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Topic:Equine Medicine

Equine Medicine encompasses the study and application of medical practices specifically related to the health and well-being of horses. This field involves the diagnosis, treatment, and prevention of diseases and disorders affecting equine species. It covers a wide range of topics, including internal medicine, surgery, reproduction, and pharmacology. Research in equine medicine often focuses on understanding the physiological and pathological processes unique to horses, as well as developing effective therapeutic interventions. This page aggregates peer-reviewed research studies and scholarly articles that explore various aspects of equine medicine, providing insights into the latest advancements and methodologies in the care and management of horse health.
Pelvic axial rotation in hindlimb lame horses changes after diagnostic analgesia.
Equine veterinary journal    August 10, 2026   doi: 10.1002/evj.70300
Hernlund E, Engell MT, Persson-Sjödin E, Rhodin M, Haubro-Andersen P, Byström A.Visual assessment of mild to moderate hindlimb lameness has low sensitivity and specificity, potentially leading to flawed diagnostic procedures. Pelvic axial rotation (roll) makes the assessment more complex but is also a potential source of information. Objective: To describe pelvic roll patterns in horses with unilateral hindlimb lameness before and after diagnostic analgesia. Methods: Retrospective study. Methods: Optical motion capture data from 20 horses with unilateral hindlimb lameness before and after successful local analgesia (assessed visually and objectively) were retrospectively ...
Comparison of Fogarty and Vollmar thrombectomy for chronic jugular thrombosis in horses.
Equine veterinary journal    August 9, 2026   doi: 10.1002/evj.70305
Pizzigatti D, Alonso JM, Cerqueira NF, Rosa VBB, Rafael LA, Rodrigues CA, Watanabe MJ, Alves ALG, Hussni CA.Chronic jugular vein thrombosis may result in persistent venous obstruction and impaired head drainage. Although surgical thrombectomy is performed in selected cases, experimental comparisons between mechanical techniques for chronic thrombus removal in horses are lacking. Objective: To compare Fogarty catheter thrombectomy alone with a combined Vollmar ring-Fogarty technique for restoration and maintenance of luminal patency in experimentally induced chronic jugular thrombosis. Methods: Randomised in vivo study. Methods: Chronic right jugular thrombosis was induced in 10 healthy adult horses....
Whole-genome characterization and phylogenetic analysis of Equine Rotavirus A isolated from Jeju Island, Korea.
Journal of veterinary science    August 9, 2026   Volume 27, Issue 4 e40 doi: 10.4142/jvs.25333
Pham TT, Lee DH, Ko EJ.Equine Rotavirus A (ERVA) is a major cause of acute diarrhea in neonatal foals, leading to significant economic losses. Genetic variation and global transmission complicate disease control efforts. Objective: To analyze the complete genome of an ERVA strain from Jeju Island, Korea, and assess its genetic and phylogenetic relationships with global ERVA strains. Methods: Twenty-five fecal and swab samples were collected from diarrheic horses in Jeju during spring and summer 2025. Samples were screened using antigen testing and RT-PCR. One PCR-positive, antigen-test-positive sample was selected f...
Horse Anatomy and Art: Carlo Ruini.
Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft    August 8, 2026   153351 doi: 10.1016/j.aanat.2026.153351
Merighi A.Carlo Ruini's Dell'Anotomia et dell'infirmità del cavallo (1598) is widely regarded as the first scientific treatise on veterinary anatomy. This paper reviews the historical circumstances of its composition and printing history, the structure and scientific content of its five anatomical books, the long-standing controversy over Ruini's authorship - including the plagiarisms it subsequently suffered - and the disputed attribution of its woodcut illustrations to artists such as Leonardo da Vinci, Titian and Agostino Carracci. Ruini's description of the pulmonary circulation is situated within ...
Leptomeningeal dissemination of a poorly differentiated carcinoma involving the trigeminal ganglion in a horse: a case report.
Journal of equine veterinary science    August 8, 2026   106123 doi: 10.1016/j.jevs.2026.106123
Rocha CSV, Ferreira CS, Jesus CVA, Silveira MDL, Gomes KMC, Júnior VAS, Gobbi FP, Fonseca SR, Oliveira AAF.Neoplastic conditions involving cranial nerves are uncommon in horses and represent a significant diagnostic challenge. Leptomeningeal dissemination is a recognized mechanism of tumor progression in aggressive neoplasms but is rarely reported in this species. A 15-year-old mixed-breed horse with a history of periocular squamous cell carcinoma treated by enucleation three years earlier developed progressive neurological signs. Initial differential diagnoses included metastatic neoplasia and equine protozoal myeloencephalitis. Due to rapid neurological deterioration, euthanasia and necropsy were...
The effect of intravenous fluids administered prior to competition: A randomized clinical.
Journal of equine veterinary science    August 8, 2026   106121 doi: 10.1016/j.jevs.2026.106121
Weintraub L, Fielding CL, Carli I, Greene-Dittz G.Administration of intravenous fluids prior to competition is common at major equestrian competitions, yet few studies have evaluated the benefits of this practice. Objective: The hypothesis was that pre-ride intravenous fluid therapy would be associated with a lower heart rate and improved laboratory hydration parameters during or after the ride. Methods: 14 client owned horses entered in a 45 km ride in extreme heat and terrain were randomly assigned to receive IV fluids (IVF) or no IV fluids (NIV) the day before the ride. Blood samples and physical examination findings were collected at 6 ti...
Musculoskeletal examination of the hind limb of the horse.
Journal of the American Veterinary Medical Association    August 7, 2026   1 doi: 10.2460/javma.26.03.0234
Kamm JL, Odegaard J, Mogannam B.The intention of this tutorial video is to illustrate the methods of examining the hind limb and back of a horse in order to identify abnormalities that may be associated with lameness or disease. Unassigned: An 18-year-old quarter horse stallion was used for examination. Unassigned: The horse was examined for abnormalities using physical examination. Unassigned: The examination of the hind limb and epaxial region of the horse was successfully completed. Unassigned: The techniques described are required to identify abnormalities in the equine hind limb and can be utilized during a lameness exa...
Detection of Cyclosporine in Horse Hair After Ocular Implant Administration.
Drug testing and analysis    August 7, 2026   doi: 10.1002/dta.70132
Lam IPY, So YM, Kwok WH, Yau W, Wong COL, Smalley SGR, Forbes BS, Chow DWY, Ho ENM.This study describes the detection and temporal distribution of cyclosporine in equine hair following ocular implant administration in a Thoroughbred gelding. Mane hair samples were collected at 172- and 217-day post-implantation and analysed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) after alkaline hydrolysis and liquid-liquid extraction. The method achieved an estimated limit of detection of 0.1 pg/mg. Cyclosporine was detected in hair at both sampling time points, with segmental analysis revealing distribution patterns consistent with systemic exposure and incorporation ...
Monitoring Estra-4,9-Diene-3,17-Dione Exposure in Equine Hair.
Drug testing and analysis    August 7, 2026   doi: 10.1002/dta.70128
Ip TKY, So YM, Kwok WH, Yuen SMS, Wong COL, Farrington AF, Bond AJ, Ho ENM.This study investigated the incorporation of estra-4,9-diene-3,17-dione (dienedione) and its metabolites into equine hair following exogenous administration and evaluates the potential application of hair analysis for long-term doping surveillance. Mane hair samples were collected from three Thoroughbred castrated horses before and after oral administration of dienedione and from untreated colts for comparison. Dienedione was detected in post-administration hair from all treated horses but was absent in corresponding pre-administration samples. Segmental distribution patterns indicated contrib...
Complications Following Nictitating Membrane Resection in Horses: 92 Eyes (2015-2024).
Veterinary ophthalmology    August 6, 2026   Volume 29, Issue 5 e70243 doi: 10.1111/vop.70243
Wu T, Stefanovski D, Scherrer NM.The goal of this retrospective study is to evaluate the complications following nictitating membrane resection in horses with the aim of providing valuable information on the risks of this surgical procedure. Methods: 83 horses (92 eyes). Methods: Medical records for 83 horses that underwent nictitating membrane resection in 92 eyes between February 2015 and June 2024 were reviewed. Horses were included if they had at least 1 month of follow-up data available. Owners were contacted via telephone or email questionnaire to obtain follow-up information. Complications were recorded only when pre...
Evaluation of sequential serum amyloid A measurements for the prediction of sepsis and survival in critically ill neonatal foals.
Journal of veterinary internal medicine    August 6, 2026   Volume 40, Issue 4 aalag155 doi: 10.1093/jvimsj/aalag155
de Bruijn E, Pas ML, Castelain D, Dufourni A, Paulussen E, Pardon B.Single measurements of serum amyloid A (SAA) concentration at hospital admission has limited sensitivity for predicting sepsis and death. Objective: To determine whether differences in SAA during the first 2 days of hospitalization could predict sepsis and death in critically ill foals. Methods: One hundred twenty-seven critically ill neonatal foals, <14 days of age. Methods: Prospective cohort study. SAA was measured at hospital admission and on day 2 of hospitalization using a validated point-of-care test. Logistic regression was conducted to evaluate the predictive value of individual S...
Eight Weeks of 448 kHz Radiofrequency Therapy Increases Multifidus Muscle Cross-Sectional Area and Modulates Thoracolumbar Range of Motion in Horses with Chronic Back Pain.
Animals : an open access journal from MDPI    August 6, 2026   Volume 16, Issue 15 2437 doi: 10.3390/ani16152437
Beaussart M, Perrin R, Marunova E, Moraine F, Fourteau D, Blake R.We aimed to investigate the effects of an 8-week 448 kHz radiofrequency (RF) on multifidus cross-sectional area (CSA) and thoracolumbar differential range of motion (ROM). Eight Thoroughbred horseball horses received four RF treatments (T9-L6) at 2-week intervals. Multifidus CSA (T10-L5) and differential spinal ROM between the withers (W), T13, T18, L3 and sacrum (S) were measured before treatment, immediately after the first session, 24 h after the first session, and at 8 weeks (15 days after the last session). Linear mixed models with Tukey post hoc comparisons were used. Significant effects...
Four Haylages, One Metabonome: Defining Diet Driven Metabolic Shifts in Ponies.
Journal of animal physiology and animal nutrition    August 6, 2026   doi: 10.1111/jpn.70099
Moore-Colyer M, Harris P, Daniels S.Haylage is widely fed to all categories of stabled horses across Europe and New Zealand. Haylage can vary from high energy nutrient dense forage to low energy highly fibrous fodder, yet little is known about the impact different haylages have on metabolism in horses. This study provides the first direct comparison of feeding four different haylages: early cut (Lolium multiflorum), later cut (Lolium perenne) rye grass (R1 and R2); early and late cut meadow grass (M1 and M2), on urinary and faecal metabonomics, in ponies at maintenance. Using replicated Latin Square design, eight individually ho...
Sleep architecture and lying behavior in horses across age groups and two housing systems: an overnight non-invasive EEG study.
Frontiers in veterinary science    August 6, 2026   Volume 13 1898580 doi: 10.3389/fvets.2026.1898580
Zimmer L, Schramel JP, Lyrakis M, Trachsel DS, Auer U, Leschnik M, Macho-Maschler S, Hotz M, Wahl H, Brunner S, Palme R, Cavalleri JV.Sleep is a crucial factor for the well-being of horses, yet assessing equine sleep in common housing conditions remains challenging. This study investigated the effects of changes in horses' immediate environment and the influence of age on their sleep and resting behavior using a novel, non-invasive electroencephalography (EEG) mask. Ten horses from the teaching herd at the University of Veterinary Medicine Vienna were observed over four consecutive nights in two different housing systems (a large communal stable vs. two separate, adjacent individual stalls). Data collection included EEG reco...
Clinical outcomes of a novel flowable calcium silicate cement in equine endodontic treatment.
Equine veterinary journal    August 5, 2026   doi: 10.1002/evj.70299
Jackson K, Faulkner J, Staszyk C, Ha W, Quintrell E, Kelty E.Orthograde endodontic treatment of equine cheek teeth is performed infrequently with variable success rates of obturation with calcium hydroxide paste (CHP). A novel flowable calcium silicate cement (eCSC) formulated for use as an obturation material in equine teeth has demonstrated acceptable canal filling volumes and evidence of dentinal tubule penetration. However, clinical outcomes of eCSC-obturated equine teeth have not been reported. Objective: To report the clinical outcomes of orthograde endodontic treatment using eCSC. Methods: Retrospective case series. Methods: Horses that underwent...
Short-term effects of pulsed electromagnetic field therapy on subjective flexion-associated lameness responses and circulating cytokines in horses with distal tarsal osteoarthritis.
Journal of equine veterinary science    August 5, 2026   106106 doi: 10.1016/j.jevs.2026.106106
Wilson I, Kiger K, Reynolds S, Justice M, Kapadia C, Coleman SJ, Crook RA, Fedorka CE.Pulsed electromagnetic field (PEMF) therapy is commonly used in equine sports medicine for its proposed anti-inflammatory effects; however, limited controlled studies have evaluated its physiologic effects in horses. Objective: The objective of this study was to investigate the effects of PEMF therapy on flexion-induced lameness and circulating cytokines in horses with radiographic evidence of distal tarsal osteoarthritis. Methods: Six mares were enrolled in a repeated-measures crossover design in which each horse served as its own control. Horses were evaluated at baseline (sham PEMF) and at ...
Russell’s viper envenomation in a 9-month pregnant mare saved with high-dose antivenom: a first-in-world case report.
Transactions of the Royal Society of Tropical Medicine and Hygiene    August 4, 2026   trag076 doi: 10.1093/trstmh/trag076
Raut SD, Khambatta P, Raut P, Raut S.Snakebite during pregnancy is an uncommon but potentially catastrophic event, with maternal and foetal outcomes closely related to the severity of envenomation. While snakebite in pregnant women has been sporadically reported and is known to be associated with significant obstetrical complications, envenomation in animals, particularly in pregnant horses, is exceedingly rare. Only a few isolated cases of snakebite in horses have been documented, and to the best of our knowledge, snakebite in a pregnant mare has not been previously reported in the medical or veterinary literature. Russell's vip...
Cryopreserved umbilical allograft (equicenta® CTM) improves clinical outcomes compared with clinician-selected standard of care in performance horses: a pragmatic prospective controlled trial.
Frontiers in veterinary science    August 4, 2026   Volume 13 1833933 doi: 10.3389/fvets.2026.1833933
Bertone AL, Davern AJ, Sutter WW, Mesch H, Beinlich C, Smith A, Ramstrom C, White S, Dubynsky B, Cantrell K, Hay BP, Davis W, Mazzarelli L.This multicenter, prospective, controlled clinical study and client survey evaluated the safety and effectiveness of an equine umbilical tissue suspension (equicenta® CTM; eCTM, 2:1) compared with clinician-selected standard of care (SOC) for treating lame performance horses. Unassigned: This pragmatic, real-world, open-label study enrolled horses diagnosed with appendicular musculoskeletal conditions affecting the joints, tendons, or ligaments under owner consent and an intention-to-treat design with an optional crossover after no improvement at 12 weeks and per-protocol analyses at 26 ...
Rethinking Equine Cystitis: Evidence from Four Atypical Clinical Presentations.
Life (Basel, Switzerland)    August 4, 2026   Volume 16, Issue 8 1285 doi: 10.3390/life16081285
Biazik A, Sobuś M, Henklewski R, Wieteska M, Kordowitzki P.In this case series, four equines were diagnosed with cystitis, resulting in divergent clinical outcomes. Three animals achieved complete clinical resolution without recurrence, whereas one required euthanasia due to progressive clinical deterioration. All diagnoses were established through a dual-modality investigative protocol comprising cystoscopic evaluation and histopathological examination of bladder mucosal biopsies. The cohort exhibited considerable etiological heterogeneity. One case was classified as chronic idiopathic cystitis, while another was attributed to an opportunistic bacter...
Comparison of xylazine-ketamine-guaifenesin and xylazine-tiletamine-zolazepam protocols for constant rate infusion anesthesia in horses undergoing field castration.
Journal of equine veterinary science    August 3, 2026   106109 doi: 10.1016/j.jevs.2026.106109
Maneephan P, Thepparat K, Suwanekkasit B, Limrodpai J, Sangbunjong A, Karkkaew P, Chantong B, Vinijkumthorn R.The common use of "triple drip" (xylazine, ketamine, and guaifenesin; XKG) is a popular protocol for constant rate infusion (CRI) in equine practice. However, due to restrictions on ketamine and guaifenesin in many countries, tiletamine-zolazepam (TZ) could serve as an alternative. To date, there have been limited studies evaluating the use of xylazine in combination with TZ (XTZ) administered via CRI to maintain surgical anesthesia in equine field practice. Objective: To compare the effectiveness and safety of XTZ infusion with the classical XKG protocol for field anesthesia. Methods: Twelve ...
Health assessment of Tokara horses on Nakanoshima island: potential chronic hepatic dysfunction induced by Leopard plant (Farfugium japonicum) ingestion.
The Journal of veterinary medical science    August 3, 2026   doi: 10.1292/jvms.26-0275
Yamashita N, Yoshihara T, Hatazoe T, Misumi K, Hobo S.We investigated the health of Tokara horses (n=34) on Nakanoshima as part of conservation efforts for this breed. Although the horses were clinically healthy, elevated white blood cell count, neutrophil count and gamma-glutamyl transferase (GGT) levels were observed, leading to suspicion of chronic hepatic dysfunction and infectious disease. A survey revealed that the caretakers had been feeding the horses Leopard plant, which contains toxic pyrrolizidine alkaloids (PAs). The abnormal GGT levels observed in these horses may suggest the possibility of chronic PA poisoning resulting from the con...
Cold Atmospheric Plasma-Aerosol Treatment of Equine Antibiotic-Resistant Wound Infection: A Preliminary Case Series.
Animals : an open access journal from MDPI    August 3, 2026   Volume 16, Issue 15 2380 doi: 10.3390/ani16152380
Kurras S, Conze TM, Obermann S, Fuchs R, Tischendorf T, Knottenbelt DC, Koene M.Wound infections are common sequelae of wound treatment in horses. Secondary bacterial colonization with antimicrobial resistant microorganisms is of particular concern and is of crucial importance regarding the "One Health Concept". Due to frequent antimicrobial resistance (AMR), conventional treatments often involve determining resistance and sensitivity using time-consuming antibiograms. Infections with multi-resistant pathogens are especially challenging. This case series presents studies of four horses evaluating the efficacy of Cold Atmospheric Plasma-Aerosol (CAP-A) as a standalone trea...
Advanced 3D Horse Reconstruction: Integrating Image-to-3D Modelling and Non-Rigid Registration for On-Barn Body Measurements.
Animals : an open access journal from MDPI    August 3, 2026   Volume 16, Issue 15 2397 doi: 10.3390/ani16152397
Yuan X, Wang S, Zhu Q, Wang Y, Ruchay A, Pezzuolo A, Wang Q, Li J, Guo H.Precision livestock farming (PLF) relies on high-precision three-dimensional (3D) horse reconstruction and automatic body measurement to support refined breeding management and health surveillance. However, data collection is restricted by building environment noise and hardware layout constraints; complex equine body shapes and large individual variations induce local geometric distortions in reconstructed models, limiting field deployment. Drawing on generative 3D reconstruction, this study develops the first image-to-3D pipeline that leverages three consumer depth cameras to reconstruct hig...
Core decompression augmented with bone marrow aspirate concentrate for refractory distal sesamoid bone pathology in horses: A retrospective clinical study.
Veterinary surgery : VS    August 1, 2026   doi: 10.1111/vsu.70139
Maleas G, Mageed M, Hargitaiova K.To determine short- and long-term outcomes of core decompression combined with autologous bone marrow aspirate concentrate (BMAC) in treating moderate-to-severe refractory distal sesamoid bone (DSB) trabecular pathology in horses. Methods: Retrospective observational study. Methods: A total of 21 client-owned Warmblood horses with DSB pathology unresponsive to conservative management. Methods: Preoperative diagnosis included lameness localization by diagnostic analgesia and magnetic resonance imaging (MRI) confirmation of DSB trabecular pathology. Horses underwent arthroscopic core decompressi...
Intrauterine ozone therapy reduces bacterial load in mares with mixed bacterial endometritis: a longitudinal study.
Veterinary research communications    July 31, 2026   Volume 50, Issue 5 497 doi: 10.1007/s11259-026-11438-3
Campos DG, Araujo RR, Feltrin SR, Botelho JHV, Cargnelutti JF, Portela VM, Dos Santos Amaral C, Antoniazzi AQ.Mixed bacterial endometritis poses a therapeutic challenge in mares due to the coexistence of multiple pathogens with divergent antimicrobial susceptibility profiles. This study evaluated the effects of intrauterine ozone insufflation on uterine bacterial load and endometrial inflammatory response in mares with naturally acquired mixed bacterial endometritis. Fifteen mares with mixed bacterial infection were allocated to two treatment groups: a pathological control group receiving pure medical oxygen insufflation (PC; n = 6) and an ozone-treated group receiving 42 µg/mL ozone for three c...
Seasonal modulation of platelet indices in mares.
Chronobiology international    July 31, 2026   1-12 doi: 10.1080/07420528.2026.2710242
Satué K, La Fauci D, Colomer-Selva R, Cravana C, Fazio E.Platelet indices provide valuable information on platelet activation, heterogeneity, and production kinetics, yet their physiological variability remains poorly characterized in horses. Although seasonal changes in platelet count have been described, the seasonal modulation of derived platelet indices in mares remains poorly understood. The aim of this study was to evaluate the seasonal variation of platelet count and derived platelet indices in clinically healthy mares from the Valencia region (Spain), and to assess their interrelationships. Forty clinically healthy Spanish Purebred mares (6-...
Technical note on cervical epidural catheterization in two adult horses: Injectate distribution and epidural space effects.
Veterinary surgery : VS    July 30, 2026   doi: 10.1111/vsu.70140
O'Scanaill O, Moorman VJ, Perlini M, Reed RA.To determine the caudalmost extent of diffusion of contrast media administered through a cervical epidural catheter (CEC) and to describe pathologic changes associated with maintaining an indwelling CEC for up to 17 days. Methods: Pilot study. Methods: Two mature horses. Methods: CECs were placed under ultrasound guidance in two horses. Both horses were injected with 5 mL 50% Iohexol contrast solution, followed by radiographs of catheter insertion site to confirm placement. A total volume of 15 mL contrast solution was injected in 5 mL aliquots up to 25 min post-initial injection. La...
Evaluation of Microvascular Flow Imaging and Power Doppler Ultrasonography in an Equine Model of Induced Superficial Digital Flexor Tendonitis. Garcia-Collao MR, Ortved K, Stefanovski D, Christensen JL, Underwood C.Superficial digital flexor tendon (SDFT) injuries are common in athletic horses and are associated with prolonged healing and high reinjury rates. Conventional ultrasonography provides structural information but limited physiologic assessment. This study compared microvascular imaging (MVI) and Power Doppler (PD) for evaluating vascular changes in a collagenase-induced equine SDFT injury model and assessed the effect of scanning technique on vascular signal detection. Eight adult Thoroughbred horses underwent bilateral collagenase-induced SDFT injury, with one forelimb randomly assigned to int...
Approaches to Thoroughbred Horse Identification in Diverse Sample Types Using Multiplexed SNP-PCR Sequencing Panels.
Animal genetics    July 29, 2026   Volume 57, Issue 4 e70170 doi: 10.1002/age.70170
Maniego J, Harding C, Hincks P, Habershon-Butcher J, Ryder E.The ability to determine the identity of equine samples would be highly advantageous in cases of ambiguous sample source, as individual-specific controls for gene editing detection, or forensic examination of suspect biological materials in potential doping cases. To this end, a SNP-PCR sequencing-based panel comprising 93 markers in one reaction was designed and investigated for use in Thoroughbred horses. Marker amplification performance and discriminating power were calculated against a population survey of 264 Thoroughbred whole blood samples from routine doping testing. The sensitivity of...
Favorable survival of horses with guttural pouch mycosis following hospital-based treatment.
Journal of the American Veterinary Medical Association    July 29, 2026   1-6 doi: 10.2460/javma.26.04.0248
Phillips NAI, McOnie RC, Delvescovo B, Radcliffe R, Ducharme NG, Hackett ES.To report the clinical outcomes and survival time in horses undergoing treatment of guttural pouch mycosis. Unassigned: Client-owned horses with guttural pouch mycosis admitted between 2005 and 2024 for evaluation and treatment were identified by medical record search. Signalment, disease history, and surgical and treatment details were recorded. Owners were contacted for follow-up information. Unassigned: 41 horses with guttural pouch mycosis were identified, of which 28 had epistaxis or a history of epistaxis on presentation. Thirty-five horses underwent surgical treatment, and the procedure...