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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Helminthic transmission and isolation of Ehrlichia risticii, the causative agent of Potomac horse fever, by using trematode stages from freshwater stream snails.
Journal of clinical microbiology    March 4, 2000   Volume 38, Issue 3 1293-1297 doi: 10.1128/JCM.38.3.1293-1297.2000
Pusterla N, Madigan JE, Chae JS, DeRock E, Johnson E, Pusterla JB.We report successful helminthic transmission of Ehrlichia risticii, the causative agent of Potomac horse fever, using trematode stages collected from Juga yrekaensis snails. The ehrlichial agent was isolated from the blood of experimentally infected horses by culture in murine monocytic cells and identified as E. risticii ultrastructurally and by characterization of three different genes.
Safety of omeprazole paste in foals and mature horses.
Equine veterinary journal. Supplement    March 4, 2000   Issue 29 63-66 doi: 10.1111/j.2042-3306.1999.tb05172.x
Plue RE, Wall HG, Daurio C, Attebery DK, Cox JL, Wallace DH.Omeprazole has been shown to promote healing of spontaneously occurring gastric ulcers in horses when administered for 28 days at a dose of 4 mg/kg bwt/day and to prevent recurrence of ulcers in almost all horses when treatment is continued at a dose of at least 2 mg/kg bwt/day. The purpose of the 3 studies reported here was to 1) evaluate the evolution of potential effects of omeprazole paste (GastroGard), at a dose of 20 mg/kg bwt/day (5x the recommended dose) for 91 days in mature Thoroughbred horses; 2) evaluate the safety in young horses of omeprazole paste when dosed at 4 mg/kg bwt/day (...
Pathophysiology of peptic disorders in foals and horses: a review.
Equine veterinary journal. Supplement    March 4, 2000   Issue 29 14-18 doi: 10.1111/j.2042-3306.1999.tb05162.x
Murray MJ.No abstract available
Use of 99mTc-mercaptoacetyltriglycine to evaluate renal function in horses. Woods PR, Drost WT, Clarke CR, Rodebush CJ.Ten healthy horses were injected intravenously with 99mTc-MAG3 and the disappearance of radioactivity from the blood was measured. The total body clearance (Cl(B)) and elimination half-life (t1/2(beta)) were 7.9 +/- 1.5 ml/kg/minute and 32.8 +/- 4.1 minutes, respectively. The disappearance of 99mTc-MAG3 from the blood of 2 horses with compromised renal function was also measured. The data suggest that 99mTc-MAG3 is a useful and clinically applicable radiopharmaceutical for measurement of effective renal blood flow in the horse.
Measurements of hindlimb blood flow recorded using Doppler ultrasound during administration of vasoactive agents in halothane-anesthetized horses. Raisis AL, Young LE, Meire HB, Taylor PM, Blissitt KJ, Marlin D, Lekeux P.The purpose of the study was to determine the ability of Doppler ultrasound to detect changes in femoral blood flow during pharmacologic manipulation of arterial blood pressure. Doppler ultrasonography was performed in the femoral vessels of six halothane-anesthetized horses before and during administration of phenylephrine HCI and sodium nitroprusside. The time-averaged mean velocity and volumetric flow were calculated. The contour of the velocity waveform was assessed, and the early diastolic deceleration slope (EDDS) and pulsatility index (PI) were calculated. Administration of phenylephrin...
Radiographic diagnosis: thoracic spinal fracture resulting in kyphosis in a horse. Kothstein T, Rashmir-Raven AM, Thomas MW, Brashier MK.No abstract available
Staining abnormalities of dermal collagen in eosinophil- or neutrophil-rich inflammatory dermatoses of horses and cats as demonstrated with Masson’s trichrome stain.
Veterinary dermatology    March 1, 2000   Volume 11, Issue 1 43-48 doi: 10.1046/j.1365-3164.2000.00172.x
Fernandez CJ, Scott DW, Erb HN.A retrospective study was performed on skin biopsy specimens from horses and cats having eosinophilic granulomas with 'collagen degeneration', eosinophilic skin diseases without 'collagen degeneration' and pyogranulomas without 'collagen degeneration'. Neither the appearance of collagen fibres nor the dominant polymorphonuclear cells, as seen in H & E-stained sections, were predictive of Masson's trichrome findings. Hence, a Masson's trichrome staining abnormality of collagen fibres was no more likely to be present in lesions with 'collagen degeneration' than in those lesions without 'coll...
The genetic structure of Spanish Celtic horse breeds inferred from microsatellite data.
Animal genetics    February 26, 2000   Volume 31, Issue 1 39-48 doi: 10.1046/j.1365-2052.2000.00591.x
Cañon J, Checa ML, Carleos C, Vega-Pla JL, Vallejo M, Dunner S.Partition of the genetic variability, genetic structure and relationships among seven Spanish Celtic horse breeds were studied using PCR amplification of 13 microsatellites on 481 random individuals. In addition, 60 thoroughbred horses were included. The average observed heterozygosity and the mean number of alleles were higher for the Atlantic horse breeds than for the Balearic Islands breeds. Only eight percentage of the total genetic variability could be attributed to differences among breeds (mean FST approximately 0.08; P < 0.01). Atlantic breeds clearly form a separate cluster from th...
Improvement of western blot test specificity for detecting equine serum antibodies to Sarcocystis neurona. Rossano MG, Mansfield LS, Kaneene JB, Murphy AJ, Brown CM, Schott HC, Fox JC.Equine protozoal myeloencephalitis (EPM) is a neurological disease of horses and ponies caused by the apicomplexan protozoan parasite Sarcocystis neurona. The purposes of this study were to develop the most stringent criteria possible for a positive test result, to estimate the sensitivity and specificity of the EPM Western blot antibody test, and to assess the ability of bovine antibodies to Sarcocystis cruzi to act as a blocking agent to minimize false-positive results in the western blot test for S. neurona. Sarcocystis neurona merozoites harvested from equine dermal cell culture were heat ...
Immune cell populations in the equine corpus luteum throughout the oestrous cycle and early pregnancy: an immunohistochemical and flow cytometric study.
Journal of reproduction and fertility    February 26, 2000   Volume 117, Issue 2 281-290 doi: 10.1530/jrf.0.1170281
Lawler DF, Hopkins J, Watson ED.Recent evidence indicates that the cells of the immune system and their large network of secretory products, or cytokines, play an active role in the ovary throughout the oestrous cycle. In the present study, immune cell populations (T and B lymphocytes, macrophages, granulocytes and eosinophils) and expression of major histocompatibility complex (MHC) class II were investigated in corpora lutea from mares in early (days 2-4), mid- (days 7-10) and late (days 12-14) dioestrus, the post-luteolytic phase (days 16-17) and early pregnancy. The number of T lymphocytes within the corpus luteum increa...
Ten equine microsatellite loci: TKY25, TKY26, TKY27, TKY28, TKY29, TKY267, TKY268, TKY269, TKY270 and TKY271.
Animal genetics    February 26, 2000   Volume 31, Issue 1 68-69 doi: 10.1111/j.1365-2052.2000.579-1.x
Kakoi H, Tozaki T, Hirota K, Mashima S, Kurosawa M, Miura N.No abstract available
Characterization of ten equine dinucleotide microsatellite loci: NVHEQ21, NVHEQ54, NVHEQ67, NVHEQ70, NVHEQ75, NVHEQ77, NVHEQ79, NVHEQ81, NVHEQ82 and NVHEQ83.
Animal genetics    February 26, 2000   Volume 31, Issue 1 78-79 doi: 10.1111/j.1365-2052.2000.579-13.x
Bjørnstad G, Midthjell L, Røed KH.No abstract available
Procedurally similar competitive immunoassay systems for the serodiagnosis of Babesia equi, Babesia caballi, Trypanosoma equiperdum, and Burkholderia mallei infection in horses. Katz J, Dewald R, Nicholson J.Procedurally similar competitive enzyme-linked immunoassay (cELISA) methods were developed for the serodiagnosis of Babesia equi and Babesia caballi (piroplasmosis), Trypanosoma equiperdum (dourine), and Burkholderia mallei (glanders) infections in horses. Apparent test specificities for the B. equi, B. caballi, T. equiperdum, and B. mallei cELISAs were 99.2%, 99.5%, 98.9%, and 98.9%, respectively. Concordances and kappa values between the complement fixation (CF) and the cELISA procedures for the serodiagnosis of B. equi, B. caballi, T. equiperdum, and B. mallei infections in experimentally e...
Isolation of Jamestown Canyon virus (California virus group) from vesicular lesions of a horse. Sahu SP, Landgraf J, Wineland N, Pedersen D, Alstad D, Gustafson G.No abstract available
Intrapelvic hemangiosarcoma in a horse. Kiupel M, Frank N, Stevenson GW, Siems J, Snyder PW.No abstract available
A pedigree-based study of mitochondrial D-loop DNA sequence variation among Arabian horses.
Animal genetics    February 26, 2000   Volume 31, Issue 1 1-7 doi: 10.1046/j.1365-2052.2000.00558.x
Bowling AT, Del Valle A, Bowling M.Through DNA sequence comparisons of a mitochondrial D-loop hypervariable region, we investigated matrilineal diversity for Arabian horses in the United States. Sixty-two horses were tested. From published pedigrees they traced in the maternal line to 34 mares acquired primarily in the mid to late 19th century from nomadic Bedouin tribes. Compared with the reference sequence (GenBank X79547), these samples showed 27 haplotypes with altogether 31 base substitution sites within 397 bp of sequence. Based on examination of pedigrees from a random sampling of 200 horses in current studbooks of the A...
Correlation of two nonradioactive immunoassays to a radioimmunoassay technique for thyroxine measurement in equine serum. Solter PF, Farner S.The purpose of this study was to compare 2 different nonradioactive assay methods with a conventional radioimmunoassay (RIA) measuring the concentration of serum thyroxine (T4) in horses. Serum was obtained from 85 adult standardbred horses. The T4 concentration of each sample was analyzed by RIA, chemiluminescent enzyme immunoassay (CEI), and homogeneous enzyme immunoassay (HEI). The correlation between the HEI method and RIA method was significantly greater (r = 0.89) than the correlation between the CEI and the reference method (r = 0.53). In addition, the precision of the HEI method was si...
Descriptive epidemiologic study of disease associated with influenza virus infections during three epidemics in horses.
Journal of the American Veterinary Medical Association    February 25, 2000   Volume 216, Issue 4 535-544 doi: 10.2460/javma.2000.216.535
Morley PS, Townsend HG, Bogdan JR, Haines DM.To describe 3 epidemics of respiratory tract disease caused by influenza virus infections in a large population of horses. Methods: Cross-sectional and prospective longitudinal observational studies. Methods: All horses stabled at a Thoroughbred racetrack. Methods: During a 3-year period, descriptive information was collected as horses arrived at the racetrack and throughout race meetings. Routine observations and physical examinations were used to classify horses' disease status. Cause of epidemics was established by use of serologic testing and identification of influenza virus in nasal secr...
Risk factors for disease associated with influenza virus infections during three epidemics in horses.
Journal of the American Veterinary Medical Association    February 25, 2000   Volume 216, Issue 4 545-550 doi: 10.2460/javma.2000.216.545
Morley PS, Townsend HG, Bogdan JR, Haines DM.To identify risk factors associated with respiratory tract disease in horses during 3 epidemics caused by influenza virus infections. Methods: Cross-sectional and prospective longitudinal observational studies. Methods: 1,163 horses stabled at a Thoroughbred racetrack. Methods: Investigations were conducted during a 3-year period. An epidemic of respiratory tract disease caused by influenza virus infections was identified in each year. Routine observations and physical examinations were used to classify horses' disease status. Data were analyzed to identify factors associated with development ...
Treatment advances reported at equine meeting.
Journal of the American Veterinary Medical Association    February 25, 2000   Volume 216, Issue 4 468-469 
Korioth TI.No abstract available
Squamous cell carcinoma of the urethral process in a horse with hemospermia and self-mutilation behavior.
Journal of the American Veterinary Medical Association    February 25, 2000   Volume 216, Issue 4 551-518 doi: 10.2460/javma.2000.216.551
Bedford SJ, McDonnell SM, Tulleners E, King D, Habecker P.A 14-year-old Arabian stallion was examined because of acute hemospermia. The stallion was used in an artificial breeding program and had a 6-year history of low-grade hemospermia and a 4-year history of self-mutilation behavior. During previous examinations, minor irritation of the urethral process was identified as the source of the bleeding. Physical examination revealed a mucosal ulceration in the distal portion of the urethra. Histologic examination of a biopsy specimen from this area revealed low-grade squamous cell carcinoma. The urethral process was excised, and the hemospermia resolve...
Causes of poor performance of horses during training, racing, or showing: 348 cases (1992-1996).
Journal of the American Veterinary Medical Association    February 25, 2000   Volume 216, Issue 4 554-558 doi: 10.2460/javma.2000.216.554
Martin BB, Reef VB, Parente EJ, Sage AD.To determine results for horses undergoing a high-speed treadmill examination, including videoendoscopy of the pharynx and larynx before and during exercise, echocardiography before and after exercise, and electrocardiography before, during, and after exercise, because of poor performance. Methods: Retrospective study. Methods: 348 horses. Results: A definitive diagnosis was obtained for 256 (73.5%) horses. One hundred forty-eight horses had dynamic obstruction of the airway during exercise, 33 had clinically important cardiac arrhythmias alone, 22 had a combination of dynamic airway obstructi...
Cutaneous phycomycosis in two horses.
Australian veterinary journal    February 24, 2000   Volume 77, Issue 12 780-783 doi: 10.1111/j.1751-0813.1999.tb12942.x
Dowling BA, Dart AJ, Kessell AE, Pascoe RR, Hodgson DR.No abstract available
Postoperative performance of racing horses with tearing of the medial palmar intercarpal ligament.
Australian veterinary journal    February 24, 2000   Volume 77, Issue 11 713-717 doi: 10.1111/j.1751-0813.1999.tb12905.x
Whitton RC, Kannegieter NJ, Rose RJ.To examine the relationship between medial palmar intercarpal ligament (MPICL) tearing and postoperative performance in racing horses. Methods: The postoperative performance of 42 horses in which the midcarpal joint was examined arthroscopically was followed prospectively. Intra-articular variables examined were the severity of MPICL tearing, subchondral bone damage and articular cartilage damage. Using a scoring system based on the class of race and the position in the race, a mean score was calculated for up to five races before and after surgery. The preoperative score was subtracted from t...
Cutaneous phycomycosis in two horses.
Australian veterinary journal    February 24, 2000   Volume 77, Issue 12 780-783 doi: 10.1111/j.1751-0813.1999.tb12942.x
Dowling BA, Dart AJ, Kessell AE, Pascoe RR, Hodgson DR.No abstract available
Kinematics and ground reaction forces in horses with superficial digital flexor tendinitis.
American journal of veterinary research    February 24, 2000   Volume 61, Issue 2 191-196 doi: 10.2460/ajvr.2000.61.191
Clayton HM, Schamhardt HC, Willemen MA, Lanovaz JL, Colborne GR.To measure and correlate kinematic and ground reaction force (GRF) data in horses with superficial digital flexor tendinitis. Methods: 6 sound horses. Methods: Horses were evaluated before (sound evaluation) and after (lame evaluation) induction of superficial digital flexor tendinitis in 1 forelimb (randomized) by injection of collagenase. As each horse trotted, kinematic data were collected by use of an optoelectronic system, and GRF data were measured by use of a force plate. Three-dimensional kinematic and GRF data were projected onto a 2-dimensional sagittal plane. Results: Lame limbs had...
Comparison of sensitivity of sodium currents to tetrodotoxin in equine muscle specimens with that in murine and human muscle specimens.
American journal of veterinary research    February 24, 2000   Volume 61, Issue 2 133-138 doi: 10.2460/ajvr.2000.61.133
Beech J, Fletcher JE, Erwin K, Lindborg SR.To determine sensitivity of equine skeletal muscle to tetrodotoxin and compare that with sensitivity of murine and human skeletal muscles. Methods: Semimembranosus, vastus lateralis, triceps brachii, and masseter muscle specimens from 22 euthanatized horses, vastus lateralis muscle biopsy specimens from 25 clinically normal humans, and diaphragmatic muscle specimens from 6 mice. Methods: Electrically elicited twitch responses were measured in muscle specimens incubated in medium alone and with tetrodotoxin (100 nM, 400 nM, 1.6 microM for equine specimens and 100 nM, 200 nM, 400 nM, 800 nM, 1.6...
Correlation of clinical score, intrapleural pressure, cytologic findings of bronchoalveolar fluid, and histopathologic lesions of pulmonary tissue in horses with summer pasture-associated obstructive pulmonary disease.
American journal of veterinary research    February 24, 2000   Volume 61, Issue 2 167-173 doi: 10.2460/ajvr.2000.61.167
Costa LR, Seahorn TL, Moore RM, Taylor HW, Gaunt SD, Beadle RE.To correlate clinical score, intrapleural pressure, cytologic findings of bronchoalveolar lavage fluid (BALF), and histologic lesions of pulmonary tissue in horses affected with summer pasture-associated obstructive pulmonary disease (SPAOPD). Methods: 8 adult horses affected with SPAOPD and 6 adult horses without evidence of respiratory tract disease. Methods: Clinical score, change in intrapleural pressure (deltaPpl) during tidal breathing, results of cytologic examination and bacteriologic culture of BALF, and results of histologic examination of pulmonary parenchyma were evaluated. Results...
Ulceration and stricture of the right dorsal colon after phenylbutazone administration in four horses.
Australian veterinary journal    February 24, 2000   Volume 77, Issue 12 785-788 doi: 10.1111/j.1751-0813.1999.tb12945.x
Hough ME, Steel CM, Bolton JR, Yovich JV.Four cases of ulceration and stricture of the right dorsal colon were encountered. Ulceration of the right dorsal colon is generally associated with nonsteroidal anti-inflammatory drug (NSAID) toxicosis but there are few reports of stricture following ulceration. All four horses had recent phenylbutazone use: three had been given doses well in excess of the recommended dose and in one the dose was marginally above those recommended but was combined with administration of other NSAIDs. All four horses presented with intermittent low-grade colic, weight loss and ventral oedema. Diarrhoea was als...
Doppler ultrasonographic features of thoracic limb arteries in clinically normal horses.
American journal of veterinary research    February 24, 2000   Volume 61, Issue 2 183-190 doi: 10.2460/ajvr.2000.61.183
Cochard T, Toal RL, Saxton AM.To determine blood flow velocities and indices from spectral waveforms obtained by use of Doppler ultrasonography of thoracic limb arteries of horses and to assess interobserver and patient variability associated with the technique. Methods: 9 clinically normal adult horses. Methods: Left thoracic limb arteries of 8 nonsedated horses were examined at 5 sites by use of pulsed-wave Doppler ultrasonography to determine a range of values for peak systolic, end diastolic, and mean velocities and resistive and pulsatility indices. Interobserver and patient variabilities were determined by 2 operator...