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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Corneal thickness and anterior chamber depth of the normal adult horse as measured by ultrasound biomicroscopy.
Veterinary ophthalmology    January 27, 2022   Volume 25 Suppl 1, Issue Suppl 1 17-24 doi: 10.1111/vop.12971
Knickelbein KE, Lassaline ME, Kim S, Scharbrough MS, Thomasy SM.To determine corneal thickness (CT) and axial anterior chamber depth (ACD) using ultrasound biomicroscopy (UBM) in normal adult horses. To compare corneal thickness measurements between UBM and ultrasonic pachymetry. Methods: Sixty eyes of 30 healthy adult horses aged 8-24 years. Methods: Ultrasonic pachymetry (velocity of 1640 m/s) was utilized to obtain measurements of the central, superior, temporal, inferior, and nasal cornea. Triplicate images of the same corneal locations were acquired using UBM (50 MHz). Images of the axial anterior chamber were used to measure ACD. Intraocular pres...
The Gingiva of Horses With Pituitary Pars Intermedia Dysfunction: A Macroscopic Anatomical Evaluation.
Frontiers in veterinary science    January 25, 2022   Volume 8 786971 doi: 10.3389/fvets.2021.786971
Nitzsche AM, Fey K, Büttner K, Gröf M, Staszyk C.Pituitary pars intermedia dysfunction (PPID) is a common neurodegenerative disease mainly in horses older than 15 years. The domestic equine population is following the same demographic change as that seen in humans; it is aging and veterinarians are asked to attend to geriatric horses more frequently. Common problems seen regularly in older equines are dental disorders and especially periodontal disease. As a systemic and endocrine disease, associated with delayed wound healing and impaired immune function, PPID should be considered before major dental treatment in aged equines is started. Po...
Seroepidemiological Survey of West Nile Virus Infections in Horses from Berlin/Brandenburg and North Rhine-Westphalia, Germany.
Viruses    January 25, 2022   Volume 14, Issue 2 243 doi: 10.3390/v14020243
Bergmann F, Trachsel DS, Stoeckle SD, Bernis Sierra J, Lübke S, Groschup MH, Gehlen H, Ziegler U.Following the introduction of the West Nile virus (WNV) into eastern Germany in 2018, increasing infections have been diagnosed in birds, equines, and humans over time, while the spread of WNV into western Germany remained unclear. We screened 437 equine sera from 2018 to 2020, excluding vaccinated horses, collected from convenience sampled patients in the eastern and western parts of Germany, for WNV-specific antibodies (ELISAs followed by virus/specific neutralization tests) and genomes (RT-qPCRs). Clinical presentations, final diagnoses, and demographic data were also recorded. In the easte...
Development of a microsphere-based immunoassay for the serological diagnosis of equine trypanosomosis.
Scientific reports    January 25, 2022   Volume 12, Issue 1 1308 doi: 10.1038/s41598-022-05356-y
Verney M, Gautron M, Lemans C, Rincé A, Hans A, Hébert L.Trypanozoon infections in equids are caused by three parasite species in the Trypanozoon subgenus: Trypanosoma equiperdum, T. brucei and T. evansi. They are respectively responsible for infectious diseases dourine, nagana and surra. Due to the threat that Trypanozoon infection represents for international horse trading, accurate diagnostic tests are crucial. Current tests suffer from poor sensitivity and specificity, due in the first case to the transient presence of parasites in the blood and in the second, to antigenic cross-reactivity among Trypanozoon subspecies. This study was designed to...
First phalanx exostosis in traditional equestrian horses in Western Libya.
Open veterinary journal    January 25, 2022   Volume 12, Issue 1 69-74 doi: 10.5455/OVJ.2022.v12.i1.8
Abushhiwa MH, Elmeshreghi TN, Alrtib AM, Bennour EM, Oheida AH.Orthopedic diseases involving the forelimb fetlock joint of horses other than those used in professional racing have not been widely reported in the literature. One of these problems is the exostosis on the proximal forelimb phalanx (P1), which has not been reported previously in Western Libya. The study aimed to investigate the prevalence of P1 exostosis in traditional equestrian horses (known locally as Sarj horses) of different breeds in Libya that participated in a special social event and described its clinical findings radiographic appearance. The current study involved 60 horses admitte...
Identification of processed pseudogenes in the genome of Thoroughbred horses: Possibility of gene-doping detection considering the presence of pseudogenes.
Animal genetics    January 25, 2022   Volume 53, Issue 2 183-192 doi: 10.1111/age.13174
Tozaki T, Ohnuma A, Kikuchi M, Ishige T, Kakoi H, Hirota KI, Kusano K, Nagata SI.Processed pseudogenes, also known as retrocopy genes, are copies of messenger RNAs that have been reverse transcribed into DNA and inserted into the genome. In this study, we identified 62 processed pseudogene candidates as intron-less genes from whole-genome sequencing (WGS) data of Thoroughbred horses using delly structural variation software. The 62 processed pseudogene candidates were confirmed by PCR amplification of intron-less products. A total of 11 processed pseudogenes were confirmed in the genome of all 23 analysed horses, whereas three processed pseudogenes with structures of ATP11...
Successive approximation of horses to their first work on a treadmill: The effect of previous loading into a trailer.
Animal science journal = Nihon chikusan Gakkaiho    January 25, 2022   Volume 93, Issue 1 e13687 doi: 10.1111/asj.13687
Maśko M, Lewczuk D, Szarska E, Domino M.A horse learning about the entrance to narrow, cage-shaped places may be challenging both for the horses as well as for the owners. For some behaviors, such as loading into a trailer or climbing onto a treadmill, the final behavioral goal can be achieved by working towards it in stages. This study compared the successive approximation of horses to their first work on a treadmill with horses hardly ever loaded (HE L) and regularly loaded (R L) into a trailer. Fourteen horses were divided into two groups (HE L n = 7 and R L n = 7) based on their experiences of entering into a trailer. Al...
Effects of BEMER® physical vascular therapy in horses under training. A randomized, controlled double blind study.
Research in veterinary science    January 24, 2022   Volume 144 108-114 doi: 10.1016/j.rvsc.2022.01.017
Dai F, Costa ED, Giordano A, Heinzl EUL, Giongo P, Pagnozzi G, Cannas S, Minozzi G, Minero M.Horses preparation for competition may cause psychological and physical stress. Physical vascular therapy BEMER® is reported to increase vasomotion and microcirculation, supporting body healing. This study aimed at assessing whether BEMER® physical vascular therapy in horses influences recovery rate of hematological and biochemical blood parameters within 1 h after moderate exercise and reduces stress measured by physiological and behavioral indicators. This prospective, randomized, double blinded, placebo-controlled crossover study included twelve warmblood horses (3 mares, 8 geldings, 1 s...
Effects of a Bio-Electromagnetic Energy Regulation Blanket on Thoracolumbar Epaxial Muscle Pain in Horses.
Journal of equine veterinary science    January 23, 2022   Volume 111 103867 doi: 10.1016/j.jevs.2022.103867
King MR, Seabaugh KA, Frisbie DD.Back pain and inflammation of the epaxial musculature is a significant problem in all equine athletes. Treatment of back pain can be challenging and often requires a multimodal approach. In humans, bio-electromagnetic energy regulation therapy (BEMER) has been reported to be effective in pain modulation. With its increased use in people comes a similar robust application in veterinary medicine unfortunately, there is unsubstantiated evidence for this type of therapy in horses. Objectives of this study were to assess analgesic responses and biomechanical outcome variables using a bio-electromag...
Osteochondral regeneration of the femoral medial condyle by using a scaffold-free 3D construct of synovial membrane-derived mesenchymal stem cells in horses.
BMC veterinary research    January 22, 2022   Volume 18, Issue 1 53 doi: 10.1186/s12917-021-03126-y
Murata D, Ishikawa S, Sunaga T, Saito Y, Sogawa T, Nakayama K, Hobo S, Hatazoe T.Medical interventions for subchondral bone cysts in horses have been extensively studied. This study investigated the regeneration of articular cartilage and subchondral bone with scaffold-free three-dimensional (3D) constructs of equine synovial membrane-derived mesenchymal stem cells (SM-MSCs) isolated from three ponies and expanded until over 1.0 × 10 cells at passage 2 (P2). Results: SM-MSCs were strongly positive for CD11a/CD18, CD44, and major histocompatibility complex (MHC) class I; moderately positive for CD90, CD105, and MHC class II; and negative for CD34 and CD45 on flow cytom...
Current Use of Equine Laparoscopy in Urogenital Disorders: A Scoping Review of the Literature from 2000 to 2021.
Veterinary sciences    January 22, 2022   Volume 9, Issue 2 41 doi: 10.3390/vetsci9020041
Straticò P, Guerri G, Palozzo A, Varasano V, Petrizzi L.(1) Background: Laparoscopic surgery replaced traditional invasive techniques for the treatment of common urogenital disorders in equids. The aim of this review is to evaluate applications and the development of urogenital laparoscopy from 2001 to 2021. (2) Methods: A scoping review of literature was undertaken according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines for scoping reviews on three databases (NCBI-PubMed, Web of Science-Thompson Reuters, and SciVerse Scopus). (3) Results: A total of 452 papers were identified. After duplicate removal...
The Effects of the EquiAmiTM Training Aid on the Kinematics of the Horse at the Walk and Trot In-Hand.
Journal of equine veterinary science    January 22, 2022   Volume 111 103868 doi: 10.1016/j.jevs.2022.103868
Calzone S, Wilkins C, Deckers I, Nankervis K.The EquiAmi Training Aid (ETA) is a popular training and rehabilitation tool, however knowledge about its effect on the equine gait is lacking. Understanding of its effects on equine kinematics, and the clinical relevance of these effects is vital to promote optimal use of training aids within training and rehabilitation programmes. Therefore, this study aimed to determine how the ETA influences horses' gait kinematics at walk and trot. Eight horses walked and trotted in-hand with and without the ETA. Optical motion capture was used to measure forelimb and hindlimb pro- and retraction angles, ...
Lethal foal syndrome affects thoroughbreds too.
The Veterinary record    January 22, 2022   Volume 190, Issue 2 62-63 doi: 10.1002/vetr.1402
Mills G.For the first time researchers have confirmed a case of fragile foal syndrome in a non-warmblood horse. Georgina Mills reports.
Use of the SpO2/FiO2 Diagram to Assess Gas Exchange in Horses Under General Anaesthesia.
Journal of equine veterinary science    January 21, 2022   Volume 111 103874 doi: 10.1016/j.jevs.2022.103874
Scardia A, Mariani Pimenta EL, Ross Russell RI, Jones GJ, Staffieri F.The aim of this study was to evaluate the validity of the SpO/FiO diagram in estimating gas exchange in horses under general anaesthesia. In this prospective, controlled clinical study were included 10 horses under general anaesthesia. FiO was progressively reduced with the following steps: 0.6, 0.4, 0.3 and 0.21; SpO was recorded at each step. An arterial blood sample was collected at the steps of 1.0 and 0.21, to calculate intrapulmonary shunt with the Fshunt formula. The Fshunt value calculated at 0.21 FiO was defined as "Fshunt 0.21", the one calculated at 1.0 FiO as "Fshunt 1.0". The FiO ...
Racing-associated fatalities in Norwegian and Swedish harness racehorses: Incidence rates, risk factors, and principal postmortem findings.
Journal of veterinary internal medicine    January 21, 2022   Volume 36, Issue 2 778-786 doi: 10.1111/jvim.16364
Hellings IR, Skjerve E, Karlstam E, Valheim M, Ihler CF, Fintl C.There are no reports on the number of fatalities or causes of death in the Norwegian and Swedish harness racehorses. Objective: The incidence rates (IRs), risk factors, and postmortem findings in horses that died or were euthanized associated with racing between 2014 and 2019 were investigated. Methods: Thirty-eight Standardbreds and 10 Norwegian-Swedish Coldblooded Trotters died or were euthanized associated with racing. A total of 816 085 race-starts were recorded. Methods: Incidence rates were calculated for both countries and horse breeds. Risk factors for sudden death were identified us...
Dynamic three-dimensional computed tomographic imaging facilitates evaluation of the equine cervical articular process joint in motion.
Equine veterinary journal    January 21, 2022   Volume 55, Issue 1 83-91 doi: 10.1111/evj.13560
Schulze N, Werpy N, Gernhardt J, Fritsch G, Hildebrandt T, Vanderperren K, Klopfleisch R, Ben Romdhane R, Lischer C, Ehrle A.Dynamic computed tomography (CT) imaging has been introduced in human orthopaedics and is continuing to gain popularity. With dynamic CT, video sequences of anatomical structures can be evaluated in motion. Objective: To investigate the feasibility of dynamic CT for diagnostic imaging of the equine cervical articular process joints (APJs) and to give a detailed description of the APJ movement pattern. Methods: Descriptive cadaver imaging. Methods: Cervical specimens of twelve Warmblood horses were included. A custom-made motorised testing device was used to position and manipulate the neck spe...
Equine Proliferative Enteropathy in Weanling Foals on A German Breeding Farm: Clinical Course, Treatment and Long-Term Outcome.
Journal of equine veterinary science    January 21, 2022   Volume 111 103873 doi: 10.1016/j.jevs.2022.103873
Dohrmann J, Hildebrand F, Straub J, Wadephul R, Pusterla N, Freise F, Venner M.The goal of the current report was to describe the clinical signs, therapy and outcome of foals with suspected equine proliferative enteropathy (EPE) due to an infection with Lawsonia intracellularis. Forty foals, born on the same breeding farm, were diagnosed with suspected clinical EPE between September 2019 and January 2020. Data of these cases were analyzed retrospectively regarding the course of the disease, treatment, outcome and long-term prognosis. All horses, including randomly selected control horses, were reassessed about nine months after the suspicion of EPE. The horses affected w...
Clostridioides difficile infection and One Health: an equine perspective.
Environmental microbiology    January 21, 2022   Volume 24, Issue 3 985-997 doi: 10.1111/1462-2920.15898
Hain-Saunders NMR, Knight DR, Bruce M, Riley TV.Clostridioides (Clostridium) difficile presents a significant health risk to humans and animals. The complexity of the bacterial-host interaction affecting pathogenesis and disease development creates an ongoing challenge for epidemiological studies, control strategies and prevention planning. The recent emergence of human disease caused by strains of C. difficile found in animals adds to mounting evidence that C. difficile infection (CDI) may be a zoonosis. In equine populations, C. difficile is a known cause of diarrhoea and gastrointestinal inflammation, with considerable mortality and morb...
Perinatal Stress in Immature Foals May Lead to Subclinical Adrenocortical Dysregulation in Adult Horses: Pilot Study.
Journal of equine veterinary science    January 21, 2022   Volume 111 103869 doi: 10.1016/j.jevs.2022.103869
Clothier J, Small A, Hinch G, Brown WY.The persistent endocrinological effects of perinatal stress due to gestational immaturity in horses are unknown, although effects have been reported in other livestock species. This pilot study tested the hypothesis that persistent adrenocortical dysregulation is present in horses that were gestationally immature at birth by assessing the salivary cortisol response to exogenous ACTH. Case horses (n = 10) were recruited with histories of gestation length < 315 d or dysmaturity observable through neonatal signs. Positive controls (n = 7) and negative controls (n = 5) were recruited wher...
Effects of age, disease and anastomosis on short- and long-term survival after surgical correction of small intestinal strangulating diseases in 89 horses.
Equine veterinary journal    January 21, 2022   Volume 54, Issue 6 1031-1038 doi: 10.1111/evj.13558
Rudnick MJ, Denagamage TN, Freeman DE.Although survival rates have been reported after small intestinal surgery for strangulating diseases in horses, none have followed survival for periods relevant to the long lifespan of horses and none have described effect of age, disease and surgical treatments over such long survival periods. Objective: To examine effects of age, disease and type of surgery on long-term survival in horses after surgical treatment of small intestinal strangulating diseases over periods relevant to the expected lifespan of a horse. Methods: Retrospective clinical study. Methods: Post-operative data were gather...
National genomic evaluation of Korean thoroughbreds through indirect racing phenotype.
Animal bioscience    January 21, 2022   Volume 35, Issue 5 659-669 doi: 10.5713/ab.21.0409
Lee J, Shin D, Kim H.Thoroughbred horses have been bred exclusively for racing in England for a long time. Additionally, because horse racing is a global sport, a healthy leisure activity for ordinary citizens, and a high-value business, systematic racehorse breeding at the population level is a requirement for continuous industrial development. Therefore, we established genomic evaluation system (using prize money as horse racing traits) to produce spirited, agile, and strong racing horse population. Methods: We used phenotypic data from 25,061 Thoroughbred horses (all registered individuals in Korea) that compet...
Echocardiographic Findings of a Donkey (Equus asinus) Jenny with Suspected Mitral Valve Dysplasia.
Journal of equine veterinary science    January 21, 2022   Volume 111 103871 doi: 10.1016/j.jevs.2022.103871
Xue C, Cavanaugh SM.Reports of ante-mortem diagnosis of cardiovascular diseases in donkeys (Equus asinus) are rare. This case report describes the echocardiographic findings of suspected mitral valve dysplasia in a 3-year-old Nevisian donkey jenny presented for evaluation of a grade III/VI left-sided systolic murmur. Pertinent findings on transthoracic echocardiography included double mitral regurgitant jets and a bridge of tissue between the septal and mural mitral leaflets. Based upon the mild degree of cardiac remodeling and absence of clinical signs, therapeutic intervention was deemed unnecessary, and the je...
Effect of intrabronchial administration of autologous adipose-derived mesenchymal stem cells on severe equine asthma.
Stem cell research & therapy    January 21, 2022   Volume 13, Issue 1 23 doi: 10.1186/s13287-022-02704-7
Adamič N, Prpar Mihevc S, Blagus R, Kramarič P, Krapež U, Majdič G, Viel L, Hoffman AM, Bienzle D, Vengust M.Severe equine asthma (SEA) is a common chronic respiratory disease and a significant health and well-being problem in horses. Current therapeutic strategies improve pulmonary function and clinical signs in some horses, but in the long-term, return to full athletic function appears to be rare. The aim of this study was to assess the safety and the effect of intrabronchial administration of adipose-derived mesenchymal stem cells (AD-MSC) on pulmonary inflammatory and clinical parameters in horses with SEA. This was a randomized controlled trial. Twenty adult horses diagnosed with SEA were random...
Caecal microbiota in horses with trigeminal-mediated headshaking.
Veterinary medicine and science    January 21, 2022   Volume 8, Issue 3 1049-1055 doi: 10.1002/vms3.735
Aleman M, Sheldon SA, Jospin G, Coil D, Stratton-Phelps M, Eisen J.Trigeminal-mediated headshaking (TMHS) in horses is a form of neuropathic pain of undetermined cause that often results in euthanasia. The role of microbiota in TMHS has not been investigated in diseased horses. To investigate if gastrointestinal microbiota in the cecum is different in horses with TMHS compared to a control population, during a summer season with clinical manifestations of disease. Ten castrated horses: five with TMHS and five neurologically normal controls. All horses were sourced from our institution and kept under the same husbandry and dietary conditions. All horses were f...
Evaluation of the Effects of Doxapram in Combination with Xylazine on Recovery of Horses Isoflurane-Anesthetized.
Journal of equine veterinary science    January 21, 2022   Volume 111 103872 doi: 10.1016/j.jevs.2022.103872
Midon M, Yamada DI, Zangirolami Filho D, Natalini CC, Escobar A, Clark-Price SC.This randomized double-blinded study evaluated the recovery from isoflurane anesthesia in horses receiving doxapram and xylazine. 6 horses were anesthetized 4 times (minimum of 2-week washout period). Anesthesia was performed with xylazine (0.6 mg/kg), ketamine (2.2 mg/kg), midazolam (0.1 mg/kg), and maintained with isoflurane for 90 minutes. At recovery, horses received one of the following randomized treatments: RX: xylazine (0.2 mg/kg), RXD1: xylazine (0.2 mg/kg) and doxapram (0.1 mg/kg), RXD2: xylazine (0.2 mg/kg) and doxapram (0.2 mg/kg), or RS: saline. Recoveries were rope-assisted and e...
Interpreting abdominal fluid in colic horses: Understanding and applying peritoneal fluid evidence.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    January 20, 2022   Volume 32, Issue S1 81-96 doi: 10.1111/vec.13117
Radcliffe RM, Liu SY, Cook VL, Hurcombe SDA, Divers TJ.Interpreting changes in peritoneal fluid helps clinicians manage colic and other diseases in horses. During abdominal problems in the horse, abdominal fluid characteristics such as color, turbidity, total nucleated and red blood cell counts, cytology, total protein, and l-lactate change in predictable ways, helping the clinician characterize the disease. Methods: Normal abdominal fluid in horses is odorless, clear to light yellow in color, and transparent. Peritoneal fluid becomes more turbid with increasing levels of protein, number of WBCs or RBCs, or with gross contamination following intes...
Abdominocentesis techniques in horses.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    January 20, 2022   Volume 32, Issue S1 72-80 doi: 10.1111/vec.13118
Radcliffe RM, Hill JA, Liu SY, Cook VL, Hurcombe SDA, Divers TJ.Abdominocentesis is commonly used to evaluate the abdominal cavity of the horse. This technique provides valuable diagnostic information as well as the means to monitor patients with abdominal diseases being managed medically and to determine their need for surgical management. Complications are uncommon and include trauma to the gastrointestinal tract or spleen, septic peritonitis, or abdominal wall infection. Methods: This review describes the indications, utility, patient preparation, and instructions for performing abdominocentesis as well as possible complications reported in horses. Step...
Histological tissue healing following high-power laser treatment in a model of suspensory ligament branch injury.
Equine veterinary journal    January 20, 2022   Volume 54, Issue 6 1114-1122 doi: 10.1111/evj.13556
Pluim M, Heier A, Plomp S, Boshuizen B, Gröne A, van Weeren R, Vanderperren K, Martens A, Dewulf J, Chantziaras I, Koene M, Luciani A, Oosterlinck M....High-power laser therapy gained popularity recently as a regenerative treatment for tendinitis and desmitis in the horse. However, studies evaluating the effects of laser therapy on tissue repair at the histological level in large mammals are lacking. Objective: To evaluate the effects of high-power laser therapy on suspensory desmitis healing, using a model of suspensory ligament branch injury. Methods: In vivo experiments. Methods: Standardised lesions were surgically induced in all four lateral suspensory branches of 12 healthy Warmblood horses. Laser therapy (class 4, 15W) was applied dail...
How to perform a percutaneous cecal or colonic trocarization in horses with severe abdominal tympany.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    January 20, 2022   Volume 32, Issue S1 57-62 doi: 10.1111/vec.13123
Schroeder EL, Gardner AK, Mudge MC.Cecal or colonic gas tympany of any cause may result in increased intraabdominal pressure, causing a significant decrease in venous return and cardiac output. Trocarization of the large colon or cecum in the event of large intestinal tympany may resolve gas distension and accompanying increased intraabdominal pressures sufficiently enough to promote resolution of a displaced large colon. Furthermore, trocarization of the medical colic may decrease morbidity and mortality associated with severe intraabdominal hypertension. Methods: This how-to description details the technique of transcutaneous...
Effect of early or late blood sampling on thyrotropin releasing hormone stimulation test results in horses.
Journal of veterinary internal medicine    January 20, 2022   Volume 36, Issue 2 770-777 doi: 10.1111/jvim.16362
Thane K, Uricchio C, Frank N.Diagnosis of pituitary pars intermedia dysfunction (PPID) using the thyrotropin-releasing hormone (TRH) stimulation test requires blood collection 10 minutes after TRH injection; it is unknown if small differences in timing affect test results. Objective: To determine whether early or late sampling results in a significant (≥10%) difference in plasma adrenocorticotropic hormone (ACTH) concentration compared to standard 10-minute sampling. Methods: Twenty-four healthy adult horses with unknown PPID status. Methods: In this prospective study, subjects underwent a single TRH stimulation test, ...