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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Hyperkalaemic periodic paralysis in horses: a review.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 362-367 doi: 10.1111/j.2042-3306.1999.tb03834.x
Meyer TS, Fedde MR, Cox JH, Erickson HH.No abstract available
Cell proliferation patterns in the equine endometrium throughout the non-pregnant reproductive cycle.
Journal of reproduction and fertility    October 3, 1999   Volume 116, Issue 1 167-175 doi: 10.1530/jrf.0.1160167
Gerstenberg C, Allen WR, Stewart F.Immunohistochemical detection of the proliferation marker Ki-67 antigen was used to monitor mitotic activity in the endometrium of mares. The monoclonal antibody MIB1 was validated for use on equine tissues by demonstrating its reaction with activated peripheral blood lymphocytes, and endometrial biopsies were recovered from 26 non-pregnant mares at selected stages during the reproductive cycle. The proportion of positively stained nuclei was counted in five random areas on each histological section to determine the percentage and type of proliferating cells. Multiplication rates in the types ...
Tachypnoea associated with a diaphragmatic tear in a horse.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 443-445 doi: 10.1111/j.2042-3306.1999.tb03846.x
Goehring LS, Goodrich LR, Murray MJ.No abstract available
Equine dental disease part 1: a long-term study of 400 cases: disorders of incisor, canine and first premolar teeth.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 369-377 doi: 10.1111/j.2042-3306.1999.tb03835.x
Dixon PM, Tremaine WH, Pickles K, Kuhns L, Hawe C, McCann J, McGorum B, Railton DI, Brammer S.A review of 400 horses referred because of dental disorders showed 44 cases to suffer from primary disorders of their incisors and 11 from canine or 1st premolar teeth disorders. The remaining 345 horses suffered from primary disorders of the cheek teeth. Disorders of incisors included traumatic damage to teeth and their supporting bones, retained deciduous, displaced and supernumerary incisors; brachygnathia and abnormalities of wear, with most of the latter disorders being secondary to primary disorders of the cheek teeth Only 3 cases of apical infection of incisors were recognised. Most cas...
[Cowpox viruses in Germany: an analysis of 5 cases in 1998].
Berliner und Munchener tierarztliche Wochenschrift    October 3, 1999   Volume 112, Issue 9 334-338 
Pfeffer M, Burck G, Meyer H.Five case reports on cowpox virus infections in cats, humans, and for the first time in a horse are presented. It becomes obvious that in most cases the diagnosis cowpox is suspected rather late, although fast and reliable diagnostic tools such as pathohistological examination and polymerase chain reaction are available. The threat of a zoonotic transmission mainly through cats is gaining importance. Although wild rodents have been claimed to be the reservoir and source for cowpox viruses in cats, very little is known about the epidemiology of cowpox virus. Based on the different genome organi...
Determination of equid herpesvirus 1-specific, CD8+, cytotoxic T lymphocyte precursor frequencies in ponies.
Veterinary immunology and immunopathology    October 3, 1999   Volume 70, Issue 1-2 43-54 doi: 10.1016/s0165-2427(99)00037-9
O'Neill T, Kydd JH, Allen GP, Wattrang E, Mumford JA, Hannant D.The frequency of antigen-specific, genetically restricted cytotoxic T lymphocyte precursors (CTLp) was measured in peripheral blood mononuclear cells (PBMC) of ponies before and after infection with equid herpesvirus 1 (EHV1). Split-well limiting dilution analysis (LDA) was developed to measure CTLp frequency using EHV1-infected 51Cr-labelled lymphoblasts as targets. Extensive characterisation showed that recombinant human interleukin-2, autologous antigen presenting cells and equine serum containing virus neutralising antibody were necessary for maturation of CTLp into effector CTL in vitro. ...
Radiological measurements from the feet of normal horses with relevance to laminitis.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 427-432 doi: 10.1111/j.2042-3306.1999.tb03844.x
Cripps PJ, Eustace RA.Lateromedial radiographic projections were made from the feet of 25 normal horses and 3 angles and 3 distances were measured. From these, normal ranges of calculated variables were obtained. The width and length of each foot and the height of the horse at the withers was also measured. In view of its possible importance in clinical laminitis, particular attention was paid to 'founder' distance (D). This is the vertical distance between the proximal limit of the dorsal hoof wall and the proximal limit of the extensor process of the distal phalanx. There were significant differences between bree...
Myeloblastic leukaemia in a Morgan horse mare.
Equine veterinary journal    October 3, 1999   Volume 31, Issue 5 446-448 doi: 10.1111/j.2042-3306.1999.tb03847.x
Clark P, Cornelisse CJ, Schott HC, Swenson CL, Bell TG.No abstract available
Government reviews animal welfare during transport.
The Veterinary record    September 30, 1999   Volume 145, Issue 9 238 
No abstract available
Evaluation of antibody parameters as potential correlates of protection or enhancement by experimental vaccines to equine infectious anemia virus.
Virology    September 30, 1999   Volume 262, Issue 2 416-430 doi: 10.1006/viro.1999.9939
Hammond SA, Raabe ML, Issel CJ, Montelaro RC.We previously demonstrated in trials of a variety of experimental vaccines to equine infectious anemia virus (EIAV) a remarkable spectrum of efficacy ranging from sterilizing protection to severe enhancement of virus replication and disease, depending on the immunization strategy used. This range of vaccine efficacy observed in vivo offers a unique opportunity for evaluating potential in vitro immune correlates of protection and enhancement. We describe here a comprehensive analysis and comparison of EIAV envelope-specific antibody responses elicited by attenuated, inactivated whole virus and ...
Bioavailability of racemic ketoprofen in healthy horses following rectal administration.
Research in veterinary science    September 30, 1999   Volume 67, Issue 2 203-204 doi: 10.1053/rvsc.1999.0303
Corveleyn S, Henrist D, Remon JP, Van Der Weken G, Baeyens W, Haustraete J, Aboul-Enein HY, Sustronck B, Deprez P.Ketoprofen (KTP) is a chiral non-steroidal anti-inflammatory drug (NSAID) of the propionic acid class, approved by the FDA for the allevation of pain associated with musculoskeletal disorders in horses. The present study was designed to examine the bioavailability of ketoprofen enantiomers after rectal administration of the racemate to healthy horses. One gram of racemic ketoprofen was injected intravenously and administered rectally as a fat based suppository in a cross-over design study (n = 4). Blood samples were analysed for KTP enantiomers using HPLC. After IV administration, the S(+) ena...
Lameness associated with the bicipital bursa in an Arab stallion.
The Veterinary record    September 29, 1999   Volume 145, Issue 7 194-198 doi: 10.1136/vr.145.7.194
Booth TM.Severe, chronic lameness in the left forelimb of a five-year-old Arab stallion was localised to the bicipital bursa by local anaesthesia and gamma scintigraphy. Radiographic and ultrasonographic examinations of the proximal humeral tubercles and bicipital bursa revealed new bone production in the region of the intertubercular grooves and irregularities in the density of the soft tissues of the bicipital tendon and bursa. An endoscopic examination of the bicipital bursa with a standard arthroscope under general anaesthesia was a useful diagnostic procedure. The stallion was euthanased, and mark...
Nematode control in eventer horses.
The Veterinary record    September 29, 1999   Volume 145, Issue 7 200-201 doi: 10.1136/vr.145.7.200
Pascoe RJ, Wilson TJ, Coles GC.No abstract available
Endothelial cell infection in vivo by equine infectious anaemia virus.
The Journal of general virology    September 29, 1999   Volume 80 ( Pt 9) 2393-2397 doi: 10.1099/0022-1317-80-9-2393
Oaks JL, Ulibarri C, Crawford TB.Equine infectious anaemia virus (EIAV) infection of horses is characterized clinically by recurrent episodes of fever, thrombocytopenia and anaemia. In vivo, the only site of virus replication that has been previously demonstrated for EIAV is the tissue macrophage. In this study, in situ hybridization for EIAV was combined with immunohistochemistry for cell-type-specific markers to identify infected endothelial cells. EIAV-infected endothelial cells and macrophages were detected in horses infected with either virulent wild-type or with weakly virulent tissue culture-adapted strains of EIAV. Th...
Epidemiological studies of equine herpesvirus 1 (EHV-1) in Thoroughbred foals: a review of studies conducted in the Hunter Valley of New South Wales between 1995 and 1997.
Veterinary microbiology    September 29, 1999   Volume 68, Issue 1-2 15-25 doi: 10.1016/s0378-1135(99)00057-7
Gilkerson JR, Whalley JM, Drummer HE, Studdert MJ, Love DN.Sero-epidemiological studies conducted between 1995 and 1997 on two large Thoroughbred stud farms in the Hunter Valley of NSW showed clear evidence of EHV-1 infection in foals as young as 30 days of age. Similarly, serological evidence suggested that these foals were infected with EHV-1 from their dams or from other lactating mares in the group, with subsequent foal to foal spread of infection prior to weaning. These studies also provided evidence of EHV-1 infection of foals at and subsequent to weaning, with foal to foal spread of EHV-1 amongst the weanlings. These data indicated that the mar...
Comparison of the pathogenesis of acute equine herpesvirus 1 (EHV-1) infection in the horse and the mouse model: a review.
Veterinary microbiology    September 29, 1999   Volume 68, Issue 1-2 3-13 doi: 10.1016/s0378-1135(99)00056-5
Walker C, Love DN, Whalley JM.The mouse models of the respiratory and abortion forms of equine herpesvirus 1 (EHV-1) infection have been used to investigate the vaccine potential of various EHV-1 immunogens, the effect of antiviral agents on EHV-1 infection and the pathogenicity of EHV-1 strain variants and deletion or insertional mutants. This review examines the similarities and differences in the pathogenesis of primary EHV-1 infection in the natural host, the horse, and in the mouse by comparing tissue tropism, clinical signs of infection, the effects of EHV-1 on pregnancy, haematological changes following infection, v...
Epidemiology of EHV-1 and EHV-4 in the mare and foal populations on a Hunter Valley stud farm: are mares the source of EHV-1 for unweaned foals.
Veterinary microbiology    September 29, 1999   Volume 68, Issue 1-2 27-34 doi: 10.1016/s0378-1135(99)00058-9
Gilkerson JR, Whalley JM, Drummer HE, Studdert MJ, Love DN.The prevalence of EHV-1 and EHV-4 antibody-positive horses was determined using a type specific ELISA on serum samples collected from 229 mares and their foals resident on a large Thoroughbred stud farm in the Hunter Valley of New South Wales in February 1995. More than 99% of all mares and foals tested were EHV-4 antibody positive, while the prevalence of EHV-1 antibody positive mares and foals were 26.2 and 11.4%, respectively. Examination of the ELISA absorbance data for the individual mares and foals suggested that the EHV-1 antibody positive foals had been infected recently with EHV-1 and...
Ragwort poisoning.
The Veterinary record    September 28, 1999   Volume 145, Issue 8 236 
Cook RR.No abstract available
Pharmacokinetics and bioequivalence of two suxibuzone oral dosage forms in horses.
Journal of veterinary pharmacology and therapeutics    September 28, 1999   Volume 22, Issue 4 247-254 doi: 10.1046/j.1365-2885.1999.00219.x
Jaraiz V, Rodriguez C, San Andres MD, Gonzalez F, San Andres MI.A disposition and bioequivalence study with a suxibuzone granulated and a suxibuzone paste oral formulation was performed in horses. Suxibuzone (SBZ) is a nonsteroidal anti-inflammatory drug, which was administered to horses (n = 6) at a dosage of 19 mg/kg bwt by the oral route (p.o.) in a two period cross-over design. Suxibuzone is very rapidly transformed into its main active metabolites, phenylbutazone (PBZ) and oxyphenbutazone (OPBZ). Therefore plasma and synovial fluid concentrations of SBZ, PBZ and OPBZ were simultaneously measured by a sensitive and specific high-performance liquid chro...
Tumor necrosis factor and interleukin-6 activity and endotoxin concentration in peritoneal fluid and blood of horses with acute abdominal disease.
Journal of veterinary internal medicine    September 28, 1999   Volume 13, Issue 5 457-464 doi: 10.1892/0891-6640(1999)013<0457:tnfaia>2.3.co;2
Barton MH, Collatos C.The purpose of this study was to evaluate the diagnostic and prognostic significance of tumor necrosis factor-alpha (TNF) and interleukin-6 (IL-6) activities and endotoxin concentration in blood and peritoneal fluid of 155 adult horses with acute abdominal disease (colic). Samples also were obtained from 20 healthy adult horses. Blood and peritoneal fluid supernatant TNF and IL-6 activities and endotoxin concentration were significantly greater in horses with colic, compared with healthy horses. In horses with colic, the peritoneal fluid endotoxin concentration and TNF and IL-6 activities were...
Theriogenology question of the month. Septic orchitis-periorchitis and epididymitis.
Journal of the American Veterinary Medical Association    September 25, 1999   Volume 215, Issue 6 787-789 
Kasaback CM, Rashmir-Raven AM, Black SS.No abstract available
Jejunoileal incarceration and strangulation through a splenic defect in a mare.
The Canadian veterinary journal = La revue veterinaire canadienne    September 25, 1999   Volume 40, Issue 9 657-658 
Hélie P, Ammann VJ, Kervern I.A 6-year-old, standardbred mare was presented for colic of 12 h duration. Transrectal palpation revealed intestinal distension of unknown cause. The mare was euthanized. At necropsy, segmental jejunoileal incarceration and strangulation through an opening in the spleen was observed. This opening was considered to be a congenital defect.
Inter-relationship between Gasterophilus larvae and the horse’s gastric and duodenal wall with special reference to penetration.
Veterinary parasitology    September 25, 1999   Volume 86, Issue 2 127-142 doi: 10.1016/s0304-4017(99)00119-3
Cogley TP, Cogley MC.The degree of penetration into the stomach and duodenum of the horse by bot fly larvae, Gasterophilus intestinalis (De Geer) and G. nasalis (Linnaeus) (Diptera : Gasterophilidae) was evaluated. Evidence of larval perforation of the stomach or duodenum was not found on gross inspection. Palpation of the intact stomach and duodenum was not effective in establishing the existence of Gasterophilus larvae within the organs. Findings suggest that larvae of both species produce an ulcer of similar depth within the gastrointestinal wall. The ulcer depth produced by larvae did not correlate with the no...
Actinobacillus lignieresii infection in two horses.
Journal of the American Veterinary Medical Association    September 25, 1999   Volume 215, Issue 6 826-796 
Carmalt JL, Baptiste KE, Chirino-Trejo JM.A 10-year-old pregnant Norwegian Fjord horse was examined for gross swelling of the muzzle of 2 years' duration. Examination of biopsy specimens revealed diffuse dermal fibrosis, micropustule formation, and vascular thrombosis; large numbers of Actinobacillus lignieresii were isolated in pure culture. Prolonged treatment with i.v. administration of sodium iodide and oral administration of trimethoprim-sulfamethoxazole caused regression of the swelling and did not induce abortion. A 5-month-old American Paint filly was examined for swelling in the udder region. Bacteriologic culture of purulent...
Diagnosis and surgical treatment of periapical infection of the third mandibular molar in five horses.
Journal of the American Veterinary Medical Association    September 25, 1999   Volume 215, Issue 6 829-796 
Gayle JM, Redding WR, Vacek JR, Bowman KF.Diagnosis and treatment of periapical infection of the third mandibular molar in 5 horses was assessed. In 4 of 5 horses, there was a recent history of dental work performed. Diagnosis required multiple imaging techniques. Radiography revealed evidence of periapical bone lysis or tooth root lysis of the third mandibular molar in 3 of 5 horses. Sonographic examination was effective in identifying abscesses within the masseter muscle and defects of the lateral cortex of the mandible in 4 of 5 horses. Nuclear scintigraphy was diagnostic in 1 of 2 horses examined. All horses were treated by repuls...
Three-dimensional ultrastructure of synoviocytes in the horse joint as revealed by the scanning electron microscope.
Archives of histology and cytology    September 25, 1999   Volume 62, Issue 3 219-229 doi: 10.1679/aohc.62.219
Shikichi M, Kitamura HP, Yanase H, Konno A, Takahashi-Iwanaga H, Iwanaga T.The synovial membrane displays a superficial cellular lining composed of two types of synoviocytes: "absorptive" macrophages (type A cells) and "secretory" fibroblast-like cells (type B cells). The types are intermingled and extend a variety of processes, rendering the cellular architecture of the synovial membrane difficult to visualize. Previous electron microscopic and histochemical studies failed to demonstrate the entire shape of synoviocytes, except our immunohistochemical study for protein gene product 9.5 in the horse joint. The present SEM study is the first to demonstrate the three-d...
Small intestine strangulation by components of the spermatic cord in two geldings.
Journal of the American Veterinary Medical Association    September 25, 1999   Volume 215, Issue 6 824-796 
Moll HD, Howard RD, May KA, Cheramie HS.Two adult Quarter Horse geldings were evaluated for signs of abdominal pain. Both horses had signs of depression and distended small intestines on abdominal palpation per rectum. Abdominal exploratory surgery was performed on both horses. In each instance, small intestine was found to be strangulated by components of the spermatic cord. Both horses were euthanatized because of a poor prognosis. Although not commonly observed, incarceration of intestine by components of the spermatic cord should be considered as a cause of small intestine strangulation in male horses. Early recognition of this ...
Suspected blue canary grass (Phalaris coerulescens) poisoning of horses.
Australian veterinary journal    September 24, 1999   Volume 77, Issue 8 537-538 doi: 10.1111/avj.1999.77.8.537
Colegate SM, Anderton N, Edgar J, Bourke CA, Oram RN.No abstract available
Nonsurgical management of type II fractures of the distal phalanx in 48 standardbred horses.
Australian veterinary journal    September 24, 1999   Volume 77, Issue 8 501-503 doi: 10.1111/j.1751-0813.1999.tb12118.x
O'Sullivan CB, Dart AJ, Malikides N, Rawlinson RJ, Hutchins DR, Hodgson DR.To evaluate nonsurgical management of type II fractures of the distal phalanx in Standardbred horses. Methods: Retrospective study of 48 affected horses. Results: Most fractures occurred on the lateral palmar process of the left forelimb or the medial palmar process of the right forelimb; 81% of horses were considered sound enough to return to training and 63% raced. Of those returning to racing, 41% competed in > 10 races, 37% in 2 to 10 races and 22% in only 1 race. There was no difference in performance before and after fracture. Twenty-four of 25 horses had a bar shoe fitted for > 50...
Primary hypoparathyroidism in two horses.
Australian veterinary journal    September 24, 1999   Volume 77, Issue 8 504-508 doi: 10.1111/j.1751-0813.1999.tb12119.x
Hudson NP, Church DB, Trevena J, Nielsen IL, Major D, Hodgson DR.Two Thoroughbred horses were presented with various clinical signs which included sweating, agitation, muscle twitching and synchronous diaphragmatic flutter. These signs were associated with profound hypocalcaemia. A diagnosis of primary hypoparathyroidism was made on the basis of low serum ionised calcium concentration, hyperphosphataemia and markedly reduced serum immunoreactive parathyroid hormone concentrations in the presence of normal renal function. Treatment with a combination of intravenous calcium and subsequently oral calcium, magnesium and a vitamin D analogue (dihydrotachysterol)...