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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Clinical application of interferons in large animal medicine.
Journal of the American Veterinary Medical Association    May 15, 1996   Volume 208, Issue 10 1711-1715 
Moore BR.Interferons are efficacious therapeutic agents for treatment of several clinically important diseases in cattle and horses. In some instances, the therapeutic goal of IFN administration is prevention or clinical cure of acute viral infections. On the other hand, IFN may serve as adjunctive treatment to diminish clinical manifestations of disease and improve the quality of life. Oral administration of IFN alpha appears to be a safe and convenient route of administration, and the therapeutic benefit likely develops via unique mechanisms involving oropharyngeal-associated lymphoid tissue for diss...
Penetrating keratoplasty for treatment of recurrent squamous cell carcinoma of the cornea in a horse.
Journal of the American Veterinary Medical Association    May 15, 1996   Volume 208, Issue 10 1692-1694 
van der Woerdt A, Gilger BC, Wilkie DA.Squamous cell carcinoma involving the cornea and conjunctiva of the left eye in a 14-year-old horse was treated by superficial keratectomy in combination with beta-radiation and radiofrequency hyperthermia. The tumor recurred 4 months later in the central cornea at the edge of the previous keratectomy site. Penetrating keratoplasty was performed in an effort to remove the tumor and retain a visual eye. The eye was visual 13 months after surgery. Mild fibrosis and vascularization were observed in the area of the penetrating keratoplasty.
What is your diagnosis? Supraspinous bursitis (fistulous withers).
Journal of the American Veterinary Medical Association    May 15, 1996   Volume 208, Issue 10 1649-1650 
Cole DJ, Chaffin MK.No abstract available
[Spring symposium Group Horse Medicine on 6 March 1996 in Amersfoort. Top sport without doping is (not) possible!].
Tijdschrift voor diergeneeskunde    May 15, 1996   Volume 121, Issue 10 295-299 
No abstract available
Blue-cone horizontal cells in the retinae of horses and other equidae.
The Journal of neuroscience : the official journal of the Society for Neuroscience    May 15, 1996   Volume 16, Issue 10 3381-3396 doi: 10.1523/JNEUROSCI.16-10-03381.1996
Sandmann D, Boycott BB, Peichl L.The morphology of horizontal cells chiefly of the horse, but also of asses, mules, and a zebra, has been examined by Lucifer yellow injections into lightly fixed retinae and by immunocytochemistry. In common with other mammals, equids have a B-type horizontal cell, i.e., a cell with dendrites synapsing with cones and possessing a single axon synapsing with rods. Most mammalian retinae have a further type of horizontal cell, the A-type, also synapsing with cones but without an axon. The second type of horizontal cell in equids also has no axon; otherwise, it is most unusual. Compared with other...
Effect of aluminum hydroxide/magnesium hydroxide antacid and bismuth subsalicylate on gastric pH in horses.
Journal of the American Veterinary Medical Association    May 15, 1996   Volume 208, Issue 10 1687-1691 
Clark CK, Merritt AM, Burrow JA, Steible CK.To assess the effect of aluminum hydroxide/magnesium hydroxide antacid and bismuth subsalicylate on gastric pH in clinically normal horses and to develop guidelines on the use of these agents for treatment of peptic ulcer disease in horses. Methods: Prospective, randomized, controlled trial. Methods: 5 clinically normal adult horses with chronically implanted gastric cannulas. Methods: Each horse received all 5 treatments (30 g of aluminum hydroxide/15 g of magnesium hydroxide, 12 g of aluminum hydroxide/6 g of magnesium hydroxide, 10.5 g of bismuth subsalicylate, 26.25 g of bismuth subsalicyl...
Treatment of intrasynovial infection with gentamicin-impregnated polymethylmethacrylate beads.
The Veterinary record    May 11, 1996   Volume 138, Issue 19 460-464 doi: 10.1136/vr.138.19.460
Butson RJ, Schramme MC, Garlick MH, Davies JV.Gentamicin-impregnated polymethylmethacrylate beads were used in the treatment of infective synovitis in 12 horses and 10 cattle. They had either proved refractory to standard treatments (lavage, debridement, joint drainage and systemic antibiotics) or had evidence of osteomyelitis adjacent to a synovial cavity. All the animals were severely lame. All the cattle and six of the horses had radiological evidence of osteomyelitis in communication with a synovial cavity. The beads were placed intrasynovially under general anaesthesia and left in place for 14 days. One horse and one calf were euthan...
Pharmacokinetics and tolerance of florfenicol in Equidae.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 209-213 doi: 10.1111/j.2042-3306.1996.tb03774.x
McKellar QA, Varma KJ.Florfenicol was administered to horses and ponies at a dose rate of 22 mg/kg bwt by i.v., i.m. and oral routes. Following i.v. administration it had an elimination half-life of 1.8 ± 0.9 h, a body clearance of 0.4 ± 0.11/h.kg and a volume of distribution at steady-state of 0.7 ± 0.2 1/kg. It was highly bioavailable following i.m. (81%) and oral (83%) administration. Less than 15% of the administered dose was excreted unchanged in the urine during the 30 h following administration. Animals treated with florfenicol had elevated bilirubin concentrations. Florfenicol was well tolerated by anima...
Comparison of herniorrhaphy versus clamping of umbilical hernias in horses: a retrospective study of 93 cases (1982-1994).
The Canadian veterinary journal = La revue veterinaire canadienne    May 1, 1996   Volume 37, Issue 5 295-298 
Riley CB, Cruz AM, Bailey JV, Barber SM, Fretz PB.Many uncomplicated umbilical hernias have been managed successfully in foals by the application of a hernia clamp. Isolated reports of complications following clamp application have led some authors to suggest that it is an unsuitable method of treatment. Little information has been published comparing the complication rates associated with the use of hernia clamps and herniorrhaphy in the treatment of umbilical hernias. The purpose of this retrospective study was to report the characteristics of clinical cases of umbilical hernia and to compare the complication rates following these 2 treatme...
Ever since Daisy: today’s endometrium and tomorrow’s placenta.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 170-172 doi: 10.1111/j.2042-3306.1996.tb03768.x
Flood PF.No abstract available
Ultrasound in medical obstetrics: is it applicable to equine fetal medicine?
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 174-176 doi: 10.1111/j.2042-3306.1996.tb03769.x
Lindsay PC, McGLADDERY AJ.No abstract available
What is your diagnosis? Tarsal bone slab fracture in a horse.
Journal of the American Veterinary Medical Association    May 1, 1996   Volume 208, Issue 9 1385-1386 
Sedrish SA, Moore RM, Partington BP.No abstract available
Penetrating wounds of the thorax in 15 horses.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 220-224 doi: 10.1111/j.2042-3306.1996.tb03776.x
Laverty S, Lavoie JP, Pascoe JR, Ducharme N.Clinical features, treatment and outcome of 15 horses with penetrating thoracic wounds are described. The most common cause of trauma was collision with an object (10 horses). Concurrent clinical findings included subcutaneous emphysema (12 horses), pneumothorax (12 horses), haemothorax (5 horses) and pneumomediastinum (6 horses). Axillary wounds were present in 5 horses. Foreign bodies were identified and removed from 2 horses. Wounds were sutured (6 horses) or packed (7 horses). Air was evacuated from the pleural cavities of 11 horses. Eleven horses (73%) were discharged from the hospital. A...
Clarification on foal with cyanoses and intense murmur.
Journal of the American Veterinary Medical Association    May 1, 1996   Volume 208, Issue 9 1381 
Schott HC, Southwood LL, Tobias AH.No abstract available
Minor constituents of sabulous material in equine urine.
Research in veterinary science    May 1, 1996   Volume 60, Issue 3 238-242 doi: 10.1016/s0034-5288(96)90046-6
Díaz-Espiñeira M, Escolar E, Bellanato J, Rodriguez M.The secondary constituents accompanying calcite and vaterite (crystalline forms of calcium carbonate) in the sabulous deposits from 140 vesical samples and one renal sample of equine urine were studied by infrared spectroscopy (IR), scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX). Apatitic calcium phosphate, present in 12 per cent of the samples, generally appeared in the form of spherulites with smooth and rough surfaces. Calcium sulphate, clearly detected by IR in 12.7 per cent of the samples, did not have a characteristic structure under SEM, although EDX detec...
Immunohistochemical detection of virulence-associated antigens of Rhodococcus equi in pulmonary lesions of foals.
Veterinary pathology    May 1, 1996   Volume 33, Issue 3 341-343 doi: 10.1177/030098589603300312
Madarame H, Takai S, Morisawa N, Fujii M, Hidaka D, Tsubaki S, Hasegawa Y.Rhodococcus equi was isolated from the lungs of six foals with bronchopneumonia. All isolates expressed 15-17-kd antigens by immunoblot analysis and contained a virulence-associated plasmid of 85 or 90 kb. Immunohistochemically, R. equi from all pulmonary lesions showed the expression of 15-17-kd antigens mainly in the phagocytic cells. The specific monoclonal antibody to 15-17-kd antigens of R. equi (MAb 10G5) may be an aid in the diagnosis of R. equi-induced pneumonia.
Control of Babesia equi parasitemia.
Parasitology today (Personal ed.)    May 1, 1996   Volume 12, Issue 5 195-198 doi: 10.1016/0169-4758(96)10007-7
Knowles DP.Infection of horses with the hemoprotozoan Babesia equi has been reported in southern Florida, US Virgin Islands, part of Asia, Russia, India, the Middle East, Europe, Africa, Australia, South America, Central America, Mexico, Philippine Islands and some Caribbean islands. The restrictions placed on the international movement of infected horses has refocused attention on potential methods to control or eliminate infection. Don Knowles here discusses the primary chemotherapeutic compounds that have been used; the current knowledge concerning immune responses that potentially contribute to contr...
Quantitative characterization of lymphocyte populations in bronchoalveolar lavage fluid and peripheral blood of normal adult Arabian horses.
Veterinary immunology and immunopathology    May 1, 1996   Volume 51, Issue 1-2 29-37 doi: 10.1016/0165-2427(95)05510-x
Hines MT, Palmer GH, Byrne KM, Brassfield AL, McGuire TC.Bronchoalveolar lavage fluid (BALF) and peripheral blood were obtained from each of 17 adult Arabian mares and absolute numbers and relative lymphocyte proportions were determined for total T lymphocytes, using CD2 as a marker, CD4 + T lymphocytes, CD8 + T lymphocytes, CD5 + lymphocytes, and sIgM + B lymphocytes. The marked variation in BALF cell recovery resulted in wide variation in absolute values for each lymphocyte subset. The relative proportions of gated BALF lymphocytes were much less variable and provided a basis for comparison of lymphocyte subsets between the BALF and peripheral blo...
Application of a hook plate for management of equine ulnar fractures.
Veterinary surgery : VS    May 1, 1996   Volume 25, Issue 3 207-212 doi: 10.1111/j.1532-950x.1996.tb01400.x
Murray RC, Debowes RM, Gaughan EM, Bramlage LR.Closed fractures of the proximal aspect of the ulna were repaired in 10 horses younger than or equal to 6 months of age by application of a hook plate using a tension band principle. Ulnar fractures were classified as type 1A (2 horses), type 1B (4 horses), type 2 (1 horse), type 3 (1 horse), and type 4 (2 horses); all fractures had displacement of a proximal fragment. Complications were implant deformation (4 horses), screw pullout (1 horse), osseous sequestration (1 horse), ulnar fracture through a hole used to apply a tension device (1 horse), and metacarpophalangeal deformity associated wi...
Novel approaches to the purification and identification of cytochrome P450 enzymes in the equine.
Biochemical Society transactions    May 1, 1996   Volume 24, Issue 2 208S doi: 10.1042/bst024208s
Byard J, Marshall DE, Houghton E, Gower DB.No abstract available
Effect of vaccination of ponies with A4 anti-idiotypic antibody on serum idiotype (1C9) and antilipid A concentration.
American journal of veterinary research    May 1, 1996   Volume 57, Issue 5 655-658 
BonenClark GD, MacKay RJ, Ward RE, Sheerin B.To evaluate the humoral response of horses to vaccination, using a murine monoclonal anti-idiotypic antibody (A4) that shares an epitope with lipid A. Methods: Serum concentrations of antilipid A antibody and 1C9 (epitope on murine monoclonal antilipid A antibody) were measured serially during the period of vaccination with A4. Methods: 6 clinically normal adult ponies. Methods: Ponies were inoculated IM 3 times at monthly intervals with A4. Two weeks after each inoculation, serum was obtained and was assayed by ELISA for antilipid A and 1C9 concentrations. Additional vaccinations were given t...
The ontogeny of serum insulin-like growth factor-I concentration in foals: effects of dam parity, diet, and age at weaning.
Domestic animal endocrinology    May 1, 1996   Volume 13, Issue 3 197-209 doi: 10.1016/0739-7240(96)00014-8
Cymbaluk NF, Laarveld B.The effects of dam parity, age at weaning, and preweaning diet were examined in the ontogeny of serum insulin-like growth factor-I (IGF-I) concentrations in foals. Foals born to 13 primiparous and 19 multiparous draft-cross mares were weighed and bled near birth. About one-half of the foals in each group were weaned early (about 13 wk old); the remaining foals were weaned late (about 16 wk of age). Pooled values for serum IGF-I concentrations between birth and 17 wk of age were higher (P < 0.065) for foals born to multiparous (386 ng/ml) than to primiparous mares (237.5 ng/ml). Colts (378 n...
Mummified fetus in a mare.
Journal of the American Veterinary Medical Association    May 1, 1996   Volume 208, Issue 9 1438-1440 
Barber JA, Troedsson MH.A 12-year-old Arabian mare with a history of repeated early embryonic losses gave birth to a mummified fetus. The fetus was not the result of a pregnancy with twins. The mare had been given a progestogen throughout gestation and expelled the mummified fetus at about 325 days of gestation, 2 weeks after progestogen treatment was discontinued. We estimate that the size of the fetus was consistent with a fetal age of 5 months. The mare and mummified fetus illustrated that progestogen administration after 100 days of gestation can promote retention of a nonviable fetus. When the fetoplacental unit...
Metacarpophalangeal joint synovial pad fibrotic proliferation in 63 horses.
Veterinary surgery : VS    May 1, 1996   Volume 25, Issue 3 199-206 doi: 10.1111/j.1532-950x.1996.tb01399.x
Dabareiner RM, White NA, Sullins KE.Medical records, radiographs, and sonograms of 63 horses with metacarpophalangeal joint synovial pad proliferation were examined retrospectively. All horses had lameness, joint effusion, or both signs associated with one or both metacarpophalangeal joints. Bony remodeling and concavity of the distodorsal aspect of the third metacarpal bone (Mc3) just proximal to the metacarpal condyles was identified by radiography in 71 joints (93%); 24 joints (32%) had radiographic evidence of a chip fracture located at the proximal dorsal aspect of the proximal phalanx. Fifty-four joints (71%) were examined...
Accessory ossification centres associated with osteochondral fragments in the extremities of horses.
Journal of comparative pathology    May 1, 1996   Volume 114, Issue 4 385-398 doi: 10.1016/s0021-9975(96)80014-4
Grøndahl AM, Jansen JH, Teige J.Fifty-six tarsocrural joints and 94 metatarsophalangeal joints were examined, at necropsy, from horses aged < or = 2 years. Osteochondral fragments at the cranial aspect of the intermediate ridge of the distal part of the tibia were seen in six horses, and at the proximoplantar aspect of the proximal phalanx in seven horses. Defects in the proximoplantar aspect of the proximal phalanx without osteochondral fragments were seen in a further two horses. Inflammatory and degenerative changes were not observed in any of the joints examined. From the incidence and natural course of these fragment...
Inhibition of the protease activity in tracheobronchial aspirates of horses with chronic obstructive pulmonary disease.
American journal of veterinary research    May 1, 1996   Volume 57, Issue 5 603-607 
Koivunen AL, Maisi P, Fang W, Sandholm M.To clarify the role of proteolytic enzymes in the pathogenesis of chronic obstructive pulmonary disease (COPD) in horses, and to investigate new possibilities for treatment of this disease by interfering in the proteolytic process. Methods: Effect of antiproteolytic activity of selected protease inhibitors on tracheal aspirates was studied in vitro, and the inhibition profiles were compared with those of purified proteases. Methods: Respiratory tract secretions with antiproteolytic activity from 9 horses with COPD. Methods: Caseinolytic agar-diffusion assay. Results: The protease-inhibition pr...
Pericarditis and pleuritis caused by Mycoplasma felis in a horse.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 237-240 doi: 10.1111/j.2042-3306.1996.tb03779.x
Morley PS, Chirino-Trejo M, Petrie L, Krupka L, Schwab M.No abstract available
Development of subchondral cystic lesions after articular cartilage and subchondral bone damage in young horses.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 225-232 doi: 10.1111/j.2042-3306.1996.tb03777.x
Ray CS, Baxter GM, McILWRAITH CW, Trotter GW, Powers BE, Park RD, Steyn PF.The objective of this study was to determine if damage to the articular cartilage alone or articular cartilage plus subchondral bone of the distal medial femoral condyle of young, exercised horses resulted in the formation of subchondral cystic lesions. Twelve Quarter Horses (age 1-2 years), free of clinical and radiographic signs of osteochondrosis and lameness were used. In 6 horses (Group 1), a 15 times 1 mm linear full thickness defect in the articular cartilage was made arthroscopically on the weightbearing surface of the distal aspect of the medial femoral condyle. In the other 6 horses ...
Chylothorax due to primary thoracic haemangiosarcoma in a horse.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 241-244 doi: 10.1111/j.2042-3306.1996.tb03780.x
Brink P, Wilkins LP, Spano JS.No abstract available
Effects of U-74389G, a novel 21-aminosteroid, on small intestinal ischemia and reperfusion injury in horses.
American journal of veterinary research    May 1, 1996   Volume 57, Issue 5 762-770 
Vatistas NJ, Snyder JR, Hildebrand SV, Harmon FA, Woliner MJ, Barry SJ, Nieto J, Henry P, Enos LR, Magliano D, Brown SA, Drake C.To determine the effects of the 21-aminosteroid, U-74389G, on reperfusion of the equine jejunum, using total (TVO) and partial (PVO) vascular occlusion during the ischemic period. Methods: TVO: 16 healthy horses were randomly allotted to 3 groups-4 horses received the vehicle alone, 6 horses received a low dosage (3 mg/kg o body weight), and 6 horses a high dosage (10 mg/kg) of U-7438G. PVO: 10 healthy horses were randomly allotted to 2 groups--5 horses received the vehicle alone, and 5 horses received the low dosage (3 mg/kg) of U-74389G. Methods: TVO was induced for 1 hour followed by 2 hour...