Treatments for horses encompasses a range of medical and therapeutic interventions aimed at maintaining or restoring equine health. This field involves the use of pharmaceuticals, surgical procedures, and alternative therapies to address various conditions affecting horses. Common treatments include the administration of anti-inflammatory drugs, antibiotics, and vaccines, as well as physical therapies and nutritional management. Research in this area focuses on evaluating the efficacy, safety, and outcomes of different treatment modalities. This page collects peer-reviewed research studies and scholarly articles that explore the methods, advancements, and clinical outcomes associated with equine treatment practices.
Bossut DF, Page EH, Stromberg MW.Cutaneous pain thresholds to pinprick, pinch, and heat stimuli were quantified during control and electroacupuncture trials in 23 horses. Pain thresholds for 8 areas of the body during control trials (no needles) were statistically compared with pain thresholds measured in the same areas of the same horse when given electroacupuncture treatment. Statistically significant increases of pain threshold were interpreted as induced analgesia and occurred mainly in 5 areas of the trunk, but not in the head or extremities. Analgesic efficacy varied between sexes and among 3 groups of points chosen fro...
Bowman KF, Leitch M, Nunamaker DM, Fackelman GE, Tate LP, Park MI, Boles CL, Raker CW.A total of 19 Thoroughbred horses were treated for traumatic disruption of the suspensory apparatus, using either external support of the injured limb, removal of fractured proximal sesamoid bone fragments, metacarpophalangeal arthrodesis, compression screw fixation of the fractured proximal sesamoid bones, application of a cast-brace attached to a transfixation pin inserted through the third metacarpal bone, or combinations thereof. Major complications during the treatment of traumatic disruption of the suspensory apparatus were infection (9 of 19 horses, 47%), large cast sores (10 of 14 trea...
Morgan RF, Nichter LS, Friedman HI, McCue FC.Three men with thumb injuries sustained during rodeo roping competition have been treated recently. Two of the thumbs were amputated, and the third was partially avulsed. The mechanism of injury was identical in all three cases. The thumbs were entwined between the rope and saddle horn while reducing the slack in the rope and then subjected to shearing and crushing forces as tension was placed on the rope. These injuries emphasize the importance of keeping the thumb upward and clear of the rope to avoid entrapment between the rope and saddle horn.
Kaneps AJ, Hultgren BD, Riebold TW, Shires GM.Surgical incisions were made in the skin and superficial digital flexor tendons in horses. A low intensity laser therapy device was used to treat the limbs. After laser therapy was completed, skin and superficial digital flexor tendons from incised laser-irradiated, incised-control, and nonincised-control limbs were compared microscopically. Qualitative differences between laser irradiated and nonirradiated tissues were not found. The laser therapy device used in this study may be of insufficient power to affect wound healing.
McKibbin LS, Paraschak D.The final and last-quarter race times and racing classes for a group of Standardbreds were analyzed before and after infrared laser light treatment. These horses had either check ligament injuries, plantar desmitis or pharyngeal lymphoid hyperplasia. A 904-nm infrared laser was used to treat check ligaments at 146 Hz for 26 sec/cm2 of affected area, acute plantar desmitis at 73 Hz and chronic plantar desmitis at 292 Hz for 26 sec/cm2 of affected area, and pharyngeal lymphoid hyperplasia at 146 Hz for 5 minutes. Of 35 horses treated for check ligament injuries, 80% had similar or faster final r...
Geiser DR, Walker RD.The pathophysiology and histopathology of thermal burns in large animals is very similar to that in humans. Burns are classified as first degree, superficial and deep second degree, third degree, and fourth degree, depending upon the depth of thermal injury. Most severe burns will produce a local and a systemic response--both of which must be properly treated to increase the patient's chances for survival. The systemic response is mainly characterized by hypovolemia, fluid and electrolyte loss, protein loss, pulmonary edema, increased caloric requirements, and depressed immune responses. The l...
Held JP, Oliver JW.A study was designed to assess the secretory response of thyroid glands in horses to an economically feasible dose (5 IU) of thyrotropin injected IV, and to establish valid blood sampling periods in cases in which thyroxine concentrations were different from base-line values. Significant (P less than 0.001) response (doubling or near-doubling of base line) occurred as early as 3 hours after thyrotropin administration, with peak response at 4 to 5 hours. It was concluded that administration of 5 IU of thyrotropin is economical and effective in the horse, with collection of a second blood sample...
Turner AS, White N, Ismay J.Thirty-five horses with a history of crib biting or wind sucking were treated with a modification of the Forssell procedure. The technique involved bilateral neurectomy of the ventral branch of the accessory nerve combined with excision of a portion of the omohyoideus, sternohyoideus, and sternothyroideus muscles. Twenty horses became free of the vice, while in 11 there was a noticeable reduction in frequency of the vice. Four horses returned to crib biting/wind sucking at the same intensity as before surgery. The observation time following each operation was at least 12 months. Complications ...
Holt PE, Pearson H.The presenting signs, treatment and postoperative progress of 13 horses with vesical and urethral calculi are reviewed. Single, discrete stones were present in 10 animals in which the results of treatment were generally good. In three horses with sabulous cystic deposits, urolithiasis was associated with bladder paralysis and the response to treatment was poor.
Schatzmann U, Girard P.The paper describes the problems of injection anaesthesia in the horse. Different commonly used methods, drugs and drug combinations are explained. Their actions and side-effects are compared and discussed.
Drudge JH, Lyons ET, Tolliver SC.Critical tests were completed on six horses to evaluate the antiparasitic activity of a paste formulation mixture of morantel citrate and trichlorfon, administered intraorally at the dose rate of 6 mg morantel base kg-1 and trichlorfon at 30 mg kg-1. Aggregate average removals were: 78% for two horses infected with 2nd instar Gasterophilus intestinalis; 100% for one infected with 2nd instar G. nasalis; 96% for six infected with 3rd instar G. intestinalis; 100% for four infected with 3rd instar G. nasalis; 100% for five infected with Parascaris equorum; 100% for one infected with mature Oxyuris...
Rutgers LJ, Merkens HW.The half-closed method of castration involves ligation of the spermatic cord enclosed in the vaginal tunic, the testicle itself lying outside the opened vaginal tunic. Of 497 horses and ponies admitted to the Department of Large Animal Surgery and castrated using this technique, 68.6 per cent recovered without complications. Although the most serious postoperative complications such as intestinal eventration and haemorrhage of the spermatic cord may be reduced to a minimum by this approach, normal healing cannot be guaranteed under the circumstances in which this method was used.
Science (New York, N.Y.)August 26, 1983
Volume 221, Issue 4613 823-828 doi: 10.1126/science.6308762
Campbell WC, Fisher MH, Stapley EO, Albers-Schönberg G, Jacob TA.Ivermectin is the 22,23-dihydro derivative of avermectin B1, a macrocyclic lactone produced by an actinomycete, Streptomyces avermitilis. It is active at extremely low dosage against a wide variety of nematode and arthropod parasites, apparently by virtue of its action on the mediation of neurotransmission by gamma-aminobutyric acid. It is now in commercial use in various countries for the treatment and control of parasites in cattle, horses, and sheep, and is expected to become available for use in swine and dogs. Since studies with the drug in man are in a preliminary stage, it is not yet kn...
Shideler RK, Voss JL, Aufderheide WM, Hessemann CP, Squires EL.Twenty mares were assigned to 1 of 4 groups: no altrenogest; altrenogest at 0.044 mg/kg BW; altrenogest at 0.132 mg/kg BW; or altrenogest at 0.220 mg/kg BW. Treatment was administered daily for 86 days. No signs of illness attributable to feeding altrenogest were observed during the trial. Treatment had no effect (P greater than .05) on the following parameters: WBC, differential WBC, platelet number, creatinine, LDH, CPK, total bilirubin, cholesterol, globulin, BSP, and erythrocyte sedimentation rate. When comparing values over time with pretreatment means or among treatment groups, there wer...
Spurlock GH, Gabel AA.One-hundred and nine apical fractures of the proximal sesamoid bones were diagnosed in Standardbred racehorses at the Ohio State University Veterinary Hospital during a 5-year period ending December 1978. Lateral sesamoids of the hindlimbs accounted for 61 of the 109 fractures, which was a significantly (P less than 0.05) greater proportion than that for fractures in all other sesamoid bones. Two- and three-year-old horses accounted for 73 of the 109 apical sesamoid fractures. The remaining 36 apical sesamoid fractures were in horses 4 to 9 years old. The apical fragment was removed in 80 of t...
Peyton LC, Connelly MB.Bacterial quantification was evaluated in 15 cases as a means of wound assessment. This study suggests that bacterial quantification may be used as an aid in the evaluation of treatment procedures and wound preparation in veterinary surgery.
Dik KJ, Nemeth F.Six cases of patella fractures are reported. Three horses presented an avulsion fracture of the medial patellar angle. For a precise diagnosis of this fracture a radiographic skyline view was indispensable; lateral views were not diagnostic. One of these horses recovered after three months' rest but radiographically the fracture remained visible. One horse with a comminuted fracture recovered after five months' rest. A case with a contaminated longitudinal patella fracture was destroyed. The sixth horse had a chip fracture of the dorsomedial part of the patella. The outcome of this case is unk...
Tulamo RM, Bramlage LR, Gabel AA.The case histories and follow-up data for 11 horses with slab fractures of the central or 3rd tarsal bones were examined for information pertaining to the diagnosis, which was difficult to identify, treatment, which was proven ineffective, and the prognosis, which was shown to be poor for return to racing. The purpose of the study was to define the results that could be obtained by nonoperative methods, in an attempt to determine whether surgical treatment was advisable. Nine of the horses were Standardbreds and 2 were Thoroughbreds; all horses were 2 to 4 years old and were being exercised at...
Davies JV, Gerring EL.The effect of acepromazine, Buscopan (Crown Chemicals), pethidine and methadone was evaluated in ponies prepared with Thiry-Vella (T-V) loops. Motility was assessed by electrophysiological means (bipolar electrodes and strain gauge transducers) and by the passage through the T-V loop of a fluid test meal. Results were obtained from 26 experiments in three ponies and compared with six control experiments, in which saline had been administered to the same ponies. Each pony acted as its own control in each experiment and pre and post treatment values for slow wave frequency, spiking activity, del...
Threlfall WR, Keefe TJ.Serum levels of ticarcillin disodium, a semi-synthetic penicillin (Beecham Laboratories, Bristol, Tennessee, 37620), were measured at various time intervals up to and including 24 h after intrauterine and intramuscular administration in adult female horses. Three separate studies were conducted in Part I: in the first and second studies, serum levels were measured after intrauterine administration of 1 and 3 g of ticarcillin, respectively, and in the third study, levels were measured after intramuscular administration of 6 g of ticarcillin. In Part II, serum levels of ticarcillin were measured...
Ducharme NG, Fubini SL.Atropine sulfate was given at 2 dosages (0.044 mg/kg, 0.176 mg/kg) to clinically normal ponies in order to evaluate the drug's effect on the gastrointestinal tract. Intestinal motility, as assessed by ausculation of borborygmus, was stopped 30 minutes after injection, but it gradually returned to normal within 12 hours. Signs of abdominal pain developed in 3 of 10 ponies. In 3 clinical cases of gastrointestinal disorder, prior atropine treatment was confusing to the diagnostician and resulted in delayed surgical treatment in 1 case. It was concluded that atropine should not be used for allevia...
Giusto G, Gandini M.The return to performance after colic surgery is crucial for competition horses. While studies have investigated racehorse performance following colic surgery by analysing racing participation and earnings, this approach does not apply to showjumping horses, leaving a gap in the literature regarding their objective performance evaluation. Objective: To assess the short- and long-term survival and return to performance in showjumping horses after colic surgery. Methods: Retrospective case series. Methods: Medical records of horses with acute colic requiring surgical treatment were analysed, and...
Botelho JHV, Pessoa GO, Caixeta ES, Sales G, de Oliveira KR, Nascimento Neto JDP, Ferreira RD, Palhão MP.This study aimed to evaluate the localised effects of intrauterine ozone therapy on endometrial recovery in mares with endometritis. Our investigation assessed changes in gene expression profiles of anti-inflammatory (IL-1RA and IL-10), proinflammatory (IL-R1B3i and TNFα) and pleiotropic (IL-6) cytokines, along with detailed histological measurements of epithelial and endometrial thickness and the glandular area ratio. Twenty mares were assigned to a 2 × 2 factorial design based on endometritis diagnosis and treatment (control or 42 μg/mL ozone insufflation), resulting in four groups: N...
Rudnick MJ, Stewart HL, Burleson MD, Levine DG.Slow hoof growth poses a clinical challenge when hoof wear exceeds natural growth. Many treatment options have been reported without controlled prospective trials. The objective of this study was to evaluate the effect of transdermal CO2 on the rate of growth in treated hooves. Methods: A prospective, randomized, blinded, crossover study of 14 Warmblood mares. Horses were randomly assigned a number and allocated for treatment of the front feet with room air or CO2 for 30 minutes 3 times per week, and groups were switched after 5 weeks. Hoof growth was measured on the dorsal midline and the qua...
Long AE, Hurcombe S, Hopster K.To compare the ability of bioreactance noninvasive cardiac output (BR-NICO) with thermodilution cardiac output (TDCO) for the measurement of cardiac output (CO) in healthy adult horses receiving 2 different IV volume replacement solutions. Methods: Prospective randomized crossover study from September to November 2021. Methods: University teaching hospital. Methods: Six university-owned adult horses. Methods: Horses were randomly assigned to receive 7.2% hypertonic saline solution (HSS) or 6% hydroxyethyl starch (130/0.4) solution (HETA). BR-NICO and TDCO were measured simultaneously at baseli...
Américo L, Aquino LPCT, Moura AB, Ribeiro GSN, Fonteque JH, Chryssafidis AL.Habronemosis, also known as habronemiasis or habronematidosis, is a parasitic disease of equids caused by the larval stages of Habronematidae nematodes (Habronema muscae, Habronema microstoma, and Draschia megastoma) that are transmitted by muscid flies. The presence of aberrant infective larvae in the cutaneous and conjunctival tissues of these hosts results in granulomatous, exudative, and ulcerated lesions, also known as "summer sores." In this study, we present a retrospective analysis of habronemosis cases in horses from the municipality of Lages, located on the Santa Catarina Plateau, a ...
Franzen V, Gruber NA, Klußmann S, Schoster A, May A.Trigeminal-mediated headshaking is a neuropathic facial pain condition in horses. No treatment has been entirely successful. Repetitive transcranial magnetic stimulation (rTMS) is used in human medicine as a treatment for various neuropathic pain conditions, and good results have been achieved in cases of trigeminal neuralgia. Objective: Apply rTMS to horses with trigeminal-mediated headshaking (TMHS) and to evaluate tolerability, application of the setting, and success rate. Methods: Seventeen horses with nonseasonal signs of TMHS. Methods: Other underlying causes of headshaking were ruled ou...
Samuels A, Burns TA.Lymphoma and myeloproliferative diseases in horses are relatively uncommon. The clinical signs, prognosis, and treatment options depend upon the anatomic location and subtype. Significant gaps in knowledge remain regarding prevalence, pathogenesis of different subtypes, antemortem diagnostic tests, response to treatment, and standardized treatment protocols. However, treatment options are available, accessible on the farm, and could improve quality of life and prolong survival.
Bulnes F, Argüelles D, Buzón A, García-Álamo K, Rodríguez-Gómez IM, Hernández E, Mozos E.This case report details a long-term follow-up of a hoof melanoma with dermo-epidermal activity (resembling Spreading Superficial Melanoma (SSM)) in a bay horse with a history of a right front hoof keratoma. Melanomas involving the horse's foot are seldom reported and usually diagnosed as anaplastic melanomas based on signalment and post-mortem examination. The clinical-pathological characteristics of the foot melanoma in this bay horse are consistent with SSM-like described in humans, which is considered an intermediate malignant tumour attending their biological behaviour. However, a definit...
Monteiro LC, Costa CM, Ermita PAN, Júnior SJPG, Mattos FS, Mansur FC, Dos Santos MO, Alves SR, Mafort EG, Fidélis CF, Avanza MFB, Teixeira RBC....In adult horses, the development and evaluation of enteral electrolyte solutions containing sodium acetate for correcting hyperchloremic metabolic acidosis are still lacking, although these electrolyte and acid-base imbalances are commonly observed. The objective of this study was to evaluate the alkalinizing effect of two enteral electrolyte solutions containing different concentrations of acetate, administered via nasogastric tube in continuous flow, in adult horses with experimental hyperchloremic metabolic acidosis. Unassigned: Six mares aged between 3 and 10 years were used in a 6×2 cr...
Derbala MK, Abu-Seida AM, El-Metwally AE, Asfour HAE.Embryo transfer (ET) is regarded as one of the reproductive methods for genetic improvement initiatives in the horse business. The current study aimed to increase the success rate of ET by re-flushing and re-transferring of embryos from contaminated recipient mares into second healthy recipients. The study involved 25 recipient mares that demonstrated embryonic vesicles inside intraluminal fluid (ILF) on ultrasound scanning 2 ± 0.5 days after ET. Seven recipient mares were left without re-flushing and re-transferring of embryos (control group) and 18 recipient mares (treated group) were subje...
Malsa J, Reigner F, Riou M, Gesbert A, Guégnard F, Perrot N, Serreau D, Fleurance G, Sallé G.The increasing emergence of anthelmintic-resistant parasitic isolates prompts us to reassess the management of intestinal strongylosis in horses. Additionally, societal demand is shifting toward reducing the use of chemical treatments, aligning with environmentally-friendly practices and the exploration of natural alternatives. In this context, we provide an initial view of the antiparasitic activity and the effect on immune circulating blood cells of three commercialized plant-based feed additives in ponies. Three treatments, based either on mugwort (Artemisia vulgaris), echinacea (Echinacea ...
Cassiers V, McNally T.Palatal dysfunction (PD), which encompasses palatal instability (PI) and intermittent dorsal displacement of the soft palate, is the most common performance-limiting upper respiratory tract obstruction in young Thoroughbred racehorses. Soft palate thermocautery (SPT) performed under general anaesthesia is a routinely performed procedure for PD in some countries, but the procedure for and outcome of SPT performed under standing sedation has not been published. (1) To describe a technique for SPT performed under standing sedation; and (2) to assess post-operative performance in horses compared t...
de Melo UP, Ferreira C.This report describes five cases of urinary incontinence in Quarter Horse mares associated with the development of sabulous cystitis. The animals in this study had a history of persistent urinary incontinence for eight months, with clinical signs of continuous dribbling urine during rest and movement. The initial treatment with antibiotics and anti-inflammatory drugs was ineffective. Clinical examination revealed severe scalding in the perineal region and on the medial aspect of the hind limbs, along with neurological signs such as ataxia, hind limb paresis, and diminished perineal reflexes. T...
Smith HL, Love KR, Antezana A, Barr EM, Gilger BC, Oh A.To determine clinical outcome, treatment costs, and hospitalization duration in horses treated for keratomycosis and identify ophthalmic examination and diagnostic results associated with these outcomes. Methods: This was a retrospective study of 126 equine keratomycosis cases between 2004 and 2020 with fungal infection confirmed on cytology, culture, and/or histopathology and a minimum of 1-month follow-up. Details of the ophthalmic examination, diagnostic test results, and treatment and cost outcomes were recorded. Outcomes of interest were analyzed by treatment type. The relationship of pat...
Kuroda T, Minamijima Y, Kinman CK, Takahashi Y, Ebisuda Y, Inoue K, Ishikawa H, Mita H, Tamura N, Nukada T, Toutain PL, Ohta M.Quinidine (QND) sulfate is an effective treatment for atrial fibrillation (AF) in horses, and several dosage regimens have been proposed to address its wide variability in response and potential adverse effects. The purpose of this study was to analyze the variability in plasma quinidine concentrations using population pharmacokinetics to determine an effective and safe dosage regimen for Thoroughbred horses. Unassigned: Six healthy Thoroughbred horses were treated with 20 mg/kg quinidine sulfate dihydrate (16.58 mg/kg QND base) administered PO or 5 mg/kg quinidine hydrochloride monohydr...
Apolonio EVP, Gobbo LL, Woiblet NG, Dinau FC, Pyles MS, Ferrari LC, de Moura Alonso J, Alves ALG.Vascular hamartoma is an abnormal development of endothelial tissue that rarely affects horses. Histopathological examination remains the gold standard for definitive diagnosis, yet the presence of abnormal vascular structures must be carefully differentiated from other vascular anomalies and neoplasms. This report describes two cases of vascular proliferation affecting the skin on the lateral side over the left tarsus and the dorsolateral region over the fetlock joint of two fillies. The clinical history, presentation, and radiographic and sonographic findings in both patients suggested a neo...
Kwak YB, Seo SA, Kim M, Yoon J.Ethyl pyruvate (EP) has emerged as a promising compound with potential therapeutic benefits attributed to its anti-inflammatory and antioxidant properties. This study aimed to understand the effects of EP on plasma metabolites and immune cells in horses, utilizing advanced liquid chromatography-mass spectrometry (LC-MS)-based metabolomics, quantitative polymerase chain reaction (qPCR), and blood chemistry analyses. Our comprehensive analysis detected 2,366 ions, and 126 metabolites were accurately identified. Remarkably, EP administration induced significant changes in 28 metabolites at 1 h a...
Sousa LN, Winter IC, Varela DD, Luvison EZ, Guzmán JFC, Machado AMV, Figueiredo RDV, Pena GT, Dos Santos ACS, Faleiros RR, Carvalho AM.The present study involved seven horses in a randomized crossover clinical trial to evaluate the effect of lidocaine on horses with induced endotoxemia. Horses received intravenous lidocaine (1.5 mg/kg bolus, followed by 0.05 mg/kg bwt/min) or placebo (0.9% sodium chloride at the same manner) one hour before LPS administration (0.03 μg/kg, IV infusion over 30 min). We monitored clinic and hematologic parameters, abdominal auscultation, ultrasound, and pain over time. No relevant clinical differences existed between treatments regarding peristalsis, abdominal pain, or any other parameters befo...
de Moura Alonso J, Watanabe MJ, de Moraes Gimenes Bosco S, Apolonio EVP, de Vasconcelos AB, do Prado AC, Alves ALG, Rodrigues CA, Hussni CA.Fungal rhinitis in horses is rare, although severe, due to the progressive nasal obstruction. Aspergillus is one of the fungi most often involved in these cases. A 7-year-old Quarter Horse mare weighing 325 kg was admitted with a history of recurrent nasal discharge and bleeding, foul smell, reluctance to exercise, and abortion. Laboratory and imaging examinations revealed eosinophilia, scarring and erosion areas in the nasal mucosa, purulent and bloody secretions, and remarkable yellowish plaques. Histopathological examination revealed fungal rhinitis and bacterial culture revealed the prese...
Charles A, Peeters X, Verbrugghe C, Vandersmissen M, Evrard L, Busoni V.The Pivot Point (PP) method is commonly used in the radiographic assessment of carpal deformities in young foals, as the range of deviation may influence treatment choice. The aims of this study were to assess the intra- and interobserver reproducibility of the PP method and subjective radiographic evaluation without line drawing to establish the anatomical site responsible for carpal deviation in foals and to evaluate the agreement between these two techniques. Unassigned: Anonymized radiographs of foals presented for investigation of carpal deformity or prematurity were retrospectively and i...
Gomez DE, Kopper JJ, Byrne DP, Renaud DL, Schoster A, Dunkel B, Arroyo LG, Mykkanen A, Gilsenan WF, Pihl TH, Lopez-Navarro G, Tennent-Brown BS....This study aimed to describe and compare therapeutic approaches for horses with acute diarrhea in different geographic regions worldwide. Methods: Clinical information was retrospectively collected from diarrheic horses presented to participating institutions between 2016 and 2020, including fluid therapy on admission, antimicrobial drugs, probiotics, anti-endotoxic medications, anti-inflammatory drugs, gastroprotectants, digital cryotherapy, and toxin-binding agents. Seasonal and geographic differences were investigated. Results: 1438 horses from 26 participating hospitals from 5 continents w...
Julia M, Felippe B.The clinical manifestation of recurrent fevers and infections alerts the clinician to the possibility of an underlying immunodeficiency. Common variable immunodeficiency (CVID) in the horse is a rare late-onset, non-familial immunologic disorder of B cell depletion and/or dysfunction with resultant inadequate antibody production. The most common clinical presentations in horses with CVID are recurrent upper and/or lower respiratory infections, meningitis and/or ataxia, cholangiohepatitis, infectious colitis, infectious dermatitis, and severe gastrointestinal parasitism. Immune-mediated and lym...
Sidwell AE, Duz M, Khan A, Bodnàr R, Hole SL.The translocation of gingival commensals resulting in measurable systemic inflammation has been described in humans and non-equine veterinary species with dental disorders, particularly periodontal disease. Routine odontoplasty does not result in increased serum amyloid A (SAA) concentration in horses, but a measurable increase in SAA concentration in horses undergoing dental extractions could suggest that local inflammation resulting from more severe dental disease has potential for wider, systemic consequences that warrants further study. To determine whether SAA increases in horses undergoi...
Guest DJ, Birch HL, Thorpe CT.The suspensory ligament (SL) is a key component of the elaborate and highly adapted suspensory apparatus in the horse. In addition to contributing to stabilisation of the metacarpophalangeal joint, the SL has a spring like function to reduce the energetic cost of locomotion. Although the SL is highly prone to injury in horses of all ages and competing in a wide range of disciplines, knowledge regarding fundamental structure-function relationships in the SL is lacking, particularly compared with other injury-prone tendinous structures such as the superficial digital flexor tendon. In this revie...
Resende AM, Miranda BA, Silva LB, Oliveira AB, Castro MB, Macêdo IL, Dallago BSL, Barud HS, Borges MAC, Ribeiro CA, Dias DS, Campebell RC.Background/Objectives: Skin injuries are common in the equine clinical practice, requiring effective treatment to support natural healing. Bacuri butter is gaining attention for its potential in wound healing and its anti-inflammatory, antimicrobial, and antioxidant properties. Natural polymers such as onion (Allium cepa) bioplastics have been investigated for their potential as occlusive dressings and for tissue regeneration. Methods: This study evaluated the healing process of experimentally induced skin wounds on horses treated with bacuri butter, washed onion film, and unwashed onion film....
Lensing R, Wirth C, Thünker F, Merle R, Barton AK.Gastric pH is a key factor in the development of equine squamous gastric disease (ESGD). Although acid injury is unlikely the primary cause of equine glandular gastric disease (EGGD), low pH may promote mucosal damage. Gastric pH is influenced by roughage uptake, as chewing increases the alkaline saliva production. The proton pump inhibitor omeprazole is currently recommended by the American/European College of Veterinary/Equine Internal Medicine (ACVIM/ECEIM) for ESGD and EGGD. We hypothesized that dental disorders decrease saliva production and gastric pH, predisposing horses to EGUS. Gastro...
Willette JA, Tsoi M, Frobish D, VanderBroek AR.The objectives of the study were to describe a standing percutaneous adhesion induction model in the digital flexor tendon sheath (DFTS) of horses and to evaluate the effect of intrathecal administration of the angiotensin-converting enzyme (ACE) inhibitor enalapril on tendon healing and adhesion formation. Methods: Randomized, blinded, controlled experimental study. Methods: Eight healthy horses. Methods: A collagenase-induced adhesion model was implemented in the deep digital flexor tendon (DDFT) of both forelimbs under standing ultrasonographic guidance. Daily intrathecal injections of 5 ...
Witt P, Stas EKL, Hardeman LC, van Proosdij ER, Weerts EAWS, Lloyd-Edwards RA, Veraa S, Kranenburg LC, van den Boom R.A sixteen-year-old Friesian mare was admitted to the university clinic with the following clinical signs: anorexia, weight loss, fever, bilateral nasal discharge, unilateral facial paralysis and a non-healing corneal lesion. Endoscopic examination of the upper airways showed thickening of the proximal portion of the right stylohyoid bone. Computed tomography imaging showed pneumocephalus due to grade 3 unilateral temporohyoid osteoarthropathy (THO) with fracture of the petrous temporal bone. The horse did not improve following medical treatment. Surgical intervention was declined by the owner ...
Rodrigues LT, Segabinazzi L, Frasson M, Dell'Aqua C, Carmo MT, Takahira RK, Alvarenga M, Papa F.Although protocols for superovulation have been described in horses, this technique has been discouraged due to the low embryo recovery rates in superovulated mares. The reason for these poor results is poorly understood, but the formation of a blood clot in the ovulation fossa following ovulations has been hypothesized. Therefore, this study aimed to assess the safety and effect of periovulatory anticoagulant therapy on embryo recovery of superovulated mares. In experiment 1, five mares were assigned to receive five anticoagulant treatments in a crossover design: intravenous injections of 150...
Varner KM, Curtiss AL, Hogan PM, Love K, Dodam JR.In anaesthetised horses, bradycardia secondary to high vagal tone can reduce cardiac output and blood pressure. The use of anticholinergics in horses is limited due to concerns about ileus and abdominal discomfort. This retrospective study sought to determine the prevalence of post-operative abdominal discomfort in healthy horses that received atropine under isoflurane anaesthesia. Methods: A retrospective evaluation of 222 general anaesthesia events between January 2019 and December 2019 was undertaken. Methods: One hundred and eleven horses that received atropine were identified, and 111 cas...
