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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Pulmonary function and antimicrobial concentration after marbofloxacin inhalation in horses.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 348-350 doi: 10.1136/vr.161.10.348
Art T, de Moffarts B, Bedoret D, van Erck E, Lekeux P.No abstract available
Evaluation of serum amyloid A and surfactant protein D in sera for identification of the clinical condition of horses with bacterial pneumonia.
The Journal of veterinary medical science    September 11, 2007   Volume 69, Issue 8 827-830 doi: 10.1292/jvms.69.827
Hobo S, Niwa H, Anzai T.In the present study, the concentrations of serum amyloid A and surfactant protein D in sera were measured to evaluate them for identification of the clinical condition of horses with bacterial pneumonia. The study utilized 185 clinically healthy control thoroughbreds and 9 thoroughbreds for experimental infectious study with S. zooepidemicus. Blood samples were collected from the 185 healthy control thoroughbreds. The 9 thoroughbreds were experimentally infected S. zooepidemicus using an endoscopic injection to a lung lobe and were then observed of clinical conditions. Blood samples were coll...
Use of matrix metalloproteinases 2 and 9 and white blood cell counts in monitoring the treatment and predicting the survival of horses with septic arthritis.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 329-334 doi: 10.1136/vr.161.10.329
Kidd JA, Barr AR, Tarlton JF.Thirty-nine samples of synovial fluid were collected from the joints of 32 horses with suspected septic arthritis and 39 samples were collected from horses euthanased for non-orthopaedic conditions. The white blood cell counts (WBCC) were determined and the pro and active forms of matrix metalloproteinases (MMPs) 2 and 9 were measured by gelatin zymography and image analysis in each sample. The initial measurements of the ratio of proMMP9:proMMp2 and WBCC were good prognostic indicators of the survival of the horses. There was no significant relationship between the interval between the injury...
MRSA infection in horses.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 359-360 doi: 10.1136/vr.161.10.359-a
Weese JS.No abstract available
Detection of antibodies to equine arteritis virus in horse sera using recombinant chimaeric N/G(L) protein.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 352-354 doi: 10.1136/vr.161.10.352
Turan N, Ekici H, Yilmaz H, Kondo T, Hasoksuz M, Sato I, Tuchiya K, Fukunaga Y.No abstract available
How long will equestrian traditionalism resist science?
Veterinary journal (London, England : 1997)    September 11, 2007   Volume 175, Issue 3 289-290 doi: 10.1016/j.tvjl.2007.06.017
van Weeren PR.No abstract available
Removal of a sialolith by an intraoral surgical approach in a warmblood gelding.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 354-356 doi: 10.1136/vr.161.10.354
Haralambus RM, Simhofer H, Zappe H.No abstract available
Morphologic changes associated with functional adaptation of the navicular bone of horses.
Journal of anatomy    September 11, 2007   Volume 211, Issue 5 662-672 doi: 10.1111/j.1469-7580.2007.00800.x
Bentley VA, Sample SJ, Livesey MA, Scollay MC, Radtke CL, Frank JD, Kalscheur VL, Muir P.Failure of functional adaptation to protect the skeleton from damage is common and is often associated with targeted remodeling of bone microdamage. Horses provide a suitable model for studying loading-related skeletal disease because horses are physically active, their exercise is usually regulated, and adaptive failure of various skeletal sites is common. We performed a histologic study of the navicular bone of three groups of horses: (1) young racing Thoroughbreds (n = 10); (2) young unshod ponies (n = 10); and (3) older horses with navicular syndrome (n = 6). Navicular syndrome is a painfu...
Detection of an isoform of alpha(1)-antitrypsin in serum samples from foals with gastric ulcers.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 338-342 doi: 10.1136/vr.161.10.338
Taharaguchi S, Nagano A, Okai K, Miyasho T, Kuwano M, Taniyama H, Yokota H.The objective of this study was to find serum indicators of gastric ulcers in foals. By using two-dimensional electrophoresis of serum proteins, three distinct spots were detected in samples from foals with gastric ulcers detected endoscopically. One of them appeared with high frequency and was identified by partial digestion with trypsin and subsequent nano-electrospray ionisation-tandem mass spectrometry (nanoesi-ms/ms) analysis as an alpha(1)-antitrypsin. Western blot analysis, using an antibody against human alpha(1)-antitrypsin, revealed at least two bands, of molecular weight 58 kDa and ...
Molecular diagnosis of certain nematode infections can save life and beauty, and preserve breeds of socially relevant and sporting animals.
Veterinary parasitology    September 11, 2007   Volume 150, Issue 1-2 1-5 doi: 10.1016/j.vetpar.2007.08.011
Traversa D.The recognition that the health and welfare of some humans are improved through contact and relationships with animals is now established. Two commonly recognized assistance animals are dogs and horses. Both provide therapeutic benefits to humans with some physical and mental illnesses and both assist people with disabilities. Moreover, the public and scientific attention to the health and conservation of many animal breeds is also increasing worldwide. In the past few years, two potentially life-threatening nematode infections that can induce tumours or tumour-like masses in canids and equids...
Abortion in a thoroughbred mare associated with an infection with avirulent Rhodococcus equi.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 342-346 doi: 10.1136/vr.161.10.342
Nakamura Y, Nishi H, Katayama Y, Niwa H, Matsumura T, Anzai T, Ohtsu Y, Tsukano K, Shimizu N, Takai S.An eight-year-old thoroughbred mare with no previous history of illness aborted a fetus at 196 days of gestation, and its internal tissues were examined immunohistologically and bacteriologically. The placenta was not examined, but specimens of the intrauterine fluids and the dam's faeces were collected four days after the abortion and examined bacteriologically. No significant histological lesions were found in the fetus but the amnion and the umbilical cord were oedematous and had petechial haemorrhages. Rhodococcus equi was isolated in pure culture from the lung, heart and stomach contents ...
Factors concerning early embryonic death in thoroughbred mares in South Korea.
The Journal of veterinary medical science    September 11, 2007   Volume 69, Issue 8 787-792 doi: 10.1292/jvms.69.787
Yang YJ, Cho GJ.A total of 384 Thoroughbred mares were investigated to determine and evaluate the features of early embryonic death at nine equine farms on Jeju Island, South Korea, from 2001 to 2003. Overall, 771 matings for 384 mares resulted in 376 pregnancies 15 days after ovulation. Subsequently, 12.2% (46/376) of these early conceptuses were lost within 45 days after ovulation. Furthermore, about three quarters of the 46 embryonic deaths occurred between 16 and 25 days after ovulation. The incidence of embryonic death was highest in the barren (17.2%), more than 15 years old (15.4%), and more than 10 pa...
Glossitis and tongue trauma subsequent to administration of an oral medication, using an udder infusion cannula, in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    September 11, 2007   Volume 48, Issue 8 845-847 
Fuller MC, Abutarbush SM.A 10-year-old gelding was presented with a tongue that had swelled immediately after oral administration of oxfendazole, using an udder infusion cannula. The tongue appeared to have been punctured inadvertently. The horse recovered after treatment with intravenous fluid, antibiotics, and anti-inflammatory drugs. Administering oral medication by this method should be discouraged. Un cheval hongre âgé de 10 ans a été présenté avec une langue devenue tuméfiée immédiatement après l’administration orale d’oxfendazole à l’aide d’une canule à infusion du pis. La langue semblait a...
Atypical myopathy in two grazing horses in northern Spain.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 346-348 doi: 10.1136/vr.161.10.346
Palencia P, Rivero JL.No abstract available
Repair of a Salter-Harris type II fracture of the calcaneus of a foal.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 350-352 doi: 10.1136/vr.161.10.350
Boado A, Clutton E, Booth TM.No abstract available
Pharmacokinetics of acyclovir after intravenous infusion of acyclovir and after oral administration of acyclovir and its prodrug valacyclovir in healthy adult horses.
Antimicrobial agents and chemotherapy    September 10, 2007   Volume 51, Issue 12 4308-4314 doi: 10.1128/AAC.00116-07
Garré B, Shebany K, Gryspeerdt A, Baert K, van der Meulen K, Nauwynck H, Deprez P, De Backer P, Croubels S.The purpose of this study was twofold. The first aim was to evaluate the oral bioavailability and pharmacokinetics (PKs) of acyclovir in horses after intravenous (i.v.) administration and after oral administration of acyclovir and its prodrug, valacyclovir. Second, we aimed to combine these PK data with pharmacodynamic (PD) information, i.e., 50% effective concentrations (EC(50) values) from in vitro studies, to design an optimal dosage schedule. Three treatments were administered to healthy adult horses: 10 mg of acyclovir/kg of body weight delivered as an i.v. infusion over 1 h, 20 mg of acy...
Evaluation of the in vivo behaviour of gentamicin sulphate ocular mini-tablets in ponies.
Journal of veterinary pharmacology and therapeutics    September 7, 2007   Volume 30, Issue 5 470-476 doi: 10.1111/j.1365-2885.2007.00890.x
Gasthuys F, Pockelé K, Vervaet C, Weyenberg W, De Prijck K, Pille F, Vlaminck L, Nelis H, Remon JP.The in vivo behaviour of 5% gentamicin sulphate ocular mini-tablets (2-mm diameter, 6.525 mg weight) was compared with gentamicin eye drops in six ponies. Two mini-tablets were inserted on the bulbar conjunctiva of the right eye while a similar dose of gentamicin was administered via eye drops in the left eye. Irritation induced by the mini-tablets and the eye drops was evaluated using a visual analogue scale (0-10). Tears were sampled with ophthalmologic absorption triangles for 1 min for the determination of the concentration of gentamicin sulphate using a microbiological plate diffusion met...
Equine recurrent airway obstruction does not alter airway muscarinic acetylcholine receptor expression and subtype distribution.
Journal of veterinary pharmacology and therapeutics    September 7, 2007   Volume 30, Issue 5 401-409 doi: 10.1111/j.1365-2885.2007.00897.x
Abraham G, Kottke C, Ungemach FR.In recurrent airway obstruction (RAO) or heaves, bronchospasm has been attributed to enhanced cholinergic activity. However, the expression and function of muscarinic acetylcholine receptors (mAChR) and their signaling components are not yet known. Thus, we examined the expression, subtype distribution and postreceptor signaling pathways of mAChR in the peripheral lung, bronchial and tracheal epithelia with the underlying smooth muscle from nine horses with RAO and 11 healthy control horses. In RAO horses, no significant segment-dependent alteration in mAChR density and subtype distribution (a...
Some pharmacodynamic effects of eformoterol in the horse.
Journal of veterinary pharmacology and therapeutics    September 7, 2007   Volume 30, Issue 5 496-499 doi: 10.1111/j.1365-2885.2007.00882.x
Ladaga GJ, Lezica FP, Ferraro G, De Erausquin GA.No abstract available
Pelger-Huët anomaly in an Arabian horse.
Veterinary clinical pathology    September 7, 2007   Volume 36, Issue 3 306-310 doi: 10.1111/j.1939-165x.2007.tb00231.x
Grondin TM, DeWitt SF, Keeton KS.A 9-year-old Arabian mare was evaluated for a 7-day history of malaise. Results of a CBC included a leukocyte concentration within the reference interval (8.4 x 10(3)/microL, reference interval 6.0-14.0 x 10(3)/microL) with an apparent degenerative left shift (segmented neutrophils 1.2 x 10(3)/microL, reference interval 2.5-7.5 x 10(3)/microL; hyposegmented neutrophils 1.8 x 10(3)/microL, reference interval 0.0-0.2 x 10(3)/microL). Serum clinical chemistry results included increased aspartate transaminase, alkaline phosphatase, and gamma-glutamyltransferase activities. A presumptive diagnosis ...
Risk factors for influenza infection in vaccinated racehorses: lessons from an outbreak in Newmarket, UK in 2003.
Vaccine    September 6, 2007   Volume 25, Issue 43 7520-7529 doi: 10.1016/j.vaccine.2007.08.038
Barquero N, Daly JM, Newton JR.Between March and May 2003, clinical equine influenza was confirmed among vaccinated racehorses in Newmarket, UK. A particular feature was that 2-year-old horses were apparently less susceptible than older animals. Statistical analyses comparing infected and non-infected animals showed the unusual, apparently counter-intuitive inverse age effect was principally explained by more recent vaccination among younger animals, despite broadly equivalent antibody levels between age groups. There was novel evidence for sexual dimorphism in susceptibility to infection and data supported the hypothesis t...
West Nile virus outbreak detection using syndromic monitoring in horses.
Vector borne and zoonotic diseases (Larchmont, N.Y.)    September 5, 2007   Volume 7, Issue 3 403-410 doi: 10.1089/vbz.2006.0593
Leblond A, Hendrikx P, Sabatier P.Recent outbreaks of West Nile virus-associated (WNV) diseases, both in the old World and Americas, underline the importance for early warning systems that rapidly identify emerging and re-emerging diseases and thus help in their control. Traditional approaches of disease monitoring become less reliable and increasingly costly when used for rare health-related events, such as WNV outbreaks in southern France. The objective of this work was to discuss methodological issues related to syndromic monitoring of WNV-associated disease in Camargue horses by veterinary practitioners. Tracking cases of ...
Gabapentin for the treatment of neuropathic pain in a pregnant horse.
Journal of the American Veterinary Medical Association    September 4, 2007   Volume 231, Issue 5 755-758 doi: 10.2460/javma.231.5.755
Davis JL, Posner LP, Elce Y.A 24-year-old 732-kg (1,610-lb) pregnant Belgian draft horse mare developed neuropathy and signs of intractable pain following colic surgery. Results: Following recovery from colic surgery to treat compression of the small and large intestines because of a large fetus, the mare was noticed to have signs of femoral neuropathy involving the left hind limb. Within 36 hours after recovery, the mare developed signs of severe pain that were unresponsive to conventional treatment. No gastrointestinal tract or muscular abnormalities were found, and the discomfort was attributed to neuropathic pain. Re...
What is your diagnosis? Nonneoplastic myelofibrosis of the medullary cavity.
Journal of the American Veterinary Medical Association    September 4, 2007   Volume 231, Issue 5 695-696 doi: 10.2460/javma.231.5.695
Rosser J, Baxter GM.No abstract available
Pharmacologic characterization of novel adenosine A2A receptor agonists in equine neutrophils.
American journal of veterinary research    September 4, 2007   Volume 68, Issue 9 981-987 doi: 10.2460/ajvr.68.9.981
Sun WC, Moore JN, Hurley DJ, Vandenplas ML, Linden JM, Murray TF.To evaluate anti-inflammatory effects of several novel adenosine receptor agonists and to determine their specificity for various adenosine receptor subtypes on neutrophils, cells heterologously expressing equine adenosine receptors, or equine brain membranes. Methods: Neutrophils isolated from 8 healthy horses. Methods: Radioligand binding experiments were performed to compare binding affinities of adenosine receptor agonists to equine adenosine A(1), A(2A), and A(3) receptor subtypes. Effects of these agonists on endotoxin-induced production of reactive oxygen species (ROS) by equine neutrop...
Central vestibular syndrome due to a squamous cell carcinoma in a horse.
The Veterinary record    September 4, 2007   Volume 161, Issue 9 314-316 doi: 10.1136/vr.161.9.314
D'Angelo A, Bertuglia A, Capucchio MT, Riondato F, Zanatta R, Gandini G.No abstract available
Validation of quantitative polymerase chain reaction assays for measuring cytokine expression in equine macrophages.
Journal of immunological methods    September 4, 2007   Volume 328, Issue 1-2 59-69 doi: 10.1016/j.jim.2007.08.006
Allen CA, Payne SL, Harville M, Cohen N, Russell KE.The study of the equine immune system and inflammatory responses, by measuring cytokine expression, can provide important insight into disease pathogenesis in the horse. A set of quantitative real-time polymerase chain reaction (QPCR) assays for the equine cytokines IL-1alpha, IL-1beta, IL-6, IL-8 and TNF-alpha were validated using QPCR primers and probes which were generated for the equine IL-1alpha, IL-1beta, IL-6, IL-8, TNF-alpha and 18S genes. Amplification efficiency, intra-assay and inter-assay variation were determined using 10-fold dilutions of plasmid for each gene. Under these condit...
Effect of fibroblast growth factor-2 on equine mesenchymal stem cell monolayer expansion and chondrogenesis.
American journal of veterinary research    September 4, 2007   Volume 68, Issue 9 941-945 doi: 10.2460/ajvr.68.9.941
Stewart AA, Byron CR, Pondenis H, Stewart MC.To determine whether fibroblast growth factor-2 (FGF-2) treatment of equine mesenchymal stem cells (MSCs) during monolayer expansion enhances subsequent chondrogenesis in a 3-dimensional culture system. Methods: 6 healthy horses, 6 months to 5 years of age. Methods: Bone marrow-derived MSCs were obtained from 6 horses. First-passage MSCs were seeded as monolayers at 10,000 cells/cm(2) and in medium containing 0, 1, 10, or 100 ng of FGF-2/mL. After 6 days, MSCs were transferred to pellet cultures (200,000 cells/pellet) and maintained in chondrogenic medium. Pellets were collected after 15 days....
ECG of the month. Ventricular tachycardia in a horse.
Journal of the American Veterinary Medical Association    September 4, 2007   Volume 231, Issue 5 706-708 doi: 10.2460/javma.231.5.706
Johnson AL, Jesty SA, Gelzer AR, Divers TJ, Kraus MS.No abstract available
Evaluation of a turbidimetric immunoassay for measurement of plasma IgG concentration in foals.
American journal of veterinary research    September 4, 2007   Volume 68, Issue 9 1005-1009 doi: 10.2460/ajvr.68.9.1005
McCue PM.To validate a turbidimetric immunoassay (TIA) for measurement of plasma IgG concentrations in foals. Methods: 36 foals. Methods: Blood samples were collected from foals before suckling and at 12 and 24 to 36 hours after birth. Plasma IgG concentrations were determined via a commercial single radial immunodiffusion (RID) assay. By use of goat anti-equine IgG antiserum and a spectrophotometer, a TIA was developed to measure plasma and serum IgG concentrations; the percentage light transmission was calibrated against RID assay-determined IgG concentrations. Assay repeatability and effects of seri...