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Topic:Pain Management

Pain management in horses involves various strategies and interventions designed to alleviate discomfort and improve the well-being of equine patients. It encompasses pharmacological approaches, such as the use of non-steroidal anti-inflammatory drugs (NSAIDs), opioids, and other analgesics, as well as non-pharmacological methods like physical therapy, acupuncture, and environmental modifications. Effective pain management aims to address both acute and chronic pain conditions, which can result from injuries, surgeries, or diseases such as laminitis and arthritis. This page aggregates peer-reviewed research studies and scholarly articles that explore the mechanisms, efficacy, and safety of different pain management techniques in horses, contributing to the understanding and advancement of equine veterinary care.
The use of intrathecal analgesia and contrast radiography as preoperative diagnostic methods for digital flexor tendon sheath pathology.
Equine veterinary journal    May 6, 2012   Volume 45, Issue 1 36-40 doi: 10.1111/j.2042-3306.2012.00573.x
Fiske-Jackson AR, Barker WH, Eliashar E, Foy K, Smith RK.The sensitivity of ultrasonography for the diagnosis of manica flexoria (MF) tears within the digital flexor tendon sheath (DFTS) is lower than for diagnosis of marginal tears of the deep digital flexor tendon (DDFT). Additional diagnostic tools would assist in appropriate decision making for either conservative or surgical management. Objective: To evaluate the improvement in lameness of horses with MF or DDFT tears following intrathecal analgesia and to assess the sensitivity and specificity of contrast radiography for the diagnosis of these tears. Methods: The case records of horses present...
Function of the ramus communicans of the medial and lateral palmar nerves of the horse.
Equine veterinary journal    May 6, 2012   Volume 45, Issue 1 31-35 doi: 10.1111/j.2042-3306.2012.00579.x
Schumacher J, Taintor J, Schumacher J, Degraves F, Schramme M, Wilhite R.The role of the communicating branch between the medial and lateral palmar nerves of horses (i.e. the ramus communicans) in conveying sensory impulses proximally should be determined to avoid errors in interpreting diagnostic anaesthesia of the palmar nerves. Objective: Sensory nerve fibres in the ramus communicans of horses pass proximally from the lateral palmar nerve to merge with the medial palmar nerve, but not vice versa. Objective: To determine the direction of sensory impulses through the ramus communicans between lateral and medial palmar nerves. Methods: Pain in a thoracic foot was c...
Effect of ketamine hydrochloride on the analgesic effects of tramadol hydrochloride in horses with signs of chronic laminitis-associated pain.
American journal of veterinary research    April 27, 2012   Volume 73, Issue 5 610-619 doi: 10.2460/ajvr.73.5.610
Guedes AG, Matthews NS, Hood DM.To investigate the effects of ketamine hydrochloride on the analgesic effects of tramadol hydrochloride in horses with signs of pain associated with naturally occurring chronic laminitis. Methods: 15 client-owned adult horses with chronic laminitis. Methods: Each horse received tramadol alone or tramadol and ketamine in a randomized, crossover study (≥ 2 months between treatments). Tramadol (5 mg/kg) was administered orally every 12 hours for 1 week. When appropriate, ketamine (0.6 mg/kg/h) was administered IV for 6 hours on each of the first 3 days of tramadol administration. Noninvasive sy...
Evaluation of oral administration of firocoxib for the management of musculoskeletal pain and lameness associated with osteoarthritis in horses.
American journal of veterinary research    April 27, 2012   Volume 73, Issue 5 664-671 doi: 10.2460/ajvr.73.5.664
Orsini JA, Ryan WG, Carithers DS, Boston RC.To generate data on the effects of firocoxib administration to horses with osteoarthritis. Methods: Client-owned horses with signs of lameness and joint pain associated with osteoarthritis. Methods: Firocoxib was administered as an oral paste (0.1 mg/kg, q 24 h) for 14 days. Assessments were performed on day 0 (baseline) and days 7 and 14. Results: 390 of 429 horses from 80 sites in 25 states met the criteria for analysis. Quarter Horse and Thoroughbred were the 2 most commonly represented breeds, comprising half of the study population. Signs of musculoskeletal pain or lameness attributed to ...
Short- and long-term results following standing fracture repair in 34 horses.
Equine veterinary journal    April 17, 2012   Volume 44, Issue 6 721-725 doi: 10.1111/j.2042-3306.2012.00569.x
Payne RJ, Compston PC.Standing fracture repair in the horse is a recently described surgical procedure and currently there are few follow-up data. This case series contains 2 novel aspects in the standing horse: repair of incomplete sagittal fractures of the proximal phalanx and medial condylar repair from a lateral aspect. Objective: To describe outcome in a case series of horses that had lower limb fractures repaired under standing sedation at Rossdales Equine Hospital. Methods: Case records for all horses that had a fracture surgically repaired, by one surgeon at Rossdales Equine Hospital, under standing sedatio...
Comparison between magnetic resonance imaging and histological findings in the navicular bone of horses with foot pain.
Equine veterinary journal    April 12, 2012   Volume 44, Issue 6 692-698 doi: 10.1111/j.2042-3306.2012.00565.x
Dyson S, Blunden T, Murray R.There is limited knowledge about both histological features in early navicular disease and what histological features are represented by increased signal intensity in fat-suppressed magnetic resonance (MR) images of the navicular bone. Objective: To characterise increased signal intensity in the spongiosa of the navicular bone in fat-suppressed MR images and to compare this with histopathology; and to compare objective grading of all aspects of the navicular bone on MR images with histological findings. Methods: One or both front feet of 22 horses with foot pain and a median lameness duration ...
Equine laparoscopy: equipment and basic principles.
Compendium (Yardley, PA)    April 11, 2012   Volume 34, Issue 3 E1-E7 
Caron JP.Laparoscopic techniques for veterinary surgery are growing in popularity for the same reason the use of minimally invasive procedures has increased tremendously in human surgery. Compared with open surgery, the benefits of laparoscopic surgery include smaller incisions, reduced postoperative morbidity and pain, shorter hospitalization, a more rapid return to normal activities, and, in some instances, superior access. Laparoscopic surgery is different from open surgery in equipment/instrumentation and psychomotor skills. This first article in a series on equine laparoscopic surgery introduces t...
Diffusion of contrast medium after four different techniques for analgesia of the proximal metacarpal region: an in vivo and in vitro study.
Equine veterinary journal    April 4, 2012   Volume 44, Issue 6 668-673 doi: 10.1111/j.2042-3306.2012.00564.x
Nagy A, Bodó G, Dyson SJ.There is limited information on potential diffusion of local anaesthetic solution after various diagnostic analgesic techniques of the proximal metacarpal region. Objective: To document potential distribution of local anaesthetic solution following 4 techniques used for diagnostic analgesia of the proximal metacarpal region. Methods: Radiodense contrast medium was injected around the lateral palmar or medial and lateral palmar metacarpal nerves in 8 mature horses, using 4 different techniques. Radiographs were obtained 0, 10 and 20 min after injection and were analysed subjectively. A mixture ...
Caudal anaesthesia of the infraorbital nerve for diagnosis of idiopathic headshaking and caudal compression of the infraorbital nerve for its treatment, in 58 horses.
Equine veterinary journal    March 13, 2012   Volume 45, Issue 1 107-110 doi: 10.1111/j.2042-3306.2012.00553.x
Roberts VL, Perkins JD, Skärlina E, Gorvy DA, Tremaine WH, Williams A, McKane SA, White I, Knottenbelt DC.Idiopathic headshaking is often a facial pain syndrome, but a diagnostic protocol has not been described. In a previous study, caudal compression of the infraorbital nerve for treatment offered a fair success rate, but low case numbers and short follow-up time were limitations. Objective: To describe a diagnostic protocol for headshaking, examining the role of bilateral local analgesia of the posterior ethmoidal nerve (PET block). To report longer-term follow-up after surgery of the original cases and further cases and to determine whether changes to the technique influence success rates and c...
Systematic review of efficacy of nutraceuticals to alleviate clinical signs of osteoarthritis.
Journal of veterinary internal medicine    March 9, 2012   Volume 26, Issue 3 448-456 doi: 10.1111/j.1939-1676.2012.00901.x
Vandeweerd JM, Coisnon C, Clegg P, Cambier C, Pierson A, Hontoir F, Saegerman C, Gustin P, Buczinski S.Various treatments of osteoarthritis (OA) have been described, including use of nutraceuticals. Objective: To review systematically the literature about the effects of nutraceuticals on clinical signs of pain or abnormal locomotion in horses, dogs, and cats, and to discuss methodological aspects of trials and systematic reviews. Methods: A systematic search of controlled trials evaluating the impact of nutraceuticals on OA in horses, dogs, and cats was performed, using Medline, CAB Abstracts, and Google Scholar. Scientific evidence was evaluated by means of criteria proposed by the Food and Dr...
Medetomidine continuous rate intravenous infusion in horses in which surgical anaesthesia is maintained with isoflurane and intravenous infusions of lidocaine and ketamine.
Veterinary anaesthesia and analgesia    March 8, 2012   Volume 39, Issue 3 245-255 doi: 10.1111/j.1467-2995.2011.00701.x
Kempchen S, Kuhn M, Spadavecchia C, Levionnois OL.To evaluate medetomidine as a continuous rate infusion (CRI) in horses in which anaesthesia is maintained with isoflurane and CRIs of ketamine and lidocaine. Methods: Prospective, randomized, blinded clinical trial. Methods: Forty horses undergoing elective surgery. Methods: After sedation and induction, anaesthesia was maintained with isoflurane. Mechanical ventilation was employed. All horses received lidocaine (1.5 mg kg(-1) initially, then 2 mg kg(-1) hour(-1)) and ketamine (2 mg kg(-1) hour(-1)), both CRIs reducing to 1.5 mg kg(-1) hour(-1) after 50 minutes. Horses in group MILK received ...
Antinociceptive effects of low dose lumbosacral epidural ropivacaine in healthy ponies.
Veterinary journal (London, England : 1997)    March 6, 2012   Volume 193, Issue 1 240-245 doi: 10.1016/j.tvjl.2011.11.004
van Loon JP, Menke ES, Doornenbal A, Back W, Hellebrekers LJ.The objective of this study was to evaluate the safety and efficacy of low dose lumbosacral epidural ropivacaine in ponies. Antinociceptive effects of epidural ropivacaine were evaluated by means of mechanical nociceptive thresholds (MNTs) at several spinal levels in conscious ponies. The effects of ropivacaine on nociceptive afferent transmission to the spinal cord were also assessed by measuring spinal cord somatosensory evoked potentials (SSEPs) in anaesthetised ponies. Ataxia scores were determined in conscious ponies to assess the effects on motor function. A randomised, placebo controlle...
Standing low-field magnetic resonance imaging in horses with chronic foot pain.
Australian veterinary journal    February 22, 2012   Volume 90, Issue 3 75-83 doi: 10.1111/j.1751-0813.2011.00875.x
Gutierrez-Nibeyro S, Werpy N, White Ii N.Conventional imaging modalities can diagnose the source of foot pain in most cases, but have limitations in some horses, which can be overcome by using magnetic resonance imaging (MRI). However, there are no reports of the MRI appearance and prevalence of foot lesions of a large series of horses with chronic foot lameness. Methods: In the present study, 79 horses with unilateral or bilateral forelimb lameness because of chronic foot pain underwent standing low-field MRI to make a definitive diagnosis. Results: Of the 79 horses, 74 (94%) had alterations in >1 structure in the lame or lamest ...
Analgesic and anti-hyperalgesic effects of epidural morphine in an equine LPS-induced acute synovitis model.
Veterinary journal (London, England : 1997)    February 17, 2012   Volume 193, Issue 2 464-470 doi: 10.1016/j.tvjl.2012.01.015
van Loon JP, Menke ES, L'ami JJ, Jonckheer-Sheehy VS, Back W, René van Weeren P.Epidural morphine is widely used in veterinary medicine, but there is no information about the anti-hyperalgesic and anti-inflammatory effects in acute inflammatory joint disease in horses. The analgesic, anti-hyperalgesic and anti-inflammatory effects of epidural morphine (100mg/animal or 0.17 ± 0.02 mg/kg) were therefore investigated in horses with acute synovitis. In a cross-over study, synovitis was induced in the talocrural joint by intra-articular lipopolysaccharide (LPS). The effect of epidural morphine was evaluated using physiological, kinematic and behavioural variables. Ranges of m...
Clinical evaluation of detomidine-butorphanol-guaifenesin-ketamine as short term TIVA in Spiti ponies.
Pakistan journal of biological sciences : PJBS    January 13, 2012   Volume 14, Issue 11 647-652 doi: 10.3923/pjbs.2011.647.652
Thakur BP, Sharma SK, Sharma A, Kumar A.Veterinarians working under remote field conditions are routinely presented with variety of surgical interventions in equines like castrations, management of wound, traumatic and congenital hernias and musculoskeletal disorders thus necessitating the use of general anaesthesia for management of these conditions. The present study was carried out to evaluate and recommend the suitable short term anaesthetic technique for Spiti ponies under field conditions. Seven clinically healthy male Spiti ponies presented for castration were evaluated for short term Total Intravenous Anaesthesia (TIVA) usin...
Ileal impaction in 245 horses: 1995-2007.
The Canadian veterinary journal = La revue veterinaire canadienne    January 3, 2012   Volume 52, Issue 7 759-763 
Fleming K, Mueller PO.The objective of this study was to identify parameters that would assist in determining the probability of a successful outcome with medical management versus surgical intervention in horses with ileal impaction. Medical records of 245 horses admitted for ileal impaction were reviewed and placed into 2 groups: medical (med) and surgical (sx) treatment. Persistence of abdominal pain, gastric reflux, frequency of analgesic administration, and 1-year survival were evaluated. There were no differences in signalment, abdominal pain, or heart rate among groups; however, significantly more sx horses ...
Sacroiliac injuries in horses.
Compendium (Yardley, PA)    January 1, 2012   Volume 34, Issue 11 E3 
Lorenz J, Brounts SH.This article reviews the pathology, diagnosis, and treatment of sacroiliac joint injuries. These injuries can be acute or chronic and can involve soft tissue structures surrounding the joint or the bony structures of the joint. The several diagnostic modalities for sacroiliac injuries vary in usefulness and accessibility. Treatment of sacroiliac problems is usually supportive and nonspecific and includes the use of antiinflammatory medications and an appropriate exercise regimen. The prognosis depends on the cause, but severe injuries can limit a horse's future athletic activity.
[Traumatology and sport injuries in professional and amateur show-jumping competitors].
Sportverletzung Sportschaden : Organ der Gesellschaft fur Orthopadisch-Traumatologische Sportmedizin    December 12, 2011   Volume 25, Issue 4 222-226 doi: 10.1055/s-0031-1273483
Lechler P, Walt L, Grifka J, Waltl V, Renkawitz T.The objective of this study was to investigate the frequency, extent, and effective preventive measures of sport injuries in professional and amateur-show jumping competitors. In a retrospective study design, 264 show-jumping riders (105 professionals, 159 amateurs) were interviewed by means of a standardised questionnaire. In total, 636 injuries were reported in detail. Injuries were categorised into severity grade I (36.0 %) (not requiring medical attention), grade II (34.6 %) (single medical treatment), grade III (20.9 %) (several outpatient medical treatments) and grade IV (8.5 %) (req...
Phenylbutazone and flunixin meglumine used singly or in combination in experimental lameness in horses.
Equine veterinary journal. Supplement    December 7, 2011   Issue 40 12-17 doi: 10.1111/j.2042-3306.2011.00485.x
Foreman JH, Ruemmler R.Using an adjustable heart bar shoe model of foot pain, the objective of this study was to test the hypothesis that the combined use of phenylbutazone (PBZ) and flunixin meglumine (FM) would prove more efficacious in alleviating lameness than either drug alone. Methods: One hour after induction of lameness at weekly intervals, 8 healthy adult Thoroughbred horses randomly underwent one of 4 i.v. treatments: saline (SAL) placebo (1 ml/45 kg bwt), PBZ (4.4 mg/kg bwt), FM (1.1 mg/kg bwt) or PBZ+FM (at the same dosages as given individually). Heart rate (HR) and lameness score (LS) responses were as...
[Use of local anaesthetics in the horse. Pharmacological and legal aspects].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    December 6, 2011   Volume 39, Issue 2 117-123 
Kästner S.No abstract available
Intra-abdominal hyaluronan concentration in peritoneal fluid of horses with sudden signs of severe abdominal pain.
American journal of veterinary research    December 1, 2011   Volume 72, Issue 12 1666-1673 doi: 10.2460/ajvr.72.12.1666
Lillich JD, Ray-Miller W, Silver KS, Davis EG, Schultz BD.To determine hyaluronan concentrations in peritoneal fluid from healthy horses and horses with sudden signs of severe abdominal pain and to identify the cellular sources of hyaluronan within the peritoneal cavity. Methods: 7 client-owned horses that were evaluated for sudden signs of severe abdominal pain, 6 healthy teaching horses, and 13 euthanized horses (11 with no abdominal disease and 2 that had undergone abdominal surgery 2 weeks previously for a different study). Methods: Abdominal fluid was collected from the client-owned and teaching horses. Hyaluronan concentrations were determined ...
Lesions of the equine neck resulting in lameness or poor performance.
The Veterinary clinics of North America. Equine practice    November 22, 2011   Volume 27, Issue 3 417-437 doi: 10.1016/j.cveq.2011.08.005
Dyson SJ.Lesions of the neck are an uncommon primary cause of pain resulting in either lameness or poor performance but should be considered if local analgesic techniques of the limbs fail to abolish lameness or if there are clinical signs directly referable to the neck such as pain, abnormal neck posture, stiffness, or patchy sweating. Accurate diagnosis requires careful clinical examination, exclusion of other causes of lameness or poor performance, and accurate interpretation of diagnostic imaging findings.
Pain recognition and treatment in the horse: a survey of equine veterinarians in The Netherlands and Belgium.
Tijdschrift voor diergeneeskunde    October 27, 2011   Volume 136, Issue 10 715-724 
Dujardin CL, van Loon JP.This survey investigated the attitudes of equine veterinarians in The Netherlands and the Flemish region of Belgium towards pain management in the horse. Questionnaires were sent out to 771 equine veterinarians, all members of the Dutch or Flemish equine practitioners society. The return rate of completed questionnaires was 16.6%. The survey provided information about the use of analgesic drugs, factors influencing their prescription, pain scoring, analgesic therapy for specific clinical conditions, use of epidural analgesia, and appraisal of personal knowledge of pain management. The pain sco...
Clinical snapshot: acute colic in a paint horse.
Compendium (Yardley, PA)    October 1, 2011   Volume 33, Issue 10 E1-E2 
Stern A.No abstract available
Comparison of transvaginal natural orifice transluminal endoscopic surgery (NOTES®) and laparoscopy for elective bilateral ovariectomy in standing mares.
Veterinary surgery : VS    September 23, 2011   Volume 40, Issue 8 998-1008 doi: 10.1111/j.1532-950X.2011.00877.x
Pader K, Freeman LJ, Constable PD, Wu CC, Snyder PW, Lescun TB.To compare surgical trauma, perioperative pain, surgical time, and complication rate in mares undergoing standing bilateral ovariectomy by natural orifice transluminal endoscopic surgery (NOTES) or laparoscopy. Methods: Experimental study. Methods: Healthy mares (n = 12). Methods: Ovariectomy was performed with a vessel-sealing device by transvaginal NOTES (n = 6) using a flexible endoscope and specialized instruments or by bilateral flank laparoscopy (n = 6). Preoperative and postoperative complete blood count (CBC), plasma fibrinogen concentration, serum amyloid A concentration, peritoneal n...
Physiological and behavioural responses of young horses to hot iron branding and microchip implantation.
Veterinary journal (London, England : 1997)    September 13, 2011   Volume 191, Issue 2 171-175 doi: 10.1016/j.tvjl.2011.08.008
Erber R, Wulf M, Becker-Birck M, Kaps S, Aurich JE, Möstl E, Aurich C.Branding is the traditional and well-established method used to mark horses, but recently microchip transponders for implantation have become available. In this study, behaviour, physiological stress variables and skin temperature in foals were determined in response to hot-iron branding (n=7) and microchip implantation (n=7). Salivary cortisol concentrations increased in response to branding (1.8 ± 0.2 ng/mL) and microchip implantation (1.4 ± 0.1ng/mL), but cortisol release over time did not differ. In response to both manipulations there was a transient increase in heart rate (P<0.001) ...
Comparison of xylazine-butorphanol and xylazine-morphine-ketamine infusions in horses undergoing a standing surgery.
The Veterinary record    September 6, 2011   Volume 169, Issue 14 364 doi: 10.1136/vr.d5333
Benredouane K, Ringer SK, Fourel I, Lepage OM, Portier KG, Bettschart-Wolfensberger R.No abstract available
Treating navicular syndrome in equine patients.
Compendium (Yardley, PA)    September 2, 2011   Volume 33, Issue 1 E2 
Waguespack RW, Hanson RR.Navicular syndrome is a chronic, progressive condition affecting the navicular bone and bursa, deep digital flexor tendon (DDFT), and associated soft tissue structures composing the navicular apparatus. The treatment options for navicular syndrome are as varied as the proposed causes of the condition. The severity of clinical signs, intended use and workload of the horse, and owner compliance with therapy are important considerations in developing a treatment plan. Nonsurgical treatment of navicular syndrome consists of rest, hoof balance and corrective trimming/shoeing, and medical therapy, i...
Close, impinging and overriding spinous processes in the thoracolumbar spine: the relationship between radiological and scintigraphic findings and clinical signs.
Equine veterinary journal    September 1, 2011   Volume 44, Issue 2 178-184 doi: 10.1111/j.2042-3306.2011.00373.x
Zimmerman M, Dyson S, Murray R.There has been no objective study comparing radiological features of spinous processes (SPs) in the thoracolumbar region and/or scintigraphic findings with clinical signs. Objective: To investigate the relationship between the presence or absence of clinical signs of back pain and: 1) radiological findings of close, impinging or overriding SPs; 2) increased radiopharmaceutical uptake (IRU) in the SPs; and 3) the combination of radiological findings and IRU. Also to determine the prevalence of concurrent osseous pathology. Methods: Five-hundred and eighty-two horses, presented for perceived bac...
A randomised, double-blinded, placebo-controlled study on the efficacy of a unique extract of green-lipped mussel (Perna canaliculus) in horses with chronic fetlock lameness attributed to osteoarthritis.
Equine veterinary journal    September 1, 2011   Volume 44, Issue 4 393-398 doi: 10.1111/j.2042-3306.2011.00455.x
Cayzer J, Hedderley D, Gray S.Lyophilised products from green-lipped mussel (Perna canaliculus[LPPC]) are used to orally treat horses with osteoarthritis (OA). However, no randomised, controlled or double-blinded studies on the efficacy of this treatment in horses have been reported to date. Objective: To investigate the effects of a unique LPPC (Biolane)(1) in improving clinical signs of OA in the fetlock. Methods: Data were analysed from 26 horses with primary fetlock lameness in a controlled, randomised and double-blinded, multi-centre clinical trial. The study design was a partial crossover with a washout period and co...
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