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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Surgical treatment of cervical stenotic myelopathy in horses: 73 cases (1983-1992).
Journal of the American Veterinary Medical Association    July 1, 1993   Volume 203, Issue 1 108-112 
Moore BR, Reed SM, Robertson JT.Seventy-three horses with cervical stenotic myelopathy underwent cervical vertebral interbody fusion (n = 63) or dorsal laminectomy (n = 10). Neurologic function improved in 77% of horses, and 46% of horses achieved athletic function (racing, race training, or pleasure riding) after cervical vertebral interbody fusion for static and dynamic spinal cord compressive lesions. Neurologic status improved in 4 of 10 horses after dorsal decompression for static compressive spinal cord lesions. The duration of clinical signs prior to surgical intervention was shorter for horses that achieved athletic ...
Phenytoin increases specific triacylglycerol fatty esters in skeletal muscle from horses with hyperkalemic periodic paralysis.
Biochimica et biophysica acta    July 1, 1993   Volume 1168, Issue 3 292-298 doi: 10.1016/0005-2760(93)90185-c
Fletcher JE, Erwin K, Beech J.Previous studies have demonstrated that phenytoin decreases the levels of triacylglycerols in several tissues other than skeletal muscle. Since phenytoin is clinically effective in several skeletal muscle disorders, triacylglycerol metabolism in skeletal muscle from four normal Quarter horses and four Quarter horses with hyperkalemic periodic paralysis was examined. The horses with hyperkalemic periodic paralysis had low levels of 18:3 in the phospholipids, low levels of 16:0, 16:1 and 18:3 in the free fatty acids and low levels of 20:4 in triacylglycerols. Triacylglycerol levels were increase...
Streptococci and Pasteurella spp. associated with disease of the equine lower respiratory tract.
Equine veterinary journal    July 1, 1993   Volume 25, Issue 4 314-318 doi: 10.1111/j.2042-3306.1993.tb02970.x
Wood JL, Burrell MH, Roberts CA, Chanter N, Shaw Y.The likelihood of finding evidence of inflammation in 551 tracheal washes collected endoscopically from 278 Thoroughbred racehorses increased with the number of bacterial colony forming units (cfu) per ml of wash (P < 0.001). The aerobic bacteria Streptococcus zooepidemicus, Pasteurella/Actinobacillus-like species and Streptococcus pneumoniae were significantly associated with lower airway inflammation whereas coagulase-negative Staphylococcus spp., alpha-haemolytic Streptococcus spp., Acinetobacter spp., Bacillus spp., Escherichia coli, Pseudomonas aeruginosa, non-haemolytic Streptococcus spp...
Correction of patellar luxation by recession sulcoplasty in three foals.
Veterinary surgery : VS    July 1, 1993   Volume 22, Issue 4 298-300 doi: 10.1111/j.1532-950x.1993.tb00402.x
Kobluk CN.Lateral luxation of the patella in four femoropatellar joints of three foals was repaired by recession sulcoplasty and medial imbrication of the joint. One foal was euthanatized because of septic arthritis caused by incisional dehiscence, and the other two foals were normal 2 years after surgery. Recession sulcoplasty combined with medial imbrication of the joint capsule resulted in a functional femoropatellar joint and should be considered in foals affected with lateral patellar luxation.
Import of horses from Europe: an insect-proof container.
Australian veterinary journal    July 1, 1993   Volume 70, Issue 7 277-278 
Doyle KA.No abstract available
In vivo investigation of communication between the distal intertarsal and tarsometatarsal joints in horses and ponies.
Veterinary surgery : VS    July 1, 1993   Volume 22, Issue 4 289-292 doi: 10.1111/j.1532-950x.1993.tb00400.x
Bell BT, Baker GJ, Foreman JH, Abbott LC.The frequency of communication between the tarsometatarsal and distal intertarsal joints was investigated in 27 horses and 12 ponies. After the injection of diluted latex into the tarsometatarsal joints using the plantarolateral approach, the horses and ponies were walked for 200 meters. Latex was found in the distal intertarsal joints of 19 of 73 tarsi (26% communication) at necropsy. In 3 tarsi, latex was also found in the proximal intertarsal and tarsocrural joints.
Development of neutralizing antibody in horses infected with Ehrlichia risticii.
Veterinary microbiology    July 1, 1993   Volume 36, Issue 1-2 139-147 doi: 10.1016/0378-1135(93)90135-t
Rikihisa Y, Wada R, Reed SM, Yamamoto S.The role of the humoral immune response in ehrlichial infection is unknown. Development of neutralizing antibodies during a course of Ehrlichia risticii infection in a pony was examined in vitro by determining the inhibition of E. risticii infection of P388D1 cells in the presence of the sera. The pony experimentally infected with E. risticii developed significant neutralizing activity in the sera by 15 days postinfection when parasitemia started to decline. Neutralizing activity continued to rise after recovery from the disease up to 34 days postinfection at which time the experiment was term...
Development to blastocysts of one- to two-cell equine embryos after coculture with uterine tubal epithelial cells.
American journal of veterinary research    July 1, 1993   Volume 54, Issue 7 1139-1144 
Ball BA, Brinsko SP, Thomas PG, Miller PG, Ellington JE.Development of 1- to 2-cell in vivo fertilized equine embryos cultured with or without uterine tubal epithelial cells (UTEC) was studied. One- to 2-cell embryos (n = 26) were collected surgically from the uterine tubes of pony mares 1 day after ovulation. Four- to 8-cell embryos (n = 9) were collected 2 days after ovulation. Presumptive zygotes and 2-cell embryos were cultured with (n = 17) or without (n = 9) UTEC, and all 4- to 8-cell embryos were cocultured with UTEC as positive controls. Uterine tubal epithelial cells were used as cell suspensions within 2 weeks after initiation of cultures...
Effect of polysulfated glycosaminoglycan on osteoarthritic equine articular cartilage in explant culture.
American journal of veterinary research    July 1, 1993   Volume 54, Issue 7 1116-1121 
Caron JP, Toppin DS, Block JA.Middle carpal cartilage explants from 4 horses with mild osteoarthritis involving that joint were maintained in tissue culture to test the effects of a polysulfated glycosaminoglycan (PSGAG) on proteoglycan synthesis and degradation. Cultures were exposed to 0.025 or 25 mg of PSGAG/ml for 48 hours, after which the medium was replaced with medium containing similar doses of PSGAG and 35S. Subsequently, the sulfated proteoglycan content of the medium and extracts of the explants was measured. Gel filtration chromatography was used to estimate the size and to purify the principal, large proteogly...
Examination of frozen cross sections of cervical spinal intersegments in nine horses with cervical vertebral malformation: lesions associated with spinal cord compression. Trostle SS, Dubielzig RR, Beck KA.Nine horses with clinical and radiographic findings of cervical vertebral malformation that were necropsied and examined using frozen cervical spinal cord cross sections were reviewed. Only cases with actual distortion of the spinal cord due to compression were selected. The goal of the study was to determine the morphologic features responsible for narrowing of the spinal canal and compression of the spinal cord. In individual cases, bony changes are associated with osteochondrosis and osteomyelitis of the dorsal articular facets and osteosclerosis of the dorsal cervical lamina. Soft tissue p...
What is your diagnosis? Congenital fusion of vertebrae C1 and C2.
Journal of the American Veterinary Medical Association    July 1, 1993   Volume 203, Issue 1 47-48 
Vatistas N, Lee M, Snyder J.No abstract available
Cardiovascular effects of thoracic compression in horses subjected to euthanasia.
Equine veterinary journal    July 1, 1993   Volume 25, Issue 4 282-284 doi: 10.1111/j.2042-3306.1993.tb02964.x
Hubbell JA, Muir WW, Gaynor JS.Six horses scheduled for euthanasia were instrumented for the measurement of blood flow by thermodilution, pulmonary arterial, right atrial and arterial blood pressures and collection of arterial blood for pH and blood gas analysis. The horses were anaesthetised with intravenous (iv) thiamylal sodium (10 mg/kg) and placed in right lateral recumbency. After euthanasia with an overdose of pentobarbitone sodium (100 mg/kg, iv) and loss of the electrocardiogram and arterial pulse pressure, thoracic compression at rates of 40, 60 and 80 compressions/min was instituted. Thoracic compression was acco...
Use of scintimetry to assess effects of exercise and polysulfated glycosaminoglycan on equine carpal joints with osteochondral defects.
American journal of veterinary research    July 1, 1993   Volume 54, Issue 7 997-1006 
Todhunter RJ, Altman NS, Kallfelz FA, Nersesian P, Lust G.Combined blood pool and delayed images produced by use of 99mTc-methylene diphosphonate (99mTcMDP) were evaluated as an objective measurement of the response of equine joints with osteochondral defects to postoperative exercise and intra-articularly administered polysulfated glycosaminoglycan (PSGAG). Osteochondral defects (approx 2.4 x 0.9 cm) were induced arthroscopically in the dorsodistal radial carpal bones of 18 ponies. These ponies were randomized (while balancing for age [range 2 to 15; median, 5.0; mean, 5.1 years]) to 2 treatment groups. Nine ponies were assigned to be exercised, and...
Ovarian follicles, ovulations and progesterone concentrations in aged versus young mares.
Theriogenology    July 1, 1993   Volume 40, Issue 1 21-32 doi: 10.1016/0093-691x(93)90338-6
Vanderwall DK, Woods GL, Freeman DA, Weber JA, Rock RW, Tester DF.The objectives of this study were: 1) to document age-related ovulation failure in mares and 2) to contrast the number of ovarian follicles, occurrence of ovulations, and postovulatory concentrations of progesterone in aged versus young mares. In Experiment 1, 4 of 10 aged (25- to 33-years-old) mares were anovulatory between July 1 and September 1, 1989. In Experiment 2, two of 25 aged (20- to 30-years-old) and none of 21 young (3- to 12-years-old) mares were anovulatory between February 1 and June 30, 1990. The average (+/- SEM) day of the first ovulation was later (P<0.05) for aged versus...
Urinary indices of horses after intravenous administration of crystalloid solutions.
Journal of veterinary internal medicine    July 1, 1993   Volume 7, Issue 4 241-246 doi: 10.1111/j.1939-1676.1993.tb01014.x
Roussel AJ, Cohen ND, Ruoff WW, Brumbaugh GW, Schmitz DG, Kuesis BS.Saline or glucose solution was infused for approximately 4 hours into six healthy mares in two separate experiments to determine the effect of infusion of crystalloid solutions on fractional excretion (FE) of sodium (Na), chloride (Cl), potassium (K), and phosphorus (P), ratio of urinary creatinine to serum creatinine (UCr/SCr), and ratio of urinary osmolality to serum osmolality (Uosm/Sosm). After intravenous infusion of either saline or glucose solution, FENa, FECl and FEP were significantly increased, whereas UCr/SCr and Uosm/Sosm were significantly decreased. In addition, FEK was significa...
Ventral meningomyelocoele in a filly.
Journal of comparative pathology    July 1, 1993   Volume 109, Issue 1 93-97 doi: 10.1016/s0021-9975(08)80244-7
Harmelin A, Egozi O, Nyska A, Perel S, Yakobson B, Orgad U, Waner T.No abstract available
Validation of an acrosomal stain for equine sperm that differentiates between living and dead sperm.
Journal of andrology    July 1, 1993   Volume 14, Issue 4 289-297 
Casey PJ, Hillman RB, Robertson KR, Yudin AI, Liu IK, Drobnis EZ.An acrosomal staining technique that can differentiate between living and dead sperm was developed for equine sperm. The fluoresceinated lectin Pisum sativum agglutinin (FITC-PSA) was used to identify the presence or absence of acrosomal contents, while the supravital nuclear dye Hoechst 33258 (H258) was used to assess viability. The accuracy of the FITC-PSA acrosomal stain was tested by comparing the percentage of sperm that had lost their acrosomal contents, detected by the staining method, with that detected by transmission electron microscopy (TEM). Following capacitation in vitro, the acr...
Neutrophil chemotaxis in the horse is not mediated by a complex of equine neutrophil elastase and equine alpha-1-proteinase inhibitor.
The British veterinary journal    July 1, 1993   Volume 149, Issue 4 331-338 doi: 10.1016/S0007-1935(05)80074-0
Scudamore CL, Pemberton A, Watson ED, Miller HR.Studies have demonstrated that as a result of proteolytic inactivation or complex formation (with neutrophil elastase), human alpha-1-proteinase inhibitor (API) becomes a potent chemoattractant for human neutrophils. The present study aimed to investigate the in vitro chemotactic response of equine neutrophils to an equivalent complex of equine API and neutrophil elastase. No evidence of neutrophil migration was observed towards purified complex derived from equine neutrophil elastase and the Spi 1 isoform of equine API, or to crude mixtures of porcine pancreatic elastase and unseparated equin...
Hepatic lobe torsion as a cause of colic in a horse.
Veterinary surgery : VS    July 1, 1993   Volume 22, Issue 4 301-304 doi: 10.1111/j.1532-950x.1993.tb00403.x
Turner TA, Brown CA, Wilson JH, Roth L, Rosenstein DS, Schweizer CM, Woodaman KA.A 14-year-old Arabian gelding was examined for colic. An exploratory celiotomy was subsequently performed and the left lobe of the liver was found to be twisted. The lobe was resected using a TA-90 surgical stapling instrument. Histologic examination of the resected liver indicated portal vein and sinusoid dilation and congestion with blood. There were focal areas of necrosis and bacterial cocci and rods throughout the section. The histologic findings were consistent with hepatic lobe torsion. After surgery, the horse was treated with broad spectrum antibiotics, anti-inflammatory drugs, hepari...
Equine viral arteritis–a challenge for the British horse industry.
The British veterinary journal    July 1, 1993   Volume 149, Issue 4 305-306 doi: 10.1016/S0007-1935(05)80247-7
Higgins AJ.No abstract available
Potassium concentrations in muscle, plasma and erythrocytes and urinary fractional excretion in normal horses and those with chronic intermittent exercise-associated rhabdomyolysis.
Research in veterinary science    July 1, 1993   Volume 55, Issue 1 43-51 doi: 10.1016/0034-5288(93)90032-b
Beech J, Lindborg S, Braund KG.Potassium concentrations were measured in semimembranosus muscle, plasma and erythrocytes, and the urinary fractional excretion determined in normal horses and those that had chronic intermittent exercise-associated rhabdomyolysis. Muscle from the rhabdomyolysis horses was also evaluated microscopically. The horses with rhabdomyolysis had a lower muscle potassium concentration on a dry weight basis. Although the wet weight potassium content was also lower, the difference was not significant. Urinary fractional excretion of potassium (and also sodium and chloride) did not differ significantly b...
Partial re-establishment of villous placentation after reduction of an equine co-twin by foetal cardiac puncture.
Equine veterinary journal    July 1, 1993   Volume 25, Issue 4 336-338 doi: 10.1111/j.2042-3306.1993.tb02977.x
Ball BA, Schlafer DH, Card CE, Yeager AE.No abstract available
The role of vascular mechanisms in the development of acute equine laminitis.
Journal of veterinary internal medicine    July 1, 1993   Volume 7, Issue 4 228-234 doi: 10.1111/j.1939-1676.1993.tb01012.x
Hood DM, Grosenbaugh DA, Mostafa MB, Morgan SJ, Thomas BC.No abstract available
Evaluation of local endobronchial antigen challenges in the investigation of equine chronic obstructive pulmonary disease.
Equine veterinary journal    July 1, 1993   Volume 25, Issue 4 269-272 doi: 10.1111/j.2042-3306.1993.tb02961.x
McGorum BC, Dixon PM.Local transendoscopic endobronchial antigen challenge, which has proved to be a valuable clinical and research technique in the study of human pulmonary hypersensitivity, was evaluated in control and asymptomatic COPD--affected horses. Transendoscopic endobronchial challenges with phosphate-buffered saline (PBS), Micropolyspora faeni extract at 60 and 600 micrograms/ml and mouldy hay extract elicited neutrophilic airway inflammatory responses in control (N = 5-7) and asymptomatic COPD-affected (N = 5-7) horses, as determined by cytological examinations of bronchoalveolar lavage fluid (BALF) ha...
Circulation of eastern equine encephalitis, western equine encephalitis, Ilhéus, Maguari and Tacaiuma viruses in equines of the Brazilian Pantanal, South America.
Revista do Instituto de Medicina Tropical de Sao Paulo    July 1, 1993   Volume 35, Issue 4 355-359 doi: 10.1590/s0036-46651993000400009
Iversson LB, Silva RA, da Rosa AP, Barros VL.Neutralizing antibodies to EEE (6.7%), WEE (1.2%), ILH (26.6%), MAG (28.2%) and TCM (15.7%) viruses were found in sera of 432 equines of the Brazilian Pantanal, area where undiagnosed horse deaths are frequently observed. A 4-fold rise in CF titer to EEE virus was detected in acute and convalescent sera of an encephalitis horse sacrificed in 1992. Antibodies to EEE, ILH, MAG and TCM viruses were detected in horses less than 2 years old indicating recent circulation of these viruses in the Pantanal. The evidence of recent equine encephalitis associated with rising CF titer to EEE warrants a mor...
Botryoid rhabdomyosarcoma of the urinary bladder in a filly. Turnquist SE, Pace LW, Keegan K, Andrews-Jones L, Kreeger JM, Bailey KL, Stogsdill PL, Wilson HA.No abstract available
Correlations between ultrasonography findings and hormonal profiles at oestrus in pure Spanish breed mares.
Australian veterinary journal    July 1, 1993   Volume 70, Issue 7 273-275 doi: 10.1111/j.1751-0813.1993.tb08054.x
Illera JC, Illera MJ, Silvan G, Illera M.No abstract available
Persistent hyperbilirubinemia in a healthy thoroughbred horse.
The Cornell veterinarian    July 1, 1993   Volume 83, Issue 3 237-242 
Divers TJ, Schappel KA, Sweeney RW, Tennant BC.Persistent hyperbilirubinemia and icterus are described in a healthy 4-year-old Thoroughbred horse. Hyperbilirubinemia was not related to food intake and was not associated with evidence of increased hemolysis or with acquired hepatic disease. The hyperbilirubinemia was thought to be a result of inappropriate conjugation of bilirubin rather than any abnormality in bilirubin uptake or excretion. The bilirubinemia in this horse appears most similar to a human syndrome, caused by a familial deficiency of bilirubin-uridine diphosphate glucuronyl transferase.
Relationship between onset of puberty and establishment of persistent infection with equine arteritis virus in the experimentally infected colt.
Journal of comparative pathology    July 1, 1993   Volume 109, Issue 1 29-46 doi: 10.1016/s0021-9975(08)80238-1
Holyoak GR, Little TV, McCollam WH, Timoney PJ.The relationship between stage of reproductive tract maturity and susceptibility to the experimental establishment of persistent infection with equine arteritis virus (EAV) was investigated in 21 prepubertal and 15 peripubertal colts. Five of six prepubertal colts inoculated intranasally remained infected in the reproductive tract from post-challenge day 28 to 93 and two of six from post-challenge day 120 to 180. No virus was detected in five of these animals killed on post-challenge day 210. Each of two peripubertal colts remained infected in the reproductive tract at post-challenge day 60 an...
Effects of sample collection and handling on concentration of osteocalcin in equine serum.
American journal of veterinary research    July 1, 1993   Volume 54, Issue 7 1017-1020 
Hope E, Johnston SD, Hegstad RL, Geor RJ, Murphy MJ.A commercially available radioimmunoassay kit for measurement of human osteocalcin was validated for use in horses. For accurate measurement of equine serum osteocalcin, blood samples may be collected at a temperature between 20 and 25 C, then centrifuged within 90 minutes; serum may be stored at -20 C in plastic tubes for up to 26 weeks. Serum may be thawed and refrozen up to 5 times without significant change in measured equine serum osteocalcin concentration. Assay sensitivity was 0.16 ng/ml. Recovery of bovine osteocalcin standard added to equine serum was linear. Intra-assay coefficient o...