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Topic:Equine Medicine

Equine Medicine encompasses the study and application of medical practices specifically related to the health and well-being of horses. This field involves the diagnosis, treatment, and prevention of diseases and disorders affecting equine species. It covers a wide range of topics, including internal medicine, surgery, reproduction, and pharmacology. Research in equine medicine often focuses on understanding the physiological and pathological processes unique to horses, as well as developing effective therapeutic interventions. This page aggregates peer-reviewed research studies and scholarly articles that explore various aspects of equine medicine, providing insights into the latest advancements and methodologies in the care and management of horse health.
Leptomeningeal dissemination of a poorly differentiated carcinoma involving the trigeminal ganglion in a horse: a case report.
Journal of equine veterinary science    August 8, 2026   106123 doi: 10.1016/j.jevs.2026.106123
Rocha CSV, Ferreira CS, Jesus CVA, Silveira MDL, Gomes KMC, Júnior VAS, Gobbi FP, Fonseca SR, Oliveira AAF.Neoplastic conditions involving cranial nerves are uncommon in horses and represent a significant diagnostic challenge. Leptomeningeal dissemination is a recognized mechanism of tumor progression in aggressive neoplasms but is rarely reported in this species. A 15-year-old mixed-breed horse with a history of periocular squamous cell carcinoma treated by enucleation three years earlier developed progressive neurological signs. Initial differential diagnoses included metastatic neoplasia and equine protozoal myeloencephalitis. Due to rapid neurological deterioration, euthanasia and necropsy were...
The effect of intravenous fluids administered prior to competition: A randomized clinical.
Journal of equine veterinary science    August 8, 2026   106121 doi: 10.1016/j.jevs.2026.106121
Weintraub L, Fielding CL, Carli I, Greene-Dittz G.Administration of intravenous fluids prior to competition is common at major equestrian competitions, yet few studies have evaluated the benefits of this practice. Objective: The hypothesis was that pre-ride intravenous fluid therapy would be associated with a lower heart rate and improved laboratory hydration parameters during or after the ride. Methods: 14 client owned horses entered in a 45 km ride in extreme heat and terrain were randomly assigned to receive IV fluids (IVF) or no IV fluids (NIV) the day before the ride. Blood samples and physical examination findings were collected at 6 ti...
Musculoskeletal examination of the hind limb of the horse.
Journal of the American Veterinary Medical Association    August 7, 2026   1 doi: 10.2460/javma.26.03.0234
Kamm JL, Odegaard J, Mogannam B.The intention of this tutorial video is to illustrate the methods of examining the hind limb and back of a horse in order to identify abnormalities that may be associated with lameness or disease. Unassigned: An 18-year-old quarter horse stallion was used for examination. Unassigned: The horse was examined for abnormalities using physical examination. Unassigned: The examination of the hind limb and epaxial region of the horse was successfully completed. Unassigned: The techniques described are required to identify abnormalities in the equine hind limb and can be utilized during a lameness exa...
Detection of Cyclosporine in Horse Hair After Ocular Implant Administration.
Drug testing and analysis    August 7, 2026   doi: 10.1002/dta.70132
Lam IPY, So YM, Kwok WH, Yau W, Wong COL, Smalley SGR, Forbes BS, Chow DWY, Ho ENM.This study describes the detection and temporal distribution of cyclosporine in equine hair following ocular implant administration in a Thoroughbred gelding. Mane hair samples were collected at 172- and 217-day post-implantation and analysed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) after alkaline hydrolysis and liquid-liquid extraction. The method achieved an estimated limit of detection of 0.1 pg/mg. Cyclosporine was detected in hair at both sampling time points, with segmental analysis revealing distribution patterns consistent with systemic exposure and incorporation ...
Monitoring Estra-4,9-Diene-3,17-Dione Exposure in Equine Hair.
Drug testing and analysis    August 7, 2026   doi: 10.1002/dta.70128
Ip TKY, So YM, Kwok WH, Yuen SMS, Wong COL, Farrington AF, Bond AJ, Ho ENM.This study investigated the incorporation of estra-4,9-diene-3,17-dione (dienedione) and its metabolites into equine hair following exogenous administration and evaluates the potential application of hair analysis for long-term doping surveillance. Mane hair samples were collected from three Thoroughbred castrated horses before and after oral administration of dienedione and from untreated colts for comparison. Dienedione was detected in post-administration hair from all treated horses but was absent in corresponding pre-administration samples. Segmental distribution patterns indicated contrib...
Complications Following Nictitating Membrane Resection in Horses: 92 Eyes (2015-2024).
Veterinary ophthalmology    August 6, 2026   Volume 29, Issue 5 e70243 doi: 10.1111/vop.70243
Wu T, Stefanovski D, Scherrer NM.The goal of this retrospective study is to evaluate the complications following nictitating membrane resection in horses with the aim of providing valuable information on the risks of this surgical procedure. Methods: 83 horses (92 eyes). Methods: Medical records for 83 horses that underwent nictitating membrane resection in 92 eyes between February 2015 and June 2024 were reviewed. Horses were included if they had at least 1 month of follow-up data available. Owners were contacted via telephone or email questionnaire to obtain follow-up information. Complications were recorded only when pre...
Evaluation of sequential serum amyloid A measurements for the prediction of sepsis and survival in critically ill neonatal foals.
Journal of veterinary internal medicine    August 6, 2026   Volume 40, Issue 4 aalag155 doi: 10.1093/jvimsj/aalag155
de Bruijn E, Pas ML, Castelain D, Dufourni A, Paulussen E, Pardon B.Single measurements of serum amyloid A (SAA) concentration at hospital admission has limited sensitivity for predicting sepsis and death. Objective: To determine whether differences in SAA during the first 2 days of hospitalization could predict sepsis and death in critically ill foals. Methods: One hundred twenty-seven critically ill neonatal foals, <14 days of age. Methods: Prospective cohort study. SAA was measured at hospital admission and on day 2 of hospitalization using a validated point-of-care test. Logistic regression was conducted to evaluate the predictive value of individual S...
Eight Weeks of 448 kHz Radiofrequency Therapy Increases Multifidus Muscle Cross-Sectional Area and Modulates Thoracolumbar Range of Motion in Horses with Chronic Back Pain.
Animals : an open access journal from MDPI    August 6, 2026   Volume 16, Issue 15 2437 doi: 10.3390/ani16152437
Beaussart M, Perrin R, Marunova E, Moraine F, Fourteau D, Blake R.We aimed to investigate the effects of an 8-week 448 kHz radiofrequency (RF) on multifidus cross-sectional area (CSA) and thoracolumbar differential range of motion (ROM). Eight Thoroughbred horseball horses received four RF treatments (T9-L6) at 2-week intervals. Multifidus CSA (T10-L5) and differential spinal ROM between the withers (W), T13, T18, L3 and sacrum (S) were measured before treatment, immediately after the first session, 24 h after the first session, and at 8 weeks (15 days after the last session). Linear mixed models with Tukey post hoc comparisons were used. Significant effects...
Four Haylages, One Metabonome: Defining Diet Driven Metabolic Shifts in Ponies.
Journal of animal physiology and animal nutrition    August 6, 2026   doi: 10.1111/jpn.70099
Moore-Colyer M, Harris P, Daniels S.Haylage is widely fed to all categories of stabled horses across Europe and New Zealand. Haylage can vary from high energy nutrient dense forage to low energy highly fibrous fodder, yet little is known about the impact different haylages have on metabolism in horses. This study provides the first direct comparison of feeding four different haylages: early cut (Lolium multiflorum), later cut (Lolium perenne) rye grass (R1 and R2); early and late cut meadow grass (M1 and M2), on urinary and faecal metabonomics, in ponies at maintenance. Using replicated Latin Square design, eight individually ho...
Sleep architecture and lying behavior in horses across age groups and two housing systems: an overnight non-invasive EEG study.
Frontiers in veterinary science    August 6, 2026   Volume 13 1898580 doi: 10.3389/fvets.2026.1898580
Zimmer L, Schramel JP, Lyrakis M, Trachsel DS, Auer U, Leschnik M, Macho-Maschler S, Hotz M, Wahl H, Brunner S, Palme R, Cavalleri JV.Sleep is a crucial factor for the well-being of horses, yet assessing equine sleep in common housing conditions remains challenging. This study investigated the effects of changes in horses' immediate environment and the influence of age on their sleep and resting behavior using a novel, non-invasive electroencephalography (EEG) mask. Ten horses from the teaching herd at the University of Veterinary Medicine Vienna were observed over four consecutive nights in two different housing systems (a large communal stable vs. two separate, adjacent individual stalls). Data collection included EEG reco...
Clinical outcomes of a novel flowable calcium silicate cement in equine endodontic treatment.
Equine veterinary journal    August 5, 2026   doi: 10.1002/evj.70299
Jackson K, Faulkner J, Staszyk C, Ha W, Quintrell E, Kelty E.Orthograde endodontic treatment of equine cheek teeth is performed infrequently with variable success rates of obturation with calcium hydroxide paste (CHP). A novel flowable calcium silicate cement (eCSC) formulated for use as an obturation material in equine teeth has demonstrated acceptable canal filling volumes and evidence of dentinal tubule penetration. However, clinical outcomes of eCSC-obturated equine teeth have not been reported. Objective: To report the clinical outcomes of orthograde endodontic treatment using eCSC. Methods: Retrospective case series. Methods: Horses that underwent...
Short-term effects of pulsed electromagnetic field therapy on subjective flexion-associated lameness responses and circulating cytokines in horses with distal tarsal osteoarthritis.
Journal of equine veterinary science    August 5, 2026   106106 doi: 10.1016/j.jevs.2026.106106
Wilson I, Kiger K, Reynolds S, Justice M, Kapadia C, Coleman SJ, Crook RA, Fedorka CE.Pulsed electromagnetic field (PEMF) therapy is commonly used in equine sports medicine for its proposed anti-inflammatory effects; however, limited controlled studies have evaluated its physiologic effects in horses. Objective: The objective of this study was to investigate the effects of PEMF therapy on flexion-induced lameness and circulating cytokines in horses with radiographic evidence of distal tarsal osteoarthritis. Methods: Six mares were enrolled in a repeated-measures crossover design in which each horse served as its own control. Horses were evaluated at baseline (sham PEMF) and at ...
Russell’s viper envenomation in a 9-month pregnant mare saved with high-dose antivenom: a first-in-world case report.
Transactions of the Royal Society of Tropical Medicine and Hygiene    August 4, 2026   trag076 doi: 10.1093/trstmh/trag076
Raut SD, Khambatta P, Raut P, Raut S.Snakebite during pregnancy is an uncommon but potentially catastrophic event, with maternal and foetal outcomes closely related to the severity of envenomation. While snakebite in pregnant women has been sporadically reported and is known to be associated with significant obstetrical complications, envenomation in animals, particularly in pregnant horses, is exceedingly rare. Only a few isolated cases of snakebite in horses have been documented, and to the best of our knowledge, snakebite in a pregnant mare has not been previously reported in the medical or veterinary literature. Russell's vip...
Cryopreserved umbilical allograft (equicenta® CTM) improves clinical outcomes compared with clinician-selected standard of care in performance horses: a pragmatic prospective controlled trial.
Frontiers in veterinary science    August 4, 2026   Volume 13 1833933 doi: 10.3389/fvets.2026.1833933
Bertone AL, Davern AJ, Sutter WW, Mesch H, Beinlich C, Smith A, Ramstrom C, White S, Dubynsky B, Cantrell K, Hay BP, Davis W, Mazzarelli L.This multicenter, prospective, controlled clinical study and client survey evaluated the safety and effectiveness of an equine umbilical tissue suspension (equicenta® CTM; eCTM, 2:1) compared with clinician-selected standard of care (SOC) for treating lame performance horses. Unassigned: This pragmatic, real-world, open-label study enrolled horses diagnosed with appendicular musculoskeletal conditions affecting the joints, tendons, or ligaments under owner consent and an intention-to-treat design with an optional crossover after no improvement at 12 weeks and per-protocol analyses at 26 ...
Rethinking Equine Cystitis: Evidence from Four Atypical Clinical Presentations.
Life (Basel, Switzerland)    August 4, 2026   Volume 16, Issue 8 1285 doi: 10.3390/life16081285
Biazik A, Sobuś M, Henklewski R, Wieteska M, Kordowitzki P.In this case series, four equines were diagnosed with cystitis, resulting in divergent clinical outcomes. Three animals achieved complete clinical resolution without recurrence, whereas one required euthanasia due to progressive clinical deterioration. All diagnoses were established through a dual-modality investigative protocol comprising cystoscopic evaluation and histopathological examination of bladder mucosal biopsies. The cohort exhibited considerable etiological heterogeneity. One case was classified as chronic idiopathic cystitis, while another was attributed to an opportunistic bacter...
Comparison of xylazine-ketamine-guaifenesin and xylazine-tiletamine-zolazepam protocols for constant rate infusion anesthesia in horses undergoing field castration.
Journal of equine veterinary science    August 3, 2026   106109 doi: 10.1016/j.jevs.2026.106109
Maneephan P, Thepparat K, Suwanekkasit B, Limrodpai J, Sangbunjong A, Karkkaew P, Chantong B, Vinijkumthorn R.The common use of "triple drip" (xylazine, ketamine, and guaifenesin; XKG) is a popular protocol for constant rate infusion (CRI) in equine practice. However, due to restrictions on ketamine and guaifenesin in many countries, tiletamine-zolazepam (TZ) could serve as an alternative. To date, there have been limited studies evaluating the use of xylazine in combination with TZ (XTZ) administered via CRI to maintain surgical anesthesia in equine field practice. Objective: To compare the effectiveness and safety of XTZ infusion with the classical XKG protocol for field anesthesia. Methods: Twelve ...
Health assessment of Tokara horses on Nakanoshima island: potential chronic hepatic dysfunction induced by Leopard plant (Farfugium japonicum) ingestion.
The Journal of veterinary medical science    August 3, 2026   doi: 10.1292/jvms.26-0275
Yamashita N, Yoshihara T, Hatazoe T, Misumi K, Hobo S.We investigated the health of Tokara horses (n=34) on Nakanoshima as part of conservation efforts for this breed. Although the horses were clinically healthy, elevated white blood cell count, neutrophil count and gamma-glutamyl transferase (GGT) levels were observed, leading to suspicion of chronic hepatic dysfunction and infectious disease. A survey revealed that the caretakers had been feeding the horses Leopard plant, which contains toxic pyrrolizidine alkaloids (PAs). The abnormal GGT levels observed in these horses may suggest the possibility of chronic PA poisoning resulting from the con...
Cold Atmospheric Plasma-Aerosol Treatment of Equine Antibiotic-Resistant Wound Infection: A Preliminary Case Series.
Animals : an open access journal from MDPI    August 3, 2026   Volume 16, Issue 15 2380 doi: 10.3390/ani16152380
Kurras S, Conze TM, Obermann S, Fuchs R, Tischendorf T, Knottenbelt DC, Koene M.Wound infections are common sequelae of wound treatment in horses. Secondary bacterial colonization with antimicrobial resistant microorganisms is of particular concern and is of crucial importance regarding the "One Health Concept". Due to frequent antimicrobial resistance (AMR), conventional treatments often involve determining resistance and sensitivity using time-consuming antibiograms. Infections with multi-resistant pathogens are especially challenging. This case series presents studies of four horses evaluating the efficacy of Cold Atmospheric Plasma-Aerosol (CAP-A) as a standalone trea...
Advanced 3D Horse Reconstruction: Integrating Image-to-3D Modelling and Non-Rigid Registration for On-Barn Body Measurements.
Animals : an open access journal from MDPI    August 3, 2026   Volume 16, Issue 15 2397 doi: 10.3390/ani16152397
Yuan X, Wang S, Zhu Q, Wang Y, Ruchay A, Pezzuolo A, Wang Q, Li J, Guo H.Precision livestock farming (PLF) relies on high-precision three-dimensional (3D) horse reconstruction and automatic body measurement to support refined breeding management and health surveillance. However, data collection is restricted by building environment noise and hardware layout constraints; complex equine body shapes and large individual variations induce local geometric distortions in reconstructed models, limiting field deployment. Drawing on generative 3D reconstruction, this study develops the first image-to-3D pipeline that leverages three consumer depth cameras to reconstruct hig...
Core decompression augmented with bone marrow aspirate concentrate for refractory distal sesamoid bone pathology in horses: A retrospective clinical study.
Veterinary surgery : VS    August 1, 2026   doi: 10.1111/vsu.70139
Maleas G, Mageed M, Hargitaiova K.To determine short- and long-term outcomes of core decompression combined with autologous bone marrow aspirate concentrate (BMAC) in treating moderate-to-severe refractory distal sesamoid bone (DSB) trabecular pathology in horses. Methods: Retrospective observational study. Methods: A total of 21 client-owned Warmblood horses with DSB pathology unresponsive to conservative management. Methods: Preoperative diagnosis included lameness localization by diagnostic analgesia and magnetic resonance imaging (MRI) confirmation of DSB trabecular pathology. Horses underwent arthroscopic core decompressi...
Intrauterine ozone therapy reduces bacterial load in mares with mixed bacterial endometritis: a longitudinal study.
Veterinary research communications    July 31, 2026   Volume 50, Issue 5 497 doi: 10.1007/s11259-026-11438-3
Campos DG, Araujo RR, Feltrin SR, Botelho JHV, Cargnelutti JF, Portela VM, Dos Santos Amaral C, Antoniazzi AQ.Mixed bacterial endometritis poses a therapeutic challenge in mares due to the coexistence of multiple pathogens with divergent antimicrobial susceptibility profiles. This study evaluated the effects of intrauterine ozone insufflation on uterine bacterial load and endometrial inflammatory response in mares with naturally acquired mixed bacterial endometritis. Fifteen mares with mixed bacterial infection were allocated to two treatment groups: a pathological control group receiving pure medical oxygen insufflation (PC; n = 6) and an ozone-treated group receiving 42 µg/mL ozone for three c...
Seasonal modulation of platelet indices in mares.
Chronobiology international    July 31, 2026   1-12 doi: 10.1080/07420528.2026.2710242
Satué K, La Fauci D, Colomer-Selva R, Cravana C, Fazio E.Platelet indices provide valuable information on platelet activation, heterogeneity, and production kinetics, yet their physiological variability remains poorly characterized in horses. Although seasonal changes in platelet count have been described, the seasonal modulation of derived platelet indices in mares remains poorly understood. The aim of this study was to evaluate the seasonal variation of platelet count and derived platelet indices in clinically healthy mares from the Valencia region (Spain), and to assess their interrelationships. Forty clinically healthy Spanish Purebred mares (6-...
Technical note on cervical epidural catheterization in two adult horses: Injectate distribution and epidural space effects.
Veterinary surgery : VS    July 30, 2026   doi: 10.1111/vsu.70140
O'Scanaill O, Moorman VJ, Perlini M, Reed RA.To determine the caudalmost extent of diffusion of contrast media administered through a cervical epidural catheter (CEC) and to describe pathologic changes associated with maintaining an indwelling CEC for up to 17 days. Methods: Pilot study. Methods: Two mature horses. Methods: CECs were placed under ultrasound guidance in two horses. Both horses were injected with 5 mL 50% Iohexol contrast solution, followed by radiographs of catheter insertion site to confirm placement. A total volume of 15 mL contrast solution was injected in 5 mL aliquots up to 25 min post-initial injection. La...
Evaluation of Microvascular Flow Imaging and Power Doppler Ultrasonography in an Equine Model of Induced Superficial Digital Flexor Tendonitis. Garcia-Collao MR, Ortved K, Stefanovski D, Christensen JL, Underwood C.Superficial digital flexor tendon (SDFT) injuries are common in athletic horses and are associated with prolonged healing and high reinjury rates. Conventional ultrasonography provides structural information but limited physiologic assessment. This study compared microvascular imaging (MVI) and Power Doppler (PD) for evaluating vascular changes in a collagenase-induced equine SDFT injury model and assessed the effect of scanning technique on vascular signal detection. Eight adult Thoroughbred horses underwent bilateral collagenase-induced SDFT injury, with one forelimb randomly assigned to int...
Approaches to Thoroughbred Horse Identification in Diverse Sample Types Using Multiplexed SNP-PCR Sequencing Panels.
Animal genetics    July 29, 2026   Volume 57, Issue 4 e70170 doi: 10.1002/age.70170
Maniego J, Harding C, Hincks P, Habershon-Butcher J, Ryder E.The ability to determine the identity of equine samples would be highly advantageous in cases of ambiguous sample source, as individual-specific controls for gene editing detection, or forensic examination of suspect biological materials in potential doping cases. To this end, a SNP-PCR sequencing-based panel comprising 93 markers in one reaction was designed and investigated for use in Thoroughbred horses. Marker amplification performance and discriminating power were calculated against a population survey of 264 Thoroughbred whole blood samples from routine doping testing. The sensitivity of...
Favorable survival of horses with guttural pouch mycosis following hospital-based treatment.
Journal of the American Veterinary Medical Association    July 29, 2026   1-6 doi: 10.2460/javma.26.04.0248
Phillips NAI, McOnie RC, Delvescovo B, Radcliffe R, Ducharme NG, Hackett ES.To report the clinical outcomes and survival time in horses undergoing treatment of guttural pouch mycosis. Unassigned: Client-owned horses with guttural pouch mycosis admitted between 2005 and 2024 for evaluation and treatment were identified by medical record search. Signalment, disease history, and surgical and treatment details were recorded. Owners were contacted for follow-up information. Unassigned: 41 horses with guttural pouch mycosis were identified, of which 28 had epistaxis or a history of epistaxis on presentation. Thirty-five horses underwent surgical treatment, and the procedure...
A postmortem grading system for articular cartilage loss of the dorsoproximal aspect of the proximal phalanx of Thoroughbred racehorses. Gibson MJ, Dittmer KE, Legg KA, Wehrle-Martinez AS, Beggan CP, Sommerville GO, Rogers CW.The metacarpophalangeal and metatarsophalangeal joints in Thoroughbred racehorses are common injury sites, given their high range of motion and compression during galloping. In New Zealand, the proximal phalanx (P1) is a common site for race-day fracture, but the lesions of this bone have not been described. Therefore, we created a scoring system to describe cartilage on the dorsoproximal aspect of P1 in New Zealand Thoroughbred racehorses. We collected 102 P1s from racehorses submitted for postmortem examination. Horses were categorized into 2 cohorts: 1) fracture (18 horses euthanized becaus...
Equine nuclear medicine: Current state of play.
Seminars in nuclear medicine    July 29, 2026   S0001-2998(26)00143-1 doi: 10.1053/j.semnuclmed.2026.07.004
Tually P, Becker S, Currie GM.Equine nuclear medicine provides functional information on bone turnover, perfusion, inflammation and tracer biodistribution. Its role has evolved from planar scintigraphy toward SPECT, PET and quantitative imaging. This review synthesised the historical foundations and contemporary state of equine nuclear medicine, with emphasis on racehorse and performance-horse applications. Methods: A PRISMA-aligned systematic narrative review and evidence map were undertaken. MEDLINE via PubMed, Web of Science Core Collection and SciQuest were searched, supplemented by reference-list screening, forward ci...
Effect of neonatal rib fracture repair on racing and sales performance in Thoroughbreds.
Equine veterinary journal    July 28, 2026   doi: 10.1002/evj.70218
Young LM, Courtney ER, Freeland RB.The racing outcome of horses that have undergone surgical repair of neonatal rib fractures is not well documented. Objective: To evaluate the impact of surgical repair of neonatal rib fractures on subsequent sales and racing performance in Thoroughbreds. Methods: Retrospective cohort study. Methods: Medical records of neonatal Thoroughbreds that underwent surgical repair of rib fractures at a referral hospital between 2014 and 2025 were reviewed. Sales and racing data were obtained from publicly available databases. Outcomes assessed included sale price at weanling and yearling sales, total ca...
Risk factors for horse falls in British jump racing (2010-2023).
Equine veterinary journal    July 27, 2026   doi: 10.1002/evj.70215
Allen SE, Taylor S, Given J, Verheyen KLP.Horse falls are an important safety and welfare concern in jump racing, as they are associated with an increased risk of equine fatality and injury, as well as jockey injury. Objective: To identify risk factors for horse falls in British jump racing. Methods: Retrospective cohort. Methods: All jump race starts made on British racecourses between January 2010 and April 2023 were considered. Available horse, race, racecourse, trainer and jockey data were collated and combined with faller data recorded in official databases. Horses that were 'brought down' by another horse were not considered a f...