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Topic:Risk Factors

Risk factors in horses refer to variables or conditions that increase the likelihood of disease, injury, or other adverse health outcomes in equine populations. These factors can be intrinsic, such as age, breed, and genetic predisposition, or extrinsic, including environmental conditions, management practices, and exposure to infectious agents. Understanding risk factors is important for developing preventive strategies and improving health management in horses. This page aggregates peer-reviewed research studies and scholarly articles that explore the identification, assessment, and mitigation of risk factors in equine health, with the aim of enhancing disease prevention and promoting overall well-being in horses.
Risk factors for recurrence of atrial fibrillation in horses after cardioversion to sinus rhythm.
Journal of veterinary internal medicine    April 27, 2015   Volume 29, Issue 3 946-953 doi: 10.1111/jvim.12606
Decloedt A, Schwarzwald CC, De Clercq D, Van Der Vekens N, Pardon B, Reef VB, van Loon G.Although atrial fibrillation (AF) can be successfully treated in horses, recurrence occurs frequently. In humans, atrial function after cardioversion can predict recurrence. Objective: To examine the prognostic value of atrial mechanical function at 24 hours after cardioversion and other potential predictor variables for AF recurrence in horses. Methods: 117 horses treated for AF at 4 referral centers. Methods: Retrospective study. Inclusion criteria were successful cardioversion, echocardiography at 24 hours after cardioversion and ≥4 months follow-up. To determine factors associated with A...
Animal-related activities as risk factors for injuries among youth on agricultural operations.
Journal of agromedicine    April 24, 2015   Volume 20, Issue 2 188-194 doi: 10.1080/1059924X.2015.1010058
Ryan AD, Gerberich SG, Alexander BH, Renier CM.Working with animals on agricultural operations is hazardous for youths. This study evaluated the associations between activities and injuries related to specific animal types. A case-control study within the Regional Rural Injury Study II included 425 youths (less than 20 years of age) with injuries related to their operation and 1,886 controls (randomly selected youths). Exposures of interest were collected for the months prior to injury events for cases and randomly selected months for controls, based on an injury incidence algorithm. Multivariate logistic regression characterized associati...
Seroprevalence and Potential Risk Factors Associated with Neospora spp. Infection among Asymptomatic Horses in Jordan.
The Korean journal of parasitology    April 22, 2015   Volume 53, Issue 2 163-167 doi: 10.3347/kjp.2015.53.2.163
Talafha AQ, Abutarbush SM, Rutley DL.This study aimed to determine the seroprevalence and to identify risk factors associated with Neospora spp. infection in horses in Jordan. Management related data were collected from each farm and individual horses. Sera from 227 horses from 5 of 6 climatic regions in Jordan were analyzed for the presence of antibodies to Neospora spp. by ELISA kit. The study was performed during spring of 2010. The association between seropositivity and risk factors was analyzed. A total of 7 (3%) of 227 sera had antibodies for Neospora spp. There was a significant regional difference (P=0.018) between the 5 ...
Serological evidence of equine influenza infections among persons with horse exposure, Iowa.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology    April 9, 2015   Volume 67 78-83 doi: 10.1016/j.jcv.2015.04.009
Larson KR, Heil GL, Chambers TM, Capuano A, White SK, Gray GC.Equine influenza virus (EIV) is considered enzootic in North America and experimental studies have documented human EIV infections. Methods: This cross-sectional study examined 94 horse-exposed and 34 non-exposed controls for serological evidence of EIV infection. Sera were evaluated for antibodies against three EIV and two human H3N2 viruses using microneutralization (MN), neuraminidase inhibition (NI), enzyme-linked lectin (ELLA), and hemagglutination inhibition (HI) serological assays. Risk factor analyses were conducted using logistic regression and proportional odds modeling. Results: The...
Risk factors for epistaxis in jump racing in Great Britain (2001-2009).
Veterinary journal (London, England : 1997)    April 9, 2015   Volume 205, Issue 1 44-49 doi: 10.1016/j.tvjl.2015.04.003
Reardon RJ, Boden LA, Mellor DJ, Love S, Newton RJ, Stirk AJ, Parkin TD.The aim of this study was to evaluate risk factors associated with developing epistaxis in jump racing in Great Britain (GB). A retrospective analysis of records from horses running in all hurdle and steeplechase races in GB between 2001 and 2009 identified diagnoses of epistaxis whilst still at the racecourse. Data were used from 603 starts resulting in epistaxis (event) and 169,065 starts resulting in no epistaxis (non-event) in hurdle racing, and from 550 event starts and 102,344 non-event starts in steeplechase racing. Two multivariable logistic regression models to evaluate risk factors a...
Update on exercise-induced pulmonary hemorrhage.
The Veterinary clinics of North America. Equine practice    March 15, 2015   Volume 31, Issue 1 187-198 doi: 10.1016/j.cveq.2014.11.011
Sullivan S, Hinchcliff K.Exercise-induced pulmonary hemorrhage (EIPH) is an important disease of horses that perform high-intensity athletic activity. EIPH is an ongoing concern for the racing industry because of its high prevalence; potential impact on performance; welfare concerns; and use of prophylactic medications, such as furosemide, on race day. During the last 10 years, significant progress has been made in understanding the pathogenesis and risk factors for EIPH and the impact of the disease on performance and career. This article summarizes the most recent advances in EIPH.
Nonstrangulating intestinal infarction associated with Strongylus vulgaris in referred Danish equine cases.
Equine veterinary journal    March 12, 2015   Volume 48, Issue 3 376-379 doi: 10.1111/evj.12422
Nielsen MK, Jacobsen S, Olsen SN, Bousquet E, Pihl T.Strongylus vulgaris is a pathogenic helminth parasite infecting horses and was once considered to be the primary cause of colic. Migrating larvae cause ischaemia and infarction of intestinal segments. This knowledge is derived from case reports and experimental inoculations of parasite-naïve foals, and it remains unknown to what extent the parasite is associated with different types of colic. Objective: To evaluate the role of S. vulgaris as a risk factor for different types of colic in horses. Methods: A retrospective case-control study among horses referred with abdominal pain to the Univ...
Science in brief: recent advances into understanding tendon function and injury risk.
Equine veterinary journal    February 4, 2015   Volume 47, Issue 2 137-140 doi: 10.1111/evj.12346
Thorpe CT, Spiesz EM, Chaudhry S, Screen HR, Clegg PD.No abstract available
Assessing the seasonal prevalence and risk factors for nuchal crest adiposity in domestic horses and ponies using the Cresty Neck Score.
BMC veterinary research    January 31, 2015   Volume 11 13 doi: 10.1186/s12917-015-0327-7
Giles SL, Nicol CJ, Rands SA, Harris PA.Nuchal crest adiposity in horses and ponies has been associated with an enhanced risk of metabolic health problems. However, there is no current information on the prevalence of, and risk factors specific to, nuchal crest adiposity in horses and ponies. In addition, the cresty neck score has not previously been utilised across different seasons within a UK leisure population, it is not know whether nuchal crest adiposity shows the same seasonal trends as general obesity. Results: A Cresty Neck Score (CNS, 0-5) was given to 96 horses with access to pasture (>6 h per day) at the end of winter a...
Clinical features and management of equine post operative ileus: Survey of diplomates of the European Colleges of Equine Internal Medicine (ECEIM) and Veterinary Surgeons (ECVS).
Equine veterinary journal    January 12, 2015   Volume 48, Issue 2 182-187 doi: 10.1111/evj.12355
Lefebvre D, Pirie RS, Handel IG, Tremaine WH, Hudson NP.There is a need for an improved understanding of equine post operative ileus (POI), in terms of both clinical definition and optimal management. Although the pharmacological strategies that are used to treat POI continue to evolve, little is known about the supplementary strategies used to prevent and manage this condition. Objective: To report the current strategies used to diagnose, prevent and manage POI following emergency abdominal surgeries. Methods: Cross-sectional survey. Methods: An electronic survey invitation was sent by email to 306 European college diplomates (European Colleges of...
Risk factors associated with the transmission of Brazilian spotted fever in the Piracicaba river basin, State of São Paulo, Brazil.
Revista da Sociedade Brasileira de Medicina Tropical    January 1, 2015   Volume 48, Issue 1 11-17 doi: 10.1590/0037-8682-0281-2014
Souza CE, Pinter A, Donalisio MR.Brazilian spotted fever (BSF) is a disease transmitted by ticks for which the etiological agent is Rickettsia rickettsii. The present essay evaluates the risk factors associated with the transmission of cases of BSF in the time period between 2003 and 2013 in the Piracicaba river basin, state of São Paulo. Methods: This essay presents a retrospective study to identify the factors associated with the transmission of cases of BSF among all suspected cases identified by the System for Epidemiological Surveillance of São Paulo (CVE). After the description of temporal distribution (onset of sympt...
Prevalence, location and symmetry of noncatastrophic ligamentous suspensory apparatus lesions in California Thoroughbred racehorses, and association of these lesions with catastrophic injuries.
Equine veterinary journal    December 14, 2014   Volume 48, Issue 1 27-32 doi: 10.1111/evj.12367
Hill AE, Gardner IA, Carpenter TE, Lee CM, Hitchens PL, Stover SM.Knowledge of the site distribution of ligamentous injuries facilitates clinical diagnosis of suspensory apparatus conditions. Objective: To determine if lesions within the suspensory ligament (SL) and distal ligaments of the proximal sesamoid bones (DSLs) were associated with suspensory apparatus failure or metacarpal lateral condylar fracture in California Thoroughbred racehorses. Methods: Cross-sectional study. Methods: Suspensory apparatus specimens from 327 deceased Thoroughbred racehorses were sectioned within the SL body and branches, and oblique and straight DSLs. Purple lesions ≥2 ...
Duration of disease influences survival to discharge of Thoroughbred mares with surgically treated large colon volvulus.
Equine veterinary journal    December 14, 2014   Volume 47, Issue 6 650-654 doi: 10.1111/evj.12358
Hackett ES, Embertson RM, Hopper SA, Woodie JB, Ruggles AJ.Large colon volvulus results in strangulating obstruction requiring surgical treatment. Duration of this disease prior to surgical treatment is likely to influence survival directly. Objective: The primary objective of this study was to evaluate the influence of duration of large colon volvulus on patient survival to discharge. Relationships between other factors and survival following large colon volvulus were also examined. Methods: Retrospective case analysis. Methods: Medical records of Thoroughbred mares aged ≥2 years undergoing surgical treatment for large colon volvulus between 1 Marc...
Identification of Suitable Areas for African Horse Sickness Virus Infections in Spanish Equine Populations.
Transboundary and emerging diseases    December 5, 2014   Volume 63, Issue 5 564-573 doi: 10.1111/tbed.12302
Sánchez-Matamoros A, Sánchez-Vizcaíno JM, Rodríguez-Prieto V, Iglesias E, Martínez-López B.African horse sickness (AHS) is one of the most important vector-borne viral infectious diseases of equines, transmitted mainly by Culicoides spp. The re-emergence of Culicoides-borne diseases in Europe, such as the recent bluetongue (BT) or Schmallenberg outbreaks, has raised concern about the potential re-introduction and further spread of AHS virus (AHSV) in Europe. Spain has one of the largest European equine populations. In addition, its geographical, environmental and entomological conditions favour AHSV infections, as shown by the historical outbreaks in the 1990s. The establishment of ...
Idiopathic focal eosinophilic enteritis (IFEE), an emerging cause of abdominal pain in horses: the effect of age, time and geographical location on risk.
PloS one    December 2, 2014   Volume 9, Issue 12 e112072 doi: 10.1371/journal.pone.0112072
Archer DC, Costain DA, Sherlock C.Idiopathic focal eosinophilic enteritis (IFEE) is an emerging cause of abdominal pain (colic) in horses that frequently requires surgical intervention to prevent death. The epidemiology of IFEE is poorly understood and it is difficult to diagnose pre-operatively. The aetiology of this condition and methods of possible prevention are currently unknown. The aims of this study were to investigate temporal and spatial heterogeneity in IFEE risk and to ascertain the effect of horse age on risk. Results: A retrospective, nested case-control study was undertaken using data from 85 IFEE cases and 848 ...
Spatial and temporal distribution of West Nile virus in horses in Israel (1997-2013)–from endemic to epidemics.
PloS one    November 17, 2014   Volume 9, Issue 11 e113149 doi: 10.1371/journal.pone.0113149
Aharonson-Raz K, Lichter-Peled A, Tal S, Gelman B, Cohen D, Klement E, Steinman A.With the rapid global spread of West Nile virus (WNV) and the endemic state it has acquired in new geographical areas, we hereby bring a thorough serological investigation of WNV in horses in a longstanding endemic region, such as Israel. This study evaluates the environmental and demographic risk factors for WNV infection in horses and suggests possible factors associated with the transition from endemic to epidemic state. West Nile virus seroprevalence in horses in Israel was determined throughout a period of more than a decade, before (1997) and after (2002 and 2013) the massive West Nile f...
Serosurveillance of infectious agents in equines of the Central Valley of Costa Rica.
Open veterinary journal    November 16, 2014   Volume 4, Issue 2 107-112 
Jiménez D, Romero-Zuñiga JJ, Dolz G.Blood samples from 181 equines from the Central Valley of Costa Rica were collected in the year 2012 to determine the presence of antibodies against selected infectious agents in horses and to determine the risk factors associated with these agents. The presence of antibodies against Equine Infectious Anemia Virus (EIAV), Equine Herpes Virus 1 and 4 (EHV-1 and EHV-4), West Nile Virus (WNV), Influenza A Virus (IAV), Equine Viral Arteritis Virus (EVAV), Babesia caballi, Theileria equi, Neospora caninum and Chlamydia abortus was determined using commercial assays, and risk factors associated with...
Equine protozoal myeloencephalitis.
The Veterinary clinics of North America. Equine practice    November 6, 2014   Volume 30, Issue 3 659-675 doi: 10.1016/j.cveq.2014.08.012
Howe DK, MacKay RJ, Reed SM.Equine protozoal myeloencephalitis (EPM) can be caused by either of 2 related protozoan parasites, Sarcocystis neurona and Neospora hughesi, although S. neurona is the most frequent etiologic pathogen. Horses are commonly infected, but clinical disease occurs infrequently; the factors influencing disease occurrence are not well understood. Risk factors for the development of EPM include the presence of opossums and prior stressful health-related events. Attempts to reproduce EPM experimentally have reliably induced antibody responses in challenged horses but have not consistently produced acut...
Frequency of and risk factors associated with catastrophic musculoskeletal injuries in Quarter Horses at two Midwestern racetracks: 67 cases (2000-2011).
Journal of the American Veterinary Medical Association    October 31, 2014   Volume 245, Issue 10 1160-1168 doi: 10.2460/javma.245.10.1160
Beisser A, McClure S, Rezabek G, Soring KH, Wang C.To determine the incidence and anatomic location of and potential risk factors for catastrophic musculoskeletal injuries (CMIs) in racing Quarter Horses. Methods: Retrospective matched case-control study. Methods: 67 racing Quarter Horse racehorses euthanized because of CMIs and 134 matched controls. Methods: Data for Quarter Horses that sustained CMIs and the total number of race starts for each year were obtained from 2 Midwestern racing jurisdictions from 2000 through 2011. Information for each horse with a CMI and for 2 randomly selected control horses that ran in the same race but did not...
The effect of passively acquired antibodies on Lawsonia intracellularis infection and immunity in the horse.
Equine veterinary journal    October 19, 2014   Volume 47, Issue 6 655-661 doi: 10.1111/evj.12335
Page AE, Stills HF, Horohov DW.Multiple hypotheses into the age-based susceptibility of animals to Lawsonia intracellularis exist, including the decline of passively acquired antibodies. Objective: To determine whether the decline in passively acquired antibodies in horses is responsible for the age predilection of equine proliferative enteropathy (EPE). Additional objectives included examination of various risk factors for the development of EPE as well as the determination of naturally occurring attack rates for clinical and subclinical EPE. Methods: Prospective, multifarm field study. Methods: A total of 369 mare and f...
Detection of Equid herpesvirus type 2 and 5 DNA in uterine flushings of mares with reproductive disorders.
Veterinary microbiology    October 13, 2014   Volume 174, Issue 3-4 570-576 doi: 10.1016/j.vetmic.2014.09.025
Marenzoni ML, Sforna M, Stefanetti V, Casagrande Proietti P, Brignone L, Del Sero A, Falcioni F, Orvieto S, Tamantini C, Tiburzi A, Valentini S....In recent years, there has been increasing evidence of the potential pathogenic significance of equine gammaherpesviruses in the horse. In humans, cattle and mice, gammaherpesviruses have already been associated with uterine infection. The aim of the present study was to investigate the presence of gammaherpesviruses in uterine flushings of mares with reproductive problems and to evaluate if there was a possible statistical association with clinical and laboratory findings in these cases. A total of 80 uterine flushings were collected from 61 mares with different reproductive problems and thes...
Progress on low susceptibility mechanisms of transmissible spongiform encephalopathies.
Dong wu xue yan jiu = Zoological research    October 10, 2014   Volume 35, Issue 5 436-445 doi: 10.13918/j.issn.2095-8137.2014.5.436
Qing LL, Zhao H, Liu LL.Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of fatal neurodegenerative diseases detected in a wide range of mammalian species. The "protein-only" hypothesis of TSE suggests that prions are transmissible particles devoid of nucleic acid and the primary pathogenic event is thought to be the conversion of cellular prion protein (PrP(C)) into the disease-associated isoform (PrP(Sc)). According to susceptibility to TSEs, animals can be classified into susceptible species and low susceptibility species. In this review we focus on several species with l...
Piroplasmosis in an endemic area: analysis of the risk factors and their implications in the control of Theileriosis and Babesiosis in horses.
Parasitology research    October 4, 2014   Volume 114, Issue 1 71-83 doi: 10.1007/s00436-014-4161-9
Guidi E, Pradier S, Lebert I, Leblond A.Theileria equi (Laveran 1901) and Babesia caballi (Nuttall and Strickland 1910) are the causative agents of Equine Piroplasmosis (EP), a severe and problematic disease compromising international movement of horses. Infected horses usually become asymptomatic carriers and, for this reason, their movement across borders may become restricted. The aim of this study was to assess the seroprevalence of EP in Southern France and to evaluate risk factors associated with these parasites. In 2002, we performed a complement fixation test (CF) with blood samples from 443 horses stabled at 95 different fa...
[Horse importation from developing countries and the risk of importing zoonoses].
Tijdschrift voor diergeneeskunde    October 3, 2014   Volume 139, Issue 9 28-34 
Tafro N, Spierenburg MA, Valkenburgh SM.No abstract available
Seroprevalence and risk factors associated with Babesia caballi and Theileria equi infections in donkeys from Southern Italy.
Veterinary journal (London, England : 1997)    September 30, 2014   Volume 202, Issue 3 578-582 doi: 10.1016/j.tvjl.2014.09.025
Piantedosi D, D'Alessio N, Di Loria A, Di Prisco F, Mariani U, Neola B, Santoro M, Montagnaro S, Capelli G, Veneziano V.Equine piroplasmosis (EP) has been frequently described in donkeys in subtropical and tropical regions, but published data reflecting large scale surveys are very limited in Europe. The seroprevalence of Babesia caballi and Theileria equi was determined in a donkey population from Campania Region in Southern Italy using a commercial indirect fluorescent antibody test (IFAT), and the risk factors associated with the occurrence of the infection were assessed. Of 203 samples, the overall seroprevalence for EP was 57.1% (116/203), with 35.5% (72/203) for B. caballi and 44.3% (90/203) for T. equi. ...
Prevalence of supporting limb laminitis in a UK equine practice and referral hospital setting between 2005 and 2013: implications for future epidemiological studies.
The Veterinary record    September 26, 2014   Volume 176, Issue 3 72 doi: 10.1136/vr.102426
Wylie CE, Newton JR, Bathe AP, Payne RJ.The electronic patient records of all equine patients of Rossdales Equine Practice between January 1, 2005 and November 1, 2013 were reviewed to determine the number of cases of supporting limb laminitis (SLL) in a large equine practice and referral hospital setting in the UK and to discuss the implications for future epidemiological studies. The clinical notes were searched electronically for a combination of 'laminitis AND (contralateral OR supporting OR overload OR weight bearing)'. The prevalence of SLL within each identified denominator population and the corresponding 95% CI were calcu...
Survey reveals high risk of injury to equine vets.
The Veterinary record    September 23, 2014   Volume 175, Issue 11 263 doi: 10.1136/vr.g5714
No abstract available
Occurrence of Incisional Complications After Closure of Equine Celiotomies With USP 7 Polydioxanone.
Veterinary surgery : VS    September 17, 2014   Volume 44, Issue 4 521-526 doi: 10.1111/j.1532-950X.2014.12275.x
Anderson SL, Devick I, Bracamonte JL, Hendrick S, Barber SM, Carmalt JL, Wilson DG.To report the occurrence of, and risk factors associated with, incisional complications of equine ventral median celiotomies closed with USP 7 polydioxanone (7PD). Methods: Retrospective case series. Methods: Horses (n = 73; 75 celiotomies). Methods: Medical records (2000-2010) were retrieved and reviewed for horses that had a ventral celiotomy closed with 7PD and survived ≥14 days. Follow-up (>1 year) was obtained from the medical record, owner, or referring veterinarian. Independent variables were selected based on risk factors identified in previous studies, perceived clinical relevan...
A decision tree model for the implementation of a safety strategy in the horse-racing industry.
Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention    September 12, 2014   Volume 21, Issue 2 109-114 doi: 10.1136/injuryprev-2014-041223
Hitchens PL, Curry B, Blizzard CL, Palmer AJ.The profession of a horse-racing jockey is a dangerous one. We developed a decision tree model quantifying the effects of implementing different safety strategies on jockey fall and injury rates and their associated costs. Methods: Data on race-day falls were obtained from stewards' reports from August 2002 to July 2009. Insurance claim data were provided by Principal Racing Authorities and workers' compensation authorities in each jurisdiction. Fall and claim incidence data were used as baseline rates. The model considered (1) the status quo, in which policy was unchanged; and (2) compared it...
Hendra virus in Queensland, Australia, during the winter of 2011: veterinarians on the path to better management strategies.
Preventive veterinary medicine    August 19, 2014   Volume 117, Issue 1 40-51 doi: 10.1016/j.prevetmed.2014.08.002
Mendez D, Buttner P, Speare R.Following the emergence of Hendra virus (HeV), private veterinarians have had to adopt additional infection control strategies to manage this zoonosis. Between 1994 and 2010, seven people became infected with HeV, four fatally. All infected people were at a higher risk of exposure from contact with horses as they were either veterinary personnel, assisting veterinarians, or working in the horse industry. The management of emerging zoonoses is best approached from a One Health perspective as it benefits biosecurity as well as a public health, including the health of those most at risk, in this ...
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