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Topic:Veterinary Practice

Veterinary practice in relation to horses encompasses the medical care, management, and treatment of equine species. This field involves various aspects of equine health, including preventive care, diagnosis, and treatment of diseases, surgical interventions, and emergency care. Equine veterinarians employ a range of diagnostic tools and techniques such as physical examinations, imaging, and laboratory tests to assess and monitor horse health. In addition to addressing physical ailments, veterinary practice also includes nutritional management, reproductive health, and performance-related issues. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, advancements, and outcomes in veterinary practices specific to equine health.
Effect of butorphanol, midazolam or ketamine on romifidine based sedation in horses during standing cheek tooth removal.
BMC veterinary research    December 6, 2017   Volume 13, Issue 1 381 doi: 10.1186/s12917-017-1299-6
Müller TM, Hopster K, Bienert-Zeit A, Rohn K, Kästner SBR.Standing surgery, especially dental procedures, are commonly performed in horses. This leads to an increasing demand for reliable sedation protocols. Therefore, it was the purpose of this study to investigate the influence of butorphanol, midazolam or ketamine on romifidine based sedation in horses during cheek tooth removal. Methods: Forty horses presented for tooth extraction were divided in four groups using matched pair randomization. Group R was sedated with romifidine (bolus 0.03 mg/kg, followed by a constant rate infusion (CRI) 0.05 mg/kg/h) and group RB with romifidine (same dose) an...
Veterinary Medical Ethics.
The Canadian veterinary journal = La revue veterinaire canadienne    December 6, 2017   Volume 58, Issue 12 1253-1255 
Rollin BE.No abstract available
Detection and confirmation of α-cobratoxin in equine plasma by solid-phase extraction and liquid chromatography coupled to mass spectrometry.
Journal of chromatography. A    December 6, 2017   Volume 1533 38-48 doi: 10.1016/j.chroma.2017.12.010
Guan F, You Y, Li X, Robinson MA.α-Cobratoxin (CTX) is a large peptide (71 amino acids) with strong analgesic effect and may be misused in sports such as horse racing. To prevent such misuse, a sensitive method is required for detection and confirmation of the toxin in equine samples. CTX was extracted from equine plasma using an optimized mixed-mode solid-phase extraction (SPE) procedure. Extracted CTX was reduced with dithiothreitol and alkylated with iodoacetamide, and then was digested by trypsin at 56°C for 30min. The digest was analysed by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS), and trypt...
Development of a clinical prediction score for detection of suspected cases of equine grass sickness (dysautonomia) in France.
Veterinary research communications    December 4, 2017   Volume 42, Issue 1 19-27 doi: 10.1007/s11259-017-9704-y
Randleff-Rasmussen PK, Leblond A, Cappelle J, Bontemps J, Belluco S, Popoff MR, Marcillaud-Pitel C, Tapprest J, Tritz P, Desjardins I.Equine grass sickness (EGS) (equine dysautonomia) is a neurodegenerative condition of grazing equines. Pre-mortem diagnosis of EGS is a challenge for practitioners as definitive diagnosis requires ileal/myenteric lymph node biopsies. This study aimed to develop a clinical score that could be used by practitioners to improve the detection of acute or subacute EGS cases in the field. Suspected EGS cases were declared by veterinary practitioners. A case was classified as confirmed positive if ileal or rectal biopsy samples showed neuronal degeneration typical of EGS. A semi-quantitative scoring s...
Vessel sealer and divider instrument temperature during laparoscopic ovariectomy in horses.
Veterinary surgery : VS    December 3, 2017   Volume 47, Issue S1 O26-O31 doi: 10.1111/vsu.12755
Easley JT, McGilvray KC, Hendrickson DA, Bruemmer J, Hackett ES.To determine the temperature of a vessel sealer and divider device during unilateral paralumbar laparoscopic ovariectomy in standing, sedated mares. Methods: Prospective study. Methods: Fifteen healthy research mares. Methods: Healthy mares with normal ovarian palpation and ultrasonographic appearance were enrolled. Horses were restrained in standing stocks and sedated. A right or left paralumbar ovariectomy was performed with a laparoscopic portal and 2 instrument portals. Ovaries were excised with traumatic forceps and a blunt tip vessel sealer and divider. Temperatures of the vessel sealer ...
Effects of transdermal lidocaine or lidocaine with prilocaine or tetracaine on mechanical superficial sensation and nociceptive thermal thresholds in horses.
Veterinary anaesthesia and analgesia    December 2, 2017   Volume 45, Issue 2 227-233 doi: 10.1016/j.vaa.2017.10.003
Söbbeler FJ, Kästner SB.To evaluate the transdermal local anaesthetic effect of lidocaine or lidocaine combined with prilocaine or tetracaine in horses. Methods: Experimental, randomized study. Methods: A total of five healthy adult warmblood horses. Methods: Horses were clipped bilaterally at the withers, cranial saddle area and caudal saddle area. Baseline measurements for mechanical superficial sensation via von Frey filaments and nociceptive thermal thresholds were performed. A 5% lidocaine patch (12 hour exposure, treatment L), a lidocaine/prilocaine cream (each 2.5%, treatment LP) and a lidocaine/tetracaine cre...
Retrospective evaluation of correlation and agreement between two recovery scoring systems in horses.
The Veterinary record    December 1, 2017   Volume 182, Issue 6 169 doi: 10.1136/vr.104546
Scarabelli S, Rioja E.No abstract available
Adverse Reactions to Vaccination: From Anaphylaxis to Autoimmunity.
The Veterinary clinics of North America. Small animal practice    November 29, 2017   Volume 48, Issue 2 279-290 doi: 10.1016/j.cvsm.2017.10.005
Gershwin LJ.Vaccines are important for providing protection from infectious diseases. Vaccination initiates a process that stimulates development of a robust and long-lived immune response to the disease agents in the vaccine. Side effects are sometimes associated with vaccination. These vary from development of acute hypersensitivity responses to vaccine components to local tissue reactions that are annoying but not significantly detrimental to the patient. The pathogenesis of these responses and the consequent clinical outcomes are discussed. Overstimulation of the immune response and the potential rela...
In vivo evaluation of effects of sedation on results of acoustoelastography of the superficial digital flexor tendons in clinically normal horses.
American journal of veterinary research    November 29, 2017   Volume 78, Issue 12 1421-1425 doi: 10.2460/ajvr.78.12.1421
De Gasperi D, Dzierzak SL, Muir P, Vanderby R, Brounts SH.OBJECTIVE To assess the effects of sedation on results of acoustoelastography of the superficial digital flexor tendons (SDFTs) in clinically normal horses. ANIMALS 27 clinically normal horses. PROCEDURES For each horse, the pathology index (PI) for the SDFT of each thoracic limb was determined by use of acoustoelastography at 4 locations (5, 10, 15, and 20 cm distal to the accessory carpal bone). Horses were evaluated before and after they were sedated with a combination of detomidine hydrochloride (0.01 mg/kg, IV) and butorphanol tartrate (0.01 mg/kg, IV). A repeated-measures ANOVA was used ...
Preliminary investigation of orally administered benazepril in horses with left-sided valvular regurgitation.
Equine veterinary journal    November 28, 2017   Volume 50, Issue 4 446-451 doi: 10.1111/evj.12773
Afonso T, Giguère S, Brown SA, Barton MH, Rapoport G, Barba M, Dembek KA, Toribio RE, Coleman AE.Despite the paucity of data available, orally administered angiotensin-converting enzyme (ACE) inhibitors are empirically used in horses with valvular regurgitation. Objective: Evaluate the echocardiographic and hormonal changes in response to oral benazepril in horses with left-sided valvular regurgitation. Methods: Prospective, randomised double-blind, placebo-controlled trial. Methods: Horses with mitral valve (MR) and/or aortic valve regurgitation (AR) received oral benazepril (n = 6) at a dosage of 1 mg/kg q 12 h or a placebo (n = 5) for 28 days. Echocardiography was performed before drug...
24-Hour Kinetics of Cardiac Troponin-T Using a “High-Sensitivity” Assay in Thoroughbred Chuckwagon Racing Geldings after Race and Associated Clinical Sampling Guidelines.
Journal of veterinary internal medicine    November 24, 2017   Volume 32, Issue 1 433-440 doi: 10.1111/jvim.14870
Shields E, Seiden-Long I, Massie S, Leguillette R.A "high-sensitivity" cardiac troponin-T (hscTnT) assay recently has been validated for use in horses and is a specific biomarker of myocardial damage. Postexercise release kinetics of cTnT utilizing the hscTnT assay have yet to be established in horses. Objective: To determine: (1) cTnT release kinetics in racing Thoroughbreds after a high-intensity 5/8th mile Chuckwagon race; (2) the effects of age on pre- and postrace cTnT concentrations; and (3) sampling guidelines for clinicians evaluating horses presenting after exercise. Methods: Samples were obtained from 38 Thoroughbred geldings aged 5...
Paradigm shifts in understanding equine laminitis.
Veterinary journal (London, England : 1997)    November 22, 2017   Volume 231 33-40 doi: 10.1016/j.tvjl.2017.11.011
Patterson-Kane JC, Karikoski NP, McGowan CM.Laminitis, one of the most debilitating conditions of all equids, is now known to be the result of several systemic disease entities. This finding, together with other recent developments in the field of laminitis research, have provoked a rethink of our clinical and research strategies for this condition. First, laminitis is now considered to be a clinical syndrome associated with systemic disease (endocrine disease, sepsis or systemic inflammatory response syndrome, SIRS) or altered weight bearing rather than being a discrete disease entity. Next, laminitis associated with endocrine disease ...
Neosaxitoxin, a Paralytic Shellfish Poison toxin, effectively manages bucked shins pain, as a local long-acting pain blocker in an equine model.
Toxicon : official journal of the International Society on Toxinology    November 13, 2017   Volume 141 15-17 doi: 10.1016/j.toxicon.2017.11.004
Riquelme G, Sepúlveda JM, Al Ghumgham Z, Del Campo M, Montero C, Lagos N.Local anesthesia is an effective method to control pain. Neosaxitoxin is a phycotoxin whose molecular mechanism includes a reversible inhibition of voltage-gated sodium channels at the axonal level, impeding nerve impulse propagation. The present study was designed to evaluate the clinical efficacy of Neosaxitoxin as a local long-acting pain blocker in horse bucked shins, and it was found to effectively control pain. While Neosaxitoxin and Gonyautoxin, another Paralytic Shellfish Poison (PSP) toxin, have been successfully used in humans as long-lasting pain blockers, this finding marks the fir...
Evaluation of the chemiluminescent enzyme immunoassay system for the measurement of testosterone in the serum and whole blood of stallions.
The Journal of reproduction and development    November 11, 2017   Volume 64, Issue 1 41-47 doi: 10.1262/jrd.2017-099
Toishi Y, Tsunoda N, Nagata SI, Kirisawa R, Nagaoka K, Watanabe G, Yanagawa Y, Katagiri S, Taya K.Testosterone (T) concentration is a useful indicator of reproductive function in male animals. However, T concentration is not usually measured in veterinary clinics, partly due to the unavailability of reliable and rapid assays for animal samples. In this study, a rapid chemiluminescent enzyme immunoassay system (CLEIA system) that was developed for the measurement of T concentration in humans use was validated for stallion blood samples. First, serum T concentrations were measured using the CLEIA system and compared with those measured by a fluoroimmunoassay that has been validated for use i...
Descriptive study of current therapeutic practices, clinical reproductive findings and incidence of pregnancy loss in intensively managed thoroughbred mares.
Animal reproduction science    November 10, 2017   Volume 188 74-84 doi: 10.1016/j.anireprosci.2017.11.011
Rose BV, Firth M, Morris B, Roach JM, Wathes DC, Verheyen KLP, de Mestre AM.Therapeutic practices in equine reproductive medicine have dramatically evolved over the last 20 years but current usage is not described. The aims of this study were to provide a description of medication use and clinical findings of reproductive examinations alongside measures of reproductive efficiency in thoroughbreds. A prospective cohort study was conducted in the 2013 and 2014 breeding seasons. Mare and stallion details, information on veterinary interventions and findings of reproductive ultrasound scans were collected using questionnaires and entered into a custom-designed Microsoft A...
Standing thyroidectomy in 10 horses.
Veterinary surgery : VS    November 8, 2017   Volume 47, Issue 1 86-92 doi: 10.1111/vsu.12744
Marcatili M, Voss SJ, Pollock PJ.To describe a surgical technique for thyroidectomy in horses with thyroid neoplasia under standing sedation and local anesthesia. Methods: Retrospective study. Methods: Client-owned horses (n = 10). Methods: Medical records of horses with a history of thyroid enlargement were included in the study if thyroid gland enlargement was treated surgically via hemi- or bilateral thyroidectomy, with the horse standing and sedated. Data derived from follow-up clinical examination, performance level, recurrence, and cosmetic outcome were evaluated. Results: Thyroid enlargement was unilateral in 8 and...
Periocular Neoplasia in the Horse.
The Veterinary clinics of North America. Equine practice    November 7, 2017   Volume 33, Issue 3 551-562 doi: 10.1016/j.cveq.2017.08.004
Estell K.Periocular neoplasia is common in horses. Treatment of the periocular skin and ocular adnexal structures can be technically challenging. Common neoplastic conditions, a treatment algorithm, surgical principles, and therapeutic modalities are reviewed. Regardless of the type of neoplasia found or the treatment that is applied, success is most likely when the neoplastic tumor is small.
Comparison of two blood sampling techniques for the determination of coagulation parameters in the horse: Jugular venipuncture and indwelling intravenous catheter.
Equine veterinary journal    November 2, 2017   Volume 50, Issue 3 333-338 doi: 10.1111/evj.12764
Mackenzie CJ, McGowan CM, Pinchbeck G, Carslake HB.Evaluation of coagulation status is an important component of critical care. Ongoing monitoring of coagulation status in hospitalised horses has previously been via serial venipuncture due to concerns that sampling directly from the intravenous catheter (IVC) may alter the accuracy of the results. Adverse effects such as patient anxiety and trauma to the sampled vessel could be avoided by the use of an indwelling IVC for repeat blood sampling. Objective: To compare coagulation parameters from blood obtained by jugular venipuncture with IVC sampling in critically ill horses. Methods: Prospectiv...
Equine pituitary pars intermedia dysfunction: An international survey of veterinarians’ approach to diagnosis, management, and estimated prevalence.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire    October 31, 2017   Volume 81, Issue 4 261-269 
Carmalt JL, Waldner CL, Allen AL.The objectives of the present study were to determine if diagnosis and treatment of equine pituitary pars intermedia dysfunction (PPID) vary by geographic region and to report the prevalence of PPID in horses as observed by veterinarians across locations. An online questionnaire was developed for veterinarians who treat horses. Veterinary associations, especially equine specialty subgroups, were contacted and a survey link was sent to members of each organization. Generalized linear models were used to examine whether the method of diagnosis and treatment of this condition, as well as its repo...
A Rare Case of Deep Digital Flexor Tendinopathy following Centesis of the Navicular Bursa.
Frontiers in veterinary science    October 16, 2017   Volume 4 169 doi: 10.3389/fvets.2017.00169
Froydenlund TJ, Meehan LJ, Morrison LR, Labens R.Navicular bursa (NB) centesis is a common diagnostic and therapeutic procedure in equine practice. This case report documents the clinical, diagnostic imaging and histological findings in a horse with a suspected iatrogenic deep digital flexor tendon (DDFT) injury following centesis of the NB a modified distal plantar approach (placement of two needles in a weight bearing position). Although it cannot be proven with absolute certainty, the authors believe that this is the first reported case where NB centesis is the likely cause of a DDFT lesion, and with magnetic resonance imaging performed ...
Encapsulation of Equine Endothelial Colony Forming Cells in Highly Uniform, Injectable Hydrogel Microspheres for Local Cell Delivery.
Tissue engineering. Part C, Methods    October 12, 2017   Volume 23, Issue 11 815-825 doi: 10.1089/ten.TEC.2017.0233
Seeto WJ, Tian Y, Winter RL, Caldwell FJ, Wooldridge AA, Lipke EA.A common challenge in cell therapy is the inability to routinely maintain survival and localization of injected therapeutic cells. Delivering cells by direct injection increases the flexibility of clinical applications, but may cause low cell viability and retention rates due to the high shear forces in the needle and mechanical wash out. In this study, we encapsulated endothelial colony forming cells (ECFCs) in poly(ethylene glycol)-fibrinogen (PF) hydrogel microspheres using a custom-built microfluidic device; this system supports rapid encapsulation of high cell concentrations (10 million c...
Management of combat-related facial injuries.
La Tunisie medicale    October 11, 2017   Volume 94, Issue 12 856 
Mardassi A, Turki S, Mbarek H, Hachicha A, Chebbi G, Benzarti S, Abouda M.Combat-related facial injuries involve various lesions of the mouth, the eye sockets and the facial bones. The goal of this study is to precise the particularities of these affections and their therapeutic management. Methods: A retrospective study was performed about 56 cases of combat-related facial injuries over a period of 5 years (2010 - 2014). Results: Our study included 56 male patients with an average age of 29 years (20-37). The trauma occurred during a real security intervention in all the cases. It was isolated in 18 cases and associated to other lesions in 38 cases. Clinical examin...
Open standing castration in Thoroughbred racehorses in Hong Kong: Prevalence and severity of complications 30 days post-castration.
Equine veterinary journal    October 7, 2017   Volume 50, Issue 3 327-332 doi: 10.1111/evj.12758
Rosanowski SM, MacEoin F, Graham RJTY, Riggs CM.Complications following open standing castration (OSC) in Thoroughbred racehorses are well recognised but variation in their prevalence and severity between populations is not well documented. Objective: To describe the prevalence and severity of complications in the 30 days following OSC. Methods: A retrospective cohort study of veterinary clinical records relating to horses that underwent OSC between July 2007 and July 2012. Methods: Complications were graded on a severity score from N, no complications, to C3, severe complications. Additional data were accessed for each horse including age,...
Advanced Imaging of the Equine Eye.
The Veterinary clinics of North America. Equine practice    October 3, 2017   Volume 33, Issue 3 607-626 doi: 10.1016/j.cveq.2017.07.006
Gilger BC.This article reviews the literature for studies describing advanced imaging of the equine eye as a reference for practitioners to help in the selection of image modalities, describe how to use the instruments, and help interpret the image findings. Indications for, technique of, and image interpretation of advanced image modalities such as ultrasound, computed tomography, MRI, optical coherence tomography, confocal microscopy, and angiography are reviewed. The article is organized anatomically, not by instrument, so that the reader will be able to quickly research ways to image specific diseas...
Retrospective evaluation of 155 adult equids and 21 foals with tetanus from Western, Northern, and Central Europe (2000-2014). Part 2: Prognostic assessment.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    September 28, 2017   Volume 27, Issue 6 697-706 doi: 10.1111/vec.12669
van Galen G, Rijckaert J, Mair T, Amory H, Armengou L, Bezdekova B, Durie I, Findshøj Delany R, Fouché N, Haley L, Hewetson M, van den Hoven R....To identify prognostic variables for adult equids and foals with tetanus. Methods: Multicenter retrospective study (2000-2014). Methods: Twenty Western, Northern, and Central European university teaching hospitals and private referral centers. Methods: One hundred fifty-five adult equids and 21 foals with tetanus. Methods: None. Results: Variables from history and clinical examination were statistically compared between survivors and nonsurvivors (adults: 49 survivors, 85 nonsurvivors; foals: 7 survivors, 10 nonsurvivors). Cases euthanized for financial reasons were excluded. Mortality rates i...
Antifungal Therapy in Equine Ocular Mycotic Infections.
The Veterinary clinics of North America. Equine practice    September 27, 2017   Volume 33, Issue 3 583-605 doi: 10.1016/j.cveq.2017.08.001
Ledbetter EC.Fungi are clinically important causes of ocular infections in the horse. Keratomycosis is the most common; however, a diverse range of mycotic infections, affecting numerous ocular tissues, may be encountered. Many equine mycoses are diagnostic and therapeutic challenges. Prompt and appropriate treatment is essential to minimize morbidity and reduce the likelihood of vision loss. Knowledge of the characteristics and properties of equine ophthalmology antifungal medications is essential to selecting an optimal treatment strategy, including selection of appropriate medication and effective admin...
Neuro-ophthalmology in the Horse.
The Veterinary clinics of North America. Equine practice    September 27, 2017   Volume 33, Issue 3 541-549 doi: 10.1016/j.cveq.2017.07.001
Myrna KE.This article provides a brief, clinically relevant review of neurologic disorders of the eye. A description of the neuro-ophthalmic examination is provided. Stepwise descriptions of the most common neuro-ophthalmic abnormalities are provided along with common rule outs.
Comparison of insertion characteristics of tapered and cylindrical transfixation pins in third metacarpal bones of equine cadavers.
American journal of veterinary research    September 26, 2017   Volume 78, Issue 10 1200-1209 doi: 10.2460/ajvr.78.10.1200
Adams MK, Lescun TB, Mechem AS, Johnson WR, Griffin TH, Main RP.OBJECTIVE To compare heat generation and mechanical bone damage for tapered and cylindrical transfixation pins during drilling, tapping, and pin insertion in equine third metacarpal bones. SAMPLE 16 pairs of cadaveric equine third metacarpal bones. PROCEDURES For cylindrical pin insertion, a 6.2-mm hole was drilled and tapped with a cylindrical tap, and then a standard 6.3-mm pin was inserted. For tapered pin insertion, a 6.0-mm hole was drilled, reamed with a tapered reamer, and tapped with a tapered tap, and then a 6.3-mm tapered pin was inserted. Paired t tests and 1-way ANOVAs were used to...
Equine corporate practice: is it inevitable and will it benefit vets and their clients?
The Veterinary record    September 25, 2017   Volume 181, Issue 12 312-313 doi: 10.1136/vr.j4359
No abstract available
Equine analgesia guidelines to be developed for first-opinion practices.
The Veterinary record    September 25, 2017   Volume 181, Issue 12 305 doi: 10.1136/vr.j4352
No abstract available
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