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Topic:Clinical Findings

Clinical findings in horses encompass a range of observable signs and symptoms identified during veterinary examinations that contribute to diagnosing and managing equine health conditions. These findings can include physical observations, such as changes in behavior, posture, or gait, as well as physiological measurements like heart rate, respiratory rate, and temperature. Diagnostics may also involve laboratory tests, imaging, and other diagnostic procedures to assess organ function and detect abnormalities. Recognizing and interpreting clinical findings are essential components of veterinary practice, aiding in the identification of diseases, monitoring treatment progress, and guiding therapeutic interventions. This page brings together peer-reviewed research studies and scholarly articles that explore the methodologies, interpretations, and implications of clinical findings in the context of equine health care.
Orthodromic Atrioventricular Reentry Bradycardia and Tachycardia Caused by an Accessory Pathway in Horses.
Journal of veterinary internal medicine    July 17, 2025   Volume 39, Issue 4 e70175 doi: 10.1111/jvim.70175
Buschmann E, Easton-Jones C, Van Steenkiste G, De Wilde H, Roberts V, Durando M, Decloedt A, Marr C, van Loon G.Accessory pathways (APs) are muscular bundles directly connecting the atria and ventricles, bypassing the atrioventricular (AV) node-His-Purkinje system. Anterograde conduction along the AP results in ventricular preexcitation. A retrograde conducting AP allows ventriculo-atrial (VA) conduction, creating a reentry circuit that mediates orthodromic atrioventricular reentry tachycardia (OAVRT). This condition is well described in humans and small animals, but has not been reported previously in horses. Objective: Describe clinical and electrocardiographic findings of horses with retrograde AP co...
Detection of Novel Orthobunyavirus Reassortants in Fatal Neurologic Case in Horse and Culicoides Biting Midges, South Africa.
Emerging infectious diseases    June 26, 2025   Volume 31, Issue 7 1455-1459 doi: 10.3201/eid3107.241800
Rakaki ME, van der Walt M, Williams J, Venter M.We detected Shuni virus in horses and ovine fetuses and Shamonda virus in a caprine fetus in South Africa. We identified a Shuni/Shamonda virus reassortant in a horse and Shuni/Caimito, Shamonda/Caimito, and Shamonda/Sango virus reassortants in Culicoides midges. Continued genomic surveillance will be needed to detect orthobunyavirus infections in Africa.
Tracheal collapse rates in Kenyan working cart and pack donkeys.
Equine veterinary journal    June 26, 2025   doi: 10.1111/evj.14545
Mellish M, Burns J, Elce Y, Stull JW.Donkeys (Equus asinus) in East Africa are recognised as working with poorly designed harnesses and carts. The donkey cart used in regions of Africa, specifically Meru County, Kenya, appears to place the cart's weight solely on the donkey's mid-cervical region. The ventral area of the neck is vulnerable to external pressure on the trachea, which is superficially located. Objective: To compare the presence and severity of endoscopic abnormalities in the upper airway and trachea of Meru County working cart donkeys compared to pack donkeys. To determine associations between endoscopic and physical...
Evaluation of use of respiratory physiotherapy in treatment of young foals with pneumonia.
Journal of equine veterinary science    June 25, 2025   105637 doi: 10.1016/j.jevs.2025.105637
Rossi HS, Mykkänen AK, Teppo AM, Junnila JJT, Hyytiäinen HK.Pneumonia is a common condition in young, hospitalized foals, causing accumulation of inflammatory secretions to the airways. In humans, respiratory physiotherapy is commonly used as a supplementary treatment for pneumonia with varying results regarding its efficacy, but the efficacy in foals has not been assessed to date. Objective: This study aimed to evaluate the safety and efficacy of respiratory physiotherapy as a supplementary therapy method for young foals with pneumonia. Methods: A total of 44 foals with pneumonia aged under a month were used. The prospective intervention group receivi...
A Pilot Study on Blood Concentration of β-Amyloid (40 and 42) and Phospho-Tau 181 in Horses.
Veterinary sciences    June 23, 2025   Volume 12, Issue 7 610 doi: 10.3390/vetsci12070610
Gazzano V, Curadi MC, Capsoni S, Baragli P, Kêdzierski W, Cecchi F, Gazzano A.In humans, aging is often accompanied by cognitive decline, as seen in Alzheimer's disease. In contrast, the aging process in horses remains poorly characterized. This study aims to explore the presence of blood-based biomarkers associated with cognitive degeneration in this species. Twenty-three Arabian horses were enrolled, and 5 mL of blood was collected from each to measure serum levels of β-amyloid peptides (Aβ40 and Aβ42) and phosphorylated tau protein (pTau181), both considered reliable indicators of cognitive impairment in other species. Aβ42 was undetectable in all samples, while ...
[Diagnostic imaging of the equine cervical spine and clinical significance of findings – review of literature – Part two: Ultrasonography, myelography, computed tomography, magnetic resonance tomography, and nuclear medicine].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    June 13, 2025   Volume 53, Issue 3 191-196 doi: 10.1055/a-2536-5264
Hellige M, Geburek F.Diagnostic imaging is an important part of the diagnostic approach in equine spinal ataxia especially with the cervical spine being commonly involved. The spinal cord may be affected by a variety of conditions including cervical vertebral malformations, osteoarthritis of the articular process joints or less commonly neoplasia. Advanced imaging techniques such as myelography are more accurate in diagnosing spinal cord compression and may be performed under general anesthesia in neutral, flexed and extended positions of the cervical spine. The use of ultrasound is non-invasive and allows ultraso...
Correction to ‘Prejudicial findings regarding suitability for intended purpose during pre-purchase examinations in a mixed horse population-A retrospective observational study in the United Kingdom’.
Equine veterinary journal    June 12, 2025   doi: 10.1111/evj.14544
No abstract available
Suspected marsh mallow (Malva parviflora) toxicosis in ponies-Case cluster including an asymptomatic survivor.
Australian veterinary journal    June 12, 2025   doi: 10.1111/avj.13455
Bauquier J, Takahashi C, Rosales C, Pitt J.There is limited published information on Malva parviflora toxicosis in horses. Four previously reported cases all resulted in death or euthanasia. The aim of this cluster investigation was to describe historical, clinical and clinicopathological findings of four ponies with suspected M. parviflora toxicosis and compare these to previously reported cases. Historical, clinical and clinicopathological findings were collated. Ponies were grazing pasture of approximately >90% M. parviflora. Pony 1 died rapidly without veterinary examination. Pony 2 was examined for prolonged recumbency attribut...
Computed tomography and nephrotomy in a Warmblood stallion with bilateral nephrolithiasis.
Journal of equine veterinary science    June 10, 2025   Volume 151 105627 doi: 10.1016/j.jevs.2025.105627
Schlote MT, Drozdzewska K, Ehrle A, Lischer C, Gehlen H.This case report describes the use of computed tomography for the diagnosis and surgical planning in a horse with bilateral nephrolithiasis. An adult Warmblood stallion (460 kg) was presented with chronic weight loss, hypercalcemia and azotemia. Ultrasonographic examination identified hyperechoic masses in both kidneys and dilation of the right renal pelvis. A solid mass was evident upon transrectal examination on the left side. Computed tomography (CT) of the caudal abdomen was performed and provided good quality images that facilitated exact determination of the size, position and extent of ...
Clinical Prevalence of Equine Coital Exanthema in a Thoroughbred Covering Station in Türkiye (2021-2024).
Reproduction in domestic animals = Zuchthygiene    June 9, 2025   Volume 60, Issue 6 e70086 doi: 10.1111/rda.70086
Atay YE, Ekinci G, Öztürk AE, Timur MC, Mete A, Altınbay K, Derelli FM, Akar Y, Keleş İ.Equine Coital Exanthema (ECE) is an endemic herpesvirus disease primarily affecting the external genitalia and impairing mating activities in horses. Its extremely contagious nature, latency and subclinical features can result in outbreaks and significant economic losses. Transmission occurs primarily through mating activities; therefore, robust biosecurity measures are crucial in breeding facilities. This study aims to determine the clinical prevalence of ECE among horses in a covering station in Türkiye from 2021 to 2024. It also aims to assess the efficacy of routine PCR implementation wit...
Review of published research on primary dysautonomia of domestic animals.
The Veterinary record    June 7, 2025   e5499 doi: 10.1002/vetr.5499
Harte T, Smith D, Moore J, Wells B.An article published in 1992 by Marion M. Pollin and I.R. Griffiths reviewed the topic of primary dysautonomias of the autonomic nervous system of unidentified origin in multiple domestic species, specifically cats, dogs and horses. Thirty-one years later, we appear no closer to identifying the causal agents of these strikingly similar diseases. This article reviews the similarities and differences in clinical presentation and pathology of dysautonomia in canids, felids, equids, leporids and other less frequently reported species.
Severe urticaria in a horse after consumption of horseweed (Conyza canadensis (L.) Cronquist) – A case study.
Acta veterinaria Hungarica    June 5, 2025   Volume 73, Issue 2 81-85 doi: 10.1556/004.2025.01149
Cserhalmi D, Wermer K.Our paper presents a case study of a Welsh pony mare with grazing-induced severe urticaria. The main clinical signs were eye swelling, depression and extensive urticaria. Physical examination revealed no other abnormalities. Botanical sampling revealed horseweed (Conyza canadensis) as the most abundant species and a potential allergen plant due to sesquiterpene lactones (SQL). Differential diagnosis strongly suggested that the clinical signs were the result of a hypersensitivity reaction to this plant. Former studies brought controversial data about the toxic or allergic potential of horsewee...
Clinical occurrence of trypanosomiasis in Arabian horses from Ahvaz.
Veterinary clinical pathology    June 3, 2025   doi: 10.1111/vcp.70003
Nikvand AA, Jalali SM, Bahrami S, Rahij Torfi H.Trypanosoma evansi (T. evansi) is a hemoprotozoan parasite affecting camels and equids, such as horses, mules, and donkeys, and is known to cause surra disease in these animals. Despite the worldwide distribution of T. evansi infections in equids, surra has not been reported in Arabian horses in Khuzestan Province for over 60 years. In September 2018, a 7-year-old Arabian mare was referred from a 10-horse farm in the suburbs of Ahvaz City. The mare presented with a history of weight loss, poor appetite, and proximity to a camel herd. Physical examination revealed a poor body condition score ...
Western performance horses with fetlock lameness demonstrate radiographic evidence of chronic exercise remodelling.
Equine veterinary journal    May 19, 2025   doi: 10.1111/evj.14514
Solum G, Acutt E, Johnson SA, Zhou T, Contino EK, Donnell JR, Donnell A, Frisbie DD.Pathological changes of the fetlock joint are well documented in Thoroughbreds, but little information is available describing the common radiographic findings in western performance horses with fetlock lameness. Objective: To describe radiographic findings in western performance horses with fetlock lameness. It was hypothesised that the degree of lameness would correlate with the severity of radiographic findings. Methods: Retrospective case series. Methods: Retrospective review (2012-2022) of horses with lameness isolated to the fetlock joint via intra-articular analgesia and corresponding r...
Ventriculophasic response in a horse with atrioventricular block.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    May 17, 2025   Volume 60 46-49 doi: 10.1016/j.jvc.2025.05.005
Liu J, Baumwart R, Kwon S.Ventriculophasic response (VR) in atrioventricular nodal (AVN) block is characterized by a shortening of the sinoatrial cycle length when a QRS complex is interposed between two P waves. This has been well documented in humans and dogs with AVN blocks but not in horses. Herein, we describe a horse with second-degree AVN blocks and constant PR intervals that exhibited 5:3 conduction and suspected VR at rest but less consistently after submaximal exercise. Proposed VR mechanisms include (1) inhibition of the Bezold-Jarisch reflex from reduced end-systolic volume during ventricular contraction; (...
Sinonasal angiofibroma in a horse.
Journal of comparative pathology    May 13, 2025   Volume 219 88-90 doi: 10.1016/j.jcpa.2025.05.003
Schollmeyer M, Liebler-Tenorio EM, Felton C, Kohl S, Ulrich R.A 34-year-old Haflinger gelding presented with a unilateral, expansile, intranasal mass that regrew after partial excision. After euthanasia, a large pedunculated mass that originated from the left caudal maxillary sinus and obliterated the left nasal cavity was seen by radiological and macroscopic examination. Histopathology revealed a poorly cellular, expansile, well-vascularized neoplasm composed of a loosely arranged meshwork of spindle cells and collagen fibres. Spindle cells were immunopositive for alpha-smooth muscle actin and occasionally for vimentin, whereas endothelial cells immunol...
First report on equine papillomavirus type 1 in Arabian horses in Saudi Arabia: Clinical, histopathological, and molecular characterization.
Open veterinary journal    April 30, 2025   Volume 15, Issue 4 1798-1802 doi: 10.5455/OVJ.2025.v15.i4.32
Al-Hammadi MA.Equine papillomavirus type 1 (EcPV-1) causes cutaneous papillomatosis in horses, which is characterized by benign, proliferative epithelial lesions. Despite its global presence, the prevalence and characterization of EcPV-1 in Arabian horses in Saudi Arabia have not been previously reported. Unassigned: This study is the first to identify and comprehensively analyze EcPV-1 in four Arabian horses presenting with multiple raised, verrucous lesions around the muzzle and lips. Unassigned: This study involved clinical examination, skin biopsy collection, histopathological examination, and molecular...
Oral Extraction and Nasal Retrieval of a Fragmented Maxillary Fourth Premolar Tooth in a Horse Using Endoscopic Guidance: A Case Report.
Journal of veterinary dentistry    April 29, 2025   Volume 42, Issue 5 397-406 doi: 10.1177/08987564251334882
Clarysse M, Korsos S, Vlaminck L.This case report presents the removal of the left maxillary fourth premolar tooth (208) which had a chronic complicated crown root fracture in a 9-year-old Warmblood mare. Following a 14-month history of malodorous nasal discharge, clinical and radiographic examination allowed the diagnosis of a comminuted crown root fracture of 208 and oronasal fistula. Some root fragments inaccessible for oral extraction were subsequently removed using a transnasal approach through the existing oronasal fistulous tract using bronchoesophageal forceps under endoscopic guidance. The oronasal fistula was surgic...
Allele Frequencies and Genotypes for the Ryanodine Receptor 1 Variant Causing Malignant Hyperthermia and Fatal Rhabdomyolysis With Hyperthermia in Horses.
Journal of veterinary internal medicine    April 29, 2025   Volume 39, Issue 3 e70081 doi: 10.1111/jvim.70081
Aleman M, McCue M, Bellone RR.Fatal anesthesia-induced malignant hyperthermia (MH) and rhabdomyolysis with hyperthermia documented in Quarter Horses (QH) breeds are caused by a missense variant in the ryanodine receptor 1 gene (RYR1: XP_023505430.1.:p.(R2454G), designated as MH). The reported cases to date have all been heterozygous, and the allele frequency is suspected to be low. Objective: To determine an accurate estimate of MH allele frequency in multiple horse breeds and investigate whether homozygous animals exist in the population. Methods: In total, 159 227 horses from 16 breeds who were either submitted for cli...
Patent Urachus and Associated Comorbidities in 101 Newborn Foals: A Retrospective Study.
Veterinary medicine and science    April 28, 2025   Volume 11, Issue 3 e70379 doi: 10.1002/vms3.70379
Bernick A, Krohn J, Wehrend A.Patent urachus is a common disease in newborn foals. However, despite its frequency, studies investigating symptoms, comorbidities, treatment and prognosis in a large number of affected foals have rarely been conducted. This study aimed to describe the clinical symptoms, laboratory diagnostic findings and prognosis of foals with patent urachus. Data from 101 foals with a patent urachus from 2006 to 2017 were analysed. Patent urachus occurred at a frequency of 7.8% of all foals up to the 14th day of life during the study period. More colts (74.3%) than fillies (25.7%) were affected. In those wi...
Integration of machine learning and viscoelastic testing to improve survival prediction in horses experiencing acute abdominal pain at a veterinary teaching hospital.
Equine veterinary journal    April 24, 2025   doi: 10.1111/evj.14517
Macleod BM, Wilkins PA, McCoy AM, Bishop RC.Viscoelastic coagulation testing (VCT) identifies subclinical disruption of coagulation homeostasis and may improve prognostication, particularly for patients with severe systemic inflammation or shock. Machine learning (ML) algorithms may capture complex relationships between clinical variables better than linear regression (GLM). Objective: To evaluate the utility of ML models incorporating VCT and clinical data to predict survival outcomes in horses with acute abdominal pain. Methods: Retrospective observational cohort study. Methods: VCT (VCM Vet™) was performed on 57 horses with acute a...
Chronic idiopathic myopathy in Icelandic horses: A case series.
Equine veterinary journal    April 24, 2025   Volume 57, Issue 5 1341-1346 doi: 10.1111/evj.14519
Hansen S, Hopster-Iversen C, Berg L, Fjeldborg J, Massey C, Piercy RJ, Carstensen H.Exertional myopathies are recognised as a cause of poor performance in equines. In Icelandic horses presenting reduced performance and/or multi-limb lameness, no specific myopathy has been identified. Objective: To characterise the clinical presentation and histopathological findings in muscle biopsy samples from Icelandic horses demonstrating poor performance. Methods: Case series. Methods: Phenotypic characteristics, clinical examination and diagnoses of 17 Icelandic horses were studied. All horses had a resting serum creatine kinase (CK) and aspartate transaminase activities measured, and C...
Sorghum poisoning in ruminants and horses: a review.
Toxicon : official journal of the International Society on Toxinology    April 24, 2025   Volume 261 108375 doi: 10.1016/j.toxicon.2025.108375
Vasconcelos de Sousa AL, Riet-Correa F, Botelho de Castro M, Machado M.We reviewed the history, epidemiology, clinical signs, pathology, pathogenesis, treatment, control, and prophylaxis of Sorghum poisoning in livestock. Economic losses in the livestock industry associated with sorghum have been reported since the 19th century. Hyperacute/acute poisoning associated with cyanide (HCN) or nitrate/nitrite frequently occurs in ruminants that consume high quantities of growth and regrowth sorghum after drought, followed by rainfall, respectively. Chronic cystitis-ataxia syndrome primarily affects horses after weeks of grazing on sorghum pastures, while congenital art...
Management of an Equine Herpesvirus-1 Outbreak During a Multi-Week Equestrian Event.
Viruses    April 24, 2025   Volume 17, Issue 5 doi: 10.3390/v17050608
Pusterla N, Lawton K, Barnum S, Flynn K, Hankin S, Runk D, Mendonsa E, Doherty T.The present study reports on the management of an EHV-1 outbreak at a large, multi-week equestrian event with ongoing showing. Within a 48 h period, 8 horses out of a cohort of 38 horses from the same trainer displayed elevated rectal temperatures ranging from 38.4 to 39.0 °C. Initial testing using a point-of-care PCR assay detected EHV-1 in 2/8 horses, with the results being confirmed at a later time by qPCR. As a precautionary measure and because of the inability to isolate the entire at-risk population, the 38 horses were relocated to an equine facility outside the equestrian event for dai...
Motor pathway evaluation by transcranial magnetic stimulation in Swedish horses with acquired equine polyneuropathy.
Equine veterinary journal    April 21, 2025   doi: 10.1111/evj.14506
May A, Hanche-Olsen S, Goehring LS, Matiasek K, Jäderlund KH, Zablotski Y, Gröndahl G.Acquired equine polyneuropathy in Nordic horses (AEP) is the most prevalent equine polyneuropathy in Norway, Sweden, and Finland and is characterised by pelvic limb knuckling due to metatarsophalangeal extension dysfunction. Objective: To evaluate the function of descending motor pathways in AEP using transcranial magnetic stimulation (TMS). Methods: An analytical, observational cohort design. Methods: Clinical findings and TMS results of 20 horses from an AEP outbreak in Sweden were evaluated at 5-month intervals. Latency time (LT) in milliseconds (ms) between coil discharge and onset of musc...
[Guttural pouch mycosis in a warmblood foal – Occlusion of the internal carotid artery using transendoscopic clip application].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    April 15, 2025   Volume 53, Issue 2 132-137 doi: 10.1055/a-2519-7361
Himmele M, Engl JPM, Schwarz BC.The present report describes an 8-week-old warmblood foal presented following two episodes of epistaxis. The foal had a history of an umbilical infection, which had been treated with antibiotics when it was 8 days old. Four days before admission the filly showed severe, self-limiting epistaxis. The second hemorrhage occurred on the day of admission. The foal was lethargic and the remainder of the clinical examination unremarkable. A latero-lateral radiograph of the head revealed a fluid line within the guttural pouch. Endoscopy showed large amounts of blood within the pharynx and the upper thi...
Correction: Clinical features and treatment response to differentiate idiopathic peritonitis from non‑strangulating intestinal infarction of the pelvic flexure associated with Strongylus Vulgaris infection in the horse.
BMC veterinary research    April 14, 2025   Volume 21, Issue 1 265 doi: 10.1186/s12917-024-04388-y
Hedberg-Alm Y, Tydén E, Tamminen LM, Lindström L, Anlén K, Svensson M, Riihimäki M.No abstract available
Haemaphysalis longicornis ticks are unable to transstadially transmit Theileria haneyi to horses.
Frontiers in veterinary science    April 2, 2025   Volume 12 1572944 doi: 10.3389/fvets.2025.1572944
Poh KC, Oyen K, Onzere CK, Kappmeyer LS, Bastos RG.The recent discovery of , a tick-borne hemoparasite that causes mild clinical signs of equine piroplasmosis, has added complexity to the diagnosis of this reportable disease, which is prevalent among equids globally. Knowledge gaps regarding competent tick vectors that can transmit and the recent outbreak of in the US has prompted us to conduct this study. Our objective was to investigate whether can transstadially transmit to horses. Unassigned: larvae (0.5 g) and nymphs ( = 500) were fed on a splenectomized -infected horse for parasite acquisition. During the tick feeding period, ...
Equestrian Trauma in an Urban Environment: A Retrospective Analysis in a Level I Trauma Center.
Cureus    April 2, 2025   Volume 17, Issue 4 e81609 doi: 10.7759/cureus.81609
Swezey E, Szydziak E, Angus LDG, Mehta V, Cardozo-Stolberg S.Equestrian trauma is recognized as a high-risk injury mechanism with the potential for significant morbidity and mortality. Although horse-related injuries are more frequently seen in a rural environment, they can also occur in urban settings. Urban physicians should be mindful of these potential cases. Methods: A retrospective review was performed on all patients treated at Nassau University Medical Center, East Meadow, New York, for equestrian-related trauma from January 1, 2000, to December 31, 2024. Results: Twenty-nine equestrian trauma patients ages 10-70 were included, with injuries ob...
Treatment of Iris Hypoplasia Using Semiconductor Diode Laser in the Horse Under Standing Sedation.
Case reports in veterinary medicine    March 24, 2025   Volume 2025 4021047 doi: 10.1155/crve/4021047
Hefner EM, Stoppini R, McMullen RJ. This study is aimed at describing two unique case presentations of iris hypoplasia and the use of semiconductor diode laser for treatment in the horse. One 20-year-old American Quarter Horse gelding and one 11-year-old pony mare were studied. The presenting clinical signs, surgical technique, and postoperative results for two cases of iris hypoplasia treated with diode laser are described. Immediate postoperative complications-postoperative ocular hypertension (POH), corneal edema, and epithelial bullae-were possible anticipated effects but were controlled with topical medications in the fi...