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Topic:Magnetic Resonance Imaging

Magnetic Resonance Imaging (MRI) is a non-invasive diagnostic tool used in veterinary medicine to obtain detailed images of the internal structures of horses. It utilizes strong magnetic fields and radio waves to create cross-sectional images, allowing for the examination of soft tissues, bones, and joints without the need for radiation. MRI is particularly useful for diagnosing conditions in areas that are challenging to assess with other imaging modalities, such as the hoof, distal limb, and head. This page compiles peer-reviewed research studies and scholarly articles that explore the application, techniques, and advancements in MRI technology for equine diagnostics, as well as its role in improving the understanding of equine anatomy and pathology.
Time-of-flight magnetic resonance angiography (TOF-MRA) of the normal equine head.
Equine veterinary journal    September 4, 2012   Volume 45, Issue 2 187-192 doi: 10.1111/j.2042-3306.2012.00621.x
Manso-Díaz G, García-Real MI, Casteleyn C, San-Román F, Taeymans O.Noncontrast magnetic resonance angiography (MRA) is widely used in human and small animal medicine. However, this technique has not yet been described in the horse, and compared to other angiographic techniques MRA could be more cost efficient and potentially safer. Objective: The aim of this study was to provide a comprehensive anatomical reference of the normal equine head vasculature using a noncontrast MRA technique, on both low- and high-field MRI. Methods: Five healthy adult horses were examined, 4 with a low-field magnet (0.23T) and the remaining one with a high-field magnet (1.5T). The...
Eastern equine encephalitis: MRI findings in two patients.
Medicine and health, Rhode Island    August 30, 2012   Volume 95, Issue 7 227-229 
Ethier M, Rogg J.No abstract available
Evaluation of a diode laser for use in induction of tendinopathy in the superficial digital flexor tendon of horses.
American journal of veterinary research    August 29, 2012   Volume 73, Issue 9 1435-1444 doi: 10.2460/ajvr.73.9.1435
Vallance SA, Vidal MA, Whitcomb MB, Murphy BG, Spriet M, Galuppo LD.To evaluate use of a diode laser to induce tendinopathy in the superficial digital flexor tendon (SDFT) of horses. Methods: 4 equine cadavers and 5 adult horses. Methods: Cadaveric SDFT samples were exposed to a diode laser at various energy settings to determine an appropriate energy for use in in vivo experiments; lesion size was assessed histologically. In vivo experiments involved laser energy induction of lesions in the SDFT (2 preliminary horses [0, 25, 75, and 87.5 J] and 3 study horses [0 and 125 J]) and assessment of lesions. Study duration was 21 days, and lesions were assessed clini...
The effect of varying echo time using T2-weighted FSE sequences on the magic angle effect in the collateral ligaments of the distal interphalangeal joint in horses. Werpy NM, Ho CP, Garcia EB, Kawcak CE.Eight skeletally mature equine cadaver distal forelimbs were imaged using T2-weighted fast spin echo (FSE) sequences in a 1.0 T horizontal bore magnet. Each limb was parallel to the main magnetic field and with 16° angulation of the limb relative to the main magnetic field, which places one of the collateral ligaments of the distal interphalangeal joint at or near the magic angle. Each limb was imaged using an echo time (TE) of 80, 100, 120, and 140 ms. Reversal of the magic angle effect was achieved at echo time of 140 ms. However, given the alterations in tissue contrast and subjective decr...
A descriptive study of the equine proximal interphalangeal joint using magnetic resonance imaging, contrast arthrography, and arthroscopy.
Veterinary surgery : VS    August 14, 2012   Volume 41, Issue 6 677-684 doi: 10.1111/j.1532-950X.2012.00981.x
Kamm JL, Goodrich LR, Werpy NM, McIlwraith CW.To describe regions of the thoracic and pelvic limb proximal interphalangeal (PIP) joints that are arthroscopically accessible and identify soft tissue structures that should be avoided during arthroscope and instrument placement. Methods: Experimental ex vivo descriptive study. Methods: Horses (n = 15). Methods: Cadaver limbs (n = 36) were used for anatomic modeling, magnetic resonance imaging (MRI) with MRI-compatible needles, computed tomography with contrast arthrography, and arthroscopy of the PIP joint. Two arthroscopic approaches to the dorsal joint pouch were compared. Results: With ar...
Clinical significance and prognosis of deep digital flexor tendinopathy assessed over time using MRI. Vanel M, Olive J, Gold S, Mitchell RD, Walker L.Deep digital flexor (DDF) tendinopathy is one of the most frequent causes of foot lameness and the prognosis is guarded. The progress of lesion healing may be followed by magnetic resonance (MR) imaging to formulate a prognosis and to adapt the rehabilitation program. We assessed the correlation of outcome with total tendon damage and temporal resolution of MR abnormalities. Images from 34 horses with DDF tendinopathy that had undergone at least two low-field standing MR examinations of the foot (mean 2.5 ± 1.3 times) were reviewed. No horse having a T1-GRE hyperintense lesion over 30 mm in l...
Magnetic resonance imaging of navicular bursa adhesions. Holowinski ME, Solano M, Maranda L, García-López JM.Adhesions occur in the navicular bursa between the deep digital flexor tendon (DDFT) and other structures. Our objectives were to describe the appearance of navicular bursa adhesions on high-field magnetic resonance (MR) images, to compare these findings to findings at navicular bursoscopy, and to determine the prevalence of lesions in the remainder of the podotrochlear apparatus. Sixteen forelimbs from 14 horses that underwent MR imaging and navicular bursoscopy were evaluated. Adhesions were considered type 1 when characterized by a discontinuity in the navicular bursa fluid signal between t...
Magic angle magnetic resonance imaging of diode laser induced and naturally occurring lesions in equine tendons. Spriet M, Murphy B, Vallance SA, Vidal MA, Whitcomb MB, Wisner ER.Magic angle magnetic resonance (MR) imaging consists of imaging tendons at 55° to the magnetic field. In people, magic angle MR imaging is valuable for detection of chronic tendon lesions and allows calculation of tendon T1 values. Increased T1 values occur in people with chronic tendinopathy. The T1 values of normal equine tendons have been reported but there are no available data for abnormal equine tendons. Twelve limbs were studied. Two limbs had diode laser tendon lesions induced postmortem, four limbs had diode laser tendon lesions induced in vivo and six limbs had naturally occurring t...
The use of magnetic resonance imaging in evaluating horses with spinal ataxia. Mitchell CW, Nykamp SG, Foster R, Cruz R, Montieth G.To determine the accuracy of magnetic resonance imaging for diagnosing cervical stenotic myelopathy in horses, 39 horses with spinal ataxia and 20 control horses underwent clinical and neurologic examinations, cervical radiographs, euthanasia, magnetic resonance (MR) imaging of the cervical spine and necropsy. Twenty-four horses were diagnosed with cervical stenotic myelopathy, 5 with cervical vertebral stenosis, 7 with idiopathic ataxia, 3 horses had other causes of ataxia, and 20 were controls. The MR images were assessed for spinal cord intensity changes, presence of spinal cord compression...
Comparison of radiography, nuclear scintigraphy, and magnetic resonance imaging for detection of specific conditions of the distal tarsal bones of horses: 20 cases (2006-2010).
Journal of the American Veterinary Medical Association    April 21, 2012   Volume 240, Issue 9 1109-1114 doi: 10.2460/javma.240.9.1109
Daniel AJ, Judy CE, Rick MC, Saveraid TC, Herthel DJ.To describe pathological findings identified with MRI in the distal tarsal bones of horses with unilateral hind limb lameness attributable to tarsal pain and to compare the usefulness of MRI with that of radiography and nuclear scintigraphy in evaluation of this region. Methods: Retrospective case series. Methods: 20 lame horses. Methods: In all horses, MRI, radiography (4 standard projections), and nuclear scintigraphy of the tarsus had been performed. Horses were excluded if the results of all 3 imaging modalities were not available or if lameness was detected in more than 1 limb. Pathologic...
Comparison between magnetic resonance imaging and histological findings in the navicular bone of horses with foot pain.
Equine veterinary journal    April 12, 2012   Volume 44, Issue 6 692-698 doi: 10.1111/j.2042-3306.2012.00565.x
Dyson S, Blunden T, Murray R.There is limited knowledge about both histological features in early navicular disease and what histological features are represented by increased signal intensity in fat-suppressed magnetic resonance (MR) images of the navicular bone. Objective: To characterise increased signal intensity in the spongiosa of the navicular bone in fat-suppressed MR images and to compare this with histopathology; and to compare objective grading of all aspects of the navicular bone on MR images with histological findings. Methods: One or both front feet of 22 horses with foot pain and a median lameness duration ...
Reliability of high- and low-field magnetic resonance imaging systems for detection of cartilage and bone lesions in the equine cadaver fetlock.
Equine veterinary journal    March 21, 2012   Volume 44, Issue 6 684-691 doi: 10.1111/j.2042-3306.2012.00561.x
Smith MA, Dyson SJ, Murray RC.To determine the reliability of 2 magnetic resonance imaging (MRI) systems for detection of cartilage and bone lesions of the equine fetlock. Objective: To test the hypotheses that lesions in cartilage, subchondral and trabecular bone of the equine fetlock verified using histopathology can be detected on high- and low-field MR images with a low incidence of false positive or negative results; that low-field images are less reliable than high-field images for detection of cartilage lesions; and that combining results of interpretation from different pulse sequences increases detection of cartil...
Identification of a periorbital wooden foreign body as the cause of chronic ocular discharge in a horse.
Australian veterinary journal    February 22, 2012   Volume 90, Issue 3 84-87 doi: 10.1111/j.1751-0813.2011.00876.x
Santos M, Gutierrez-Nibeyro S, Stewart A, Hyde R, Rodgerson D.The clinical, diagnostic and therapeutic features of a horse with a wooden foreign body embedded in the deep portion of the right masseter muscle adjacent to the right orbit are presented. The purpose of this report is to describe the clinical presentation, magnetic resonance imaging findings and treatment of a penetrating wooden foreign body in a horse that had no history of trauma or evidence of a puncture wound. This report documents the usefulness of magnetic resonance imaging to detect a wooden foreign body embedded in the soft tissues of a horse with a chronic copious ocular discharge. T...
Standing low-field magnetic resonance imaging in horses with chronic foot pain.
Australian veterinary journal    February 22, 2012   Volume 90, Issue 3 75-83 doi: 10.1111/j.1751-0813.2011.00875.x
Gutierrez-Nibeyro S, Werpy N, White Ii N.Conventional imaging modalities can diagnose the source of foot pain in most cases, but have limitations in some horses, which can be overcome by using magnetic resonance imaging (MRI). However, there are no reports of the MRI appearance and prevalence of foot lesions of a large series of horses with chronic foot lameness. Methods: In the present study, 79 horses with unilateral or bilateral forelimb lameness because of chronic foot pain underwent standing low-field MRI to make a definitive diagnosis. Results: Of the 79 horses, 74 (94%) had alterations in >1 structure in the lame or lamest foo...
The role of diffusion in ferritin-induced relaxation enhancement of protons.
Journal of magnetic resonance (San Diego, Calif. : 1997)    February 22, 2012   Volume 217 36-40 doi: 10.1016/j.jmr.2012.02.005
Boss MA, Chris Hammel P.The influence of proton diffusion on nuclear magnetic resonance (NMR) relaxation was investigated in the presence of horse spleen ferritin at 7 T. Binary mixtures of water and glycerol were used to control diffusion within the range of 0.6-2.0 × 10(-9)m(2)/s, which was confirmed by pulsed gradient techniques. The effect of chemical exchange by hydrolysis between water and glycerol on relaxation was characterized with Carr-Purcell-Meiboom-Gill (CPMG) dispersion experiments. The relaxation rate enhancement of the protons due to ferritin was found to be inversely proportional to the diffusion co...
Characterization of the origin and body of the normal equine rear suspensory ligament using ultrasonography, magnetic resonance imaging, and histology. Schramme M, Josson A, Linder K.The suspensory ligament is difficult to image accurately, partly because it contains ligamentous fibers, as well as noncollagenous adipose and muscle tissue in the normal horse. Our hypothesis was that magnetic resonance (MR) imaging would be more accurate than ultrasonography in identifying the size of the suspensory ligament and the presence and size of noncollagenous tissues within the ligament. Eleven horses were used for ultrasonographic and MR imaging and histologic evaluation of the rear suspensory ligament. The origin and body of the normal suspensory ligament had a heterogenous appear...
Magnetic resonance imaging-detected adaptation and pathology in the distal condyles of the third metacarpus, associated with lateral condylar fracture in Thoroughbred racehorses.
Equine veterinary journal    January 19, 2012   Volume 44, Issue 6 699-706 doi: 10.1111/j.2042-3306.2011.00535.x
Tranquille CA, Parkin TD, Murray RC.Lateral condylar (LC) fractures of the third metacarpus (McIII) are a common reason for euthanasia in racehorses, and may be the result of repetitive overloading or cumulative pathological change. Magnetic resonance imaging (MRI) allows monitoring of bone and cartilage to detect pathological and adaptive changes that may be precursors of fracture. Objective: To describe bone and cartilage MRI features in the distal condyles of McIII of Thoroughbred racehorses, with and without condylar fracture. Objective: 1) A greater degree of bone and cartilage adaptation or pathology will be seen in fractu...
The influence of temperature and age on the T1 relaxation time of the equine distal limb. Adrian AM, Koene M, Roberts S, Doughty P, Bolas N, Kinns J, Brehm W, Gerlach K.The extent of fat suppression using short tau inversion recovery (STIR) imaging is variable between horses. Our aim was to determine if patient's age and/or hoof temperature have an influence on the T(1) relaxation time of bone marrow in the equine distal limb, thereby affecting the suppression of fat signal. Magnetic resonance imaging was conducted on standing horses and cadaver samples using a low-field magnet (0.27 T). The hoof temperature was measured at the lateral side of the coronary band. A modified inversion recovery fast spin-echo (IR-FSE) sequence was used to measure the signal inte...
Conservative management of a transverse fracture of the distal phalanx in a Quarter Horse.
Journal of the American Veterinary Medical Association    December 17, 2011   Volume 240, Issue 1 82-86 doi: 10.2460/javma.240.1.82
Sherlock CE, Eggleston RB, Howerth EW.A 7-year-old Quarter Horse gelding was evaluated because of sudden onset of severe left forelimb lameness of 4 days' duration. Results: Clinical evaluation and diagnostic perineural analgesia localized the lameness to the distal portion of the left forelimb. Radiography revealed a transverse fracture of the distal phalanx of the left forelimb. Results: The horse was treated conservatively with stall rest and stabilization of the hoof with fiberglass cast material and an elevated heel support. These treatments improved the lameness considerably. Over the following 4 months, the horse was exerci...
Detection of articular pathology of the distal aspect of the third metacarpal bone in thoroughbred racehorses: comparison of radiography, computed tomography and magnetic resonance imaging.
Veterinary surgery : VS    October 31, 2011   Volume 40, Issue 8 942-951 doi: 10.1111/j.1532-950X.2011.00881.x
O'Brien T, Baker TA, Brounts SH, Sample SJ, Markel MD, Scollay MC, Marquis P, Muir P.To compare digital radiography (DR), computed tomography (CT), and magnetic resonance imaging (MRI) for detection of pathology of the distal aspect of the third metacarpal bone (MC3) and to assess whether arthrography would improve detection of articular cartilage or subchondral bone cracking. Methods: Cross-sectional study. Methods: Limb specimens from 17 Thoroughbred horses after catastrophic injury and 4 age-matched control horses. Methods: Standard DR, CT, and MRI images of the metacarpophalangeal joint were acquired before and after iohexol injection. Pathologic features detected with ima...
Advanced imaging of the nervous system in the horse.
The Veterinary clinics of North America. Equine practice    October 21, 2011   Volume 27, Issue 3 439-453 doi: 10.1016/j.cveq.2011.08.009
Scrivani PV.Neuroimaging underwent a dramatic revolution during the past few decades due to the development of new technologies that produce exquisite images of patient morphology and function, new technologies that store and distribute information more efficiently, and research that has improved understanding of pathogenesis and effective clinical use of new imaging methods. Advanced equine neuroimaging is a specialized field with unique challenges associated with patient size, availability of equipment, using equipment designed for humans, small sample size for various diseases, and issues associated wi...
Standing low-field magnetic resonance imaging appearance of normal collateral ligaments of the equine distal interphalangeal joint. Gutierrez-Nibeyro SD, Werpy NM, White NA, McCutcheon J, Weng HY, Christopher JM.High- and low-field magnetic resonance (MR) imaging systems are available for clinical diagnosis of collateral desmopathy of the equine distal interphalangeal joint (DIJ). Knowledge of the normal appearance, size, shape,and signal variation of these ligaments on high- and low-field MR images is essential when assessing desmopathy detected by MR imaging. However, there are no descriptions of the normal features of DIJ collateral ligaments on images obtained with a standing low-field MR system. Low-field MR imaging characteristics of normal collateral ligaments of the DIJ of cadaver feet were co...
A collagenase gel/physical defect model for controlled induction of superficial digital flexor tendonitis.
Equine veterinary journal    September 25, 2011   Volume 44, Issue 5 576-586 doi: 10.1111/j.2042-3306.2011.00471.x
Watts AE, Nixon AJ, Yeager AE, Mohammed HO.A consistent and clinically relevant model for the induction of core lesions confined to the mid-metacarpal superficial digital flexor tendon (SDFT) has not been previously reported. Injection of bacterial collagenase is commonly used but often results in large, irregular and inconsistent lesions that disrupt the superficial tendon layers and epitenon. Objective: To develop and evaluate a new injection technique for collagenase induction of SDFT injury. Methods: Collagenase gel was injected into a physical columnar defect created by longitudinally placing a curved 16 gauge 8.89 cm needle in ...
Magnetic resonance imaging findings in the carpus and proximal metacarpal region of 50 lame horses.
Equine veterinary journal    September 6, 2011   Volume 44, Issue 2 163-168 doi: 10.1111/j.2042-3306.2011.00422.x
Nagy A, Dyson S.There is limited information on magnetic resonance imaging (MRI) findings in the carpus and proximal metacarpal region of lame horses. Objective: To document MRI findings in horses with lameness localised to the carpus and/or proximal metacarpal region. Methods: Clinical records of horses that underwent MRI of the carpus and/or proximal metacarpal region at the Animal Health Trust between January 2003 and September 2010 were reviewed. Magnetic resonance images of all horses and available radiographs, ultrasonographic and scintigraphic images were assessed. When possible, MRI findings were rela...
Evaluation of intra-articular mesenchymal stem cells to augment healing of microfractured chondral defects. McIlwraith CW, Frisbie DD, Rodkey WG, Kisiday JD, Werpy NM, Kawcak CE, Steadman JR.This study evaluated intra-articular injection of bone marrow-derived mesenchymal stem cells (BMSCs) to augment healing with microfracture compared with microfracture alone. Methods: Ten horses (aged 2.5 to 5 years) had 1-cm2 defects arthroscopically created on both medial femoral condyles of the stifle joint (analogous to the human knee). Defects were debrided to subchondral bone followed by microfracture. One month later, 1 randomly selected medial femorotibial joint in each horse received an intra-articular injection of either 20 × 10(6) BMSCs with 22 mg of hyaluronan or 22 mg of hyalurona...
Endoscopic evaluation of the navicular bursa: observations, treatment and outcome in 92 cases with identified pathology.
Equine veterinary journal    August 18, 2011   Volume 44, Issue 3 339-345 doi: 10.1111/j.2042-3306.2011.00443.x
Smith MR, Wright IM.Diagnostic navicular bursoscopy has been described in limited cases. Review of greater numbers is needed to define its contribution to case management and prognostic values. Objective: To report: 1) clinical, diagnostic and endoscopic findings in a series of cases, 2) surgical techniques and case outcomes and 3) prognostic values. The authors hypothesise: 1) lameness localising to the navicular bursa is commonly associated with dorsal border deep digital flexor tendon (DDFT) lesions, 2) endoscopy allows extent of injuries to be assessed and treated, 3) case outcome relates to severity of DDFT ...
Magnetic resonance imaging findings of equine solar penetration wounds. del Junco CI, Mair TS, Powell SE, Milner PI, Font AF, Schwarz T, Weaver MP.The magnetic resonance (MR) imaging features, signalment, clinical history and outcome of 55 horses with a penetrating sole injury were evaluated. Our aim was to describe MR imaging findings within the hoof capsule, assess the utility of the technique and give recommendations for the optimal MR imaging protocol to evaluate such injuries. Data from five equine hospitals were analyzed retrospectively. The tract was more likely to be visualized in animals scanned within the first week postinjury. There was no significant predisposition based on breed, age, or gender. T2*W transverse sequences wer...
Clinical and diagnostic imaging findings in horses with subchondral bone trauma of the sagittal groove of the proximal phalanx. Dyson S, Nagy A, Murray R.Eight sports horses with unilateral (4) or bilateral (3) forelimb or unilateral hindlimb (1) lameness had subtle radiologic abnormalities of the subchondral bone of the sagittal groove of the proximal phalanx associated with moderate or intense increased radiopharmaceutical uptake. High-field or low-field magnetic resonance (MR) imaging confirmed the presence of a fissure fracture or subchondral and trabecular bone trauma. Seven of eight lesions were located approximately midway between the dorsal and palmar cortices of the proximal phalanx; the eighth was sited more dorsally. Two horses under...
The value of radiographic screening for metallic particles in the equine foot and size of related artifacts on low-field MRI. Urraca del Junco CI, Shaw DJ, Weaver MP, Schwarz T.Magnetic susceptibility artifacts as a result of metal debris from shoeing are a common problem in magnetic resonance imaging of the equine foot. Our purpose was to determine the suitability of radiography as a screening tool for the presence and location of metallic particles in the equine foot and to predict the size of the resultant magnetic susceptibility artifact. Radiography had 100% sensitivity for detection of metal particles > or = 1 mm diameter. Metal particles of known diameter were placed within the hoof wall of 22 cadaver feet and scanned with a low-field strength MR imaging un...
Computed tomography or magnetic resonance imaging-assisted partial hoof wall resection for keratoma removal.
Veterinary surgery : VS    July 19, 2011   Volume 40, Issue 6 708-714 doi: 10.1111/j.1532-950X.2011.00864.x
Getman LM, Davidson EJ, Ross MW, Leitch M, Richardson DW.To (1) describe the computed tomography (CT) and magnetic resonance imaging (MRI) appearance of keratomas; (2) describe a CT- or MRI-assisted partial hoof wall resection technique for removal of keratomas; and (3) evaluate the morbidity and postoperative outcome of these horses. Methods: Case series. Methods: Horses (n=10) with keratoma. Methods: Data retrieved from medical records included signalment, lameness duration and grade, physical and diagnostic evaluation findings, CT and MRI technique and findings, surgical details, histopathologic diagnosis, postoperative treatment, and complicatio...
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