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Topic:Horse Racing

Horse racing is a competitive equestrian sport involving horses ridden by jockeys over set distances, often on flat tracks or over obstacles. It is characterized by a variety of race types, including thoroughbred, harness, and steeplechase, each with distinct rules and traditions. The sport emphasizes speed, stamina, and strategy, with races typically categorized by distance, surface type, and horse age or breed. Horse racing plays a significant role in the equine industry, influencing breeding, training, and veterinary care practices. This page compiles peer-reviewed research studies and scholarly articles that explore the physiological demands, training methodologies, and health considerations associated with horse racing.
Race performance following epiglottic entrapment surgery in Thoroughbred yearlings.
Equine veterinary journal    May 10, 2019   Volume 52, Issue 1 52-58 doi: 10.1111/evj.13122
Curtiss AL, Aceto H, Embertson RM.Epiglottic entrapment can occur in yearling Thoroughbreds (TB); however, race performance following surgical correction is unknown. Objective: To determine the race performance of horses treated surgically for epiglottic entrapment as yearlings as compared to an untreated cohort. A second objective was to identify risk factors for treated horses not racing post-operatively. Methods: Retrospective cohort and case-control studies. Methods: Medical (1989-2014) and race records of 66 treated TB racehorses were reviewed. Observed abnormalities on pre- and post-operative endoscopic images and surgic...
Exercise-induced Pulmonary Hemorrhage: Is It Important and Can It Be Prevented?
The Veterinary clinics of North America. Equine practice    May 10, 2019   Volume 35, Issue 2 339-350 doi: 10.1016/j.cveq.2019.03.007
Crispe EJ, Lester GD.Exercise-induced pulmonary hemorrhage (EIPH) occurs commonly in horses undergoing strenuous exercise. Reported risk factors include racing in cold temperatures and wearing of bar shoes. In horses with documented moderate to severe EIPH, increasing the interval between races and adopting a negative race pace strategy may reduce the severity of EIPH in subsequent races. EIPH seems to have an impact on performance only when moderate to severe. This occurs in a small number of starters, approximately 6%. EIPH often is erratic in severity from race to race, although across a population it is weakly...
Epiglottopexy for the treatment of epiglottic retroversion in 2 horses.
Veterinary surgery : VS    May 7, 2019   Volume 48, Issue 5 820-824 doi: 10.1111/vsu.13232
Curtiss AL, Parente EJ.To report an epiglottopexy technique for the treatment of epiglottic retroversion (ER) in 2 horses. Methods: Case report. Methods: A 2-year-old thoroughbred gelding and a 6-year-old standardbred gelding, both with ER. Methods: Epiglottic retroversion was diagnosed via exercising endoscopic examination in both horses. Epiglottopexy technique was performed in both cases. Results: Both horses returned to previous racing class within 1 year after surgery. Repeat exercising endoscopy of 1 horse 6 months postoperatively revealed resolution of the ER. Conclusions: Epiglottopexy should be consider...
Evaluation of Biological Indicators of Fatigue and Muscle Damage in Arabian Horses After Race.
Journal of equine veterinary science    April 25, 2019   Volume 78 74-78 doi: 10.1016/j.jevs.2019.04.007
Mami S, Khaje G, Shahriari A, Gooraninejad S.The aim of this study was to assay changes in blood biochemical parameters that resulted from exercise-induced muscle fatigue in horses participating in the two races (1,250 and 1,400 meters). Six male Arabian horses (3 to 6 years old) were used in this study. Blood samples were collected at time intervals including 1 hour before the race, immediately after the race, 1 and 24 hours after the end of race. Catalase (CAT), superoxide dismutase, glutathione peroxidase (GPX) activities, the blood level of malondialdehyde, protein carbonyl, and total antioxidant capacity (TAC) were measured, as w...
Alar fold resection in 25 horses: Clinical findings and effect on racing performance and airway mechanics (1998-2013).
Veterinary surgery : VS    April 19, 2019   Volume 48, Issue 5 835-844 doi: 10.1111/vsu.13214
Strand E, Össurardóttir S, Wettre KB, Fjordbakk CT.To report clinical findings and performance in horses in which alar fold collapse (AFC) had been diagnosed and surgically treated and to assess form and degree of respiratory obstruction. Methods: Retrospective case series. Methods: Twenty-one standardbreds, 2 coldblooded trotter racehorses, 1 thoroughbred, and 1 Icelandic horse. Methods: Alar fold collapse was diagnosed on the basis of continuous abnormal expiratory flutter noise coinciding with filling of the false nostrils during exercise on a high-speed treadmill that was alleviated by suturing the alar folds (AF) temporarily in a dorsal p...
The prevalence of elevated gamma-glutamyltransferase and sorbitol dehydrogenase activity in racing Thoroughbreds and their associations with viral infection.
Equine veterinary journal    April 10, 2019   Volume 51, Issue 6 738-742 doi: 10.1111/evj.13092
Ramsay JD, Evanoff R, Mealey RH, Simpson EL.In racehorses, serum gamma-glutamyltransferase (GGT) activity is positively correlated with cumulative days in training and, when ≥100 IU/L, has been associated with poor performance. The prevalence of increased GGT activity in North American Thoroughbreds and its aetiopathogenesis are unknown. Four emerging viruses, pegivirus E (PgV E; equine pegivirus), hepacivirus A (HcV A; equine hepacivirus), pegivirus D (PgV D; Theiler's disease virus), and equine parvovirus-hepatitis (EqPV-H) have been identified in horses with clinical and subclinical hepatopathy. Available prevalence data indicate ...
External mechanical work in the galloping racehorse.
Biology letters    April 9, 2019   Volume 15, Issue 2 20180709 doi: 10.1098/rsbl.2018.0709
Self Davies ZT, Spence AJ, Wilson AM.Horse locomotion is remarkably economical. Here, we measure external mechanical work of the galloping horse and relate it to published measurements of metabolic cost. Seven Thoroughbred horses were galloped (ridden) over force plates, under a racing surface. Twenty-six full strides of force data were recorded and used to calculate the external mechanical work of galloping. The mean sum of decrements of mechanical energy was -876 J (±280 J) per stride and increments were 2163 J (±538 J) per stride as horses were accelerating. Combination with published values for internal work and metabolic c...
A Thoroughbred racehorse with a unicortical palmar lateral condylar fracture returned to training 14 days after surgery: a hypothesis on the role of a single bone screw on crack propagation.
Journal of equine science    April 3, 2019   Volume 30, Issue 1 7-12 doi: 10.1294/jes.30.7
Brown HR, Peloso JG, Werner WC, Mecholsky JJ, Cohen ND, Vogler JB.A 2-year-old Thoroughbred racehorse had LF lameness that began post high-speed exercise and persisted for two days before the horse once again became sound. Diagnostic analgesia localized the lameness to the LF distal metacarpus, and a standing MRI identified a unicortical condylar fracture. A single 5.5 mm cortical screw was placed in lag fashion. The horse began hand walking at 14 days, racetrack jogging at 30 days, and racing at 5 months after the day of surgery. Placement of a single lag screw ahead of the tip of the crack in unicortical condylar fracture may be useful for reducing the rec...
Prevalence, radiographic resolution and outcomes of slab fractures of the third and central tarsal bones in juvenile Thoroughbred horses.
Australian veterinary journal    March 29, 2019   Volume 97, Issue 4 108-115 doi: 10.1111/avj.12790
Steel CM, Collins VL, Hance SR, Adkins AR, Hitchens PL.Veterinarians are required to interpret the significance of radiographic findings for sale, soundness and future racing performance of weanling and yearling Thoroughbreds. We investigated the prevalence and radiographic appearance of slab fractures of the third (T3) and central tarsal (Tc) bones. Methods: Weanling and yearling horses with complete or incomplete T3 or Tc fracture were identified by searching a database of radiographs. The prevalence and radiographic appearance at initial diagnosis and after continued pasture turnout, as well as prognosis for racing, of fractures of T3 and Tc we...
Distribution of Pelvic Fractures in Racing and Non-racing Sport Horses: A Retrospective Study of 86 Cases Examined in a Referral Centre.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    March 28, 2019   Volume 32, Issue 3 215-221 doi: 10.1055/s-0039-1683403
Moiroud CH, Coudry V, Denoix JM. The aim of this study was to analyse the pelvic fracture distribution and location in a referral centre caseload. Methods:  Medical records of 6,717 horses examined in a referral centre over a 7-year period were reviewed to identify all horses diagnosed with a pelvic fracture. Eighty-six horses were identified and divided into three disciplines, namely Thoroughbred racehorses (TBR), Standardbred trotter racehorses (STR) and non-racing sport horses (NRSH). Results:  A pelvic fracture was diagnosed in 1.3% of the cases examined during the study period. Prevalence was significantly higher ...
Cardiac Pathology and Genomics of Sudden Death in Racehorses From New York and Maryland Racetracks.
Veterinary pathology    March 27, 2019   Volume 56, Issue 4 576-585 doi: 10.1177/0300985819829529
Molesan A, Wang M, Sun Q, Pierce V, Desideri R, Palmer S, Todhunter R, Kelly K.Postmortem evaluation of racehorses has focused primarily on musculoskeletal injuries; however, horses also die suddenly on the track (sudden death [SD]). Although cardiac conditions are frequently suspected as a cause of death, SD racehorses are often autopsy negative; however, previous studies have been limited due to inconsistent or insufficient cardiac sampling and lack of controls. SD in New York (NY) and Maryland (MD) racehorses was evaluated in an observational case vs control study comparing clinical information, postmortem evaluation including cardiac dissection, and cardiac conductio...
Standing magnetic resonance imaging of distal phalanx fractures in 6 cases of Thoroughbred racehorse.
The Journal of veterinary medical science    March 21, 2019   Volume 81, Issue 5 689-693 doi: 10.1292/jvms.18-0183
Mizobe F, Nomura M, Kanai K, Ishikawa Y, Yamada K.Six Thoroughbred racehorses with palmar process fractures of the distal phalanx were evaluated with standing magnetic resonance imaging (sMRI). In all the cases, the fractures were detectable on T1-weighted images and fat-suppressed images. Furthermore, multi-planar reconstruction images were useful for assessing the articular involvement of the fractures. Follow-up sMRI was obtainable in 3 cases, which revealed that the area of high signal intensity on fat-suppressed images decreased over time as symptoms improved. Our findings support the use of sMRI for the detailed evaluation of distal pha...
Jockey injuries during the Siena “Palio”. A 72-year analysis of the oldest horse race in Italy.
Injury    March 19, 2019   Volume 50 Suppl 4 S56-S59 doi: 10.1016/j.injury.2019.03.015
Fortina M, Maniscalco P, Carulli C, Meccariello L, Colasanti GB, Carta S.Horse racing is a hazardous sport. We analyzed the incidence and characteristics of jockey injuries in a typical horse race. Methods: We analyzed all injuries sustained by 224 jockeys in the last 72 years. Results: It was found that in 96.1% of the races there was at least one fall and in 28.6% of the races 50% or more of the jockeys fell. In 43.4% of the falls, the jockey was taken to the emergency room. Comparing the Palio with traditional races in other countries, a higher injury incidence rate was observed for every 100 falls (109.884 vs 27-59) and a lower concussion rate/100 falls (0.97 v...
Solar angle of the distal phalanx is associated with scintigraphic evidence of subchondral bone injury in the palmar/plantar aspect of the third metacarpal/tarsal condyles in Thoroughbred racehorses.
Equine veterinary journal    March 19, 2019   Volume 51, Issue 6 720-726 doi: 10.1111/evj.13086
Walmsley EA, Jackson M, Wells-Smith L, Whitton RC.Subchondral bone injury at the palmar/plantar aspect of the condyles of the third metacarpal/metatarsal bone (MC/MT3) commonly causes lameness and poor performance in racehorses. Injury occurs due to repetitive loading, the magnitude of which may be influenced by the position of the distal phalanx relative to the ground surface, i.e. the solar angle. The association of solar angle and injury at the palmar/plantar condyles of distal MC/MT3 therefore warrants investigation. Objective: Investigate the relationship between solar angle and radiopharmaceutical uptake at the palmar/plantar aspect of ...
Pharmacokinetics, metabolism and excretion of celecoxib, a selective cyclooxygenase-2 inhibitor, in horses.
Journal of veterinary pharmacology and therapeutics    March 19, 2019   Volume 42, Issue 5 518-524 doi: 10.1111/jvp.12757
Subhahar MB, Singh J, Albert PH, Kadry AM.Celecoxib, a nonsteroidal anti-inflammatory drug, is frequently used to treat arthritis in humans with minimal gastrointestinal side effect compared to traditional NSAIDs. The primary aim of this study was to determine the pharmacokinetic profile of celecoxib-a selective cyclooxygenase-2 (COX-2) inhibitor in horses. Six horses were administered a single oral dose of celecoxib at 2 mg/kg (body weight). After oral dosing, the drug reached a maximum concentration (mean ± SD) in blood of 1,088 ± 324 ng/ml in 4.58 hr. The elimination half-life was 13.60 ± 3.18 hr, and the area under th...
Return to racing after surgical management of third carpal bone slab fractures in thoroughbred and standardbred racehorses.
Veterinary surgery : VS    March 18, 2019   Volume 48, Issue 4 513-523 doi: 10.1111/vsu.13193
Doering AK, Reesink HL, Luedke LK, Moore C, Nixon AJ, Fortier LA, Ducharme NG, Ross MW, Levine DG, Richardson DW, Stefanovski D, Ortved KF.To determine the prognosis for racing of horses surgically treated for slab fractures of the third carpal bone (C3). Methods: Retrospective case study. Methods: Horses (n = 125) surgically treated for C3 slab fractures. Methods: Medical records of horses surgically treated for dorsal or sagittal C3 fractures were reviewed for age, sex, breed, limb, fracture type, degree of cartilage damage, and surgical treatment. Radiographs were evaluated to determine fracture depth, width, and displacement. Osteophytes, C3 lysis, and fragmentation were scored. Racing performance was obtained from online...
Ultrasonic debridement with stem cell therapy of suspensory branch desmitis in an equine patient.
Open veterinary journal    March 12, 2019   Volume 9, Issue 1 54-57 doi: 10.4314/ovj.v9i1.10
Kamineni S, Ruggles A, Ashfaq H.Ultrasonic debridement as a treatment for tendinopathy and desmitis is a relatively new approach in orthopedic surgery. Previously only used in limited cases, this procedure shows promise for treating ligament-bone and tendon-bone interface injuries. We present a case study of a 2-yr-old thoroughbred male horse, unable to train due to recalcitrant symptoms after extensive conservative management of suspensory branch desmitis. It was then treated with ultrasonic debridement and concurrent manubrial stem cell autograft injection, to treat the ultrasound visualized lesion. Post-surgically, the pa...
Associations between pre-injury racing history and tibial and humeral fractures in Australian Thoroughbred racehorses.
Veterinary journal (London, England : 1997)    March 5, 2019   Volume 247 44-49 doi: 10.1016/j.tvjl.2019.03.001
Whitton RC, Walmsley EA, Wong ASM, Shannon SM, Frazer EJ, Williams NJ, Guerow JF, Hitchens PL.Long bone fractures in racehorses may present as stress fractures which have a good prognosis, or complete fractures, which often result in a fatal outcome. In order to identify differences in modifiable management practices that may contribute to these outcomes, racing histories of horses with humeral or tibial fractures and of matched controls were examined. A retrospective case-control study of Australian Thoroughbred racehorses diagnosed with a fracture of the humerus or tibia by scintigraphy or at post-mortem between 2002 and 2016 was undertaken. Control horses were matched from the same ...
Survey of trainers on the use of swimming exercise for Standardbred racehorses in Australia.
Australian veterinary journal    February 28, 2019   Volume 97, Issue 3 61-67 doi: 10.1111/avj.12786
Steel CM, Bond BM, Morrice-West AV.To determine swimming training practices in Australian harness racing horses and potential targets for future research. Methods: An online survey of Australian Standardbred trainers and telephone interviews with 20 leading trainers were conducted. Questions relating to swimming facility and protocol, perceived benefits and contraindications were included. Descriptive data analysis was performed. Results: Data were collected from 270 trainers: 250 by online survey (250/1770, response rate 14.1%) and 20 by interview. Of these, 103 trainers (38.1%), including 91 surveyed trainers (91/250, 36.4%) ...
Catastrophic musculoskeletal injuries in Thoroughbred racehorses on racetracks in Gauteng, South Africa.
Journal of the South African Veterinary Association    February 28, 2019   Volume 90 e1-e5 doi: 10.4102/jsava.v90i0.1640
Spargo KE, Rubio-Martinez LM, Wheeler DP, Fletcher L, Carstens A.The incidence and types of catastrophic musculoskeletal injuries in Thoroughbreds that resulted in euthanasia on selected racetracks in South Africa between 1998 and 2012 were investigated by an observational retrospective investigation. Data from the National Horseracing Authority of Southern Africa for these racetracks were used to calculate incidence rates in Thoroughbreds (n = 114) that sustained catastrophic musculoskeletal injuries during racing that required immediate euthanasia, based on the diagnosis made by the on-site veterinarian as well as on fetlock radiographs and dissections o...
Use of a 2.5% Cross-Linked Polyacrylamide Hydrogel in the Management of Joint Lameness in a Population of Flat Racing Thoroughbreds: A Pilot Study.
Journal of equine veterinary science    February 27, 2019   Volume 77 57-62 doi: 10.1016/j.jevs.2019.02.012
de Clifford LT, Lowe JN, McKellar CD, Bolwell C, David F.Osteoarthritis is one of the most common disease processes effecting equine athletes, causing up to 60% of all lameness. This prospective longitudinal study reports on the effect of treatment of carpal and metacarpophalangeal joint lameness with 2.5% cross-linked polyacrylamide hydrogel (PAAG). A total of 49 flat-racing Thoroughbreds at a single training facility were included in the study. The results show a significant improvement in lameness grades at weeks 1 (P < .01), 4 (P < .001), 12 (P < .001), and 24 (P < .001) when compared to baseline lameness at week 0. This pilot study ...
Revisiting predictive biomarkers of musculoskeletal injury in thoroughbred racehorses: longitudinal study in polish population.
BMC veterinary research    February 26, 2019   Volume 15, Issue 1 66 doi: 10.1186/s12917-019-1799-7
Turlo AJ, Cywinska A, Frisbie DD.High prevalence of musculoskeletal disorders in racehorses and its impact on horse welfare and racing economics call for improved measures of injury diagnosis and prevention. Serum biomarkers of bone and cartilage metabolism have previously shown promise in prediction of musculoskeletal injuries in horses. This study aimed to re-evaluate usability of the predictive serum biomarkers identified in North American Thoroughbred racehorses in a geographically distinct group of Polish Thoroughbreds. Results: Serum concentrations of bone and cartilage biomarkers: osteocalcin, c-terminal telopeptide of...
Heritability estimates of fractures in Japanese Thoroughbred racehorses using a non-linear model.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    February 21, 2019   Volume 136, Issue 3 199-204 doi: 10.1111/jbg.12387
Tozaki T, Miyake T, Kikuchi M, Kakoi H, Hirota KI, Kusano K, Ishikawa Y, Nomura M, Kushiro A, Nagata SI.Thoroughbred racehorses are produced by mating small numbers of Arabian stallions and native British mares, and have been improved by selection of horseracing performance for about 300 years. While these improvements led to good performance as racehorses, they exposed horses to numerous medical disorders, aggravated by extensive exercise. Fractures are frequent medical disorders in Thoroughbred racehorses. In this study, fracture heritability was estimated using 3,927 Japanese Thoroughbred racehorses to elucidate the risk of racehorse fractures. The heritability estimates of all examined frac...
Fragmentation of the dorsal distal aspect of the talus on weanling survey and pre-sale radiographs of juvenile Thoroughbreds: prevalence and 2- and 3-year-olds racing performance.
Australian veterinary journal    February 17, 2019   Volume 97, Issue 3 68-74 doi: 10.1111/avj.12787
Steel CM, Devery S, Hance SR, Adkins AR, Hitchens PL.Fragmentation of the dorsal aspect of the distal talus (FDDT), at the dorsolateral articular margin of the proximal intertarsal joint (PITJ) on pre-sale radiographs of yearling Thoroughbreds has not been previously described and data to support decisions made by veterinarians to predict future racing potential of horses with these lesions are lacking. Methods: In this retrospective case-control study we aimed to determine the prevalence of FDDT in juvenile Thoroughbreds and to report their race records. From a database of survey and repository radiographic examinations of 5709 horses, 36 with ...
Assessment of two methods to determine the relative contributions of the aerobic and anaerobic energy systems in racehorses.
Journal of applied physiology (Bethesda, Md. : 1985)    February 14, 2019   Volume 126, Issue 5 1390-1398 doi: 10.1152/japplphysiol.00983.2018
Bond SL, Greco-Otto P, Sides R, Kwong GPS, Léguillette R, Bayly WM.A prospective, randomized, controlled study was designed to determine relative aerobic and anaerobic (lactic and alactic) contributions at supramaximal exercise intensities using two different methods. Thoroughbred racehorses ( = 5) performed a maximal rate of oxygen consumption (V̇o) test and three supramaximal treadmill runs (105, 115, and 125% V̇o). Blood lactate concentration (BL) was measured at rest, every 15 s during runs, and 2, 5, 10, 20, 30, 40, 50, and 60 min postexercise. In , oxygen demand was calculated for each supramaximal intensity based on the V̇o test, and relative aerobi...
The lipidome of Thoroughbred racehorses before and after supramaximal exercise.
Equine veterinary journal    February 9, 2019   Volume 51, Issue 5 696-700 doi: 10.1111/evj.13064
Nolazco Sassot L, Villarino NF, Dasgupta N, Morrison JJ, Bayly WM, Gang D, Sanz MG.A comprehensive study of the effect of supramaximal exercise in lipid homeostasis of Thoroughbreds provides the basis for future research on the role of lipids on energy metabolism in racehorses. Objective: To compare the plasma lipidome of Thoroughbreds before and after supramaximal exercise using an untargeted lipidomics approach. Methods: Pilot experimental study. Methods: Four Thoroughbred horses were used. The maximal oxygen consumption (VO ) was calculated for each horse. Horses then underwent treadmill exercise at the speed for which the oxygen requirements had been calculated to be 11...
A retrospective cohort study of racing performance in Quarter Horses undergoing prosthetic laryngoplasty for treatment of recurrent laryngeal neuropathy.
Journal of the American Veterinary Medical Association    February 5, 2019   Volume 254, Issue 4 496-500 doi: 10.2460/javma.254.4.496
Krueger CR, Lewis RD, McIlwraith CW, Major MD, Brakenhoff JE, Hand DR, Rowland AL, Hess AM, Johnson SW, Hackett ES.OBJECTIVE To determine effects of prosthetic laryngoplasty on return to racing, performance index, and career longevity in racing Quarter Horses with recurrent laryngeal neuropathy (RLN) and to evaluate performance variables for horses with RLN undergoing prosthetic laryngoplasty, compared with a control horse population. DESIGN Multicenter, retrospective cohort study. ANIMALS 162 racing Quarter Horses with RLN treated with prosthetic laryngoplasty (case horses) and 324 racing Quarter Horse without RLN (control horses). PROCEDURES Medical and race records of case and control horses examined at...
Comparison of the racing performance of Thoroughbreds with versus without osteochondral fragmentation of the accessory carpal bone identified on yearling sales repository radiographs.
Journal of the American Veterinary Medical Association    February 5, 2019   Volume 254, Issue 4 501-507 doi: 10.2460/javma.254.4.501
Davern AJ, Peloso JG, Hawkins JF, Moore GE, Morehead JP.OBJECTIVE To evaluate 2- and 3-year-old and career race performance of Thoroughbred racehorse prospects with and without osteochondral fragmentation of the accessory carpal bone (ACB) identified on yearling presale radiographs. DESIGN Retrospective, matched cohort study. ANIMALS 47 nonlame Thoroughbreds with (exposed cohort) and 94 nonlame Thoroughbreds without (unexposed cohort) osteochondral fragmentation of ACB facture identified on yearling sales repository radiographs. PROCEDURES Repository radiographic interpretation reports for September yearling sales of a large Kentucky auction house ...
Exploring the genetics of trotting racing ability in horses using a unique Nordic horse model.
BMC genomics    February 4, 2019   Volume 20, Issue 1 104 doi: 10.1186/s12864-019-5484-9
Velie BD, Lillie M, Fegraeus KJ, Rosengren MK, Solé M, Wiklund M, Ihler CF, Strand E, Lindgren G.Horses have been strongly selected for speed, strength, and endurance-exercise traits since the onset of domestication. As a result, highly specialized horse breeds have developed with many modern horse breeds often representing closed populations with high phenotypic and genetic uniformity. However, a great deal of variation still exists between breeds, making the horse particularly well suited for genetic studies of athleticism. To identify genomic regions associated with athleticism as it pertains to trotting racing ability in the horse, the current study applies a pooled sequence analysis ...
The Effect of Race Training on the Basal Gene Expression of Alveolar Macrophages Derived From Standardbred Racehorses.
Journal of equine veterinary science    January 29, 2019   Volume 75 48-54 doi: 10.1016/j.jevs.2019.01.010
Karagianni AE, Summers KM, Couroucé A, Depecker M, McGorum BC, Hume DA, Pirie RS.Mild-to-moderate equine asthma is prevalent in young racehorses, particularly early in their training period. Although the precise etiopathogenesis remains undetermined, it is possible that the susceptibility of this population might partly reflect an exercise-associated immune derangement at the level of the airway. We performed a genome-wide basal gene expression scan on alveolar macrophages (AMs) isolated from Standardbred racehorses before and after commencement of competition race training with a view to identifying any exercise-associated gene expression modulation consistent with functi...
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