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Topic:Performance Horses

Performance horses are equines specifically trained and conditioned for activities that require a high level of athleticism, such as racing, dressage, show jumping, and eventing. These horses undergo specialized training regimens to enhance their physical capabilities, including speed, endurance, agility, and strength. The management of performance horses often involves tailored nutrition plans, regular veterinary care, and specific conditioning programs to optimize their performance and minimize the risk of injury. This topic covers peer-reviewed research studies and scholarly articles that explore the physiology, training methodologies, health management, and performance outcomes of these horses in various competitive disciplines.
Evaluation of cardiac troponin I, atrial natriuretic peptide and some oxidative/antioxidative biomarkers in the serum and hemolysate of trained Arabian horses after exercise.
Iranian journal of veterinary research    November 13, 2020   Volume 21, Issue 3 211-215 
Pourmohammad R, Mohri M, Seifi HA, Sardari K.Limited information existed on performance tests in Iranian Arab horses. Objective: The objective of this study is to investigate time related changes of cardiac troponin I (cTnI), atrial natriuretic peptide (ANP) and oxidative/antioxidant biomarkers in the serum of Arabian horses before and after regular training. Methods: Blood samples were collected from jugular vein of 25 Arabian horses before exercise; 5 h and 18 h after exercise and used to measure the cTnI, ANP, malondialdehyde (MDA), ferric reducing antioxidant power (FRAP), glutathione peroxidase (GPX), and superoxide dismutase (SOD) ...
Hypercapnia and hyperlactatemia were positively associated with higher-grade arrhythmias during peak exercise in horses during poor performance evaluation on a high-speed treadmill.
Veterinary journal (London, England : 1997)    November 9, 2020   Volume 266 105572 doi: 10.1016/j.tvjl.2020.105572
Reef VB, Davidson EJ, Slack J, Stefanovski D.Cardiac arrhythmias are common in horses during exercise, especially immediately post-exercise. The objectives of this study were to: (1) describe the frequency and type of cardiac arrhythmias detected in horses during incremental high-speed treadmill exercise testing (ITET); (2) determine if arterial blood gas (ABG) changes at peak and immediately post-exercise were associated with arrhythmias; and (3) determine whether upper or lower airway disease was associated with exercising cardiac arrhythmias. Horses (n = 368) presenting for an ITET underwent resting and exercising upper airway endosco...
The effect of serial administration of bicarbonate on plasma total CO2 concentrations in horses.
Drug testing and analysis    November 8, 2020   Volume 13, Issue 2 397-403 doi: 10.1002/dta.2937
Bailey SR, Forbes G, Selvadurai N, McLarney K, Jones S, Steel CM.The administration of alkalinising agents including bicarbonate is of concern to racing authorities because resultant alkalosis may enhance performance and interfere with the detection of drugs in post-race urine. A threshold for total carbon dioxide (TCO ) of 36.0 mmol/L in plasma (with action limit of 37.0 mmol/L) has been set. Serial dosing of sodium bicarbonate has gained popularity in human athletes but has not been studied in horses previously. Sodium bicarbonate (200 g per horse) and 60 g of an electrolyte-vitamin complex was administered in 2-L water via nasogastric intubation to five ...
Exercise-associated rhythm disturbances in poorly performing Thoroughbreds: risk factors and association with racing performance.
Equine veterinary journal    October 29, 2020   Volume 53, Issue 4 656-669 doi: 10.1111/evj.13354
Marr CM, Franklin S, Garrod G, Wylie C, Smith L, Dukes-McEwan J, Bright J, Allen K.Exercise-associated cardiac rhythm disturbances are common, but there is a lack of evidence-based criteria on which to distinguish clinically relevant rhythm disturbances from those that are not. Objective: To describe and characterise rhythm disturbances during clinical exercise testing; to explore potential risk factors for these rhythm disturbances and to determine whether they influenced future racing. Methods: Retrospective cohort using a convenience sample. Methods: Medical records were reviewed from two clinical services to identify horses with poor performance and/or respiratory noise ...
Unravelling androgens in sport: Altrenogest shows strong activation of the androgen receptor in a mammalian cell bioassay.
Drug testing and analysis    October 26, 2020   Volume 13, Issue 3 523-528 doi: 10.1002/dta.2941
Gillon A, Ho ENM, Chan GHM, Kauff A, Hughes G, Lund RA, Ashley Z, Wan TSM, Heather AK.Altrenogest is a commonly used progestogen for the suppression of oestrus and associated distracting behaviours that interfere with training and performance of female racehorses. The steroid is derived from 19-nor testosterone and is structurally similar to the anabolic androgenic steroid, trenbolone. In this study, the relative androgen potency of altrenogest was determined by a kidney (HEK293) cell androgen bioassay. The HEK293 bioassay shows that in its pure form, altrenogest has a high relative potency compared with testosterone but is not as strong as β-trenbolone. Our results also show ...
A Survey of Clinical Usage of Non-steroidal Intra-Articular Therapeutics by Equine Practitioners.
Frontiers in veterinary science    October 22, 2020   Volume 7 579967 doi: 10.3389/fvets.2020.579967
Velloso Alvarez A, Boone LH, Braim AP, Taintor JS, Caldwell F, Wright JC, Wooldridge AA.There are several non-steroidal intra-articular therapeutics (NSIATs) available for use by equine practitioners for the treatment of performance-limiting joint-related pathology. Information is limited on perceived clinical efficacy, recommended treatment protocols, and associated complications. Our objective with this cross-sectional survey was to investigate the current clinical usage of NSIATs by equine practitioners. An electronic cross-sectional convenience survey inquiring about the use of steroidal and NSIATS (platelet-rich plasma, autologous conditioned serum, autologous protein soluti...
Effect of a Half Pad on Pressure Distribution in Sitting Trot and Canter Beneath a Saddle Fitted to Industry Guidelines.
Journal of equine veterinary science    October 17, 2020   Volume 96 103307 doi: 10.1016/j.jevs.2020.103307
MacKechnie-Guire R, Fisher M, Pfau T.Using a half pad beneath a saddle can be beneficial for improving saddle fit. However, there is a paucity of evidence on half pad use when used beneath a correctly fitted saddle. The aim was to quantify the effect that three different half pads have on pressure distribution beneath a saddle fitted following industry guidelines. Twelve nonlame horses were ridden by experienced riders in sitting trot and canter on each rein (three repeats). Saddle fit, with a high-withered cotton saddle cloth (control) compared with three half pads (viscoelastic gel, wool, and medical-grade, closed-cell foam), w...
A duplex qPCR assay for human erythropoietin (EPO) transgene to control gene doping in horses.
Drug testing and analysis    October 14, 2020   Volume 13, Issue 1 113-121 doi: 10.1002/dta.2907
Cheung HW, Wong KS, Lin VYC, Wan TSM, Ho ENM.The misuse of genetic manipulation technology to enhance athletic performance is termed gene doping which is prohibited in human sports, horseracing, and equestrian sports. Although many qPCR assays have been developed, most assays employ genomic DNA (gDNA) from humans, non-human primates, and mice as a background and they may not be applicable for testing horse samples. This study aimed to develop a qPCR assay for the detection of human erythropoietin (hEPO) transgene in horse blood cells where the viral vectors used in gene therapy can reside for months. For the detection of hEPO transgene, ...
Irregular hearts and performance horses.
Equine veterinary journal    October 6, 2020   Volume 52, Issue 6 782-786 doi: 10.1111/evj.13316
Physick-Sheard PW, Slack J.No abstract available
A Systematic Review and Meta-analysis on Sodium Bicarbonate Administration and Equine Running Performance: Is it Time to Stop Horsing Around With Baking Soda?
Journal of equine veterinary science    October 6, 2020   Volume 95 103281 doi: 10.1016/j.jevs.2020.103281
Denham J, Hulme A.Sodium bicarbonate administration in the hours prior to exercise has been used as a performance-enhancing substance in horses since the late 1980s. Although sodium bicarbonate administration to racehorses 24 hours before racing is a banned practice in most racing industries, whether or not it improves running performance in racehorses is currently unclear. The aim of this systematic review and meta-analysis was to establish whether or not acute sodium bicarbonate administration improves running performance in trained Standardbred and Thoroughbred horses. Seven randomized controlled trials, in...
Comparing racing performance following arthroscopic surgery of metacarpophalangeal/metatarsophalangeal and carpal joints in Thoroughbred racehorses rehabilitated using conventional and underwater treadmill therapies.
The Veterinary record    September 23, 2020   Volume 187, Issue 9 355 doi: 10.1136/vr.105745
Potenza KN, Huggons NA, Jones ARE, Rosanowski SM, McIlwraith CW.Rehabilitation of horses using underwater treadmill therapy has been shown to improve joint range of motion, joint mobility, stride length and proprioceptive parameters with experimental studies. However, studies investigating the prognosis and return to function following rehabilitation are lacking. Methods: A retrospective study of Thoroughbred racehorses treated with arthroscopic surgery for osteochondral fragments of the metacarpophalangeal (MCP) or metatarsophalangeal (MTP) joints or carpal joints undergoing conventional rehabilitation or underwater treadmill assisted rehabilitation at th...
Medicine in the Sport of Horse Racing.
Current sports medicine reports    September 15, 2020   Volume 19, Issue 9 373-379 doi: 10.1249/JSR.0000000000000750
Ryan KD, Brodine J, Pothast J, McGoldrick A.Horseracing is among the most popular and increasingly lucrative industry sports in the nation. The average jockey must control a thoroughbred horse 10 times their weight that may act unpredictably whether at rest or full gallop resulting in falls, kicks, or even biting injuries. Despite the risks, jockeys do not have access to the same quality of medical care that is standard in similarly profitable sports organizations. Beyond the mental and physical demands of training and performance endured by any professional athlete, jockeys are confronted with health challenges unique to their sport. I...
The Impact of Horse Age, Sex, and Number of Riders on Horse Performance in British Eventing Horse Trials.
Journal of equine veterinary science    September 14, 2020   Volume 94 103250 doi: 10.1016/j.jevs.2020.103250
Hanousek K, Salavati M, Dunkel B.Limited research has been undertaken to determine the impact of horse age, sex, and number of riders on horse performance in British Eventing (BE) horse trials. Improved understanding of this can aid professionals in planning a competition horse's career. To investigate the impact of age, sex, and number of riders on the peak performance of horses at each of the main levels of BE competitions. The best score from each horse competing in BE horse trials in the years 2008-2018 was recorded, and principal component and hierarchical cluster analysis was performed. Basic data analysis was used to i...
Venous Blood Acid-Base Status in Show Jumper Horses Subjected to Different Physical Exercises.
Journal of equine veterinary science    September 12, 2020   Volume 94 103251 doi: 10.1016/j.jevs.2020.103251
Arfuso F, Giannetto C, Giudice E, Fazio F, Panzera F, Piccione G.The aim of this study was to assess whether acid-base profile exhibits changes in regularly trained show jumping horses undergoing increasing exercise workloads. Seven female Italian saddle horses were subjected to three different physical exercise trials of increasing workload identified as three exercise phases (EPs). During EPI horses were subjected to a standardized exercise test consisting of 15 minutes of treadmill, during EPII horses were subjected to a show jumping test (height, 0.9-1.1 m; course length, 300 m), during EPIII horses underwent two jumping sessions carried out over two...
Microdamage in the equine superficial digital flexor tendon.
Equine veterinary journal    September 2, 2020   Volume 53, Issue 3 417-430 doi: 10.1111/evj.13331
O'Brien C, Marr N, Thorpe C.The forelimb superficial digital flexor tendon (SDFT) is an energy-storing tendon that is highly susceptible to injury during activities such as galloping and jumping, such that it is one of the most commonly reported causes of lameness in the performance horse. This review outlines the biomechanical and biothermal effects of strain on the SDFT and how these contribute to the accumulation of microdamage. The effect of age-related alterations on strain response and subsequent injury risk is also considered. Given that tendon is a slowly healing and poorly regenerative tissue, prompt detection o...
Static pelvic posture is not related to dynamic pelvic tilt or competition level in dressage riders.
Sports biomechanics    August 19, 2020   Volume 22, Issue 10 1290-1302 doi: 10.1080/14763141.2020.1797150
Wilkins CA, Nankervis K, Protheroe L, Draper SB.Static assessment and grouping of riders by competition level are prevalent in equestrian coaching practice and research. This study explored sagittal pelvic tilt in 35 competitive dressage riders to analyse the relationship between static and dynamic postures and assess the interaction of competition level. Riders were assessed using optical motion capture on a riding simulator at halt and in walk, trot, and left and right canter. Mean, minimum and maximum pelvic tilt, and range of motion (ROM) were measured as the pitch rotation of a rigid body formed by markers placed on the rider's left/ri...
Muscle modes of the equestrian rider at walk, rising trot and canter.
PloS one    August 18, 2020   Volume 15, Issue 8 e0237727 doi: 10.1371/journal.pone.0237727
Elmeua González M, Šarabon N.Equestrian sports have been a source of numerous studies throughout the past two decades, however, few scientists have focused on the biomechanical effects, including muscle activation, that the horse has on the rider. Because equitation is a sport of two (the horse-human dyad), we believe there is a need to fill in the knowledge gap in human biomechanics during riding. To investigate the differences between novice and advanced riders at a neuromuscular level we characterized the motor output of a set of riders' key muscles during horse riding. Six recreational riders (24 ± 7 years) and nine ...
Doping control analysis of GW1516 in equine plasma using liquid chromatography/electrospray ionization Q-Exactive high-resolution mass spectrometry.
Rapid communications in mass spectrometry : RCM    August 11, 2020   Volume 34, Issue 23 e8920 doi: 10.1002/rcm.8920
Ishii H, Leung GN, Yamashita S, Yamada M, Kushiro A, Kasashima Y, Okada J, Kawasaki K, Kijima-Suda I.GW1516 is a peroxisome proliferator-activated receptor-δ agonist in the class of hormones and metabolic modulators. The use of GW1516 is banned in both horseracing and equestrian competitions. To the best of our knowledge, this is the first metabolic study of GW1516 in horses. Methods: After protein precipitation of pre- and post-administration plasma GW1516 samples, the supernatants were analyzed using liquid chromatography/electrospray ionization Q-Exactive high-resolution mass spectrometry to detect GW1516 and its metabolites. Monoisotopic ions of GW1516 and its metabolites were monitored ...
Affecting Lipid Metabolism Salivary MicroRNAs Expressions in Arabian Racehorses Before and After the Race.
Journal of equine veterinary science    August 8, 2020   Volume 93 103218 doi: 10.1016/j.jevs.2020.103218
Ekici S, Ozmen O.The active roles of microribonucleic acids (miRNAs) in gene regulation have made miRNAs a key point for the scientific world in the study of physiological processes. Although saliva includes the largest number of miRNAs, there is no miRNA study in saliva on horses has been found. Our study is the first study on miRNAs isolation from saliva in horses. In the present study, saliva was studied in Arabian racehorses to better understand the molecular mechanisms of expression levels that are effective in lipid metabolism of miRNAs and their target genes during the race. Identification of lipid meta...
Variation in the SLC16A1 and the ACOX1 Genes Is Associated with Gallop Racing Performance in Arabian Horses.
Journal of equine veterinary science    August 5, 2020   Volume 93 103202 doi: 10.1016/j.jevs.2020.103202
Fontanel M, Todd E, Drabbe A, Ropka-Molik K, Stefaniuk-Szmukier M, Myćka G, Velie BD.Arabian horses are not only one of the most ancient breeds in the world, but they are also one of the most appreciated racehorse breeds today. The breed generates attention for their phenomenal endurance ability and their capability for gallop racing. Consequently, genetic testing to select the best individuals is attracting ever increasing interests from the Arabian industry. As such, the aim of this study was to further investigate associations between performance and variation at candidate genes suspected of having a key role in Arabian gallop racing performance. Generalized linear models w...
The Effect of Stirrup Iron Style on Normal Forces and Rider Position.
Journal of equine veterinary science    August 4, 2020   Volume 94 103203 doi: 10.1016/j.jevs.2020.103203
Stapley ED, Stutzman BE, Manfredi JM.The stirrup iron has the potential to modify the forces experienced by a horse and rider during ridden exercise. A range of stirrup designs are available, but no previous studies have investigated if these modifications influence riders' position and interaction with the horse. Novel flexible (F) or flexible and rotatable (FR) irons versus traditional (T) stirrups may positively impact the welfare and performance of the horse and rider. Four riders rode using the three stirrup types (T, F, and FR). Hip, knee, and ankle angles and toe position from film, and the normal force exerted bilaterally...
Physiological Demands of Professional Flat and Jump Horse Racing.
Journal of strength and conditioning research    August 1, 2020   Volume 34, Issue 8 2173-2177 doi: 10.1519/JSC.0000000000003677
Kiely M, Warrington GD, McGoldrick A, Pugh J, Cullen S.Kiely, M, Warrington, GD, McGoldrick, A, Pugh, J, and Cullen, S. Physiological demands of professional flat and jump horse racing. J Strength Cond Res 34(8): 2173-2177, 2020-No information is currently available on the effect of race distance on the physiological demands of jockeys. This study aimed to quantify the respective demands of short and long flat and jump race distances. Twenty professional jockeys (10 flat and 10 jump) participated in the study. The subjects initially performed a graded incremental exercise test to volitional exhaustion on a treadmill to determine the peak heart rat...
Effects of High Intensity Laser Therapy in the Treatment of Tendon and Ligament Injuries in Performance Horses.
Animals : an open access journal from MDPI    July 31, 2020   Volume 10, Issue 8 doi: 10.3390/ani10081327
Zielińska P, Nicpoń J, Kiełbowicz Z, Soroko M, Dudek K, Zaborski D.The aim of this study was to evaluate the effects of high intensity laser therapy (HILT) on tendon and ligament injury treatment in horses. Twenty six horses with tendinopathies were randomly assigned to a HILT treated or to a non-treated group. Each horse was subjected to the same rehabilitation programme. Horses from the treatment group underwent a series of fifteen HILT treatments with the same parameters. Clinical and ultrasound assessments were performed by the same veterinarian and were carried out before (day 0), during (day 13-15) and after treatment (day 38-40). Clinical evaluation in...
Exome analysis and functional classification of identified variants in racing Quarter Horses.
Animal genetics    July 21, 2020   Volume 51, Issue 5 716-721 doi: 10.1111/age.12976
Curi RA, Pereira GL, Alvarez MVN, Baldassini WA, Machado Neto OR, Chardulo LAL.The main objectives of this study were to identify and functionally classify SNPs and indels by exome sequencing of animals of the racing line of Quarter Horses. Based on the individual genomic estimated breeding values (GEBVs) for maximum speed index (SImax) obtained for 349 animals, two groups of 20 extreme animals were formed. Of these individuals, 20 animals with high GEBVs for SImax and 19 with low GEBVs for SImax had their exons and 5' and 3' UTRs sequenced. Considering SNPs and indels, 105 182 variants were identified in the expressed regions of the Quarter Horse genome. Of these, 72 ...
Arthroscopic debridement of short frontal plane proximal phalanx fractures preserves racing performance.
Equine veterinary journal    July 18, 2020   Volume 53, Issue 2 267-276 doi: 10.1111/evj.13275
Elzer EJ, Bramlage LR.Outcomes have been reported for a limited number of short frontal plane fractures of the proximal phalanx following nonsurgical treatment and internal fixation. Objective: To describe a new approach, arthroscopic debridement, of short frontal plane fractures of the proximal phalanx in flat-racing Thoroughbreds and post-operative racing outcome. Methods: Retrospective case-control study. Methods: Medical records of 81 Thoroughbred racehorses treated with arthroscopic debridement for frontal plane fractures of the proximal phalanx were reviewed. Diagnostic images and operative reports were used ...
Postinjury performance for differing humeral stress fracture locations in the racing thoroughbred.
Veterinary surgery : VS    July 17, 2020   Volume 49, Issue 7 1412-1417 doi: 10.1111/vsu.13447
Henderson B, Bramlage LR, Koenig J, Monteith G.To assess the influence of humeral stress fracture location on the time to return to racing and postinjury performance of thoroughbred racehorses. Methods: Retrospective study (1992-2015). Methods: Thoroughbred racehorses (n = 131) that presented for lameness with the sole diagnosis of humeral stress fractures in the lame limb, as determined by scintigraphy or radiology. Methods: Sex, fracture site, age, starts, earnings, and average earnings per race were examined for differences in pre-stress and post-stress fracture diagnosis for the entire population as well as individual stress fracture l...
Detection of bioactive peptides including gonadotrophin-releasing factors (GnRHs) in horse urine using ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC/HRMS).
Drug testing and analysis    July 17, 2020   Volume 12, Issue 9 1274-1286 doi: 10.1002/dta.2880
Kwok KY, Choi TLS, Kwok WH, Lau MY, Leung EMK, Leung GNW, Wong JKY, Wan TSM, Adrian FF, Prabhu A, Ho ENM.The use of bioactive peptides as a doping agent in both human and animal sports has become increasingly popular in recent years. As such, methods to control the misuse of bioactive peptides in equine sports have received attention. This paper describes a sensitive accurate mass method for the detection of 40 bioactive peptides and two non-peptide growth hormone secretagogues (< 2 kDa) at low pg/mL levels in horse urine using ultra-high performance liquid chromatography-high resolution mass spectrometry (UHPLC/HRMS). A simple mixed-mode cation exchange solid-phase extraction (SPE) cartridge was...
Application of a non-target variable data independent workflow (vDIA) for the screening of prohibited substances in doping control testing.
Drug testing and analysis    July 15, 2020   Volume 13, Issue 5 1008-1033 doi: 10.1002/dta.2881
Leung DKK, Wong ASY, Zhou QL, Wan TSM, Ho ENM.A non-target variable Data Independent Acquisition (vDIA) workflow based on accurate mass measurements using a Q Exactive OrbiTrap is presented for the first time for equine doping control testing. The vDIA workflow uses a combination of MS1 events (1 to 2) and multiple vDIA events to cover the analytes of interest. The workflow basically captures a digital image of a sample allowing all relevant MS1 and MS2 data to be recorded. In theory, the workflow can accommodate an unlimited number of analytes as long as they are amenable to the sample extraction protocol and fall within the mass limits ...
Next-Generation Sequencing in Equine Genomics.
The Veterinary clinics of North America. Equine practice    July 14, 2020   Volume 36, Issue 2 195-209 doi: 10.1016/j.cveq.2020.03.002
Petersen JL, Coleman SJ.The sequencing and assembly of a reference genome for the horse has been revolutionary for investigation of horse health and performance. Next-generation sequencing (NGS) methods represent a second revolution in equine genomics. Researchers can align and compare DNA and RNA sequencing data to the reference genome to explore variation that may contribute or be attributed to disease. NGS has also facilitated the translation of research discovery to clinically relevant applications. This article discusses the history and development of NGS, details some of the available sequencing platforms, and ...
Effects of endurance racing on horse plasma extracellular particle miRNA.
Equine veterinary journal    July 1, 2020   Volume 53, Issue 3 618-627 doi: 10.1111/evj.13300
de Oliveira GP, Porto WF, Palu CC, Pereira LM, Reis AMM, Marçola TG, Teixeira-Neto AR, Franco OL, Pereira RW.Physical exercise is an essential factor in preventing and treating metabolic diseases by promoting systemic benefits throughout the body. The molecular factors involved in this process are poorly understood. Micro RNAs (miRNAs) are small non-coding RNAs that inhibit mRNA transcription. MiRNAs, which can participate in the benefits of exercise to health, circulate in plasma in extracellular particles (EP). Horses that undergo endurance racing are an excellent model to study the impact of long-duration/low intensity exercise in plasma EP miRNAs. Objective: To evaluate the effects of 160 km end...
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