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Topic:Lameness

Lameness in horses is a condition characterized by an abnormal gait or stance due to pain or mechanical dysfunction affecting the limbs or spine. It is a common issue in equine practice and can result from a variety of causes, including injury, infection, or degenerative diseases. Lameness can affect a horse's performance and quality of life, making accurate diagnosis and management important for equine health. Diagnostic techniques often include physical examination, imaging, and gait analysis. This page aggregates peer-reviewed research studies and scholarly articles that explore the etiology, diagnostic methods, and management strategies for lameness in horses.
Hidden Tarsal Lesions: The Role of Flexed and Oblique Radiographs in Young Horses.
Journal of equine veterinary science    August 28, 2026   106136 doi: 10.1016/j.jevs.2026.106136
Cianci JM, Dobbs EC, Bills KW, Engiles JB, Orsini JA.Radiographically apparent tarsal lesions associated with developmental orthopedic disease and joint sepsis are common in young horses. Standard radiographic projections are routinely used to identify osseous changes but may fail to detect lesions due to superimposition and complex anatomy. This retrospective case series describes plantar trochlear ridge lesions in young horses that were not identified on standard four projection radiograph series but were detected using flexed lateromedial and flexed oblique projections. Cases were selected based on persistent clinical signs localizing to the ...
Walking prior to contrast tenogram radiograph acquisition improves radiological identification of equine digital flexor tendon sheath pathology.
Journal of equine veterinary science    August 25, 2026   106132 doi: 10.1016/j.jevs.2026.106132
Martynski P, Kent A, Bathe A.the protocol for mobilization of the fetlock region prior to acquiring a contrast tenogram radiograph is not clearly defined. Objective: to determine if walking exercise improves identification of DFTS pathology on contrast tenography. Methods: Prospective cohort study. Nineteen horses that underwent contrast tenography and subsequent surgical tenoscopy were included. A tenogram protocol was developed to enable comparison of diagnostic accuracy after increasing mobilization of the affected limb post-injection. Following contrast injection three tenogram radiographs were taken, (1) immediately ...
Multi-Detector Helical Computer Tomography, Transrectal Ultrasonography and Histology of the Lumbosacral Area: A Comparative Study in Warmblood Horse Cadavers.
Animals : an open access journal from MDPI    August 21, 2026   Volume 16, Issue 16 2627 doi: 10.3390/ani16162627
Schmitz T, Mathys RA, Geyer H, Borel N, Hilbe M, Ohlerth SM, Bischofberger A.Pain arising from the lumbosacral region is a recognized cause of poor performance and impaired welfare in horses. However, structural changes in the intertransverse joints (ITJs), lumbar articular process joints (APJs), and lumbosacral intervertebral discs (LSDs) may also occur in asymptomatic horses, complicating interpretation of imaging findings.This study evaluated these structures in 14 middle-aged Warmblood cadavers that were not lame according to the owners prior the onset of the problem that resulted in euthanasia or slaughter and correlated ultrasonographic (US) and computed tomograp...
Quantifying the Equine Pain Response to Paracetamol Administration in Horses With Chronic Lameness Already Receiving Non-Steroidal Anti-Inflammatories.
Veterinary medicine and science    August 13, 2026   Volume 12, Issue 5 e71098 doi: 10.1002/vms3.71098
Conduit S, Bowen M, Bailey J, Redpath A.Paracetamol is used in horses alongside non-steroidal anti-inflammatories (NSAIDs) for multi-modal analgesia; however to date there are few studies published which have investigated its analgesic effect in the horse. Horses were recruited to this study from a population of geriatric horses at The Horse Trust. Horses were selected based on the following inclusion criteria; documented naturally occurring chronic lameness and being treated with an NSAID at the licensed dose and dosing interval. This population was assessed with a five-point subjective lameness grading system performed live by two...
Serum Osteocalcin and CTX-I in Fit-to-Race Thoroughbred Racehorses: Reference Intervals and Associations with Demographic, Training, and Lameness-Related Factors.
Animals : an open access journal from MDPI    August 12, 2026   Volume 16, Issue 16 2514 doi: 10.3390/ani16162514
Tually P, Meadows J, Hathway M, Currie G.Musculoskeletal injury remains a major welfare and performance concern in Thoroughbred racing, and biomarkers for early risk stratification are of scientific interest. This multicentre observational cohort study characterised serum concentrations of two bone turnover markers, osteocalcin/BGLAP (OC) and C-terminal telopeptide of type I collagen (CTX-I), in 1359 fit-to-race Thoroughbred racehorses sampled across New South Wales, Victoria, and Western Australia. Biomarker distributions, population-wide percentile ranges, demographic and training-related associations, and short-term soundness outc...
Pelvic axial rotation in hindlimb lame horses changes after diagnostic analgesia.
Equine veterinary journal    August 10, 2026   doi: 10.1002/evj.70300
Hernlund E, Engell MT, Persson-Sjödin E, Rhodin M, Haubro-Andersen P, Byström A.Visual assessment of mild to moderate hindlimb lameness has low sensitivity and specificity, potentially leading to flawed diagnostic procedures. Pelvic axial rotation (roll) makes the assessment more complex but is also a potential source of information. Objective: To describe pelvic roll patterns in horses with unilateral hindlimb lameness before and after diagnostic analgesia. Methods: Retrospective study. Methods: Optical motion capture data from 20 horses with unilateral hindlimb lameness before and after successful local analgesia (assessed visually and objectively) were retrospectively ...
Musculoskeletal examination of the hind limb of the horse.
Journal of the American Veterinary Medical Association    August 7, 2026   1 doi: 10.2460/javma.26.03.0234
Kamm JL, Odegaard J, Mogannam B.The intention of this tutorial video is to illustrate the methods of examining the hind limb and back of a horse in order to identify abnormalities that may be associated with lameness or disease. Unassigned: An 18-year-old quarter horse stallion was used for examination. Unassigned: The horse was examined for abnormalities using physical examination. Unassigned: The examination of the hind limb and epaxial region of the horse was successfully completed. Unassigned: The techniques described are required to identify abnormalities in the equine hind limb and can be utilized during a lameness exa...
Short-term effects of pulsed electromagnetic field therapy on subjective flexion-associated lameness responses and circulating cytokines in horses with distal tarsal osteoarthritis.
Journal of equine veterinary science    August 5, 2026   106106 doi: 10.1016/j.jevs.2026.106106
Wilson I, Kiger K, Reynolds S, Justice M, Kapadia C, Coleman SJ, Crook RA, Fedorka CE.Pulsed electromagnetic field (PEMF) therapy is commonly used in equine sports medicine for its proposed anti-inflammatory effects; however, limited controlled studies have evaluated its physiologic effects in horses. Objective: The objective of this study was to investigate the effects of PEMF therapy on flexion-induced lameness and circulating cytokines in horses with radiographic evidence of distal tarsal osteoarthritis. Methods: Six mares were enrolled in a repeated-measures crossover design in which each horse served as its own control. Horses were evaluated at baseline (sham PEMF) and at ...
Cryopreserved umbilical allograft (equicenta® CTM) improves clinical outcomes compared with clinician-selected standard of care in performance horses: a pragmatic prospective controlled trial.
Frontiers in veterinary science    August 4, 2026   Volume 13 1833933 doi: 10.3389/fvets.2026.1833933
Bertone AL, Davern AJ, Sutter WW, Mesch H, Beinlich C, Smith A, Ramstrom C, White S, Dubynsky B, Cantrell K, Hay BP, Davis W, Mazzarelli L.This multicenter, prospective, controlled clinical study and client survey evaluated the safety and effectiveness of an equine umbilical tissue suspension (equicenta® CTM; eCTM, 2:1) compared with clinician-selected standard of care (SOC) for treating lame performance horses. Unassigned: This pragmatic, real-world, open-label study enrolled horses diagnosed with appendicular musculoskeletal conditions affecting the joints, tendons, or ligaments under owner consent and an intention-to-treat design with an optional crossover after no improvement at 12 weeks and per-protocol analyses at 26 ...
Core decompression augmented with bone marrow aspirate concentrate for refractory distal sesamoid bone pathology in horses: A retrospective clinical study.
Veterinary surgery : VS    August 1, 2026   doi: 10.1111/vsu.70139
Maleas G, Mageed M, Hargitaiova K.To determine short- and long-term outcomes of core decompression combined with autologous bone marrow aspirate concentrate (BMAC) in treating moderate-to-severe refractory distal sesamoid bone (DSB) trabecular pathology in horses. Methods: Retrospective observational study. Methods: A total of 21 client-owned Warmblood horses with DSB pathology unresponsive to conservative management. Methods: Preoperative diagnosis included lameness localization by diagnostic analgesia and magnetic resonance imaging (MRI) confirmation of DSB trabecular pathology. Horses underwent arthroscopic core decompressi...
A postmortem grading system for articular cartilage loss of the dorsoproximal aspect of the proximal phalanx of Thoroughbred racehorses. Gibson MJ, Dittmer KE, Legg KA, Wehrle-Martinez AS, Beggan CP, Sommerville GO, Rogers CW.The metacarpophalangeal and metatarsophalangeal joints in Thoroughbred racehorses are common injury sites, given their high range of motion and compression during galloping. In New Zealand, the proximal phalanx (P1) is a common site for race-day fracture, but the lesions of this bone have not been described. Therefore, we created a scoring system to describe cartilage on the dorsoproximal aspect of P1 in New Zealand Thoroughbred racehorses. We collected 102 P1s from racehorses submitted for postmortem examination. Horses were categorized into 2 cohorts: 1) fracture (18 horses euthanized becaus...
Equine nuclear medicine: Current state of play.
Seminars in nuclear medicine    July 29, 2026   S0001-2998(26)00143-1 doi: 10.1053/j.semnuclmed.2026.07.004
Tually P, Becker S, Currie GM.Equine nuclear medicine provides functional information on bone turnover, perfusion, inflammation and tracer biodistribution. Its role has evolved from planar scintigraphy toward SPECT, PET and quantitative imaging. This review synthesised the historical foundations and contemporary state of equine nuclear medicine, with emphasis on racehorse and performance-horse applications. Methods: A PRISMA-aligned systematic narrative review and evidence map were undertaken. MEDLINE via PubMed, Web of Science Core Collection and SciQuest were searched, supplemented by reference-list screening, forward ci...
Anatomopathological aspects of osteoarticular lesions associated with Rhodococcus equi infection in two foals.
Veterinary research communications    July 20, 2026   Volume 50, Issue 5 468 doi: 10.1007/s11259-026-11317-x
Pastor FM, Barros SO, Campos LF, de Jesus Nascimento AE, Guimarães GH, de Souza Guimarães Filho CR, Torres LEC, de Lima PA, da Silveira Xavier AB....Rhodococcus equi is an important bacterium that affects foals up to six months of age, especially those that are immunocompromised. The main manifestation is pyogranulomatous pneumonia; nevertheless, extrapulmonary lesions have not only been reported, but are not uncommon, including arthritis and osteomyelitis. Despite the widespread occurrence of rhodococcosis, the macro- and microscopic lesions in the musculoskeletal system are still poorly understood, and a detailed study is needed to better understand the pathogenic potential of the organism. The aim of this report is to present the anatom...
Limited Effects of High-Intensity Laser Therapy on Clinical and Radiographic Outcomes in Three-Year-Old Arabian Racehorses with Dorsal Metacarpal Disease.
Veterinary sciences    July 17, 2026   Volume 13, Issue 7 695 doi: 10.3390/vetsci13070695
Śniegucka K, Soroko-Dubrovina M, Zielińska P, Dudek KD.Dorsal metacarpal disease (DMD) is a common musculoskeletal injury in young racehorses, and effective non-invasive treatments remain of clinical interest. This study aimed to evaluate whether high-intensity laser therapy (HILT), which was applied as the sole intervention in horses retired from training, reduces the clinical signs of DMD compared with untreated controls. During the 2023-2024 racing seasons, 15 Arabian racehorses diagnosed with DMD were enrolled; 9 received HILT and 6 served as controls without laser therapy. The treatment protocol consisted of five daily HILT sessions followed ...
Correlation of Positron Emission Tomography and Low-Field Standing Magnetic Resonance Imaging in Horses With Forelimb Lameness Localized to the Foot. Kelleher ME, Aarsvold S, Anishchenko SI, Gokun Y, Beylin D, Zhu X.Low-field magnetic resonance imaging (LF-MRI) and positron emission tomography (PET) imaging can be obtained in the standing horse. There is potential for increased diagnostic capacity combining PET with MRI, given that PET assesses the metabolic activity of injured tissues, whereas MRI provides structural and functional details on both bone and soft tissue anatomy. This study aimed to describe 18-fluorine-fluorodeoxyglucose (F-FDG)-PET and 18-sodium fluoride (F-NaF)-PET imaging of horses with forelimb lameness localized to the foot and compare PET with LF-MRI. Fourteen horses with lameness lo...
Imaging Diagnosis: Imaging Diagnosis of Lateral Plantar Digital Vein Thrombosis in a Yearling Thoroughbred. Garcia-Collao MR, Sanclemente JL, Larriva DS, Roberts GD, Ragle CA.A 1-year-old thoroughbred filly was referred to the Washington State Veterinary Teaching Hospital with a 4-month history of left hind limb swelling, from the mid metatarsus to the distal pastern, without lameness. Previous imaging (digital radiographs, ultrasound, and low-field magnetic resonance imaging [MRI]) was inconclusive, with a tentative diagnosis of lymphatic drainage impairment. A high-field MRI diagnosed left lateral plantar digital vein thrombosis, with secondary lymphatic dilation and edema. The filly was discharged with rehabilitation instructions and resumed exercise shortly aft...
Gastroscopic Evaluation of Gastric Mucosa in Horses Treated With Flunixin Meglumine or High-Dose Firocoxib: A Descriptive Pilot Study.
Veterinary medicine and science    July 8, 2026   Volume 12, Issue 4 e71061 doi: 10.1002/vms3.71061
de Oliveira RA, Correa ADS, Monteiro FDO, Teixeira PPM.Equine Gastric Ulcer Syndrome (EGUS) is common in horses, and nonsteroidal anti-inflammatory drugs (NSAIDs) are a known risk factor for gastrointestinal ulceration. Although COX-2 selective NSAIDs such as firocoxib theoretically offer a better safety profile, endoscopic evidence for their mucosal safety at high off-label doses is lacking. Objective: To compare the effects of label-dose flunixin meglumine and high-dose firocoxib on the gastric mucosa of a small selected group of horses using serial gastroscopy and histopathology in a descriptive pilot study. Methods: Twenty mixed-breed horses w...
Synovial fluid oxidative stress index as a biomarker for arthritis severity in thoroughbred racehorses.
Research in veterinary science    July 7, 2026   Volume 210 106316 doi: 10.1016/j.rvsc.2026.106316
Tsuzuki N, Tsuchiya T, Tsuihiji T, Kusano K, Kambayashi Y, Takeyama A.Arthritis is a major cause of lameness in racehorses. Even when lameness improves, it may recur after training resumes, making it difficult to determine the disease state and when to end treatment. This retrospective observational study examined whether oxidative stress in synovial fluid could assess arthritis status in racehorses. Synovial fluid samples obtained during routine clinical practice from horses with arthritis and control samples obtained from horses without clinical or radiographic evidence of carpal joint disease were retrospectively analyzed. A total of 72 Thoroughbreds in Japan...
An Investigation of the Role of Ridden Exercise, Including Application of the Ridden Horse Pain Ethogram, in Pre-Purchase Examinations of Sports Horses.
Animals : an open access journal from MDPI    July 7, 2026   Volume 16, Issue 13 2105 doi: 10.3390/ani16132105
Dyson S.Many horses undergo a pre-purchase examination (PPE) prior to acquisition by a new owner; however, despite evidence that lameness and canter dysfunction may only be apparent during ridden exercise, ridden exercises assessing gait quality is not a routine part of PPEs. The objectives were to determine the influence of the results of ridden exercise on decision-making concerning risk assessment for purchase and to establish the long-term performance of horses. Twenty-five sports horses underwent PPEs including ridden exercises to assess gait quality and to apply the Ridden Horse Pain Ethogram (R...
Prevalence and radiographic features of cyst-like lesions in German Warmblood horses presented for pre-purchase examination.
Frontiers in veterinary science    July 6, 2026   Volume 13 1809383 doi: 10.3389/fvets.2026.1809383
Wendling EM, Hellige M, Freise F, Lingens P, Tietje S, Delling U.Cyst-like lesions (CLLs) are frequently detected during radiographic examinations of equine limbs. They may represent a potential risk factor during pre-purchase examination (PPE) and are of considerable clinical and economic importance, as they may lead to negative purchase decisions. While affected horses may develop lameness, incidental findings have also been reported. The goal of the study was to describe the prevalence, location and radiographic characteristics of CLLs in a group of sound German Warmblood horses. Unassigned: A retrospective cohort study was conducted on 3863 German Warmb...
A point-based laminitis risk scoring system and machine learning framework for prediction of laminitis in horses.
Frontiers in veterinary science    July 1, 2026   Volume 13 1809041 doi: 10.3389/fvets.2026.1809041
Abdullah , Bensmail H, Johnson JP, Bouhali O.Laminitis is a painful and potentially life-threatening inflammatory condition of the equine hoof, and its detection remains a major challenge in veterinary practice. Although several risk factors have been reported, the prediction of the onset of laminitis in a subclinical stage using routine clinical data is still limited. This study aims to address this gap by developing an interpretable machine learning (ML) framework for the prediction of the risk of laminitis in horses. A point-based risk scoring system was first constructed using multivariate logistic regression to quantify the contribu...
Straight sesamoidean ligament desmopathy commonly occurs with proximal interphalangeal joint osteoarthritis.
Equine veterinary journal    July 1, 2026   doi: 10.1002/evj.70214
Barton CK, Samol MA, Selberg KT, Goodrich LR.Proximal interphalangeal joint osteoarthritis (PIPJ OA) is a common cause of poor performance in the equine athlete; however, the supporting soft tissue structures surrounding the joint are seldom evaluated. Straight sesamoidean ligament injuries have been previously hypothesised to be concomitant with PIPJ OA; however, the frequency of these lesions coinciding with PIPJ OA has not been fully investigated. Objective: To investigate the prevalence of straight sesamoidean ligament desmopathy (SSLD) in horses presenting with PIPJ OA. Methods: Retrospective clinical study. Methods: Horses presenti...
Comments on ‘Finite element modelling for investigating bone-implant interactions in equine orthopaedics’.
Equine veterinary journal    June 21, 2026   doi: 10.1002/evj.70221
de Souza AF, Meira JBC, Fonteque JH, De Zoppa ALDV.No abstract available
Ulcerative dermatitis, tendinitis, tenosynovitis, and desmitis caused by chronic infection with Serratia odorifera in a racehorse. Schild CO, Moeller R, Yant P, Blea J, Asin J, Henderson E, Nyaoke A, Uzal FA.We investigated a case of severe infection in a racehorse. The horse had developed progressive lameness associated with swelling of the left tarsal region, which progressed to ulcerative dermatitis, tendinitis, tenosynovitis, and desmitis. The plantar side of the superficial digital flexor (SDF) tendon was visible through the skin ulcer, and coalescing nodules were present in the dermis. The horse was euthanized and an autopsy was performed. Grossly, in addition to the changes described above, severe edema of the soft tissues was associated with the ulcer. Microscopically, necrotizing and ulc...
Outcome of keratoma removal using different surgical techniques, including a modified partial hoof wall resection: A retrospective study (2004-2025).
Research in veterinary science    June 21, 2026   Volume 210 106308 doi: 10.1016/j.rvsc.2026.106308
Caballero Delgado G, Grulke S, Evrard L, Sandersen C, de la Rebière de Pouyade G, Salciccia A.Keratomas are diseases of the equine hoof that can be associated with intermittent lameness and/or recurrent foot abscesses. Different surgical techniques for keratoma removal have been described. The aim of this retrospective study was to report the short- and long-term postoperative complications after keratoma removal using different surgical techniques: complete hoof wall resection (CR), partial hoof wall resection (PR) and a modified version of PR (MPR). The medical records of horses diagnosed with keratoma and space occupying lesion (SOL) of the hoof wall (2004-2025) at a Veterinary Teac...
Similar locomotor patterns across Quarter Horse disciplines inform lameness assessment.
Equine veterinary journal    June 12, 2026   doi: 10.1002/evj.70213
de Siqueira RF, Brito LA, de Figueiredo IM, Dos Santos ACR, Dos Anjos LS.Lineage-based selection is central to the Quarter Horse industry and is often justified by the assumption that morphology determines locomotor function. However, objective evidence linking static conformation to discipline-specific locomotor behaviour under standardised conditions remains limited. Objective: To investigate whether morphological differences among Quarter Horse disciplines are associated with distinct locomotor patterns or whether locomotor function converges across disciplines despite morphological variation. Methods: Cross-sectional. Methods: Barrel racing, reining, and ranch ...
Case Report: Oral and topical chronic administration of THC-rich and CBD-rich cannabis oil as palliative care in a rescued horse with open wound, sarcoid and chronic pain.
Frontiers in veterinary science    June 2, 2026   Volume 13 1794084 doi: 10.3389/fvets.2026.1794084
Zamith Cunha R, Kuhn EH, Medeiros JLL, Medeiros GC, Amazonas E.Cannabinoid-based therapies have shown analgesic, anti-inflammatory, and wound-healing potential across veterinary species; however, clinical data on long-term use of THC-rich formulations in horses remain scarce. This case report describes the use of combined oral and topical THC-rich and CBD-rich full-spectrum cannabis oils as part of a palliative care strategy in a rescued horse with severe chronic disease. A senior mixed-breed gelding was rescued with a large, chronic ulcerative lesion of the left hind limb, severe malnutrition, non-weight-bearing lameness (AAEP grade 5/5), and refractory ...
Pilot Study of an Alpha-2-Macroglobulin-Enriched Plasma-Derived Orthobiologic Preparation in Sport Horses with Chronic Degenerative Joint Disease.
Veterinary sciences    May 29, 2026   Volume 13, Issue 6 536 doi: 10.3390/vetsci13060536
Gugliandolo E, Biondi V, De Luca M, Nangano E, Strozzi G, Tosto F, Franco GA, Van Reusel Y, Catone G, Spaas JH.Chronic joint disease is a major cause of lameness and reduced performance in sport horses and is characterized by persistent synovial inflammation and protease-mediated matrix degradation. This exploratory prospective pilot study investigated clinical outcomes and synovial biomarker changes following intra-articular administration of an α-2-macroglobulin plasma-derived preparation. Twenty client-owned sport horses were observed in the treatment group (n = 10) or a comparison group (n = 10) and monitored for up to 180 days under field conditions. Clinical outcomes were assessed longitudinally...
Evaluation of doppler indexes of the lateral palmar digital artery in lame sport horses.
Research in veterinary science    May 27, 2026   Volume 209 106276 doi: 10.1016/j.rvsc.2026.106276
de Chiara M, De Matteis A, Del Prete C, Costanza D, Montano C, Auletta L, Marinelli VG, Buono F, Pasolini MP.Although lateral palmar digital artery (LPDA) flow velocity does not differ between forelimbs, horses with lameness typically reduce loading of the affected limb during the weight-bearing phase. This study aimed to assess whether Pulsed-Wave (PW) Doppler indices of the (LPDA) blood flow differ between the two forelimbs in horses with unilateral forelimb lameness, and whether these differences correlate with lameness severity. Twenty-seven lame and 15 healthy horses were enrolled. All Doppler ultrasonographic examinations were performed by a single operator, blinded to both the presence or abse...
Combined PRP and CCP Therapy Suppresses Inflammation and Protects Cartilage in Post-Traumatic Osteoarthritis.
Veterinary sciences    May 22, 2026   Volume 13, Issue 6 506 doi: 10.3390/vetsci13060506
Ma T, Liu Y, Li Y, Bai H, Liu X, Qiu Z, Ma Y, Li H, Shi B.This study aimed to evaluate the therapeutic effects of platelet-rich plasma (PRP) and Cervus and Cucumis polypeptide (CCP) injections in rats with post-traumatic osteoarthritis (OA). The model was established by transection of the anterior cruciate ligament, and the animals were subsequently treated with PRP and CCP. Articular cartilage degeneration was assessed through gross morphological observation, histopathological staining, and a standardized scoring system. Concurrently, pain-related behaviors, joint swelling, levels of inflammatory cytokines, and markers associated with extracellular ...
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