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Topic:Equine Diseases

Equine diseases encompass a wide range of health conditions that can affect horses, including infectious diseases, metabolic disorders, and genetic conditions. These diseases can impact the overall health, performance, and well-being of horses. Common equine diseases include equine influenza, equine herpesvirus, laminitis, and equine metabolic syndrome. Diagnosis and management of these diseases often require a combination of clinical evaluation, laboratory testing, and appropriate treatment strategies. This page gathers peer-reviewed research studies and scholarly articles that explore the etiology, pathophysiology, diagnosis, and treatment options for various equine diseases, providing valuable insights for veterinarians and researchers in the field.
Venom and Antivenom of the Redback Spider (Latrodectus hasseltii) in Japan. Part II. Experimental Production of Equine Antivenom against the Redback Spider.
Japanese journal of infectious diseases    October 31, 2017   Volume 70, Issue 6 635-641 doi: 10.7883/yoken.JJID.2017.125
Mori S, Horita A, Ginnaga A, Miyatsu Y, Sawabe K, Matsumura T, Ato M, Yamamoto A, Shibayama K, Arai S, Yamagishi T, Takahashi M, Taki H, Hifumi T.This is the first report on large-scale experimental production of an equine antivenom against the redback spider (Latrodectus hasseltii) lived in Japan. We captured 10,000 redback spiders in Japan and prepared the toxoids of crude venom extract, mixed the toxoids with a mineral oil adjuvant, and immunized healthy horses repeatedly over a period of several weeks. Thereafter, we separated the horse plasma, purified the γ-globulin fraction, and stocked it as a purified antivenom concentrate. Consequently, we manufactured approximately 6,500 vials of a single-dose freeze-dried test lot from a po...
Osteochondritis dissecans-like lesions of the occipital condyle and cervical articular process joints in a Saddlebred colt horse.
Acta veterinaria Scandinavica    October 30, 2017   Volume 59, Issue 1 76 doi: 10.1186/s13028-017-0345-5
Lim CK, Hawkins JF, Vanderpool AL, Heng HG, Gillespie Harmon CC, Lenz SD.Osteochondritis dissecans (OCD) is a sequela to osteochondrosis, whereby the cartilage superficial to the site of osteochondrosis fractures and gives rise to osteochondral fragments in the affected joint. In this case, both the radiological and computed tomography findings were supportive of classical severe OCD but the histologic findings were not supportive of the diagnosis of OCD. Methods: A 1 year and 6 months old, Saddlebred, colt was presented for evaluation of chronic cervical pain. Standing laterolateral radiographs revealed an osteochondral fragment with corresponding irregular subc...
Differential Diagnosis of Flavivirus Infections in Horses Using Viral Envelope Protein Domain III Antigens in Enzyme-Linked Immunosorbent Assay.
Vector borne and zoonotic diseases (Larchmont, N.Y.)    October 30, 2017   Volume 17, Issue 12 825-835 doi: 10.1089/vbz.2017.2172
Piyasena TBH, Setoh YX, Hobson-Peters J, Prow NA, Bielefeldt-Ohmann H, Khromykh AA, Perera D, Cardosa MJ, Kirkland PD, Hall RA.In Australia, infection of horses with the West Nile virus (WNV) or Murray Valley encephalitis virus (MVEV) occasionally results in severe neurological disease that cannot be clinically differentiated. Confirmatory serological tests to detect antibody specific for MVEV or WNV in horses are often hampered by cross-reactive antibodies induced to conserved epitopes on the envelope (E) protein. This study utilized bacterially expressed recombinant antigens derived from domain III of the E protein (rE-DIII) of MVEV and WNV, respectively, to determine whether these subunit antigens provided specific...
Novel gene therapy gives competition horses new lease of life after lameness.
The Veterinary record    October 28, 2017   Volume 181, Issue 17 437 doi: 10.1136/vr.j4994
No abstract available
Equine infectious anaemia in Europe: an ongoing threat to the UK.
The Veterinary record    October 28, 2017   Volume 181, Issue 17 442-446 doi: 10.1136/vr.j4721
Roberts H.Helen Roberts of Defra's International Disease Monitoring team sets out the situation regarding equine infectious anaemia in Europe, the threat to the UK and the expectations of disease control measures in light of an outbreak being detected.
Clinical characteristics and muscle glycogen concentrations in warmblood horses with polysaccharide storage myopathy.
American journal of veterinary research    October 28, 2017   Volume 78, Issue 11 1305-1312 doi: 10.2460/ajvr.78.11.1305
Lewis SS, Nicholson AM, Williams ZJ, Valberg SJ.OBJECTIVE To characterize clinical findings for polysaccharide storage myopathy (PSSM) in warmblood horses with type 1 PSSM (PSSM1; caused by mutation of the glycogen synthase 1 gene) and type 2 PSSM (PSSM2; unknown etiology). SAMPLE Database with 3,615 clinical muscle biopsy submissions. PROCEDURES Reported clinical signs and serum creatine kinase (CK) and aspartate aminotransferase (AST) activities were retrospectively analyzed for horses with PSSM1 (16 warmblood and 430 nonwarmblood), horses with PSSM2 (188 warmblood and 646 nonwarmblood), and warmblood horses without PSSM (278). Lameness e...
Reference values of two-dimensional and M-mode echocardiographic measurements as a function of body size in various equine breeds and in ponies.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    October 27, 2017   Volume 19, Issue 6 492-501 doi: 10.1016/j.jvc.2017.08.008
Al-Haidar A, Moula N, Leroux A, Farnir F, Deleuze S, Sandersen C, Amory H.The aim of this study was to establish echocardiographic reference values for the equine species using allometric regression equations based on body weight (BW) and thoracic circumference (TC). Methods: A total of 239 horses or ponies were studied, including 65 warmbloods, 33 Standardbreds, 41 Thoroughbreds, 32 Arabian horses, 28 draft horses, and 40 ponies aged from 1 day to 30 years, weighing from 18 to 890 kg, with no evidence of cardiac disease. Methods: For each horse or pony, a two-dimensional and M-mode echocardiography was performed. Within each breed, the relationships between BW or ...
A time-course evaluation of inflammatory and oxidative markers following high-intensity exercise in horses: a pilot study.
Journal of applied physiology (Bethesda, Md. : 1985)    October 26, 2017   Volume 124, Issue 4 860-865 doi: 10.1152/japplphysiol.00461.2017
MacNicol JL, Lindinger MI, Pearson W.Exercise is a physiological stress resulting in reactive oxygen species and inflammatory mediators, the accumulation of which are thought to contribute to degenerative articular diseases. The horse is of particular interest in this regard as equine athletes are frequently exposed to repetitive bouts of high-intensity exercise. The purpose of this study was to provide a detailed description of the response of articular and systemic oxidative and inflammatory biomarkers following high-intensity, exhaustive exercise in horses. A group of horses (Ex) underwent repeated bouts of high-intensity exer...
High Occurrence of Methicillin-Resistant Staphylococcus aureus in Horses at Slaughterhouses Compared with Those for Recreational Activities: A Professional and Food Safety Concern?
Foodborne pathogens and disease    October 25, 2017   Volume 14, Issue 12 735-741 doi: 10.1089/fpd.2017.2300
Parisi A, Caruso M, Normanno G, Latorre L, Miccolupo A, Fraccalvieri R, Intini F, Manginelli T, Santagada G.The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) in horses and its zoonotic potential is poorly understood. The objective of this study is to provide data on the prevalence and genetic characteristics of MRSA isolated from horses on farms, at racecourses, and at slaughterhouses in Italy, using standard and molecular methods. In addition, we report the prevalence of MRSA in horse handlers. Among 388 horses tested by nasal swabs, 27 (7%) were positive for MRSA ST398 (t011, t899, t1255) and ST1 (t127). The prevalence of MRSA in horses tested at slaughterhouses was significan...
The role of nonlinear coupling in Human-Horse Interaction: A preliminary study. Lanata A, Guidi A, Valenza G, Baragli P, Scilingo EP.This study focuses on the analysis of human-horse dynamic interaction using cardiovascular information exclusively. Specifically, the Information Theoretic Learning (ITL) approach has been applied to a Human-Horse Interaction paradigm, therefore accounting for the nonlinear information of the heart-heart interplay between humans and horses. Heartbeat dynamics was gathered from humans and horses during three experimental conditions: absence of interaction, visual-olfactory interaction, and brooming. Cross Information Potential, Cross Correntropy, and Correntropy Coefficient were computed to qua...
Allogeneic Stem Cells Alter Gene Expression and Improve Healing of Distal Limb Wounds in Horses.
Stem cells translational medicine    October 24, 2017   Volume 7, Issue 1 98-108 doi: 10.1002/sctm.17-0071
Textor JA, Clark KC, Walker NJ, Aristizobal FA, Kol A, LeJeune SS, Bledsoe A, Davidyan A, Gray SN, Bohannon-Worsley LK, Woolard KD, Borjesson DL.Distal extremity wounds are a significant clinical problem in horses and humans and may benefit from mesenchymal stem cell (MSC) therapy. This study evaluated the effects of direct wound treatment with allogeneic stem cells, in terms of gross, histologic, and transcriptional features of healing. Three full-thickness cutaneous wounds were created on each distal forelimb in six healthy horses, for a total of six wounds per horse. Umbilical cord-blood derived equine MSCs were applied to each wound 1 day after wound creation, in one of four forms: (a) normoxic- or (b) hypoxic-preconditioned cells ...
Occurrence, treatment protocols, and outcomes of colic in horses within Nairobi County, Kenya.
Veterinary world    October 22, 2017   Volume 10, Issue 10 1255-1263 doi: 10.14202/vetworld.2017.1255-1263
Gitari A, Nguhiu J, Varma V, Mogoa E.The aim of this study was to determine the treatments and their outcomes in horses with colic in Nairobi County, Kenya. Methods: This is a retrospective study to determine the occurrence, treatments, pain management, and outcomes of colic in horses in Nairobi County. Association between pain management protocols and the outcomes of colic with regard to recovery or death was also determined. Data collected from four equine practitioners were organized manually and given numerical codes as appropriate to facilitate entry into the computer. The coded data were entered into Microsoft Excel 2010 an...
Equine disease surveillance: quarterly summary.
The Veterinary record    October 21, 2017   Volume 181, Issue 16 419-422 doi: 10.1136/vr.j4715
of surveillance testing, April to June 2017International disease occurrence in the second quarter of 2017These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
Equine disease surveillance: quarterly summary.
The Veterinary record    October 21, 2017   Volume 181, Issue 16 419-422 doi: 10.1136/vr.j4715
of surveillance testing, April to June 2017International disease occurrence in the second quarter of 2017These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
Equine disease surveillance: quarterly summary.
The Veterinary record    October 21, 2017   Volume 181, Issue 16 419-422 doi: 10.1136/vr.j4715
of surveillance testing, April to June 2017International disease occurrence in the second quarter of 2017These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
Equine disease surveillance: quarterly summary.
The Veterinary record    October 21, 2017   Volume 181, Issue 16 419-422 doi: 10.1136/vr.j4715
of surveillance testing, April to June 2017International disease occurrence in the second quarter of 2017These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
First evidence for the presence of aquaporins in stallion sperm.
Reproduction in domestic animals = Zuchthygiene    October 21, 2017   Volume 52 Suppl 4 61-64 doi: 10.1111/rda.13059
Bonilla-Correal S, Noto F, Garcia-Bonavila E, Rodríguez-Gil JE, Yeste M, Miro J.Aquaporins (AQPs) are transmembrane proteins found in all cells and are responsible for the transport of water and small solutes. While these proteins have been found in the spermatozoa of humans, rodents, pigs and cattle, where not only do they play a role for the regulation of sperm volume but are also related with the sperm resilience to withstand freeze-thawing procedures, their presence in stallion sperm is yet to be reported. Therefore, the objectives of this work were as follows: (i) to determine whether AQP3, AQP7 and AQP11 are present in stallion sperm and (ii) to investigate whether ...
Equine disease surveillance: quarterly summary.
The Veterinary record    October 21, 2017   Volume 181, Issue 16 419-422 doi: 10.1136/vr.j4715
of surveillance testing, April to June 2017International disease occurrence in the second quarter of 2017These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
Strongyloides westeri worm and egg counts in naturally infected young horses.
Veterinary parasitology    October 20, 2017   Volume 248 1-3 doi: 10.1016/j.vetpar.2017.10.010
Miller FL, Bellaw JL, Lyons ET, Nielsen MK.Strongyloides westeri is a threadworm parasite found in the small intestine mainly in foals at up to about 4 months of age. This parasite is associated with small intestinal enteritis and diarrhea as well as skin irritation and a clinical syndrome called "frenzied behavior" due to percutaneous invasion. The aim of this study was to investigate S. westeri parasite burdens in age groups older than the initial lactogenic transmission phase. Secondary aims were to examine the impact of host age and gender on worm burden and egg output in naturally infected foals. Thirteen foals were enrolled in th...
An interview with Katrin Hinrichs.
Biology of reproduction    October 19, 2017   Volume 97, Issue 5 657-659 doi: 10.1093/biolre/iox126
Hansen PJ.No abstract available
Wetland characteristics linked to broad-scale patterns in Culiseta melanura abundance and eastern equine encephalitis virus infection.
Parasites & vectors    October 18, 2017   Volume 10, Issue 1 501 doi: 10.1186/s13071-017-2482-0
Skaff NK, Armstrong PM, Andreadis TG, Cheruvelil KS.Eastern equine encephalitis virus (EEEV) is an expanding mosquito-borne threat to humans and domestic animal populations in the northeastern United States. Outbreaks of EEEV are challenging to predict due to spatial and temporal uncertainty in the abundance and viral infection of Cs. melanura, the principal enzootic vector. EEEV activity may be closely linked to wetlands because they provide essential habitat for mosquito vectors and avian reservoir hosts. However, wetlands are not homogeneous and can vary by vegetation, connectivity, size, and inundation patterns. Wetlands may also have diffe...
Anthelmintic therapy of equine cyathostomin nematodes – larvicidal efficacy, egg reappearance period, and drug resistance.
International journal for parasitology    October 16, 2017   Volume 48, Issue 2 97-105 doi: 10.1016/j.ijpara.2017.08.009
Bellaw JL, Krebs K, Reinemeyer CR, Norris JK, Scare JA, Pagano S, Nielsen MK.Cyathostomins are ubiquitous in grazing horses across the world, and anthelmintic resistance has been reported with increasing levels over past decades. The aims of the present study were (i) to investigate the efficacy against encysted larval stages of moxidectin (0.4 mg/kg) and fenbendazole (10 mg/kg daily for five consecutive days) and compare these regimens at 2 and 5 weeks post-treatment, (ii) to investigate individual cyathostomin species associated with shortened egg reappearance periods, and (iii) to document species exhibiting decreased susceptibility to the evaluated compounds....
Racehorse injuries: Have we only got half the story?
Equine veterinary journal    October 14, 2017   Volume 49, Issue 6 697-699 doi: 10.1111/evj.12755
Stirk AJ.No abstract available
The importance of measuring skin resistance for electrical nociceptive stimulation in standing horses.
Equine veterinary journal    October 14, 2017   Volume 49, Issue 6 836 doi: 10.1111/evj.12700
Gozalo-Marcilla M, Luna SPL, Crosignani N, Puoli Filho JNP, Pelligand L, Taylor PM.No abstract available
Evaluation of Three Methods of Platelet-Rich Plasma for Treatment of Equine Distal Limb Skin Wounds.
Journal of equine veterinary science    October 14, 2017   Volume 72 1-7 doi: 10.1016/j.jevs.2017.10.009
Pereira RCDF, De La Côrte FD, Brass KE, da Silva Azevedo M, Gallio M, Cantarelli C, Dau SL, Cezar AS, Inkelmann MA.Wounds localized on the distal limbs in horses are difficulty healing. No studies have been conducted to evaluate homologous platelet-rich plasma (PRP) in horses. The aim of this study was to evaluate the effect upon applying autologous PRP, homologous PRP, and autologous PRP gel on the wound healing process of wounds on the distal limb of horses. To study a possible correlation between the platelet count and wound healing time, four skin wounds of 4 cm2 were surgically created on the dorsolateral aspect of the third metacarpus in eight healthy adult horses. Each skin wound was randomly treate...
Contributions to the knowledge of hard ticks (Acari: Ixodidae) in Colombia.
Ticks and tick-borne diseases    October 14, 2017   Volume 9, Issue 1 57-66 doi: 10.1016/j.ttbdis.2017.10.008
Rivera-Páez FA, Labruna MB, Martins TF, Perez JE, Castaño-Villa GJ, Ossa-López PA, Gil CA, Sampieri BR, Aricapa-Giraldo HJ, Camargo-Mathias MI.The known tick fauna of Colombia includes 58 species (15 Argasidae and 43 Ixodidae). To add to the knowledge of the biology of ticks in Colombia, hard ticks (Ixodidae) were collected from domestic animals or vegetation during 2014-2016 in 10 of Colombia's Departments. Ticks were identified to species through morphological examinations. Taxonomic identification was confirmed for some specimens by molecular methods, including phylogenetic analyses inferred from three tick genes (cytochrome c oxidase, 16S rDNA, second internal transcribed spacer). A total of 1745 tick specimens encompassing 8 spe...
Risk factors for race-day fatality, distal limb fracture and epistaxis in Thoroughbreds racing on all-weather surfaces in Great Britain (2000 to 2013).
Preventive veterinary medicine    October 13, 2017   Volume 148 58-65 doi: 10.1016/j.prevetmed.2017.10.003
Rosanowski SM, Chang YM, Stirk AJ, Verheyen KLP.The incidence of race-day injuries in Great Britain (GB) is higher on all-weather (AW) surfaces than on turf. However, to date no studies have focused on identifying risk factors for injury specific to AW racing. Therefore, the objective of the current study was to determine risk factors for fatality, distal limb fracture (DLF) and episodes of epistaxis in flat racing Thoroughbreds racing on AW surfaces in GB. Data included all flat racing starts on AW surfaces (n=258,193) and race-day veterinary events recorded between 2000 and 2013. Information on additional course-level variables was gather...
Serial-omics characterization of equine urine.
PloS one    October 13, 2017   Volume 12, Issue 10 e0186258 doi: 10.1371/journal.pone.0186258
Yuan M, Breitkopf SB, Asara JM.Horse urine is easily collected and contains molecules readily measurable using mass spectrometry that can be used as biomarkers representative of health, disease or drug tampering. This study aimed at analyzing microliter levels of horse urine to purify, identify and quantify proteins, polar metabolites and non-polar lipids. Urine from a healthy 12 year old quarter horse mare on a diet of grass hay and vitamin/mineral supplements with limited pasture access was collected for serial-omics characterization. The urine was treated with methyl tert-butyl ether (MTBE) and methanol to partition into...
Comparative Study of rhPDGF-BB Plus Equine-Derived Bone Matrix Versus rhPDGF-BB Plus β-TCP in the Treatment of Periodontal Defects.
The International journal of periodontics & restorative dentistry    October 13, 2017   Volume 37, Issue 6 825-832 doi: 10.11607/prd.3401
Lee JY, Na HJ, Kim HM, Lee SC, Lee JY, Chung CP, Seol YJ, Park YJ.The purpose of this study was to evaluate the efficacy and safety of equine-derived bone matrix as a carrier for recombinant human platelet-derived growth factor BB (rhPDGF-BB) versus beta-tricalcium phosphate (β-TCP) for the treatment of intraosseous periodontal defects in adult patients. This study was performed on 32 adults with advanced periodontal disease. Eligible subjects were randomized in 1:1 ratio into a test (rhPDGF-BB-coated equine-derived bone matrix) or control group (rhPDGF-BB-coated β-TCP). Probing pocket depth (PD), clinical attachment level (CAL), gingival recession (GR), a...
Evaluation of accuracy and precision of a smartphone based automated parasite egg counting system in comparison to the McMaster and Mini-FLOTAC methods.
Veterinary parasitology    October 12, 2017   Volume 247 85-92 doi: 10.1016/j.vetpar.2017.10.005
Scare JA, Slusarewicz P, Noel ML, Wielgus KM, Nielsen MK.Fecal egg counts are emphasized for guiding equine helminth parasite control regimens due to the rise of anthelmintic resistance. This, however, poses further challenges, since egg counting results are prone to issues such as operator dependency, method variability, equipment requirements, and time commitment. The use of image analysis software for performing fecal egg counts is promoted in recent studies to reduce the operator dependency associated with manual counts. In an attempt to remove operator dependency associated with current methods, we developed a diagnostic system that utilizes a ...