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Topic:Soft Tissue

Soft tissue in horses encompasses the non-bony structures that support and connect various parts of the body, including muscles, tendons, ligaments, and fascia. These tissues are essential for movement, stability, and overall musculoskeletal function. Injuries to soft tissue can result from trauma, overuse, or improper biomechanics, leading to conditions such as strains, sprains, and tears. Understanding the anatomy, healing processes, and rehabilitation strategies for soft tissue is important for managing equine health and performance. This page compiles peer-reviewed research studies and scholarly articles that explore the structure, function, and treatment of soft tissue injuries in horses.
What is your diagnosis? Minimal soft-tissue swelling of the tarsocrural and proximal intertarsal joints and a minimally displaced oblique slab fracture of the third tarsal bone.
Journal of the American Veterinary Medical Association    April 25, 2001   Volume 218, Issue 7 1085-1086 doi: 10.2460/javma.2001.218.1085
Bolt DM, Hubert JD, Williams J.No abstract available
Pythiosis with bone lesions in a pregnant mare.
Journal of the American Veterinary Medical Association    June 9, 2000   Volume 216, Issue 11 1795-1760 doi: 10.2460/javma.2000.216.1795
Worster AA, Lillich JD, Cox JH, Rush BR.A 9-year-old pregnant mare was referred for evaluation of a nonhealing wound of 8 weeks' duration on the lateral aspect of the left forelimb. A soft tissue mass encircled the proximal two thirds of the metacarpus; radiography revealed a moderate periosteal reaction affecting metacarpal bone i.v. Histologic and immunohistochemical examinations revealed eosinophilic granulomatous inflammation and Pythium sp in the soft tissues. The mare was treated for 12 days with antimicrobials, medicated wound dressings, debridement, and i.v. administration of sodium iodide; radiography revealed progression o...
Use of radiography, computed tomography and magnetic resonance imaging for evaluation of navicular syndrome in the horse. Widmer WR, Buckwalter KA, Fessler JF, Hill MA, VanSickle DC, Ivancevich S.Radiographic evaluation of navicular syndrome is problematic because of its inconsistent correlation with clinical signs. Scintigraphy often yields false positive and false negative results and diagnostic ultrasound is of limited value. Therefore, we assessed the use of computed tomography and magnetic resonance imaging in a horse with clinical and radiographic signs of navicular syndrome. Cadaver specimens were examined with spiral computed tomographic and high-field magnetic resonance scanners and images were correlated with pathologic findings. Radiographic changes consisted of bony remodel...
Cimetidine inhibits nitric oxide associated nitrate production in a soft-tissue inflammation model in the horse.
Journal of veterinary pharmacology and therapeutics    June 18, 1999   Volume 22, Issue 2 136-147 doi: 10.1046/j.1365-2885.1999.00196.x
Hunter RP, Short CR, McClure JR, Koch CE, Keowen ML, VanSteenhouse JL, Dees AA.Cimetidine (CIM) is an H2-receptor antagonist that has been used in racehorses in an attempt to reduce the occurrence of stress-related gastric ulceration. It has also been shown to produce several useful effects other than its gastric acid suppression properties. Further, it is a well documented antagonist of cytochrome P-450 (CYP) mediated oxygenation reactions. Nitric oxide (NO), a recently discovered mediator or modifier of numerous physiological functions, is generated by several forms of nitric oxide synthase (NOS), one of which is inducible (iNOS). Inducible NOS, expressed in neutrophil...
Pathologic changes in the lumbosacral vertebrae and pelvis in Thoroughbred racehorses.
American journal of veterinary research    February 27, 1999   Volume 60, Issue 2 143-153 
Haussler KK, Stover SM, Willits NH.To describe the prevalence, characteristics, and severity of soft-tissue and osseous lesions in the caudal portion of the thoracic and lumbosacral vertebral column and pelvis in Thoroughbred racehorses. Methods: 36 Thoroughbred racehorses that died or were euthanatized at California racetracks between October 1993 and July 1994. Methods: Lumbosacral and pelvic specimens were collected and visually examined for soft-tissue and osseous lesions. Results: Acute sacroiliac joint injury was observed in 2 specimens. Signs of chronic laxity or subluxation of the sacroiliac joint were not observed in a...
Imaging basilar skull fractures in the horse: a review. Ramirez O, Jorgensen JS, Thrall DE.Due to the complex nature of the anatomy of the equine head, superimposition of numerous structures, and poor soft tissue differentiation, radiography may be of limited value in the diagnosis of basilar skull fractures. However, in many horses radiographic changes such as soft tissue opacification of the guttural pouch region, irregular bone margination at the sphenooccipital line, attenuation of the nasopharynx, ventral displacement of the dorsal pharyngeal wall and the presence of irregularly shaped bone fragments in the region of the guttural pouches are suggestive of a fracture of the skul...
Dental imaging.
The Veterinary clinics of North America. Equine practice    September 22, 1998   Volume 14, Issue 2 259-271 doi: 10.1016/s0749-0739(17)30197-9
O'Brien RT, Biller DS.Radiography continues to be the initial test of choice in equine dental imaging for reasons of availability and ability to detect bone and tooth changes. Contrast radiography may be useful to characterize dental involvement in cases with draining tracts. For radiographically occult lesions, other modalities are useful. CT is better than plain radiography due to the inherent avoidance of superimposition of the opposite dental arcade, excellent bone density characterization, and good spatial resolution. Nuclear medicine may be useful to verify bone involvement in the dental region in cases in wh...
Traumatic dental disease and soft tissue injuries of the oral cavity.
The Veterinary clinics of North America. Equine practice    September 22, 1998   Volume 14, Issue 2 333-347 doi: 10.1016/s0749-0739(17)30201-8
Hague BA, Honnas CM.Trauma to the oral cavity can result in an array of injuries affecting teeth, bone, and soft tissue. A thorough examination of the oral cavity is often facilitated by employing a full-mouth speculum after the horse has been tranquilized. Identification of broken, loose, or split teeth; fractures of the premaxilla or mandible; and avulsion or laceration of soft tissue structures such as the lips or tongue is usually straightforward. Treatment options vary depending on the structure involved; however, appropriate treatment generally results in a functional and cosmetically acceptable end result....
Effect of copper supplementation on the copper status of pasture-fed young Thoroughbreds.
Equine veterinary journal    June 11, 1998   Volume 30, Issue 3 204-210 doi: 10.1111/j.2042-3306.1998.tb04489.x
Pearce SG, Grace ND, Firth EC, Wichtel JJ, Holle SA, Fennessy PF.The effect of copper supplementation of pasture fed mares and foals on the copper status of the foals, in terms of plasma, soft tissue and bone copper concentrations and caeruloplasmin activity, was investigated. Twenty-one Thoroughbred foals from either control mares (n = 9), or copper-supplemented mares (n = 12) were divided randomly into control (pasture only, n = 10) or supplemented (pasture and oral copper sulphate, n = 11) groups. The pasture diet was grazed by all animals, and contained 4.4-8.6 mg Cu/kg dry matter (DM). The copper supplement for the mares contained copper sulphate equiv...
Effects of inflammation-associated acute-phase response on hepatic and renal indices in the horse.
Australian veterinary journal    May 14, 1998   Volume 76, Issue 3 187-194 doi: 10.1111/j.1751-0813.1998.tb10126.x
Mills PC, Auer DE, Kramer H, Barry D, Ng JC.To determine the effect of an acute soft tissue inflammatory response on biochemical and haematological indices of hepatic and renal function in the Thoroughbred horse. Methods: Soft tissue inflammation was induced in four Thoroughbred horses by intramuscular injections of Freund's complete adjuvant. The horses were clinically examined and blood and urine samples were collected before and after the adjuvant injections. Biochemical and haematological indices were measured in samples collected and used to determine the onset of the acute-phase response and to assess hepatic and renal function at...
Effect of bilateral blockade of the pharyngeal branch of the vagus nerve on soft palate function in horses.
American journal of veterinary research    May 1, 1998   Volume 59, Issue 4 504-508 
Holcombe SJ, Derksen FJ, Stick JA, Robinson NE.To determine the effect of bilateral blockade of the pharyngeal branch of the vagus nerve on soft palate function in horses. Methods: 5 Standardbreds. Methods: Peak tracheal inspiratory and expiratory pressures and airflow were measured while horses exercised at the speeds corresponding to 75 and 100% of the speed that resulted in maximal heart rate, with and without pharyngeal branch of the vagus nerve blockade. Respiratory frequency-to-stride frequency coupling ratio was measured by correlating foot fall measurements with respiratory frequency. The pharyngeal branch of the vagus nerve was bl...
What is your diagnosis? Soft tissue injury draining into the bicipital bursa.
Journal of the American Veterinary Medical Association    February 21, 1998   Volume 212, Issue 3 349-350 
Mirza MH, Martin GS, Williams J.No abstract available
Gross and ultrasonographic anatomy of the carpal flexor tendon sheath in horses.
The Veterinary record    December 24, 1997   Volume 141, Issue 19 489-495 doi: 10.1136/vr.141.19.489
Cauvin ER, Munroe GA, Boswell J, Boyd JS.This study was undertaken to establish the gross anatomy and the ultrasonographic appearance of the carpal digital flexor tendon sheath (carpal sheath) and the palmar carpal region in normal horses. The isolated forelimbs from 15 horses were used to study the morphology of the sheath and associated structures, including a detailed study of the location of the main blood vessels and nerves in that region. These limbs and the forelimbs of five live, sound horses were also examined ultrasonographically. The examination yielded good soft tissue detail of the tendons and ligaments, synovial and per...
The soft-tissue components of the vomeronasal organ in pigs, cows and horses.
Anatomia, histologia, embryologia    October 23, 1997   Volume 26, Issue 3 179-186 doi: 10.1111/j.1439-0264.1997.tb00122.x
Salazar I, Quinteiro PS, Cifuentes JM.The soft-tissue components of the vomeronasal organ of the pig, the cow and the horse were studied with the aid of dissection, microdissection, and light microscopy and immunohistochemistry of series of transverse sections. In horses, the rostral end of the incisive duct was blind: thus, unlike in pigs and cows, there was no communication between the vomeronasal organ and the oral cavity. In all three species, the central part of the vomeronasal duct bore the 'typical' respiratory/ receptor epithelium lining on its lateral and medical walls. The rostral part of the duct was characterized by st...
Intramuscular bioavailability of ketoprofen lysine salt in horses.
The veterinary quarterly    June 1, 1997   Volume 19, Issue 2 65-68 doi: 10.1080/01652176.1997.9694743
Anfossi P, Villa R, Montesissa C, Carli S.Lysine salts are often used in human pharmaceuticals to increase the solubility and absorption of acidic drugs when these are administered parenterally. In this study the intramuscular bioavailability of ketoprofen administered as the lysine salt was evaluated in horses (n = 5) treated intravenously and intramuscularly (2.2 mg/kg active substance) in a cross-over study. The absorption rate of ketoprofen administered as the lysine salt was rather low: the mean residence time increased from 31.7 min after IV injection to 128.9 min (after IM injection), and the bioavailability was high (mean 92.4...
Magnetic resonance imaging of the equine metacarpophalangeal joint: three-dimensional reconstruction and anatomic analysis. Martinelli MJ, Kuriashkin IV, Carragher BO, Clarkson RB, Baker GJ.Magnetic resonance imaging was used to examine the equine metacarpophalangeal joint. Thirty-two saggital images generated by partial volume imaging were transferred to a computer for three-dimensional reconstruction and analysis. All the tissues constituting the metacarpophalangeal joint were readily identified. The most significant increase finding regarded the soft tissues on the palmar aspect of the metacarpophalangeal joint and their interactions with the proximal sesamoid bones. The equine metacarpophalangeal joint has not previously been evaluated using 3-dimensional imaging software.
Clinical efficacy of ampicillin, pivampicillin and procaine penicillin G in a soft tissue infection model in ponies.
Journal of veterinary pharmacology and therapeutics    December 1, 1996   Volume 19, Issue 6 445-453 doi: 10.1111/j.1365-2885.1996.tb00081.x
Ensink JM, Klein WR, Barneveld A, Vulto AG, Van Miert AS.Tissue chambers, implanted subcutaneously in ponies, were inoculated with Streptococcus zooepidemicus. The animals received either no antibiotics or one of the following treatments: pivampicillin per os (19.9 mg/kg, equivalent to 15 mg/kg ampicillin, every 12 h) for 7 or 21 days (7 and 5 ponies, respectively), procaine penicillin G intramuscularly (12 mg/kg = 12,000 IU/kg, every 24 h) for 7 days (7 ponies), or ampicillin sodium intravenously (equivalent to 15 mg/ kg ampicillin, every 8 h) for 1 day (5 ponies). Only intravenous administration was started before infection (prophylactically), the...
The effect of inflammation on the disposition of phenylbutazone in thoroughbred horses.
Journal of veterinary pharmacology and therapeutics    December 1, 1996   Volume 19, Issue 6 475-481 doi: 10.1111/j.1365-2885.1996.tb00085.x
Mills PC, Ng JC, Auer DE.The effect of inflammation on the disposition of phenylbutazone (PBZ) was investigated in Thoroughbred horses. An initial study (n = 5) in which PBZ (8.8 mg/kg) was injected intravenously twice, 5 weeks apart, suggested that the administration of PBZ would not affect the plasma kinetics of a subsequent dose. Two other groups of horses were given PBZ at either 8.8 mg/kg (n = 5) or 4.4 mg/kg (n = 4). Soft tissue inflammation was then induced by the injection of Freud's adjuvant and the administration of PBZ was repeated at a dose level equivalent to, but five weeks later than, the initial dose. ...
Correlation between anatomic features and low-field magnetic resonance imaging of the equine metacarpophalangeal joint.
American journal of veterinary research    October 1, 1996   Volume 57, Issue 10 1421-1426 
Martinelli MJ, Baker GJ, Clarkson RB, Eurell JC, Pijanowski GJ, Kuriashkin IV, Carragher BO.To expand our current knowledge and to establish limits of correlation between signal intensities of the magnetic resonance (MR) image and actual macroscopic and microscopic anatomic features of the imaged structures of the equine metacarpophalangeal joint (MCPJ). Methods: The right MCPJ was obtained from 4 adult horses that were euthanatized for reasons unrelated to the musculoskeletal system. Methods: The distal portion of the right forelimbs was collected from 4 equine cadavers. The bones were drilled to provide fixed reference points and examined by MR imaging. After imaging, the joints we...
Ultrasonographic examination of the femorotibial articulation in horses: imaging of the cranial and caudal aspects.
Equine veterinary journal    July 1, 1996   Volume 28, Issue 4 285-296 doi: 10.1111/j.2042-3306.1996.tb03092.x
Cauvin ER, Munroe GA, Boyd JS, Paterson C.The aim of this study was to determine the normal ultrasonographic features of the cranial and caudal aspects of the femorotibial articulation and, in particular, to establish a method of examining the menisci, cruciate and meniscal ligaments ultrasonographically. Twenty hindlimbs isolated post mortem from 10 horses were used to study the normal ultrasonographic and gross anatomy of the femorotibial joint. Five stifles from 3 normal, live horses were also examined with B-mode, real-time ultrasound imaging. The results of the anatomical study are presented. The joint surfaces, menisci, cruciate...
Differences in quantitated electroencephalographic variables during surgical stimulation of horses anesthetized with isoflurane.
Veterinary surgery : VS    May 1, 1996   Volume 25, Issue 3 249-255 doi: 10.1111/j.1532-950x.1996.tb01409.x
Otto KA, Voight S, Piepenbrock S, Deegen E, Short CE.The effects of noxious surgical stimulation on the electroencephalogram (EEG) in 15 horses anesthetized with isoflurane were evaluated during orthopedic (group 1) and soft tissue (group 2) procedures. The quantitative EEG variables theta/delta ratio (T/D), alpha/delta ratio (A/D), beta/delta ratio (B/D), median power frequency (MED), and 80% spectral edge frequency (SEF 80) recorded during Surgeries at 1.7% end-tidal concentration of isoflurane (ET(iso)) were compared with values from five nonstimulated control horses anesthetized at 1,7% ET(iso). The EEG variables T/D, A/D, MED, and SEF 80 fr...
Characterization of a sterile soft-tissue inflammation model in thoroughbred horses.
Journal of veterinary pharmacology and therapeutics    February 1, 1996   Volume 19, Issue 1 44-49 doi: 10.1111/j.1365-2885.1996.tb00007.x
Guthrie AJ, Short CR, Swan GE, Mülders MS, Killeen VM, Nurton JP.This paper describes the use of subcutaneously-placed tissue chambers as a sterile soft-tissue inflammation model in Thoroughbred horses. Acute, non-immune inflammation was initiated by injecting a sterile lambda carrageenan solution into a tissue chamber. This model was used to study the temporal changes in oxygen and carbon dioxide tensions, pH, bicarbonate, protein, albumin, prostaglandin E2 (PGE2) and leukotriene B4 (LTB4) concentrations, cell counts and differential counts in tissue fluid from inflamed tissue chambers and control chambers. Skin temperatures over control and inflamed chamb...
Ultrasonographic anatomy of the dorsal and abaxial aspects of the equine fetlock.
Equine veterinary journal    January 1, 1996   Volume 28, Issue 1 54-62 doi: 10.1111/j.2042-3306.1996.tb01590.x
Denoix JM, Jacot S, Bousseau B, Perrot P.This paper describes normal ultrasound images of the soft tissues of the dorsal and abaxial aspects of the equine fetlock. The palmar aspect of the fetlock is not discussed because it is related to the suspensory apparatus and flexor tendon anatomy which has been previously described. Ultrasound scanning was performed with 7.5 MHz linear or 10 MHz sector probes and recorded on 7.5 cm U-matic videocassettes allowing further retrospective data analysis, computer manipulation and good image reproducibility. Sagittal, parasagittal, frontal and transverse ultrasound scans of 13 lameness free mature...
Intra-articular pressure, elastance, and range of motion in flexion of the equine metacarpophalangeal joint.
American journal of veterinary research    October 1, 1995   Volume 56, Issue 10 1362-1371 
Strand E, Martin GS, Crawford MP, Kamerling SG, Burba DJ, Kearney MT.A study was done to determine whether intra-articular pressure is increased in equine metacarpophalangeal joints with increasing degrees of synovial distention, and to correlate elastance of the soft tissue forming the dorsal pouch of the metacarpophalangeal joint to maximal range of motion in flexion. Sixty seven metacarpophalangeal joints in 36 horses were categorized by palpation and visual inspection of the palmar pouch into 1 of 4 increasing grades of distention. Intra-articular pressures were then measured, using 2 pressure transducers attached to 22 gauge needles, from the dorsal and pa...
Soft tissue injuries of the tarsus.
The Veterinary clinics of North America. Equine practice    August 1, 1995   Volume 11, Issue 2 235-247 doi: 10.1016/s0749-0739(17)30321-8
Dik KJ, Leitch M.Contrast radiography provides a clear survey of the size, shape, and location of extratendovaginal fluid-filled cavities, distended bursa, and tendon sheaths and demonstrates intersynovial communication. Ultrasonography effectively demonstrates Achilles tendon injury, slippage of the SDFT off the summit of the calcaneus, assorted ligamentous injuries, and cystic or solid extratendovaginal masses. It will also demonstrate distended bursae and tendon sheaths, but it is not as effective in demonstrating a synovial herniation, or a narrow synovial fistula. Contrast radiography may prove to be the ...
Miscellaneous conditions of tendons, tendon sheaths, and ligaments.
The Veterinary clinics of North America. Equine practice    August 1, 1995   Volume 11, Issue 2 315-337 doi: 10.1016/s0749-0739(17)30324-3
Dyson SJ, Dik KJ.The use of diagnostic ultrasonography has greatly enhances our ability to diagnose injuries of tendons and tendon sheaths that were previously either unrecognized or poorly understood. For may of these injuries, there is currently only a small amount of follow-up data. This article considers injuries of the deep digital flexor tendon and its accessory ligament, the carpal tunnel syndrome soft tissue swellings on the dorsal aspect of the carpus, intertubercular (bicipital) bursitis and bicipital tendinitis, injuries of the gastrocnemius tendon, common calcaneal tendinitis, rupture of peroneus (...
Blood gas values during intermittent positive pressure ventilation and spontaneous ventilation in 160 anesthetized horses positioned in lateral or dorsal recumbency.
Veterinary surgery : VS    May 1, 1995   Volume 24, Issue 3 266-276 doi: 10.1111/j.1532-950x.1995.tb01330.x
Day TK, Gaynor JS, Muir WW, Bednarski RM, Mason DE.One hundred sixty horses were anesthetized with xylazine, guaifenesin, thiamylal, and halothane for elective soft tissue and orthopedic procedures. Horses were randomly assigned to one of four groups. Group 1 (n = 40): Horses positioned in lateral (LRG1; n = 20) or dorsal (DRG1; n = 20) recumbency breathed spontaneously throughout anesthesia. Group 2 (n = 40): Intermittent positive pressure ventilation (IPPV) was instituted throughout anesthesia in horses positioned in lateral (LRG2; n = 20) or dorsal (DRG2; n = 20) recumbency. Group 3 (n = 40): Horses positioned in lateral (LRG3; n = 20) or d...
Soft tissue emergency in adult horses.
The Veterinary clinics of North America. Equine practice    December 1, 1994   Volume 10, Issue 3 575-590 doi: 10.1016/s0749-0739(17)30348-6
French DA.Equine practitioners are frequently called to attend to soft tissue injuries. The majority of these cases are routine and straightforward; however, a certain percentage may present as a life-threatening situation with potentially serious complications. Client communication, adequate preparation, patient stabilization, accurate injury assessment and appropriate wound preparation are key factors to expedite recovery and achieve a favorable outcome. Understanding the limitations of field therapy and deciding when to transport the case to a clinic or referral center plays an important role in the ...
Surgical repair of iatrogenic soft palate defects in two horses.
Journal of the American Veterinary Medical Association    November 1, 1994   Volume 205, Issue 9 1315-1317 
Holcombe SJ, Robertson JT, Richardson L.A 4-year-old Thoroughbred filly was referred for evaluation of a soft palate defect that had been created several weeks earlier during surgical correction of epiglottic entrapment, performed transorally. Surgical correction of the defect was performed via mandibular symphysiotomy. At 85 days after repair, the horse raced successfully. A 2-year-old Thoroughbred filly was admitted for evaluation and treatment of epiglottic entrapment. The soft palate was lacerated during transnasal division of the entrapping membrane. A 2-cm full-thickness soft palate laceration was repaired transorally.
A study of the biomechanical properties of the adult equine linea alba: relationship of tissue bite size and suture material to breaking strength.
Veterinary surgery : VS    November 1, 1994   Volume 23, Issue 6 435-441 doi: 10.1111/j.1532-950x.1994.tb00504.x
Trostle SS, Wilson DG, Stone WC, Markel MD.The purposes of this study were to mechanically determine the optimal tissue bite size and to evaluate seven suture materials at their largest commercially available size for breaking strength and stiffness using cadaveric adult equine linea alba. Soft tissues were removed from the abdominal fascia of 16 adult horses. Individual test sections were created from the entire linea alba and labeled (1 through 6) starting at the umbilicus and extending craniad. A single biomechanical test was performed on each test section. Tissue bite size (3, 6, 9, 12, 15, 18, and 21 mm) significantly altered brea...