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Topic:Disease Transmission

Disease transmission in horses refers to the spread of infectious agents such as bacteria, viruses, fungi, and parasites among equine populations. These pathogens can be transmitted through various routes, including direct contact, vector-borne transmission, or environmental exposure. Factors influencing disease transmission include horse density, management practices, and biosecurity measures. Understanding the mechanisms and conditions that facilitate the spread of diseases is essential for developing effective prevention and control strategies. This page compiles peer-reviewed research studies and scholarly articles that investigate the modes of transmission, risk factors, and management practices related to infectious diseases in horses.
Prevalence, risk factors, and antimicrobial resistance of Staphylococcus aureus in equines in Egypt.
Scientific reports    June 3, 2026   Volume 16, Issue 1 17125 doi: 10.1038/s41598-026-55462-4
El-Halim MOA, Shoraba M, Gattan HS, Alruhaili MH, Selim A.Staphylococcus aureus is a common commensal organism in both humans and animals, frequently colonizing the skin and nasal cavities of healthy individuals, although it can also cause a wide range of severe infections. The present study investigated the prevalence and risk factors of S. aureus in equines, along with antimicrobial resistance patterns of methicillin-resistant S. aureus (MRSA) isolates. The results revealed a prevalence of 38.6% in nasal samples collected from equines, highlighting the organism's significant presence and potential to cause infections in these animals. A genotypic p...
Molecular and parasitological evidence of Leishmania (Mundinia) martiniquensis infection in a horse from Brazil.
International journal for parasitology    June 3, 2026   104898 doi: 10.1016/j.ijpara.2026.104898
Franco Leonel JA, Silva MDD, Araujo AC, Vioti G, Borges Martins JP, Strefezzi RF, Galvis-Ovallos F, Bianchi Galati EA, Ferreira de Sousa Oliveira TM.Leishmania (Mundinia) martiniquensis is an emerging human pathogen with increasing reports of infection in domestic animals. This study describes a naturally infected mare from Brazil with no history of international travel, presenting with persistent nodular cutaneous lesions and cervical lymph node enlargement, without evidence of systemic involvement. Considering the endemicity of cutaneous and visceral leishmaniasis in the study area, as well as previous reports of equine leishmaniasis, infection by Leishmania (Leishmania) infantum was initially suspected. Anti-L. (L.) infantum antibodies ...
Viral Hepatitis.
The Veterinary clinics of North America. Equine practice    June 3, 2026   S0749-0739(26)00021-0 doi: 10.1016/j.cveq.2026.04.006
Tomlinson J.Since 2012, 2 viral causes of hepatitis have been identified in horses. Much remains to be discovered about their transmission, risk factors for clinical disease, diagnosis, and treatment approaches. Equine parvovirus-hepatitis has been identified as the cause of acute hepatic necrosis, previously known as Theiler's disease. Equine hepacivirus is recognized as a cause of chronic fibrosing hepatitis. Diagnosis relies on ruling out other causes of hepatitis and documenting infection by serum or liver polymerase chain reaction. There is no direct antiviral for either condition and treatments are ...
West Nile Virus in Horses as a Sentinel Host in One Health Surveillance: Epidemiological Insights and Future Perspectives.
Microorganisms    June 3, 2026   Volume 14, Issue 6 1263 doi: 10.3390/microorganisms14061263
West Nile virus (WNV) is a globally distributed mosquito-borne flavivirus with significant implications for both veterinary and public health. While horses are incidental dead-end hosts, their epidemiological role extends beyond clinical disease, as they can serve as effective sentinel hosts for detecting local viral circulation. Their frequent exposure to mosquito vectors, ability to mount measurable antibody responses, geographic stability, accessibility for monitoring, and the possibility of observation within managed owner-veterinarian systems make them particularly suitable for surveillan...
Herd-level occurrence and spread of Theileria equi and its associated ticks on an Austrian horse farm.
Veterinary parasitology, regional studies and reports    May 30, 2026   Volume 72 101509 doi: 10.1016/j.vprsr.2026.101509
Pikalo J, Hartl B, Stimac I, Barogh BS, Fuehrer HP, Joachim A.Equine piroplasmosis (EP) is a tick-borne disease caused by the blood parasites Theileria equi, Theileria haneyi, and Babesia caballi transmitted primarily by hard ticks (Ixodidae). The clinical courses of EP range from asymptomatic to severe, and chronic infections for several years support the transmission among hosts. Methods: Over a period of two years, blood and fecal samples were taken from horses (n = 18) on a single farm in eastern Austria, starting with the first confirmed case of T. equi infection. Hard ticks (n = 1525 of Ixodes ricinus, Dermacentor reticulatus and Haemaphysalis ...
Integrative and conjugative elements carrying high-level gentamicin resistance genes in Streptococcus dysgalactiae subsp. equisimilis from horses.
Microbial genomics    May 27, 2026   Volume 12, Issue 5 001722 doi: 10.1099/mgen.0.001722
Rochegüe T, Hughes S, Saras E, Gillet B, Drapeau A, Glaser P, Madec JY, Haenni M, Lupo A.In streptococci, the acquisition of high-level gentamicin resistance (HLGR) abolishes the synergy with beta-lactams, constituting a medical concern for humans and animals. This synergy between gentamicin and beta-lactams is useful to treat severe infections like endocarditis, among others. HLGR has been characterized mostly in roup B Streptococci mediated by the bi-functional gene (6)-(2).HLGR- subsp. () (=27) were isolated from the uterus of mares during a routine screening before fecundation. One HLGR- was isolated from a lymph node of a mare. The mares resided in six different studs locat...
Isolation and Identification of Emerging Equine Encephalosis Virus Serotype 6 in Israel, 2023.
Pathogens (Basel, Switzerland)    May 27, 2026   Volume 15, Issue 6 571 doi: 10.3390/pathogens15060571
Golender N, Mildenberg Z, Bellaiche M, Hoffmann B.Equine encephalosis (EE) is an arthropod-borne viral disease resembling a mild form of African horse sickness disease, which affects all species of equids. Previously, only EEV serotype 4 (EEV-4) caused sporadic outbreaks of the disease in Israel. In the summer of 2023, EE was clinically diagnosed in horses and donkeys in Israel. For laboratory confirmation, tissue cultures were inoculated with whole-blood samples obtained from sick animals. Five EEV isolates were successfully recovered in tissue and confirmed by conventional RT-PCR and Sanger sequencing of several viral genes. BLAST analysis ...
Surveillance of equine glanders in India (2019-2023): Prevalence estimate, risk analysis and future strategy.
Microbial pathogenesis    May 26, 2026   Volume 217 108597 doi: 10.1016/j.micpath.2026.108597
Singha H, Shanmugasundaram K, Jhandai P, Rani R, Yashpal , Mandal BN, Kanani A, Shah N, Bhatt L, Khasa V, Koul R, Amandeep , Tapase J, Parnam S....Equine glanders, a notifiable zoonotic disease caused by Burkholderia mallei, continues to pose a significant health and regulatory challenge in India. This study summarizes the outcomes of a nationwide sero surveillance programme conducted between January 2019 and December 2023 to assess the distribution and temporal trends of glanders in equid populations. A total of 158,798 serum samples collected from 391 districts across 19 states and three union territories were screened using Hcp1-based indirect ELISA, followed by confirmatory testing through the complement fixation test. During the fiv...
Theileria equi sensu lato genetic diversity and phylogeny: new insights from mitochondrion, apicoplast and nucleus multilocus gene analysis.
Ticks and tick-borne diseases    May 22, 2026   Volume 17, Issue 3 102656 doi: 10.1016/j.ttbdis.2026.102656
Mège M, Berquier F, Bonsergent C, Malandrin L.Equine piroplasmosis is a significant tick-borne disease with a global distribution. Among the two causative agents, Theileria equi has undergone numerous taxonomic reclassifications over time, reflecting advances in our understanding of its biology, molecular characteristics, and phylogenetic relationships. Formerly named Babesia equi, now classified in the Equus group apart from Babesia and Theileria species, its genus name will again certainly change. The genetic diversity also within T. equi lead to the renaming of one lineage as Theileria haneyi. Theileria equi should better now be consid...
An epizootic of equine viral arteritis at a Thoroughbred racetrack in Illinois: 223 cases. Foreman JH, Scollay MC.An epizootic of equine viral arteritis (EVA) occurred over an 8-wk period in the summer of 1993 at a midwestern Thoroughbred (TB) racetrack that ceased operations in 2021. Based on clinical signs, viral isolation, and serology, 223 horses (213 TBs, 10 lead ponies) were affected. Consistent clinical signs included fever (38.3-40.6°C; 101-105°F), depression, inappetence, and diffuse urticaria, including distal limb and preputial edema. Equine arteritis virus (EAV) was cultured from buffy coat samples from 24 of 28 acutely ill horses. Seventeen of 18 convalescent horses and 1 of 92 non-affected...
Growth kinetics of Taylorella equigenitalis and its survival in straw-based bedding.
Veterinary research communications    May 19, 2026   Volume 50, Issue 4 331 doi: 10.1007/s11259-026-11278-1
Florianova M, Krzyzankova M, Korena K, Juricova H.Taylorella equigenitalis, the causative agent of contagious equine metritis, is a fastidious bacterium with limited tolerance to extra-host conditions; however, quantitative data on its growth dynamics and survival outside the host remain scarce. This study evaluated the growth of T. equigenitalis under aerobic and microaerophilic conditions in liquid medium and its survival in wet and dry straw-based bedding under controlled laboratory conditions.Growth was assessed at 20 °C and 37 °C using real-time optical density monitoring and viable cell counts. No proliferation was observed at 20 Â...
Genetic diversity of Dermacentor nitens (Acari: Ixodidae) collected on horses from western Cuba.
Journal of medical entomology    May 17, 2026   Volume 63, Issue 3 tjag059 doi: 10.1093/jme/tjag059
Roblejo-Arias L, Diaz-Sánchez AA, Marrero-Perera R, Lobo-Rivero E, Corona-González B, Chilton NB.The tropical horse tick, Dermacentor nitens Neumann, 1897, has a wide distribution throughout the Neotropics, and is a vector of protozoan haemoparasites that cause equine piroplasmosis. Despite this, little is known about the genetic diversity of this tick species, particularly in Cuba, where horses are important domestic animals used in agriculture and for transportation. The objective of this study was to assess the magnitude of genetic variation in 115 D. nitens adults (57 females and 58 males) collected from horses in the Cuban province of Mayabeque using sequence data of two mitochondria...
Exposure in Horses to Human Tick-Borne Relapsing Fever Agent Borrelia persica, Israel, 2025.
Emerging infectious diseases    May 12, 2026   Volume 32, Issue 5 749-752 doi: 10.3201/eid3205.251283
Shwartz D, Haras L, Nachum-Biala Y, Tirosh-Levy S, Steinman A, Baneth G.Human tick-borne relapsing fever caused by Borrelia persica is common in western Asia. A survey of 301 horses in Israel revealed 9.96% seropositivity toward B. persica antigens; 1 horse (0.33%) was also PCR positive for B. persica DNA. Phylogenetic analysis supported a transmission cycle involving ticks, humans, and horses.
Vaginal host-microbe signatures linked to placental outcomes in mares.
Equine veterinary journal    May 10, 2026   doi: 10.1002/evj.70185
van Heule M, Heil B, Norris JK, Gedye K, Lin X, De Spiegelaere W, Daels P, Dini P.Ascending placentitis is a leading cause of late-term pregnancy loss in mares. Although pathogens are presumed to ascend from the caudal reproductive tract, the association between the vaginal microbiome and placentitis has not been systematically examined. Objective: To characterise microbial and host gene expression in the equine vagina during gestation and to identify taxa or transcripts that were associated with the presence of an abnormal placenta at birth. Methods: Prospective, paired observational study. Methods: Vaginal wall swabs were collected from 49 multiparous Thoroughbred mares a...
First confirmed report of equine coital exanthema in Uruguayan horses.
Veterinary research communications    May 9, 2026   Volume 50, Issue 4 310 doi: 10.1007/s11259-026-11261-w
Machado M, Alves M, Coubrough C, Queiroz-Machado CRR, Barrandeguy M, Vissani A, Carossino M, Menchaca A.Equine Coital Exanthema (ECE) is a contagious venereal disease caused by Equid alphaherpesvirus 3 (EHV‑3). Although ECE is self-limiting, it causes significant economic losses to the global equine industry due to the temporary segregation of affected mares and stallions from breeding activities. This report describes the epidemiological, clinical, histological, and molecular findings from an outbreak of ECE in Uruguayan horses. Seven days following the introduction of a stallion, five mares developed extensive papular and vesicular dermatitis in the vaginal and perineal regions. The stallion...
The impact of barefoot racing in young Swedish trotters on career length.
Journal of animal science    May 8, 2026   skag127 doi: 10.1093/jas/skag127
Berglund P, Andonov S, Strandberg E, Eriksson S.In several European countries, racing without shoes, i.e., barefoot, is a common strategy in trotting races to improve the speed of the horse. Why some trotters can race barefoot without damage to the hoof from excessive wear and others cannot, has been shown to partly be explained by differences in hoof composition. In particular, durable hind hooves are believed to be important to sustain racing without shoes. Also, variation in the proportion of the races the horse races with barefoot hind hooves, has been shown to be affected by genetic differences in Swedish Standardbred trotters (SB) and...
Detection of papillomavirus DNA in uterine flushing samples from healthy mares reveals diverse genotypes with differing host ranges.
Scientific reports    May 8, 2026   Volume 16, Issue 1 21179 doi: 10.1038/s41598-026-52384-z
A molecular study to assess the presence of some papillomaviruses was performed on 105 uterine flushing samples of healthy mares using real time quantitative polymerase chain reaction (qPCR) and digital PCR (dPCR). Bovine, equine, and ovine papillomavirus DNA was detected in 27 uterine flushing samples through dPCR (~ 25.71%); qPCR was able to detect 18 positive samples (~ 17.14%). Differences between the two molecular protocols were significant as shown by McNemar's test (p˂ 0.005). EcPV DNA was detected in 10 samples by dPCR (~ 9.52%) of uterine flushing samples. qPCR detected EcPV DN...
Molecular detection of pathogenic Leptospira spp. in mares with reproductive disorders enrolled in embryo transfer programs.
Journal of equine veterinary science    May 7, 2026   105926 doi: 10.1016/j.jevs.2026.105926
Pinto GOA, Raymundo EF, da Silva GG, Santos AS, Correia DS, Xavier GR, Samico-Fernandes EFT, Carneiro GF, Azevedo MIND, Mota RA.Equine genital leptospirosis (EGL) is associated with reproductive disorders in mares. However, its occurrence in embryo transfer (ET) programs remains poorly characterized. Objective: Given the scarcity of data on the circulation of Leptospira spp. in mares enrolled in ET programs, this study aimed to investigate the serological and molecular occurrence of Leptospira spp. in mares with a history of reproductive disorders from 13 stud farms dedicated to embryo transfer in Brazil. Methods: Serum and endometrial cytobrush samples (ECS) were collected from 70 unvaccinated mares. Serological analy...
Genetic diversity of Toxoplasma gondii isolates from members of the families camelidae and equidae worldwide: a systematic review.
Irish veterinary journal    May 7, 2026   doi: 10.1186/s13620-026-00344-4
Hataminejad M, Lashaki EK, Behboudi E, Esmaeili B, Ahmadi S, Galeh TM.Toxoplasma gondii is an apicomplexan parasite with a global distribution and significant public health and veterinary treatment implications. The present systematic review collates worldwide information on the genotypic diversity of T. gondii isolates infecting Camelidae (camels, alpacas, llamas, etc.) and Equidae (horses, donkeys, zebras, mules, etc.) and highlights their potential role as sentinels of environmental contamination and zoonotic spread. An exhaustive literature search of six electronic databases (PubMed, Web of Science, Scopus, ProQuest, Science Direct, and Google Scholar) from ...
Global prevalence and epidemiological determinants of African horse sickness: A systematic review and meta-analysis.
Veterinary journal (London, England : 1997)    May 4, 2026   106698 doi: 10.1016/j.tvjl.2026.106698
Purnama MTE, Firdausy LW, Fikri F, Wicaksono AP, Maslamama ST, Wardhani LDK.African horse sickness (AHS) is a highly fatal, vector-borne viral disease of equids with substantial economic and animal health impacts, particularly in endemic regions. Despite numerous epidemiological studies, reported prevalence estimates remain highly variable, and a comprehensive quantitative synthesis is lacking. This study aimed to systematically evaluate and synthesize the global prevalence of AHS and to identify sources of epidemiological heterogeneity. A systematic review and meta-analysis were conducted following PRISMA 2020 guidelines, with the protocol registered in the Open Scie...
Accuracy of large language model-based artificial intelligence tools for equine topics.
Journal of equine veterinary science    May 1, 2026   105924 doi: 10.1016/j.jevs.2026.105924
Aldworth-Yang S, Coleman SJ, O'Reilly K, Catalano DN.Artificial intelligence (AI) platforms are becoming increasingly popular as resources for equine information. However, these platforms generate responses from a wide range of sources and do not always distinguish between fact and opinion. Objective: The objective of this study was to assess the accuracy and quality of AI-generated answers to equine-related questions. Researchers hypothesized that AI platforms could answer basic equine questions effectively but would perform poorly on complex topics or questions. Methods: Forty questions were written covering general horse care, facilities mana...
Molecular and serological survey on Theileria equi and Babesia caballi infecting Arabian horses in the northern provinces of Syria.
Open veterinary journal    April 30, 2026   Volume 16, Issue 4 2203-2211 doi: 10.5455/OVJ.2026.v16.i4.22
Abdaljwad M, Al-Sabi MNS, Shawaf T, Mokahwi AA, Alfares W, Abdalkader A.Equine babesiosis is one of the prevalent diseases in horses worldwide, but its presence in Syria generally and in the northern region specifically is not known. In Syria, the civil war has severely disrupted veterinary services, hence disease control measures, creating a fertile ground for the spread of tick-borne diseases. Unassigned: This study aimed to conduct a comprehensive molecular and serological survey of and . in Arabian horses from the northern provinces of Syria, regions heavily impacted by the war. Unassigned: A total of 110 Arabian horses, aged between 2 and 10 years, were inc...
Horse racing towards antibiotic resistance. Accompanying animals as a source of antibiotic-resistant bacteria.
Journal of applied genetics    April 29, 2026   doi: 10.1007/s13353-026-01053-y
Lepianka A, Sitkiewicz I.Antibiotic resistance is a significant issue in modern infectious medicine and veterinary science, with animals, including horses, playing a crucial role in its dissemination. Antibiotics, used both for treatment and prevention of diseases in animals, influence the composition of the microbiota and promote the selection of resistant strains that can be transmitted to humans through direct or environmental contact. Horses, currently classified as companion animals, serve as a reservoir of commensal and pathogenic bacteria, including multidrug-resistant strains capable of horizontal gene transfe...
Equine sentinels and one health: a comprehensive serological survey of Crimean-Congo hemorrhagic fever virus in southeastern and Central Europe.
Frontiers in veterinary science    April 24, 2026   Volume 13 1810641 doi: 10.3389/fvets.2026.1810641
Italiya J, Nekudova P, Vaclavek P, Rusenova NV, Rusenov AG, Mihalca AD, Bărbuceanu F, Vuta VB, Hristescu DV, Modry D, Hensley LE, Rimoin AW, Zurek L.Crimean-Congo hemorrhagic fever (CCHF) is the widespread tick-borne viral disease affecting humans with endemic circulation across Africa, Asia, Eastern and Southern Europe. Climate change, global travel, and animal trade have accelerated the expansion of spp., the primary tick vectors of CCHF, into previously non-endemic areas, including the Czech Republic. To assess the current distribution of CCHF in equids across Southeastern and Central Europe, we screened serum samples from horses and donkeys from Bulgaria ( = 579), Romania ( = 1,534), and the Czech Republic ( = 576) by the ...
Glanders: Past, Present and Future of a Neglected Zoonosis as a Threat in Veterinary and Human Health.
Veterinary medicine and science    April 21, 2026   Volume 12, Issue 3 e70950 doi: 10.1002/vms3.70950
Kanani Y, Oryan A, Derakhshandeh A.Burkholderia mallei is the causative agent of glanders, a serious zoonotic disease of major concern for both animal and human health. This highly contagious and potentially fatal bacterium is always classified as a biothreat agent. In this review, we covered a comprehensive overview of glanders, including the biology of the pathogen, epidemiology, pathogenesis, diagnosis, control strategies and ongoing eradication programs in Eurasia. We also summarized human case reports, differential diagnosis, treatment and organism's antimicrobial properties. The section on vaccine development is among the...
Autochthonous Leishmaniosis in Dogs, Cats, Horses, and Wildlife in the United States of America.
Microorganisms    April 20, 2026   Volume 14, Issue 4 930 doi: 10.3390/microorganisms14040930
Yao C, Yang Y, Du A.Leishmaniasis is endemic in 99 countries worldwide, including the United States of America (USA). Its causative pathogens, spp. have been detected in both humans and animals within the USA. Lately, we have comprehensively reviewed autochthonous leishmaniasis in humans in this region. Animals play a pivotal role in maintaining its endemicity in some endemic areas and regions, for example, dogs in Brazil and the Mediterranean. In this review, we thoroughly examine autochthonous leishmaniosis in dogs, cats, horses, and wildlife in the USA, and we synthesize integration across species, transmissi...
Multivalent Disabled Infectious Single Animal (DISA)-DIVA vaccine for all nine serotypes of African horse sickness virus (AHSV) is broadly protective in IFNAR (-/-) mice.
Veterinary research    April 16, 2026   doi: 10.1186/s13567-026-01753-7
Utrilla-Trigo S, Jiménez-Cabello L, van Gennip RGP, van Rijn PA, Ortego J, Calvo-Pinilla E.African horse sickness (AHS) is a highly severe, midge-borne disease of equids showing a mortality rate of > 90% in naive domestic horses. Outbreaks are caused by AHS virus (AHSV) and result in devastating economic losses in developing countries as equids play a crucial role in the agricultural industry and many households. The AHSV species encompasses nine serotypes showing no or limited cross protection, which is challenging regarding AHS vaccine development. Recently, and like bluetongue virus (BTV), the AHS Disabled Infectious Single Animal (DISA)-DIVA vaccine platform was developed...
Comprehensive molecular characterization of Theileria equi: Detection, genetic diversity, and risk factors assessment.
Experimental parasitology    April 11, 2026   109135 doi: 10.1016/j.exppara.2026.109135
Maharana BR, Ganguly A, Malik R, Kumar A, Khanna S, Kumar B, Potliya S, Singh H, Dash A, Sahu S.Equine piroplasmosis, caused by Theileria equi, has been widely studied globally, but genetic diversity research in India remains limited. Analysis of 306 horse blood samples revealed T. equi infection in 10.78% by microscopy and 21.24% by PCR. Universal primers targeting 18S rRNA of T. equi and Babesia caballi were used, followed by species-specific primers generating 435 bp amplicons. Sequenced PCR-positive samples revealed high homology (99.52-100% in India, 95.89-100% globally), with all Indian isolates classified as genotype A. The EMA-1 gene phylogenetic analysis confirmed the insights f...
Equine Salmonella in Argentina: Genetic relatedness with humans and other animal species and first detection of serovar Freetown.
Comparative immunology, microbiology and infectious diseases    April 10, 2026   Volume 127 102469 doi: 10.1016/j.cimid.2026.102469
Salmonellosis in horses can cause severe enteritis with diarrhea, fever, and colic, which is usually severe in foals and hospitalized or immunocompromised animals. Carrier horses may intermittently shed Salmonella, thereby acting as a source of infection for other animals and humans. The aim of this study was to investigate the occurrence and molecular subtyping of Salmonella spp. in horses from Argentina, focusing on potential zoonotic relevance. Only a single isolate (S. Newport) was obtained from fecal samples of 249 clinically healthy horses (2018-2022), indicating a very low carrier detec...
From Horses to Zebras, an Update in Small Animal Respiratory Medicine.
The Veterinary clinics of North America. Small animal practice    April 8, 2026   S0195-5616(26)00023-9 doi: 10.1016/j.cvsm.2026.03.002
Dear JD.No abstract available