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Topic:Animal Health

Animal Health encompasses a broad range of topics focused on maintaining and improving the well-being of equine species. This field addresses various aspects of horse care, including disease prevention, diagnosis, treatment, and management of health conditions. Key areas of interest include equine nutrition, vaccination protocols, parasite control, dental care, and the management of chronic conditions such as laminitis and colic. Additionally, animal health research in horses investigates the impact of exercise and training on physical health, the role of genetics in disease susceptibility, and the development of new therapeutic approaches. This page compiles peer-reviewed research studies and scholarly articles that explore the latest advancements, challenges, and best practices in preserving and enhancing the health of horses.
Common clinical findings identified in working equids in low- and middle-income countries from 2005 to 2021.
PloS one    June 5, 2024   Volume 19, Issue 6 e0304755 doi: 10.1371/journal.pone.0304755
Merridale-Punter MS, Wiethoelter AK, El-Hage CM, Patrick C, Hitchens PL.Despite several millions of working equids worldwide, there are few published studies regarding the epidemiology of their health and welfare. Data collected by non-governmental organisations (NGOs) operating in the working equid sphere therefore have important epidemiological value and could be used towards animal health surveillance. The aim of this study was to identify common clinical findings and mortality patterns of working equids in low- and middle-income countries and investigate their epidemiology using data collected from an international NGO. A retrospective analysis was conducted t...
Hematological and Biochemical Effects Associated with Prolonged Administration of the NSAID Firocoxib in Adult Healthy Horses.
Veterinary sciences    June 5, 2024   Volume 11, Issue 6 doi: 10.3390/vetsci11060256
Ignácio FS, Garcia LV, de Souza GG, Amatti LZ, de Barros LD, Bergfelt DR, Camargo GS, de Meira C, de Almeida BFM.Non-steroidal anti-inflammatory drugs (NSAIDs) represent one of the most commonly used classes of drugs in both human and veterinary medicine. However, many clinical side effects have been observed, especially when treatment has been prolonged. While the anti-inflammatory efficacy and safety of repeated administration of firocoxib (Previcox®), which is a selective NSAID COX-2 inhibitor, has been evaluated for short-term use (one to fourteen days), its clinical relevance for longer-term use is not known. As a preliminary study, healthy, adult male and female horses (n = 7) were treated with fi...
Equine helminths: prevalence and associated risk factors in Gamo Gofa Zone, Ethiopia.
Journal of veterinary science    June 5, 2024   Volume 25, Issue 3 e41 doi: 10.4142/jvs.23291
Getahun YA, Tsalke BS, Buzuneh AW, Mejo MM, Habtewold WT.Equines are indispensable in reducing the huge burden on children and women and income generation. On the other hand, minimal attention is given to improving their health and welfare. Objective: This study examined the prevalence and associated risk factors of helminth parasites of equine in the Gamo Gofa Zone. Methods: A cross-sectional study was employed from June 2019 to March 2020. The study districts and were selected purposively based on agroecology whereas selection of study households and animals were performed based on simple random sampling techniques. Identification of nematode, tr...
Blebbistatin as a novel antiviral agent targeting equid herpesvirus type 8.
Frontiers in veterinary science    June 5, 2024   Volume 11 1390304 doi: 10.3389/fvets.2024.1390304
Li L, Cui X, Yu Y, Sun Q, Li W, Li Y, Li S, Chen L, Khan MZ, Wang C, Wang T.Equid herpesvirus type 8 (EqHV-8) poses a significant threat to equine health, leading to miscarriages and respiratory diseases in horses and donkeys, and results in substantial economic losses in the donkey industry. Currently, there are no effective drugs or vaccines available for EqHV-8 infection control. Unassigned: In this study, we investigated the and antiviral efficacy of Blebbistatin, a myosin II ATPase inhibitor, against EqHV-8. Unassigned: Our results demonstrated that Blebbistatin significantly inhibited EqHV-8 infection in Rabbit kidney (RK-13) and Madin-Darby Bovine Kidney (MDB...
Changes of faecal bacterial communities and microbial fibrolytic activity in horses aged from 6 to 30 years old.
PloS one    June 3, 2024   Volume 19, Issue 6 e0303029 doi: 10.1371/journal.pone.0303029
Baraille M, Buttet M, Grimm P, Milojevic V, Julliand S, Julliand V.Horse owners and veterinarians report that from the age of 15, their horses can lose body condition and be more susceptible to diseases. Large intestinal microbiome changes may be involved. Indeed, microbiota is crucial for maintaining the condition and health of herbivores by converting fibres into nutrients. This study aimed to compare the faecal microbiome in horses aged from 6 to 30 years old (yo), living in the same environment and consuming the same diet, in order to assess whether the parameters changed linearly with age and whether there was a pivotal age category. Fifty horses were se...
Equus Caballus Papillomavirus Type 7 is A Rare Cause Of Equine Penile Squamous Cell Carcinomas.
Veterinary journal (London, England : 1997)    June 3, 2024   106155 doi: 10.1016/j.tvjl.2024.106155
Munday JS, Knight CG, Bodaan CJ, Codaccioni C, Hardcastle MR.Penile squamous cell carcinomas (SCCs) are common, potentially life-threatening neoplasms of horses. They are well-recognized to be caused by Equus caballus papillomavirus (EcPV) type 2, although EcPV2 cannot be detected in all cases. A 23-year-old standardbred gelding developed multiple penile in situ and invasive SCCs that contained histological evidence of PV infection. By using both consensus and specific PCR primers, these lesions were found to contain EcPV7 DNA, but not DNA from EcPV2 or any other PV type. To determine how frequently EcPV7 is present in equine penile SCCs, specific prime...
Spatiotemporal pattern and suitable areas analysis of equine influenza in global scale (2005-2022).
Frontiers in veterinary science    June 3, 2024   Volume 11 1395327 doi: 10.3389/fvets.2024.1395327
Ding J, Wang Y, Liang J, He Z, Zhai C, He Y, Xu J, Lei L, Mu J, Zheng M, Liu B, Shi M.Equine influenza (EI) is a severe infectious disease that causes huge economic losses to the horse industry. Spatial epidemiology technology can explore the spatiotemporal distribution characteristics and occurrence risks of infectious diseases, it has played an important role in the prevention and control of major infectious diseases in humans and animals. For the first time, this study conducted a systematic analysis of the spatiotemporal distribution of EI using SaTScan software and investigated the important environmental variables and suitable areas for EI occurrence using the Maxent mode...
Update on the equine grass sickness biobank, database and research project.
The Veterinary record    May 31, 2024   Volume 194, Issue 11 doi: 10.1002/vetr.4361
Wells B.Beth Wells, equine grass sickness project lead at the Moredun Research Institute, encourages vets to report any equine grass sickness cases they encounter and explains how case reports and samples are being used to support research into this complex disease.
Use of recombinant tissue plasminogen activator (rTPA) for treatment of fibrin in the anterior chamber of the horse.
Veterinary medicine and science    May 31, 2024   Volume 10, Issue 4 e1448 doi: 10.1002/vms3.1448
Pereira R, Bowen M, Rapezzano G, Redpath A, Pratt S, Hallowell G.Recombinant intracameral tissue plasminogen activator (rTPA) administration can aid clearance of fibrin from the anterior chamber. In this retrospective multicentre case series, the effect of intracameral rTPA administration to treat fibrin in the anterior chamber resulting from trauma or inflammatory ocular disease was evaluated. Clinical data from 30 treatments in 29 horses were obtained from medical records from 2003 to 2022. Association between time from onset of clinical signs and time for rTPA treatment to effect was studied with regression analysis. Twenty-seven horses (93.1%) had no pr...
Predicted efficacy and tolerance of different dosage regimens of benzylpenicillin in horses based on a pharmacokinetic study with three IM formulations and one IV formulation.
Frontiers in veterinary science    May 31, 2024   Volume 11 1409266 doi: 10.3389/fvets.2024.1409266
Ferran AA, Roques BB, Chapuis L, Kuroda T, Lacroix MZ, Toutain PL, Bousquet-Melou A, Lallemand EA.Benzylpenicillin (BP) is a first-line antibiotic in horses but there are discrepancies between manufacturers and literature recommendations regarding dosing regimen. Objectives of this study were to evaluate pharmacokinetics and local tolerance of four different formulations of BP in adult horses, and to suggest optimized dosing regimen according to the formulation. Unassigned: A cross-over design was used in 3 phases for the intramuscular injection of three different products: procaine BP alone, procaine BP/ benzathine BP combination or penethamate hydriodide were administered IM in the glute...
Changes in plasma metabolite concentrations and enzyme activities in aging riding horses.
Frontiers in veterinary science    May 31, 2024   Volume 11 1345548 doi: 10.3389/fvets.2024.1345548
Asahi Y, Arai T, Tanaka Y.In older horses, basal metabolic rate decreases, and plasma metabolite and hormone concentrations related to energy metabolism change. The occurrence of age-related diseases, which increases in old animals, may enhance inflammatory reactivity (inflammaging). Finding the appropriate treatment for inflammaging at an early stage may prevent various age-related diseases. Changes in metabolite and hormone concentrations and enzyme activities involved in energy metabolism in the plasma of clinically healthy riding horses of various ages were measured to identify biomarkers of inflammaging (persisten...
A case of equine multicentric lymphoma: Clinical, microscopical, and molecular findings.
Open veterinary journal    May 31, 2024   Volume 14, Issue 5 1294-1301 doi: 10.5455/OVJ.2024.v14.i5.24
Silva GF, Ribeiro TE, Cunha R, Salas PB, Guimarães T, Ribeiro MR, Barros G, Carvalho F, Mesquita JR, Amorim I.Although relatively uncommon, lymphoma is the most prevalent haematopoietic neoplasia in horses, and multicentric lymphoma remains the most common presentation of the disease. The pathogenesis of equine lymphoma is still poorly understood and the diagnosis is usually confirmed at an advanced stage of the disease, compromising the prognosis. This study investigated the clinical, pathological, and molecular features of a case of equine multicentric lymphoma. Unassigned: An apparently healthy 5-year-old crossbreed mare hospitalized at the Centre of Animal Reproduction of Vairão, Portugal, sudden...
Jugular venous thrombosis as a risk factor for exercise-induced pulmonary hemorrhage in thoroughbred racehorses.
Open veterinary journal    May 31, 2024   Volume 14, Issue 5 1111-1116 doi: 10.5455/OVJ.2024.v14.i5.4
Shawaf T.Exercise-induced pulmonary hemorrhage (EIPH) is one of the most commonly diagnosed disorders in racehorses. Many EIPH risk factors such as breed, age, high or low environmental temperature, and distance of the race have been studied in racehorses. Unassigned: The aim of this study was to study the relationship between EIPH and the presence of jugular vein thrombose in racehorses. Unassigned: Forty-eight thoroughbred racehorses randomly selected from animals with exercise intolerance due to respiratory disorders were enrolled in the present study. Clinical and tracheobronchoscopy examinations w...
Autoimmune Dermatopathies of Horses.
The Veterinary clinics of North America. Equine practice    May 30, 2024   S0749-0739(24)00027-0 doi: 10.1016/j.cveq.2024.04.001
Marsella R.Autoimmune dermatopathies are not common in horses. These autoimmune diseases can be idiopathic or triggered by an antigen such as drugs, vaccines, or neoplasia. The most common one is pemphigus foliaceus, which manifests as a pustular, crusting eruption. Other more common pustular diseases should be ruled out before considering pemphigus. Vasculitis is relatively common in horses and can be triggered by a variety of antigenic stimulations. Systemic lupus and true idiopathic autoimmune vasculitis are very rare in horses. Every effort should be made to reach a final diagnosis, as the prognosis ...
Effects of telemetry collars on two free-roaming feral equid species.
PloS one    May 30, 2024   Volume 19, Issue 5 e0303312 doi: 10.1371/journal.pone.0303312
Schoenecker KA, King SRB, Hennig JD, Cole MJ, Scasta JD, Beck JL.There are two species of free-roaming feral equids in North America: horses (Equus caballus) and donkeys or "burros" (E. asinus). Both species were introduced as domestic animals to North America in the early 1500s and currently inhabit rangelands across the western United States, Canada, and all continents except Antarctica. Despite their global distribution, little is known about their fine scale spatial ecology. Contemporary research tools to assess space use include global positioning system (GPS) tracking collars, but older models were problematic due to stiff collar belting causing poor ...
Becoming a matter of veterinary concern.
Frontiers in veterinary science    May 30, 2024   Volume 11 1355996 doi: 10.3389/fvets.2024.1355996
Smith R, Pinchbeck G, McGowan C, Ireland J, Perkins E.Horses in Great Britain are living into increasingly older age and are often regarded as friends or family members by their owner. The horse is reliant on their owner to meet their needs and this paper discusses how horse owners frame an issue that becomes a matter of veterinary concern within the context of the older horse. Qualitative methods were used to explore the experiences of owners and veterinarians. Data were collected and analysed using a grounded theory approach during the period 2019-2022. Analysis identified that owners undertook an ongoing and iterative process of assessment, mo...
A possible cause and therapy for equine grass sickness.
Toxicon : official journal of the International Society on Toxinology    May 29, 2024   Volume 245 107790 doi: 10.1016/j.toxicon.2024.107790
Montecucco C, Bano L.No abstract available
Proteomics is advancing the understanding of stallion sperm biology.
Proteomics    May 29, 2024   e2300522 doi: 10.1002/pmic.202300522
Peña FJ, Martín-Cano FE, Becerro-Rey L, Ortega-Ferrusola C, Gaitskell-Phillips G, da Silva-Álvarez E, Gil MC.The mammalian ejaculate is very well suited to proteomics studies. As such, research concerning sperm proteomics is offering a huge amount of new information on the biology of spermatozoa. Among domestic animals, horses represent a species of special interest, in which reproductive technologies and a sizeable market of genetic material have grown exponentially in the last decade. Studies using proteomic approaches have been conducted in recent years, showing that proteomics is a potent tool to dig into the biology of the stallion spermatozoa. The aim of this review is to present an overview of...
Survey-based investigation of sports and leisure horse owners’ approaches to, and expectations of, equine veterinary care.
The Veterinary record    May 29, 2024   Volume 194, Issue 11 e4197 doi: 10.1002/vetr.4197
Elte Y, Wolframm I, van Grevenhof I, Nielen M, van Weeren R.Client satisfaction depends on the balance between expectations and service experience. Previous research identified seven aspects of equine veterinary professional conduct that are important for client satisfaction: quality of care, quality of service, horsemanship, transfer of knowledge, financial aspects, interpersonal skills and professionalism. Methods: By employing a cross-sectional study design through a survey-based investigation, horse owners' initial contact preferences and their perceptions of the importance of various aspects of veterinary care in different scenarios were explored....
Neck pain but not neurologic disease occurs more frequently in horses with transposition of the ventral lamina from C6 to C7.
Journal of the American Veterinary Medical Association    May 29, 2024   1-7 doi: 10.2460/javma.24.04.0230
Henderson CS, Story MR, Nout-Lomas YS.To determine reasons for horses to have neck radiographs performed, the incidence of transposition of the ventral lamina of C6 onto C7 (TC67), and the final diagnoses for all horses. Our hypotheses were to find a similar incidence of TC67, as has been previously reported, and an increased incidence of neck pain and dysfunction in horses with TC67. Methods: 135 horses. Methods: Retrospective observational study. Medical records of 135 horses with cervical vertebral column radiographs between 2020 and 2022 were assessed. Patient signalment, reasons for radiographs, radiographic findings, and dia...
Bilateral stringhalt associated with Hypochaeris radicata in Uruguayan horses.
Toxicon : official journal of the International Society on Toxinology    May 29, 2024   Volume 245 107780 doi: 10.1016/j.toxicon.2024.107780
Machado M, Camacho AL, Coubrough C, R R Queiroz-Machado C, Custodio C, Barros CSL, Riet-Correa F, Menchaca A.We reported thirteen cases of bilateral stringhalt associated with Hypochaeris radicata that occurred in horses in Uruguay during a severe drought in the summer of 2023. All horses were affected chronically and progressively by bilateral hyperflexion of hindlimbs. In two severely affected horses, the main histological lesions included neuronal chromatolysis and axonal spheroids in the ventral gray horn in the lumbar and sacral spinal cord and axonal degeneration and digestion chambers in ventral roots fibers and long peripheral nerves. We suggest that in addition to injuries to peripheral nerv...
Pregnancy and Luteal Responses to Embryo Reinsertion following Embryo Flushing in Donor Mares.
Animals : an open access journal from MDPI    May 29, 2024   Volume 14, Issue 11 doi: 10.3390/ani14111605
Martínez-Boví R, Gaber JTH, Sala-Ayala L, Plaza-Dávila M, Cuervo-Arango J.The effect of embryo reinsertion immediately after embryo flushing was studied. In Experiment 1, eight mares were used during 32 cycles (8 cycles in each group). For the first two groups, inseminated mares were flushed 8 days after ovulation and prostaglandin F2α was not administered: in group EF-ET (embryo flushing and embryo transfer) the embryo was reinserted in the same donor mare, while in the EF group, no further procedure was performed. In the third group (ET), non-inseminated mares (recipients) received a Day 8 embryo. Progesterone concentration was measured before EF/ET and 72 h afte...
Opinions regarding equine veterinarian attire and attributes: results of a horse owner survey.
Journal of the American Veterinary Medical Association    May 29, 2024   Volume 262, Issue 8 1081-1089 doi: 10.2460/javma.24.02.0083
O'Neil EK, Fogle CA, Sheats MK, Love K.To investigate potential equine clients' perceptions of equine veterinarians based on attire. Methods: 763 horse owners/lessees. Methods: Participants were invited to complete a survey shared mainly via equestrian social media pages between August and October 2022.1-3 Survey participants were shown pictures of a male veterinarian and a female veterinarian in 7 outfits ranging from casual to business attire and were asked to score the veterinarian on 7 traits: easygoing attitude, friendliness, compassion, trustworthiness, professionalism, competence, and cost of services. The survey asked which...
Using infrared thermography for the evaluation of road transport thermal homeostasis in athletic horse.
Journal of equine veterinary science    May 28, 2024   Volume 138 105102 doi: 10.1016/j.jevs.2024.105102
Aragona F, Arfuso F, Rizzo M, Fazio F, Acri G, Piccione G, Giannetto C.This study aimed to evaluate changes in body temperature in athletic horses during two different road transport distances. Six Italian Saddle horses were subjected to a 100 and 300 km transport during different times of day (am and pm). Rectal and cutaneous temperatures were recorded before (T0), immediately (following 5 min- T1) and 1 hour (T2) after transport by means of a rectal digital thermometer and a thermal infrared camera (FLIR T440) respectively, for the evaluation of left and right side of four body regions: jugular, shoulder, croup and inner thigh. There were no differences between...
Detection of Equine Parvovirus-Hepatitis Virus and Equine Hepacivirus in Archived Sera from Horses in France and Australia.
Viruses    May 28, 2024   Volume 16, Issue 6 862 doi: 10.3390/v16060862
Fortier C, El-Hage C, Normand C, Hue ES, Sutton G, Marcillaud-Pitel C, Jeffers K, Bamford N, Oden E, Paillot R, Hartley C, Gilkerson J, Pronost S.Reports of newly discovered equine hepatotropic flavi- and parvoviruses have emerged throughout the last decade in many countries, the discovery of which has stimulated a great deal of interest and clinical research. Although commonly detected in horses without signs of disease, equine parvovirus hepatitis (EqPV-H) and equine hepacivirus (EqHV) have been associated with liver disease, including following the administration of contaminated anti-toxin. Our aim was to determine whether EqPV-H and EqHV are present in Australian horses and whether EqPV-H was present in French horses and to examine ...
ECEIM consensus statement on equine kidney disease.
Journal of veterinary internal medicine    May 27, 2024   doi: 10.1111/jvim.17101
van Galen G, Divers TJ, Savage V, Schott HC, Siwinska N.The aim of this consensus statement is to summarize and appraise scientific evidence and combine this with the clinical experience of a panel of experts to optimize recommendations on how to recognize and manage kidney disease in horses.
Approach to Immune-mediated Ocular Diseases.
The Veterinary clinics of North America. Equine practice    May 27, 2024   Volume 40, Issue 2 275-286 doi: 10.1016/j.cveq.2024.04.003
Knickelbein KE, Lassaline ME.Immune-mediated ocular inflammation is a common clinical diagnosis reached for horses with keratitis and uveitis. This diagnosis is made as a diagnosis of exclusion following a thorough effort to rule out an underlying cause for the inflammation, most importantly infectious and neoplastic disease. Practically, response to ophthalmic and systemic anti-inflammatory or immunomodulatory medications is used to support a diagnosis of immune-mediated ocular inflammation; however, such medications are often contraindicated in the face of infection or neoplasia. This article will summarize our current ...
First identification and isolation of equine herpesvirus type 1 in aborted fetal lung tissues of donkeys.
Virology journal    May 27, 2024   Volume 21, Issue 1 117 doi: 10.1186/s12985-024-02390-2
Tong P, Pan J, Dang Y, Yang E, Jia C, Duan R, Tian S, Palidan N, Kuang L, Wang C, Lu G, Xie J.Equine herpesvirus type 1 (EHV-1) is commonly associated with horse abortion. Currently, there are no reported cases of abortion resulting from EHV-1 infection in donkeys. This was the first survey-based study of Chinese donkeys. The presence of EHV-1 was identified by PCR. This survey was conducted in Chabuchar County, North Xinjiang, China, in 2020. A donkey EHV-1 strain (Chabuchar/2020) was successfully isolated in MDBK cells. Seventy-two of 100 donkey sera were able to neutralize the isolated EHV-1. Moreover, the ORF33 sequence of the donkey-origin EHV-1 Chabuchar/2020 strain showed high l...
Operational Radiation Safety Considerations During Equine Superficial Radiation Treatment Using Portable X-Ray Devices.
Health physics    May 26, 2024   Volume 127, Issue 5 625-632 doi: 10.1097/HP.0000000000001841
Singh A, Johnson T, Wotman K, Leary D.Veterinary personnel exposure due to scattered x rays, when present during superficial radiation treatment (SRT), was evaluated. Veterinary personnel presence is needed during SRT to minimize the degree of required aesthesia to horses. Animal treatment was simulated, and exposure rates determined for 50, 70, and 100 kV x rays using eight different SRT applicators. Exposure rates at the surface of a solid water phantom (SWP) phantom ranged from 3.9 mR h-1 to 396 mR h-1 for 50 kV, from 41 mR h-1 to 2,880 mR h-1 for 70 kV, and from 235 mR h-1 to 7,500 mR h-1, for 100 kV, respectively. A horse pha...
First report of ivermectin resistance in cyathostomins (small strongyles) of horses in Argentina.
Veterinary parasitology, regional studies and reports    May 25, 2024   Volume 52 101046 doi: 10.1016/j.vprsr.2024.101046
Cooper LG, Benard BP, Nielsen MK, Caffe G, Arroyo F, Anziani OS.In Argentina, as in the rest of the world, cyathostomins are the most common nematodes parasitizing horses. Control is based almost exclusively on the administration of benzimidazoles, pyrimidines, and macrocyclic lactones. However, intensive use of these drugs is resulting in the development of anthelmintic resistance (AR). For example, AR to benzimidazoles is currently distributed throughout Argentina, while incipient AR to pyrimidines (pyrantel embonate) is appearing in areas where this drug is used. Macrocyclic lactones and especially ivermectin, are by far the most used drugs by the vast ...
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