Veterinary science and horses encompass the study and application of medical, surgical, and therapeutic practices to maintain and improve the health and welfare of equines. This field addresses a wide range of topics, including disease prevention, diagnosis, and treatment, as well as nutrition, reproduction, and behavior. Research in veterinary science for horses often involves understanding the pathophysiology of equine-specific diseases, developing advanced diagnostic techniques, and improving treatment protocols. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary science related to horses, providing insights into the latest advancements and methodologies in equine healthcare.
Nielsen SS, Alvarez J, Boklund A, Dippel S, Dorea F, Figuerola J, Herskin M, Miranda Chueca MA, Nannoni E, Nonno R, Riber A, Stahl K, Stegeman JA....Horses of different ages may have to be killed on-farm for purposes other than slaughter (where slaughter is defined as killing for human consumption) either individually (i.e. on-farm killing of unproductive, injured or terminally ill animals) or on a large-scale (i.e. depopulation for disease control purposes and other situations, such as environmental contamination, disaster management, etc.). The purpose of this opinion is to assess the hazards and welfare consequences associated with the on-farm killing of horses. The killing procedure is divided into Phase 1 (pre-killing), which includes...
Ishihara T, Nieves E, Reed R, Hofmeister E.Dobutamine is used to treat hypotension in isoflurane-anaesthetised horses but may produce arrhythmias. Halothane is a volatile anaesthetic that was, historically, widely used in horses, but in one study, 56 of 200 halothane-anaesthetised horses (28%) developed arrhythmias after dobutamine administration. Although isoflurane has largely replaced halothane, it is unknown how isoflurane and dobutamine interact in the development of arrhythmias. Methods: The medical records of horses undergoing general anaesthesia at the University of Georgia Veterinary Teaching Hospital in 2015 were reviewed ret...
Perera TRW, de Ruijter-Villani M, Gibb Z, Nixon B, Sheridan A, Stout TAE, Swegen A, Skerrett-Byrne DA.Embryo-maternal signaling during the establishment of pregnancy in horses remains one of the biggest mysteries in large animal physiology. Early pregnancy loss represents a major source of economic loss to the breeding industry. This study aimed to investigate the systemic changes associated with early pregnancy by mapping the proteome of blood plasma at 14 days in pregnant and non-pregnant mares. Methods: Plasma proteomes were analysed in commercially bred pregnant (n = 17) and non-pregnant (n = 17) Thoroughbred mares at 14 days after ovulation, using high-resolution mass spectrometry. D...
Hinrichs K, Schnobrich M, Fernandes CB, Fleury P, Barillari V, Bruggeworth S.Transvaginal ultrasound-guided follicle aspiration (TVA) is being performed commonly in clinical equine practice. There is limited information in the literature about the type and incidence of complications related to TVA. We conducted a survey (Study 1), completed by 23 practicing veterinarians, soliciting information about the types and incidence of minor and major complications and of fatalities they had experienced associated with performance of TVA. In Study 2, data from a large clinical practice in which six veterinarians performed over 14,000 TVAs over a period of 7 years was reviewed t...
Drzewiecka EM, Molcan T, Sadowska A, Piotrowska-Tomala K, Słyszewska M, Dias GF, Skarżyński DJ, Szóstek-Mioduchowska A.Mares with endometrosis exhibit histological changes not only in the endometrium but also in the myometrium that suggest possible functional impairment. The molecular background of these changes is not well understood. We hypothesize that the transcriptomic profile of the mare myometrium varies depending on the degree of endometrosis in mares. Myometria were collected from mares in the mid-luteal phase of the estrous cycle with endometrium categories I, IIA, IIB, and III (∑n = 23), according to Kenney and Doig´s histopathological classification. Myometrial RNA was isolated and subjected...
Caddey B, Fisher S, Barkema HW, Nobrega DB.SUMMARYNumerous questions persist regarding the role of companion animals as potential reservoirs of antimicrobial-resistant organisms that can infect humans. While relative antimicrobial usage in companion animals is lower than that in humans, certain antimicrobial-resistant pathogens have comparable colonization rates in companion animals and their human counterparts, which inevitably raises questions regarding potential antimicrobial resistance (AMR) transmission. Furthermore, the close contact between pets and their owners, as well as pets, veterinary professionals, and the veterinary clin...
Wang J, Ren W, Li Z, Ma S, Li L, Wang R, Zeng Y, Meng J, Yao X.This study aims to analyze the whole-genome DNA methylation differences in Yili horses before and after racing, with the goal of identifying differentially methylated genes associated with racing performance and exploring the epigenetic mechanisms underlying exercise in horses. Blood samples were collected from the jugular veins of the top 3 Yili horses in a 5000 m race, which included 25 competitors, both prior to and within 5 min after the race. Genomic DNA was extracted, followed by sequencing using Whole-Genome Bisulfite Sequencing (WGBS) to assess DNA methylation levels, differentially me...
Sharma S, Reardon LM, Guda R, Carr MM, Man LX, Alicea D.Our primary objective was to identify and describe demographic trends in head and neck injuries incurred while participating in horseback riding. Methods: Cross-sectional analysis. Methods: National Database. Methods: Head and neck injuries related to horseback riding over a ten-year period (2014-2023) were analyzed using data from the National Electronic Injury Surveillance System (NEISS). A total of 3,177 cases were identified. Inclusion criteria encompassed injuries to the head, neck, face, mouth, or ear. Variables included age, gender, injury type, anatomical location, and patient disposit...
Rossi HS, Mykkänen AK, Junnila JJT, Hyytiäinen HK.Pulse oximetry has not been thoroughly evaluated for assessment of oxygenation in conscious foals. Compared with invasive arterial blood sampling, it is a painless and non-invasive method for real-time monitoring of blood oxygen saturation. The aim of this prospective clinical study was to evaluate the usability, validity, and reliability of pulse oximetry at two measuring sites (lip and caudal abdominal skin fold) for blood oxygen saturation measurement in conscious foals with and without respiratory compromise. Thirty-two foals under one month of age were used. Nineteen foals had normal resp...
Shi Y, Maga EA, Mienaltowski MJ.Diarrhea is a common disease that could threaten the welfare of newborn foals. While there are several forms of foal diarrhea, the etiologies can be considered known pathogenic or non-pathogenic in nature. Moreover, there are likely differences in the composition of microbial populations in the gastrointestinal tracts of foals depending upon the etiology of diarrhea. Our study aims to examine the microbial population in the feces of foals with both pathogenic and non-pathogenic diarrheas to discern differences in their microbial compositions. Results: Foal diarrhea samples tested positive or n...
The AnalystJanuary 23, 2025
doi: 10.1039/d4an01501k
Göktaş EF, Kabil E, Söylemez Yeşilçimen E, Dirikolu L.Various technical methodologies are required to accurately detect substances of different chemical and pharmacological properties in biological samples, which are increasing in number and variety daily. Therefore, laboratories where many samples and different factors are analyzed simultaneously need methods with easy sample preparation, short analysis times and low analysis costs. In this study, the objective was to scan substances susceptible to chemical degradation, amenable to analysis without hydrolysis, and exhibiting short-term stability by employing a straightforward, expeditious, and c...
Nowicka B, Polkowska I, Zeliszewska-Duk P, Torres A, Duk M.Similarly, in humans and horses, thoracic and lumbosacral back pain cause more disability and work interruptions worldwide than any other disease. Given that there are few effective treatments for back pain in humans and animals, primary prevention strategies and a reduction in pain factors may be crucial. In the analysed data obtained for the horses studied, the pattern of changes in adipocytokine concentrations, including resistin, visfatin and leptin, was noted for those with back pain compared to the control animals. Concentrations of selected adipocytokines in horses from the back pain gr...
Haussler KK, le Jeune SS, MacKechnie-Guire R, Latif SN, Clayton HM.The defining characteristic of laterality is the dominance of one side of the brain controlling specific functions of paired organs or on one side of the body. Structural and functional asymmetries are ubiquitous in horses and range from anatomical features (e.g., the length of long bones) to the gathering of sensory information (e.g., which eye is used to observe unfamiliar scenes) and motor functions (e.g., left-right differences in locomotion). There is a common tendency to assign observed structural or functional asymmetries to lateralization, which often involves more than a simple left-r...
Nakase M, Thapa J, Batbaatar V, Khurtsbaatar O, Enkhtuul B, Unenbat J, Lkham B, Fujita S, Koshikawa A, Tuanyok A, Saechan V, Higashi H, Hayashida K....Glanders and melioidosis are contagious zoonotic diseases caused by Burkholderia mallei and B. pseudomallei, respectively. Bacterial isolation and polymerase chain reaction (PCR) have been used to detect these bacteria in animals suspected of infection; however, both methods require skilled experimental techniques and expensive equipment. These obstacles make it difficult to diagnose B. mallei and B. pseudomallei infections in areas where reagents and equipment are difficult to procure. To solve this problem, we developed an easy and ready-to-use dried-format diagnostic tool based on loop-medi...
Clayton HM, Hobbs SJ, Rhodin M, Hernlund E, Peterson M, Bos R, Bragança FS.Prior to international competitions, dressage horses are evaluated for fitness to compete while trotting in hand on a firm surface. This study compares the kinematics of experienced dressage horses trotting under fitness-to-compete conditions vs. performing collected and extended trot when ridden on a sand-fiber arena surface. The hypotheses are that the vertical range of motion (ROM) and left-right asymmetries in minimal and maximal heights of axial body segments at ridden trot exceed those when trotting in hand. Inertial measurement units (IMUs) attached mid-dorsally to the head, withers, an...
Laffi L, Bigand F, Peham C, Novembre G, Gamba M, Ravignani A.Anecdotally, horses' gaits sound rhythmic. Are they really? In this study, we quantified the motor rhythmicity of horses across three different gaits (walk, trot, and canter). For the first time, we adopted quantitative tools from bioacoustics and music cognition to quantify locomotor rhythmicity. Specifically, we tested whether kinematics data contained rhythmic categories; these occur when adjacent temporal intervals are categorically, rather than randomly, distributed. We extracted the motion cycle duration (t) of two ipsilateral hooves from motion data of 13 ridden horses and calculated th...
Shinn LT, Wagner CB, Desai R, Marini BL.Horse antithymocyte globulin carries a black box warning for life-threatening anaphylactic reactions, and prescribing information recommends test doses to identify patients at highest risk of this adverse effect. The predictive value of such test doses is not well validated, and practicality of use is unclear. Methods: This was a planned secondary analysis of a multicenter, retrospective cohort study in adults with severe aplastic anemia being managed with horse antithymocyte globulin as part of their treatment regimen. Qualitative and quantitative descriptions of test doses and infusion react...
Klitzing L, Kirsch K, Schindler M, Merle R, Hoffmann G, Thöne-Reineke C, Wiegard M.The novel object test is one of the three most common fear tests in veterinary science and employed in several different species. Although having been applied in several different studies in horses, it is surprising that there is no standardized test procedure available for these kinds of tests. Unassigned: This study investigated the performance of the novel object test on 42 young Thoroughbred horses to determine the effect of sex (mare or stallion), test sites (round pen or paddock) and whether the horses had previously participated in an auction or not on the behavior during the novel obje...
Barshick MR, Ely KM, Mogge KC, Chance LM, Johnson SE.Methylsulfonylmethane (MSM) is a sulfur-containing molecule with reported anti-inflammatory and antioxidant activities. Exercise causes the formation of free radicals and stimulates inflammatory gene expression in leukocytes and skeletal muscle. The hypothesis that dietary supplementation with MSM alters the exercise-mediated inflammatory and oxidant response was assessed in unfit adult thoroughbred geldings. Ten geldings (6.7 ± 1.6 yr) were assigned to a diet supplemented without (CON, = 5) or with 21 g of MSM ( = 5) for 30 days. Following the supplementation period, horses performed a stan...
Byström A, Egenvall A, Eisersiö M, Engell MT, Lykken S, Lundesjö Kvart S.Riding relies on embodied and practical knowledge and is predominantly taught during practical lessons. Effective teaching is dependent on relevant instructions and evaluation from the riding teacher or trainer. The aim was to investigate how riding instructions affect horse and rider motion and rein tension during transitions between walk and trot. Two Swedish (S1, S2) and two Norwegian (N1, N2) riding teachers, and five riders per location participated. Each rider rode two horses, 40 lessons total. Videos, horse and rider kinematics and rein tension were recorded. The teachers were interview...
Torell Palmquist G, Känsälä Alveheim N, Huot-Marchand F, Ashton L, Lewis V.This paper highlights and summarizes the experiences and perceptions of European equestrian educational experts from a workshop held at the French National Riding School in Saumur. The workshop, which brought together fifty leading experts, aimed to address challenges in equestrian education, identify common ground, and share best practices. Using 'The World Café' method, the participants were divided into groups to discuss four key topics: the relationship between horses and humans, diversity of perspectives versus common ground, training philosophy, and social acceptability. A follow-up onl...
Sharma NK, Singh P, Saha B, Bhardwaj A, Iquebal MA, Pal Y, Nayan V, Jaiswal S, Giri SK, Legha RA, Bhattacharya TK, Kumar D, Rai A.Copy number variations (CNVs) have become widely acknowledged as a significant source of genomic variability and phenotypic variance. To understand the genetic variants in horses, CNVs from six Indian horse breeds, namely, Manipuri, Zanskari, Bhutia, Spiti, Kathiawari and Marwari were discovered using Axiom™ Equine Genotyping Array. These breeds differed in agro-climatic adaptation with distinct phenotypic characters. A total of 2668 autosomal CNVs and 381 CNV regions (CNVRs) were identified with PennCNV tool. DeepCNV was employed to re-validate to get 883 autosomal CNVs, of which 9.06% were...
Stafford LS, Plummer CE, Smith WC, Gibson DJ, Sharma J, Vicuna V, Diakite S, Larkin J.Recurrent uveitis (RU), an autoimmune disease, is a leading cause of ocular detriment in humans and horses. Equine and human RU share many similarities including spontaneous disease and aberrant cytokine signaling. Reduced levels of SOCS1, a critical regulator of cytokine signaling, is associated with several autoimmune diseases. Topical administration of SOCS1-KIR, a peptide mimic of SOCS1, was previously correlated to reduced ocular pathologies within ERU patients. Unassigned: To further assess the translational potential of a SOCS1 mimetic to treat RU, we assessed peptide-mediated modulatio...
Whitaker K, Burnette A, Tan JY, Graves M, Hunt J, Devine E, Anderson S, Kirkendall K, Wisnieski L.There is a shortage of equine veterinarians. Understanding what factors are associated with job satisfaction in equine veterinarians can inform interventions to increase retention in equine medicine. Objective: To explore the prominent factors causing work dissatisfaction and burnout in equine veterinarians. Methods: Qualitative research study consisting of semi-structured focus groups. Methods: Thirty-seven current and former equine veterinarians across the United States were recruited via snowball and convenience sampling to answer questions on work history, work-life balance, and perception...
Chodzinski A, Wissing S, Tipold A, Geburek F.The skills necessary to perform diagnostic perineural anesthesia in equids belongs to one of the Day One Competences of a veterinarian, so every veterinary graduate should be able to perform them correctly. For logistical, hygienic and ethical reasons, practical exercises on cadaver limbs are not accessible to all students. Two equine distal limb simulators were developed and evaluated as an additional instructional tool to train the required skills. Both simulators were designed and built with an integrated success control, with Simulator I (S1) designed to be a simplified anatomical model an...
Accorroni L, Bazzano M, Marchegiani A, Spaterna A, Laus F.Knowledge of the normal ultrasound anatomy in the donkey is essential to understand pathological changes and to reach an early diagnosis, considering the "dullness" and stoicism of these animals in pain manifestations. The aims of this study were to document which abdominal viscera could be identified using a transcutaneous ultrasonography technique under field conditions in unsedated, standing donkeys to determine where the different abdominal structures could be easily displayed and to describe any variation that occurred between different donkeys and horses. In this work, the manual techniq...
Chanutin S, Bauck AG, Roberts JF, Denagamage TN, Freeman DE.Jejunocaecostomy (JC) is frequently required to bypass diseased ileum as a side-to-side (SS) anastomosis with blind end closure of the small intestine. The effects of the blind end closure method on the performance of the anastomosis have not been studied. Objective: To compare handsewn and stapled blind end closures of the ileum and jejunum. Methods: In vivo experiments. Methods: JC was performed with either Parker-Kerr (PK; 6 horses) or oversewn stapled technique (OS; 6 horses) to close jejunum and ileum for an SS anastomosis. At surgery, peritoneal fluid was analysed and various anastomotic...
Albert E, Biksi I, Laczkó L, Miló L, Cseri K, Bőkényné Tóth R, Papp D, Halmay D, Bódai E, Bakos Z.Here we report the isolation of Streptococcus hillyeri from a thoracic sample from a horse. A 17-y-old Hungarian Sport Horse mare was referred to the equine clinic of the University of Veterinary Medicine Budapest, Hungary, with suspected pleuritis. Upon arrival, the horse was febrile and had tachycardia, severe inspiratory dyspnea, and tachypnea. Thoracic ultrasonography revealed severe bilateral pleural effusion, and a large area of lung consolidation. After sampling of both hemithoraces, 66 L of turbid exudate were drained. Based on these findings, a tentative diagnosis of septic pleuritis ...
Holst BS, Engelmann A, Gröndahl G, Gunnarsson L, Haug Haaland A, Hielm-Björkman A, Moe L, Rhodin M, Rönnberg H, Stråhle M, Toljander Y....The societal value of cats, dogs and horses is high, and the companion and sport animal health care sector is growing. Clinical research concerning cats, dogs and horses is crucial for the development of evidence-based medical care that benefits animals and their owners, and has implications for human and environmental health from a One Health perspective. Basic information on companion animal and equine research enables more directed measures to improve conditions for research within the area. The aim of the present study was to describe Nordic companion animal and equine clinical research fr...
Jaworska J, Tobolski D, Salem SE, Kahler A, Wocławek-Potocka I, Mestre AM.Embryo implantation in the mare occurs just over one month after fertilization, coinciding with the production of chorionic gonadotropin. The factors that regulate this late implantation in the mare, and whether they are unique to horses or shared with more invasive embryo implantation in other species, remain poorly understood. This study aimed to determine and compare the transcriptome and subpopulations of endometrial cells before and after embryo implantation in the horse. Single-cell RNA sequencing was used to characterize the transcriptome of nearly 97,000 endometrial cells collected fro...
Kouam MK, Kantzoura V, Gajadhar AA, Theis JH, Papadopoulos E, Theodoropoulos G.Serum samples were collected from a total of 544 equids that included 524 horses, 13 mules, and 7 ponies from various regions of mainland Greece and were examined by competitive-inhibition ELISA (cELISA) to evaluate the level of exposure of Greek equids to Theileria (Babesia) equi and/or Babesia caballi, the causative agents of piroplasmosis. Association between seropositivity and host-related factors of species, gender, age, origin, activity and location were investigated. The overall seroprevalence was 11.6% (9.1-14.6%) with 95% confidence limit. The seroprevalence for T. equi and B. caballi...
Leblond A, Hendrikx P, Sabatier P.Recent outbreaks of West Nile virus-associated (WNV) diseases, both in the old World and Americas, underline the importance for early warning systems that rapidly identify emerging and re-emerging diseases and thus help in their control. Traditional approaches of disease monitoring become less reliable and increasingly costly when used for rare health-related events, such as WNV outbreaks in southern France. The objective of this work was to discuss methodological issues related to syndromic monitoring of WNV-associated disease in Camargue horses by veterinary practitioners. Tracking cases of ...
The Journal of heredityFebruary 28, 2013
Volume 104, Issue 3 386-398 doi: 10.1093/jhered/est003
Khanshour A, Conant E, Juras R, Cothran EG.The Arabian horse ignites imagination throughout the world. Populations of this breed exist in many countries, and recent genetic work has examined the diversity and ancestry of a few of these populations in isolation. Here, we explore 7 different populations of Arabians represented by 682 horses. Three of these are Middle Eastern populations from near the historical origin of the breed, including Syrian, Persian, and Saudi Arabian. The remaining Western populations are found in Europe (the Shagya Arabian and Polish Arabian) and in America (American Arabian). Analysis of genetic structure was ...
Tozaki T, Kakoi H, Mashima S, Hirota K, Hasegawa T, Ishida N, Miura N, Choi-Miura NH, Tomita M.Microsatellite 15 TKY System was characterized for parentage verification of horse registry. The Microsatellite 15 TKY System was constructed by using 15 microsatellites, TKY279, TKY287, TKY294, TKY297, TKY301, TKY312, TKY321, TKY325, TKY333, TKY337, TKY341, TKY343, TKY344, TKY374, and TKY394, to provide stringent PCR-based microsatellite typing specifically optimized for multicolor fluorescence detection. The Microsatellite 15 TKY System showed good resolutions for 250 unrelated Thoroughbred horses, and the probability of exclusion (PE) at each microsatellite ranged from 0.437 to 0.621, resul...
Human movement scienceDecember 14, 2004
Volume 23, Issue 5 663-671 doi: 10.1016/j.humov.2004.10.006
Peham C, Licka T, Schobesberger H, Meschan E.The aim of this study was to show that the motion pattern of a well-ridden horse varies less than the motion pattern of an unridden horse. In order to do so, we recorded the motion of two markers, one attached to the dorsal spinous processus of lumbar vertebra L4, the other to the right fore hoof. In total, we measured 21 horses in trot, ridden and unridden, with a fitting and with a non-fitting saddle. After breaking down the entire time series of the three-dimensional motion of the markers into their respective motion cycles, we computed a measure of motion pattern variability for the motion...
Ireland JJ, Roberts RM, Palmer GH, Bauman DE, Bazer FW.Research on domestic animals (cattle, swine, sheep, goats, poultry, horses, and aquatic species) at land grant institutions is integral to improving the global competitiveness of US animal agriculture and to resolving complex animal and human diseases. However, dwindling federal and state budgets, years of stagnant funding from USDA for the Competitive State Research, Education, and Extension Service National Research Initiative (CSREES-NRI) Competitive Grants Program, significant reductions in farm animal species and in numbers at land grant institutions, and declining enrollment for graduate...
Edson D, Field H, McMichael L, Jordan D, Kung N, Mayer D, Smith C.Bats of the genus Pteropus (flying-foxes) are the natural host of Hendra virus (HeV) which periodically causes fatal disease in horses and humans in Australia. The increased urban presence of flying-foxes often provokes negative community sentiments because of reduced social amenity and concerns of HeV exposure risk, and has resulted in calls for the dispersal of urban flying-fox roosts. However, it has been hypothesised that disturbance of urban roosts may result in a stress-mediated increase in HeV infection in flying-foxes, and an increased spillover risk. We sought to examine the impact of...
Bourée P.Hydatidosis is a widespread zoonosis infecting a large number of animals and humans. Echinococcus granulosus has the smallest taenia adult of the cestodes but with the largest larva. Its morphologic and biologic features were identified with DNA analysis. Different strains were separated according to the intermediate hosts: sheep, cattle, pigs, horses, camels. Definitive host are canids, mostly dogs, where the worm grows to adulthood in several months. The eggs are scattered in the pasture by wind and water and are ingested by various hosts. The larvae migrate through the intestinal wall and p...
Rivero JL, Ruz A, Martí-Korff S, Estepa JC, Aguilera-Tejero E, Werkman J, Sobotta M, Lindner A.This study examined the effects of the intensity and duration of exercise on the nature and magnitude of training adaptations in muscle of adolescent (2-3 yr old) racehorses. Six thoroughbreds that had been pretrained for 2 mo performed six consecutive conditioning programs of varying lactate-guided intensities [velocities eliciting blood lactate concentrations of 2.5 mmol/l (v2.5) and 4 mmol/l (v4), respectively] and durations (5, 15, 25 min). Pre- and posttraining gluteus muscle biopsies were analyzed for myosin heavy chain content, fiber-type composition, fiber size, capillarization, and fi...
Aberle KS, Hamann H, Drögemüller C, Distl O.We compared the genetic diversity and distance among six German draught horse breeds to wild (Przewalski's Horse), primitive (Icelandic Horse, Sorraia Horse, Exmoor Pony) or riding horse breeds (Hanoverian Warmblood, Arabian) by means of genotypic information from 30 microsatellite loci. The draught horse breeds included the South German Coldblood, Rhenish German Draught Horse, Mecklenburg Coldblood, Saxon Thuringa Coldblood, Black Forest Horse and Schleswig Draught Horse. Despite large differences in population sizes, the average observed heterozygosity (H(o)) differed little among the heavy ...
Luna D, Tadich TA.The livelihood of working horses' owners and their families is intimately linked to the welfare of their equids. A proper understanding of human-animal interactions, as well as the main factors that modulate them, is essential for establishing strategies oriented to improve the welfare of animals and their caretakers. To date, there is still a paucity of research dedicated to the identification and assessment of the human psychological attributes that affect the owner⁻equine interaction, and how these could affect the welfare of working equids. However, some studies have shown that empathy, ...
Corrin T, Ackford R, Mascarenhas M, Greig J, Waddell LA. Eastern equine encephalitis virus (EEEV) is a mosquito-borne virus that is primarily found in North America and the Caribbean. Over the past decade there has been an increase in virus activity, including large outbreaks in human and horse populations. Predicted climate change is expected to affect the range of mosquitoes including vectors of EEEV, which may alter disease risk posing a public health concern. A scoping review (ScR) was conducted to identify and characterize the global evidence on EEEV. A thorough search was conducted in relevant bibliographic databases and government websites....
Miao Q, Wang X, She LN, Fan YT, Yuan FZ, Yang JF, Zhu XQ, Zou FC.Toxoplasma gondii is an intracellular protozoan parasite that infects almost all warm-blooded animals, including humans, with a worldwide distribution. There have been limited reports about the seroprevalence of T. gondii infection in equids around the world and little is known about the seroprevalence of T. gondii in equids in southwestern China, in particular in Yunnan Province. The objective of the present investigation was to estimate the seroprevalence of T. gondii infection in equids in this area. Methods: A total of 399 serum samples (266 from horses and 133 from donkeys) were collected...
Redaelli V, Luzi F, Mazzola S, Bariffi GD, Zappaterra M, Nanni Costa L, Padalino B.The aim of this pilot study was to document the effects of endurance training at different intensities on heart rate (HR), blood count, serum cortisol, and maximal temperatures of different body locations, namely eye, crown, pastern pasterns, and muscle (, measured by infrared thermography technique (IRT) in horses trained for endurance. Possible associations among the studied parameters were also investigated. Our hypothesis was that temperature, measured by IRT after endurance training of different intensities would vary depending on the intensity and would be positively correlated with HR...
Hartel PG, Summer JD, Hill JL, Collins JV, Entry JA, Segars WI.Several genotypic methods have been developed for determining the host origin of fecal bacteria in contaminated waters. Some of these methods rely on a host origin database to identify environmental isolates. It is not well understood to what degree these host origin isolates are geographically variable (i.e., cosmopolitan or endemic). This is important because a geographically limited host origin database may or may not be universally applicable. The objective of our study was to use one genotypic method, ribotyping, to determine the geographic variability of the fecal bacterium, Escherichia ...
Malavasi R, Huber L.Referential communication occurs when a sender elaborates its gestures to direct the attention of a recipient to its role in pursuit of the desired goal, e.g. by pointing or showing an object, thereby informing the recipient what it wants. If the gesture is successful, the sender and the recipient focus their attention simultaneously on a third entity, the target. Here we investigated the ability of domestic horses (Equus caballus) to communicate referentially with a human observer about the location of a desired target, a bucket of food out of reach. In order to test six operational criteria ...
Hendrickson SL.Life at high altitude results in physiological and metabolic challenges that put strong evolutionary pressure on performance due to oxidative stress, UV radiation and other factors dependent on the natural history of the species. To look for genes involved in altitude adaptation in a large herbivore, this study explored genome differentiation between a feral population of Andean horses introduced by the Spanish in the 1500s to the high Andes and their Iberian breed relatives. Results: Using allelic genetic models and Fst analyses of ~50 K single nucleotide polymorphisms (SNPs) across the horse...
Anggakusuma , Brown RJP, Banda DH, Todt D, Vieyres G, Steinmann E, Pietschmann T.Multiple novel members of the genus Hepacivirus have recently been discovered in diverse mammalian species. However, to date, their replication mechanisms and zoonotic potential have not been explored in detail. The NS3/4A serine protease of hepatitis C virus (HCV) is critical for cleavage of the viral polyprotein. It also cleaves the cellular innate immune adaptor MAVS, thus decreasing interferon (IFN) production and contributing to HCV persistence in the human host. To investigate the conservation of fundamental aspects of the hepaciviral life cycle, we explored if MAVS cleavage and suppress...
Barton MD, Hughes KL.A selective broth enrichment technique was used to study the distribution of Rhodococcus equi in soil and grazing animals. Rhodococcus equi was isolated from 54% of soils examined and from the gut contents, rectal faeces and dung of all grazing herbivorous species examined. Rhodococcus equi was not isolated from the faeces or dung of penned animals which did not have access to grazing. The isolation rate from dung was much higher than from other samples and this was found to be due to the ability of R. equi to multiply more readily in dung. Delayed hypersensitivity tests were carried out on ho...
Christensen JW, Rundgren M, Olsson K.Responses of horses in frightening situations are important for both equine and human safety. Considerable scientific interest has been shown in development of reactivity tests, but little effort has been dedicated to the development of appropriate training methods for reducing fearfulness. Objective: To investigate which of 3 different training methods (habituation, desensitisation and counter-conditioning) was most effective in teaching horses to react calmly in a potentially frightening situation. Objective: 1) Horses are able to generalise about the test stimulus such that, once familiar w...
Neill CL, Hansen CR, Salois M.The purpose of this study is to estimate the economic cost of burnout in the veterinary profession and highlight the financial reasons why the industry should address the burnout crisis from an organizational perspective. Using data from 5,786 associate veterinarians in private practice, information was obtained using employment information related to compensation, work hours, hour preferences, and job turnover. Burnout was measured using the Professional Quality of Life Scale and used to calculate conditional probabilities on turnover and reduced working hours due to burnout. Lost revenue fro...
Venter M, Pretorius M, Fuller JA, Botha E, Rakgotho M, Stivaktas V, Weyer C, Romito M, Williams J.During 2008-2015 in South Africa, we conducted West Nile virus surveillance in 1,407 animals with neurologic disease and identified mostly lineage 2 cases in horses (7.4%, 79/1,069), livestock (1.5%, 2/132), and wildlife (0.5%, 1/206); 35% were fatal. Geographic correlation of horse cases with seropositive veterinarians suggests disease in horses can predict risk in humans.
Taylor SE, Smith RK, Clegg PD.The goal in the therapeutic use of mesenchymal stem cells (MSCs) in musculoskeletal disease is to harness the regenerative nature of these cells focussing on their potential to grow new tissues and organs to replace damaged or diseased tissue. Laboratory isolation of MSCs is now well established and has recently been demonstrated for equine MSCs. Stem cell science has attracted considerable interest in both the scientific and clinical communities because of its potential to regenerate tissues. Research into the use of MSCs in tissue regeneration in general reflects human medical needs, however...
Griffin TM, Kram R, Wickler SJ, Hoyt DF.We studied nine adult horses spanning an eightfold range in body mass (M(b)) (90-720 kg) and a twofold range in leg length (L) (0.7-1.4 m). We measured the horses' walk-trot transition speeds using step-wise speed increments as they locomoted on a motorized treadmill. We then measured their rates of oxygen consumption over a wide range of walking and trotting speeds. We interpreted the transition speed results using a simple inverted-pendulum model of walking in which gravity provides the centripetal force necessary to keep the leg in contact with the ground. By studying a large size range of ...
Rioja-Lang FC, Connor M, Bacon H, Dwyer CM.Equine welfare issues are receiving increasing attention in the UK, but welfare problems can arise from a wide range of causes. In order to identify the most important welfare concerns for horses, we used a Delphi method with 19 equine welfare experts. An initial list of 84 equine welfare issues was generated using an online discussion board and NVivo thematic analysis. Subsequently, experts ranked these welfare issues for perceived prevalence, severity and duration of suffering associated with each issue on a 6-point Likert scale. All issues with a mean score of 3 or above ( = 37) were includ...
Witkowska-Piłaszewicz O, Grzędzicka J, Seń J, Czopowicz M, Żmigrodzka M, Winnicka A, Cywińska A, Carter C.Assuring a high level of animal welfare is a critical aspect of contemporary animal husbandry. Equine athletes begin their careers at a very young age when they are still developing and they are both physically and mentally immature. Lack of scientific knowledge of the stress related to horse racing impedes the development of optimal training programs to attain equilibrium between the best sport results and optimal welfare. This study aimed to determine the influence of the intensity and type of physical activity on peripheral blood cortisol concentration. Thirty untrained Arabians, 9 enduranc...
Pérez DS, Tapia MO, Soraci AL.Fosfomycin (FOS) is a natural bactericidal broad-spectrum antibiotic which acts on proliferating bacteria by inhibiting cell wall and early murein/peptidoglycan synthesis. Bactericidal activity is evident against Gram positive and Gram negative bacteria and can also act synergistically with other antibiotics. Bacterial resistance to FOS may be natural or acquired. Other properties of this drug include inhibition of bacterial adhesion to epithelial cells, exopolysaccharide biofilm penetration, immunomodulatory effect, phagocytosis promotion and protection against the nephrotoxicity caused by ot...
Raspa F, Vervuert I, Capucchio MT, Colombino E, Bergero D, Forte C, Greppi M, Cavallarin L, Giribaldi M, Antoniazzi S, Cavallini D, Valvassori E....Horses are often fed high amounts of starch in their diets despite the well-established benefits of a fibre-based diet to promote gut health and animal welfare. The aim of the present study was to compare the effects of two different diets - one based on high amounts of starch (HS) vs. one base on high amounts of fibre (HF) - on specific parameters of the gut environment across different intestinal compartments of the horse digestive tract. To this end differences in the gastrointestinal environment between HS vs. HF fed horses were assessed in terms of dry matter, organic matter and ash conte...