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Topic:Evidence-Based Medicine

Evidence-Based Medicine (EBM) in horses involves the systematic use of current, peer-reviewed research and clinical expertise to make informed decisions about equine healthcare. EBM aims to integrate the best available scientific data with practical knowledge to optimize treatment outcomes for horses. This approach includes the assessment and application of research findings to guide clinical practices, diagnostic procedures, and therapeutic interventions. By utilizing evidence-based methodologies, veterinarians and equine health professionals can improve the accuracy of diagnoses and the effectiveness of treatments. This page compiles a collection of peer-reviewed research studies and scholarly articles that explore the principles, application, and impact of Evidence-Based Medicine in the field of equine health.
Analgesic Efficacy of Non-Steroidal Anti-Inflammatory Drug Therapy in Horses with Abdominal Pain: A Systematic Review.
Animals : an open access journal from MDPI    November 8, 2023   Volume 13, Issue 22 doi: 10.3390/ani13223447
Citarella G, Heitzmann V, Ranninger E, Bettschart-Wolfensberger R.This systematic review aimed to identify the evidence concerning the analgesic efficacy of non-steroidal anti-inflammatory drugs to treat abdominal pain in horses, and to establish whether one non-steroidal anti-inflammatory drug could provide better analgesia compared to others. This systematic review was conducted following the "Systematic Review Protocol for Animal Intervention Studies". Research published between 1985 and the end of May 2023 was searched, using three databases, namely, PubMed, Embase, and Scopus, using the words equine OR horse AND colic OR abdominal pain AND non-steroidal...
Negative-Pressure Wound Therapy (NPWT) in Horses: A Scoping Review.
Veterinary sciences    August 6, 2023   Volume 10, Issue 8 doi: 10.3390/vetsci10080507
Cantatore F, Pagliara E, Marcatili M, Bertuglia A.Obtaining a healthy wound environment that is conductive to healing in horses can be challenging. Negative-pressure wound therapy (NPWT) has been employed in humans to enhance wound healing for decades. The existing evidence for the effectiveness of NPWT remains uncertain in equine medicine. The aim of this review is to investigate NPWT applications and benefits in horses. A scoping review was performed according to the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines for scoping reviews on three databases (PubMed, Web of Science-Thompson Reuters, and Wiley...
The use of radiofrequency in equine orthopedic surgery.
Journal of the American Veterinary Medical Association    April 26, 2023   Volume 261, Issue 8 1208-1215 doi: 10.2460/javma.23.01.0034
Barton CK, Goodrich LR.The use of radiofrequency energy (RFE) has become increasingly popular in equine orthopedic surgery in recent years, particularly for the debridement of cartilage lesions and soft tissue resection. However, despite considerable advancements in the technology, the safety and efficacy of RFE have continued to be questioned. While studies investigating the use of RFE for chondroplasty in the equine population are lacking, there is an abundance of research studies in the human literature assessing its effect on healthy chondrocytes, and researchers are seeking to develop guidelines to minimize col...
Treatment of equine sarcoids: A systematic review.
Equine veterinary journal    March 14, 2023   doi: 10.1111/evj.13935
Offer KS, Dixon CE, Sutton DGM.The sarcoid is the most common equine cutaneous neoplasm. Evidence-based treatment of this condition is often lacking, and selection of treatment modality based on clinical experience or anecdotal evidence. Objective: To assess the quality of the currently available best evidence regarding the treatment of the equine sarcoid. Methods: Systematic review. Methods: In compliance with PRISMA guidelines, literature searches were performed in PUBMED, Web of Science, CAB Abstracts, EMBASE (Ovid) and Scopus in April 2021. Included papers were required to describe an interventional study examining sarc...
Equine influenza bi-annual boosters: What does the evidence tell us?
Equine veterinary journal    November 16, 2022   Volume 55, Issue 1 147-152 doi: 10.1111/evj.13898
Colgate VA, Newton JR.No abstract available
Integrative Philosophy: Case Management.
The Veterinary clinics of North America. Equine practice    October 13, 2022   Volume 38, Issue 3 455-461 doi: 10.1016/j.cveq.2022.06.004
Adair S.This article serves as an introduction into integrative case management as it applies to the horse's mental health, pain management, and tissue healing. The integrative philosophy pertains to the combination of conventional Western medicine and complementary and alternative therapies to provide the best patient care possible using currently available evidence. The goal is to improve the health of the patient in a more holistic manner.
Study design synopsis: Evidence syntheses-What are they and why do we need them?
Equine veterinary journal    October 6, 2022   Volume 54, Issue 6 1011-1012 doi: 10.1111/evj.13872
Freeman SL.No abstract available
Equine sport must ‘follow the evidence base’.
The Veterinary record    January 22, 2022   Volume 190, Issue 2 60 doi: 10.1002/vetr.1399
Gray A.No abstract available
Impact of hippotherapy on the life habits of children with disabilities: a systematic review.
Disability and rehabilitation    January 19, 2022   Volume 44, Issue 26 8161-8175 doi: 10.1080/09638288.2021.2012847
Potvin-Bélanger A, Vincent C, Freeman A, Flamand VH.The aim was to document the effects of hippotherapy on the 12 life habits of children with various disabilities. A systematic review using PRISMA guidelines was conducted to identify relevant studies. Five databases were consulted. Inclusion criteria were: 2-to-18 years old; therapy provided by a PT, OT or SLP/SLT; variables relevant to life habits as defined by the Human Development Model - Disability Creation Process. Quality was analyzed using a quantitative studies critical review form developed by the McMaster University Occupational Therapy Evidence-Based Practice Research Group. Level...
An Evaluation of Current Preventative Measures Used in Equine Practice to Maintain Distal Forelimb Functionality: A Mini Review.
Frontiers in veterinary science    November 2, 2021   Volume 8 758970 doi: 10.3389/fvets.2021.758970
Clarke EJ, Gillen A, Turlo A, Peffers MJ.Horses are used in a variety of equestrian disciplines predisposing them to musculoskeletal injury or disease including osteoarthritis and tendinopathy. As a result, a number of preventative measures are used within equine medicine and husbandry, ranging from therapeutic shoeing to the use of nutraceuticals. Despite their popularity and routine use evidence base and clinical outcomes are variable, bringing into question the efficacy of these prophylactic measures. In recent years a small number of studies have been performed examining the effect of specific strategies in order to quantify the ...
Animal-Assisted Interventions for Autism Spectrum Disorder: A Systematic Review of the Literature from 2016 to 2020.
Review journal of autism and developmental disorders    September 30, 2021   Volume 10, Issue 2 255-280 doi: 10.1007/s40489-021-00291-6
Nieforth LO, Schwichtenberg AJ, O'Haire ME.In the last five years, the literature on animal-assisted intervention (AAI) for Autism Spectrum Disorder (ASD) has doubled in size from 42 studies prior to 2015 to 85 studies (cumulative total assessed in 2020). Horses remain the most commonly researched animal for AAI, followed by dogs. The most commonly researched outcome was social interaction, across 21 studies. Though the quantity of studies has increased, issues with methodological rigor remain. Results highlight the need for a continued focus on methodological rigor as well as refining the structure of animal-assisted interventions, ad...
Recovery after General Anaesthesia in Adult Horses: A Structured Summary of the Literature.
Animals : an open access journal from MDPI    June 14, 2021   Volume 11, Issue 6 doi: 10.3390/ani11061777
Gozalo-Marcilla M, Ringer SK.Recovery remains the most dangerous phase of general anaesthesia in horses. The objective of this publication was to perform a structured literature review including levels of evidence (LoE) of each study with the keywords "recovery anaesthesia horse", entered at once, in the search browsers PubMed and Web of Science. The two authors independently evaluated each candidate article. A final list with 444 articles was obtained on 5 April 2021, classified as: 41 "narrative reviews/expert opinions", 16 "retrospective outcome studies", 5 "surveys", 59 "premedication/sedation and induction drugs", 27...
Study design synopsis: Observational study design in equine research.
Equine veterinary journal    March 14, 2021   Volume 53, Issue 4 638-644 doi: 10.1111/evj.13427
Lawson A, Pinchbeck G.When planning to conduct research, thorough consideration of the study design is essential to enable valid results and purposeful conclusions. A good study design will provide a strong basis for robust conclusions that can contribute to the evidence base. Conversely, a poor study design may unintentionally lead to invalid conclusions with inappropriate claims of the clinical importance. The purpose of this article is to review important aspects of observational study design, with an emphasis on observational clinical research. The value of an observational study can be manifold and the benefit...
The Effectiveness of Hippotherapy to Recover Gross Motor Function in Children with Cerebral Palsy: A Systematic Review and Meta-Analysis.
Children (Basel, Switzerland)    August 19, 2020   Volume 7, Issue 9 106 doi: 10.3390/children7090106
Guindos-Sanchez L, Lucena-Anton D, Moral-Munoz JA, Salazar A, Carmona-Barrientos I.Cerebral palsy (CP) is a permanent disorder of the posture and movement, which can result in impairments of gross motor function, among others. Hippotherapy (HPT) is an emerging intervention to promote motor recovery in patients with neurological disorders, providing a smooth, precise, rhythmic, and repetitive pattern of movement to the patient. The main objective of this systematic review and meta-analysis of randomized controlled clinical trials was to analyze the effectiveness of HPT interventions on gross motor function in subjects with CP. The following databases were searched in May 2019...
Conflict Between Direct Experience and Research-Based Evidence Is a Key Challenge to Evidence-Based Respiratory Medicine on British Racing Yards.
Frontiers in veterinary science    May 27, 2020   Volume 7 266 doi: 10.3389/fvets.2020.00266
Kinnison T, Cardwell JM.Inflammatory airway disease (IAD) is a commonly diagnosed but variably defined syndrome of equine lower airway inflammation. The most recent American College of Veterinary Internal Medicine (ACVIM) consensus statement, informed by research evidence, recommends a case definition based on clinical signs (poor performance or occasional coughing of at least 3 weeks duration), increased endoscopically-visible tracheal mucus, and bronchoalveolar lavage cytology, and proposes that the condition should be termed 'mild-moderate equine asthma' (mEA). In British Thoroughbred racehorses, research to date ...
Letter to the Editor: Evidence-based farriery – does it exist?
Equine veterinary journal    November 2, 2018   Volume 51, Issue 1 136-137 doi: 10.1111/evj.13023
Coughlan NE, Cuthbert C, O Sullivan C, McSweeney D.No abstract available
Assessment of systematic reviews and meta-analyses available for bovine and equine veterinarians and quality of abstract reporting: A scoping review.
Preventive veterinary medicine    October 23, 2018   Volume 161 50-59 doi: 10.1016/j.prevetmed.2018.10.011
Buczinski S, Ferraro S, Vandeweerd JM.Evidence-based medicine (EBM) is used in various areas including veterinary medicine. The assessment of the quality of systematic review and meta-analyses (SR-MA) despite their importance in the EBM process is uncommonly performed in veterinary medicine due to the absence of specific dedicated tools. The main objective of this observational study was to examine the extent and nature of SR-MA that can be available online to an equine or bovine veterinarian. Secondary objectives included: (1) to determine if A MeaSurement Tool to Assess systematic Reviews (AMSTAR) tool can be used for equine and...
Evidence-based farriery – does it exist?
Equine veterinary journal    July 11, 2018   Volume 50, Issue 5 552-553 doi: 10.1111/evj.12978
Weller R, Barstow A, Price H, Pfau T.No abstract available
A Systematic Review of the Quality of IV Fluid Therapy in Veterinary Medicine.
Frontiers in veterinary science    August 14, 2017   Volume 4 127 doi: 10.3389/fvets.2017.00127
Muir WW, Ueyama Y, Noel-Morgan J, Kilborne A, Page J.To evaluate the quality of the veterinary literature investigating IV fluid therapy in dogs, cats, horses, and cattle. Methods: Systematic review. Methods: The preferred reporting of items for systematic review and meta-analysis protocols (PRISMA-P) was employed for systematic review of all relevant IV fluid therapy manuscripts published from January 1969 through December 2016 in the Commonwealth Agricultural Bureaux International (CABI) database. Independent grading systems used to evaluate manuscripts included the updated CONsolidated Standards of Reporting Trials 2012 checklist, risk of bia...
Compounding of Veterinary Drugs for Equine Practitioners.
The Veterinary clinics of North America. Equine practice    March 23, 2017   Volume 33, Issue 1 213-225 doi: 10.1016/j.cveq.2016.12.003
Stanley SD, Moffitt K, Wiebe V.Equine practitioners should follow these recommendations when using compounded medications: (1) the decision must be veterinary driven, based on a valid veterinarian-client-patient relationship and on evidence-based medicine; (2) compliance with the Animal Medicinal Drug Use Clarification Act of 1994; and (3) use limited to (a) horses for which no other method or route of drug delivery is practical; (b) those drugs for which safety, efficacy, and stability have been demonstrated; or (c) disease conditions for which a quantifiable response to therapy or drug concentration can be monitored.
An open trial of equine-assisted therapy for children exposed to problematic parental substance use.
Health & social care in the community    February 1, 2017   Volume 25, Issue 3 1247-1256 doi: 10.1111/hsc.12427
Tsantefski M, Briggs L, Griffiths J, Tidyman A.Children exposed to problematic parental substance use (PPSU) often face a number of deleterious developmental outcomes, yet these children are less likely to become known to child protection and welfare services. Although there is a growing evidence base for equine-assisted therapy (EAT) as an effective treatment modality for atypically developing children and adolescents, scant research has explored the benefit of EAT for children exposed to PPSU. The current study is the first to explore the benefit of EAT for children exposed to PPSU in Victoria, Australia. Five 12-week EAT programmes were...
Simulating forensic casework scenarios in experimental studies: The generation of footwear marks in blood.
Forensic science international    March 18, 2016   Volume 264 34-40 doi: 10.1016/j.forsciint.2016.03.023
McElhone RL, Meakin GE, French JC, Alexander T, Morgan RM.A study was designed to investigate the effects of external variables, including blood type, flooring surface, footwear tread depth and blood dryness, on the appearance of blood-based footwear marks, with particular reference to simulating a specific casework scenario. Results showed that footwear marks left in human blood tended to be of greater quality than those in equine blood, highlighting a potential issue in applying data generated with equine blood to human bloodstains in casework. Footwear tread effects were also dependent on blood type, but the type of flooring surface did not affect...
Physiotherapy Assessment for the Equine Athlete.
The Veterinary clinics of North America. Equine practice    February 19, 2016   Volume 32, Issue 1 31-47 doi: 10.1016/j.cveq.2015.12.002
Goff L.Physiotherapy assessment of the equine athlete is carried out by qualified physiotherapists, who use a functional approach to the assessment of the horse. Observation, clinical reasoning, good palpation skills and implementation of outcome measures are skills used by these professionals in their assessment of the horse. Equine physiotherapists attempt, where possible, to use an evidence-based approach to the assessment of the equine athlete.
“Horses for Courses”: Comment on “Translating Evidence Into Healthcare Policy and Practice: Single Versus Multi-Faceted Implementation Strategies – Is There a Simple Answer to a Complex Question?”.
International journal of health policy and management    July 13, 2015   Volume 4, Issue 10 685-686 doi: 10.15171/ijhpm.2015.127
Wilkinson JE, Frost H.This commentary considers the vexed question of whether or not we should be spending time and resources on using multifaceted interventions to undertake implementation of evidence in healthcare. A review of systematic reviews has suggested that simple interventions may be just as effective as those taking a multifaceted approach. Taking cognisance of the Promoting Action on Research Implementation in Health Services (PARIHS) framework this commentary takes account of the evidence, context and facilitation factors in undertaking implementation. It concludes that a 'horses for courses' approach ...
A systematic review and meta-analysis of the efficacy of furosemide for exercise-induced pulmonary haemorrhage in Thoroughbred and Standardbred racehorses.
Equine veterinary journal    February 2, 2015   Volume 47, Issue 3 341-349 doi: 10.1111/evj.12373
Sullivan SL, Whittem T, Morley PS, Hinchcliff KW.Furosemide is the most commonly used medication for exercise-induced pulmonary haemorrhage (EIPH); however, critical evaluation of the strength of evidence for efficacy of furosemide is lacking and is warranted so that evidence-based treatment decisions can be made. Objective: To evaluate the efficacy of furosemide to reduce the severity or frequency of detection of EIPH in Thoroughbred and Standardbred racehorses. Methods: Systematic review with meta-analyses. Methods: Primary studies were identified via searches of electronic databases, relevant texts and reference lists of published article...
Equine-related treatments for mental disorders lack empirical support: a systematic review of empirical investigations.
Journal of clinical psychology    June 20, 2014   Volume 70, Issue 12 1115-1132 doi: 10.1002/jclp.22113
Anestis MD, Anestis JC, Zawilinski LL, Hopkins TA, Lilienfeld SO.Equine-related treatments (ERT) for mental disorders are becoming increasingly popular for a variety of diagnoses; however, they have been subjected only to limited systematic investigation. Objective: To examine the quality of and results from peer-reviewed research on ERT for mental disorders and related outcomes. Methods: Peer-reviewed studies (k = 14) examining treatments for mental disorders or closely related outcomes were identified from databases and article reference sections. Results: All studies were compromised by a substantial number of threats to validity, calling into question t...
Systematic evaluation of evidence on veterinary viscoelastic testing part 1: System comparability.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    January 14, 2014   Volume 24, Issue 1 23-29 doi: 10.1111/vec.12143
McMichael M, Goggs R, Smith S, Wagg C, Warman S, Wiinberg B.To systematically examine the evidence on system comparability between the thromboelastography and the rotational thromboelastometry viscoelastic point-of-care instruments and to identify knowledge gaps. Methods: Standardized, systematic evaluation of the literature, categorization of relevant articles according to level of evidence and quality, and development of consensus on conclusions for application of the concepts to clinical practice. Methods: Academic and referral veterinary medical centers. Results: Medline via PubMed, CAB abstracts, and Google Scholar were searched. A total of 8 rele...
Elasticity and breaking strength of synthetic suture materials incubated in various equine physiological and pathological solutions.
Equine veterinary journal    November 20, 2013   Volume 46, Issue 4 494-498 doi: 10.1111/evj.12181
Kearney CM, Buckley CT, Jenner F, Moissonnier P, Brama PA.Selection of suture material in equine surgery is often based on costs or subjective factors, such as the surgeon's personal experience, rather than objective facts. The amount of objective data available on durability of suture materials with regard to specific equine physiological conditions is limited. Objective: To evaluate the effect of various equine physiological and pathological fluids on the rate of degradation of a number of commonly used suture materials. Methods: In vitro material testing. Methods: Suture materials were exposed in vitro to physiological fluid, followed by biomechan...
Oral examination and charting: setting the basis for evidence-based medicine in the oral examination of equids.
The Veterinary clinics of North America. Equine practice    June 27, 2013   Volume 29, Issue 2 325-vi doi: 10.1016/j.cveq.2013.04.008
Menzies R.The oral examination is performed in equids to assess and monitor oral health status, provide diagnoses, and determine efficacy of treatments. While there is currently insufficient scientific material of adequate quality to enable evidence-based medicine in equine dentistry, this by no means negates the clinician's responsibility to provide oral health care in a scientific and ethical manner. To do so requires that the clinician be knowledgable and skilled in dentistry and general medicine, that each case upholds the principles of scientific method, and that data is gathered and appraised in a...
Eating disorders and equine therapy: a nurse’s perspective on connecting through the recovery process.
Journal of psychosocial nursing and mental health services    June 21, 2013   Volume 51, Issue 9 24-31 doi: 10.3928/02793695-20130612-01
Dezutti JE.Patients with eating disorders may have the most complex interdisciplinary treatment plans of any mental illness. Nurses need innovative evidence-based treatment interventions to assist their patients with eating disorders on their road to recovery. Although much has been written about equine-assisted psychotherapy (EAP) and equine-facilitated psychotherapy, the literature has not described a detailed session that can help nurses understand how this experiential treatment works and the impact it can have on the patient. A review of the literature on eating disorders and on the use of equine th...