence of severe musculoskeletal injury (MSI) in horses with and without SMSAI. Methods: Nested case-control study. Methods: 219 Thoroughbred racehorses racing or in race training. Methods: Racehorses were examined weekly for 90 days to determine incidence of suspensory ligament injury and monitor horseshoe characteristics. Every horse's exercise speeds and distances were recorded daily. Conditional ...
A multicenter, matched case-control study of risk factors for equine laminitis.
Preventive veterinary medicine    April 20, 2001   Volume 49, Issue 3-4 209-222 doi: 10.1016/s0167-5877(01)00188-x
Alford P, Geller S, Richrdson B, Slater M, Honnas C, Foreman J, Robinson J, Messer M, Roberts M, Goble D, Hood D, Chaffin M.Risk factors for equine laminitis were examined in a prospective case-control study of the 258 cases seen at six collaborating veterinary teaching hospitals over a 32-month period. Case-control pairs were matched on institution, clinician, and season of diagnosis. The 90% of case-control pairs (78 acute, 155 chronic) that had complete data for age, gender, and breed were used in separate conditional logistic-regression models for acute and chronic laminitis. There was an increase in risk for horses with acute laminitis from 5 to 7 years of age (OR 4.7, 95% CI 1.3-16) and from 13 to 31 years of...
Factors associated with Salmonella shedding among equine colic patients at a veterinary teaching hospital.
Journal of the American Veterinary Medical Association    March 31, 2001   Volume 218, Issue 5 740-748 doi: 10.2460/javma.2001.218.740
Kim LM, Morley PS, Traub-Dargatz JL, Salman MD, Gentry-Weeks C.To evaluate factors potentially associated with fecal Salmonella shedding among equine patients hospitalized for colic at a veterinary teaching hospital and to determine the effects of probiotic treatment on fecal Salmonella shedding and clinical signs. Methods: Longitudinal study and controlled trial. Methods: 246 equine colic patients. Methods: History and medical information were obtained from patient records. Fecal and environmental samples were submitted for aerobic bacterial culture for Salmonella enterica. Fifty-one patients were treated with a commercially available probiotic; 46 were ...
Coughing in thoroughbred racehorses: risk factors and tracheal endoscopic and cytological findings.
The Veterinary record    March 10, 2001   Volume 148, Issue 4 99-104 doi: 10.1136/vr.148.4.99
Christley RM, Hodgson DR, Rose RJ, Hodgson JL, Wood JL, Reid SW.A matched case-control study was made of 100 thoroughbred horses which were coughing and 148 control horses which were free of clinical signs of respiratory tract disease. The variables identified by multivariable conditional logistic regression as being significantly associated with coughing included age (the risk decreased with age), the stage of training (horses in early training were at greatest risk), the time since the last race (horses that had never raced were at greatest risk) and the time since they were last transported (horses transported more than 14 days previously were more like...
Risk factors associated with hindlimb lameness and degenerative joint disease in the distal tarsus of Icelandic horses.
Equine veterinary journal    February 24, 2001   Volume 33, Issue 1 84-90 doi: 10.2746/042516401776767502
Axelsson M, Björnsdottir S, Eksell P, Häggström J, Sigurdsson H, Carlsten J.The aim of this study was to evaluate potential risk factors associated with hindlimb lameness and radiographic signs of degenerative joint disease (DJD) in the distal tarsus in Icelandic horses. The material consisted of riding horses (n = 420) age 6-12 years sired by 17 selected sires representing all major breeding lines, and of riding horses (n = 194) in the same age range sired by other sires. The examination protocol included the following: interview with owners/trainers, assessment of conformation, motion evaluation and radiographic examination. At the interview, data related to factors...
Risk factors for reduced postoperative fecal output in horses: 37 cases (1997-1998).
Journal of the American Veterinary Medical Association    February 24, 2001   Volume 218, Issue 3 414-420 doi: 10.2460/javma.2001.218.414
Little D, Redding WR, Blikslager AT.To determine prevalence and risk factors for development of ileus of the large intestine after surgery in horses, identified by reduced postoperative fecal output (RPFO). Methods: Retrospective study. Methods: 37 horses that developed RPFO after undergoing general anesthesia for reasons unrelated to the gastrointestinal tract. Methods: Fecal output was obtained from medical records as number of defecations per 24-hour period after surgery; RPFO was defined as < or = 3 defecations per 24-hour period after surgery. The reference population included 48 horses that defecated > or = 4 times during ...
Equine protozoal myeloencephalitis.
The Veterinary clinics of North America. Equine practice    February 24, 2001   Volume 16, Issue 3 405-425 doi: 10.1016/s0749-0739(17)30086-x
MacKay RJ, Granstrom DE, Saville WJ, Reed SM.Recent advances in the understanding of the parasite life cycle, epidemiology, clinical signs, diagnosis, treatment, and prevention of EPM are reviewed. The NAHMS Equine '98 study and a controlled retrospective study from The Ohio State University College of Veterinary Medicine identified a number of risk factors associated with development of the disease. The national annual incidence of EPM was 1% or less depending on the primary use of the animals. Increased disease risk was associated with age (1-5 and > 13 years of age), season (lowest in winter months and increasing with ambient tempe...
The seroprevalence of antibodies to Sarcocystis neurona in Michigan equids.
Preventive veterinary medicine    January 13, 2001   Volume 48, Issue 2 113-128 doi: 10.1016/s0167-5877(00)00190-2
Rossano MG, Kaneene JB, Marteniuk JV, Banks BD, Schott HC, Mansfield LS.A cross-sectional study of serum antibodies to Sarcocystis neurona (the etiologic agent of equine protozoal myeloencephalitis, EPM) was performed on Michigan equids. Our objectives were to determine the seroprevalence of antibodies to S. neurona in Michigan equids and to identify specific risk factors for seropositivity. A random, weighted sample of Michigan horse farms (stratified by the state's opossum (Didelphis virginiana) population and the number of equids on each operation) was selected. Ninety-eight equine-operation owners agreed to participate, and blood collection occurred from late ...
Race-start characteristics and risk of catastrophic musculoskeletal injury in Thoroughbred racehorses.
Journal of the American Veterinary Medical Association    January 10, 2001   Volume 218, Issue 1 83-86 doi: 10.2460/javma.2001.218.83
Hernandez J, Hawkins DL, Scollay MC.To identify race-start characteristics associated with catastrophic musculoskeletal (MS) injury in Thoroughbred racehorses at 2 racetracks in Florida during 1995 through 1998. Methods: Matched case-control study. Methods: 97 Thoroughbreds (case horses) that incurred a catastrophic MS injury during racing and 388 Thoroughbreds (control horses) randomly selected from noninjured participants and matched on the basis of racetrack and year. Methods: Incidence of MS injury was calculated for all race meets at 2 racetracks in Florida from 1995 through 1998. Race-start characteristics were compared am...
Animal health risk assessment in theory and practice.
Journal of the American Veterinary Medical Association    January 2, 2001   Volume 217, Issue 12 1837-1842 doi: 10.2460/javma.2000.217.1837
Fite RW.No abstract available
Analysis of risk factors for the development of equine protozoal myeloencephalitis in horses.
Journal of the American Veterinary Medical Association    October 24, 2000   Volume 217, Issue 8 1174-1180 doi: 10.2460/javma.2000.217.1174
Saville WJ, Reed SM, Morley PS, Granstrom DE, Kohn CW, Hinchcliff KW, Wittum TE.To investigate risk factors for development of equine protozoal myeloencephalitis (EPM) in horses. Methods: Case-control study. Methods: 251 horses admitted to The Ohio State University Veterinary Teaching Hospital from 1992 to 1995. Methods: On the basis of clinical signs of neurologic disease and detection of antibody to Sarcocystis neurona or S neurona DNA in cerebrospinal fluid, a diagnosis of EPM was made for 251 horses. Two contemporaneous series of control horses were selected from horses admitted to the hospital. One control series (n = 225) consisted of horses with diseases of the neu...
Evaluation of risk factors associated with clinical improvement and survival of horses with equine protozoal myeloencephalitis.
Journal of the American Veterinary Medical Association    October 24, 2000   Volume 217, Issue 8 1181-1185 doi: 10.2460/javma.2000.217.1181
Saville WJ, Morley PS, Reed SM, Granstrom DE, Kohn CW, Hinchcliff KW, Wittum TE.To investigate risk factors for use in predicting clinical improvement and survival of horses with equine protozoal myeloencephalitis (EPM). Methods: Longitudinal epidemiologic study. Methods: 251 horses with EPM. Methods: Between 1992 and 1995, 251 horses with EPM were admitted to our facility. A diagnosis of EPM was made on the basis of neurologic abnormalities and detection of antibody to Sarcocystis neurona or S neurona DNA in CSF. Data were obtained from hospital records and through telephone follow-up interviews. Factors associated with clinical improvement and survival were analyzed, us...
Attitudes of Australian veterinarians about the cause and treatment of lower-respiratory-tract disease in racehorses.
Preventive veterinary medicine    July 29, 2000   Volume 46, Issue 3 149-159 doi: 10.1016/s0167-5877(00)00150-1
Christley RM, Rose RJ, Hodgson DR, Reid SW, Evans S, Bailey C, Hodgson JL.A questionnaire was administered to members of the Australian Equine Veterinary Association to investigate their attitudes and behaviours regarding the cause, diagnosis and treatment of lower-respiratory-tract disease in racehorses. The most-important perceived risk factors related to the level of exposure and resistance to infectious agents, whereas factors associated with racing and climatic factors were lower ranked. By far the most-commonly implicated primary cause of disease was respiratory viruses. However, specific diagnostic tests (such as viral serology or virus isolation) were rarely...
Diagnosis and management of abnormal embryonic development characterized by formation of an embryonic vesicle without an embryo in mares.
Journal of the American Veterinary Medical Association    July 26, 2000   Volume 217, Issue 1 58-63 doi: 10.2460/javma.2000.217.58
Vanderwall DK, Squires EL, Brinsko SP, McCue PM.To determine the incidence, ultrasonographic characteristics, and risk factors associated with embryonic development characterized by formation of an embryonic vesicle without an embryo in mares. Methods: Prevalence survey. Methods: 159 pregnant mares. Methods: From 1994 to 1998, mares between 11 and 40 days after ovulation with normal and abnormal embryonic development were examined ultrasonographically, and characteristics of each conceptus were recorded. Results: The incidence of abnormal embryonic development in mares characterized by formation of an embryonic vesicle without an embryo was...
Risk of adverse effects in pneumonic foals treated with erythromycin versus other antibiotics: 143 cases (1986-1996).
Journal of the American Veterinary Medical Association    July 26, 2000   Volume 217, Issue 1 68-73 doi: 10.2460/javma.2000.217.68
Stratton-Phelps M, Wilson WD, Gardner IA.To determine whether foals with pneumonia that were treated with erythromycin, alone or in combination with rifampin or gentamicin, had a higher risk of developing adverse effects, compared with foals treated with trimethoprim-sulfamethoxazole (TMS), penicillin G procaine (PGP), or a combination of TMS and PGP (control foals). Methods: Retrospective study. Methods: 143 foals < 240 days old. Methods: Information on age, sex, breed, primary drug treatment, total days of treatment with the primary drug, and whether the foal developed diarrhea, hyperthermia, or respiratory distress was obtained...
Towards an understanding of equine pleuropneumonia: factors relevant for control.
Australian veterinary journal    July 25, 2000   Volume 78, Issue 5 334-338 doi: 10.1111/j.1751-0813.2000.tb11788.x
Racklyeft DJ, Raidal S, Love DN.To review relevant literature on factors associated with the development of equine pleuropneumonia. Methods: A review of the literature using a range of databases including Current Contents, Medline, ChemAbstracts, Biological Abstracts and CAB and a comprehensive search strategy which involved use of keywords, author and subject category searches. Additional sources included review of articles cited by key accumulated references. Results: Since the early years of this century, many of the "gaps" in our knowledge of the pathogenesis of this disease have been filled. We now know that equine pleu...
Risk factors for equine influenza serum antibody titres in young thoroughbred racehorses given an inactivated vaccine.
Preventive veterinary medicine    July 6, 2000   Volume 46, Issue 2 129-141 doi: 10.1016/s0167-5877(00)00144-6
Newton JR, Lakhani KH, Wood JL, Baker DJ.Young Thoroughbred racehorses (222 yearlings entering training and 246 2-year-old horses already in training) from eight flat-training yards in Newmarket, UK were used to monitor serological responses to vaccination with an inactivated influenza virus vaccine. Blood samples taken prior to and after vaccination were tested by single radial haemolysis (SRH) to determine antibody titres (expressed as area of haemolysis in mm(2)). Prior to vaccination, yearlings had mean antibody titres (64+/-4 mm(2)) that were approximately half of those of 2-year-olds (115+/-3 mm(2)) and 89% of yearlings and 73%...
Foaling-management practices associated with the occurrence of enterocolitis attributed to Clostridium perfringens infection in the equine neonate.
Preventive veterinary medicine    June 16, 2000   Volume 46, Issue 1 61-74 doi: 10.1016/s0167-5877(00)00131-8
East LM, Dargatz DA, Traub-Dargatz JL, Savage CJ.Enterocolitis associated with Clostridium perfringens (C. perfringens) infection in neonatal foals is often severe and has been associated with a high case-mortality risk. We designed a premises-based survey to evaluate the associations of regional foaling practices, premises environmental management, periparturient foal and brood-mare management, and periparturient brood-mare ration with the occurrence of neonatal enterocolitis attributed to C. perfringens infection. Potential risk factors individually associated with enterocolitis were breed type, housing type at foaling and in the first thr...
Gait and speed as exercise components of risk factors associated with onset of fatigue injury of the third metacarpal bone in 2-year-old Thoroughbred racehorses.
American journal of veterinary research    June 13, 2000   Volume 61, Issue 6 602-608 doi: 10.2460/ajvr.2000.61.602
Boston RC, Nunamaker DM.To determine the degree to which components of the training program of 2-year-old Thoroughbred racehorses influence their susceptibility to fatigue injury of the third metacarpal bone (bucked shins). Methods: 226 two-year-old Thoroughbred racehorses. Methods: Daily training information and health reports on 2-year-old Thoroughbreds were compiled from records provided from 5 commercial stables. For each horse, data (exercise variables) were collected that comprised distance jogged (approx speed of 5 m/s), galloped (approx 11 m/s), and breezed (approx 15 to 16 m/s) until a single instance of buc...
Risk factors for enterolithiasis among horses in Texas.
Journal of the American Veterinary Medical Association    June 9, 2000   Volume 216, Issue 11 1787-1794 doi: 10.2460/javma.2000.216.1787
Cohen ND, Vontur CA, Rakestraw PC.To identify risk factors for enterolithiasis in horses. Methods: Matched case-control study. Methods: 26 horses with enteroliths, 104 horses with other causes of colic that underwent surgery (52 horses, surgical control group) or were treated medically (52 horses, nonsurgical control group). Methods: Medical records were reviewed for horses with enteroliths and control horses. Information collected included signalment, anamnesis, and findings on physical examination and clinicopathologic testing at admission. Horses with enteroliths and control horses were compared by means of conditional logi...
Association of high-speed exercise with racing injury in thoroughbreds.
Journal of the American Veterinary Medical Association    April 18, 2000   Volume 216, Issue 8 1273-1278 doi: 10.2460/javma.2000.216.1273
Cohen ND, Berry SM, Peloso JG, Mundy GD, Howard IC.To determine the association between high-speed exercise and risk of injury while racing among Thoroughbreds in Kentucky. Methods: Matched case-control study. Methods: 206 Thoroughbreds that sustained a musculoskeletal injury while racing and 412 Thoroughbreds that were not injured during the same races. Methods: Data regarding official timed workouts and races and the Beyer's numbers for the 3 races before the race during which injury occurred were extracted from past performance charts and compared between injured horses and control horses. Results: For injured horses, cumulative distance of...
Against all odds. Medical providers keep watch as jockeys bet their health on winning rides.
The Journal of the Arkansas Medical Society    April 13, 2000   Volume 96, Issue 10 366-369 
Turner L.No abstract available
The study of cutaneous melanomas in Camargue-type gray-skinned horses (2): epidemiological survey.
Pigment cell research    April 13, 2000   Volume 13, Issue 1 47-51 doi: 10.1034/j.1600-0749.2000.130109.x
Fleury C, Bérard F, Leblond A, Faure C, Ganem N, Thomas L.An epidemiological survey was made on cutaneous melanomas occurring in Camargue-type, gray-skinned horses in southern France. The population investigated was composed of 264 horses, which were selected from the Camargue horse stud registry and were allowed to be examined by the owners. The presence of tumors was inspected macroscopically according to the standardized protocols of veterinary medicine specialists, and some tumors were subjected to macroscopic histopathological examination. The results indicated that: 1) the prevalence of melanomas in the overall population was 31.4%; 2) the odds...
Jockey injuries in the United States.
JAMA    March 14, 2000   Volume 283, Issue 10 1326-1328 doi: 10.1001/jama.283.10.1326
Waller AE, Daniels JL, Weaver NL, Robinson P.In the sport of horse racing, the position of the jockey and speed of the horse predispose the jockey to risk of injury. Objective: To estimate rates of medically treated injuries among professional jockeys and identify patterns of injury events. Methods: Cross-sectional survey from data compiled by an insurance broker. Information on the cause of injury, location on the track, and body part injured was evaluated. Methods: Official races at US professional racing facilities (n = 114) from January 1, 1993, through December 31, 1996. Methods: A licensed jockey population of approximately 2700 pe...
Risk factors for disease associated with influenza virus infections during three epidemics in horses.
Journal of the American Veterinary Medical Association    February 25, 2000   Volume 216, Issue 4 545-550 doi: 10.2460/javma.2000.216.545
Morley PS, Townsend HG, Bogdan JR, Haines DM.To identify risk factors associated with respiratory tract disease in horses during 3 epidemics caused by influenza virus infections. Methods: Cross-sectional and prospective longitudinal observational studies. Methods: 1,163 horses stabled at a Thoroughbred racetrack. Methods: Investigations were conducted during a 3-year period. An epidemic of respiratory tract disease caused by influenza virus infections was identified in each year. Routine observations and physical examinations were used to classify horses' disease status. Data were analyzed to identify factors associated with development ...
Postmortem findings of gastric ulcers in Swedish horses older than age one year: a retrospective study of 3715 horses (1924-1996).
Equine veterinary journal    February 8, 2000   Volume 32, Issue 1 36-42 doi: 10.2746/042516400777612044
Sandin A, Skidell J, Häggström J, Nilsson G.The present study was performed to estimate retrospectively the prevalence of gastric ulceration in necropsied Swedish horses and to evaluate some potential risk factors. Horses (n = 3715) older than age one year and necropsied 1924-1996 were included. Information about breed, gender, age, season of death, clinical signs of colic, Gasterophilus larvae and documentation of diseases in different organs was recorded. Data on size, number and anatomical distribution of gastric ulcers were also obtained. The cold-blooded horses and the Standardbreds were the 2 most dominating breeds in our material...
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