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Topic:Nervous System

The nervous system in horses is a complex network responsible for transmitting signals between different parts of the body. It consists of the central nervous system (CNS), which includes the brain and spinal cord, and the peripheral nervous system (PNS), which comprises nerves that extend throughout the body. The nervous system regulates various physiological processes, including movement, sensation, and the coordination of bodily functions. It plays a critical role in processing sensory information and initiating appropriate responses. This page compiles peer-reviewed research studies and scholarly articles that explore the structure, function, and clinical implications of the equine nervous system, including its role in behavior, response to stimuli, and neurological disorders.
Neurologic disease induced by equine herpesvirus 1.
Journal of the American Veterinary Medical Association    September 1, 1979   Volume 175, Issue 5 473-474 
Pursell AR, Sangster LT, Byars TD, Divers TJ, Cole JR.No abstract available
Neuritis of the cauda equina, a chronic idiopathic polyradiculoneuritis in the horse.
Acta neuropathologica    April 12, 1979   Volume 46, Issue 1-2 17-24 doi: 10.1007/BF00684799
Cummings JF, de Lahunta A, Timoney JF.Four cases of neuritis of the cauda equina (NCE) were studied by light and electron microscopy. Examination of sacral intradural rootlets revealed inflammatory cell infiltrates and an array of myelinated fiber changes which included myelin stripping by invading mononuclear cells and macrophages, as well as splitting and vesiculation of myelin lamellae without obvious participation by leukocytes. More distally in the extradural roots, there was marked granulomatous inflammation, and demyelinative changes were overshadowed by widespread evidence of irreversible axon damage. In all cases, unusual...
Interaction of seasonal and ovarian factors in the regulation of LH and FSH secretion in the mare.
Journal of reproduction and fertility. Supplement    January 1, 1979   Issue 27 103-111 
Garcia MC, Freedman LJ, Ginther OJ.A working hypothesis for the regulation of LH secretion in the mare is postulated which involves the following two components: (1) a primary central nervous system (CNS)-pituitary component which is responsible for a basal circannual LH rhythm, entrained to an environmental 'Zeitgeber' (most probably photoperiod) and independent of ovarian influences, and (2) a secondary ovarian (steroidal) component which modifies the primary rhythm during the ovulatory season. This hypothesis does not seem to apply in its entirety to FSH secretion; the CNS-pituitary component is demonstrable within the first...
[Structure and topography of the nucleus intermediomedialis in the equine spinal cord].
Polskie archiwum weterynaryjne    January 1, 1979   Volume 22, Issue 1 125-135 
Boratyński Z, Flieger S, Eustachiewicz R, Sławomirski J.In this paper, structure and position of the centers of the parasympathetic nervous system in the horse spinal cord were presented. Studies were carried out on 2 horse spinal cordis. After sampling, the material was dehydrated in alcohol, embedded in paraffin and cut into 15 micron thick sections. The sections were stained according to Nissl's method. Every third section was studied. Nucleus intermediomedialis in the horse spinal cord is an intermittent tract of nervous cells passing from the I cervical neuromere to the V sacral segment. The cells of this nucleus form round, horizontally--oval...
A light and electron microscopic study of the neuropathy of equine idiopathic laryngeal hemiplegia.
Neuropathology and applied neurobiology    November 1, 1978   Volume 4, Issue 6 483-501 doi: 10.1111/j.1365-2990.1978.tb01358.x
Duncan ID, Griffiths IR, Madrid RE.A study has been made of the pathological changes in the recurrent laryngeal nerves from horses with clinical and sub-clinical idiopathic laryngeal hemiplegia. Qualitative and quantitative studies showed in clinical cases there was a progressive distal loss of large myelinated fibres in the left recurrent nerve. Regenerating clusters and onion bulbs were frequently seen in affected nerves both at proximal and distal levels. Degenerating axons were characterized by collections of organelles, and denervated bands of Bungner were common. Similar but less severe changes were seen in the left recur...
Glioarchitecture of the medial lemniscus and pyramids in horses.
Folia morphologica    January 1, 1978   Volume 37, Issue 1 33-43 
Chomiak M, Lakomy M.No abstract available
Horner’s syndrome in large animals.
The Cornell veterinarian    October 1, 1977   Volume 67, Issue 4 529-542 
Smith JS, Mayhew IG.The sympathetic nervous innervation of the head was surgically transected in the horse, cow, sheep and goat. The site of transection was preganglionic in all 4 species and ganglionic-postganglionic in 2 additional horses. The Horner's syndrome, manifested as a result of the iatrogenic lesion, varied with the species. Ptosis was the most constant sign in all species. Unilateral sweating over the face and proximal neck, particularly at the base of the ear, was the most prominent feature in the horse. The cow revealed distension of vasculature and cutaneous heat of the pinna, and a reduced produc...
Disseminated septic meningitis in a mare.
Journal of the American Veterinary Medical Association    September 1, 1977   Volume 171, Issue 5 452-454 
Rumbaugh GE.Physical, neurologic, and clinicopathologic findings in a 3-year-old female Morgan horse with anorexia and nasal discharge suggested suppurative meningitis. Necropsy findings substantiated the tentative diagnosis. Actinomyces sp was cultured from a meningeal abscess surrounding the pituitary gland and from resolving lung abscesses.
Ischemic myelopathy caused by fibrocartilaginous emboli in a horse.
Veterinary pathology    September 1, 1977   Volume 14, Issue 5 479-481 doi: 10.1177/030098587701400507
Taylor HW, Vandevelde M, Firth EC.A horse that suddenly became recumbent had a focal ischemic infarct of the spinal cord between C6 and C7. The infarct was attributed to multiple fibrocartilaginous emboli. Adherence of fibrocartilaginous debris to the outer surface of the dura was interpreted as evidence that intervertebral disc degeneration and displacement of the nucleus pulposus had occurred and that the emboli arose from the disc.
An outbreak of Swainsona poisoning in horses.
Australian veterinary journal    September 1, 1977   Volume 53, Issue 9 446-447 doi: 10.1111/j.1751-0813.1977.tb05496.x
O'Sullivan BM, Goodwin JA.On 6 properties in south-western Queensland an outbreak of nervous disease occurred horses due to ingestion of Swainsonia (Darling pea). Loss of condition, depression, hyperaesthesia and hyperexcitability were seen in affected horses. At autopsy of 2 horses generalised c ytoplasmic vacuolation was seen in the neurones of the central nervous system and in the liver, adrenal and thyroid. The clinical and pathological features were similar to those described in horses suffering from Swainsona poisoning in Australia and Astragalus and Oxytropis in North America.
Epidural melanoma causing posterior paresis in a horse.
Journal of the American Veterinary Medical Association    June 15, 1977   Volume 170, Issue 12 1400-1403 
Traver DS, Moore JN, Thornburg LP, Johnson JH, Coffman JR.An aged gray stallion was examined because of fullminating posterior paresis, bladder paralysis, and perineal anesthesia. Lower motor neuron dysfunction was detected at the lumbosacral level of the spinal cord, and cerebrospinal fluid was yellow. After brief supportive treatment, the horse died. Necropsy revealed a single epidural melanoma at L5-6. The absence of cutaneous melanotic growth, absence of organ involvement, and extensive vertebral remodeling indicated the neoplasm to have been primary and to have been present for an extended period. Neurologic dysfunction was acute and progressive...
Association of Australian arboviruses with nervous disease in horses.
Australian veterinary journal    February 1, 1977   Volume 53, Issue 2 61-66 doi: 10.1111/j.1751-0813.1977.tb14886.x
Gard GP, Marshall ID, Walker KH, Acland HM, Saren WG.An outbreak of Murray Valley encephalitis (MVE) occurred in New South Wales during the first five months of 1974. Specimens from 52 horses with nervous disease collected January to May 1974 were examined histopathological or virologically. Although MVE virus was not isolated, 13 horses had serological evidence of recent infection with MVE virus. Another 4 horses had evidence of recent infection with Ross River virus. Two animals had histological evidence of viral infection of the central nervous system. Attempts to experimentally infect 2 horses with a low dose of MVE virus were not successful...
Micronema deletrix in the central nervous system of a horse.
Journal of the American Veterinary Medical Association    January 15, 1977   Volume 170, Issue 2 175-177 
Powers RD, Benz GW.No abstract available
Equine degenerative myeloencephalopathy.
Journal of the American Veterinary Medical Association    January 15, 1977   Volume 170, Issue 2 195-201 
Mayhew IG, deLahunta A, Whitlock RH, Geary JC.Five horses of mixed breeding and 1 zebra with symmetric tetraparesis and ataxia were studied. There were 2 females and 4 males. Signs of illness were first noticed from birth to 12 months of age. Clinical and pathologic studies were performed when the animals were 4 to 24 months old. Two of the horses were related. All of the subjects had diffuse degenerative myeloencephalopathy. The degeneration was most pronounced in thoracic segments of the spinal cord. Ventral and dorsolateral funiculi were most severely affected. Axonal swelling and abnormal neuronal cell bodies were seen in the gray mat...
Oldest horse brains: more advanced than previously realized.
Science (New York, N.Y.)    November 5, 1976   Volume 194, Issue 4265 626-627 doi: 10.1126/science.790567
Radinsky L.Previous interpretations of early horse brains were based on an incorrectly identified fossil endocast, now believed to be from a condylarth. Newly prepared endocasts of Hyracotherium, the oldest horse and one of the earliest perissodactyls, reveal a relatively larger brain, with a more expanded neocortex, than existed in the condylarth ancestors of perissodactyls. Fifty million years ago, horse brains had suprasylvian, ectolateral, and lateral sulci, but the frontal lobe was undeveloped.
Neuritis of the cauda equina in a horse.
Nordisk veterinaermedicin    September 1, 1976   Volume 28, Issue 9 464-467 
Rimaila-Pärnänen .No abstract available
Leukoencephalomalacia: a mycotoxicosis of Equidae caused by Fusarium moniliforme Sheldon.
The Onderstepoort journal of veterinary research    September 1, 1976   Volume 43, Issue 3 113-122 
Marasas WF, Kellerman TS, Pienaar JG, Naudé TW.When 2 horses were dosed with cultures of a Fusarium moniliforme isolate that had previously caused only hepatosis, 1 developed brain oedema and hepatosis, and the other only leukoencephalomalacia. A 3rd horse developed both leukoencephalomalacia and hepatosis after being dosed with another isolate obtained from maize which was associated with a natural outbreak of the nervous form of the disease. Since leukoencephalomalacia and hepatosis could be induced by the same culture material, it was concluded that both syndromes were manifestations of the same toxicosis. There was also some evidence t...
[Neuritis of the cauda equina in the horse under the electron microscope. Further elucidation of the pathogenesis].
Zentralblatt fur Veterinarmedizin. Reihe A    August 1, 1976   Volume 23, Issue 6 502-519 
Dahme E, Deutschländer N.No abstract available
Encephalitis caused by louping ill virus in a group of horses in Ireland.
Equine veterinary journal    July 1, 1976   Volume 8, Issue 3 113-117 doi: 10.1111/j.2042-3306.1976.tb03311.x
Timoney PJ, Donnelly WJ, Clements LO, Fenlon M.An outbreak of LI infection in a group of free range horses is described. Three of 4 horses displayed signs of CNS disturbance and 2 of these died after illnesses ranging from 2-12 days duration. In both cases a variable degree of viral polioencephalomyelitis was observed. A virus antigenically indistinguishable from a reference strain of LI virus was isolated from the brain and cervical cord of a 3 y.o. draft mare. Serum samples obtained from 3 of the horses contained HI, CF, precipitating and neutralising antibodies to LI virus, with a rise in antibody titre being demonstrated in 2 animals.
Meningeal haemorrhage and congestion associated with the perinatal mortality of foals.
The Veterinary record    June 26, 1976   Volume 98, Issue 26 518-522 doi: 10.1136/vr.98.26.518
Haughey KG, Jones RT.A high frequency of meningeal lesions was found at autopsy in foals dying perinatally. Such lesions are considered an index of injury to the fetal central nervous system, from trauma and/or hypoxia during birth. Their incidence in the sample examined (26 foals) is similar to that observed in the perinatal mortality of lambs and calves.
Observations on the transmission, immunology, clinical signs and chemotherapy of dourine (Trypanosoma equiperdum infection) in horses, with special reference to cerebro-spinal fluid.
The Onderstepoort journal of veterinary research    June 1, 1976   Volume 43, Issue 2 55-66 
Barrowman PR.This paper is a record of observations on the transmission and clinical signs of dourine in naturally infected cases of known duration, and of temporal and quantitative aspects of the immune response in blood and cerebro-spinal fluid. Included in the record are observations on the presence of Trypanosoma equiperdum parasites in these body fluids and methods for their detection. There is evidence that the occurrence of nervous symptoms and lesions in infected horses is associated with the presence of Trypanosoma equiperdum parasites in cerebro-spinal fluid. The suitability of cerebro-spinal flu...
A technique for the investigation of the action of drugs on the neuromuscular junction in the intact horse.
The British veterinary journal    March 1, 1976   Volume 132, Issue 2 226-230 doi: 10.1016/s0007-1935(17)34748-6
Jones RS, Prentice DE.No abstract available
[The fine structure of cerebral motor cortex in the horse]. Hummel G.No abstract available
[Sensory and autonomic nervous system of the choledochus of Equus caballus].
Bollettino della Societa italiana di biologia sperimentale    February 28, 1976   Volume 52, Issue 4 218-220 
d'Angelo A, Langella M, de Girolamo G.No abstract available
Palpebral, frontal, and zygomatic nerve blocks for examination of the equine eye.
Veterinary medicine, small animal clinician : VM, SAC    February 1, 1976   Volume 71, Issue 2 187-189 
Manning JP, St Clair LE.No abstract available
Ejaculatory disorders of the stallion.
Journal of reproduction and fertility. Supplement    October 1, 1975   Issue 23 123-128 
Rasbech NO.Ejaculatory disorders of the stallion seem to occur more frequently than hitherto accepted. The condition is manifested differently in individual stallions from normal copulation without ejaculation to an abnormal pattern of copulation without or with occasional ejaculation. The condition is probably caused by a functional disturbance of the nervous mechanism which controls the ejaculatory process, and may be caused by environmental or other factors. Eleven cases of ejaculatory disorders in normal healthy stallions were investigated and three of these animals recovered after simple correction ...
Postnatal changes in total and free thyroxine and triiodothyronine in foal serum.
Journal of reproduction and fertility. Supplement    October 1, 1975   Issue 23 709-715 
Irvine CH, Evans MJ.Total tyhroxine (TT4), free thyroxine (FT4), total triiodothyronine (TT3) and free triiodothyronine (FT3) concentrations in foal umbilical cord blood were respectively 14, 5 7 and 3 times the concentrations of these hormones in adult horse blood. The TT4 levels in foals declined rapidly to reach adult concentrations by Day 16 and FT4 levels declined steadily during the first 3 months of life. Foal TT3 levels rose during the first 10 hr after birth and thereafter declined, although they were still X2-5 higher than adult levels at 3 months of age. Levels of FT3 similarly increased after birth be...
Metaldehyde poisoning in three horses.
Modern veterinary practice    May 1, 1975   Volume 56, Issue 5 336-337 
Harris WF.Three horses exhibited nervous and cardiopulmonary signs after ingestins small amounts of metaldehyde, and 2 died in 3 to 5 hours. A colt given 0.1 mg/kg was similarly affected and died.
Occurrence of nervous-tissue tumors in cattle, horses, cats and dogs.
International journal of cancer    January 15, 1975   Volume 15, Issue 1 39-47 doi: 10.1002/ijc.2910150106
Hayes HM, Priester WA, Pendergrass TW.From 11 North American veterinary university hospitals and clinics, 248 animals were a confirmed diagnosis of nervous-tissue tumor were identified; 7 tumors were found in cattle, 28 in horses, 14 in cats, 199 in dogs, and none in other species. Tumors were divided for analysis into three categories-glial, meningeal, and peripheral nerve. In cattle and horses, all tumors involved peripheral nerves, the risk of which, in horses, reached a plateau at 4-6 years of age and remained constant thereafter. In cats, the tumors were equally distributed among the three tumor categories whereas, in dogs, t...
Spongy degeneration in the central nervous system of domestic animals. Part III: Occurrence and pathogenesis hepatocerebral disease caused by hyperammonaemia.
Acta neuropathologica    January 1, 1975   Volume 31, Issue 4 343-351 doi: 10.1007/BF00687929
Hooper PT.Severe spongy degeneration of the central nervous system (CNS) was seen in 11 cattle, 19 sheep, 4 pigs and 1 goat, associated with a variety of hepatic diseases, particularly those caused by hepatotoxic pyrrolizidine alkaloids. It was also seen in a milder form in 2 of 8 horses examined, 1 dog of 5 dogs examined, and in 1 rabbit only of a large number of laboratory animals examined. This paper reports results of experiments which confirmed initially that the CNS disease cold be caused by pyrrolizidine alkaloid intoxication. This was done by poisoning lambs with lasiocarpine. As the disease was...