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Topic:Equine Medicine

Equine Medicine encompasses the study and application of medical practices specifically related to the health and well-being of horses. This field involves the diagnosis, treatment, and prevention of diseases and disorders affecting equine species. It covers a wide range of topics, including internal medicine, surgery, reproduction, and pharmacology. Research in equine medicine often focuses on understanding the physiological and pathological processes unique to horses, as well as developing effective therapeutic interventions. This page aggregates peer-reviewed research studies and scholarly articles that explore various aspects of equine medicine, providing insights into the latest advancements and methodologies in the care and management of horse health.
Diagnostic ophthalmology.
The Canadian veterinary journal = La revue veterinaire canadienne    January 2, 2014   Volume 55, Issue 1 1263-1264 
Sandmeyer LS, Bauer BS, Grahn BH.No abstract available
AAEP/EVJ supplement 2013.
Equine veterinary journal. Supplement    December 1, 2013   Issue 45 1 doi: 10.1111/evj.12183
Ball BA, Pease A, Sellon DC, White NA.No abstract available
Distribution and predictive factors of seizure types in 104 cases.
Equine veterinary journal    October 30, 2013   Volume 46, Issue 4 441-445 doi: 10.1111/evj.12149
Lacombe VA, Mayes M, Mosseri S, Reed SM, Ou TH.Although many studies have been performed to classify seizures by type in man and small animals, a similar study in horses is lacking. Objective: The aims of this study were as follows: 1) to characterise the distribution of seizure types in 104 horses presented for seizure disorders to a referral veterinary hospital; and 2) to characterise the various types of seizures by identifying associated clinical factors. Methods: Retrospective analysis of clinical records. Methods: Seizures were classified based on seizure type, according to the most recent accepted definitions in both human and small...
Diagnostic ophthalmology.
The Canadian veterinary journal = La revue veterinaire canadienne    October 25, 2013   Volume 54, Issue 5 514-515 
Sandmeyer LS, Bauer BS, Grahn BH.No abstract available
Detection and elimination profile of cathinone in equine after norephedrine (Propalin®) administration using a validated liquid chromatography-tandem mass spectrometry method.
Analytical and bioanalytical chemistry    August 17, 2013   Volume 405, Issue 30 9711-9722 doi: 10.1007/s00216-013-7073-0
Yi R, Zhao S, Lam G, Sandhu J, Loganathan D, Morrissey B.Cathinone is the principal psychostimulant present in the leaves of khat shrub, which are widely used in East Africa and the Arab peninsula as an amphetamine-like stimulant. Cathinone readily undergoes metabolism in vivo to form less potent cathine and norephedrine as the metabolites. However, the presence of cathine and norephedrine in biological fluids cannot be used as an indicator of cathinone administration. The metabolism of pseudoephedrine and ephedrine, commonly used in cold and allergy medications, also produces cathine and norephedrine, respectively, as the metabolites. Besides, cath...
Conditioned medium from horse amniotic membrane-derived multipotent progenitor cells: immunomodulatory activity in vitro and first clinical application in tendon and ligament injuries in vivo.
Stem cells and development    July 30, 2013   Volume 22, Issue 22 3015-3024 doi: 10.1089/scd.2013.0214
Lange-Consiglio A, Rossi D, Tassan S, Perego R, Cremonesi F, Parolini O.We have recently demonstrated that heterologous transplantation of horse amniotic membrane-derived mesenchymal cells (AMCs) can be useful for cell therapy applications in tendon diseases, and hypothesized that these cells may promote tendon repair via paracrine-acting molecules targeting inflammatory processes. To test this hypothesis, here we examined the immunomodulatory characteristics of AMCs and of their conditioned medium (AMC-CM) in vitro, and studied the potential therapeutic effect of AMC-CM in thirteen different spontaneous horse tendon and ligament injuries in vivo. Our results demo...
Distal border fragments of the equine navicular bone: association between magnetic resonance imaging characteristics and clinical lameness. Yorke EH, Judy CE, Saveraid TC, McGowan CP, Caldwell FJ.Distal border fragments of the navicular bone are increasingly being detected due to the improved capabilities of magnetic resonance imaging (MRI), but their clinical significance remains unclear. The purpose of this retrospective study was to describe the location, size, and frequency of fragments in a cohort of horses presented for MRI of the foot and to compare MRI findings with severity of lameness. Archived MRI studies and medical records were searched from March 2006 to June 2008. Horses were included if a distal border fragment of the navicular bone was visible in MRI scans. Confidence ...
Early embryonic development, assisted reproductive technologies, and pluripotent stem cell biology in domestic mammals.
Veterinary journal (London, England : 1997)    June 27, 2013   Volume 197, Issue 2 128-142 doi: 10.1016/j.tvjl.2013.05.026
Hall V, Hinrichs K, Lazzari G, Betts DH, Hyttel P.Over many decades assisted reproductive technologies, including artificial insemination, embryo transfer, in vitro production (IVP) of embryos, cloning by somatic cell nuclear transfer (SCNT), and stem cell culture, have been developed with the aim of refining breeding strategies for improved production and health in animal husbandry. More recently, biomedical applications of these technologies, in particular, SCNT and stem cell culture, have been pursued in domestic mammals in order to create models for human disease and therapy. The following review focuses on presenting important aspects of...
Oral examination and charting: setting the basis for evidence-based medicine in the oral examination of equids.
The Veterinary clinics of North America. Equine practice    June 27, 2013   Volume 29, Issue 2 325-vi doi: 10.1016/j.cveq.2013.04.008
Menzies R.The oral examination is performed in equids to assess and monitor oral health status, provide diagnoses, and determine efficacy of treatments. While there is currently insufficient scientific material of adequate quality to enable evidence-based medicine in equine dentistry, this by no means negates the clinician's responsibility to provide oral health care in a scientific and ethical manner. To do so requires that the clinician be knowledgable and skilled in dentistry and general medicine, that each case upholds the principles of scientific method, and that data is gathered and appraised in a...
Myxochondroid metaplasia of the plantar foot: a distinctive pseudoneoplastic lesion resembling nuchal fibrocartilaginous pseudotumor and the equine digital cushion.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc    June 14, 2013   Volume 26, Issue 12 1561-1567 doi: 10.1038/modpathol.2013.116
Shon W, Folpe AL.Cartilaginous tumors of soft tissue are uncommon, with benign chondromas of soft parts greatly outnumbering rare soft-tissue chondrosarcomas. Over the past several years, we have seen in consultation a distinctive, benign-appearing chondroid soft-tissue lesion of the plantar foot that differs in a number of respects from chondroma of soft parts. Herein we report our experience with this distinctive lesion. A retrospective review of all cases from the foot in our soft-tissue consultation and institutional surgical pathology archives identified 9 similar cases, most often previously coded as 'fi...
Management of zebras and zebra hybrids (zebroids).
Compendium (Yardley, PA)    May 28, 2013   Volume 34, Issue 9 E4 
Wiedner EB, Lindsay WA, Isaza R.Equine practitioners are sometimes asked to treat zebras or zebra-horse or zebra-donkey hybrids. Although these equids are subject to many of the same health issues as domestic horses, they cannot be handled like horses and generally require heavy sedation to full anesthesia, even for minor procedures. This usually necessitates the use of ultrapotent narcotics administered by remote delivery systems. This article discusses the handling, sedation, anesthesia, and common medical issues of zebras and zebra hybrids.
Microdialysis in equine research: a review of clinical and experimental findings.
Veterinary journal (London, England : 1997)    May 6, 2013   Volume 197, Issue 3 553-559 doi: 10.1016/j.tvjl.2013.03.033
Sørensen MA, Jacobsen S, Petersen LJ.Microdialysis is a method for sampling compounds from extracellular fluid with minimal tissue trauma. Small hollow probes that are 0.2-0.5mm in diameter are inserted into the tissue and slowly perfused. The probe membrane is semi-permeable and a flux of the solutes occurs exclusively according to the concentration gradients. The recovered dialysate reflects changes in the composition of the extracellular water phase with a minor time delay. Because microdialysis is a continuous sampling method, it differs from point sample methods, such as blood sampling. The ability to obtain local measuremen...
The effect of 1% tropicamide-induced mydriasis and cycloplegia on spherical refraction of the adult horse.
Veterinary ophthalmology    May 6, 2013   Volume 17, Issue 2 120-125 doi: 10.1111/vop.12055
McMullen RJ, Davidson MG, Gilger BC.To determine the effects of tropicamide 1% on the refractive state of the adult equine globe and identify the most appropriate time period (in relation to mydriasis) to perform streak retinoscopy. Methods: Eight university-owned mares of various ages and breeds. Methods: Topical tropicamide 1% was applied to one randomly selected eye from each of the horses to induce mydriasis and cycloplegia. The contralateral eyes served as controls. Streak retinoscopy and pupillometry were performed prior to, and every 5 min after tropicamide 1% installation for 90 min. Results: All values are expressed as ...
Characterization and osteogenic potential of equine muscle tissue- and periosteal tissue-derived mesenchymal stem cells in comparison with bone marrow- and adipose tissue-derived mesenchymal stem cells.
American journal of veterinary research    May 1, 2013   Volume 74, Issue 5 790-800 doi: 10.2460/ajvr.74.5.790
Radtke CL, Nino-Fong R, Esparza Gonzalez BP, Stryhn H, McD○ LA.To characterize equine muscle tissue- and periosteal tissue-derived cells as mesenchymal stem cells (MSCs) and assess their proliferation capacity and osteogenic potential in comparison with bone marrow- and adipose tissue-derived MSCs. Methods: Tissues from 10 equine cadavers. Methods: Cells were isolated from left semitendinosus muscle tissue, periosteal tissue from the distomedial aspect of the right tibia, bone marrow aspirates from the fourth and fifth sternebrae, and adipose tissue from the left subcutaneous region. Mesenchymal stem cells were characterized on the basis of morphology, ad...
Clinical and molecular epidemiology of veterinary blastomycosis in Wisconsin.
BMC veterinary research    April 22, 2013   Volume 9 84 doi: 10.1186/1746-6148-9-84
Anderson JL, Sloss BL, Meece JK.Several studies have shown that Blastomyces dermatitidis, the etiologic agent of blastomycosis, is a genetically diverse pathogen. Blastomycosis is a significant health issue in humans and other mammals. Veterinary and human isolates matched with epidemiological case data from the same geographic area and time period were used to determine: (i) if differences in genetic diversity and structure exist between clinical veterinary and human isolates of B. dermatitidis and (ii) if comparable epidemiologic features differ among veterinary and human blastomycosis cases. Results: Genetic typing of 301...
Seek and ye shall find: cardiac arrhythmias in the horse.
Equine veterinary journal    April 10, 2013   Volume 45, Issue 3 270-272 doi: 10.1111/evj.12054
Physick-Sheard PW.No abstract available
Comment on Suthers and colleagues.
Equine veterinary journal    April 10, 2013   Volume 45, Issue 3 388 doi: 10.1111/evj.12072
Durham A.No abstract available
Getting a feel for equine colic.
The Veterinary record    April 9, 2013   Volume 172, Issue 14 354 doi: 10.1136/vr.f2119
No abstract available
What lies ahead in veterinary medicine.
Journal of the American Veterinary Medical Association    March 13, 2013   Volume 242, Issue 4 442-443 
Larkin M.No abstract available
Veterinary students’ attitudes on One Health: implications for curriculum development at veterinary colleges.
Journal of veterinary medical education    March 12, 2013   Volume 40, Issue 1 58-62 doi: 10.3138/jvme.0612.057R
Wong D, Kogan LR.One Health knowledge has been identified by the North American Veterinary Medical Education Consortium (NAVMEC) as a core competency for all graduating veterinarians. Many veterinary colleges, however, are still in the preliminary stages of exploring how best to incorporate One Health principles into their existing curricula. In February 2012, we conducted a survey among second to fourth-year Professional Veterinary Medicine (PVM) students at the Colorado State University College of Veterinary Medicine and Biomedical Sciences to assess One Health needs and attitudes. Out of 407 students, 93 (2...
Lessons of history in veterinary medicine.
Journal of veterinary medical education    March 9, 2013   Volume 40, Issue 1 2-11 doi: 10.3138/jvme.1112.04
Smith DF.The future of veterinary medicine is best understood in the context of history. What began as a profession rooted in urban centers in proximity to horses, physicians, and medical schools, was transformed into a land grant-based agricultural profession with the arrival of the internal combustion engine in the early twentieth century. Most of the United States' current veterinary colleges are still located in towns or small cities in the middle section of the country, outside the largest metropolitan areas where most veterinarians practice companion-animal medicine. Throughout veterinarian histo...
Contracted foal syndrome associated with multiple malformations in two foals.
Anatomia, histologia, embryologia    February 14, 2013   Volume 43, Issue 1 71-74 doi: 10.1111/ahe.12030
Binanti D, Zani DD, De Zani D, Turci T, Zavaglia G, Riccaboni P.Congenital anomalies in horses are very rare, and contracted foal syndrome is one of the most commonly reported. This malformation is characterized by contraction of the joints of the forelimbs and/or hindlimbs. In addition, the syndrome can be characterized by vertebral column malformations, such as scoliosis or torticollis, and cranial deformity. The present report describes the radiological and necroscopical findings of multiple rare malformations in two foals. Both foals showed skeletal abnormalities and fenestration of the abdominal cavity. Other pathological findings include a interventr...
Renin-Angiotensin-aldosterone system and hypothalamic-pituitary-adrenal axis in hospitalized newborn foals.
Journal of veterinary internal medicine    February 11, 2013   Volume 27, Issue 2 331-338 doi: 10.1111/jvim.12043
Dembek KA, Onasch K, Hurcombe SD, MacGillivray KC, Slovis NM, Barr BS, Reed SM, Toribio RE.The renin-angiotensin-aldosterone system (RAAS) and hypothalamic-pituitary-adrenal axis (HPAA) and their interactions during illness and hypoperfusion are important to maintain organ function. HPAA dysfunction and relative adrenal insufficiency (RAI) are common in septic foals. Information is lacking on the RAAS and mineralocorticoid response in the context of RAI in newborn sick foals. Objective: To investigate the RAAS, as well as HPAA factors that interact with the RAAS, in hospitalized foals, and to determine their association with clinical findings. We hypothesized that critical illness i...
A systematic review of the immune-modulators Parapoxvirus ovis and Propionibacterium acnes for the prevention of respiratory disease and other infections in the horse.
Veterinary immunology and immunopathology    February 5, 2013   Volume 153, Issue 1-2 1-9 doi: 10.1016/j.vetimm.2013.01.010
Paillot R.Inactivated Parapoxvirus ovis (iPPVO) and Propionibacterium acnes (P. acnes) are currently used in equine medicine as immune-modulators for prophylactic treatment or adjunct to conventional therapy in order to improve immune defences, to prevent or treat infectious diseases. Their mode of action relies on a non-antigen specific interaction with the innate and/or adaptive immune responses. iPPVO stimulates and regulates cytokine secretion by leucocytes, while P. acnes acts primarily through the activation of macrophages. This report aims to describe their activity as immune-modulators and to su...
Oleander toxicosis in equids: 30 cases (1995-2010).
Journal of the American Veterinary Medical Association    February 1, 2013   Volume 242, Issue 4 540-549 doi: 10.2460/javma.242.4.540
Renier AC, Kass PH, Magdesian KG, Madigan JE, Aleman M, Pusterla N.To determine clinical, laboratory analysis, and necropsy findings for equids with oleander toxicosis and to identify factors associated with outcome. Methods: Retrospective case series. Methods: 30 equids. Methods: Medical records of equids with detectable concentrations of oleandrin in serum, plasma, urine, or gastrointestinal fluid samples and equids that had not received cardiac glycoside drugs but had detectable concentrations of digoxin in serum were identified via a medical records database search. Descriptive statistics were calculated for medical history, physical examination, laborato...
Respiratory diseases and their effects on respiratory function and exercise capacity.
Equine veterinary journal    February 1, 2013   Volume 45, Issue 3 376-387 doi: 10.1111/evj.12028
Van Erck-Westergren E, Franklin SH, Bayly WM.Given that aerobic metabolism is the predominant energy pathway for most sports, the respiratory system can be a rate-limiting factor in the exercise capacity of fit and healthy horses. Consequently, respiratory diseases, even in mild forms, are potentially deleterious to any athletic performance. The functional impairment associated with a respiratory condition depends on the degree of severity of the disease and the equestrian discipline involved. Respiratory abnormalities generally result in an increase in respiratory impedance and work of breathing and a reduced level of ventilation that c...
Effects of compressive abdominal bandaging and transrectal palpation on intra-abdominal pressures in horses.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    January 30, 2013   Volume 23, Issue 1 41-46 doi: 10.1111/j.1476-4431.2012.00827.x
Barrett EJ, Munsterman AS, Hanson RR.To determine the effect of an abdominal support wrap and transrectal abdominal palpation on intra-abdominal pressures (IAPs) measured directly from the peritoneal space. Methods: Prospective, experimental study. Methods: A university-based equine research facility. Methods: Ten healthy adult horses, 5 males and 5 females. Methods: IAPs were measured through an intraperitoneal cannula zeroed at a height midway between the height of the tuber ishii and point of the shoulder. Triplicate measurements were obtained at rest, during transrectal palpation, after placement of an abdominal support wrap,...
Cardiac output monitoring in horses.
The Veterinary clinics of North America. Equine practice    January 17, 2013   Volume 29, Issue 1 155-167 doi: 10.1016/j.cveq.2012.11.002
Shih A.Cardiac output (CO) is the volume of blood pumped out by the heart in 1 minute. Monitoring of CO can guide therapy and improve clinical outcome in critically ill patients and during anesthesia. Although there is increasing research into clinically useful methods of monitoring CO in equine patients, there are limitations to the available methods. There are 4 basic methods of measuring CO: (1) indicator methods, (2) a derivation of the Fick principle, (3) arterial pulse wave analysis, and (4) imaging diagnostic techniques. This article discusses the importance of CO, available technology, and ch...
Magnetic resonance protocols in equine lameness examination, used sequences, and interpretation.
Polish journal of veterinary sciences    January 1, 2013   Volume 16, Issue 4 803-811 doi: 10.2478/pjvs-2013-0115
Jaskólska M, Adamiak Z, Zhalniarovich Y, Holak P, Przyborowska P.Magnetic resonance is a great diagnostic tool in equine lameness examination. Its value is most significantly visible in evaluating distal extremities. Problems with podotrochlear apparatus, laminitis or distal interphalangeal joint osteoarthritis are the most common disorders diagnosed in equine patients. Without using magnetic resonance it was impossible to clearly assess which structures are involved in each of these diseases. One of the most important things in MRI is the choice of sequence. Most commonly used are T1 GE, T2 FSE, STIR and T2* GE, in sagittal, transverse and dorsal planes. T...
Advances in equine imaging.
The Veterinary clinics of North America. Equine practice    November 28, 2012   Volume 28, Issue 3 xiii-xiv doi: 10.1016/j.cveq.2012.09.006
Werpy NM, Barrett MF.No abstract available
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