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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Characterization of equine CSN1S2 variants considering genetics, transcriptomics, and proteomics.
Journal of dairy science    December 17, 2015   Volume 99, Issue 2 1277-1285 doi: 10.3168/jds.2015-9807
Cieslak J, Pawlak P, Wodas L, Borowska A, Stachowiak A, Puppel K, Kuczynska B, Luczak M, Marczak L, Mackowski M.Currently, research interest is increasing in horse milk composition and its effect on human health. Despite previously published studies describing the presence of intra- and interbreed variability of equine milk components, no investigations have focused on the genetic background of this variation. Among horse caseins and the genes encoding them, least is known about the structure and expression of the α-S2 casein gene, CSN1S2. Herein, based on direct sequencing of the equine CSN1S2 coding sequence, we describe the presence of 51-bp insertion-deletion (in/del) polymorphism, which significan...
Methods for the cultivation of ciliated protozoa from the large intestine of horses.
FEMS microbiology letters    December 17, 2015   Volume 363, Issue 2 fnv233 doi: 10.1093/femsle/fnv233
Bełżecki G, Miltko R, Michałowski T, McEwan NR.This paper describes cultivation methods for ciliates from the digestive tract of horses. Members of three different genera were successfully grown in vitro for short periods of time. However, only cells belonging to the genus Blepharocorys, which resides in the horse's large intestine, were maintained for longer periods. This Blepharocorys culture was successfully grown in vitro after inoculation of freshly excreted horse faeces in culture medium containing a population of bacteria. The ciliates survived for over six months, and the density of their population varied between 1.7 × 10(3) and ...
Diagnosis and effects of urine contamination in cooled-extended stallion semen.
Theriogenology    December 17, 2015   Volume 85, Issue 7 1219-1224 doi: 10.1016/j.theriogenology.2015.12.002
Ellerbrock R, Canisso I, Feijo L, Lima F, Shipley C, Kline K.Urospermia is known to affect semen quality in many mammals, including stallions. Determinations of semen pH and creatinine and urea concentrations have been used to diagnose urine contamination in raw stallion semen. Unfortunately, practitioners suspecting urine contamination in cooled-shipped samples have no proven means to confirm the presence of urine. Therefore, the objectives of this study were (1) to assess the effects of urine contamination on sperm motility of extended fresh and cooled-stored stallion semen, (2) to evaluate the usefulness of semen color, odor, pH, and creatinine and u...
Comparison of Chemical and Surgical Vasectomy on Testicular Activity in Free-Roaming Horses (Equus caballus)
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians    December 17, 2015   Volume 46, Issue 4 815-824 doi: 10.1638/2014-0227.1
Scully CM, Lee RL, Pielstick L, Medlock J, Patton KM, Collins GH, Kutzler MA.Free-roaming horse (Equus caballus) management is a complex issue incorporating social, economic, emotional, political, and environmental factors. Currently, few proven field techniques exist for managing free-roaming horse population growth, which can reach 20-25% annually. Although there are several strategies available for sterilizing mares when managing free-roaming horse populations, surgical vasectomy is the only method used in the field for stallions. Some managers believe that surgically vasectomizing dominant stallions would have significant effects on reducing horse populations. Howe...
Streptococcus equi Detection Polymerase Chain Reaction Assay for Equine Nasopharyngeal and Guttural Pouch Wash Samples.
Journal of veterinary internal medicine    December 17, 2015   Volume 30, Issue 1 276-281 doi: 10.1111/jvim.13808
Boyle AG, Rankin SC, D○ L, Boston RC, Wheeler-Aceto H.Bacterial culture and polymerase chain reaction (PCR) assays for the detection of Streptococcus equi in nasopharyngeal washes (NPW) and guttural pouch lavage (GPL) samples have low sensitivity. In human diagnostics, processing of samples with flocked swabs has improved recovery rates of bacterial agents because of improved surface area and elution factors. Objective: For S. equi subsp. equi (S. equi) detection in NPW and GPL samples we hypothesized that: direct-PCR would be more reliable than flocked swab culture (FS culture); flocked swab PCR (FS-PCR) would be equivalent to direct-PCR; and FS...
Towards the elimination of excessive cobalt supplementation in racing horses: A pharmacological review.
Research in veterinary science    December 17, 2015   Volume 104 106-112 doi: 10.1016/j.rvsc.2015.12.007
Kinobe RT.Cobalt is an essential trace element for many vital physiological functions. Cobalt is also known to stabilise hypoxia-inducible transcription factors leading to increased expression of erythropoietin which activates production of red blood cells. This implies that cobalt can be used to enhance aerobic performance in racing horses. If this becomes a pervasive practice, the welfare of racing animals would be at risk because cobalt is associated with cardiovascular, haematological, thyroid gland and reproductive toxicity as observed in laboratory animals and humans. It is expected that similar e...
Use of whips in horse racing.
Australian veterinary journal    December 17, 2015   Volume 93, Issue 10 N23-N24 
Ben-David O.No abstract available
On the mineral core of ferritin-like proteins: structural and magnetic characterization.
Nanoscale    December 17, 2015   Volume 8, Issue 2 1088-1099 doi: 10.1039/c5nr04446d
García-Prieto A, Alonso J, Muñoz D, Marcano L, Abad Díaz de Cerio A, Fernández de Luis R, Orue I, Mathon O, Muela A, Fdez-Gubieda ML.It is generally accepted that the mineral core synthesized by ferritin-like proteins consists of a ferric oxy-hydroxide mineral similar to ferrihydrite in the case of horse spleen ferritin (HoSF) and an oxy-hydroxide-phosphate phase in plant and prokaryotic ferritins. The structure reflects a dynamic process of deposition and dissolution, influenced by different biological, chemical and physical variables. In this work we shed light on this matter by combining a structural (High Resolution Transmission Electron Microscopy (HRTEM) and Fe K-edge X-ray Absorption Spectroscopy (XAS)) and a magneti...
Multiple specificities of immunoglobulin M in equine fetuses infected with Leptospira interrogans indicate a competent immune response.
Equine veterinary journal    December 16, 2015   Volume 48, Issue 6 704-709 doi: 10.1111/evj.12527
Velineni S, Timoney JF, Artiushin SC, Donahue JM, Steinman M.Foals of mares infected with Leptospira interrogans serovar Pomona type kennewicki (Lk) may be aborted/stillborn or delivered as healthy foals. Is fetal survival explained in part by the immune response of the fetus to Leptospira antigens? Objective: To describe an outbreak of Leptospira abortion in which infected mares delivered dead/sick or normal foals and determine specificities of antibody in a collection of 54 fetuses from similar outbreaks. Methods: Outbreak investigation in combination with a case-control study of a larger set of samples from aborted fetuses. Methods: Serology and poly...
Prevalence of oro-dental pathology in a working horse population in Egypt and its relation to equine health.
Equine veterinary journal    December 16, 2015   Volume 49, Issue 1 26-33 doi: 10.1111/evj.12533
Salem SE, Townsend NB, Refaai W, Gomaa M, Archer DC.Oro-dental disease can have a significant impact on equine welfare. Objective: To determine the prevalence of oro-dental disease and to identify risk factors for oro-dental disorders and poor body condition scores (BCS) in a working horse population in Egypt. Methods: Cross-sectional survey. Methods: Oro-dental examination was performed on 450 working horses in 2 Egyptian provinces. Horse and management historical data were collected and horses were assigned to no/mild, moderate and severe dental disease categories based on findings on examination. Multivariable logistic regression and general...
Peer review: What’s expected and who benefits?
Equine veterinary journal    December 15, 2015   Volume 48, Issue 1 5 doi: 10.1111/evj.12538
Marr CM, Southwood L, Barnett T.No abstract available
Response to letter to the Editor. Epiduroscopy of the lumbosacral vertebral canal in the horse: Technique and endoscopic anatomy.
Equine veterinary journal    December 15, 2015   Volume 48, Issue 1 131 doi: 10.1111/evj.12494
Prange T, Shrauner BD, Blikslager AT.No abstract available
Sialolithiasis in horses: A retrospective study of 25 cases (2002-2013).
The Canadian veterinary journal = La revue veterinaire canadienne    December 15, 2015   Volume 56, Issue 12 1239-1244 
Carlson N, Eastman T, Winfield L.This study evaluated outcomes of surgical treatment of equine sialolithiasis, highlighting cases involving the proximal parotid salivary duct. Sialoliths in the proximal parotid duct were difficult to identify radiographically and more frequently associated with draining tracts and sialadenitis compared with sialoliths in the distal parotid duct. Ultrasonography confirmed the diagnosis of sialolithiasis in all cases in which there was no radiographic evidence of a sialolith. All cases of proximal parotid duct sialolithiasis required transcutaneous removal. A longer duration of illness was obse...
Targeted Metabolomics Approach To Detect the Misuse of Steroidal Aromatase Inhibitors in Equine Sports by Biomarker Profiling.
Analytical chemistry    December 15, 2015   Volume 88, Issue 1 764-772 doi: 10.1021/acs.analchem.5b03165
Chan GH, Ho EN, Leung DK, Wong KS, Wan TS.The use of anabolic androgenic steroids (AAS) is prohibited in both human and equine sports. The conventional approach in doping control testing for AAS (as well as other prohibited substances) is accomplished by the direct detection of target AAS or their characteristic metabolites in biological samples using hyphenated techniques such as gas chromatography or liquid chromatography coupled with mass spectrometry. Such an approach, however, falls short when dealing with unknown designer steroids where reference materials and their pharmacokinetics are not available. In addition, AASs with fast...
Science in brief: Highlights from the applied physiology, muscle and genetics abstracts at the International Conference on Equine Exercise Physiology.
Equine veterinary journal    December 15, 2015   Volume 48, Issue 1 9-12 doi: 10.1111/evj.12484
Verdegaal EJ, Franklin SH.No abstract available
Science in brief: Report on the Havemeyer Foundation workshop on subchondral bone problems in the equine athlete.
Equine veterinary journal    December 15, 2015   Volume 48, Issue 1 6-8 doi: 10.1111/evj.12518
Smith MR, Kawcak CE, McIlwraith CW.No abstract available
In vitro maturation affects chromosome segregation, spindle morphology and acetylation of lysine 16 on histone H4 in horse oocytes.
Reproduction, fertility, and development    December 15, 2015   Volume 29, Issue 4 721-730 doi: 10.1071/RD15350
Franciosi F, Goudet G, Tessaro I, Papillier P, Dalbies-Tran R, Reigner F, Deleuze S, Douet C, Miclea I, Lodde V, Luciano AM.Implantation failure and genetic developmental disabilities in mammals are caused by errors in chromosome segregation originating mainly in the oocyte during meiosis I. Some conditions, like maternal ageing or in vitro maturation (IVM), increase the incidence of oocyte aneuploidy. Here oocytes from adult mares were used to investigate oocyte maturation in a monovulatory species. Experiments were conducted to compare: (1) the incidence of aneuploidy, (2) the morphology of the spindle, (3) the acetylation of lysine 16 on histone H4 (H4K16) and (4) the relative amount of histone acetyltransferase...
Efficacy of a single-formula acupuncture treatment for horses with palmar heel pain.
The Canadian veterinary journal = La revue veterinaire canadienne    December 15, 2015   Volume 56, Issue 12 1257-1260 
Robinson KA, Manning ST.Acupuncture is used without strong scientific evidence to treat many diseases of the horse, including palmar heel pain. Research is needed to provide evidence for the application of these treatments. Within the confines of our study, acupuncture did not reliably modulate palmar heel pain in horses. Efficacité d’un traitement d’acupuncture à formule simple pour les chevaux souffrant de douleur du talon palmaire. L’acupuncture est utilisée, en l’absence de solides preuves scientifiques, pour traiter plusieurs affections des chevaux, y compris la douleur du talon palmaire. De la recher...
Immunoglobulin E and allergy.
Equine veterinary journal    December 15, 2015   Volume 48, Issue 1 13-14 doi: 10.1111/evj.12513
Wagner B.No abstract available
Letter to the Editor. Epiduroscopy of the lumbosacral vertebral canal in the horse: Technique and endoscopic anatomy.
Equine veterinary journal    December 15, 2015   Volume 48, Issue 1 130 doi: 10.1111/evj.12489
Josephson E.No abstract available
Historical cases of anthrax in Sweden 1916-1961.
Transboundary and emerging diseases    December 15, 2015   Volume 64, Issue 3 892-898 doi: 10.1111/tbed.12456
Elvander M, Persson B, Sternberg Lewerin S.As in most European countries, anthrax was common in Swedish livestock during the centuries leading up to the mid-twentieth century. After 1957, the disease was regarded as practically extinct. However, in the past 7 years, three outbreaks have caused public alarm because of the risk of environmental contamination. Properly buried carcasses should present little risk of spore contamination, and instructions were in place to ensure this since the 1890s. However, as has been demonstrated in recent outbreaks, carcasses were not always adequately buried and viable spores may remain in some sites....
Effects of Intrauterine Devices in Mares: A Histomorphological and Immunohistochemical Evaluation of the Endometrium.
Reproduction in domestic animals = Zuchthygiene    December 14, 2015   Volume 51, Issue 1 98-104 doi: 10.1111/rda.12651
Klein V, Müller K, Schoon HA, Reilas T, Rivera del Alamo MM, Katila T.Oestrous suppression by intrauterine devices (IUDs) is caused by prolongation of luteal function, but the biological mechanism is unknown. The aim of the study was to investigate mechanisms which could explain the action of IUDs. Thirty mares were age-matched and either inseminated (AI, n = 15) or fitted with an IUD (IUD, n = 15) and subsequently divided into four groups: AI-P, pregnant (n = 8); AI-N, non-pregnant (n = 7); IUD-P, prolonged luteal phase (n = 7); and IUD-N, normal luteal phase (n = 8). The median ages were 5.5 and 7 years in AI-P and IUD-P groups and 14 and 11 years in AI-N and ...
Infundibula of equine maxillary cheek teeth: Part 2: Morphological variations and pathological changes.
Veterinary journal (London, England : 1997)    December 14, 2015   Volume 209 66-73 doi: 10.1016/j.tvjl.2015.11.023
Suske A, Pöschke A, Müller P, Wöber S, Staszyk C.Incomplete cemental filling of the infundibula of equine maxillary cheek teeth (CT) is a common feature. Depending on the extent of the defect, three stages of infundibular decay have been suggested. However, histomorphological criteria to identify non-pathological abnormalities and destructive changes have not been defined. Six hundred and eighty eight CT with no evidence of dental diseases and 55 diseased permanent, fully erupted maxillary CT were evaluated on a macroscopic level by assessing the occlusal surface and horizontal sections, including porphyrin assays to detect residual blood wi...
First isolation of Actinobacillus genomospecies 2 in Japan.
The Journal of veterinary medical science    December 12, 2015   Volume 78, Issue 4 701-703 doi: 10.1292/jvms.15-0597
Murakami M, Shimonishi Y, Hobo S, Niwa H, Ito H.We describe here the first isolation of Actinobacillus genomospecies 2 in Japan. The isolate was found in a septicemic foal and characterized by phenotypic and genetic analyses, with the latter consisting of 16S rDNA nucleotide sequence analysis plus multilocus sequence analysis using three housekeeping genes, recN, rpoA and thdF, that have been proposed for use as a genomic tool in place of DNA-DNA hybridization.
Cryptosporidium parvum and Enterocytozoon bieneusi in American Mustangs and Chincoteague ponies.
Experimental parasitology    December 12, 2015   Volume 162 24-27 doi: 10.1016/j.exppara.2015.12.004
Wagnerová P, Sak B, McEvoy J, Rost M, Sherwood D, Holcomb K, Kváč M.The prevalence of Cryptosporidium and microsporidia in feral horses, which have minimal contact with livestock and humans, is not currently known. We report the findings of a study on Cryptosporidium and microsporidia in 34 Mustangs and 50 Chincoteague ponies in the USA. Fecal samples were screened for presence of Cryptosporidium spp. by analysis of the small-subunit rRNA (SSU) and 60-kDa glycoprotein (gp60) genes, and Enterocytozoon bieneusi and Encephalitozoon spp. by analysis of the ribosomal internal transcribed spacer region (ITS). Cryptosporidium spp. and E. bieneusi were detected in 28/...
Substitution of egg yolk by a cyclodextrin-cholesterol complex allows a reduction of the glycerol concentration into the freezing medium of equine sperm.
Cryobiology    December 11, 2015   Volume 72, Issue 1 27-32 doi: 10.1016/j.cryobiol.2015.11.008
Blommaert D, Franck T, Donnay I, Lejeune JP, Detilleux J, Serteyn D.The aim of this work was to completely replace the egg yolk a classical diluent for freezing equine semen by a cyclodextrin-cholesterol complex. At the same time, the reduction in the glycerol content used for cryopreservation and the incubation time between sperm and the freezing media were evaluated. Horse ejaculates were frozen with four different freezing extenders: a frozen reference medium (IF) containing egg yolk and 2.5% glycerol and media without egg yolk but supplemented with 1.5 mg 2-hydroxypropyl-beta-cyclodextrin cholesterol (HPβCD-C) complex and containing either 1% (G1), 2% (G...
Efficacy and effects of various anti-crib devices on behaviour and physiology of crib-biting horses.
Equine veterinary journal    December 11, 2015   Volume 48, Issue 6 727-731 doi: 10.1111/evj.12534
Albright JD, Witte TH, Rohrbach BW, Reed A, Houpt KA.Crib-biting is a common oral stereotypy. Although most treatments involve prevention, the efficacy of various anti-crib devices, including surgically implanted gingival rings, has thus far not been empirically tested. Objective: Demonstrate the effect that 2 anti-crib collars, muzzle and gingival rings have on crib-biting, other maintenance behaviours, and cortisol levels in established crib-biting horses. Methods: Randomised, crossover clinical trial. Methods: In Experiment I, 2 anti-crib collars and a muzzle were used on 8 established crib-biting horses; horses wore each of 3 devices for 7 d...
Nodal Promotes Functional Luteolysis via Down-Regulation of Progesterone and Prostaglandins E2 and Promotion of PGF2α Synthetic Pathways in Mare Corpus Luteum.
Endocrinology    December 11, 2015   Volume 157, Issue 2 858-871 doi: 10.1210/en.2015-1362
Galvão A, Skarzynski D, Ferreira-Dias G.In the present work, we investigated the role of Nodal, an embryonic morphogen from the TGFβ superfamily in corpus luteum (CL) secretory activity using cells isolated from equine CL as a model. Expression pattern of Nodal and its receptors activin receptor A type IIB (ACVR2B), activin receptor-like kinase (Alk)-7, and Alk4, as well as the Nodal physiological role, demonstrate the involvement of this pathway in functional luteolysis. Nodal and its receptors were immune localized in small and large luteal cells and endothelial cells, except ACVR2B, which was not detected in the endothelium. Nod...
Clostridium difficile ribotypes in humans and animals in Brazil.
Memorias do Instituto Oswaldo Cruz    December 11, 2015   Volume 110, Issue 8 1062-1065 doi: 10.1590/0074-02760150294
Silva RO, Rupnik M, Diniz AN, Vilela EG, Lobato FC.Clostridium difficile is an emerging enteropathogen responsible for pseudomembranous colitis in humans and diarrhoea in several domestic and wild animal species. Despite its known importance, there are few studies about C. difficile polymerase chain reaction (PCR) ribotypes in Brazil and the actual knowledge is restricted to studies on human isolates. The aim of the study was therefore to compare C. difficile ribotypes isolated from humans and animals in Brazil. Seventy-six C. difficile strains isolated from humans (n = 25), dogs (n = 23), piglets (n = 12), foals (n = 7), calves (n = 7), one c...
Analysis of breed effects on semen traits in light horse, warmblood, and draught horse breeds.
Theriogenology    December 10, 2015   Volume 85, Issue 8 1375-1381 doi: 10.1016/j.theriogenology.2015.11.030
Gottschalk M, Sieme H, Martinsson G, Distl O.In the present study, systematic effects on semen quality traits were investigated in 381 stallions representing 22 breeds. All stallions were used for AI either at the Lower Saxon National Stud Celle or the North Rhine-Westphalian National Stud Warendorf. A total of 71,078 fresh semen reports of the years 2001 to 2014 were edited for analysis of gel-free volume, sperm concentration, total number of sperm, progressive motility, and total number of progressively motile sperm. Breed differences were studied for warmblood and light horse breeds of both national studs (model I) and for warmblood b...