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Topic:Equine Science

Equine Science encompasses the study of horses and their management, health, and performance. This field integrates various scientific disciplines such as biology, genetics, nutrition, physiology, and veterinary medicine to understand and improve the well-being and capabilities of horses. Areas of focus include equine anatomy, reproduction, behavior, and disease prevention. Research in equine science aims to enhance horse care, optimize training and performance, and address health challenges. This page compiles peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine science, providing insights into the latest advancements and methodologies in the field.
Faecal microbiota of forage-fed horses in New Zealand and the population dynamics of microbial communities following dietary change.
PloS one    November 10, 2014   Volume 9, Issue 11 e112846 doi: 10.1371/journal.pone.0112846
Fernandes KA, Kittelmann S, Rogers CW, Gee EK, Bolwell CF, Bermingham EN, Thomas DG.The effects of abrupt dietary transition on the faecal microbiota of forage-fed horses over a 3-week period were investigated. Yearling Thoroughbred fillies reared as a cohort were exclusively fed on either an ensiled conserved forage-grain diet ("Group A"; n = 6) or pasture ("Group B"; n = 6) for three weeks prior to the study. After the Day 0 faecal samples were collected, horses of Group A were abruptly transitioned to pasture. Both groups continued to graze similar pasture for three weeks, with faecal samples collected at 4-day intervals. DNA was isolated from the faeces and microbial 16S ...
Augmenting reality in anatomy.
The Veterinary record    November 8, 2014   Volume 175, Issue 18 444 doi: 10.1136/vr.g6637
No abstract available
Calcium-sensing receptor-mediated osteogenic and early-stage neurogenic differentiation in umbilical cord matrix mesenchymal stem cells from a large animal model.
PloS one    November 7, 2014   Volume 9, Issue 11 e111533 doi: 10.1371/journal.pone.0111533
Umbilical cord matrix mesenchymal stem cells (UCM-MSCs) present a wide range of potential therapeutical applications. The extracellular calcium-sensing receptor (CaSR) regulates physiological and pathological processes. We investigated, in a large animal model, the involvement of CaSR in triggering osteogenic and neurogenic differentiation of two size-sieved UCM-MSC lines, by using AMG641, a novel potent research calcimimetic acting as CaSR agonist. Results: Large (>8 µm in diameter) and small (<8 µm) equine UCM-MSC lines were cultured in medium with high calcium (Ca2+) concentration (...
Infectious diseases of working equids.
The Veterinary clinics of North America. Equine practice    November 6, 2014   Volume 30, Issue 3 695-718 doi: 10.1016/j.cveq.2014.09.001
Stringer AP.Most working equids reside in low-income countries where they have an essential role in the livelihoods of their owners. Numerous infectious diseases negatively impact the health and productivity of these animals. There are considerable technical, social-behavioral, and institutional impediments globally to reducing the burden of infectious diseases on working equids. One the greatest remaining challenges is the lack of funding for research, resulting from the low priority assigned to working equids by funding bodies. Changing the attitudes of decision makers will require data-driven advocacy,...
HORSE SPECIES SYMPOSIUM: The aging horse: Effects of inflammation on muscle satellite cells.
Journal of animal science    November 5, 2014   Volume 93, Issue 3 862-870 doi: 10.2527/jas.2014-8448
Reed SA, LaVigne EK, Jones AK, Patterson DF, Schauer AL.With improvements in care, the equine population is living longer, remaining active, and competing at increasingly older ages. Both advancing age and exercise result in increased concentrations of circulating and local cytokines, including IL-1β, IL-6, and tumor necrosis factor-α. Athletic endeavors in the aged horse may further increase the proinflammatory environment in muscle, decreasing the ability to react appropriately to exercise. Poor response to exercise limits the athletic ability of geriatric horses, thus reducing their useful life span and potentially increasing the risk of injur...
Use of hypometabolic TRIS extenders and high cooling rate refrigeration for cryopreservation of stallion sperm: presence and sensitivity of 5′ AMP-activated protein kinase (AMPK).
Cryobiology    November 3, 2014   Volume 69, Issue 3 473-481 doi: 10.1016/j.cryobiol.2014.10.008
Córdova A, Strobel P, Vallejo A, Valenzuela P, Ulloa O, Burgos RA, Menarim B, Rodríguez-Gil JE, Ratto M, Ramírez-Reveco A.This study evaluated the effect of the use of hypometabolic TRIS extenders in the presence or the absence of AMPK activators as well as the utilization of high cooling rates in the refrigeration step on the freezability of stallion sperm. Twelve ejaculates were cryopreserved using Botucrio® as a control extender and a basic TRIS extender (HM-0) separately supplemented with 10 mM metformin, 2mM 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR), 2 mM Adenosine monophosphate (AMP), 40 μM compound C AMPK inhibitor or 2 mM AMP+40 μM compound C. Our results showed that the utilization ...
Esophageal Dysfunction in Friesian Horses: Morphological Features.
Veterinary pathology    November 3, 2014   Volume 52, Issue 6 1142-1147 doi: 10.1177/0300985814556780
Ploeg M, Gröne A, Saey V, de Bruijn CM, Back W, van Weeren PR, Scheideman W, Picavet T, Ducro BJ, Wijnberg I, Delesalle C.Megaesophagus appears to be more common in Friesian horses than in other breeds. A prevalence of approximately 2% was observed among Friesian horses presented to the Wolvega Equine Clinic and the Utrecht University Equine Clinic. In this study, morphologic changes in the esophagi of Friesian horses with megaesophagus were compared with those of 6 control horses. Of 18 horses with clinically observed megaesophagus, only 12 animals had esophageal dilation at necropsy, usually involving the thoracic portion. Muscular hypertrophy of the distal esophagus was present in only one-third of the affecte...
Modelling the equine hindgut.
The Veterinary record    November 2, 2014   Volume 175, Issue 17 421 doi: 10.1136/vr.g6509
No abstract available
Effects of topical application of misoprostol on cervical relaxation in mares.
Reproduction in domestic animals = Zuchthygiene    November 1, 2014   Volume 49, Issue 6 1057-1062 doi: 10.1111/rda.12435
McNaughten J, Pozor M, Macpherson M, Kelleman A, Woodward E, Troedsson M.Mares who have not delivered a foal early in life may experience limitations in cervical relaxation, primarily during oestrus. A closed cervix prevents intrauterine deposition of semen during natural breeding, may delay uterine clearance after insemination leading to intrauterine fluid accumulation in, and subsequent infertility. Therefore, a reliable pharmacological method of dilating the equine cervix would have practical application in veterinary medicine. The goal of this study was to investigate the effectiveness of topically applied, synthetic prostaglandin E1 analogue (PGE1 ) for stimul...
Application of a novel sorting system for equine mesenchymal stem cells (MSCs).
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire    October 31, 2014   Volume 78, Issue 4 290-296 
Radtke CL, Nino-Fong R, Esparza Gonzalez BP, McD○ LA.The objective of this study was to validate non-equilibrium gravitational field-flow fractionation (GrFFF), an immunotag-less method of sorting mesenchymal stem cells (MSCs) into subpopulations, for use with MSCs derived from equine muscle tissue, periosteal tissue, bone marrow, and adipose tissue. Cells were collected from 6 young, adult horses, postmortem. Cells were isolated from left semitendinosus muscle tissue, periosteal tissue from the distomedial aspect of the right tibia, bone marrow aspirates from the fourth and fifth sternebrae, and left supragluteal subcutaneous adipose tissue. Al...
Animal-assisted therapy with chronic psychiatric inpatients: equine-assisted psychotherapy and aggressive behavior.
Psychiatric services (Washington, D.C.)    October 31, 2014   Volume 66, Issue 1 80-86 doi: 10.1176/appi.ps.201300524
Nurenberg JR, Schleifer SJ, Shaffer TM, Yellin M, Desai PJ, Amin R, Bouchard A, Montalvo C.Animal-assisted therapy (AAT), most frequently used with dogs, is being used increasingly as an adjunctive alternative treatment for psychiatric patients. AAT with larger animals, such as horses, may have unique benefits. In this randomized controlled study, equine and canine forms of AAT were compared with standard treatments for hospitalized psychiatric patients to determine AAT effects on violent behavior and related measures. Methods: The study included 90 patients with recent in-hospital violent behavior or highly regressed behavior. Hospitalization at the 500-bed state psychiatric hospit...
Ossification of ungular cartilages in front feet of cold-blooded trotters–a clinical radiographic evaluation of development over time.
Acta veterinaria Scandinavica    October 30, 2014   Volume 56, Issue 1 73 doi: 10.1186/s13028-014-0073-z
Hedenström UO, Olsson U, Holm AW, Wattle OS.It has not yet been shown that ossification of ungular cartilages (OUC) is a pathological condition. Beside heredity, factors such as sex, age, repeated concussion, local trauma, hoof and body size have been suggested as contributing factors for OUC development. By comparing radiographs of front hooves from cold-blooded trotters with different age we wanted to evaluate when development of OUC in cold-blooded trotters occurs and if and when it stabilizes in relation to age and workload. Diagnosis and grading of OUC were based on radiological field examinations of 649 Swedish and Norwegian cold-...
Saving energy during hard times: energetic adaptations of Shetland pony mares.
The Journal of experimental biology    October 30, 2014   Volume 217, Issue Pt 24 4320-4327 doi: 10.1242/jeb.111815
Brinkmann L, Gerken M, Hambly C, Speakman JR, Riek A.Recent results suggest that wild Northern herbivores reduce their metabolism during times of low ambient temperature and food shortage in order to reduce their energetic needs. It is, however, not known whether domesticated animals are also able to reduce their energy expenditure. We exposed 10 Shetland pony mares to different environmental conditions (summer and winter) and to two food quantities (60% and 100% of maintenance energy requirement) during low winter temperatures to examine energetic and behavioural responses. In summer, ponies showed a considerably higher field metabolic rate (FM...
Evaluation of ultrasmall superparamagnetic iron oxide contrast agent labeling of equine cord blood and bone marrow mesenchymal stromal cells.
American journal of veterinary research    October 29, 2014   Volume 75, Issue 11 1010-1017 doi: 10.2460/ajvr.75.11.1010
Bourzac CA, Koenig JB, Link KA, Nykamp SG, Koch TG.To evaluate the efficacy and effects of labeling equine umbilical cord blood (UCB)- and bone marrow (BM)-derived multipotent mesenchymal stromal cells (MSCs) with an ultrasmall superparamagnetic iron oxide (SPIO) contrast agent and the detection of labeled MSCs by use of MRI. Methods: UCB MSCs from placental tissues of 5 foals and BM MSCs from 5 horses. Methods: UCB and BM MSC cultures were seeded in duplicate (5,000 cells/cm(2)). One duplicate was incubated with SPIO (50 μg/mL); the other was processed identically, but without SPIO. Mesenchymal stromal cells were expanded in triplicates for ...
Andrographolide Exerts Chondroprotective Activity in Equine Cartilage Explant and Suppresses Interleukin-1 β -Induced MMP-2 Expression in Equine Chondrocyte Culture.
International scholarly research notices    October 29, 2014   Volume 2014 464136 doi: 10.1155/2014/464136
Tangyuenyong S, Viriyakhasem N, Peansukmanee S, Kongtawelert P, Ongchai S.Cartilage erosion in degenerative joint diseases leads to lameness in affected horses. It has been reported that andrographolide from Andrographis paniculata inhibited cartilage matrix-degrading enzymes. This study aimed to explore whether this compound protects equine cartilage degradation in the explant culture model and to determine its effect on matrix metalloproteinase-2 (MMP-2) expression, a matrix-degrading enzyme, in equine chondrocyte culture. Equine articular cartilage explant culture was induced by 25 ng/mL interleukin-1β, a key inducer of cartilage degeneration, in cultures with...
Equine model for soft-tissue regeneration.
Journal of biomedical materials research. Part B, Applied biomaterials    October 28, 2014   Volume 103, Issue 6 1217-1227 doi: 10.1002/jbm.b.33299
Bellas E, Rollins A, Moreau JE, Lo T, Quinn KP, Fourligas N, Georgakoudi I, Leisk GG, Mazan M, Thane KE, Taeymans O, Hoffman AM, Kaplan DL....Soft-tissue regeneration methods currently yield suboptimal clinical outcomes due to loss of tissue volume and a lack of functional tissue regeneration. Grafted tissues and natural biomaterials often degrade or resorb too quickly, while most synthetic materials do not degrade. In previous research we demonstrated that soft-tissue regeneration can be supported using silk porous biomaterials for at least 18 months in vivo in a rodent model. In the present study, we scaled the system to a survival study using a large animal model and demonstrated the feasibility of these biomaterials for soft-tis...
BEVA seeks to dispel confusion about equine dental procedures.
The Veterinary record    October 26, 2014   Volume 175, Issue 16 393 doi: 10.1136/vr.g6313
No abstract available
Ex vivo evaluation of carpal flexion after partial carpal arthrodesis in horses.
Veterinary surgery : VS    October 25, 2014   Volume 44, Issue 3 386-391 doi: 10.1111/j.1532-950X.2014.12299.x
Tulloch PJ, Johnston JD, Barber SM, Gellert CL, Lang HM, Panizzi L.To determine degrees of flexion after arthrodesis of the antebrachiocarpal (ABC) joint, middle carpal (MC), and carpometacarpal (CMC) joints combined (MC/CMC), and carpometacarpal (CMC) joint alone. Methods: Ex vivo study. Methods: Forelimbs (n = 9) from 2- to 10-year-old Quarter Horses (5), Thoroughbred (2), and American Paint Horse (2). Methods: Using 2 locking compression plates, 3 partial carpal arthrodesis techniques were performed. Cables and deadweights were connected to limbs and each angle of flexion determined 3 times using a protractor and then averaged. Control measurements were ob...
Validation study of an interpolation method for calculating whole lung volumes and masses from reduced numbers of CT-images in ponies.
Veterinary journal (London, England : 1997)    October 22, 2014   Volume 202, Issue 3 603-607 doi: 10.1016/j.tvjl.2014.10.019
Reich H, Moens Y, Braun C, Kneissl S, Noreikat K, Reske A.Quantitative computer tomographic analysis (qCTA) is an accurate but time intensive method used to quantify volume, mass and aeration of the lungs. The aim of this study was to validate a time efficient interpolation technique for application of qCTA in ponies. Forty-one thoracic computer tomographic (CT) scans obtained from eight anaesthetised ponies positioned in dorsal recumbency were included. Total lung volume and mass and their distribution into four compartments (non-aerated, poorly aerated, normally aerated and hyperaerated; defined based on the attenuation in Hounsfield Units) were de...
Discovery and comparative analysis of a novel satellite, EC137, in horses and other equids.
Cytogenetic and genome research    October 21, 2014   Volume 144, Issue 2 114-123 doi: 10.1159/000368138
Nergadze SG, Belloni E, Piras FM, Khoriauli L, Mazzagatti A, Vella F, Bensi M, Vitelli V, Giulotto E, Raimondi E.Centromeres are the sites of kinetochore assembly and spindle fiber attachment and consist of protein-DNA complexes in which the DNA component is typically characterized by the presence of extended arrays of tandem repeats called satellite DNA. Here, we describe the isolation and characterization of a 137-bp-long new satellite DNA sequence from the horse genome (EC137), which is also present, even if less abundant, in the domestic donkey, the Grevy's zebra and the Burchelli's zebra. We investigated the chromosomal distribution of the EC137 sequence in these 4 species. Moreover, we analyzed its...
Mitochondrial DNA lineages of Italian Giara and Sarcidano horses.
Genetics and molecular research : GMR    October 20, 2014   Volume 13, Issue 4 8241-8257 doi: 10.4238/2014.October.20.1
Giara and Sarcidano are 2 of the 15 extant native Italian horse breeds with limited dispersal capability that originated from a larger number of individuals. The 2 breeds live in two distinct isolated locations on the island of Sardinia. To determine the genetic structure and evolutionary history of these 2 Sardinian breeds, the first hypervariable segment of the mitochondrial DNA (mtDNA) was sequenced and analyzed in 40 Giara and Sarcidano horses and compared with publicly available mtDNA data from 43 Old World breeds. Four different analyses, including genetic distance, analysis of molecular...
Effects of handling on fear reactions in young Icelandic horses.
Equine veterinary journal    October 19, 2014   Volume 47, Issue 5 615-619 doi: 10.1111/evj.12338
Marsbøll AF, Christensen JW.Inclusion of objective temperament tests at practical horse breeding evaluations is of increased interest. It has been debated whether such tests may involve human handling, since there may be considerable differences in horses' handling experience. Objective: To investigate the effect of a short-term standardised handling procedure on reactions of young horses in 2 types of fear tests (including and excluding human handling). Methods: An experimental study with 3-year-old Icelandic horses (n = 24). Methods: Handled horses (n = 12) were trained according to a standardised handling procedure wh...
Upflow anaerobic solid-state (UASS) digestion of horse manure: Thermophilic vs. mesophilic performance.
Bioresource technology    October 18, 2014   Volume 175 8-16 doi: 10.1016/j.biortech.2014.10.041
Böske J, Wirth B, Garlipp F, Mumme J, Van den Weghe H.Energetic use of complex lignocellulosic wastes has gained global interest. Thermophilic digestion of horse manure based on straw was investigated using the upflow anaerobic solid-state (UASS) process. Increasing the organic loading rate from 2.5 to 5.5gvsL(-)(1)d(-)(1) enhanced the average methane production rate from 0.387 to 0.687LCH4L(-)(1)d(-)(1), whereas the yield decreased from 154.8 to 124.8LCH4kgvs(-)(1). A single-stage and two-stage process design showed almost the same performance. Compared to prior experiments at mesophilic conditions, thermophilic conditions showed a significantly...
Science in brief: Report from the Seventh International Colloquium on Working Equids, London 2014.
Equine veterinary journal    October 17, 2014   Volume 46, Issue 6 768-770 doi: 10.1111/evj.12343
Compston P.No abstract available
Science in brief: Report on the Havemeyer Foundation workshop on equine musculoskeletal biomarkers–current knowledge and future needs.
Equine veterinary journal    October 17, 2014   Volume 46, Issue 6 651-653 doi: 10.1111/evj.12339
McIlwraith CW, Clegg PD.No abstract available
The contribution of donkeys to human health.
Equine veterinary journal    October 17, 2014   Volume 46, Issue 6 766-767 doi: 10.1111/evj.12337
Ali M, Baber M, Hussain T, Awan F, Nadeem A.No abstract available
World Horse Welfare online collection of research on working equids.
Equine veterinary journal    October 17, 2014   Volume 46, Issue 6 764-765 doi: 10.1111/evj.12342
Owers R, Marr C.No abstract available
Postural characteristics of female dressage riders using 3D motion analysis and the effects of an athletic taping technique: A randomised control trial.
Physical therapy in sport : official journal of the Association of Chartered Physiotherapists in Sports Medicine    October 16, 2014   Volume 16, Issue 2 154-161 doi: 10.1016/j.ptsp.2014.09.005
Alexander J, Hobbs SJ, May K, Northrop A, Brigden C, Selfe J.To observe postural characteristics of female dressage riders, through application of three-dimensional motion analysis and to assess the effects of athletic taping on postural asymmetry during sitting trot. Methods: Randomised cross-over. Methods: Data collection took place at Myerscough Agricultural College in an indoor riding area. Methods: Ten healthy female experienced dressage riders participated. Methods: Movement kinematics of the trunk and pelvis, pre and post taping intervention. Results: Riders presented pre-intervention with asymmetric movement characteristics through dynamic obser...
Behind the vertical and behind the times.
Veterinary journal (London, England : 1997)    October 13, 2014   Volume 202, Issue 3 403-404 doi: 10.1016/j.tvjl.2014.10.005
König von Borstel U, McGreevy PD.No abstract available
Localization and functional modification of L-type voltage-gated calcium channels in equine spermatozoa from fresh and frozen semen.
Theriogenology    October 13, 2014   Volume 83, Issue 3 421-429 doi: 10.1016/j.theriogenology.2014.10.005
Albrizio M, Moramarco AM, Nicassio M, Micera E, Zarrilli A, Lacalandra GM.It is well known that insemination of cryopreserved semen always results in lower fertility when compared with fresh semen, but there is an increased interest and demand for frozen equine semen by the major breeder associations because of the utility arising from semen already "on hand" at breeding time. In this article, we report that equine sperm cells express L-type voltage-gated calcium channels; their localization is restricted to sperm neck and to the principal piece of the tail in both fresh and frozen-thawed spermatozoa. We also studied the causes of cryoinjury at the membrane level fo...