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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Equine induced pluripotent stem cells or how to turn skin cells into neurons: horse tissues a la carte?
Equine veterinary journal    August 8, 2014   Volume 46, Issue 5 534-537 doi: 10.1111/evj.12300
Donadeu FX.No abstract available
Science-in-brief: Equine laminitis research: milestones and goals.
Equine veterinary journal    August 8, 2014   Volume 46, Issue 5 529-533 doi: 10.1111/evj.12301
Orsini JA.No abstract available
Breeding for speed.
Science (New York, N.Y.)    August 7, 2014   Volume 345, Issue 6197 632 doi: 10.1126/science.345.6197.632-a
Roberts RM.No abstract available
‘Attila the Hen’ and Hendra research.
Australian veterinary journal    August 7, 2014   Volume 92, Issue 7 N8 
Balzer M.No abstract available
Gastrointestinal ultrasonography of normal Standardbred neonates and frequency of asymptomatic intussusceptions.
Journal of veterinary internal medicine    August 7, 2014   Volume 28, Issue 5 1580-1586 doi: 10.1111/jvim.12413
Abraham M, Reef VB, Sweeney RW, Navas de Solís C.Ultrasonographic appearance of the gastrointestinal (GI) tract of equine neonates has not been completely described. Objective: To describe (1) sonographic characteristics of the GI segments in normal nonsedated equine neonates, (2) intra- and interobserver variation in wall thickness, and (3) the sonographic appearance of asymptomatic intussusceptions, and (4) to compare age and sonographic findings of foals with and without asymptomatic intussusceptions. Methods: Eighteen healthy Standardbred foals ≤5 days of age. Methods: Prospective, cross-sectional blinded study. Gastrointestinal sonogr...
Is the left forelimb preference indicative of a stressful situation in horses?
Behavioural processes    August 7, 2014   Volume 107 61-67 doi: 10.1016/j.beproc.2014.07.018
Siniscalchi M, Padalino B, Lusito R, Quaranta A.Evidence for behavioural and brain lateralisation is now widespread among the animal kingdom; lateralisation of limb use (pawedness) occurs in several mammals including both feral and domestic horses. We investigated limb preferences in 14 Quarter Horse during different motor tasks (walking, stepping on and off a step, truck loading and unloading). Population lateralisation was observed in two tasks: horses preferentially used their left forelimb during truck loading and stepping off a step. The results also revealed that horses showed higher scores for anxious behaviours during truck loading ...
Comparison of respiratory function during TIVA (romifidine, ketamine, midazolam) and isoflurane anaesthesia in spontaneously breathing ponies Part I: blood gas analysis and cardiorespiratory variables.
Veterinary anaesthesia and analgesia    August 7, 2014   Volume 41, Issue 6 583-591 doi: 10.1111/vaa.12167
Steblaj B, Schauvliege S, Pavlidou K, Gasthuys F, Savvas I, Duchateau L, Kowalczyk L, Moens Y.To compare pulmonary function and gas exchange in ponies during maintenance of anaesthesia with isoflurane or by a total intravenous anaesthesia (TIVA) technique. Methods: Experimental, cross-over study. Methods: Six healthy ponies weighing mean 286 (range 233-388) ± SD 61 kg, age 13 (9-16) ± 3 years. Methods: The ponies were anaesthetized twice, a minimum of two weeks apart. Following sedation with romifidine [80 μg kg(-1) intravenously (IV)], anaesthesia was induced IV with midazolam (0.06 mg kg(-1)) and ketamine (2.5 mg kg(-1), then maintained either with inhaled isoflurane (Fe'Iso = 1.1...
The eyes and ears are visual indicators of attention in domestic horses.
Current biology : CB    August 6, 2014   Volume 24, Issue 15 R677-R679 doi: 10.1016/j.cub.2014.06.023
Wathan J, McComb K.Sensitivity to the attentional states of others has adaptive advantages, and in social animals, attending to others is important for predator detection, as well as a pre-requisite for normal social functioning and more complex socio-cognitive abilities. Despite widespread interest in how social species perceive attention in others, studies of non-human animals have been inconclusive about the detailed cues involved. Previous work has focused on head and eye direction, overlooking the fact that many mammals have obvious and mobile ears that could act as a visual cue to attention. Here we report...
Serum neutralization assay can efficiently replace plaque reduction neutralization test for detection and quantitation of West Nile virus antibodies in human and animal serum samples.
Clinical and vaccine immunology : CVI    August 6, 2014   Volume 21, Issue 10 1460-1462 doi: 10.1128/CVI.00426-14
Di Gennaro A, Lorusso A, Casaccia C, Conte A, Monaco F, Savini G.A serum neutralization assay (SN) was compared with the official plaque reduction neutralization test for the quantitation of West Nile virus antibodies. A total of 1,348 samples from equid sera and 38 from human sera were tested by these two methods. Statistically significant differences were not observed, thus supporting the use of SN for routine purposes.
[Drug resistance found in horse parasites against anthelmintics].
Tijdschrift voor diergeneeskunde    August 6, 2014   Volume 139, Issue 7 36-37 
Haneveld JK.No abstract available
Comparison of the effect of two doses of omeprazole on the squamous gastric mucosa in thoroughbred racehorses.
The Veterinary record    August 5, 2014   Volume 175, Issue 10 249 doi: 10.1136/vr.102622
Sykes BW, Sykes K, Hallowell GD.No abstract available
Nestin expression in mesenchymal stromal cells: regulation by hypoxia and osteogenesis.
BMC veterinary research    August 5, 2014   Volume 10 173 doi: 10.1186/s12917-014-0173-z
Wong A, Ghassemi E, Yellowley CE.The intermediate filament protein nestin is used as a marker for neural stem cells, and its expression is inversely correlated with cellular differentiation. More recently, nestin expression has also been described in other cell types including multipotential mesenchymal stromal cells (MSCs). In this study, we examined the expression of nestin in equine, canine and human bone marrow-derived MSCs undergoing osteogenic differentiation, to determine whether nestin levels were attenuated as the cells acquired a more mature phenotype. In addition, the expression of nestin may be under the influence...
Prevalence of different head-neck positions in horses shown at dressage competitions and their relation to conflict behaviour and performance marks.
PloS one    August 4, 2014   Volume 9, Issue 8 e103140 doi: 10.1371/journal.pone.0103140
Kienapfel K, Link Y, König V Borstel U.Much controversy exists among riders, and in particular among those practicing dressage, regarding what can be considered an "appropriate" Head-Neck-Position (HNP). The objective was to assess the prevalence of different HNPs in the field, the behavioural reactions of horses during warm-up and competition rides in relation to HNP and the relation between HNP and marks achieved in the competition. Horses (n = 171) were selected during dressage competitions according to their HNP (3 categories based on the degree of flexion), and their behaviour was recorded during 3 minutes each of riding i...
Multipotency of equine mesenchymal stem cells derived from synovial fluid.
Veterinary journal (London, England : 1997)    August 4, 2014   Volume 202, Issue 1 53-61 doi: 10.1016/j.tvjl.2014.07.029
Murata D, Miyakoshi D, Hatazoe T, Miura N, Tokunaga S, Fujiki M, Nakayama K, Misumi K.Cartilage regeneration with cell therapy following arthroscopic surgery could be used in racehorses with intra-articular fractures (IAF) and osteochondritis dissecans (OCD). The aims of this study were to investigate the origin and multipotency of stromal cells in the synovial fluid (SF) of horses with intra-articular injury and synovitis, and to provide a new strategy for regeneration of lost articular cartilage. Mesenchymal stromal cells were isolated from SF of horses with IAF and OCD. Multipotency was analysed by RT-PCR for specific mRNAs and staining for production of specific extracellul...
Morphologic and morphometric features of the calcaneal insertions of the superficial digital flexor tendon in the horse.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    August 4, 2014   Volume 27, Issue 5 366-371 doi: 10.3415/VCOT-14-03-0050
Barker WH, Wright IM.Accurate description of the calcaneal insertions of the superficial digital flexor tendon (SDFT) is lacking and inconsistent. The aim of this study was to undertake morphologic and morphometic evaluations of these structures to assist in elucidating their functional and pathogenic roles in displacement of the SDFT from the calcaneal tuber. Methods: Dissections were performed on 10 normal cadaveric hindlimbs. The anatomy was photographed to allow measurements at repeatable locations and differences in SDFT dimensions at the various locations were compared using a paired student t-test. Results:...
Bacteriostatic effect of equine pure platelet-rich plasma and other blood products against methicillin-sensitive Staphylococcus aureus. An in vitro study.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    August 4, 2014   Volume 27, Issue 5 372-378 doi: 10.3415/VCOT-14-04-0054
López C, Carmona JU, Giraldo CE, Alvarez ME.1) To evaluate the bacteriostatic in vitro effect of pure platelet-rich plasma (P-PRP), pure platelet-rich gel (P-PRG), leukocyte-poor gel (LPG), platelet-poor plasma (PPP), and heat inactivated plasma (IP) against methicillin-sensitive Staphylococcus aureus (MSSA) over a period of 24 hours. 2) To determine the degradation of platelet factor-4 (PF-4), transforming growth factor beta 1 (TGF-β1), and platelet-derived growth factor isoform BB (PDGF-BB) in these equine blood components. 3) To establish correlations between platelet and leukocyte counts, PF-4 concentrations, and MSSA growth. Metho...
Effects of oral powder electrolyte administration on packed cell volume, plasma chemistry parameters, and incidence of colic in horses participating in a 6-day 162-km trail ride.
The Canadian veterinary journal = La revue veterinaire canadienne    August 2, 2014   Volume 55, Issue 8 765-771 
Walker WT, Callan RJ, Hill AE, Tisher KB.This study evaluated the effects of administering oral powder electrolytes on packed cell volume (PCV), plasma chemistry parameters, and incidence of colic in horses participating on a 6-day 162-km trail ride in which water was not offered ad libitum. Twenty-three horses received grain with powder electrolytes daily while 19 control horses received grain only. Horses were ridden approximately 32 km a day at a walk or trot. Packed cell volume and plasma chemistry parameters were analyzed daily. Episodes of colic were diagnosed and treated by a veterinarian unaware of treatment group allocation....
Equine disease surveillance: quarterly summary.
The Veterinary record    August 2, 2014   Volume 175, Issue 5 111-114 doi: 10.1136/vr.g4585
No abstract available
[Equine infectious anemia–a review].
Berliner und Munchener tierarztliche Wochenschrift    August 2, 2014   Volume 127, Issue 7-8 297-300 
Haas L.This article combines essential facts of equine infectious anemia. Beside etiology and epidemiology, emphasis is put on the clinical course and laboratory diagnosis. Finally, control measures and prophylactic issues are discussed.
End-to-Side Versus Side-to-Side Jejunocecostomy in Horses: A Retrospective Analysis of 150 Cases.
Veterinary surgery : VS    August 2, 2014   Volume 44, Issue 4 527-533 doi: 10.1111/j.1532-950X.2014.12256.x
Brown JA, Holcombe SJ, Southwood LL, Byron CR, Embertson RM, Hauptmann JG.To determine factors associated with postoperative reflux, postoperative colic, repeat celiotomy, and survival in horses after end-to-side (E2S) or side-to-side (S2S) jejunocecostomy. Methods: Retrospective, multicenter study. Methods: Horses (n = 150). Methods: Admissions, intra- and postoperative data were collected from medical records of horses that had E2S or S2S jejunocecostomy. Descriptive statistics were calculated and data were analyzed using parametric and nonparametric tests, linear and multivariate logistic regression with significance set at P < .05. Kaplan-Meier estima...
Three-week summer period prevalence of Clostridium difficile in farm animals in a temperate region of the United States (Ohio).
The Canadian veterinary journal = La revue veterinaire canadienne    August 2, 2014   Volume 55, Issue 8 786-789 
Rodriguez-Palacios A, Barman T, LeJeune JT.The cross-sectional (period) prevalence of Clostridium difficile in 875 farm animals from 29 commercial operations during the summer of 2008 in Ohio, USA was quantified. Compared to an external referent population of intensively managed race horses (12.7%), intensively managed commercially mature food animals (poultry, cattle, swine; < 0.6%) were infrequent shedders of C. difficile (P < 0.00001) during the warmest weeks of 2008. La prévalence par période de chez 875 animaux de ferme provenant de 29 exploitations commerciales durant l’été de 2008 en Ohio, aux États-Unis, est quan...
Focus on: vaccination against equine grass sickness.
The Veterinary record    August 2, 2014   Volume 175, Issue 5 114-115 doi: 10.1136/vr.g4684
Ireland J.Jo Ireland of the Animal Health Trust describes a new field trial of a potential vaccine against equine grass sickness.
Clinical use of computed tomography and surface markers to assist internal fixation within the equine hoof.
Veterinary surgery : VS    August 2, 2014   Volume 44, Issue 2 214-222 doi: 10.1111/j.1532-950X.2014.12253.x
Gasiorowski JC, Richardson DW.To describe clinical use of computed tomography (CT) and hoof surface markers to facilitate internal fixation within the confines of the hoof wall. Methods: Retrospective case series. Methods: Horses (n = 16) that had CT-guided internal fixation of the distal phalanx (DP) or distal sesamoid bone (DSB). Methods: Drill bit entry point and direction were planned from CT image series performed on hooves with grids of barium paste dots at proposed entry and projected exit sites. Post-implantation CT images were obtained to check screw position and length as well as fracture reduction. Imaging, ...
Gene expression of matrix metalloproteinases and LH receptors in mare follicular development.
Theriogenology    August 1, 2014   Volume 82, Issue 8 1131-1136 doi: 10.1016/j.theriogenology.2014.07.033
Bastos HB, Kretzmann NA, Santos GO, Esmeraldino AT, Rechsteiner SF, Mattos RC, Neves AP.The period from the emergence of a dominant follicle until its formation requires tissue remodeling. Enzymes promoting collagen lysis, such as matrix metalloproteinases (MMPs), are fundamental for the process of extracellular matrix remodeling, which allows changes in ovarian tissue architecture during follicular growth. It has been suggested that the production of these enzymes may be affected by the rise in circulating concentrations of LH, which acts on the ovarian surface epithelium (OSE). The aim of this study was to determine the expression of MMP-1, MMP-2, and LH receptor (LHR) in the o...
Endogenous concentrations, pharmacokinetics, and selected pharmacodynamic effects of a single dose of exogenous GABA in horses.
Journal of veterinary pharmacology and therapeutics    August 1, 2014   Volume 38, Issue 2 113-122 doi: 10.1111/jvp.12146
Knych HK, Steinmetz SJ, McKemie DS.The anti-anxiety and calming effects following activation of the GABA receptor have been exploited in performance horses by administering products containing GABA. The primary goal of the study reported here was to describe endogenous concentrations of GABA in horses and the pharmacokinetics, selected pharmacodynamic effects, and CSF concentrations following administration of a GABA-containing product. The mean (±SD) endogenous GABA level was 36.4 ± 12.5 ng/mL (n = 147). Sixteen of these horses received a single intravenous and oral dose of GABA (1650 mg). Blood, urine, and cerebrospin...
Genetic parameters for earnings in Quarter Horse.
Genetics and molecular research : GMR    August 1, 2014   Volume 13, Issue 3 5840-5848 doi: 10.4238/2014.August.1.2
Silva AP, Curi RA, Langlois B, Silva JA.In this study, we estimated the heritability (h(2)) of earnings in the Quarter Horse in order to evaluate the inclusion of this trait in breeding programs. Records from 14,754 races of 2443 horses from 1978-2009 were provided by Sorocaba Hippodrome, São Paulo, Brazil. All ancestors of the registered horses were included in the pedigree file until the 4th generation. Log-transformed performance measures (LPM) were analyzed for animals aged 2, 3, and 4 years and during their entire career. The h(2) estimates were obtained using a multi-trait model and Gibbs sampling that included the effects of...
Pituitary pars intermedia dysfunction does not necessarily impair insulin sensitivity in old horses.
Domestic animal endocrinology    August 1, 2014   Volume 50 14-25 doi: 10.1016/j.domaniend.2014.07.003
Mastro LM, Adams AA, Urschel KL.Equine pituitary pars intermedia dysfunction (PPID) has been associated with reduced insulin sensitivity in comparison with younger adult horses; however, the difference in insulin sensitivity between horses with PPID and aged-matched controls has not been well characterized. The objective of the study was to determine if aged horses with PPID had reduced insulin sensitivity and alterations in the insulin-mediated signaling pathways in the skeletal muscle when compared with healthy aged horses. Isoglycemic hyperinsulinemic clamp procedures were conducted in 12 horses that were classified as ei...
Correlation between dichromatic colour vision and jumping performance in horses.
Veterinary journal (London, England : 1997)    August 1, 2014   Volume 202, Issue 1 166-171 doi: 10.1016/j.tvjl.2014.07.016
Spaas J, Helsen WF, Adriaenssens M, Broeckx S, Duchateau L, Spaas JH.There is general agreement that horses have dichromatic colour vision with similar capabilities to human beings with red-green colour deficiencies. However, whether colour perception has an impact on equine jumping performance and how pronounced the colour stimulus might be for a horse is unknown. The present study investigated the relationship between the colour of the fences (blue or green) and the show jumping performance of 20 horses ridden by two riders using an indoor and outdoor set of green and blue fences. In the indoor arena, significantly more touches and faults were made on blue fe...
Histomorphometric parameters and fractal complexity of the equine placenta from healthy and sick foals.
Theriogenology    August 1, 2014   Volume 82, Issue 8 1106-1112 doi: 10.1016/j.theriogenology.2014.07.036
Bianco C, Pirrone A, Boldini S, Sarli G, Castagnetti C.Computer-based digital image analysis of tissue samples shows promise both to reduce the subjectivity of traditional manual tissue assessments and potentially to shorten the time required to analyze each sample. The present study used digital image analysis to investigate the histomorphometric parameters and fractal complexity of the equine placenta from healthy and sick foals. We hypothesized that the placentas of sick foals could have a different growth pattern and complexity that could be objectively estimated by their fractal dimension (FD). Fourteen placentas from 30 mares were selected i...
The DMRT3 ‘Gait keeper’ mutation affects performance of Nordic and Standardbred trotters.
Journal of animal science    August 1, 2014   Volume 92, Issue 10 4279-4286 doi: 10.2527/jas.2014-7803
Jäderkvist K, Andersson LS, Johansson AM, Árnason T, Mikko S, Eriksson S, Andersson L, Lindgren G.In a previous study it was shown that a nonsense mutation in the DMRT3 gene alters the pattern of locomotion in horses and that this mutation has a strong positive impact on trotting performance of Standardbreds. One aim of this study was to test if racing performance and trotting technique in the Nordic (Coldblood) trotters are also influenced by the DMRT3 genotype. Another aim was to further investigate the effect of the mutation on performance in Standardbreds, by using a within-family analysis and genotype-phenotype correlations in a larger horse material than in the previous study. We gen...