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Topic:Equine Medicine

Equine Medicine encompasses the study and application of medical practices specifically related to the health and well-being of horses. This field involves the diagnosis, treatment, and prevention of diseases and disorders affecting equine species. It covers a wide range of topics, including internal medicine, surgery, reproduction, and pharmacology. Research in equine medicine often focuses on understanding the physiological and pathological processes unique to horses, as well as developing effective therapeutic interventions. This page aggregates peer-reviewed research studies and scholarly articles that explore various aspects of equine medicine, providing insights into the latest advancements and methodologies in the care and management of horse health.
Molecular detection of 7SL-derived small RNA is a promising alternative for trypanosomosis diagnosis.
Transboundary and emerging diseases    July 31, 2020   Volume 67, Issue 6 3061-3068 doi: 10.1111/tbed.13744
Verney M, Grey F, Lemans C, Géraud T, Berthier D, Thévenon S, Rincé A, Hans A, Morrison L, Hébert L.Equine trypanosomosis comprises different parasitic diseases caused by protozoa of the subgenus Trypanozoon: Trypanosoma equiperdum (causative agent of dourine), Trypanosoma brucei (nagana) and Trypanosoma evansi (surra). Due to the absence of a vaccine and the lack of efficacy of the few available drugs, these diseases represent a major health and economic problem for international equine trade. Development of affordable, sensitive and specific diagnostic tests is therefore crucial to ensure the control of these diseases. Recently, it has been shown that a small RNA derived from the 7SL gene ...
Author Correction: Detection of Neorickettsia risticii, the agent of Potomac horse fever, in horses from Rio de Janeiro, Brazil.
Scientific reports    July 29, 2020   Volume 10, Issue 1 13001 doi: 10.1038/s41598-020-69584-w
Paulino PG, Almosny N, Oliveira R, Viscardi V, Müller A, Guimarães A, Baldani C, da Silva C, Peckle M, Massard C, Santos H.An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Large Animal Emergency Relief Services-A Model for University Engagement With Private Practitioners and Development of Practice Readiness for Veterinary Students.
Frontiers in veterinary science    July 17, 2020   Volume 7 403 doi: 10.3389/fvets.2020.00403
Graves MT, Anderson DE, DeNovo RC.Large animal teaching hospitals often struggle to maintain consistent teaching caseloads, which are affected by seasonal variations, economic pressures, increased abilities of local large animal practices to hospitalize large animals, and client intolerance for the operational needs of an academic mission. Non-academic large animal practices enjoy a more consistent caseload but suffer from a lack of emergency relief and a limited ability to share emergency duties, which may have adverse effects on work-life balance. An academic, on-farm, large animal emergency relief service can combine multip...
Genetics, Genomics, and Emergent Precision Medicine 12 Years After the Equine Reference Genome Was Published.
The Veterinary clinics of North America. Equine practice    July 14, 2020   Volume 36, Issue 2 173-181 doi: 10.1016/j.cveq.2020.04.002
MacLeod JN, Kalbfleisch TS.The first equine reference genome was completed in 2007 and published in 2009. This major accomplishment has enabled equine science to advance in ways that broadly parallel the transformative impact that genomics has had on many animal species including humans. A conceptual overview of reference genomes, genome annotation, and the major implications for equine science is presented. The relationship between genomic sequencing and the accelerating application of precision P4 medicine is discussed in the context of human and equine patients. Emergent technologies built on the foundation of genomi...
In slow pace towards the proteome of equine body fluids.
Journal of proteomics    June 19, 2020   Volume 225 103880 doi: 10.1016/j.jprot.2020.103880
Chiaradia E, Miller I.Equine medicine represents a relevant field of veterinary science and the horse industry generates a significant economic impact. Horses can be involved in different sport disciplines, meat production, work and recreational purposes. Horses are also important for human health as they can be used as animal models for studying human diseases and in equine-assisted therapy. This review summarizes the data related to body fluids such as plasma/serum, urine, cerebrospinal fluid, synovial fluid, saliva, bronchoalveolar lavage fluid and peritoneal fluid obtained using proteomic analysis. Horse body f...
A missense mutation in ASIP is associated with light point variation in donkeys.
Animal genetics    April 20, 2020   Volume 51, Issue 4 629 doi: 10.1111/age.12940
Yu Y, Shang S, Zhang X, Wang Z, Dang W, Zhang J, Zhu Y, Dang R, Irwin DM, Zhang S.No abstract available
Congenital phimosis causing preputial swelling in a newborn foal.
The Canadian veterinary journal = La revue veterinaire canadienne    March 14, 2020   Volume 61, Issue 3 247-250 
Canisso IF, Ellerbrock RE, Wilkins PA.An 18-hour-old colt was presented for abdominal discomfort, preputial swelling, and frequent posturing to urinate. Examination of the scrotum confirmed 2 testes and no scrotal or inguinal hernia. Transabdominal ultrasound identified a distended bladder and no free fluid in the peritoneal cavity. Inspection of the preputial cavity revealed that the internal lamina of the prepuce was mostly attached to the glans penis. The preputial cavity was lubricated and manual traction was applied to detach the internal lamina of the prepuce from the glans penis. The colt urinated spontaneously 1 hour after...
Screening and Identification of Pathogen Box® Compounds with anti-Trypanosoma evansi Activity.
Acta tropica    February 26, 2020   Volume 206 105421 doi: 10.1016/j.actatropica.2020.105421
Canever MF, Miletti LC.The development of new drugs targeting neglected animal diseases is imperative. In Asia and South America, Trypanosoma evansi is a pathogen that affects horses and other species, causing economic losses associated with reduced animal productivity and death. In order to accelerate the identification of drugs with activity against neglected diseases, Medicines for Malaria Venture has developed Pathogen Box®, a library of 400 different molecules. The present work aimed to identify compounds present in the Pathogen Box® library, measuring in vitro activity against T. evansi. Among the 400 compou...
[Professional entry into equine medicine].
Schweizer Archiv fur Tierheilkunde    February 1, 2020   Volume 162, Issue 2 107-112 doi: 10.17236/sat00247
Stoller N, Christen G, Graubner C.In the present study phone interviews on working hours, salary, professional satisfaction and other topics were carried out with 30 equine veterinarians. None of the participants had more than five years of work experience. The gross annual wages ranged from CHF 36'400 to CHF 91'500. The study participants worked 42 to 93 hours per week. Only 13% were moderately satisfied with the job, the remaining participants were satisfied to highly satisfied. Sixty percent of the study participants were dissatisfied with their wages and wished to be paid according to the Swiss Veterinary Association (GST...
Maturation of the equine medial femoral condyle osteochondral unit.
Osteoarthritis and cartilage open    January 27, 2020   Volume 2, Issue 1 100029 doi: 10.1016/j.ocarto.2020.100029
Lemirre T, Santschi E, Girard C, Fogarty U, Chapuis L, Richard H, Beauchamp G, Laverty S.The juvenile equine medial femoral condyle (MFC) is frequently affected with radiographic changes (sclerosis and subchondral lucencies) that arise at a similar site to juvenile osteochondritis dissecans (JOCD) in children. There is little information on maturation of the MFC. To describe the normal development of the equine MFC osteochondral unit from birth to 2 years. Unassigned: Micro CT, histology and immunohistochemistry were performed on healthy equine MFCs (n = 29) at sites where lesions occur. Parameters assessed included: cartilage thickness; the epiphyseal growth plate cartilage org...
Prognostic value of colonic and peripheral venous lactate measurements in horses with large colon volvulus.
Veterinary surgery : VS    January 9, 2020   Volume 49, Issue 3 472-479 doi: 10.1111/vsu.13361
Orr KE, Baker WT, Lynch TM, Hughes FE, Clark CK, Slone DE, Fogle CA, Gonzalez LM.To determine the prognostic value of (1) colonic venous lactate or peripheral lactate values obtained before and after manual correction of a large colon volvulus and (2) a combination of variables including pelvic flexure biopsy. Methods: Prospective clinical study. Methods: Forty adult horses in which large colon volvulus was diagnosed intraoperatively. Methods: Colonic venous, peripheral venous, and arterial blood samples were collected to measure lactate values before and after manual correction. Mucosal biopsy samples were obtained in cases that underwent enterotomy or colonic resection a...
[Colonel Hermann Schwyter, equine surgeon, a formative personality of equine medicine].
Schweizer Archiv fur Tierheilkunde    January 4, 2020   Volume 162, Issue 1 53-60 doi: 10.17236/sat00243
Meier H.The biography of Colonel Hermann Schwyter, equine surgeon of the Swiss Army from 1928 to 1937, and the history of training of farriers in Switzerland since the 18th century are presented. Hermann Schwyters dissertation examined the changes of equine hoof confirmation as a result of standing and gait in approximately 2,000 horses and numerous anatomical specimens. He defines the foot placement, describes possible variations, their causes and effects. Significant is also his study of the compression pathology in horses and mules. His recommendations are still valid today. The present article ref...
Morphological and Imaging Evaluation of the Metacarpophalangeal and Metatarsophalangeal Joints in Healthy and Lame Donkeys.
Journal of equine veterinary science    December 26, 2019   Volume 88 102904 doi: 10.1016/j.jevs.2019.102904
El-Gendy SAA, Alsafy MAM, Rutland CS, El-Khamary AN, Abu-Ahmed HM, El-Kammar MH.The donkey is of socio-economic value yet imaging techniques in both healthy and abnormal limbs are a limiting factor in research and medicine. The objective was to determine anatomical features of both healthy and clinically abnormal donkey metacarpophalangeal and metatarsophalangeal joints (n = 13) using anatomical dissection, casting, X-ray and computed tomography. The joint capsule contained two palmar/plantar and two dorsal recesses. The proximal-palmar or plantar recess was larger than the distodorsal recess and potential sites of approaches to the recesses were determined. Soft tissue ...
Can Extracorporeal Shockwave Promote Osteogenesis of Equine Bone Marrow-Derived Mesenchymal Stem Cells In Vitro?
Stem cells and development    December 17, 2019   Volume 29, Issue 2 110-118 doi: 10.1089/scd.2019.0202
Colbath AC, Kisiday JD, Phillips JN, Goodrich LR.Both bone marrow-derived mesenchymal stem cells (BMDMSCs) and extracorporeal shockwave (ESW) have shown promise for enhancing fracture repair. If exposure of BMDMSCs to ESW enhances osteogenic differentiation, these therapies may be combined in vivo or used as a method for preconditioning BMDMSCs. The objective of this study was to determine the effect of ESW on the osteogenic ability of equine BMDMSCs. We hypothesized that ESW would promote osteogenesis evidenced by increased gene expression, alkaline phosphatase (ALPL) expression, slide morphologic score, and protein expression. BMDMSCs were...
Time of first polar body extrusion affects the developmental competence of equine oocytes after intracytoplasmic sperm injection.
Reproduction, fertility, and development    November 21, 2019   Volume 31, Issue 12 1805-1811 doi: 10.1071/RD19248
Rodríguez MB, Gambini A, Clérico G, Ynsaurralde-Rivolta AE, Briski O, Largel H, Sansinena M, Salamone DF.Assisted reproduction techniques (ARTs) have become widespread in the equine breeding industry. In particular, the combination of oocyte recovery from live mares followed by IVM and intracytoplasmic sperm injection (ICSI) has increased markedly among the ARTs used with valuable or low-fertility animals. There is currently no consensus among research groups regarding the optimal oocyte maturation period to produce high-quality embryos. In this study, we report the maturation dynamics of equine oocytes at different time points, from 20 to 40h (Experiment 1). In addition, in Experiment 2, equine ...
What is your diagnosis? Nasal lesion in a horse with exophthalmos.
Veterinary clinical pathology    November 7, 2019   Volume 48, Issue 4 771-773 doi: 10.1111/vcp.12790
Zibura AE, Manning LK, Gwynn A, Sharkey L, de Linde Henriksen M, Coppelman E, O'Brien TD.No abstract available
Piroplasmosis in Italian Standardbred Horses: 15 Years of Surveillance Data.
Journal of equine veterinary science    October 18, 2019   Volume 83 102813 doi: 10.1016/j.jevs.2019.102813
Padalino B, Rosanowski SM, Di Bella C, Lacinio R, Rubino GTR.This study aimed to document the prevalence of chronic equine piroplasmosis (EP) in poorly performing Standardbred racehorses and to explore associations between the disease and sex, age, and hematological parameters. Blood was collected between 2004 and 2018; blood cell counts were performed using a cell counter analyzer, biochemical parameters using a photometer, and serum proteins using agarose gel electrophoresis. Blood smears were prepared, colored with a modified Giemsa, and an experienced technician identified the presence of protozoa. The horses were categorized into piroplasmosis posi...
Phaeohyphomycotic Rhinitis Caused by Bipolaris hawaiiensis in a Horse.
Journal of equine veterinary science    October 1, 2019   Volume 82 102798 doi: 10.1016/j.jevs.2019.102798
Legere RM, Wooldridge AA, Sandey M, Hanson RR, Cole R.This case represents the first reported case of Bipolaris hawaiiensis infection in an equid, and its aggressive clinical course. This case provides important descriptive and prognostic information for horses diagnosed with phaeohyphomycotic rhinitis. A 19-year-old American Quarter Horse mare was presented for second opinion of stertor and exercise intolerance of four-month duration. Endoscopy revealed generalized, proximal nasal edema, and computed tomography identified a soft tissue mass eroded through the rostral nasal bone. Biopsy of the mass was identified as a fungal granuloma caused by B...
Delayed onset vagus nerve paralysis after occipital condyle fracture in a horse.
Journal of veterinary internal medicine    September 26, 2019   Volume 33, Issue 6 2780-2785 doi: 10.1111/jvim.15581
Martin-Giménez T, Cruz AM, Barragán A, Montero E, Sanchez PG, Caballero G, Corradini I.Occipital condylar fractures (OCFs) causing delayed onset lower cranial nerve paralysis (LCNPs) are rare. We present a 7-year-old Friesian horse with delayed onset dysphagia caused by vagus nerve (CNX) paralysis and suspicion of glossopharyngeal nerve (CNIX) paralysis developed several days after a minor head injury. Endoscopic examination revealed right laryngeal hemiplegia and intermittent dorsal displacement of the soft palate. An area of submucosal hemorrhage and bulging was appreciated over the dorsal aspect of the medial compartment of the right guttural pouch. Radiological examination o...
Diffusion of fluoroquinolones into equine fetal fluids did not induce fetal lesions after enrofloxacin treatment in early gestation.
Veterinary journal (London, England : 1997)    September 7, 2019   Volume 253 105376 doi: 10.1016/j.tvjl.2019.105376
Ellerbrock RE, Canisso IF, Podico G, Roady PJ, Uhl E, Lima FS, Li Z.While recent work demonstrated that enrofloxacin and ciprofloxacin reach the fetoplacental unit without causing obvious lesions in the 9-month-old equine fetus or resulting foal, many practitioners still hesitate to prescribe a fluoroquinolone during pregnancy. Since early gestation is a critical time for fetal skeletal development, if fluoroquinolones are chondrotoxic to the fetus at any point during gestation, this period would be important. The aim of this study was to assess the effects of 2 weeks' exposure to enrofloxacin on the equine fetus between 46 and 60 days gestation. Twelve pregna...
Dear Donkey and Mule: You Deserve More Appreciation and Better Medicine.
The Veterinary clinics of North America. Equine practice    September 3, 2019   Volume 35, Issue 3 xiii-xiv doi: 10.1016/j.cveq.2019.08.015
Toribio RE.No abstract available
State-of-the-Art Diagnostic Methods to Diagnose Equine Spinal Disorders, With Special Reference to Transcranial Magnetic Stimulation and Transcranial Electrical Stimulation.
Journal of equine veterinary science    September 3, 2019   Volume 81 102790 doi: 10.1016/j.jevs.2019.102790
Journée SL, de Meeus d'Argenteuil C, De Maré L, Boshuizen B, Vanderperren K, Journée LH, de Bruijn M, Bergmann W, Delesalle C.Spinal cord disorders are a common problem in equine medicine. However, finding the site of the lesion is challenging for veterinarians because of a lack of sensitive diagnostic methods that can assess neuronal functional integrity in horses. Although medical imaging is frequently applied to help diagnose corticospinal disorders, this approach does not reveal functional information. For the latter, transcranial magnetic stimulation (TMS) and more recently transcranial electrical stimulation (TES) can be useful. These are brain stimulation techniques that create either magnetic or electrical fi...
Equine cheek tooth extraction: Comparison of outcomes for five extraction methods.
Equine veterinary journal    July 30, 2019   Volume 52, Issue 2 181-186 doi: 10.1111/evj.13150
Caramello V, Zarucco L, Foster D, Boston R, Stefanovski D, Orsini JA.Post-operative complications are reported for all methods of equine cheek tooth extraction but not all methods carry the same risks. An outcome comparison for commonly used methods is needed so that clinicians can make informed treatment decisions. Objective: We conducted a side-by-side comparison of five cheek tooth extraction methods, comparing types and incidence of complications among oral extraction, tooth repulsion (three surgical approaches) and lateral buccotomy techniques. Methods: Retrospective clinical study using hospital medical records. Methods: Medical records of all horses unde...
Sex identification in horses (Equus caballus) based on the gene pair NLGN4X/NLGN4Y.
Animal genetics    July 10, 2019   Volume 50, Issue 5 551 doi: 10.1111/age.12823
Zaffalon S, Latz A, Krasteva-Christ G, Maxeiner S.No abstract available
And Now for Something Completely Different: Some Controversies in Equine Medicine, Surgery, and Reproduction.
The Veterinary clinics of North America. Equine practice    July 8, 2019   Volume 35, Issue 2 xi-xii doi: 10.1016/j.cveq.2019.05.001
MacKay RJ.No abstract available
Girthiness: Retrospective Study of 37 Horses (2004-2016).
Journal of equine veterinary science    June 8, 2019   Volume 79 100-104 doi: 10.1016/j.jevs.2019.05.025
Millares-Ramirez EM, Le Jeune SS.Girth aversion or girthiness is a nonspecific clinical sign anecdotally associated with multiple conditions in the horse (behavioral problems, gastric ulcers, back pain); however, studies have not been conducted to definitively correlate this clinical sign to specific pathologies. This retrospective study aims to describe the clinical signs and final diagnoses of 37 horses evaluated at the University of California, Davis with a presenting complaint of girthiness. Medical records of all horses presented to the veterinary hospital between 2004 and 2016 for girthiness were reviewed. Twelve horses...
Analysis of neurofilament concentration in healthy adult horses and utility in the diagnosis of equine protozoal myeloencephalitis and equine motor neuron disease.
Research in veterinary science    May 11, 2019   Volume 125 1-6 doi: 10.1016/j.rvsc.2019.04.018
Morales Gómez AM, Zhu S, Palmer S, Olsen E, Ness SL, Divers TJ, Bischoff K, Mohammed HO.Neurofilaments (NFs) are structural proteins of neurons that are released in significant quantities in the cerebrospinal fluid and blood as a result of neuronal degeneration or axonal damage. Therefore, NFs have potential as biomarkers for neurologic disorders. Neural degeneration increases with age and has the potential to confound the utility of NFs as biomarkers in the diagnosis of neurologic disorders. We investigated this relationship in horses with and without neurological diagnosis. While controlling for horse type (draft, pleasure, and racing), we evaluated the relationship between ser...
A Suspected Case of Rocky Mountain Spotted Fever in an Adult Horse in the Southeastern United States.
Journal of equine veterinary science    May 11, 2019   Volume 78 134-137 doi: 10.1016/j.jevs.2019.05.003
Freese S, Sheats MK.A 20-year-old Paint gelding was evaluated for fever of unknown origin. History and clinical signs were consistent with potential tick-borne disease. Samples were collected and submitted for tick-borne disease panel, herpes virus, complete blood count, and serum biochemistry. Based on physical examination findings and vaccination history, the gelding was treated for suspected tick-borne disease with oxytetracycline (8 mg/kg intravenously BID) for 5 days, followed by doxycycline (10 mg/kg PO BID) for an additional 5 days. Although titers to Borrelia burgdorferi, Anaplasma phagocytophilum, an...
First description of Theiler’s disease-associated virus infection and epidemiological investigation of equine pegivirus and equine hepacivirus coinfection in Brazil.
Transboundary and emerging diseases    May 8, 2019   Volume 66, Issue 4 1737-1751 doi: 10.1111/tbed.13210
Figueiredo AS, de Moraes MVDS, Soares CC, Chalhoub FLL, de Filippis AMB, Dos Santos DRL, de Almeida FQ, Godoi TLOS, de Souza AM, Burdman TR....Recent advances in the study of equine pegivirus (EPgV), Theiler's disease-associated virus (TDAV) and equine hepacivirus (EqHV) highlight their importance to veterinary and human health. To gain some insight into virus distribution, possible risk factors, presence of liver damage and genetic variability of these viruses in Brazil, we performed a cross-sectional study of EPgV and TDAV infections using a simultaneous detection assay, and assessed EqHV coinfection in different horse cohorts. Of the 500 serum samples screened, TDAV, EPgV and EPgV-EqHV were present in 1.6%, 14.2% and 18.3%, respec...
Potential new sources of hypoglycin A poisoning for equids kept at pasture in spring: a field pilot study.
The Veterinary record    May 2, 2019   Volume 184, Issue 24 740 doi: 10.1136/vr.104424
Votion DM, Habyarimana JA, Scippo ML, Richard EA, Marcillaud-Pitel C, Erpicum M, Gustin P.Equine atypical myopathy in Europe results from hypoglycin A (HGA) exposure through the ingestion of samaras or seedlings of the sycamore maple tree. This pilot study aimed at better defining sources of HGA intoxication in spring. Samaras fallen on the ground and then seedlings were collected at two-week intervals from sycamore, Norway, and field maple trees over the spring 2016. In early April, rainwater from wet seedlings collected after a rainy night was harvested to be analysed. Mid-May, samaras of the box elder, common ash, and inflorescences of sycamore maples were collected on the tree....
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