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Topic:Lameness

Lameness in horses is a condition characterized by an abnormal gait or stance due to pain or mechanical dysfunction affecting the limbs or spine. It is a common issue in equine practice and can result from a variety of causes, including injury, infection, or degenerative diseases. Lameness can affect a horse's performance and quality of life, making accurate diagnosis and management important for equine health. Diagnostic techniques often include physical examination, imaging, and gait analysis. This page aggregates peer-reviewed research studies and scholarly articles that explore the etiology, diagnostic methods, and management strategies for lameness in horses.
Clinical study on the effect of low-intensity pulsed ultrasound on healing of proximal sesamoid bone fractures in Yili horses.
Scientific reports    August 28, 2025   Volume 15, Issue 1 31697 doi: 10.1038/s41598-025-17424-0
Zhang Z, Li J, Mai Z, Yang Y, Fu H, Cao X, Li T, Guo Q, Ma Y.The incidence of sports injuries in horses is increasing, thus accurate assessment, diagnosis, and treatment are critical. Among common sports-related injuries, proximal sesamoid bone fractures (PSBFs) are one of the most frequent types. To investigate the effects of low-intensity pulsed ultrasound (LIPUS) on imaging and hematological parameters of PSBFs, providing a clinical reference for the diagnosis and treatment of PSBFs in racehorses. After clinical diagnosis and radiographic examination confirmed the disease and its location, the affected horses were randomly divided into two groups: th...
Inflammatory response following intra-articular injection of decellularized porcine amnion/chorion in horses.
Veterinary surgery : VS    August 25, 2025   Volume 54, Issue 7 1454-1462 doi: 10.1111/vsu.70005
Cormier KV, Fontenot RL, Eddy A, Williams ML, Wills RW, Jumper WI, Mochal-King CA.The objective of the study was to evaluate effects of intra-articular decellularized porcine amnion/chorion suspension (dPACLS) in horses. Methods: Controlled, randomized, prospective study. Methods: A total of 10 adult horses. Methods: One randomly selected radiocarpal joint (RCJ) was injected with a high dose (HD) of 50 mg (n = 5) or low dose (LD) of 5 mg of dPACLS (n = 5). The contralateral RCJ received saline as control. Systemic serum amyloid A (SAA), synovial fluid analysis (including SAA) and subjective lameness evaluation were performed prior to injection (time 0) and 24, 4...
High-field magnetic resonance imaging enables diagnosis of central tarsal bone fractures in performance horses with lameness localized to the proximal metatarsus and tarsus.
Journal of the American Veterinary Medical Association    August 22, 2025   Volume 264, Issue 1 96-103 doi: 10.2460/javma.25.05.0346
Myers TJ, Sampson SN, Glass KP, Russell LA.Central tarsal bone (CTB) fractures are challenging to diagnose, and cross-sectional imaging is required for definitive characterization and surgical planning. This retrospective case series aims to provide the first description of high-field (3-T) MRI characteristics of CTB fractures, concurrent pathology, and clinical presentation in 8 performance horses. Unassigned: 8 horses (9 limbs) diagnosed with a CTB fracture on high-field MRI at one tertiary referral hospital between 2013 and 2023 were identified via electronic medical records search. Unassigned: Quarter Horses (6 of 8) used for Weste...
Refinement of the Lipopolysaccharide-Induced Synovitis Model in Equine Middle Carpal Joints.
Animals : an open access journal from MDPI    August 22, 2025   Volume 15, Issue 17 2474 doi: 10.3390/ani15172474
Duggan MJS, Kearney C, Baltrimaite M, Labberté MC, Gibney R, Brama PAJ.The aim of this study was to refine the lipopolysaccharide (LPS)-induced synovitis model in normal carpal joints of Thoroughbred horses by comparing two low LPS doses. A further aim was to investigate the relationship between the induced synovitis and lameness. The study design consisted of two phases using nine horses with a unilateral crossover design and a within-animal saline control. Synoviocentesis was performed at post-injection hour (PIH) 0, 8, 24, 72 and 168, allowing for synovial fluid cytology and biomarker analysis. Objective gait and thermographic analysis were used to objectively...
Imaging Findings of Congenital Distal Interphalangeal Joint Dysplasia in a 3-Month-Old Friesian Foal. Giessen EJM, Stas EKL, Grinwis GCM, Veraa S.A 3-month-old Friesian colt presented with severe, progressive distal limb lameness in two limbs. Radiographic and postmortem full-body CT imaging revealed severe articular deforming osteolysis and osteoproliferation at the dorsodistal navicular bone margin and the adjacent distal phalanx proximo-palmar/proximo-plantar margin in two limbs, with the remainder of the distal interphalangeal joint being unaffected. Multiple other joints showed small osteolytic subchondral defects. Postmortem histopathological examination confirmed focal joint disease of both distal interphalangeal joints, without ...
Exploring Monthly Variation of Gait Asymmetry During In-Hand Trot in Thoroughbred Racehorses in Race Training.
Animals : an open access journal from MDPI    August 20, 2025   Volume 15, Issue 16 2449 doi: 10.3390/ani15162449
Pfau T, Forbes B, Sepulveda-Caviedes F, Chan Z, Weller R.Based on fundamental mechanics, movement and force associate head and pelvic movement asymmetry with asymmetry of force production. We investigate, how often racehorses undergoing strenuous training regimens show evidence of switching between "preferred" limbs, i.e. one limb producing increased force, when assessed at monthly intervals? We hypothesize that clinical asymmetry thresholds designed for "detecting lameness" are frequently exceeded and that when applying previously established Thoroughbred-specific repeatability values, horses rarely switch between showing left- and right-sided asym...
Correction: Association between radiographic equine distal phalanx characteristics and absence, presence and type of horseshoes.
Frontiers in veterinary science    August 18, 2025   Volume 12 1675356 doi: 10.3389/fvets.2025.1675356
Ennsmann LH, Licka TF.[This corrects the article DOI: 10.3389/fvets.2025.1598038.].
Lateromedial and oblique radiographs detect most fetlock pathologies as effectively as a full series in horses.
Equine veterinary journal    August 13, 2025   doi: 10.1111/evj.70073
Northwood A, Berner D.Radiographic protocols for the metacarpo-/tarsophalangeal joint during pre-purchase examinations (PPE) vary internationally, but their impact on pathology detection remains unclear. Optimising imaging protocols is essential to balance diagnostic accuracy with workflow efficiency and radiation exposure. Objective: To evaluate the effect of different radiographic view combinations on fetlock pathology detection and observer agreement in a PPE context; hypothesising that detection rates vary with view selection. Methods: Retrospective observational study. Methods: Two observers reviewed fetlock r...
Ultrasound-Guided Radiofrequency Ablation and Pulsed Radiofrequency Treatment for Chronic Lameness Due to Distal Forelimb Disease in Horses: A Pilot Study.
Animals : an open access journal from MDPI    August 10, 2025   Volume 15, Issue 16 2341 doi: 10.3390/ani15162341
Amari M, Brioschi FA, Auletta L, Ravasio G.Radiofrequency ablation (RFA) and pulsed radiofrequency (PRF) are non-pharmacological techniques employed in humans for chronic pain, but their veterinary application is unexplored. This pilot study evaluated clinical effects of RFA and PRF in twenty-four horses with chronic distal forelimb lameness. Ultrasound-guided RFA (N = 8; 60-90 °C, 2-8 min) or PRF (N = 16; 42 °C; 12 min) was applied to palmar digital nerves. Lameness was scored (American Association of Equine Practitioners scale) at baseline and monthly for six months (T1-T6). At T2, partial- and non-responders in both groups receive...
Clinical insights: Musculoskeletal disorders of the sports horse.
Equine veterinary journal    August 6, 2025   Volume 57, Issue 5 1152-1160 doi: 10.1111/evj.14553
Morgan R, Ortved K, Clayton HM, Oosterlinck M.No abstract available
Comments on MacKechnie-Guire et al. (2024): Noseband type and tightness level affect pressure on the horse’s face at trot.
Equine veterinary journal    August 1, 2025   doi: 10.1111/evj.14549
Doherty O, Fenner K, Winther Christensen J, McLean A, Thomson P, Uldahl M, McGreevy P.No abstract available
Does Low-Field MRI Tenography Improve the Detection of Naturally Occurring Manica Flexoria Tears in Horses?
Animals : an open access journal from MDPI    July 31, 2025   Volume 15, Issue 15 2250 doi: 10.3390/ani15152250
Aßmann AD, Sànchez-Andrade JS, Argüelles D, Bischofberger AS.Diagnosing digital flexor tendon sheath (DFTS) pathologies, particularly manica flexoria (MF) tears, can be challenging with standard imaging modalities. Standing low-field MRI tenography (MRIt) may improve the detection rate of MF tears. This study aimed to compare ultrasonography, contrast radiography, pre-contrast MRI, and MRIt to detect naturally occurring MF lesions in horses undergoing tenoscopy. Ten horses with a positive DFTS block, which underwent contrast radiography, ultrasonography, MRI, MRIt, and tenoscopy were included. Two radiologists evaluated the images and recorded whether a...
Outcomes of diode laser-facilitated ankylosis of the distal tarsal joints in horses: A retrospective study of 64 cases.
Veterinary surgery : VS    July 28, 2025   doi: 10.1111/vsu.14312
Sanchez-Arjona R, Lopez Cruz C, Hague BA, Jayawickrama J, Kamm JL.To evaluate the outcomes of diode laser-facilitated (DLF) ankylosis using different surgical techniques to treat distal tarsal osteoarthritis (OA) in horses. Methods: Retrospective cohort study. Methods: A total of 64 client-owned horses with distal tarsal OA treated with DLF ankylosis between 2011 and 2021 in a referral hospital were included. Methods: DLF ankylosis techniques included: intra-articular diode laser (L), diode laser with periarticular drilling (L + D) and diode laser with cuboidal bone fenestration (L + F). Horses requiring a second surgery formed a fourth group (T). Ou...
Normal MRI features of the manica flexoria in horses and evaluation of the anatomic variability between forelimbs and hindlimbs.
PloS one    July 21, 2025   Volume 20, Issue 7 e0327880 doi: 10.1371/journal.pone.0327880
Miles S, McCauley C, Carossino M, Del Piero F, Liu CC, Gaschen L.Manica flexoria tears are increasingly recognized as a cause of lameness in horses resulting in a need for improved pre-operative diagnosis. Partial tears are difficult to pre-operatively diagnose and thus research for diagnostics of manica flexoria tears has been seen in increasing frequency over the past decade, though a deficit of information exists for the features of this structure on MRI, which is best suited for evaluation of soft tissues. The goal is to perform an observational study on the morphometry of the normal manica flexoria prospectively and describe it retrospectively on MRI. ...
Innovating for Curriculum Design Using a Text-Mining Exploration of Common Clinical Topics in Equine Primary Care.
Journal of veterinary medical education    July 16, 2025   e20240175 doi: 10.3138/jvme-2024-0175
Batterham R, Allen K, Dickson J, Warman S, Parkin T.To ensure veterinary students are prepared for clinical practice, curricula must provide opportunities for students to learn about the cases most frequently seen in practice. Currently, there is a gap in the literature with regard to the identification of common clinical topics encountered in equine primary care practice in the UK. This study aims to address this gap by utilizing text-mining techniques on electronic medical records (EMRs) to produce a ranked list of the most common clinical topics encountered in equine primary care in the UK. The study included 1,092,731 rows of data from 150,...
Safety study of leucoreduced allogeneic pooled freeze-dried platelet-rich plasma in healthy equine joints.
Frontiers in veterinary science    July 14, 2025   Volume 12 1625431 doi: 10.3389/fvets.2025.1625431
Kooy S, Constant J, Cole R, Boone L.Clinical use of blood-derived intra-articular therapies, such as platelet-rich plasma (PRP), have increased in equine athletes due to their proposed disease-modifying effects. Need for a shelf-stable, allogeneic PRP product with known composition for standardized treatment exists. The objective of this study was to compare systemic and local effects of a single intra-articular injection of equine leucoreduced allogeneic pooled freeze-dried PRP (alloPRP) to a placebo control (saline) in normal, healthy equine joints. Unassigned: Twelve healthy horses were randomly assigned to either control (sa...
Outcome of arthroscopic debridement for the treatment of incomplete third carpal bone slab fractures in racehorses.
Veterinary surgery : VS    July 9, 2025   doi: 10.1111/vsu.14313
Garcia-Collao MR, Curtiss AL, Hogan PM.To describe the outcomes of arthroscopic debridement of third carpal bone (C3) incomplete slab fractures (ISF) in racehorses. Methods: Retrospective case study. Methods: Horses undergoing arthroscopic debridement of ISF of C3. Methods: The medical records of horses surgically treated for ISF of C3 were reviewed. Age, sex, breed, limb, fracture configuration, preoperative radiographs, arthroscopic findings, postoperative intraarticular therapies, and exercise recommendations were recorded. Racing performance was obtained from online databases. Univariable analyses were used to determine associa...
Usefulness of a Computer-Aided Learning Module for Teaching Radiology of the Equine Foot to Clinical Veterinary Students.
Journal of veterinary medical education    June 30, 2025   e20240165 doi: 10.3138/jvme-2024-0165
Tumber MR, Burke MK.Lameness in horses resulting from foot pathology is very common. When investigating the cause of a lameness localised to the foot, the first step is most frequently radiographic imaging. Therefore, being able to identify normal anatomy and recognise pathology on radiographs is important for a veterinary medicine student to learn. Computer-aided learning (CAL) is becoming increasingly utilised in the teaching of students on medicine-related courses, especially post-COVID where online learning has been continued in hybridisation with in-person teaching.In this study, a low-cost CAL module was cr...
Mosaic arthroplasty in equine stifle and fetlock joints: A retrospective study of 31 cases between 1998 and 2023.
Veterinary surgery : VS    June 27, 2025   doi: 10.1111/vsu.14296
Pál Z, Tuska P, Vásárhelyi G, Hangody L, Hurtig M, Kaposi AD, Bodó G.To evaluate the clinical application of equine mosaic arthroplasty for joint surface repair, including outcomes and complications. Methods: Retrospective clinical study. Methods: A total of 31 horses diagnosed with subchondral bone cysts (SBCs) in the femoral condyle (22/31), distal metacarpus (7/31), or metatarsus (2/31). Methods: Medical records of horses that underwent autologous or allogeneic osteochondral graft transplantation were reviewed. Follow-up lasted at least 12 months. Success was determined in terms of improvements in lameness and post-surgical athletic performance, classified...
Indicators of mortality risk in ageing horses.
GeroScience    June 25, 2025   doi: 10.1007/s11357-025-01738-y
Kelemen Z, Vogl C, Torres Borda L, Auer U, Jenner F.Clinical care for patients with limited life expectancy often requires adjustments, prioritizing immediate benefits over long-term outcomes, as the relevance of future complications diminishes. This study identifies indicators of mortality risk in horses with chronic orthopaedic conditions to enhance individualized care and welfare. Over 3 years, 123 chronically lame horses and 6 healthy control horses at an animal sanctuary underwent regular (every 3 months) comprehensive health assessments and activity monitoring using wearable sensors. Data collected included body condition scores, muscul...
Prevalence of musculoskeletal injuries associated with lameness in Australian campdraft horses.
Equine veterinary journal    June 24, 2025   doi: 10.1111/evj.14551
Argue BJ, Labens R.Campdrafting is a unique Australian cow horse sport, which evolved from mustering cattle and is one of Australia's fastest growing equine sports. This discipline is associated with its own unique set of musculoskeletal injuries yet to be reported. Objective: To describe the prevalence, anatomical location, and diagnostic modality used to localise lameness in campdrafting horses to better assist efficient orthopaedic management of the campdraft horse. Methods: Retrospective case series. Methods: Medical records were examined from one private practice equine group and one university veterinary h...
Equine Bone Imaging, Part 2: Role of Nuclear Medicine in Racehorses.
Journal of nuclear medicine technology    June 24, 2025   jnmt.125.270050 doi: 10.2967/jnmt.125.270050
Tually P, Currie G.The horse racing industry, like any sport, must contend with the effects of injuries on an athlete's performance and longevity. Catastrophic fractures linked to preexisting bone fatigue can be prevented with the use of imaging technology, such as the nuclear medicine bone scan. The accessibility and affordability of imaging for racehorses remain obstacles. The conventional role of bone scintigraphy has evolved with the advent of advanced techniques, including MRI, CT, and PET. Concurrently, SPECT has expanded the role of scintigraphy in the racehorse. This article explores the conventional and...
Dual-Energy Computed Tomography for the Detection of Bone Edema-Like Lesions in the Equine Foot: Standing Horses and Cadaveric Specimens.
Veterinary sciences    June 24, 2025   Volume 12, Issue 7 614 doi: 10.3390/vetsci12070614
Germonpré J, Lorenz I, Vandekerckhove LMJ, Duchateau L, Diekhoff T, Vanderperren K.Dual-energy computed tomography (DECT) is a promising advancement for detecting bone edema-like lesions (BME). However, its application in horses remains limited. The aim of this study was to evaluate DECT virtual-non-calcium (VNCa) imaging in the equine foot and establish which confounding factors could influence its applicability in clinical practice. The DECT VNCa map of 14 standing and 5 cadaveric (recumbent) cases with foot-related lameness was scored in consensus by two readers in comparison to MRI. Overall, 17/19 cases demonstrated BME on MRI, whereas 2 did not. Agreement between DECT V...
Ultrasonographic diagnosis of caudoproximal humeral stress fracture in thoroughbred racehorses.
Equine veterinary journal    June 22, 2025   doi: 10.1111/evj.14546
Vaughan B, McKerney ER, Wollenberger C, Cloninger A, Spriet M, Galuppo L, Stover SM.Humeral stress fractures in racehorses can progress to catastrophic fracture if unrecognised. Scintigraphy is the gold standard diagnostic technique but is limited by accessibility and cost. It was hypothesised that ultrasonography could be used to visualise caudoproximal humeral stress fractures. Objective: To determine the utility of ultrasonography to identify caudoproximal humeral stress fractures in racehorses. Methods: Clinical case series. Methods: Seven racehorses that had a clinical history consistent with the presence of a humeral stress fracture were examined using humeral ultrasono...
Objective Evaluation of Gait Asymmetries in Traditional Racehorses During Pre-Race Inspection: Application of a Markerless AI System in Straight-Line and Lungeing Conditions.
Animals : an open access journal from MDPI    June 18, 2025   Volume 15, Issue 12 doi: 10.3390/ani15121797
Meistro F, Ralletti MV, Rinnovati R, Spadari A.Subtle locomotor asymmetries are common in horses and may go unnoticed during routine pre-race clinical inspections, particularly when based solely on subjective evaluation. This study aimed to describe vertical head and pelvic movement asymmetries in racehorses that passed official pre-race inspections at a traditional racing event. Twenty-four horses were analysed using a markerless AI-based gait analysis system while trotting in-hand and during lungeing in both directions. Asymmetry parameters (HDmin, HDmax, PDmin, and PDmax) were extracted from video recordings, with values ≥0.5 consider...
Clinical evaluation of freeze-dried secretome (lyosecretome) for osteoarthritis: a controlled trial in dogs and preliminary safety assessment in horses.
International journal of pharmaceutics    June 16, 2025   Volume 681 125864 doi: 10.1016/j.ijpharm.2025.125864
Berni P, Del Bue M, Conti V, Andreoli V, Ramoni R, Angelone M, Squassino GP, Bari E, Torre ML, Rinaldi M, Dotti S, Rossi R, Yusuf I, Mauri P....Most in vivo studies on MSC-secretome for osteoarthritis (OA) have relied on animal models, using products lacking pharmaceutical quality, not formulated for clinical use, and insufficiently characterized, limiting knowledge of its effectiveness. This study reports veterinary clinical trials on dogs and horses with spontaneous OA: in dogs (26 subjects), the trial is randomized, double-blinded, and controlled; in horses, 5 clinical cases were treated for safety assessment. Treatment consisted of hyaluronic acid with either lyosecretome - a freeze-dried, injectable MSC-secretome obtained through...
Suspensory Ligament Injuries: Diagnosis and Treatment.
The Veterinary clinics of North America. Equine practice    June 14, 2025   S0749-0739(25)00023-9 doi: 10.1016/j.cveq.2025.04.005
Horne CR, Redding WR.The location of a suspensory ligament (SL) injury heavily influences the clinical presentation, prognosis, and treatment options. Diagnostic imaging is necessary to provide an accurate diagnosis and is critical to ensure the institution of the most appropriate treatment. The hindlimb proximal SL in particular can be challenging to diagnosis, carries a guarded prognosis, and typically requires aggressive treatment to achieve soundness.
Techniques for Equine Tendon Tenorrhaphy.
The Veterinary clinics of North America. Equine practice    June 14, 2025   Volume 41, Issue 2 341-355 doi: 10.1016/j.cveq.2025.04.002
Tay A, McMaster M.Equine tendon lacerations are not uncommon secondary to traumatic wounds and degloving lacerations. These wounds are often contaminated and, therefore, basic principles of wound assessment and management are critical to identify the extent of an injury. Ancillary tools to aid physical examination include radiography, ultrasonography, and synoviocentesis (eg, if involving a joint and/or tendon sheath). Prolonged convalescence period, continued external coaptation, and controlled exercise are mainstays of treatment following tenorrhaphy. A poor prognosis for return to full athletic function is e...
Lag screw compression effectively treats proximal subchondral bone cysts and fissures in the first phalanx of mature performance horses.
Journal of the American Veterinary Medical Association    June 13, 2025   Volume 263, Issue 9 1127-1135 doi: 10.2460/javma.25.03.0134
Maguire M, Brusie R.To determine the outcome of skeletally mature performance horses with subchondral bone cysts and fissures in the proximal aspect of the first phalanx treated by lag screw compression. Unassigned: Case records of horses that underwent lag screw compression to treat subchondral bone lesions in the proximal aspect of the first phalanx were reviewed. Performance horses > 5 years old with lameness referrable to the fetlock region; radiographic or other advanced imaging evidence of subchondral bone lesions, with no other concurrent cause for lameness; and at least 6 months of follow-up data were inc...
Desmitis of the palmar or plantar ligaments of the proximal interphalangeal joint: A descriptive case series.
Equine veterinary journal    June 12, 2025   doi: 10.1111/evj.14547
Peeters MWJ, Ott S, van Veggel E, Berner D, Perrier M.Limited reports in the literature are available regarding desmitis of the palmar/plantar ligaments of the proximal interphalangeal joint (PL-PIPJ); the clinical significance of such injuries is unknown. Objective: To describe the ability to differentiate the PL-PIPJ on low-field magnetic resonance (MR) examination. To describe the injury characteristics of the PL-PIPJ on MR examination and the correlation with clinical features and lameness. Methods: Retrospective case series. Methods: Data and MR images of 29 horses were collected from the databases of three institutions. Horses were included...