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Topic:Equine Science

Equine Science encompasses the study of horses and their management, health, and performance. This field integrates various scientific disciplines such as biology, genetics, nutrition, physiology, and veterinary medicine to understand and improve the well-being and capabilities of horses. Areas of focus include equine anatomy, reproduction, behavior, and disease prevention. Research in equine science aims to enhance horse care, optimize training and performance, and address health challenges. This page compiles peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine science, providing insights into the latest advancements and methodologies in the field.
Developments in European horse breeding and consequences for veterinarians in equine reproduction.
Reproduction in domestic animals = Zuchthygiene    July 28, 2006   Volume 41, Issue 4 275-279 doi: 10.1111/j.1439-0531.2006.00719.x
Aurich J, Aurich C.The liberalization of European animal breeding legislation and an increasing diversity of equestrian sports have led to a constant rise in the number of horse breeds and breed registries. In addition to the trend towards more and smaller breed registries, there is another trend towards an international expansion of the bigger established sport horse breeds. Regional breeds, at least in smaller countries, may no longer be able to run an independent breeding programme. The typical horse breeder, in the future, will be a female and qualified in equestrian sports. Artificial insemination (AI) main...
Knowledge of the equine temporomandibular joint.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 361 
Cook WR.No abstract available
Measurement of abnormal respiratory sounds during over-ground exercise.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 319-323 
Burn JF, Franklin SH.The presence of abnormal respiratory sounds is commonly associated with obstructions of the upper respiratory tract. In order to establish their clinical significance measurements are required of both normal and abnormal respiratory sounds produced by horses exercising over-ground. Objective: To determine whether high quality recordings of respiratory sound can be made during over-ground exercise, and to develop a convenient measurement system that can be used to obtain respiratory sounds from horses exercising in field conditions. Methods: A range of prototypes was evaluated against the requi...
The modified Meek technique as a novel method for skin grafting in horses: evaluation of acceptance, wound contraction and closure in chronic wounds.
Equine veterinary journal    July 27, 2006   Volume 38, Issue 4 324-329 doi: 10.2746/042516406777749290
Wilmink JM, van den Boom R, van Weeren PR, Barneveld A.The acceptance of skin grafts in horses is unpredictable and the final cosmetic result can be disappointing. Besides movement and infection, graft failure is often caused by chronic inflammation, inherently present during second intention healing of limb wounds in horses. In human burns affected by infection and inflammation, the acceptance of the island skin grafts of the modified Meek technique appeared to be better than meshed sheet skin grafts. Objective: The percentage take of Meek micrografts is higher than of other techniques; and rates of both wound contraction and epithelialisation ar...
Is equine therapy useful in the treatment of eating disorders?
Eating disorders    July 26, 2006   Volume 11, Issue 2 143-147 doi: 10.1080/10640260390199325
Cumella EJ.No abstract available
A preliminary study on the induction of dioestrous ovulation in the mare–a possible method for inducing prolonged luteal phase.
Acta veterinaria Scandinavica    July 26, 2006   Volume 48, Issue 1 12 doi: 10.1186/1751-0147-48-12
Hedberg Y, Dalin AM, Santesson M, Kindahl H.Strong oestrous symptoms in the mare can cause problems with racing, training and handling. Since long-acting progesterone treatment is not permitted in mares at competition (e.g. according to FEI rules), there is a need for methods to suppress unwanted cyclicity. Spontaneous dioestrous ovulations in the late luteal phase may cause a prolongation of the luteal phase in mares. Methods: In this preliminary study, in an attempt to induce ovulation during the luteal phase, human chorionic gonadotropin (hCG) (3000 IU) was injected intramuscularly in four mares (experimental group) in the luteal pha...
Rapid test by liquid chromatography/tandem mass spectrometry to evaluate equine urine reactivity towards 17beta-OH steroids.
Rapid communications in mass spectrometry : RCM    July 25, 2006   Volume 20, Issue 16 2441-2446 doi: 10.1002/rcm.2608
Fidani M, Casagni E, Montana M, Pasello E, Pecoraro C, Gambaro V.Bacteria frequently found in equine urine samples may cause degradation of 17beta-OH steroids. A simple liquid chromatography/tandem mass spectrometry (LC/MS/MS) method has been developed to evaluate the microbiological contamination of equine urine as a marker of poor storage conditions. Norethandrolone was used as the internal standard, and the linearity, sensitivity, precision and accuracy of the method were evaluated. 17beta-OH oxidation was demonstrated for testosterone, nandrolone, trenbolone and boldenone, but did not occur in alpha-epimers such as alpha-boldenone and epitestosterone, d...
The influence of collagen fiber orientation and other histocompositional characteristics on the mechanical properties of equine cortical bone.
The Journal of experimental biology    July 22, 2006   Volume 209, Issue Pt 15 3025-3042 doi: 10.1242/jeb.02304
Skedros JG, Dayton MR, Sybrowsky CL, Bloebaum RD, Bachus KN.This study examined relative influences of predominant collagen fiber orientation (CFO), mineralization (% ash), and other microstructural characteristics on the mechanical properties of equine cortical bone. Using strain-mode-specific (S-M-S) testing (compression testing of bone habitually loaded in compression; tension testing of bone habitually loaded in tension), the relative mechanical importance of CFO and other material characteristics were examined in equine third metacarpals (MC3s). This model was chosen since it had a consistent non-uniform strain distribution estimated by finite ele...
Derivation, maintenance, and induction of the differentiation in vitro of equine embryonic stem cells.
Methods in molecular biology (Clifton, N.J.)    July 19, 2006   Volume 329 59-79 doi: 10.1385/1-59745-037-5:59
Saito S, Sawai K, Minamihashi A, Ugai H, Murata T, Yokoyama KK.We describe here the isolation and maintenance of pluripotent embryonic stem (ES) cells from equine blastocysts that have been frozen and thawed. Equine ES cells appear to maintain a normal diploid karyotype in culture. These cells express markers that are characteristic of mouse ES cells, namely, alkaline phosphatase, stage-specific-embryonic antigen 1, STAT3, and Oct4. We also describe protocols for the induction of differentiation in vitro to neural precursor cells in the presence of basic fibroblast growth factor (bFGF), epidermal growth factor, and platelet-derived growth factor and to he...
Cloning and pharmacological characterization of the equine adenosine A3 receptor.
Journal of veterinary pharmacology and therapeutics    July 19, 2006   Volume 29, Issue 4 255-263 doi: 10.1111/j.1365-2885.2006.00748.x
Brandon CI, Vandenplas M, Dookwah H, Murray TF.The aim of this study was to establish a heterologous expression system for the equine adenosine A(3) receptor (eA(3)-R) in an effort to ascertain its pharmacologic profile. Initially, radioligand binding assays identified clones expressing the eA(3)-R in human embryonic kidney cells (HEK) based on the specific binding of [(125)I]AB-MECA. Subsequently, adenylate cyclase assays were utilized to demonstrate functional coupling of the eA(3)-R to the G-protein/adenylate cyclase system. Equilibrium competition binding assays were then performed using selective and non-selective A(3) agonists and an...
Theriogenology question of the month. Large ossified remnant of the yolk sac.
Journal of the American Veterinary Medical Association    July 18, 2006   Volume 229, Issue 2 215-217 doi: 10.2460/javma.229.2.215
Harbo JM, Mausling RD, Schlafer DH, Vanderwall DK.No abstract available
Conformation of the equine skull: a morphometric study.
Anatomia, histologia, embryologia    July 14, 2006   Volume 35, Issue 4 221-227 doi: 10.1111/j.1439-0264.2005.00663.x
Evans KE, McGreevy PD.There is a lack of an established method for quantifying equine skull morphology. This study proposes a method that is valid for use on both live and deceased horses. A total of nine head measurements (skull length, cranial length, nasal length, ratio of cranial:nasal length, cranial width, zygomatic width, mandibular depth, nasal profile area, cranial profile area) and six indices (skull index, cranial index, nasal index, mandibular index, nasal profile index, cranial profile index) were recorded from 30 horses from a variety of breeds whilst the soft tissues of the head were intact. A line w...
Absence of hyaline cartilage in the tongue of ‘Caspian miniature horse’.
Anatomia, histologia, embryologia    July 14, 2006   Volume 35, Issue 4 241-246 doi: 10.1111/j.1439-0264.2005.00673.x
Rezaian M.Histology of the tongue, including apex, root and body, in four adult Caspian miniature horses was examined. Serial sections with 6 mum thickness were stained with haematoxylin-eosin and Masson trichrome and studied under light microscope. The tongue was covered by stratified squamous epithelium. It was thick and keratinized bearing numerous lingual papillae on the dorsum, mostly filiform with a very fine keratinized thread projecting above the surface and bending backward. The fungiform papillae were sparsely scattered among the filiform papillae and covered with keratinized squamous epitheli...
Three-dimensional optic axis determination using variable-incidence-angle polarization-optical coherence tomography.
Optics letters    July 13, 2006   Volume 31, Issue 15 2305-2307 doi: 10.1364/ol.31.002305
Ugryumova N, Gangnus SV, Matcher SJ.Polarization optical coherence tomography (PSOCT) is a powerful technique to nondestructively map the retardance and fast-axis orientation of birefringent biological tissues. Previous studies have concentrated on the case where the optic axis lies on the plane of the surface. We describe a method to determine the polar angle of the optic axis of a uniaxial birefringent tissue by making PSOCT measurements with a number of incident illumination directions. The method is validated on equine flexor tendon, yielding a variability of 4% for the true birefringence and 3% for the polar angle. We use t...
Climatic influences on development and survival of free-living stages of equine strongyles: implications for worm control strategies and managing anthelmintic resistance.
Veterinary journal (London, England : 1997)    July 11, 2006   Volume 174, Issue 1 23-32 doi: 10.1016/j.tvjl.2006.05.009
Nielsen MK, Kaplan RM, Thamsborg SM, Monrad J, Olsen SN.Development of resistance to anthelmintic drugs by horse strongyles constitutes a growing threat to equine health because it is unknown when new drug classes can be expected on the market. Consequently, parasite control strategies should attempt to maintain drug efficacy for as long as possible. The proportion of a parasite population that is not exposed to anthelmintic treatment is described as being "in refugia" and although many factors affect the rate at which resistance develops, levels of refugia are considered the most important as these parasites are not selected by treatment and so pr...
Collateral ligaments of the distal sesamoid bone in the digit of Equus: re-evaluating midstance function.
Journal of morphology    July 11, 2006   Volume 267, Issue 10 1177-1185 doi: 10.1002/jmor.10464
Butcher MT, Bertram JE, Benzuidenhout AJ.The distal forelimb of the horse has a complex array of ligaments that play a critical role in determining function of the digit and are often associated with the initiation of foot pathologies. The collateral ligaments of the distal sesamoid bone (CLDS) play an important role in digit stabilization near the end of foot contact and there is also limited evidence to suggest that the CLDS stabilize the proximal interphalangeal joint (PIPJ) during weight bearing. By virtue of their anatomical attachments where the ligaments pass dorsal to the axis of rotation of the PIPJ, it is reasonable to assu...
Molecular cloning and gonadotropin-dependent regulation of equine prostaglandin F2alpha receptor in ovarian follicles during the ovulatory process in vivo.
Prostaglandins & other lipid mediators    July 7, 2006   Volume 80, Issue 1-2 81-92 doi: 10.1016/j.prostaglandins.2006.05.020
Sayasith K, Bouchard N, Doré M, Sirois J.The progressive rise in gonadotropins prior to ovulation triggers a marked increase in intrafollicular levels of prostaglandin F(2alpha)(PGF(2alpha)), which is known to interact with PGF(2alpha) receptor (FP). Little is known about the regulation of FP during ovulation. This study was undertaken to characterize the equine FP and its gonadotropin-dependent regulation in preovulatory follicles prior to ovulation. The full-length equine FP encodes a 366-amino acid protein that is 82-93% homologous to other species. Using semi-quantitative RT-PCR/Southern blot, we showed that FP mRNA expression wa...
Polymorphism identification, RH mapping, and association analysis with the anxiety trait of the equine serotonin transporter (SLC6A4) gene.
The Journal of veterinary medical science    July 6, 2006   Volume 68, Issue 6 619-621 doi: 10.1292/jvms.68.619
Momozawa Y, Takeuchi Y, Tozaki T, Kikusui T, Hasegawa T, Raudsepp T, Chowdhary BP, Kusunose R, Mori Y.Equine anxiety trait is considered an important temperament in various situations, including riding, training, and daily care. This study examined the polymorphism of the equine serotonin transporter (SLC6A4) gene as a candidate genetic element influencing equine anxiety trait. The sequence of the coding region of this gene was highly homologous with those of other mammals, and four single nucleotide polymorphisms were found by comparing the sequences of ten genetically unrelated thoroughbred horses. Radiation hybrid mapping revealed that this gene was located 26.92 cR from neurofibromin 1 on ...
Compensation for changes in hoof conformation between shoeing sessions through the adaptation of angular kinematics of the distal segments of the limbs of horses.
American journal of veterinary research    July 5, 2006   Volume 67, Issue 7 1199-1203 doi: 10.2460/ajvr.67.7.1199
van Heel MC, van Weeren PR, Back W.To determine the mechanism that enables horses to partially counteract the shift of the center of pressure under the hoof induced by changes in hoof morphology attributable to growth and wear during a shoeing interval. Methods: 18 clinically sound Warmblood horses. Methods: Horses were evaluated 2 days and 8 weeks after shoeing during trotting on a track containing pressure-force measuring plates and by use of a synchronous infrared gait analysis system set at a frequency of 240 Hz. All feet were trimmed toward straight alignment of the proximal, middle, and distal phalanges and shod with stan...
Quantification of spontaneous locomotion activity in foals kept in pastures under various management conditions.
American journal of veterinary research    July 5, 2006   Volume 67, Issue 7 1212-1217 doi: 10.2460/ajvr.67.7.1212
Kurvers CM, van Weeren PR, Rogers CW, van Dierendonck MC.To describe spontaneous locomotion activity of foals kept under various management conditions and assess the suitability of global positioning system (GPS) technology for recording foal activity. Animals-59 foals. Methods: During the foals' first 4 months of life, 921 observation periods (15 minutes each) were collected and analyzed for locomotion activities. The GPS system was evaluated by simultaneously carrying out field observations with a handheld computer. Results: Foals spent 0.5% of total observed time cantering, 0.2% trotting, 10.7% walking, 32.0% grazing, 34.8% standing, and 21.6% ly...
Effect of head position on intraocular pressure in horses.
American journal of veterinary research    July 5, 2006   Volume 67, Issue 7 1232-1235 doi: 10.2460/ajvr.67.7.1232
Komáromy AM, Garg CD, Ying GS, Liu C.To evaluate the effect of head position on intraocular pressure (IOP) in horses. Methods: 30 horses. Methods: Horses were sedated with detomidine HCl (0.01 mg/kg, IV). Auriculopalpebral nerve blocks were applied bilaterally with 2% lidocaine HCl. The corneas of both eyes were anesthetized with ophthalmic 0.5% proparacaine solution. Intraocular pressures were measured with an applanation tonometer with the head positioned below and above heart level. The mean of 3 readings was taken for each eye at each position for data analysis. The effect of head position on IOP was assessed and generalized ...
Nucleotide structure of equine platelet-derived growth factor-A and -B and expression in horses with induced acute tendinitis.
American journal of veterinary research    July 5, 2006   Volume 67, Issue 7 1218-1225 doi: 10.2460/ajvr.67.7.1218
Donnelly BP, Nixon AJ, Haupt JL, Dahlgren LA.To characterize the nucleotide sequence of equine platelet-derived growth factor (PDGF)-A and -B and analyze temporal expression of these genes in equine tendon after induced tendinitis injury. Animals-18 mature horses. Methods: Genes for equine PDGF-A and -B were reverse transcribed and sequenced from synovial tissue mRNA obtained from a 3-year-old horse. Collagenase-induced lesions were created in the tensile region of the superficial digital flexor tendon in 14 horses; 3 horses served as uninjured control animals. Tendons were harvested and total RNA was isolated from experimental horses 1,...
Ex vivo comparison of a novel tapered-sleeve and traditional full-limb transfixation pin cast for distal radial fracture stabilization in the horse.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    July 1, 2006   Volume 19, Issue 2 93-97 
Elce YA, Southwood LL, Nutt JN, Nunamaker DM.Distal radial fractures in adult horses are examples of long-bone fractures that are not always amenable to internal fixation. These fractures are often open, contaminated, severely comminuted, and located adjacent to the antebrachiocarpal joint. There have been few studies to improve upon the methods of stabilization of this type of fracture. External coaptation incorporating transfixation pins is one method that has been used to stabilize distal radial fractures in horses (1-3). The purpose of this preliminary study was to compare the load to failure in simulated weight-bearing of a novel ta...
Eastern equine encephalitis–New Hampshire and Massachusetts, August-September 2005.
MMWR. Morbidity and mortality weekly report    July 1, 2006   Volume 55, Issue 25 697-700 
During August-September 2005, the New Hampshire Department of Health and Human Services reported seven cases of human eastern equine encephalitis virus (EEEV) disease, the first laboratory-confirmed, locally acquired cases of human EEEV disease reported from New Hampshire in 41 years of national surveillance. Also during August--September 2005, the Massachusetts Department of Public Health reported four cases of human EEEV disease, five times the annual average of 0.8 cases reported from Massachusetts during the preceding 10 years. Four of the 11 patients from New Hampshire and Massachusetts d...
Morphological evolution and heritability estimates for some biometric traits in the Murgese horse breed.
Genetics and molecular research : GMR    June 30, 2006   Volume 5, Issue 2 309-314 
Dario C, Carnicella D, Dario M, Bufano G.A data set concerning 1,816 subjects entered in the Italian Horse Registry from 1925 to 2002 was analyzed to investigate the morphological evolution of the Murgese horse and to obtain useful elements to enhance breeding practices. Three basic body measurements (height at withers, chest girth, and cannon bone circumference) were considered for each subject. Heritabilities were calculated for each parameter to infer the growth and development traits of this breed. Over the past 20 years the Murgese horse has undergone considerable changes, passing from a typical mesomorphic structure (height at ...
Molecular cross-sectional survey of gastric habronemosis in horses.
Veterinary parasitology    June 23, 2006   Volume 141, Issue 3-4 285-290 doi: 10.1016/j.vetpar.2006.05.021
Traversa D, Iorio R, Capelli G, Paoletti B, Bartolini R, Otranto D, Giangaspero A.Gastric habronemosis of horses caused by Habronema microstoma and Habronema muscae (Nematoda, Spirurida) is characterized by catarrhal gastritis, diarrhoea, progressive weight loss and ulcers. Despite its importance in the equine industry and in clinical practice, knowledge of the epidemiology of this infection is still incomplete as diagnosis in live animals is challenging. A two-step semi-nested PCR assay using ribosomal DNA (rDNA) markers has recently been used for the molecular diagnosis in vivo of gastric habronemosis based on the detection of H. microstoma and/or H. muscae DNA in equine ...
Healing with horses: fostering recovery from cancer with horses as therapists.
Explore (New York, N.Y.)    June 20, 2006   Volume 2, Issue 3 264-268 doi: 10.1016/j.explore.2006.03.013
Haylock PJ, Cantril CA.Nearly 10 years ago, I looked at a poster exhibit for a nonprofit organization's camping experience for cancer survivors. One of the images in particular remains with me to this day. It was of an elderly man wearing a cowboy hat and the great grin on his wrinkled face as he stood next to a beautiful sorrel horse. The woman at the poster told me the story behind the picture: The man had advanced cancer and had already entered a hospice program, even though he was still physically active. He'd told many people that his biggest regret in life was that he'd never gotten to ride a horse. The photog...
Needle electromyographic activity of myofascial trigger points and control sites in equine cleidobrachialis muscle–an observational study.
Acupuncture in medicine : journal of the British Medical Acupuncture Society    June 20, 2006   Volume 24, Issue 2 61-70 doi: 10.1136/aim.24.2.61
Macgregor J, Graf von Schweinitz D.Myofascial trigger points are commonly described in humans, and many studies have shown abnormal spontaneous electrical activity, spike activity and local twitch responses at these sites. Myofascial trigger points have only rarely been described in horses, and studies of their electrophysiological characteristics have not previously been published. The objective of this study was to explore the electromyographic (EMG) and other characteristics of myofascial trigger points in equine muscle, and to compare them with normal muscle tissue. Methods: Four horses with chronic pain signs and impaired ...
Abstracts of the 1st Annual Conference on Network Horse Research in Switzerland, 12 April 2006.
Schweizer Archiv fur Tierheilkunde    June 17, 2006   Volume 148, Issue 4 199-213 doi: 10.1024/0036-7281.148.4.199
No abstract available
Signaling through the small G-protein Cdc42 is involved in insulin-like growth factor-I resistance in aging articular chondrocytes.
Journal of orthopaedic research : official publication of the Orthopaedic Research Society    June 17, 2006   Volume 24, Issue 8 1765-1772 doi: 10.1002/jor.20185
Fortier LA, Miller BJ.During aging, chondrocytes become unresponsive to insulin-like growth factor-I (IGF-I). This study examined the role of Cdc42 (cell-division-cycle 42) in IGF-I signaling during aging. Experiments were performed using cartilage and chondrocytes isolated from horses ages 1 day-25 years. Northern analysis was used to examine expression of the small GTPases Cdc42, Rac, and RhoA. Western analysis was utilized to assess total Cdc42 (GTP + GDP-bound); active, GTP-Cdc42 was assessed using a pulldown assay with Western analysis. GTP-Cdc42 was also measured following IGF-I treatment. Gene expression for...