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Topic:Risk Factors

Risk factors in horses refer to variables or conditions that increase the likelihood of disease, injury, or other adverse health outcomes in equine populations. These factors can be intrinsic, such as age, breed, and genetic predisposition, or extrinsic, including environmental conditions, management practices, and exposure to infectious agents. Understanding risk factors is important for developing preventive strategies and improving health management in horses. This page aggregates peer-reviewed research studies and scholarly articles that explore the identification, assessment, and mitigation of risk factors in equine health, with the aim of enhancing disease prevention and promoting overall well-being in horses.
First report of genetic diversity and risk factor analysis of equine piroplasm infection in equids in Jilin, China.
Parasites & vectors    September 9, 2020   Volume 13, Issue 1 459 doi: 10.1186/s13071-020-04338-1
Zhao S, Wang H, Zhang S, Xie S, Li H, Zhang X, Jia L.Equine piroplasmosis (EP) is a tick-borne hemoprotozoan disease of equids, caused by Theileria equi and Babesia caballi. Equine piroplasmosis represents a serious challenge to the equine industry due to important economic losses worldwide. The present study aimed to evaluate the prevalence of Theileria equi and Babesia caballi infections in equids from Jilin Province, China. Methods: A total of 220 blood samples (192 horses and 28 donkeys/mules) were collected from March 2018 to October 2019 in five districts of Jilin Province and analyzed by PCR. Potential risk factors, including the region, ...
Epidemiological and Molecular Investigation of Ocular Fungal Infection in Equine from Egypt.
Veterinary sciences    September 8, 2020   Volume 7, Issue 3 130 doi: 10.3390/vetsci7030130
Tahoun A, Elnafarawy HK, Elmahallawy EK, Abdelhady A, Rizk AM, El-Sharkawy H, Youssef MA, El-Khodery S, Ibrahim HMM.Diagnosis and treatment of ocular fungal infection in equine seems very challenging for owners and clinicians. The present study aimed to identify and characterize fungal species isolated from the eyes of clinically healthy and diseased equines (N = 100) from Dakahlia Governorate, Egypt. The work also involved morphological and molecular characterization of the major fungal species. In addition, correlations between the occurrence of isolated fungi and some of the potential risk factors were also investigated. Interestingly, the prevalence rate of ocular mycosis in all examined equines in the ...
Serological evidence of co-circulation of West Nile and Usutu viruses in equids from western Spain.
Transboundary and emerging diseases    September 5, 2020   Volume 68, Issue 3 1432-1444 doi: 10.1111/tbed.13810
Guerrero-Carvajal F, Bravo-Barriga D, Martín-Cuervo M, Aguilera-Sepúlveda P, Ferraguti M, Jiménez-Clavero MÁ, Llorente F, Alonso JM, Frontera E.West Nile virus (WNV) is a mosquito-borne emerging virus in Europe with capacity to cause neurological complications such as encephalitis or meningoencephalitis in humans, birds or equids. In Spain, WNV is actively circulating in mosquitoes, birds and horses in different regions, but never has been deeply studied in Extremadura. Therefore, the aim of this study was to evaluate the seroprevalence of WNV in equids of those areas and to analyse the risk factors associated with exposure to the virus. A total of 199 out of 725 equids presented antibodies against WNV by competition ELISA (27.45%), w...
Association between the administration of phenylbutazone prior to racing and musculoskeletal and fatal injuries in Thoroughbred racehorses in Argentina.
Journal of the American Veterinary Medical Association    August 29, 2020   Volume 257, Issue 6 642-647 doi: 10.2460/javma.257.6.642
Zambruno T, Georgopoulos SP, Boden LA, Parkin TDH.To examine the association between prerace administration of phenylbutazone and the risk of musculoskeletal injury (MSI) and fatal injury in Thoroughbred racehorses that raced between 2006 and 2015 at 2 of the 4 official racetracks in Argentina. Methods: Data from racetrack databases and veterinary reports on 283,193 race starts. Methods: Data were collected relating to race performance and injury outcomes for starts at these tracks. The incidence of MSI and fatal injury was calculated for each year, stratified by the declared prerace administration of phenylbutazone. Univariable logistic regr...
Serological and Molecular Investigation of Brucellosis in Breeding Equids in Pakistani Punjab.
Pathogens (Basel, Switzerland)    August 19, 2020   Volume 9, Issue 9 673 doi: 10.3390/pathogens9090673
Hussain A, Jamil T, Tareen AM, Melzer F, Hussain MH, Khan I, Saqib M, Zohaib A, Hussain R, Ahmad W, Iqbal M, Neubauer H.Brucellosis is an important zoonosis worldwide. Equines are susceptible to the infection when in close contact with infected animals. The objective of our study was to update the existing knowledge and detect and differentiate the causative agent of brucellosis in breeding equines in Punjab, Pakistan. A cross-sectional study was designed to evaluate the occurrence and etiology of the infection in the equine population in three districts. A total of 448 equine sera were collected from three prefectures viz. Sahiwal, Khanewal, and Okara of the Punjab Province of Pakistan. Ninety-six (21.4%) samp...
Insight From Animals Resistant to Prion Diseases: Deciphering the Genotype – Morphotype – Phenotype Code for the Prion Protein.
Frontiers in cellular neuroscience    August 18, 2020   Volume 14 254 doi: 10.3389/fncel.2020.00254
Myers R, Cembran A, Fernandez-Funez P.Prion diseases are a group of neurodegenerative diseases endemic in humans and several ruminants caused by the misfolding of native prion protein (PrP) into pathological conformations. Experimental work and the mad-cow epidemic of the 1980s exposed a wide spectrum of animal susceptibility to prion diseases, including a few highly resistant animals: horses, rabbits, pigs, and dogs/canids. The variable susceptibility to disease offers a unique opportunity to uncover the mechanisms governing PrP misfolding, neurotoxicity, and transmission. Previous work indicates that PrP-intrinsic differences (s...
Plate Removal after Internal Fixation of Limb Fractures: A Retrospective Study of Indications and Complications in 48 Horses.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    August 16, 2020   Volume 34, Issue 1 59-67 doi: 10.1055/s-0040-1714411
Donati B, Fürst AE, Del Chicca F, Jackson MA. The aim of this study was to determine the indications for, and complications of, plate removal surgery in horses that underwent internal fixation of limb fractures. Methods:  Medical records of horses presented to our hospital between 1990 and 2015 for the removal of plates after treatment of limb fractures were reviewed. Data collected at the time of initial presentation, including signalment, history, fracture features and treatment and information about the indications, timing and complications of implant removal were reviewed. Results:  The most common bones involved were the ulna ...
Complications Following Mandibular Cheek Tooth Extraction in 20 Horses.
Frontiers in veterinary science    August 13, 2020   Volume 7 504 doi: 10.3389/fvets.2020.00504
Gergeleit H, Bienert-Zeit A.The objectives of this retrospective study were to describe the prevalence and characteristics of post-operative complications that occur following equine mandibular cheek tooth extractions and to assess for possible associated risk factors. Clinically significant post-extraction complications necessitating repeat referral developed following 20/302 (6.6%) mandibular cheek tooth extractions. Horses developing complications were younger than the overall population having mandibular cheek teeth extractions and the most commonly affected teeth were the Triadan 07 s and 09 s. Alveolar sequestratio...
Prevalence of gastrointestinal nematodes, parasite control practices and anthelmintic resistance patterns in a working horse population in Egypt.
Equine veterinary journal    August 11, 2020   Volume 53, Issue 2 339-348 doi: 10.1111/evj.13325
Salem SE, Abd El-Ghany AM, Hamad MH, Abdelaal AM, Elsheikh HA, Hamid AA, Saud MA, Daniels SP, Ras R.Anthelmintic resistance is commonly reported in horse populations in developed countries, but evidence in some working horse populations is either lacking or inconclusive. Objective: To estimate prevalence of GI nematode infections in working horses in Egypt and to evaluate strongyle resistance to ivermectin, doramectin and fenbendazole. Methods: Cross-sectional study. Methods: Faecal egg count was performed on 644 working horses from 2 provinces in Egypt. A short questionnaire about horse signalment and worming history was completed for each horse. Horses identified with ≥50 strongyle type ...
Seroprevalence and evaluation of risk factors associated with seropositivity for Borrelia burgdorferi in Ontario horses.
Equine veterinary journal    July 29, 2020   Volume 53, Issue 2 331-338 doi: 10.1111/evj.13317
Neely M, Arroyo LG, Jardine C, Moore A, Hazlett M, Clow K, Archer H, Weese JS.Recently, the blacklegged tick (Ixodes scapularis), which is the vector of Borrelia burgdorferi, has undergone a range expansion from the northeastern and mid-west United States to areas of southeastern Canada, including parts of Ontario. Understanding the seroprevalence of antibodies against B. burgdorferi in horses and risk factors for exposure is important for monitoring and preventing this emerging disease. Methods: Cross-sectional study of 551 horses in southern, central, and eastern Ontario, Canada. Objective: To assess the seroprevalence of B. burgdorferi in horses in Ontario, Canada; ...
Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners.
The Veterinary record    July 27, 2020   Volume 187, Issue 10 404 doi: 10.1136/vr.105880
Bowden A, Boynova P, Brennan ML, England GCW, Mair TS, Furness WA, Freeman SL, Burford JH.The study aim was to describe conditions seen 'out-of-hours' in equine practice. This was a retrospective case series of first opinion 'out-of-hours' cases seen at two equine practices between 2011 and 2013. Data were retrieved on case presentation, diagnostic testing, treatment administered and outcome, and diseases categorised using a systems-based coding system. A hierarchical logistic regression, formulated using a generalised linear model, was used to identify clinical variables associated with a binary outcome of 'critical' cases (required hospitalisation or euthanasia or died). Data fro...
A retrospective evaluation of the effect of perianesthetic hydromorphone administration on the incidence of postanesthetic signs of colic in horses.
Veterinary anaesthesia and analgesia    July 23, 2020   Volume 47, Issue 6 757-762 doi: 10.1016/j.vaa.2020.06.003
Skrzypczak H, Reed R, Barletta M, Quandt J, Sakai D.To describe the incidence of postanesthetic signs of colic (PASC) in horses and determine if perianesthetic administration of hydromorphone was associated with an increased risk of PASC. Methods: Retrospective, cohort study. Methods: A total of 409 horses. Methods: Anesthesia and clinical records of horses admitted for various procedures from July 2018 to September 2019 were reviewed. Signs of colic and interventions were recorded up to 48 hours after anesthesia. A binomial logistic regression model was used to evaluate the association between the type of surgery, administration of hydromorpho...
Retrospective analysis of 15 years of horse-related maxillofacial fracture data at a major German trauma center.
European journal of trauma and emergency surgery : official publication of the European Trauma Society    July 22, 2020   Volume 48, Issue 4 2539-2546 doi: 10.1007/s00068-020-01450-w
Stier R, Tavassol F, Dupke C, Rüter M, Jehn P, Gellrich NC, Spalthoff S.The purpose of this study was to estimate the effect of the mechanism of trauma (fall versus kick), rider demographics, equestrian experience, protective equipment, and whether or not a horse was shod on the anatomic site of a horse-related maxillofacial fracture, operating time, postoperative complication rate, and length of hospital stay. Methods: We retrospectively reviewed the medical records of patients treated for horse-related maxillofacial fractures at a single institution in Germany between January 2000 and March 2015. We used linear and logistic regression to test the above-mentioned...
Influence of specific management practices on blood selenium, vitamin E, and beta-carotene concentrations in horses and risk of nutritional deficiency.
Journal of veterinary internal medicine    July 20, 2020   Volume 34, Issue 5 2132-2141 doi: 10.1111/jvim.15862
Pitel MO, McKenzie EC, Johns JL, Stuart RL.Selenium or alpha-tocopherol deficiency can cause neuromuscular disease. Beta-carotene has limited documentation in horses. Objective: To evaluate the effect of owner practices on plasma beta-carotene concentration and risk of selenium and alpha-tocopherol deficiencies. Methods: Three-hundred and forty-nine adult (≥1 year), university and privately owned horses and mules. Methods: Cross-sectional study. Whole blood selenium, plasma alpha-tocopherol, and plasma beta-carotene concentrations were measured once. Estimates of daily selenium and vitamin E intake, pasture access, and exercise loa...
Infection dynamics of Theileria equi in carrier horses is associated with management and tick exposure.
Ticks and tick-borne diseases    July 11, 2020   Volume 11, Issue 6 101508 doi: 10.1016/j.ttbdis.2020.101508
Tirosh-Levy S, Gottlieb Y, Mazuz ML, Savitsky I, Steinman A.The tick-borne equine hemoparasite, Theileria equi, is endemic in many parts of the world where prevalence may be high, and most infected horses are apparently healthy but serve as life-long carriers. To determine the factors that affect T. equi dynamics, we followed parasitic loads in apparently healthy horses at four time points during one year. A total of 1094 blood samples were collected from 395 horses, along with ticks and demographic and clinical data. Infection and load of T. equi were tested by PCR and qPCR, and for the spring dataset, infection was also tested serologically by IFAT (...
Conditions predict heightened Hendra virus spillover risk in horses this winter: actions now can change outcomes.
Australian veterinary journal    July 1, 2020   Volume 98, Issue 6 270-271 doi: 10.1111/avj.12964
Eby P, Plowright RK, McCallum H, Peel AJ.No abstract available
Correlation Between Serum Activity of Muscle Enzymes and Stage of the Estrous Cycle in Italian Standardbred Horses Susceptible to Exertional Rhabdomyolysis.
Journal of equine veterinary science    June 25, 2020   Volume 92 103175 doi: 10.1016/j.jevs.2020.103175
Pasolini MP, Pezzella R, Santoro P, Cocchia N, Greco M, Del Prete C, Della Valle G, Auletta L.Equine exertional rhabdomyolysis (ER) is a well-recognized clinical syndrome affecting racehorses. Prevalence analysis of ER showed that female sex was a significant risk factor. The aim of this research was to evaluate the differences and correlations in the serum activity of muscle enzymes and the stage of the estrous cycle in ER-susceptible and control (C) mares. Serum muscle enzyme activity before and after exercise and sex hormones were analyzed in the two groups of mares. Ten cyclic ER and 10 cyclic C mares were examined weekly for 4 weeks. During diestrus, ER horses had significantly hi...
High Frequencies of TNC and COL5A1 Genotypes Associated With Low Risk for Superficial Digital Flexor Tendinopathy in Greek Indigenous Horse Breeds Compared With Warmblood Horses.
Journal of equine veterinary science    June 20, 2020   Volume 92 103173 doi: 10.1016/j.jevs.2020.103173
Giantsis IA, Diakakis NE, Avdi M.Tendinopathies constitute a very common category of musculoskeletal disorders, causing economic losses in the equine industry and animal welfare issues in horse populations. Sport and racehorses are in general sensitive to tendinopathies, whereas local indigenous horse populations are often more tolerant to various disorders. Particularly, indigenous Greek horse breeds have evolved and adapted in the rough topographic features of mountainous and semimountainous Greek terrain and are less prone to develop tendinopathies. Susceptibility to tendinopathy has been proposed to be associated with thr...
Molecular evidence of Babesia caballi and Theileria equi in equines and ticks in Nigeria: prevalence and risk factors analysis.
Parasitology    June 17, 2020   Volume 147, Issue 11 1238-1248 doi: 10.1017/S0031182020000992
Onyiche TE, Taioe MO, Ogo NI, Sivakumar T, Biu AA, Mbaya AW, Xuan X, Yokoyama N, Thekisoe O.Babesia caballi and Theileria equi are biological agents responsible for equine piroplasmosis (EP). We conducted a robust and extensive epidemiological study in Nigeria on the prevalence and risk factors of EP. Blood (468, both horses and donkeys) and ticks (201 pools) were screened using polymerase chain reaction (PCR). DNA of equine piroplasms was observed in tick pools with B. caballi amplified in Rhipicephalus evertsi evertsi only [minimum infection rate (MIR) of 7.6%] while T. equi was observed in R. e. evertsi (MIR, 61.6%), Hyalomma dromedarii (MIR, 23.7%) and H. truncatum (MIR, 50.0%). ...
Science-in-brief: Risk assessment for reducing injuries of the fetlock bones in Thoroughbred racehorses.
Equine veterinary journal    June 12, 2020   Volume 52, Issue 4 482-488 doi: 10.1111/evj.13273
Colgate VA, Marr CM.No abstract available
Molecular Analysis and Risk Factors Associated With Theileria equi Infection in Domestic Donkeys and Mules of Punjab, Pakistan.
Journal of equine veterinary science    June 12, 2020   Volume 92 103164 doi: 10.1016/j.jevs.2020.103164
Shah MH, Ijaz M, Ahmed A, Aziz MU, Ghaffar A, Ghauri HN, Naveed M.Theileriosis is an important disease of economic significance which badly affects the equine husbandry of developing countries. The present study was planned to investigate the molecular prevalence of theileriosis, associated risk factors, and alterations in hematological parameters of donkeys and mules from district Mianwali, Punjab, Pakistan. Blood samples from 150 equids (n = 75 donkeys; n = 75 mules) were examined microscopically, and the genomic DNA from each sample was processed for the amplification of the 18S rRNA gene of Theileria. The polymerase chain reaction confirmed isolates we...
Citizens’ juries give verdict on whether private practice veterinarians should attend unvaccinated Hendra virus suspect horses.
Australian veterinary journal    June 11, 2020   Volume 98, Issue 7 273-279 doi: 10.1111/avj.12957
Annand EJ, Reid PA, Johnson J, Gilbert GL, Taylor M, Walsh M, Ward MP, Wilson A, Degeling C.Hendra virus (HeV) is endemic in Australian flying foxes, posing a threat to equine and human health. Equine vaccination remains the most effective risk mitigation strategy. Many horses remain unvaccinated - even in higher-risk regions. Debate surrounding the vaccine's use is characterised by conflicting perspectives, misunderstanding and mistrust. Private veterinary practitioners are critical to early identification of public health risk through recognition, sampling and management of suspect-equine-HeV-cases. However, managing such cases can be burdensome, with some veterinarians opting not ...
Incorporation of Equine Learning Theory into the Undergraduate Curriculum.
Journal of veterinary medical education    June 9, 2020   Volume 48, Issue 3 351-360 doi: 10.3138/jvme-2019-0078
Pearson G, Connor M, Keen J, Reardon R, Waran N.Working as an equine veterinarian carries a high risk of occupational injury, with the behavior of the horse frequently reported as a cause for these injuries. Risk of injury is one reason cited by undergraduate veterinary students that would prevent them from entering large animal practice, and newly graduated veterinarians have been shown to be at increased risk of sustaining an occupational injury compared with more experienced colleagues. A cohort of pre-final-year undergraduate veterinary students were given a 45-minute lecture on learning theory and its application in equine practice, co...
Age, gender and climate associations with the seroprevalence of Neospora species infection in horses in Jordan. Abu-Halaweh M, Abo-Shehada MN, Khalil R.A cross-sectional study was carried out on a sample of 379 horses to determine the seroprevalence of Neospora spp. in Jordan using the indirect fluorescent antibody test. Five variables, namely locality (n=10), climatic zone (n=4), age group (n=3), gender, and breed were tested as risk factors for Neospora-immunoglobulin (Ig)G seropositivity at four cutoff titers (1:50, 1:200, 1:400, and 1:800) using univariate and multivariate logistic regression analyses. A total of 122 (32%; 95% CI: 28, 37) sera samples had anti-Neospora-IgG at a cutoff titer of 1:50. Increased Neospora-IgG seropositivity w...
National Seroprevalence and Risk Factors for Eastern Equine Encephalitis and Venezuelan Equine Encephalitis in Costa Rica.
Journal of equine veterinary science    June 2, 2020   Volume 92 103140 doi: 10.1016/j.jevs.2020.103140
León B, Käsbohrer A, Hutter SE, Baldi M, Firth CL, Romero-Zúñiga JJ, Jiménez C.Eastern equine encephalitis and Venezuelan equine encephalitis are endemic neglected tropical diseases in the Americas, causing encephalitis in both horses and humans. In 2013, a cross-sectional study was performed in 243 horses located in the highlands and lowlands throughout Costa Rica. Serum samples were analyzed with an IgG ELISA and confirmed by the plaque-reduction neutralization test (PRNT80). Venezuelan equine encephalitis virus (VEEV) and Eastern equine encephalitis virus (EEEV) overall seroprevalences by the PRNT80 were 36% (95% confidence interval [CI]: 29.9-42.5; 78/217 horses) and...
Incidence and risk factors for race-day jockey falls over fourteen years.
Journal of science and medicine in sport    May 21, 2020   Volume 23, Issue 12 1154-1160 doi: 10.1016/j.jsams.2020.05.015
Legg KA, Cochrane DJ, Bolwell CF, Gee EK, Rogers CW.To determine the incidence of, and risk factors for, race-day jockey falls occurring in Thoroughbred flat and jumps (hurdle and steeplechase) racing. Methods: Retrospective cohort study. Methods: Incidence rates for race-day jockey falls over 14 racing seasons in New Zealand (n=421,596 race-day starts) were calculated per 1000 rides. Univariable and multivariable analyses of jockey, horse and race level risk factors were conducted with Poisson regression in a generalized linear mixed model. Results: Most races (97%, n=407,948 race starts) were flat racing with 10 races/race-day, whilst most ju...
Concussion knowledge, attitudes and behaviour in equestrian athletes.
Journal of science and medicine in sport    May 17, 2020   Volume 23, Issue 11 1055-1061 doi: 10.1016/j.jsams.2020.05.008
Theadom A, Reid D, Hardaker N, Lough J, Hume PA.To determine knowledge, attitudes and behaviour towards concussion in adult equestrian athletes. Methods: Nationwide, cross-sectional, questionnaire. Methods: Participants were recruited via advertisements circulated through social media, community presentations and equestrian organisations. Participants were sent a web link to an online questionnaire previously designed for high school athletes and modified to ensure relevance to equestrian activities. The percentage of correct responses per item and a total knowledge score were calculated. Differences in concussion knowledge by age, sex, lev...
Environmental surveillance and adverse neonatal health outcomes in foals born near unconventional natural gas development activity.
The Science of the total environment    May 5, 2020   Volume 731 138497 doi: 10.1016/j.scitotenv.2020.138497
Mullen KR, Rivera BN, Tidwell LG, Ivanek R, Anderson KA, Ainsworth DM.Studies of neonatal health risks of unconventional natural gas development (UNGD) have not included comprehensive assessments of environmental chemical exposures. We investigated a clustering of dysphagic cases in neonatal foals born between 2014 and 2016 in an area of active UNGD in Pennsylvania (PA),USA. We evaluated equine biological data and environmental exposures on the affected PA farm and an unaffected New York (NY) farm owned by the same proprietor. Dams either spent their entire gestation on one farm or moved to the other farm in late gestation. Over the 21-month study period, physic...
Benefits and risks of barefoot harness racing in Standardbred trotters.
Animal science journal = Nihon chikusan Gakkaiho    May 5, 2020   Volume 91, Issue 1 e13380 doi: 10.1111/asj.13380
Solé M, Lindgren G, Bongcam-Rudloff E, Jansson A.There is a lack of research on the benefits and risks of shoeing conditions in harness racing. Thus, our objectives were to: (a) investigate whether velocity times (VT; s/km) are affected by racing unshod (N = 76,932 records on 5,247 horses); (b) determine the potential risks of galloping, being penalized, and disqualification when competing unshod (N = 111,755 records on 6,423 horses); and (c) identify additional environmental factors that affect VT and risks. VT was found to be significantly influenced by shoeing condition (e.g., unshod, shod front, shod hind, or fully shod), but also by...
Molecular Identification of Borrelia afzelii from Ticks Parasitizing Domestic and Wild Animals in South Korea.
Microorganisms    April 29, 2020   Volume 8, Issue 5 649 doi: 10.3390/microorganisms8050649
Seo MG, Kwon OD, Kwak D.Lyme borreliosis is one of the most prevalent tick-borne infectious zoonotic diseases caused by spirochetes of the sensu lato group. The present study assessed the risk factors and prevalence of Lyme borreliosis in ticks parasitizing domestic and wild animals. A total of 589 ticks (329 tick pools) collected from animals were identified as , (85.7%), (10.0%), and (4.3%) using morphological and molecular methods in South Korea. In this study, the 5S-23S gene sequences of (6/329, 1.8%) were detected in ticks taken from mammals, including ticks from horses (2/147 pools, 1.4%), wild boar (1/19 ...
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