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Clinical features and treatment of renal tubular acidosis in two horses.
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 294-296 
Ziemer EL, Parker HR, Carlson GP, Smith BP.Two horses were admitted separately for evaluation and treatment of profound hyperchloremic metabolic acidosis without azotemia. One, an 11-year-old Quarter Horse mare, had been depressed and ataxic for 2 days. The other, a 2-year-old Quarter Horse colt, had a 6-week history of depression, anorexia, and weight loss. Both horses responded to fluid and electrolyte therapy, but required daily oral administration of sodium bicarbonate for maintenance. In each case, the diagnosis was renal tubular acidosis.
Investigation into the use of narcotic antagonists in the treatment of a stereotypic behavior pattern (crib-biting) in the horse.
American journal of veterinary research    February 1, 1987   Volume 48, Issue 2 311-319 
Dodman NH, Shuster L, Court MH, Dixon R.Crib-biting in horses is a repetitive behavior pattern which may involve the activation of both narcotic receptors and dopamine receptors in the CNS. Crib-biting frequency, determined in 7 nontreated horses under controlled conditions, was usually linear for many hours and ranged from 0.3 to 14.9 bites/min. Intravenous or IM injections of narcotic antagonists decreased these rates to almost zero by about 20 minutes after the injection was given. The duration of the response to a single injection ranged from 20 minutes for naloxone to 4 hours or more for nalmefene and diprenorphine. Effective d...
Hemorrhagic fibrinonecrotic duodenitis-proximal jejunitis in horses: 20 cases (1977-1984).
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 311-315 
White NA, Tyler DE, Blackwell RB, Allen D.Records of 20 horses with small intestinal disease causing acute colic and affecting the proximal portion of the small intestine were examined retrospectively. The disease was characterized by severe to moderate pain, which was replaced by depression, fever, gastric reflux, slight distention of the affected small intestine, leukocytosis, and high concentrations of total protein in the peritoneal fluid. Grossly, the affected intestines were hemorrhagic and had yellow discoloration. Histopathologic findings included submucosal edema, neutrophilic infiltration of the submucosal and laminal propri...
Midline scrotal ablation technique for unilateral cryptorchid castration in horses.
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 283-285 
Palmer SE, Passmore JL.Thirty-nine unilateral cryptorchid horses were castrated, using a midline scrotal ablation technique. This approach was satisfactory to access both inguinal rings, to eliminate the need for 2 incisions, and to allow for completion of the surgery by primary closure. These horses recovered from surgery with few complications, returned to work promptly, and had excellent cosmetic results.
Renal tubular acidosis in two horses: diagnostic studies.
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 289-293 
Ziemer EL, Parker HR, Carlson GP, Smith BP, Ishizaki G.An 11-year-old Quarter Horse mare and a 2-year-old Quarter Horse colt with clinical diagnoses of renal tubular acidosis (RTA) were donated to the University of California Veterinary Medical Teaching Hospital. A series of diagnostic tests was performed in an attempt to characterize the type and cause of RTA in these horses. Endogenous creatinine clearance and sodium sulfanilate clearance were within reference ranges; thus, no abnormality of glomerular function was detected. To assess renal tubular function in response to acid loading, each horse was given 0.1 g of NH4Cl/kg of body weight via na...
Hybridoma cell lines secreting monoclonal antibodies against equine infectious anemia virus.
Journal of virological methods    February 1, 1987   Volume 15, Issue 3 177-185 doi: 10.1016/0166-0934(87)90096-6
Horenstein AL, Glait HM, Koss A.A monoclonal anti-equine infectious anemia virus (anti-EIAV) antibody (1B15) has been generated by fusion of X63 Ag 8.653 myeloma cells and spleen cells from mice hypersensitized with viral antigen p29. Ouchterlony double-diffusion analysis indicated that antibody 1B15 is of the IgG class. The specificity of the immune reaction for p29 was confirmed by cross-over immunoelectrophoresis and disc-gel electrophoresis. MAb 1B15 was used to devise a solid-phase 'capture' RIA for EIAV-p29 antigen. The antigen, bound by 1B15 adsorbed onto wells of flexible microtitre plates, was detected using a rabbi...
Equine zona pellucida and capsule: some physicochemical and antigenic properties.
Gamete research    February 1, 1987   Volume 16, Issue 2 121-132 doi: 10.1002/mrd.1120160204
Bousquet D, Guillomot M, Betteridge KJ.The capsule which surrounds the pre-attachment equine embryo has been compared with the zona pellucida (zp) that it replaces, as well as with the rabbit blastocyst coverings, by means of physicochemical and immunological methods. Trypsin solution at pH varying between 7.5 and 9.0 completely solubilized the capsule, as did Na borohydride. However, solutions of pH 2.0 or 12.0, urea, high temperature (65 degrees C, 60 min or 80 degrees C, 30 min), mercaptoethanol and dithiothreitol were able to solubilize the zp but not the capsule at the concentrations used. Indirect immunofluorescence on cryost...
Compression bone plating of a medial condylar fracture of the third metatarsal bone in a Thoroughbred filly.
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 305-307 
Bowman KF, Sweeney CL, Tate LP.A medial condylar fracture of the third metatarsal bone in a 2-year-old Thoroughbred filly was repaired successfully by use of compression bone plating. At discharge from the hospital, thickening of the metatarsus was evident, and proliferative changes were associated with the site of bone plate application. It was expected that these changes would limit the filly's use as a racehorse, and a return to training was not recommended. Especially in horses that may return to racing, use of compression bone plating initially should not replace stall rest or lag screw fixation treatment of this type ...
Ileocecocolic intussusception as a sequel to jejunocecostomy in a mare.
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 303-304 
Schumacher J, Hanrahan L.An excessively long ileal stump, the result of a previous jejunocecostomy, had intussuscepted into the cecum and subsequently obstructed the cecocolic orifice of a 12-year-old Quarter Horse mare. Clinical signs were dehydration, ileus, and endotoxemia. The diagnosis was made at necropsy.
Malignant teratoid medulloepithelioma in a horse.
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 301-302 
Szymanski CM.Enlargement of the left eye, corneal opacification, and blindness were clinical signs of a teratoid medulloepithelioma in a 5-year-old Standardbred mare. Diagnosis was made on histologic examination of the enucleated eye. Medulloepitheliomas are congenital intraocular tumors arising from primitive ciliary body epithelium. Their development is rare in domestic animals.
Traumatic tarsal luxation repaired without internal fixation in three horses and three ponies.
Journal of the American Veterinary Medical Association    February 1, 1987   Volume 190, Issue 3 297-300 
Moll HD, Slone DE, Humburg JM, Jagar JE.Three horses and three ponies were treated for traumatic luxation of the proximal intertarsal or tarsometatarsal joint. In each case, there were fractures of one or more tarsal bones. Three of the animals had disruption of one of the collateral ligaments. Five animals were treated by closed reduction and external coaptation. One pony was treated by open curettage, a cancellous bone graft, and cast immobilization. No internal fixation was used in any of these animals. From this series of cases, it would appear that closed reduction and external coaption alone is adequate treatment for most case...
Distribution and implications of beta-endorphin and ACTH-immunoreactive cells in the intermediate lobe of the hypophysis in healthy equids.
American journal of veterinary research    February 1, 1987   Volume 48, Issue 2 323-327 
Amann JF, Smith RM, Ganjam VK, Paull WK, McClure RC, Green EM, Garner HE.The distribution of cells that stain positive for beta-endorphin and ACTH immunoreactivity was studied in the pars intermedia (PI) of the hypophysis in 3 healthy horses and 2 healthy ponies. Serial sections treated with commercial antibodies generated against beta-endorphin or ACTH were processed for immunocytochemical studies, using the avidin biotin immunoperoxidase-complex method. Distribution patterns of cells reacting with antibodies were similar in cells from all equids. Cells immunostained for ACTH were numerous and widely distributed in the PI. Cells immunopositive for ACTH probably co...
Arterial hypotension and the development of postanesthetic myopathy in halothane-anesthetized horses.
American journal of veterinary research    February 1, 1987   Volume 48, Issue 2 192-197 
Grandy JL, Steffey EP, Hodgson DS, Woliner MJ.The effect of halothane-induced hypotension on the development of postanesthetic myopathy was studied, using 6 healthy adult horses. Horses were anesthetized with halothane in oxygen for 3.5 hours on each of 2 occasions. Intermittent positive-pressure ventilation was used to maintain PaCO2 of 45 to 55 mm of Hg throughout both anesthetic exposures. By regulating the inspired halothane concentration, a mean arterial blood pressure of 85 to 95 mm of Hg (normotension) was maintained throughout the 1st anesthetic exposure, and a mean arterial blood pressure of 55 to 65 mm of Hg (hypotension) was ma...
Effects of stallion seminal plasma on hydrogen peroxide release by leukocytes exposed to spermatozoa and bacteria.
Journal of reproductive immunology    February 1, 1987   Volume 10, Issue 2 157-166 doi: 10.1016/0165-0378(87)90073-8
Hansen PJ, Hoggard MP, Rathwell AC.The ability of stallion seminal plasma to modify phagocytosis of spermatozoa and Streptococcus zooepidemicus was examined. Phagocytosis was monitored indirectly as the H2O2 produced by peripheral blood leukocytes after addition of spermatozoa or bacteria. Hydrogen peroxide production after addition of ejaculated spermatozoa was greater (P less than 0.01) than after addition of epididymal sperm. Furthermore, pre-incubation of epididymal sperm with 6.25-50% seminal plasma caused a dose-dependent increase in subsequent H2O2 production by leukocytes (P less than 0.05). In addition, equine serum wa...
The ELY-1 locus controls a di-allelic alloantigenic system on equine lymphocytes.
Journal of immunogenetics    February 1, 1987   Volume 14, Issue 1 59-71 doi: 10.1111/j.1744-313x.1987.tb00363.x
Byrns G, Crump AL, Lalonde G, Bernoco D, Antczak DF.The ELY-1 locus controls the expression of a polymorphic cell surface antigen of equine lymphocytes which was detected using antibodies generated by alloimmunization with peripheral blood lymphocytes. The ELY-1 antigens were not detected on erythrocytes or platelets by absorption experiments. The two alleles, which have been designated ELY-1.1 and ELY-1.2, are expressed codominantly and appear to constitute a closed system at the population level. In family studies, the ELY-1 antigens segregated as products of an autosomal locus not linked to the major histocompatibility complex (MHC) of the h...
Pythium insidiosum sp. nov., the etiologic agent of pythiosis.
Journal of clinical microbiology    February 1, 1987   Volume 25, Issue 2 344-349 doi: 10.1128/jcm.25.2.344-349.1987
De Cock AW, Mendoza L, Padhye AA, Ajello L, Kaufman L.Pythium insidiosum sp. nov., the etiologic agent of pythiosis, a cosmopolitan disease of horses, cattle, and dogs, is described and illustrated.
Effects of xylazine on equine intestinal vascular resistance, motility, compliance, and oxygen consumption.
American journal of veterinary research    February 1, 1987   Volume 48, Issue 2 198-203 
Stick JA, Chou CC, Derksen FJ, Arden WA.Isolated jejunal segments were perfused at a constant blood flow rate to determine simultaneously the effects of xylazine on intestinal vascular resistance, motility, compliance, and oxygen consumption in 12 anesthetized ponies. Xylazine was infused into the artery perfusing the intestinal segment (group 1), or into the jugular vein as a single IV bolus (group 2), or 3 times as IV boluses repeated at 10-minute intervals (group 3). Dose-response curves in group 1 indicated a biphasic response to the drug with vasoconstriction, increased motility, and increased oxygen consumption at lower doses ...
Evaluation for veterinary use of the Chiltern box: a device for home electrocardiographic monitoring.
The Veterinary record    January 24, 1987   Volume 120, Issue 4 85-87 doi: 10.1136/vr.120.4.85
Brownlie SE.The Chiltern Box is a small electrocardiograph designed for home monitoring of human patients. Its veterinary application has been investigated in the dog, the cat and the horse. It has been useful in the diagnosis of previously undiagnosed dysrhythmias in dogs showing signs of exercise intolerance and syncope.
Failure of ketamine to induce anesthesia in two horses.
Journal of the American Veterinary Medical Association    January 15, 1987   Volume 190, Issue 2 201-202 
Trim CM, Adams JG, Hovda LR.No abstract available
Ehrlichia equi infection in a foal.
Journal of the American Veterinary Medical Association    January 15, 1987   Volume 190, Issue 2 199-200 
Ziemer EL, Keenan DP, Madigan JE.No abstract available
Methiocarb poisoning in a horse.
The Veterinary record    January 10, 1987   Volume 120, Issue 2 47 doi: 10.1136/vr.120.2.47-a
Alexander KA.No abstract available
The use of a bovine plasma progesterone ELISA kit to measure progesterone in equine, ovine and canine plasmas.
The Veterinary record    January 3, 1987   Volume 120, Issue 1 5-8 doi: 10.1136/vr.120.1.5
Eckersall PD, Harvey MJ.A commerical kit designed to measure the concentration of progesterone in bovine plasma using an enzyme-linked immunosorbent assay (ELISA) has been assessed for measuring progesterone in the plasma of horses, sheep and dogs. Without validation, an immunoassay developed for progesterone in one species should not be used to measure progesterone in the plasma of other species. The kit was assessed by using the criteria of parallelism to a standard curve, the recovery of added progesterone, the correlation with an established radioimmunoassay and the detection of physiological change for each of t...
Phagocytosis of horse erythrocytes treated with equine infectious anemia virus by cultivated horse leukocytes.
Archives of virology    January 1, 1987   Volume 95, Issue 1-2 67-77 doi: 10.1007/BF01311335
Sentsui H, Kono Y.Horse erythrocytes treated with equine infectious anemia virus hemagglutinin were phagocytized by cultivated horse leukocytes (mainly macrophage-like cells and partly polymorphonuclear cells) after incubation with fresh horse serum but not with inactivated horse serum. The phagocytosis began as soon as the erythrocytes were added to the leukocyte cultures, and the majority of the reaction proceeded within 30 minutes. Addition of antiserum showed a slightly suppressing but no enhancing effect on the phagocytosis. Phagocytosis seemed to be caused by the recognition of the third complement compon...
Reproductive wastage in the mare and its relationship to progesterone in early pregnancy.
Journal of reproduction and fertility. Supplement    January 1, 1987   Volume 35 493-495 
Forde D, Keenan L, Wade J, O'Connor M, Roche JF.No abstract available
Joint report of the Fourth International Workshop on Lymphocyte Alloantigens of the Horse, Lexington, Kentucky, 12-22 October 1985.
Animal genetics    January 1, 1987   Volume 18, Issue 1 81-93 
No abstract available
Use of different nonglycolysable sugars to maintain stallion sperm viability when frozen or stored at 37 degrees C and 5 degrees C in a bovine serum albumin medium.
Journal of reproduction and fertility. Supplement    January 1, 1987   Volume 35 135-141 
Arns MJ, Webb GW, Kreider JL, Potter GD, Evans JW.Bovine serum albumin (BSA) diluents containing lactose, raffinose or sucrose were not different (P greater than 0.05) in their ability to maintain stallion sperm viability, as determined by percentage motile spermatozoa (PMS) and their rate of forward movement (RFM), when stored at 37 or 5 degrees C for 24 h. These diluents did promote a higher (P greater than 0.05) PMS and RFM, when compared with BSA diluents containing arabinose or galactose. The BSA-arabinose and BSA-galactose diluents did not differ (P less than 0.05) in their ability to support sperm viability and were detrimental to sper...
Concentrations of uterine luminal prostaglandins in mares with acute and persistent endometritis.
Equine veterinary journal    January 1, 1987   Volume 19, Issue 1 31-37 doi: 10.1111/j.2042-3306.1987.tb02574.x
Watson ED, Stokes CR, David JS, Bourne FJ, Ricketts SW.Intrauterine infusion of 1 per cent oyster glycogen solution was used to induce acute endometritis in four genitally normal mares. Numbers of viable neutrophils recovered in uterine washings had increased by 1 h after infusion and remained elevated for at least 72 h. There was a significant correlation between numbers of viable neutrophils and total protein concentrations and between prostaglandin (PG)F and PGE2 concentrations in washings. There was also a significant relationship between concentrations of 15-keto-13, 14-dihydro PGF2 alpha in plasma and PGF in washings. Intrauterine concentrat...
Use of flotation tanks for the treatment of seven cases of skeletal injury in horses.
Equine veterinary journal    January 1, 1987   Volume 19, Issue 1 73-77 doi: 10.1111/j.2042-3306.1987.tb02588.x
Hutchins DR, McClintock SA, Brownlow MA.No abstract available
Observations and management of fractures of the proximal phalanx in young Thoroughbreds.
Equine veterinary journal    January 1, 1987   Volume 19, Issue 1 43-49 doi: 10.1111/j.2042-3306.1987.tb02579.x
Ellis DR, Simpson DJ, Greenwood RE, Crowhurst JS.A retrospective study of 119 cases of fracture of the proximal phalanx is described. The short incomplete sagittal fracture (split pastern) was most common and carried a good prognosis for a return to racing following conservative treatment. Longer incomplete fractures also had a good prognosis but complete fractures, either through the lateral cortex of the proximal phalanx or through the bone into the proximal interphalangeal joint, required internal fixation. Careful assessment of these and comminuted fractures was essential before surgery was undertaken. Most comminuted fractures were trea...
Effect of Salmonella typhimurium endotoxin on PGF-2 alpha release and fetal death in the mare.
Journal of reproduction and fertility. Supplement    January 1, 1987   Volume 35 485-492 
Daels PF, Starr M, Kindahl H, Fredriksson G, Hughes JP, Stabenfeldt GH.The infusion of Salmonella typhimurium endotoxin into pregnant mares resulted in a biphasic release pattern of PGF-2 alpha as determined by 15-keto-13,14-dihydro-PGF-2 alpha concentrations. The initial phase of 1 h duration was followed by accentuated release by 2 h after infusion; concentrations reached basal levels by 6 h. In 7 mares at 23, 26, 29, 33, 36, 53 and 55 days of gestation, fetal death occurred between 36 and 120 h after infusion; 12 mares at 46, 51, 56, 59, 65, 71, 73, 85, 103, 138, 283 and 318 days of gestation did not abort after endotoxin infusion. Luteal activity was compromi...