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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Neutrophil function of neonatal foals is enhanced in vitro by CpG oligodeoxynucleotide stimulation.
Veterinary immunology and immunopathology    November 25, 2011   Volume 145, Issue 1-2 290-297 doi: 10.1016/j.vetimm.2011.11.012
Bordin AI, Liu M, Nerren JR, Buntain SL, Brake CN, Kogut MH, Cohen ND.Rhodococcus equi is an intracellular bacterium that causes pneumonia in foals and immunocompromised adult horses. Evidence exists that foals become infected with R. equi early in life, a period when innate immune responses are critically important for protection against infection. Neutrophils are innate immune cells that play a key role in defense against this bacterium. Enhancing neutrophil function during early life could thus help to protect foals against R. equi infection. The objective of our study was to determine whether in vitro incubation with the TLR9 agonist CpG 2142 would enhance d...
Mating behavior increases workload of the heart in Thoroughbred stallions.
The Journal of veterinary medical science    November 25, 2011   Volume 74, Issue 4 423-428 doi: 10.1292/jvms.11-0360
Hatazoe T, Kubota C, Fujiki M, Misumi K.To evaluate the influence of mating behavior on cardiac function, changes in heart rate (HR), electrocardiogram (ECG), hematocrit (Hct) and serum concentration of alpha-atrial natriuretic peptide (alpha-ANP) were evaluated in 10 clinically sound Thoroughbred stallions before and after mating behavior. The stallions were submitted twice to experimental pseudomating in the same month in 2009 and 2010. Measurements and blood samples were collected at a stable before mating (baseline) and at a covering yard before and after mating. ECG was recorded by a Holter-ECG system. Arrhythmias were detected...
Contagious equine metritis eradicated from Japan.
The Journal of veterinary medical science    November 25, 2011   Volume 74, Issue 4 519-522 doi: 10.1292/jvms.11-0347
Anzai T, Kamada M, Niwa H, Eguchi M, Nishi H.Contagious equine metritis (CEM), a contagious venereal disease of horses, invaded Japan in 1980 and spread in the Thoroughbred population of the Hidaka-Iburi district of Hokkaido. To eradicate CEM, we ran a program aimed at detecting Taylorella equigenitalis, the causal agent, in carrier horses by using the PCR test, followed by culling or treatment. In 2001, the first year of the program, 12,356 Thoroughbred racing stallions and mares were tested and 11 carriers were found. Four, two, one, and one carrier mares were detected in 2002, 2003, 2004, and 2005, respectively, by application of the ...
AAEP releases report on BLM’s wild horses. Report: “Adoption program has evolved into a welfare program”.
Journal of the American Veterinary Medical Association    November 24, 2011   Volume 239, Issue 9 1162-1164 
Larkin M.No abstract available
Pulmonary inflammation due to exercise-induced pulmonary haemorrhage in Thoroughbred colts during race training.
Veterinary journal (London, England : 1997)    November 24, 2011   Volume 190, Issue 2 e3-e6 doi: 10.1016/j.tvjl.2010.08.009
Michelotto PV, Muehlmann LA, Zanatta AL, Bieberbach EWR, Kryczyk M, Fernandes LC, Nishiyama A.This study investigated the putative roles of inflammation and platelet-activating factor (PAF) in exercise-induced pulmonary haemorrhage (EIPH). Two-year-old Thoroughbred colts (n=37) were exercised on a racetrack for 5months before commencement of the study. Each colt was then exercised at 15-16m/s over 800-1000m and broncho-alveolar lavage fluid (BALF) was collected 24h later. The colts were subsequently divided into two groups on the basis of BALF analysis; an EIPH-positive group (presence of haemosiderophages, n=23) and an EIPH-negative group (absence of haemosiderophages, n=14). BALF fro...
Effect of centrifugal fractionation protocols on quality and recovery rate of equine sperm.
Theriogenology    November 23, 2011   Volume 77, Issue 5 959-966 doi: 10.1016/j.theriogenology.2011.10.002
Edmond AJ, Brinsko SP, Love CC, Blanchard TL, Teague SR, Varner DD.Centrifugal fractionation of semen is commonly done to improve quality of human semen in assisted-reproduction laboratories, allowing sperm separation based on their isopycnic points. Sperm with morphologic abnormalities are often more buoyant, promoting their retention above defined density media, with structurally normal sperm passing through the media following centrifugation. Three experiments were conducted to evaluate the effects of density-medium type, centrifuge-tube size, sperm number, and density-medium volume (column height) on stallion sperm quality and recovery rate in sperm pelle...
The mare: a 1000-pound guinea pig for study of the ovulatory follicular wave in women.
Theriogenology    November 23, 2011   Volume 77, Issue 5 818-828 doi: 10.1016/j.theriogenology.2011.09.025
Ginther OJ.The mare is a good comparative model for study of ovarian follicles in women, owing to striking similarities in follicular waves and the mechanism for selection of a dominant follicle. Commonality in follicle dynamics between mares and women include: (1) a ratio of 2.2:1 (mare:woman) in diameter of the largest follicle at wave emergence when the wave-stimulating FSH surge reaches maximum, in diameter increase of the two largest follicles between emergence and the beginning of deviation between the future dominant and subordinate follicles, in diameter of each of the two largest follicles at th...
Thromboelastography in healthy, sick non-septic and septic neonatal foals.
Australian veterinary journal    November 23, 2011   Volume 89, Issue 12 500-505 doi: 10.1111/j.1751-0813.2011.00854.x
Mendez-Angulo JL, Mudge M, Zaldivar-Lopez S, Vilar-Saavedra P, Couto G.To evaluate citrated recalcified thromboelastography (TEG) in healthy newborn foals, and to determine intra-assay, inter-individual and intra-individual (at 12 h, 24 h and 7 days after birth) variations. Additionally, to compare TEG variables, haematological values and conventional coagulation profiles from healthy, sick non-septic, and septic foals. Methods: Prospective study. Methods: The study group comprised 18 healthy, 15 sick non-septic and 17 septic foals. Two citrated (3.2%; 1 : 9 anticoagulant : blood ratio) blood samples were submitted for haemostatic evaluation using a TEG analyser ...
Seroprevalence of Toxoplasma gondii infection among horses in Tunisia.
Parasites & vectors    November 22, 2011   Volume 4 218 doi: 10.1186/1756-3305-4-218
Boughattas S, Bergaoui R, Essid R, Aoun K, Bouratbine A.The present study was conducted to investigate the serological survey of Toxoplasma antibodies in local.horses from three major regions: a neighbourhood of a city in the North (Sidi Thabet), a neighbourhood of a city on the coast (Monastir) and a neighbourhood of a city in the middle (Battan) of Tunisia (North of Africa). Methods: A total of 158 serum samples were obtained from clinically healthy horses which consisted of 111 (32 female, 79 male) 2-10 years old and 47 (11 female, 36 male) older than 10 years. All of the horses were tested for antibodies to T. gondii using the Modified Agglutin...
Clinical neurology.
The Veterinary clinics of North America. Equine practice    November 22, 2011   Volume 27, Issue 3 ix-x doi: 10.1016/j.cveq.2011.08.011
Divers TJ, Johnson AL.No abstract available
Pharmacokinetics and pharmacodynamics of intravenous medetomidine in the horse.
Veterinary anaesthesia and analgesia    November 22, 2011   Volume 39, Issue 1 38-48 doi: 10.1111/j.1467-2995.2011.00669.x
Grimsrud KN, Mama KR, Steffey EP, Stanley SD.To describe the pharmacodynamics and pharmacokinetics following an intravenous (IV) bolus dose of medetomidine in the horse. Methods: Prospective experimental trial. Methods: Eight, mature healthy horses age 11.7 ± 4.6 (mean ± SD) years, weighing 557 ± 54 kg. Methods: Medetomidine (10 μg kg(-1) ) was administered IV. Blood was sampled at fixed time points from before drug administration to 48 hours post administration. Behavioral, physiological and biochemical data were obtained at predetermined time points from 0 minutes to 24 hours post administration. An algometer was also used to measu...
Toxins and adverse drug reactions affecting the equine nervous system.
The Veterinary clinics of North America. Equine practice    November 22, 2011   Volume 27, Issue 3 507-526 doi: 10.1016/j.cveq.2011.08.003
Dawson DR.This article provides an overview of the more common toxins and adverse drug reactions, along with more rare toxins and reactions (Table 1), that result in neurologic dysfunction in horses. A wide variety of symptoms, treatments, and outcomes are seen with toxic neurologic disease in horses. An in-depth history and thorough physical examination are needed to determine if a toxin or adverse drug reaction is responsible for the clinical signs. Once a toxin or adverse drug reaction is identified, the specific antidote, if available, and supportive care should be administered promptly.
Immunohistochemical localisation of progesterone and oestrogen receptors at the placental interface in mares during early pregnancy.
Animal reproduction science    November 22, 2011   Volume 129, Issue 3-4 200-208 doi: 10.1016/j.anireprosci.2011.11.004
Wilsher S, Gower S, Allen WR.Previous reports documenting progesterone receptors (PR) and oestrogen receptors (ER) in the endometrium of early pregnant mares included specimens only up to Day 20 post ovulation. This study aimed to localise PR and ERα on equine feto-maternal tissues between Days 20 and 68 to encompass the period around fixation of the conceptus, development of the endometrial cups and attachment and initial interdigitation of the allantochorion. During early pregnancy mares had the same pattern of PR in the endometrium as that reported for other mammals; namely, a loss of PR from the endometrial epithelia...
Lesions of the equine neck resulting in lameness or poor performance.
The Veterinary clinics of North America. Equine practice    November 22, 2011   Volume 27, Issue 3 417-437 doi: 10.1016/j.cveq.2011.08.005
Dyson SJ.Lesions of the neck are an uncommon primary cause of pain resulting in either lameness or poor performance but should be considered if local analgesic techniques of the limbs fail to abolish lameness or if there are clinical signs directly referable to the neck such as pain, abnormal neck posture, stiffness, or patchy sweating. Accurate diagnosis requires careful clinical examination, exclusion of other causes of lameness or poor performance, and accurate interpretation of diagnostic imaging findings.
Treatment of equine sarcoid in seven Cape mountain zebra (Equus zebra zebra).
Journal of wildlife diseases    November 22, 2011   Volume 47, Issue 4 917-924 doi: 10.7589/0090-3558-47.4.917
Marais HJ, Page PC.Equine sarcoid has been diagnosed in endangered Cape mountain zebra (Equus zebra zebra) in at least two game reserves in South Africa, with prevalence as high as 53% in Bontebok National Park. Seven Cape mountain zebras with sarcoids were treated with either surgical excision, 5-fluorouracil, allogenous vaccine, or a combination of 5-fluorouracil and allogenous vaccine. One of the two sarcoids on one of the 5-fluorouracil-treated zebras was left untreated. The microscopic features of the tumors evaluated showed either all or most of the typical epidermal and dermal histologic features of equin...
Evaluation and management of the recumbent adult horse.
The Veterinary clinics of North America. Equine practice    November 22, 2011   Volume 27, Issue 3 527-543 doi: 10.1016/j.cveq.2011.08.006
Gardner RB.Evaluation and management of recumbent horses are challenging. Familiarity with disorders that can result in recumbency will facilitate more rapid diagnosis and more appropriate formulation of a prognosis. With rapid and appropriate diagnosis, appropriate treatment can be pursued and, with good nursing care, can result in a favorable outcome.
Guttural pouch diseases causing neurologic dysfunction in the horse.
The Veterinary clinics of North America. Equine practice    November 22, 2011   Volume 27, Issue 3 545-572 doi: 10.1016/j.cveq.2011.08.002
Borges AS, Watanabe MJ.The close relationship between guttural pouches, cranial nerves, and sympathetic structures make neurologic abnormalities due to diseases of the guttural pouches (especially mycosis) possible. Recognition of epistaxis or mucopurulent nasal discharge, together with signs of dysfunction of the cranial nerves in contact with the guttural pouches, are important key points in order to consider a comprehensive evaluation of these structures and further definitive diagnosis. Diseases of the guttural pouches can also cause signs such as dysphagia, abnormal soft palate positioning, laryngeal paralysis,...
Purchase examinations and importation requirements for European performance horses and their semen entering the United States.
Compendium (Yardley, PA)    November 22, 2011   Volume 33, Issue 11 E3 
Harland MM, Stewart AJ, Böse R.A comprehensive purchase examination is expected by American clients intent on importing a horse from a foreign country. American veterinarians may be involved in performing purchase examinations in foreign countries or, more often, interpreting findings from foreign veterinarians for their American clients. Exportation and importation requirements for horses and semen vary from country to country. Detailed knowledge of the requirements by all involved veterinarians is essential for efficient and successful international equine travel.
A study of sub-occlusal secondary dentine thickness in overgrown equine cheek teeth.
Veterinary journal (London, England : 1997)    November 22, 2011   Volume 193, Issue 1 53-57 doi: 10.1016/j.tvjl.2011.10.003
Marshall R, Shaw DJ, Dixon PM.The presence of cheek tooth loss or defects, with subsequent overgrowth of the opposing teeth, is common in horses. Little is known about the factors that control the deposition of sub-occlusal secondary dentine (SO2D) in normal equine teeth, but these are likely to include stimulation of the occlusal surface. There appears to be no information on the possible alterations to this process when teeth develop overgrowths and, consequently, of the net effect on SO2D thickness caused by reduced stimulation of the occlusal surface and of absent/reduced normal occlusal wear (attrition). Knowledge of ...
Views sought on equine trading scheme.
The Veterinary record    November 22, 2011   Volume 169, Issue 21 542 doi: 10.1136/vr.d7477
No abstract available
Development of a xylazine constant rate infusion with or without butorphanol for standing sedation of horses.
Veterinary anaesthesia and analgesia    November 22, 2011   Volume 39, Issue 1 1-11 doi: 10.1111/j.1467-2995.2011.00653.x
Ringer SK, Portier KG, Fourel I, Bettschart-Wolfensberger R.To elaborate constant rate infusion (CRI) protocols for xylazine (X) and xylazine/butorphanol (XB) which will result in constant sedation and steady xylazine plasma concentrations. Methods: Blinded randomized experimental study. Methods: Ten adult research horses. Methods: Part I: After normal height of head above ground (HHAG = 100%) was determined, a loading dose of xylazine (1 mg kg(-1) ) with butorphanol (XB: 18 μg kg(-1) ) or saline (X: equal volume) was given slowly intravenously (IV). Immediately afterwards, a CRI of butorphanol (XB: 25 μg kg(-1) hour(-1)) or saline (X) was administer...
Remembering the real war horses.
The Veterinary record    November 22, 2011   Volume 169, Issue 21 543 doi: 10.1136/vr.d7342
No abstract available
Geographic structuring of global EIAV isolates: a single origin for New World strains?
Virus research    November 22, 2011   Volume 163, Issue 2 656-659 doi: 10.1016/j.virusres.2011.11.011
Capomaccio S, Cappelli K, Cook RF, Nardi F, Gifford R, Marenzoni ML, Passamonti F.Equine infectious anaemia virus (EIAV) is classified within the Retroviridae and, like other lentivirus, has the propensity for considerable antigenic variation. An extensive phylogenetic analysis in Bayesian fashion, with significant amounts of new EIAV gag sequence information, revealed a strong geographic compartmentalization clearly related to the phylogeographic history of modern horses, pointing out that New World EIAV strains form a distinct group with a potentially common origin. This evidence suggests that a single founder event may have occurred during the reintroduction of horses to...
Thermally-mediated ultrasound-induced contraction of equine muscular arteries in vitro and an investigation of the associated cellular mechanisms.
Ultrasound in medicine & biology    November 21, 2011   Volume 38, Issue 1 152-161 doi: 10.1016/j.ultrasmedbio.2011.10.017
Martin EM, Duck FA, Winlove CP.We have previously shown that MHz frequency ultrasound causes contraction of the carotid artery in vitro. We now extend this investigation to equine mesenteric arteries and investigate the cellular mechanisms. In vitro exposure of the large lateral cecal mesenteric artery to 4-min periods of 3.2 MHz continuous wave ultrasound at acoustic powers up to 145 mW induced reversible repeatable contraction. The magnitude of the response was linearly dependent on acoustic power and, at 145 mW, the mean increase in wall stress was 0.020 ± 0.017 mN/mm(2) (n = 34). These results are consistent with our p...
Vertical head and trunk movement adaptations of sound horses trotting in a circle on a hard surface.
Veterinary journal (London, England : 1997)    November 21, 2011   Volume 193, Issue 1 73-80 doi: 10.1016/j.tvjl.2011.10.019
Starke SD, Willems E, May SA, Pfau T.Trotting a horse in circles is a standard and important part of the subjective equine lameness examination, yet objective data on this form of locomotion are sparse. The aim of this study was to investigate the effect of trotting in a circle on head and trunk movement symmetry. Vertical movements of the head, withers, os sacrum and left and right tuber coxae were measured using inertial sensors as 12 sound horses were trotted on a hard surface in a straight line and in a circle on both reins. Seven asymmetry measures and hip hike were calculated for each horse for at least nine strides of comp...
First application of axial speed of sound to follow up injured equine tendons.
Ultrasound in medicine & biology    November 21, 2011   Volume 38, Issue 1 162-167 doi: 10.1016/j.ultrasmedbio.2011.10.008
Vergari C, Pourcelot P, Ravary-Plumioën B, Dupays AG, Denoix JM, Mitton D, Laugier P, Crevier-Denoix N.Ultrasonography is an established technique to follow up injured tendons, although the lesions' echogenicity tends to become normal before the tendon is ready to sustain the stresses imposed by exercise. Normalized axial speed of sound (SOS) has been found to correlate with an injured tendon's stiffness; therefore, the purpose of this study was to establish whether SOS would be a useful tool in tendon injury follow-up. Axial SOS was measured in 11 equine superficial digital flexor tendons during a 15-week follow-up period and compared with an ultrasonographic grading system. SOS significantly ...
Standing laparoscopic peritoneal flap hernioplasty technique for preventing recurrence of acquired strangulating inguinal herniation in stallions.
Veterinary surgery : VS    November 21, 2011   Volume 41, Issue 2 292-299 doi: 10.1111/j.1532-950X.2011.00914.x
Wilderjans H, Meulyzer M, Simon O.To describe a standing laparoscopic peritoneal flap hernioplasty (PFH) technique for closure of the vaginal ring, and to evaluate its effect on prevention of recurrent herniation in stallions, previously treated for acquired strangulating inguinal hernia (SIH). Methods: Case series. Methods: Stallions (n = 30) aged 3-15 that had previous acquired SIH. Methods: Bilateral standing laparoscopic PFH was performed on 30 stallions that had previous acquired SIH treated without castration. The vaginal rings were approached from 3 portals, 2 in the paralumbar fossa and a 3rd between the 17th and 18th ...
Risk factors for equine laminitis: a systematic review with quality appraisal of published evidence.
Veterinary journal (London, England : 1997)    November 21, 2011   Volume 193, Issue 1 58-66 doi: 10.1016/j.tvjl.2011.10.020
Wylie CE, Collins SN, Verheyen KL, Newton JR.Epidemiological studies into the risk factors for naturally-occurring equine laminitis are limited. There are a small number of such studies, although the results are inconsistent and remain disputed. The reasons for the conflicting results remain unclear. The aim of this review was to critically evaluate previous research in order to identify publications which provide the best evidence of risk factors for naturally-occurring equine laminitis. A systematic review of English language publications was conducted using MEDLINE (1950-2010), CAB Direct (1910-2010) and IVIS (1997-2010). Additional p...
Modulation of equine neutrophil adherence and migration by the annexin-1 derived N-terminal peptide, Ac2-26.
Veterinary immunology and immunopathology    November 19, 2011   Volume 145, Issue 1-2 214-222 doi: 10.1016/j.vetimm.2011.11.011
Brooks AC, Rickards KJ, Cunningham FM.Neutrophil activation, whilst a key component of host defence, must be tightly regulated in order to avoid an inappropriate cellular response. Annexin-1, which is present in large amounts in neutrophils, and its N-terminal peptides, reduce neutrophil accumulation but annexin peptides have also been shown to exhibit neutrophil activating properties. We have recently shown annexin-1 to be present in equine neutrophils and demonstrated that the annexin-1-derived peptide, Ac2-26, can both reduce superoxide production by these cells in response to other stimuli and directly induce free radical prod...
Equine degenerative myeloencephalopathy in Lusitano horses.
Journal of veterinary internal medicine    November 19, 2011   Volume 25, Issue 6 1439-1446 doi: 10.1111/j.1939-1676.2011.00817.x
Finno CJ, Higgins RJ, Aleman M, Ofri R, Hollingsworth SR, Bannasch DL, Reilly CM, Madigan JE.Equine degenerative myeloencephalopathy (EDM) is a neurodegenerative disorder that has been previously associated with low vitamin E concentrations. Objective: To describe the clinical, electrophysiologic, and pathologic features of EDM in a group of related Lusitano horses. Methods: Fifteen Lusitano horses. Methods: Neurologic examinations were conducted, and serum vitamin E concentrations were measured. Three neurologically abnormal horses were further evaluated by ophthalmologic examination, electroretinography, electroencephalography, muscle and nerve biopsies, and post-mortem examination....