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Topic:Veterinary Research
Veterinary research in horses encompasses the study of diseases, health management, and medical treatments specific to equine species. This field investigates various aspects of horse health, including infectious diseases, metabolic disorders, and musculoskeletal conditions. Researchers focus on understanding the pathophysiology of equine ailments, developing diagnostic tools, and evaluating therapeutic interventions. The study of horse health also involves examining preventive measures such as vaccination protocols and nutritional management to promote overall well-being. This page collects peer-reviewed research studies and scholarly articles that explore the diverse areas of veterinary science related to horses, providing insights into disease mechanisms, treatment strategies, and advancements in equine healthcare.
Tissue-specific gene expression as an indicator of epididymis-specific functional status in the boar, bull and stallion. cDNA probes derived from genes expressed specifically in the human epididymis were used to examine gene expression in the epididymides of boar, bull and stallion by Northern hybridization. Two probes for the HE1 and HE4 gene products were found to recognize tissue-specific transcripts in all three species, with a regionally differential distribution within the epididymis. Additionally, antibodies recognizing the HE4 protein were shown to react specifically in the epididymis of the boar and bull. An extensive study of the boar showed that, whereas mRNA for the HE1-homologue was up-regulated mar...
Thromboxane A2 receptors in equine monocytes: identification of a new subclass of TXA2 receptors. Thromboxane (TX) A2 has been implicated as an important pathophysiologic mediator of a variety of cardiovascular diseases. Monocytes synthesize TXA2 and it modulates their function. This study sought to characterize monocyte TXA2 receptors. Radioligand binding studies were performed on membranes prepared from equine peripheral blood monocytes using [125I]BOP, a TXA2 receptor agonist. [125I]BOP bound to a single class of binding sites (Kd = 1.0 +/- 0.3 nM and Bmax = 389 +/- 191 fmol/mg protein; n = 5). Several TXA2 receptor agonists and antagonists competed for binding with [125I]BOP. I-BOP pro...
Bilateral optic disc colobomas and microphthalmos in a thoroughbred horse. A thoroughbred colt had bilateral but unequal microphthalmos together with microcornea, abnormalities of the iris and lens and posterior segment colobomas. The case is compared with other reports of microphthalmos and coloboma in horses.
Equine lutropin and chorionic gonadotropin bear oligosaccharides terminating with SO4-4-GalNAc and Sia alpha 2,3Gal, respectively. Equine chorionic gonadotropin (eCG) and lutropin (eLH) are heterodimeric glycoprotein hormones which are synthesized in the placenta and pituitary, respectively. The beta subunits of eCG and eLH, like their alpha subunits, arise from a single gene and have identical amino acid sequences. In contrast, the beta subunits of CG and LH in primates arise from different genes and differ in sequence. We have examined the structures of the Asn-linked oligosaccharides on eCG and eLH. eCG bears di- and tri-branched Asn-linked oligosaccharides terminating with Sia alpha 2,3 or 6Gal beta 1,4GlcNAc. In cont...
Echinococcus granulosus hydatid cysts in the livers of two horses. No abstract available
Current status of the diagnosis and control of African horse sickness. African horse sickness (AHS) is an infectious, non-contagious, highly fatal viral disease of Equidae, transmitted by arthropod vectors of the genus Culicoides, and endemic in Africa south and east of the Sahara. The disease is caused by a virus of the Reoviridae family, genus Orbivirus, and 9 serotypes have been recognized. Recent outbreaks of AHS in the Iberian peninsula and Northern Africa emphasize the need for accurate diagnosis and rapid implementation of control measures. In this paper, the epizootiological factors, clinical signs and necropsy findings of AHS are discussed, and an update...
Vertebral angiosarcoma in a horse. No abstract available
Qualitative and morphometric radiographic findings in the distal phalanx and digital soft tissues of sound thoroughbred racehorses. Lameness examinations and radiography of the distal phalanx and associated soft-tissue structures of the front feet of 103 Thoroughbred racehorses, 4 to 9 years old, were performed to determine normal radiographic appearance and morphometry. Of 103 horses examined, 41 were used in the study that were without clinical signs of foot problems or lameness, had raced at least twice prior to radiography, and had raced at least twice more in the 6 months after radiography. Lateromedial and dorsoproximal-palmarodistal radiographic views of each front distal phalanx were used to measure 28 bone and sof...
A review of techniques for the serologic diagnosis of equine infectious anemia. No abstract available
Segmental ischemic necrosis of the small intestine in two postparturient mares. Two mares developed segmental ischemic necrosis of the small intestine after parturition. In one mare, the mesentery of the small intestine apparently tore during parturition, after which necrosis developed in a 52-cm segment of the distal portion of jejunum. In the other mare, a 52-cm segment of the proximal portion of ileum tore during parturition. Three weeks later, a 40-cm segment of the distal portion of jejunum became incarcerated in the mesenteric rent and twisted 360 degrees on its mesentery. Both mares recovered after resection of affected intestine and are functioning as broodmares.
Serum concentrations of ormetoprim/sulphadimethoxine in 1-3-day-old foals after a single dose of oral paste combination. Ormetoprim (OMP)/sulphadimethoxine (SDM) combinations
have been used in the treatment of fowl cholera, colibacillosis,
salmonellosis, infectious coryza, and other bacterial infections in
poultry (Mitrovic et al. 1969; Maestrone et al. 1979). The drug
combination has also been used in the treatment of colibacillosis
in neonatal pigs (Brandt and Maestrone 1980) and Pasteurella
pneumonia in cattle (Ames et al. 1987). Serum concentrations and
pharmacokinetics of SDM (Oh-Ishi and Nakajima 1964; Durr et
al. 1980) and OMP/SDM (Brown et al. 1989) after intravenous or
oral administration to ad...
Technique for long-term right dorsal colon fistulization in ponies. Right dorsal colon fistulas, 2.5 cm in diameter, were created in 2 healthy ponies, using a 2-stage surgical procedure. The first stage consisted of resection of portions of the 16th and 17th ribs on the right side, followed by surgical creation of a 6- to 8-cm-diameter adhesion between the right dorsal colon and the body wall. Fistulas were created approximately 2 weeks after the first surgery by sharp dissection through the adhesion into the lumen of the colon. The fistulas have been satisfactorily maintained for > 2 years by de Pezzer catheters (45 F). Ponies with fistulas have been used ...
Clostridium difficile associated with typhlocolitis in an adult horse. No abstract available
A comparative review of human and equine leucocyte differentiation antigens. Monoclonal antibody technology has allowed the recognition and study of numerous leucocyte antigens in man and laboratory animals for over a decade. Numerous advances in the understanding of immune responses and immunopathology have resulted. In recent years equine researchers have started to develop similar reagents, which now offer a powerful tool to investigators of equine immunology and disease.
[Biological and parasitic variations in horses infested and reinfested by Trichinella spiralis]. Seven mares were infected with 20,000 Trichinella spiralis larvae; 2 of them were reinfected 22 wk later with the same amount of larvae. The course of infection in horses was assessed by serology (ELISA), biochemistry (aldolase activity), parasitology and histopathology. In each animal, infection was followed by a significant rise in specific antibody titers culminating at 5-10 wk post-infection (pi) and decreasing thereafter. Reinfection was followed by a slight rise in antibody levels. Aldolase activity increased during the first infection, but was not modified by reinfection. The parasite b...
Epizootic of equine influenza in 1969 in Poland. Epidemiological observations on the course and spread of equine influenza in Poland during the 1969 epizootic were carried out. The dynamics of the spread of the disease in the country are shown graphically by voivodship. The disease incidence and mortality rates for the entire country are also shown. The highest incidence of disease and mortality rates were found to be in November 1969. A/equi-2/Warsaw/69 was identified as the causal virus. It caused the largest epizootic in the country since 1954.
The estimation of factor VIII levels in horse, cattle, sheep and pig plasma by the use of synthetic chromogenic substrate. Factor VIII level in horse, cattle, sheep and pig plasma was estimated by the use of synthetic chromogenic substrate S-2222 (benzoyl-isoleucyl-glutamyl-glycyl-arginyl-p-nitronilide). The highest level of this factor was stated in pig, the lowest one in sheep plasma.
Equine protozoal myeloencephalitis: antigen analysis of cultured Sarcocystis neurona merozoites. Antigens of cultured Sarcocystis neurona merozoites were examined using immunoblot analysis. Blotted proteins were probed with S. cruzi, S. muris, and S. neurona antisera produced in rabbits, S. fayeri (pre- and post-infection) and S. neurona (pre- and post-inoculation) sera produced in horses, immune sera from 7 histologically confirmed cases of equine protozoal myeloencephalitis (EPM), and pre-suckle serum from a newborn foal. Eight proteins, 70, 24, 23.5, 22.5, 13, 11, 10.5, and 10 Kd, were detected only by S. neurona antiserum and/or immune serum from EPM-affected horses. Equine sera were ...
