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Topic:Lameness

Lameness in horses is a condition characterized by an abnormal gait or stance due to pain or mechanical dysfunction affecting the limbs or spine. It is a common issue in equine practice and can result from a variety of causes, including injury, infection, or degenerative diseases. Lameness can affect a horse's performance and quality of life, making accurate diagnosis and management important for equine health. Diagnostic techniques often include physical examination, imaging, and gait analysis. This page aggregates peer-reviewed research studies and scholarly articles that explore the etiology, diagnostic methods, and management strategies for lameness in horses.
Leukocyte-derived and endogenous matrix metalloproteinases in the lamellae of horses with naturally acquired and experimentally induced laminitis.
Veterinary immunology and immunopathology    November 7, 2008   Volume 129, Issue 3-4 221-230 doi: 10.1016/j.vetimm.2008.11.003
Loftus JP, Johnson PJ, Belknap JK, Pettigrew A, Black SJ.Inflammation and dysregulation of endogenous matrix metalloproteinase (MMP) production are implicated in the development of equine laminitis. In this study, we examine quantitative relationships among levels of leukocyte-derived proMMP-9 and MMP-9, lamellar proMMP-2 and MMP-2, and expression of proMMP-2 processing enzymes, MT1-MMP/PACE4, as steps towards determining whether inflammation and dysregulation of endogenous MMP production are independent or co-dependent processes. Methods: Archived samples of lamellae from horses with naturally acquired laminitis (n = 12), and from horses administer...
Evaluation of clinical examination for differential diagnosis of lameness by navicular apparatus or heel pain in horses.
Pakistan journal of biological sciences : PJBS    September 30, 2008   Volume 11, Issue 13 1754-1756 doi: 10.3923/pjbs.2008.1754.1756
Sardari K, Kazemi H.To evaluation of clinical examination for differential diagnosis of navicular region pain from other forms of palmar heel pain in the forelimb in horses the present study was undertaken. Thirty four horses with lameness referable to the palmar aspect of the hoof based on their response to the palmar digital nerves analgesia were divided into 2 groups based on their response to both distal interphalangeal joint and navicular bursa analgesia. Horses that were profoundly improved by both analgesic blocks (distal interphalangeal joint and navicular bursa) were considered to have navicular region p...
[Frequency of diseases and injuries in the Swiss horse population].
Schweizer Archiv fur Tierheilkunde    September 10, 2008   Volume 150, Issue 8 399-408 doi: 10.1024/0036-7281.150.8.399
Knubben JM, Gygax L, Auer J, Fürst A, Staᆲher M.Through a written questionnaire, which was sent to a representatively distributed and randomly selected sample of Swiss horse owners, data of 2912 horses and ponies were acquired to extrapolate prevalence data of health disorders. General questions about the horse and associated factors of housing and use, as well as questions about the current health status and the occurrence of diseases and injuries had been asked. 718 horses (24.7% of the sample) had been examined by a veterinarian within the 12 months prior to the survey. Orthopaedic and traumatic disorders (41.5%) had the largest proporti...
[Drug interactions of phenylbutazone and phenprocoumon in a warmblood gelding].
Schweizer Archiv fur Tierheilkunde    August 22, 2008   Volume 150, Issue 7 352-358 doi: 10.1024/0036-7281.150.7.352
Cohausz O, Müntener CR, Trachsel D, Wimmershoff J, Eser MW.A 15 year old Oldenburger gelding was treated during 3 weeks for laminitis with the anticoagulant phenprocoumone (27 mg orally, once daily) and concurrent administration of phenylbutazone (2-4 g orally, twice daily). After this treatment the animal was presented to the Equine Clinic University of Zurich with a history of acute colic and advanced symptoms of shock. On the basis of the clinical signs and laboratory values, a diagnosis of combined drug induced coagulopathy was made. The horse was treated with the antidote Vitamine-K1 (0.5 mg/kg, subcutaneously). Eventually, the general condition ...
Factors affecting outcome of extensor tendon lacerations in the distal limb of horses. A retrospective study of 156 cases (1994-2003).
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    August 16, 2008   Volume 21, Issue 4 358-364 
Mespoulhès-Rivière C, Martens A, Bogaert L, Wilderjans H.Distal limb lacerations are common injuries in horses, with a better prognosis reported for extensor tendons lacerations compared to flexor tendons lacerations. The objective of the present study was to determine the influence of type and location of injury, modalities of treatment and post surgical complications on the outcome of extensor tendon lacerations. The medical records of 156 horses surgically treated for extensor tendon lacerations over a 10-year period were analysed retrospectively. Information was obtained for 124 horses with a minimum of 18 months follow-up. Statistical analysis ...
Laminitis: drink deep, or taste not the Pierian Spring.
Equine veterinary journal    August 6, 2008   Volume 40, Issue 5 431-432 doi: 10.2746/042516408X320870
Silver IA.No abstract available
Rupture of collateral ligaments in metacarpophalangeal and metatarsophalangeal joints in horses: 17 cases (1999–2005).
Journal of the American Veterinary Medical Association    August 5, 2008   Volume 233, Issue 3 456-462 doi: 10.2460/javma.233.3.456
Tenney WA, Whitcomb MB.To characterize ruptures of collateral ligaments (CLs) in metacarpophalangeal and metatarsophalangeal joints in horses. Methods: Retrospective case series. Methods: 17 horses with ruptured CLs. Methods: Data were obtained from medical records, including signalment, history, clinical signs, ultrasonographic and radiographic findings, treatment, and outcome. Additional follow-up information was obtained from owners or referring veterinarians. Results: The lateral CL was ruptured in 11 horses; the medial CL was ruptured in 6 horses. Ultrasonography revealed ipsilateral rupture of the short and lo...
Quantitative analysis of scintigraphic findings in tibial stress fractures in Thoroughbred racehorses.
American journal of veterinary research    July 3, 2008   Volume 69, Issue 7 886-890 doi: 10.2460/ajvr.69.7.886
Valdés-Martínez A, Seiler G, Mai W, Bolt DM, Mudge M, Dukti SA, Hubert JD.To develop a quantitative method of interpreting tibial scintigrams of Thoroughbred racehorses with tibial stress fractures that may facilitate diagnosis of fractures and to provide prognostic information regarding future performance of affected horses. Methods: 35 Thoroughbred racehorses. Methods: Static bone-phase scintigrams of tibial stress fractures were quantitatively analyzed by use of ratios of the mean radionuclide counts per pixel in a region of interest (ROI) drawn around the area of increased uptake of radiopharmaceutical to mean counts per pixel in a second ROI drawn around an app...
Microbial ecology of the equine hindgut during oligofructose-induced laminitis.
The ISME journal    June 26, 2008   Volume 2, Issue 11 1089-1100 doi: 10.1038/ismej.2008.67
Milinovich GJ, Burrell PC, Pollitt CC, Klieve AV, Blackall LL, Ouwerkerk D, Woodland E, Trott DJ.Alimentary carbohydrate overload is a significant cause of laminitis in horses and is correlated with drastic shifts in the composition of hindgut microbiota. Equine hindgut streptococcal species (EHSS), predominantly Streptococcus lutetiensis, have been shown to be the most common microorganisms culturable from the equine caecum prior to the onset of laminitis. However, the inherent biases of culture-based methods are estimated to preclude up to 70% of the normal caecal microbiota. The objective of this study was to evaluate bacterial population shifts occurring in the equine caecum throughou...
Compressive damage to the deep branch of the lateral plantar nerve associated with lameness caused by proximal suspensory desmitis.
Veterinary surgery : VS    June 20, 2008   Volume 37, Issue 4 328-335 doi: 10.1111/j.1532-950X.2008.00385.x
Tóth F, Schumacher J, Schramme M, Holder T, Adair HS, Donnell RL.To describe pathologic changes in the deep branch of the lateral plantar nerve (DBLPN) of horses determined to be lame because of proximal suspensory desmitis (PSD), and to report the outcome after treatment by excision of a segment of the horses' DBLPN. Methods: Retrospective case series. Methods: Adult horses (n=16). Methods: Horses determined to be lame on one or both pelvic limbs because of PSD were treated by excision of a segment of the DBLPN, and 30 nerves were examined histologically. Owners were contacted to obtain information about the horses >or=6 months after surgery. Results: H...
Desmitis of the distal digital annular ligament in seven horses: MRI diagnosis and surgical treatment.
Veterinary surgery : VS    June 20, 2008   Volume 37, Issue 4 336-344 doi: 10.1111/j.1532-950X.2008.00386.x
Cohen JM, Schneider RK, Zubrod CJ, Sampson SN, Tucker RL.(1) To describe the clinical signs and abnormalities observed on magnetic resonance imaging (MRI) in 7 horses with desmitis of the distal digital annular ligament (DDAL); (2) to describe the normal magnetic resonance (MR) appearance and thickness of the DDAL in health; and (3) to describe a tenoscopic surgical technique for treating horses with desmitis of the DDAL. Methods: Retrospective study. Methods: Horses (n=7) with desmitis of the DDAL. Methods: MR examinations of 20 sound horses were reviewed to determine the normal appearance of the DDAL. Dimensions obtained from these images were com...
Use of magnetic resonance imaging to diagnose the cause of proximal metacarpal pain in a standardbred trotter.
The Veterinary record    June 17, 2008   Volume 162, Issue 24 790-792 doi: 10.1136/vr.162.24.790
Coudry V, Denoix JM, Didierlaurent D, Rossignol F, Audigié F.No abstract available
Clinical and scintigraphic findings in horses with a bone fragility disorder: 16 cases (1980-2006).
Journal of the American Veterinary Medical Association    June 4, 2008   Volume 232, Issue 11 1694-1699 doi: 10.2460/javma.232.11.1694
Anderson JD, Galuppo LD, Barr BC, Puchalski SM, Macdonald MM, Whitcomb MB, Magdesian KG, Stover SM.To describe clinical and scintigraphic abnormalities in horses with a bone fragility disorder. Methods: Retrospective case series. Methods: 16 horses with scintigraphic evidence of multiple sites of increased radiopharmaceutical uptake (IRU). Procedures-Medical records were reviewed for information on signalment; history; clinical, clinicopathologic, and diagnostic imaging findings; and treatment. Follow-up information was obtained through telephone interviews with owners. Results: Horses ranged from 4 to 22 years old; there were 8 castrated males and 8 females. Foci of IRU most commonly invol...
Quantitative morphology of the equine laminar junction in relation to capsule shape in the forehoof of Standardbreds and Thoroughbreds.
Equine veterinary journal    May 20, 2008   Volume 40, Issue 5 473-480 doi: 10.2746/042516408X313652
Thomason JJ, Faramarzi B, Revill A, Sears W.Differences in hoof morphology have largely been underappreciated in the literature until recently, and it is these that hold the key to interpreting functional adaptation in the hoof. Objective: Primary laminar morphology correlates with hoof capsule shape; and breeds with different hoof shapes and loadings show different patterns of correlation. Methods: Seventeen measurements of capsule shape and 3 of primary epidermal laminae (PEL) morphology (spacing, orientation and curvature) were made on right and left front hooves from 27 Standardbred and 25 Thoroughbred horses, and tested for breed d...
The collateral ligaments of the distal interphalangeal joint: magnetic resonance imaging and post mortem observations in 25 lame and 12 control horses.
Equine veterinary journal    May 20, 2008   Volume 40, Issue 6 538-544 doi: 10.2746/042516408X313661
Dyson S, Blunden T, Murray R.Magnetic resonance imaging (MRI) is used with increasing frequency to diagnose injuries of the collateral ligaments (CLs) of the distal interphalangeal (DIP) joint, but the results have not been verified by histology and the mechanism of injury is poorly understood. Objective: Abnormal signal intensity and tissue contour represents change in tissue structure detected on histology. Objective: To compare results in horses free from and those with chronic lameness and to describe possible progression of lesions. Methods: One or both feet of horses free from lameness (Group N: n = 12) and with foo...
Diagnostic imaging of the equine fetlock region using radiography and ultrasonography. Part 2: the bony disorders.
Veterinary journal (London, England : 1997)    May 7, 2008   Volume 181, Issue 2 123-136 doi: 10.1016/j.tvjl.2008.01.017
Vanderperren K, Saunders JH.The metacarpophangeal/metatarsophalangeal (fetlock) joint in the horse is commonly associated with equine lameness and diagnostic imaging is routinely used to investigate disorders of the joint and its surrounding tissues. This review describes the osseous disorders of the fetlock as well as the technical aspects of taking radiographic and ultrasonographic images of the different lesions. In current clinical practice, a combination of radiography and ultrasonography is still the most frequently used approach to arrive at a diagnosis.
[Animal welfare in prevention and therapy of laminitis].
DTW. Deutsche tierarztliche Wochenschrift    May 1, 2008   Volume 115, Issue 3 106-113 
Winkelsett S, Vervuert I.Laminitis is a systemic disease which is manifested as a non infectious condition in the foot. The management of feeding and housing conditions is necessary to treat the endocrinological and metabolic disturbances of laminitic horses. The Equine Metabolic Syndrome (EMS) is predisposing for developing laminitis, and it is characterised by obesity, insulin resistance, hypertension and dyslipidaemia. A genetical predisposition is supposed and EMS is accompanied by a lack of exercise and inadequate energy intake. Laboratory examinations are of great importance for diagnosis. Analyses of insulin, g...
Diagnostic imaging of the equine fetlock region using radiography and ultrasonography. Part 1: Soft tissues.
Veterinary journal (London, England : 1997)    April 28, 2008   Volume 181, Issue 2 111-122 doi: 10.1016/j.tvjl.2008.03.005
Vanderperren K, Saunders JH.The equine fetlock is the joint most commonly associated with lameness. Although the fetlock is regarded as a simple joint, diagnosis of a fetlock disorder can be a challenge and various imaging modalities are routinely used to arrive at an accurate diagnosis. This review describes the principal disorders affecting the soft tissues of the fetlock region and addresses some of the technical aspects involved in taking radiographic and ultrasonographic images of the different soft tissue lesions. A combination of radiography and ultrasonography is still the most commonly used diagnostic approach i...
Effects of topical application of pirfenidone ointment on thermoplasty-induced acute lameness in a double-blind and acute and chronic lameness of musculoskeletal origin in an open multi-centered field trial in horses.
Research communications in molecular pathology and pharmacology    April 23, 2008   Volume 117-118 47-63 
Giri SN, Margolin SB.The effectiveness of pirfenidone ointment against thermoplasty-induced acute foreleg lameness in a double-blind study, and against acute and chronic lameness of musculoskeletal origin in an open multi-centered field trial was evaluated in this study. Thermoplasty was performed on both inner forelegs at designated locations of each horse under anesthetics. A 10% pirfenidone or placebo ointment was topically applied starting 24 hours after the thermoplasty three times daily for 7 days. For acute and chronic lameness of musculoskeletal origin, pirfenidone ointment was also applied one to three ti...
Conservative treatment of a comminuted cervical fracture in a racehorse.
Irish veterinary journal    April 1, 2008   Volume 61, Issue 4 244-247 doi: 10.1186/2046-0481-61-4-244
Vos Nj.The 'classical' or 'Hangman' neck fracture involves the odontoid peg (process) of the second cervical vertebra (C2), and is described as an axial, dens or odontoid peg fracture in both the veterinary and human literature. Possible surgical treatment in both foals and adult horses requires a technique that allows decompression, anatomical alignment and stabilisation of the odontoid fracture. A limited number of surgical cases in foals have been reported in literature, but never in an adult horse. A mature Irish Thoroughbred racehorse was diagnosed with a type 2a odontoid peg fracture. Clinical ...
Suspected primary scapulohumeral osteoarthritis in two Miniature ponies.
Australian veterinary journal    March 28, 2008   Volume 86, Issue 4 153-156 doi: 10.1111/j.1751-0813.2008.00260.x
Parth RA, Svalbe LS, Hazard GH, Church S.Two cases of severe scapulohumeral osteoarthritis in Miniature ponies are described, one bilateral and the other unilateral. The condition is thought to occur in miniature breeds as a result of scapulohumeral dysplasia. The presentation in one of the ponies was unusal: it refused to pick up either fore limb, with progression to a uniquely bizarre gait with narrow forelimb placement, an arched back and widely placed hindlimbs camped well forward under the body. The other pony was presented for an acute unilateral non-weight bearing forelimb lameness. Response to analgesia in both cases was poor...
Retrospective analysis of exploratory laparotomies in 192 Andalusian horses and 276 horses of other breeds.
The Veterinary record    March 11, 2008   Volume 162, Issue 10 303-306 doi: 10.1136/vr.162.10.303
Muñoz E, Argüelles D, Areste L, Miguel LS, Prades M.The medical records of 468 horses that underwent 490 exploratory laparotomies for the correction of gastrointestinal diseases were reviewed to search for differences between Andalusian horses and other breeds. The seasonal distribution of surgical colics and their outcome and complications were also investigated. Bivariant analysis was used to compare the horses' age, gender and breed with the type of surgery, the bowel affected and the type of colic, and all these variables were compared in relation to euthanasia during surgery, complications, short-term survival and seasonal distribution. A ...
Basic farriery for the performance horse.
The Veterinary clinics of North America. Equine practice    March 4, 2008   Volume 24, Issue 1 203-218 doi: 10.1016/j.cveq.2007.12.002
O'Grady SE.Proper farriery promotes a healthy functional foot and biomechanical efficiency and prevents lameness. Because the equine veterinarian is responsible for the soundness of the horse, a working knowledge of farriery becomes essential. A thorough knowledge of traditional horseshoeing enables the veterinarian to interact with the farrier at the farrier's level; this ultimately enhances and promotes quality hoof care. This article focuses on fundamental farriery and recognizing subtle changes in hoof conformation that can be used to preserve the integrity of the hoof capsule, along with the structu...
Adaptation strategies of horses with lameness.
The Veterinary clinics of North America. Equine practice    March 4, 2008   Volume 24, Issue 1 79-100 doi: 10.1016/j.cveq.2007.11.010
Weishaupt MA.The skill to diagnose lameness in horses is paramount for every equine practitioner. Early recognition of locomotor deficiencies plays a central role in sports medicine management, preventing deterioration of the disease or catastrophic injuries. Horses use characteristic compensatory movements of specific body parts to decrease loading of the affected limb. This article describes the underlying changes in intra- and interlimb coordination and the resulting load redistribution between the limbs. This enables the practitioner to better understand the changes in movement associated with lameness...
Plasmid growth hormone releasing hormone therapy in healthy and laminitis-afflicted horses-evaluation and pilot study.
The journal of gene medicine    February 28, 2008   Volume 10, Issue 5 564-574 doi: 10.1002/jgm.1170
Brown PA, Bodles-Brakhop A, Draghia-Akli R.In vivo electroporation dramatically improves the potency of plasmid-mediated therapies, including in large animal models. Laminitis and arthritis are common and debilitating diseases in the horse, as well as humans. Methods: The effects of growth hormone releasing hormone (GHRH) on healthy horses and on horses with laminitis that were followed for 6 months after a single intramuscular injection and electroporation of 2.5 mg of an optimized myogenic GHRH-expressing plasmid were examined. Results: In the first study on six healthy horses, we observed a significant increase in body mass by day 1...
Short term analgesic effect of extracorporeal shock wave therapy in horses with proximal palmar metacarpal/plantar metatarsal pain.
Veterinary journal (London, England : 1997)    February 20, 2008   Volume 179, Issue 1 50-59 doi: 10.1016/j.tvjl.2007.09.020
Imboden I, Waldern NM, Wiestner T, Lischer CJ, Ueltschi G, Weishaupt MA.Extracorporeal shock wave therapy (ESWT) is an accepted form of treatment for chronic cases of proximal suspensory desmitis (PSD). Subjective evaluation of horses shortly after being treated with ESWT has led clinicians to comment on an immediate reduction in lameness. This study aimed to evaluate the analgesic effect of ESWT on 16 horses with PSD or PSD-like pain in a fore- or hindlimb. To objectively assess lameness, gait analysis was performed on an instrumented treadmill before and 6, 24, 48 and 72h after ESWT of the origin of the suspensory ligament and the results compared to the effects...
Autologous platelet concentrates as a treatment for musculoskeletal lesions in five horses.
The Veterinary record    February 19, 2008   Volume 162, Issue 7 208-211 doi: 10.1136/vr.162.7.208
Argüelles D, Carmona JU, Climent F, Muñoz E, Prades M.Two horses with acute tendinopathy of a superficial digital flexor tendon (SDFT) and three horses with chronic proximal desmitis of the suspensory ligament (PDSL) were treated by injecting autologous concentrates of their platelets into the lesions. The lesions were monitored ultrasonographically and clinically. There were significant ultrasonographic and clinical improvements in the two horses with SDFT, but no ultrasonographic improvements in the horses with PDSL; however, they improved clinically and became less lame. All the horses had returned to their pre-injury level of performance by s...
Elbow joint luxation in a 1-month-old foal.
Australian veterinary journal    February 15, 2008   Volume 86, Issue 1-2 56-59 doi: 10.1111/j.1751-0813.2007.00245.x
Rubio-Martínez LM, Vázquez FJ, Romero A, Ormazábal JR.This paper reports on luxation of the elbow joint without concomitant fracture in a 1-month-old foal. Conservative treatment, with closed reduction and full-limb bandaging, including caudal and lateral splints, seemed successful initially, however, failed to provide enough stability and luxation recurred, and open reduction and surgical placement of prosthetic collateral ligaments was required. Luxation of the elbow joint should be considered when acute non-weight bearing forelimb lameness occurs associated with pain and swelling in the area of the elbow in young foals. Closed reduction failed...
Short incomplete sagittal fractures of the proximal phalanx in ten horses not used for racing.
Veterinary surgery : VS    February 7, 2008   Volume 37, Issue 2 193-200 doi: 10.1111/j.1532-950X.2007.00359.x
Kuemmerle JM, Auer JA, Rademacher N, Lischer CJ, Bettschart-Wolfensberger R, Fürst AE.To describe short incomplete sagittal fractures of the proximal phalanx (type Ia P1 fractures) in horses not used for racing and report outcome. Methods: Retrospective study. Methods: Horses (n=10) with type Ia P1 fractures. Methods: Retrieved data of horses with type Ia P1 fractures were signalment, history and results of orthopedic examination. Radiographs were re-evaluated for position and length of the fracture line, presence of osteoarthritis or subchondral cystic lesions (SCL), periosteal new bone formation and subchondral sclerosis. Conservative treatment (n=4) included box confinement ...
Effectiveness of administration of phenylbutazone alone or concurrent administration of phenylbutazone and flunixin meglumine to alleviate lameness in horses.
American journal of veterinary research    February 5, 2008   Volume 69, Issue 2 167-173 doi: 10.2460/ajvr.69.2.167
Keegan KG, Messer NT, Reed SK, Wilson DA, Kramer J.To determine the effectiveness of administering multiple doses of phenylbutazone alone or a combination of phenylbutazone and flunixin meglumine to alleviate lameness in horses. Methods: 29 adult horses with naturally occurring forelimb and hind limb lameness. Methods: Lameness evaluations were performed by use of kinematic evaluation while horses were trotting on a treadmill. Lameness evaluations were performed before and 12 hours after administration of 2 nonsteroidal anti-inflammatory drug (NSAID) treatment regimens. Phenylbutazone paste was administered at approximately 2.2 mg/kg, PO, ever...
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