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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Study of antimicrobial resistance and physiological biomarkers with special reference to Salmonellosis in diarrheic foals in Punjab, Pakistan.
Acta tropica    August 4, 2017   Volume 176 144-149 doi: 10.1016/j.actatropica.2017.08.003
Haq I, Durrani AZ, Khan MS, Mushtaq MH, Ahmad I.Antimicrobial resistance results in selective colonization in animals. In the present study, 447 diarrheic foals (235 horse foals, 165 donkey foals and 47 mule foal) were selected from Lahore and Sahiwal districts of Punjab, Pakistan. Fresh fecal and blood samples from diarrheic foals were collected for isolation and confirmation of Salmonella Polymerase chain reaction. Results revealed that 50 (11.25%) foals (horse n=29, donkey n=12 and mule n=9) were positive. Fifty Salmonella enterica isolates belonging to 7 serovars S. Paratyphi B (15), S. Saintpaul (7), S. Newport (6), S. Typhimu-rium (11...
Spirulina platensis Improves Mitochondrial Function Impaired by Elevated Oxidative Stress in Adipose-Derived Mesenchymal Stromal Cells (ASCs) and Intestinal Epithelial Cells (IECs), and Enhances Insulin Sensitivity in Equine Metabolic Syndrome (EMS) Horses.
Marine drugs    August 3, 2017   Volume 15, Issue 8 237 doi: 10.3390/md15080237
Nawrocka D, Kornicka K, Śmieszek A, Marycz K.Equine Metabolic Syndrome (EMS) is a steadily growing life-threatening endocrine disorder linked to insulin resistance, oxidative stress, and systemic inflammation. Inflammatory microenvironment of adipose tissue constitutes the direct tissue milieu for various cell populations, including adipose-derived mesenchymal stromal cells (ASCs), widely considered as a potential therapeutic cell source in the course of the treatment of metabolic disorders. Moreover, elevated oxidative stress induces inflammation in intestinal epithelial cells (IECs)-the first-line cells exposed to dietary compounds. In...
Effect of arthroscopic lavage and repeated intra-articular administrations of antibiotic in adult horses and foals with septic arthritis.
Veterinary surgery : VS    August 3, 2017   Volume 46, Issue 7 1008-1016 doi: 10.1111/vsu.12696
Cousty M, David Stack J, Tricaud C, David F.To evaluate the effect of arthroscopic lavage and repeated intra-articular administration of antibiotic in adult horses and foals with septic arthritis. Methods: Retrospective clinical study. Methods: Adult horses and foals with septic arthritis (n = 62). Methods: Age, sex, cause of septic synovitis, joint involved, hospitalization time, and outcome were recorded. Arthroscopic lavage was performed at day 0 (D 0). Synovial fluid was collected every 48 hours prior to intra-articular administration of antibiotic, and until hospital discharge. Synovial nucleated cell count, total protein, and ...
Complete Genome Sequences of Getah Virus Strains Isolated from Horses in 2016 in Japan.
Genome announcements    August 3, 2017   Volume 5, Issue 31 e00750-17 doi: 10.1128/genomeA.00750-17
Nemoto M, Bannai H, Ochi A, Niwa H, Murakami S, Tsujimura K, Yamanaka T, Kokado H, Kondo T.Getah virus is mosquito-borne and causes disease in horses and pigs. We sequenced and analyzed the complete genomes of three strains isolated from horses in Ibaraki Prefecture, eastern Japan, in 2016. They were almost identical to the genomes of strains recently isolated from horses, pigs, and mosquitoes in Japan.
Mitochondrial DNA Evidence Supports the Hypothesis that Triodontophorus Species Belong to Cyathostominae.
Frontiers in microbiology    August 3, 2017   Volume 8 1444 doi: 10.3389/fmicb.2017.01444
Gao Y, Zhang Y, Yang X, Qiu JH, Duan H, Xu WW, Chang QC, Wang CR.Equine strongyles, the significant nematode pathogens of horses, are characterized by high quantities and species abundance, but classification of this group of parasitic nematodes is debated. Mitochondrial (mt) genome DNA data are often used to address classification controversies. Thus, the objectives of this study were to determine the complete mt genomes of three Cyathostominae nematode species (, and ) of horses and reconstruct the phylogenetic relationship of Strongylidae with other nematodes in Strongyloidea to test the hypothesis that spp. belong to Cyathostominae using the mt genomes...
Epidemiological survey on equine cheek tooth infundibular caries in the United Kingdom.
The Veterinary record    August 3, 2017   Volume 181, Issue 9 235 doi: 10.1136/vr.104319
Borkent D, Reardon R, Dixon PM.Infundibular caries (IC) is an important equine dental disorder that can cause premature wear, fractures and apical infection of affected maxillary cheek teeth. No accurate prevalence values for IC are available for UK horses. The feeding of high levels of concentrates is believed to increase its prevalence, but no objective information is available on such possible environmental risk factors. The aims of the study were to document the prevalence of IC in UK horses, assess its distribution and severity between infundibulae and teeth in affected horses and examine for potential risk factors for...
Spectroscopic Study of the Interaction between Horse Heart Myoglobin and Zirconium(IV)-Substituted Polyoxometalates as Artificial Proteases.
Chemphyschem : a European journal of chemical physics and physical chemistry    August 3, 2017   Volume 18, Issue 18 2451-2458 doi: 10.1002/cphc.201700680
Ly HGT, Parac-Vogt TN.A recent study [Angew. Chem. Int. Ed. 2015, 54, 7391-7394] has shown that horse heart myoglobin (HHM) is selectively hydrolyzed by a range of zirconium(IV)-substituted polyoxometalates (POMs) under mild conditions. In this study, the molecular interactions between the Zr-POM catalysts and HHM are investigated by using a range of complementary techniques, including circular dichroism (CD), UV/Vis spectroscopy, tryptophan fluorescence spectroscopy, and H and P NMR spectroscopy. A tryptophan fluorescence quenching study reveals that, among all examined Zr-POMs, the most reactive POM, 2:2 Zr -...
[Anthelmintic resistance in ruminants: development, diagnostics, and procedures].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    August 2, 2017   Volume 45, Issue 4 244-251 doi: 10.15653/TPG-170287
Knubben-Schweizer G, Pfister K.Anthelmintic resistance of gastrointestinal nematodes in small ruminants, but also in cattle and horses, is now found worldwide. The reason for increasing anthelmintic resistance is, in particular, the extensive use of all the anthelmintic agents available on the market. A non-targeted use leads to the selection of naturally occurring resistance genes within parasite populations. The most practical method for evaluating the efficacy of an anthelmintic is the fecal egg-count reduction test. To reduce the rate of anthelmintic resistance development, the available active substances must be applie...
The evaluation of GM6-based ELISA and ICT as diagnostic methods on a Mongolian farm with an outbreak of non-tsetse transmitted horse trypanosomosis.
Veterinary parasitology    August 2, 2017   Volume 244 123-128 doi: 10.1016/j.vetpar.2017.07.036
Davaasuren B, Amgalanbaatar T, Musinguzi SP, Suganuma K, Otgonsuren D, Mossaad E, Narantsatsral S, Battur B, Battsetseg B, Xuan X, Inoue N.Trypanosoma equiperdum, which is the etiological agent of dourine, spreads through sexual intercourse in equines. Dourine (T. equiperdum) has been reported in Mongolia, where it is considered an economically important disease of horses. T. evansi has also been reported in Mongolian domestic animals. The objective of this study was to evaluate the potential application of recombinant T. evansi GM6 (rTeGM6-4r)-based diagnostic methods on a farm with an outbreak of non-tsetse transmitted horse trypanosomosis. Ninety-seven percent homology was found between the amino acid sequences of T. equiperdu...
Cecal entrapment within the epiploic foramen in a mare.
The Canadian veterinary journal = La revue veterinaire canadienne    August 2, 2017   Volume 58, Issue 8 842-844 
Grzeskowiak RM, Barrett EJ, Rodgerson DH.An 11-year-old Thoroughbred mare with colic unresponsive to medical treatment underwent exploratory laparotomy. During surgery the cecum was found entrapped within the epiploic foramen from left to right. The entrapped cecum was reduced through the foramen by gentle traction. After reduction of the cecum, rupture of the portal vein was detected. Loss of a large amount of blood prompted euthanasia during surgery. Une jument Thoroughbred âgée de 11 ans atteinte de coliques ne répondant pas au traitement médical a subi une laparatomie exploratoire. Durant la chirurgie, le cæcum a été trou...
Response to acupuncture treatment in horses with chronic laminitis.
The Canadian veterinary journal = La revue veterinaire canadienne    August 2, 2017   Volume 58, Issue 8 823-827 
Faramarzi B, Lee D, May K, Dong F.There is a need for evidence-based scientific research to address the question of the effectiveness of acupuncture in improving clinical signs of laminitis in horses. The objective of this study was to compare lameness levels before and after 2 acupuncture treatments in horses with chronic laminitis. Twelve adult horses with chronic laminitis received 2 acupuncture treatments 1 week apart. The points were treated using dry needling, hemo-acupuncture, and aqua-acupuncture. Lameness level was objectively evaluated using an inertial sensor-based lameness evaluation system (Lameness Locator), as w...
Pathology in Practice. Aspiration pneumonia.
Journal of the American Veterinary Medical Association    August 2, 2017   Volume 251, Issue 4 409-411 doi: 10.2460/javma.251.4.409
Anderson S, Wobeser B, Duke-Novakovski T, Singh B.No abstract available
The influence of aluminium, steel and polyurethane shoeing systems and of the unshod hoof on the injury risk of a horse kick. An ex vivo experimental study.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    August 1, 2017   Volume 30, Issue 5 339-345 doi: 10.3415/VCOT-17-01-0003
Sprick M, Fürst A, Baschnagel F, Michel S, Piskoty G, Hartnack S, Jackson MA.To evaluate the damage inflicted by an unshod hoof and by the various horseshoe materials (steel, aluminium and polyurethane) on the long bones of horses after a simulated kick. Methods: Sixty-four equine radii and tibiae were evaluated using a drop impact test setup. An impactor with a steel, aluminium, polyurethane, or hoof horn head was dropped onto prepared bones. An impactor velocity of 8 m/s was initially used with all four materials and then testing was repeated with a velocity of 12 m/s with the polyurethane and hoof horn heads. The impact process was analysed using a high-speed camera...
Application of the Hands-On Donkey Tool for Assessing the Welfare of Working Equids at Tuliman, Mexico.
Journal of applied animal welfare science : JAAWS    August 1, 2017   Volume 21, Issue 1 93-100 doi: 10.1080/10888705.2017.1351365
Galindo F, de Aluja A, Cagigas R, Huerta LA, Tadich TA.Equids are still used for diverse chores in Mexico and are essential for the livelihoods of numerous families. Appropriate health and behavior are prerequisites for performing work without affecting welfare. This study aimed to assess the welfare of working equids in Tuliman, applying the hands-on donkey tool. This tool evaluates five dimensions (behavior, body condition score [BCS], wounds, lameness, and other health issues) and was applied to 438 working equids (horses, mules, and donkeys). The Kruskall-Wallis test was applied to investigate differences between species and sex. Donkeys were ...
Correlation of dickkopf-1 concentrations in plasma and synovial fluid to the severity of radiographic signs of equine osteoarthritis.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    August 1, 2017   Volume 30, Issue 5 311-317 doi: 10.3415/VCOT-16-11-0157
Mills JS, Kinsley MA, Peters DF, Weber PSD, Shearer TR, Pease AP.The purpose of this study was to determine whether there was a correlation between circulating and intra-synovial Dkk-1 and radiographic signs of equine osteoarthritis. Methods: Circulating and intra-synovial Dkk-1 levels were measured in clinical cases using a commercially available human Dkk-1 ELISA. Radiographs were performed of the joints from which fluid was collected and these were assessed and scored by a boarded radiologist for joint narrowing, subchondral bone sclerosis, subchondral bone lysis, and periarticular modelling. Comparisons were made between radiographic scores and the conc...
Comparison of flocked and rayon swabs for the molecular detection of selected equine viruses and bacteria from nasal secretions of healthy horses.
The Veterinary record    August 1, 2017   Volume 181, Issue 8 197 doi: 10.1136/vr.104285
Pusterla N, Barnum S, Kenelty K.No abstract available
Pharmacokinetics and pharmacodynamics of meldonium in exercised thoroughbred horses.
Drug testing and analysis    August 1, 2017   Volume 9, Issue 9 1392-1399 doi: 10.1002/dta.2214
Knych HK, Stanley SD, McKemie DS, Arthur RM, Bondesson U, Hedeland M, Thevis M, Kass PH.Although developed as a therapeutic medication, meldonium has found widespread use in human sports and was recently added to the World Anti-Doping Agency's list of prohibited substances. Its reported abuse potential in human sports has led to concern by regulatory authorities about the possible misuse of meldonium in equine athletics. The potential abuse in equine athletes along with the limited data available regarding the pharmacokinetics and pharmacodynamics of meldonium in horses necessitates further study. Eight exercised adult thoroughbred horses received a single oral dose of 3.5, 7.1, ...
Influence of the Respiratory Cycle on Caudal Vena Cava Diameter Measured by Sonography in Healthy Foals: A Pilot Study.
Journal of veterinary internal medicine    August 1, 2017   Volume 31, Issue 5 1556-1562 doi: 10.1111/jvim.14793
Tuplin MC, Romero AE, Boysen SR.Intravascular volume assessment in foals is challenging. In humans, intravascular volume status is estimated by the caudal vena cava (CVC) collapsibility index (CVC-CI) defined as (CVC diameter at maximum expiration [CVC ] - CVC diameter at minimal inspiration [CVC ])/CVC × 100%. Objective: To determine whether the CVC could be sonographically measured in healthy foals, determine differences in CVC and CVC , and calculate inter- and intrarater variability between 2 examiners. We hypothesized that the CVC could be measured sonographically at the subxiphoid view and that there would be a differ...
Are serum amyloid A or D-lactate useful to diagnose synovial contamination or sepsis in horses?
The Veterinary record    August 1, 2017   Volume 181, Issue 16 425 doi: 10.1136/vr.104386
Robinson CS, Singer ER, Piviani M, Rubio-Martinez LM.Synovial sepsis in horses is life threatening and accurate diagnosis allowing prompt treatment is warranted. This study assessed the diagnostic value of serum amyloid A (SAA) and D-lactate in blood and synovial fluid (SF) as diagnostic markers of synovial sepsis in horses and correlated them with total nucleated cell count (TNCC), percentage of neutrophils (%N) and total protein (TP) in SF. Blood and SF SAA and D-lactate concentrations were determined in a case-control observational study including 112 horses (38 with synovial contamination or sepsis (SCS), 66 with non-septic intra-synovial pa...
A monoclonal antibody for detection of intracellular and secreted interleukin-2 in horses.
Veterinary immunology and immunopathology    July 31, 2017   Volume 191 30-35 doi: 10.1016/j.vetimm.2017.07.011
Freer H, Hillegas JM, Wimer C, Baldwin C, LaBresh J, Wagner B.Interleukin-2 (IL-2) is a T cell growth factor and major modulator of T helper (Th) cell differentiation. Here, we have developed and characterized a monoclonal antibody to equine IL-2 (anti-IL-2 mAb, clone 158-1). The IL-2 mAb detected rIL-2 by ELISA, intracellular staining and flow cytometry analysis and Western blotting. The IL-2 mAb was also paired with a polyclonal IL-2 detection antibody in both ELISA and a fluorescent bead-based assay. When these two assays were compared using identical reagents there was an improved analytical sensitivity (46pg/ml) and wider linear quantification range...
Diagnosis of equine influenza.
The Veterinary record    July 30, 2017   Volume 181, Issue 5 113-114 doi: 10.1136/vr.j3459
Rash A.During the summer months, there will be increased movement and, therefore, increased mixing of the horse population, leading to a higher risk of disease transmission and subsequent clinical cases. It is important that both vets and owners remain vigilant for equine influenza infection. Here, Adam Rash, of the Animal Health Trust, discusses the diagnosis of this disease.
First case of multidrug-resistant Enterococcus faecalis isolated from herding horse in Xinjiang, Western China.
The Journal of infection    July 29, 2017   Volume 75, Issue 5 468-469 doi: 10.1016/j.jinf.2017.07.006
Qi Y, Gong Z, Wang M, Song J, Gao J, Gao J, Li H, Xiao C, Zhang L.No abstract available
Maxillary unicystic ameloblastoma in a 6-week-old filly evaluated with computed tomography.
Australian veterinary journal    July 28, 2017   Volume 95, Issue 8 299-303 doi: 10.1111/avj.12610
Smith HL, Rosenblatt AJ, Suen WW, Owen H, Ahern BJ.A 6-week-old Thoroughbred filly was presented for evaluation of an expansile mass overlying the right nasal passage and causing respiratory stertor. On skull radiographs, there was a loculated, soft tissue-opaque mass identified dorsal to the right upper premolars and effacing the right nasal cavity. Computed tomography (CT) revealed a locally extensive mass with relatively benign characteristics located centrally on the tooth root apices of the deciduous second premolar (506). The mass extended axially into the right nasal cavity, occluding the meatuses and causing displacement of the nasal s...
SURVEY OF ANAPLASMA PHAGOCYTOPHILUM ANTIBODIES IN CAPTIVE PRZEWALSKI’S HORSES (EQUUS FERUS PRZEWALSKII).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians    July 28, 2017   Volume 48, Issue 2 506-509 doi: 10.1638/2016-0248R.1
Sim RR, Padilla LR, Joyner PH, Anikis P, Aitken-Palmer C.Anaplasma phagocytophilum (formerly Ehrlichia equi ) is a tickborne pathogen of domestic horses and the causative agent of equine granulocytic anaplasmosis. After the occurrence of clinical anaplasmosis in a Przewalski's horse ( Equus ferus przewalskii) housed at the Smithsonian Conservation Biology Institute in 2008, opportunistic serosurveillance of the herd was initiated. From 2008 to 2014, 57 serum samples were collected from 27 individuals (10 males; 17 females). Using indirect immunofluorescent antibody assays for anti- Anaplasma phagocytophilum antibodies, it was determined that prevale...
Investigation of the Fim1 putative pilus locus of Streptococcus equi subspecies equi.
Microbiology (Reading, England)    July 28, 2017   Volume 163, Issue 8 1217-1228 doi: 10.1099/mic.0.000506
Steward KF, Robinson C, Maskell DJ, Nenci C, Waller AS.The Gram-positive bacterium subspecies () is the causative agent of strangles, among the most frequently diagnosed infectious diseases of horses worldwide. Genome analysis of strain 4047 (4047) identified a putative operon, Fim1, with similarity to the pilus loci of other Gram-positive bacteria. The Fim1 locus was present in all strains of and its close relative subspecies () that have been studied to date. In this study we provide evidence that the putative structural pilus proteins, SEQ_0936 and CNE, are produced on the cell surface during growth and infection. Although the proteins ...
CLINICAL DISEASE ASSOCIATED WITH ANAPLASMA PHAGOCYTOPHILUM INFECTION IN CAPTIVE PRZEWALSKI’S HORSES (EQUUS FERUS PRZEWALSKII).
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians    July 28, 2017   Volume 48, Issue 2 497-505 doi: 10.1638/2016-0247R.1
Sim RR, Joyner PH, Padilla LR, Anikis P, Aitken-Palmer C.Anaplasma phagocytophilum is a tick-borne pathogen of domestic horses and the causative agent of equine granulocytic anaplasmosis. This case series describes three confirmed cases of clinical anaplasmosis, and a fourth case of presumptive anaplasmosis in Przewalski's horses ( Equus ferus przewalskii) housed at the Smithsonian Conservation Biology Institute from 2008 to 2014. Clinical signs varied among individuals with affected horses exhibiting lethargy, weakness, pyrexia, hypophagia, reluctance to move, or ataxia. Anaplasmosis cases were confirmed with a combination of identification of neut...
Molecular Epidemiology of a novel re-assorted epidemic strain of equine influenza virus in Pakistan in 2015-16.
Virus research    July 27, 2017   Volume 240 56-63 doi: 10.1016/j.virusres.2017.07.022
Khan A, Mushtaq MH, Ahmad MUD, Nazir J, Farooqi SH, Khan A.A widespread epidemic of equine influenza (EI) occurred in nonvaccinated equine population across multiple districts in Khyber Pakhtunkhwa Province of Pakistan during 2015-2016. An epidemiological surveillance study was conducted from Oct 2015 to April 2016 to investigate the outbreak. EI virus strains were isolated in embryonated eggs from suspected equines swab samples and were subjected to genome sequencing using M13 tagged segment specific primers. Phylogenetic analyses of the nucleotide sequences were concluded using Geneious. Haemagglutinin (HA), Neuraminidase (NA), Matrix (M) and nucleo...
The consistency and influence of environmental and animal factors on exhaled breath condensate hydrogen peroxide, pH and leukotriene B4 in horses.
Veterinary journal (London, England : 1997)    July 27, 2017   Volume 226 46-50 doi: 10.1016/j.tvjl.2017.07.005
du Preez S, Raidal SL, Doran GS, Nielsen SG, Hughes KJ.This study was performed to determine the consistency of exhaled breath condensate (EBC) hydrogen peroxide (HO), pH and leukotriene B (LTB) measurements in asymptomatic horses and to define the influence of environmental and animal factors on these variables. Intra- and inter-day consistency for both HO and pH measurements were adequate, with intraclass correlation coefficients ≥0.8, whereas the consistency for LTB was poor. HO was influenced by ambient temperature (T), humidity, time of day and collection location (all P<0.01), while pH was influenced by respiratory rate during EBC colle...
Reproductive phenology of Creole horses in Ecuador in the absence of photoperiod variation: The effects of forage availability and flooding affecting body condition of mares.
Animal science journal = Nihon chikusan Gakkaiho    July 27, 2017   Volume 88, Issue 12 2063-2070 doi: 10.1111/asj.12818
Carranza J, Yoong WA, Mateos C, Caño Vergara B, Gómez CL, Macías V.Horse reproduction tends to be seasonal. The main adjusting factor in their original temperate ranges is photoperiod variation, although it is absent in equatorial areas where horses were introduced by European colonizers. Hence, dates of reproduction in these areas may be influenced by factors affecting mares' conditions and the success of foaling. Here we study reproductive timing in Creole horses in Ecuador reared in an extensive production system. We found that foaling peaked in August. Mares' conditions showed one peak in June-July, before the start of the breeding season, and another in ...
Corrigendum to “Macroautophagy and Selective Mitophagy Ameliorate Chondrogenic Differentiation Potential in Adipose Stem Cells of Equine Metabolic Syndrome: New Findings in the Field of Progenitor Cells Differentiation”.
Oxidative medicine and cellular longevity    July 27, 2017   Volume 2017 3861790 doi: 10.1155/2017/3861790
Marycz K, Kornicka K, Grzesiak J, Śmieszek A, Szłapka J.[This corrects the article DOI: 10.1155/2016/3718468.].