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Topic:Treatment

Treatments for horses encompasses a range of medical and therapeutic interventions aimed at maintaining or restoring equine health. This field involves the use of pharmaceuticals, surgical procedures, and alternative therapies to address various conditions affecting horses. Common treatments include the administration of anti-inflammatory drugs, antibiotics, and vaccines, as well as physical therapies and nutritional management. Research in this area focuses on evaluating the efficacy, safety, and outcomes of different treatment modalities. This page collects peer-reviewed research studies and scholarly articles that explore the methods, advancements, and clinical outcomes associated with equine treatment practices.
Comparison of the use of scapular ultrasonography, physical examination, and measurement of serum biomarkers of bone turnover versus scintigraphy for detection of bone fragility syndrome in horses.
Journal of the American Veterinary Medical Association    December 14, 2012   Volume 242, Issue 1 76-85 doi: 10.2460/javma.242.1.76
Arens AM, Puchalski SM, Whitcomb MB, Bell R, Gardner IA, Stover SM.To define scintigraphic, physical examination, and scapular ultrasonographic findings consistent with bone fragility syndrome (BFS) in horses; develop indices of BFS severity; and assess accuracy of physical examination, scapular ultrasonography, and serum biomarkers for BFS diagnosis. Methods: Prospective case-control study. Methods: 48 horses (20 horses with BFS and 28 control horses). Methods: Horses underwent forelimb scintigraphic evaluation, physical examination, scapular ultrasonography, and serum collection. Scintigraphy was used as a reference standard to which physical examination, s...
Risk factors associated with cast complications in horses: 398 cases (1997-2006).
Journal of the American Veterinary Medical Association    December 14, 2012   Volume 242, Issue 1 93-98 doi: 10.2460/javma.242.1.93
Janicek JC, McClure SR, Lescun TB, Witte S, Schultz L, Whittal CR, Whitfield-Cargile C.To determine the frequency of and risk factors for complications associated with casts in horses. Methods: Multicenter retrospective case series. Methods: 398 horses with a half-limb or full-limb cast treated at 1 of 4 hospitals. Methods: Data collected from medical records included age, breed, sex, injury, limb affected, time from injury to hospital admission, surgical procedure performed, type of cast (bandage cast [BC; fiberglass tape applied over a bandage] or traditional cast [TC; fiberglass tape applied over polyurethane resin-impregnated foam]), limb position in cast (flexed, neutral, o...
Abdominal abscesses in adult horses: 61 cases (1993-2008).
Journal of the American Veterinary Medical Association    December 12, 2012   Volume 241, Issue 12 1659-1665 doi: 10.2460/javma.241.12.1659
Arnold CE, Chaffin MK.To determine clinical signs, diagnostic methods, treatment, and outcome for a series of adult horses with abdominal abscesses. Methods: Retrospective case series. Methods: 61 adult horses. Methods: Medical records of adult horses with abdominal abscesses treated at Texas A&M Veterinary Medical Teaching Hospital (1993 to 2008) were reviewed. Information was recorded regarding signalment, history, clinical signs, diagnosis, treatment, and short- and long-term outcomes. Risk factors for survival were determined. Results: 61 horses met the criteria for inclusion. Clinical signs included colic ...
Corneal stromal abscessation in two horses treated with intracorneal and subconjunctival injection of 1% voriconazole solution.
Veterinary ophthalmology    December 10, 2012   Volume 16, Issue 6 451-458 doi: 10.1111/vop.12014
Tsujita H, Plummer CE.To describe and evaluate intrastromal and subconjunctival injection of voriconazole for the therapy of deep corneal stromal abscess (DSA) in horses. Methods: A retrospective clinical study describing the indications for intrastromal and subconjunctival voriconazole injection and the outcomes of this procedure in two eyes of two horses. Methods: The two horses in this study failed to respond to medical therapy. Treatment with intracorneal and subconjunctival administration of 1% voriconazole was performed in this study. Results: Treatment with intracorneal and subconjunctival administration of ...
The effect of short- and long-term treatment with manuka honey on second intention healing of contaminated and noncontaminated wounds on the distal aspect of the forelimbs in horses.
Veterinary surgery : VS    December 5, 2012   Volume 42, Issue 2 154-160 doi: 10.1111/j.1532-950X.2012.01083.x
Bischofberger AS, Dart CM, Perkins NR, Kelly A, Jeffcott L, Dart AJ.To compare the effects of manuka honey and manuka honey gel on second intention healing of noncontaminated distal limb wounds and those contaminated with feces. Methods: Experimental study. Methods: Standardbred horses (n = 10). Methods: Five full-thickness wounds (2 × 2 cm) were created on both metacarpi. Wounds on 1 forelimb were covered with horse feces for 24 hours. Wounds on the contralateral limb were left uncontaminated. Wounds were assigned to the following 5 different treatments: manuka honey, manuka honey gel or gel applied for 12 days, manuka honey gel applied throughout healing an...
Advances in equine computed tomography and use of contrast media.
The Veterinary clinics of North America. Equine practice    November 28, 2012   Volume 28, Issue 3 563-581 doi: 10.1016/j.cveq.2012.08.002
Puchalski SM.Advances in equine computed tomography have been made as a result of improvements in software and hardware and an increasing body of knowledge. Contrast media can be administered intravascularly or intrathecally. Contrast media is useful to differentiate between tissues of similar density. Equine computed tomography can be used for many different clinical conditions, including lameness diagnosis, fracture identification and characterization, preoperative planning, and characterization of skull diseases.
The role of MRI in selected equine case management.
The Veterinary clinics of North America. Equine practice    November 28, 2012   Volume 28, Issue 3 647-658 doi: 10.1016/j.cveq.2012.08.006
Barrett MF, Frisbie DD.Magnetic resonance imaging (MRI) allows for excellent evaluation of many types of soft tissue and osseous lesions. Using MRI as a diagnostic modality can help in developing an individualized treatment protocol. Case management can include both surgical and medical intervention. Various MRI findings and associated treatment protocols are described.
Imaging of the equine proximal suspensory ligament.
The Veterinary clinics of North America. Equine practice    November 28, 2012   Volume 28, Issue 3 507-525 doi: 10.1016/j.cveq.2012.08.005
Werpy NM, Denoix JM.Injury to the suspensory ligament can result in significant lameness. Multiple imaging modalities may be required to fully characterize injury to the suspensory ligament. Ultrasonography of the suspensory ligament is challenging, due to the normal anatomy. This article describes imaging of the proximal suspensory ligament in the front and hind limbs of the horse.
Early detection of Trypanosoma evansi infection and monitoring of antibody levels by ELISA following treatment.
Journal of parasitic diseases : official organ of the Indian Society for Parasitology    November 20, 2012   Volume 38, Issue 1 124-127 doi: 10.1007/s12639-012-0204-2
Yadav SC, Kumar R, Manuja A, Goyal L, Gupta AK.In present communication, we report an outbreak of Trypanosoma evansi in equine herd n = 30 (horse and mules) which, were reared in fly proof stables as well as in open paddock maintained under semi-intensive system of management, and its effective control using trypanocidal drug. The infection was monitored by antibody ELISA up to 180 days post-treatment (PT). A total of 8 out of 14 equines (57.14 %) which were maintained only in open paddocks were found positive with T. evansi infection parasitologically. The infected animals were treated with quinapyramine methyl sulphate and chloride c...
Effect of butorphanol on thermal nociceptive threshold in healthy pony foals.
Equine veterinary journal    November 5, 2012   Volume 45, Issue 4 503-506 doi: 10.1111/j.2042-3306.2012.00673.x
McGowan KT, Elfenbein JR, Robertson SA, Sanchez LC.Pain management is an important component of foal nursing care, and no objective data currently exist regarding the analgesic efficacy of opioids in foals. Objective: To evaluate the somatic antinociceptive effects of 2 commonly used doses of intravenous (i.v.) butorphanol in healthy foals. Our hypothesis was that thermal nociceptive threshold would increase following i.v. butorphanol in a dose-dependent manner in both neonatal and older pony foals. Methods: Seven healthy neonatal pony foals (age 1-2 weeks), and 11 healthy older pony foals (age 4-8 weeks). Five foals were used during both age ...
Evaluation of growth models for follicle development and ovulation in Lusitano mares.
Animal reproduction science    November 1, 2012   Volume 136, Issue 1-2 81-84 doi: 10.1016/j.anireprosci.2012.10.026
Mata F.Several growth models are commonly used in the biological sciences, to model the follicle growth occurring in the estrous cycle. The aim of this project was to find the model that best fit the follicular size growth data for Lusitano mares. Retrospective data collected from reproduction book records of n=84 mares and n=124 cycles was used to find the series to be fitted to the models. The exponential, Gompertz, logistic, von Bertalanffy, Richards and Weibull models were used, and the most parsimonious and best fit was achieved with the logistic model (r(2)=0.999). The logistic model fits the L...
An approach to imaging algorithms for equine lameness diagnosis.
The Veterinary clinics of North America. Equine practice    November 1, 2012   Volume 28, Issue 3 467-481 doi: 10.1016/j.cveq.2012.08.007
Charles EM, Rantanen NW.Tremendous growth and advancement in equine diagnostic imaging necessitates a systematic approach to the application of these modalities to lameness diagnosis. This systematic approach must include attention to the history, physical and clinical examinations, and parameters set forth by the client. It also must include an understanding of which imaging modality is most appropriate given the details of the case. This article presents a basic framework with an underlying algorithmic foundation that can be applied when selecting imaging modalities during lameness evaluation and includes case exam...
Evaluation of motion correction processing in equine bone scintigraphy by Scheffé’s method of paired comparisons.
The Journal of veterinary medical science    October 23, 2012   Volume 75, Issue 3 369-371 doi: 10.1292/jvms.12-0127
Yamaguchi T, Endo Y, Nambo Y, Sato F, Sasaki N, Yamada K.Equine bone scintigraphy is usually performed with horses in standing position under sedation. However, swaying motion often leads to poor-quality images. To examine the usefulness of motion correction (MC) processing, equine bone scintigrams were evaluated using Scheffé's method of paired comparisons. A significant difference in evaluation scores was detected by analysis of variance (F test, P<0.01). According to all observers, Yardstick analysis scores were higher for images use of MC processing than for those no use of MC processing, for all parts. Overall scores of 5 observers were as ...
The effect of radio electric asymmetric conveyer treatment on sperm parameters of subfertile stallions: a pilot study.
Reproductive biology    October 22, 2012   Volume 12, Issue 3 277-284 doi: 10.1016/j.repbio.2012.09.007
Collodel G, Rinaldi S, Moretti E, Fontani V, Castagna A, Iacoponi F, Terzuoli G, C뻝u F, Careddu GM, Cossu I, Passino ES.The Radio Electric Asymmetric Conveyer (REAC) has been mostly applied to treat symptoms related to psychological stress. In the study, we demonstrated the effect of REAC-Veterinary Neuro Psycho Physical Optimization (VNPPO) treatment protocol on sperm parameters of subfertile (n=11) and fertile (n=4) stallions. Subfertile stallions showed a reduced sperm concentration, progressive motility and normal morphology compared to fertile stallions. An increase in progressive sperm motility and quality of sperm morphology was found in subfertile stallions after the REAC-VNPPO treatment. The positive e...
Growth and Development Symposium: Stem cell therapy in equine tendon injury.
Journal of animal science    October 16, 2012   Volume 91, Issue 1 59-65 doi: 10.2527/jas.2012-5736
Reed SA, Leahy ER.Tendon injuries affect all levels of athletic horses and represent a significant loss to the equine industry. Accumulation of microdamage within the tendon architecture leads to formation of core lesions. Traditional approaches to tendon repair are based on an initial period of rest to limit the inflammatory process followed by a controlled reloading program designed to promote the maturation and linear arrangement of scar tissue within the lesion. However, these treatment protocols are inefficient, resulting in prolonged recovery periods and frequent recurrence. Current alternative therapies ...
Stem cell therapy of tendinopathies: suggestions from veterinary medicine.
Muscles, ligaments and tendons journal    October 16, 2012   Volume 2, Issue 3 187-192 
Muttini A, Salini V, Valbonetti L, Abate M.The ideal strategy for tendon healing has not been identified to date. Recently, the use of stem cells based therapy has been proposed, due to their ability to proliferate and to differentiate towards specific connective tissues lineages. Embryonic stem cells should be considered the ideal cell source for regenerative therapies, but ethical factors limit their use in humans. Mesenchymal stem cells are more easily available and can be obtained by different sources. Amnion derived stem cells can differentiate towards all three germ layers, and can be used for allogeneic transplantation and store...
Bilateral parotid duct transposition for keratoconjunctivitis sicca in a Connemara stallion.
Veterinary ophthalmology    October 15, 2012   Volume 16, Issue 4 303-311 doi: 10.1111/j.1463-5224.2012.01068.x
Montgomery K, Ortved K, DeVries J, Hackett R, Kern T, Irby N, Ducharme N.A 7-year-old Connemara stallion was presented with a 4 month history of blepharospasm, recurrent corneal ulcerations, mucopurulent ocular discharge, and keratoconjunctivitis sicca (KCS) in both eyes unresponsive to medical therapy. Ophthalmic examination revealed lackluster corneas, axial corneal scarring and pigmentation with associated neovascularization, and absolute KCS in both eyes. Computed tomography scan and endoscopic evaluation of the upper airway and guttural pouches revealed no structural abnormalities to indicate neurogenic KCS. The stallion was diagnosed with immune-mediated dacr...
Ultrasound-guided retrobulbar nerve block in horses: a cadaveric study.
Veterinary anaesthesia and analgesia    October 11, 2012   Volume 40, Issue 2 205-211 doi: 10.1111/j.1467-2995.2012.00780.x
Morath U, Luyet C, Spadavecchia C, Stoffel MH, Hatch GM.To develop an ultrasound-guided technique for retrobulbar nerve block in horses, and to compare the distribution of three different volumes of injected contrast medium (CM) (4, 8 and 12 mL), with the hypothesis that successful placement of the needle within the retractor bulbi muscle cone would lead to the most effective dispersal of CM towards the nerves leaving the orbital fissure. Methods: Prospective experimental cadaver study. Methods: Twenty equine cadavers. Methods: Ultrasound-guided retrobulbar injections were performed in 40 cadaver orbits. Ultrasound visualization of needle placement...
Ultrasonographic visualization of colonic mesenteric vasculature as an indicator of large colon right dorsal displacement or 180° volvulus (or both) in horses.
The Canadian veterinary journal = La revue veterinaire canadienne    October 2, 2012   Volume 53, Issue 4 378-382 
Ness SL, Bain FT, Zantingh AJ, Gaughan EM, Story MR, Nydam DV, Divers TJ.Visualization of colonic mesenteric vasculature during transabdominal ultrasonographic examination of horses with colic can be a predictor of right dorsal displacement of the large colon or 180° large colon volvulus, or both. Medical records of 82 horses having had surgical treatment of colic and having received a transabdominal ultrasonographic examination on admission were reviewed. Colonic mesenteric vessels were sonographically identified coursing laterally on the right side of the abdomen in 24 of the 82 cases. Horses with colonic vessels identified on ultrasound were 32.5 times more lik...
Farriery for hoof wall defects: quarter cracks and toe cracks.
The Veterinary clinics of North America. Equine practice    September 18, 2012   Volume 28, Issue 2 393-406 doi: 10.1016/j.cveq.2012.06.005
Pleasant RS, O'Grady SE, McKinlay I.Conditions that result in the loss of the structural integrity of the hoof wall, such as quarter and toe cracks, are not uncommon and usually manifest in lameness. The successful management of these problems involves identifying and addressing the underlying causes, stabilization of the foot, and committed follow-up.
Therapeutic farriery.
The Veterinary clinics of North America. Equine practice    September 18, 2012   Volume 28, Issue 2 xi-xii doi: 10.1016/j.cveq.2012.06.009
Moyer WA.No abstract available
Farriery for the hoof with low or underrun heels.
The Veterinary clinics of North America. Equine practice    September 18, 2012   Volume 28, Issue 2 351-364 doi: 10.1016/j.cveq.2012.06.002
Hunt RJ.Underrun heels are common and involve hoof capsule distortion in which the horn tubules of the heels undergo bending and lengthening, resulting in decreased strength and functionality. The syndrome varies in clinical presentation, depending on duration, severity of distortion, presence of secondary problems, and presence of lameness. Primary treatment goals are to maintain soundness and functional integrity of the foot and to establish a normal hoof capsule. Resolution of the problem is generally not achieved in horses in a heavy work schedule, and realistic goals in this situation are to main...
Equine keratomycoses in California from 1987 to 2010 (47 cases).
Equine veterinary journal    September 4, 2012   Volume 45, Issue 3 361-366 doi: 10.1111/j.2042-3306.2012.00623.x
Reed Z, Thomasy SM, Good KL, Maggs DJ, Magdesian KG, Pusterla N, Hollingsworth SR.Equine keratomycosis in the western USA has received little study, probably owing to its low prevalence. Objective: To determine clinical features, predominant fungal isolates, treatment modalities and outcomes of horses with keratomycosis in California and compare these with results from different geographic regions. Methods: Records of horses presented to the University of California-Davis Veterinary Medical Teaching Hospital (UCD-VMTH) with confirmed keratomycosis between 1987 and 2010 were reviewed for this retrospective study. Information retrieved from the record included background, oph...
A natural progression: Equine dentistry at the University of Minnesota Veterinary Medical Center.
Northwest dentistry    August 30, 2012   Volume 91, Issue 4 14-18 
Goldstein G, Wefel S.No abstract available
Evaluation of a diode laser for use in induction of tendinopathy in the superficial digital flexor tendon of horses.
American journal of veterinary research    August 29, 2012   Volume 73, Issue 9 1435-1444 doi: 10.2460/ajvr.73.9.1435
Vallance SA, Vidal MA, Whitcomb MB, Murphy BG, Spriet M, Galuppo LD.To evaluate use of a diode laser to induce tendinopathy in the superficial digital flexor tendon (SDFT) of horses. Methods: 4 equine cadavers and 5 adult horses. Methods: Cadaveric SDFT samples were exposed to a diode laser at various energy settings to determine an appropriate energy for use in in vivo experiments; lesion size was assessed histologically. In vivo experiments involved laser energy induction of lesions in the SDFT (2 preliminary horses [0, 25, 75, and 87.5 J] and 3 study horses [0 and 125 J]) and assessment of lesions. Study duration was 21 days, and lesions were assessed clini...
The isolated perfused equine distal limb as an ex vivo model for pharmacokinetic studies.
Journal of veterinary pharmacology and therapeutics    August 23, 2012   Volume 36, Issue 3 292-297 doi: 10.1111/jvp.12001
Friebe M, Stahl J, Kietzmann M.Even though intra-articular injections play an important role in the treatment of joint-related lameness in horses, little is known about pharmacokinetic properties of substances used. Therefore, an ex vivo model for pharmacokinetic studies was developed using distal forelimbs of slaughtered horses. The extremity was perfused with gassed Tyrode solution for up to 8 h. Tissue viability was confirmed by measurements of glucose consumption, lactate production, and lactate dehydrogenase activity in the perfusate. Standard criteria for tissue viability had been determined in preliminary experiments...
Pharmacokinetic analysis of topical tobramycin in equine tears by automated immunoassay.
BMC veterinary research    August 21, 2012   Volume 8 141 doi: 10.1186/1746-6148-8-141
Czerwinski SL, Lyon AW, Skorobohach B, Léguillette R.Ophthalmic antibiotic therapy in large animals is often used empirically because of the lack of pharmacokinetics studies. The purpose of the study was to determine the pharmacokinetics of topical tobramycin 0.3% ophthalmic solution in the tears of normal horses using an automated immunoassay analysis. Results: The mean tobramycin concentrations in the tears at 5, 10, 15, 30 minutes and 1, 2, 4, 6 hours after administration were 759 (±414), 489 (±237), 346 (±227), 147 (±264), 27.6 (±28.4), 14.8 (±66.6), 6.7 (±18.6), and 23.4 (±73.4) mg/L. Mean tobramycin concentration was maintained abo...
Successful therapeutic management of concurrent subclinical Eimeria leukarti and Babesia (Theileria) equi infection in a mare.
Journal of parasitic diseases : official organ of the Indian Society for Parasitology    August 17, 2012   Volume 37, Issue 2 177-180 doi: 10.1007/s12639-012-0156-6
Sudan V, Sharma RL, Gupta SR, Borah MK.The occurrence of Eimeria leukarti infection in equine is being sporadically documented despite its cosmopolitan prevalence. A Marwari mare, aged 3 years and 6 months and owned by a socio-economically weaker class of labourer of royal families, was suffering from non specific enteric disorders. Detailed systemic clinical examination of mare confirmed subclinical enteric infection with E. leukarti and piroplasms of Babesia (Theileria) equi in the circulating erythrocytes. She was therapeutically managed with synchronous administration of specific and supportive therapy with success. Non speci...
Does firing have a valid place in the treatment of superficial digital flexor tendon injury in the 21st century?
Equine veterinary journal    August 15, 2012   Volume 44, Issue 5 509-510 doi: 10.1111/j.2042-3306.2012.00642.x
Marr CM, Bowen IM.No abstract available
Efficacy of domperidone gel in an induced model of fescue toxicosis in periparturient mares.
Theriogenology    August 13, 2012   Volume 78, Issue 6 1361-1370 doi: 10.1016/j.theriogenology.2012.06.002
Cross DL, Reinemeyer CR, Prado JC, Donnell RL, Bond KG, Farr H, Longhofer SL.The objective was to evaluate the efficacy of domperidone in the prevention of reproductive complications of fescue toxicosis in periparturient mares. Pregnant mares at ≤310 days of gestation were fed ≥200 μg ergovaline per kg diet daily in endophyte-infected fescue hay and seed, starting ≥30 days before their expected foaling date (EFD: 340 days after breeding). Thirty-five mares were randomized to a treatment group to receive either domperidone gel (n = 20, 1.1 mg/kg, PO, once daily) or placebo (n = 15). Treatment was initiated 10 to 15 days before the EFD and continued for 5 days aft...
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