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Topic:Public Health

The topic of Public Health and horses encompasses the study of interactions between equine populations and human health systems. It involves examining the transmission of zoonotic diseases, which are diseases that can be transferred between animals and humans, as well as the role of horses in the epidemiology of such diseases. This field also considers the impact of equine-related activities on public health, including injuries and environmental effects. Research in this area often explores preventive measures, management strategies, and policies to mitigate health risks associated with horses. This page compiles peer-reviewed research studies and scholarly articles that investigate the intersection of equine and public health, focusing on disease transmission, risk assessment, and health management strategies.
Evolution of multidrug-resistant Staphylococcus aureus infections in horses and colonized personnel in an equine clinic between 2005 and 2010.
Microbial drug resistance (Larchmont, N.Y.)    August 31, 2011   Volume 17, Issue 3 471-478 doi: 10.1089/mdr.2010.0188
Sieber S, Gerber V, Jandova V, Rossano A, Evison JM, Perreten V.A total of 70 Staphylococcus aureus isolates from postoperative infections in hospitalized horses were isolated between January 2005 and January 2011. Among them, 12 isolates were methicillin-susceptible S. aureus (MSSA), 18 were borderline-oxacillin-resistant S. aureus (BORSA), and 40 were methicillin-resistant S. aureus (MRSA). During the same period, the equine clinic personnel were screened for nasal carriage of BORSA and MRSA. Genotyping revealed that BORSA ST1(MLST)-t2863(spa) isolates were responsible for most equine infections and were the main isolates found in colonized members of th...
Detection of various performance enhancing substances in specimens collected from race horses in Illinois: a five-year experience.
Journal of analytical toxicology    August 30, 2011   Volume 35, Issue 7 438-443 doi: 10.1093/anatox/35.7.438
Taddei L, Benoit M, Sukta A, Peterson J, Gaensslen RE, Negrusz A.In order to protect the integrity of horse racing in Illinois, a complex testing of urine and blood specimens collected post-race from winning and special designation horses is continuously conducted. The initial screening by immunoassays was followed by the confirmation on presumptive positive samples. Instrumental screening was also conducted. Perimortem and postmortem specimens and special exhibits (syringes, needles, etc.) were also analyzed. The administration of alkalinizing agents was detected by measuring the total plasma carbon dioxide concentration. The laboratory analyzed specimens ...
The regulation of veterinary regenerative medicine and the potential impact of such regulation on clinicians and firms commercializing these treatments.
The Veterinary clinics of North America. Equine practice    August 30, 2011   Volume 27, Issue 2 383-391 doi: 10.1016/j.cveq.2011.06.002
Nobert KM.This article provides an overview of the US Food and Drug Administration's current and potential regulation of veterinary regenerative medicine and the various products used in the practice. This article also discusses several of the potential enforcement risks associated with the commercialization of such therapies and products and offers the reader strategies for mitigating those risks. Finally, the article concludes with a review of an important and ongoing court battle that focuses on the marketing and promotion of cellular-based therapies for humans that could have a significant impact on...
Streptococcus equi subspecies equi infection (strangles) in horses.
Compendium (Yardley, PA)    August 27, 2011   Volume 33, Issue 3 E1-E8 
Boyle A.Streptococcus equi subspecies equi (strangles) is a highly contagious upper respiratory infection in horses. The infection is transmitted by inhalation or direct contact with mucopurulent discharge from an infective animal, resulting in fever, depression, and submandibular and retropharyngeal lymph node enlargement that can lead to respiratory distress. Complications include purpura hemorrhagica and metastatic abscessation. Control of outbreaks requires strict isolation protocols and hygiene measures. Detection of carriers is essential for preventing disease recurrence on a farm.
The steroid catabolic pathway of the intracellular pathogen Rhodococcus equi is important for pathogenesis and a target for vaccine development.
PLoS pathogens    August 25, 2011   Volume 7, Issue 8 e1002181 doi: 10.1371/journal.ppat.1002181
van der Geize R, Grommen AW, Hessels GI, Jacobs AA, Dijkhuizen L.Rhodococcus equi causes fatal pyogranulomatous pneumonia in foals and immunocompromised animals and humans. Despite its importance, there is currently no effective vaccine against the disease. The actinobacteria R. equi and the human pathogen Mycobacterium tuberculosis are related, and both cause pulmonary diseases. Recently, we have shown that essential steps in the cholesterol catabolic pathway are involved in the pathogenicity of M. tuberculosis. Bioinformatic analysis revealed the presence of a similar cholesterol catabolic gene cluster in R. equi. Orthologs of predicted M. tuberculosis vi...
Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 2: Risk factors for faecal carriage of antimicrobial-resistant Escherichia coli in horses.
Equine veterinary journal    August 18, 2011   Volume 44, Issue 3 297-303 doi: 10.1111/j.2042-3306.2011.00440.x
Maddox TW, Pinchbeck GL, Clegg PD, Wedley AL, Dawson S, Williams NJ.The increasing prevalence of antimicrobial resistant bacteria such as antimicrobial-resistant and extended spectrum β-lactamase (ESBL)-producing Escherichia coli represents a significant problem for human and veterinary medicine. Despite this, the risk factors for faecal carriage of such bacteria by horses in the UK, particularly those in the wider community, have not been well described. Objective: To characterise the risk factors for faecal carriage of antimicrobial-resistant E. coli amongst horses in the mainland UK. Methods: A cross-sectional study of horses recruited by 65 randomly selec...
Cross-sectional study of antimicrobial-resistant bacteria in horses. Part 1: Prevalence of antimicrobial-resistant Escherichia coli and methicillin-resistant Staphylococcus aureus.
Equine veterinary journal    August 18, 2011   Volume 44, Issue 3 289-296 doi: 10.1111/j.2042-3306.2011.00441.x
Maddox TW, Clegg PD, Diggle PJ, Wedley AL, Dawson S, Pinchbeck GL, Williams NJ.The increasing prevalence of antimicrobial-resistant bacteria such as methicillin-resistant Staphylococcus aureus (MRSA) and antimicrobial-resistant Escherichia coli represents a significant problem. However, the carriage of such bacteria by horses in the UK has not been well characterised. Objective: To estimate the prevalence of nasal carriage of MRSA and faecal carriage of antimicrobial-resistant E. coli amongst horses in the general equine community of the mainland UK. Methods: A cross-sectional study of horses recruited by 65 randomly selected equine veterinary practices was conducted, wi...
The first five days: field and laboratory investigations during the early stages of the equine influenza outbreak in Australia, 2007.
Australian veterinary journal    August 17, 2011   Volume 89 Suppl 1 6-10 doi: 10.1111/j.1751-0813.2011.00724.x
Kirkland PD, Davis RJ, Wong D, Ryan D, Hart K, Corney B, Hewitson G, Cooper K, Biddle A, Eastwood S, Slattery S, Rayward D, Evers M, Wright T....Until August 2007, Australia was one of only three countries internationally recognised to be free of equine influenza (EI). This report documents the diagnosis of the first cases of EI in Australian horses and summarises the investigations that took place over the next 5 days. During that time, a multifocal outbreak was identified across eastern New South Wales and south-eastern Queensland. The use of an influenza type A pan-reactive real-time reverse transcription polymerase chain reaction allowed rapid confirmation of suspect cases of EI.
Hygiene practices to prevent the spread of equine influenza by humans.
Australian veterinary journal    August 17, 2011   Volume 89 Suppl 1 124-125 doi: 10.1111/j.1751-0813.2011.00765.x
Major DA.This paper describes a protocol for hygiene practices that was devised by a practice in which all veterinarians were involved on a daily basis in visiting infected premises, including sampling, treatment of clinical cases and general veterinary work. This protocol was strictly followed when attending an infected or at risk property.
Equine influenza in Australia: a clinical overview.
Australian veterinary journal    August 17, 2011   Volume 89 Suppl 1 11-13 doi: 10.1111/j.1751-0813.2011.00725.x
Gilkerson JR.The clinical symptoms observed during the 2007 equine influenza outbreak are compared and contrasted with those observed in overseas outbreaks and described in the veterinary literature.
Spatial association and clinical development of equine influenza in horses yarded overnight at an equestrian event at Maitland prior to propagating the 2007 epidemic in Australia.
Australian veterinary journal    August 17, 2011   Volume 89 Suppl 1 68-69 doi: 10.1111/j.1751-0813.2011.00751.x
Britton AL, Major DA, Perry GH, Read AJ.The interaction and stabling of horses at equine events may have a substantial impact on the spread of a zoonotic disease. This study aimed to investigate the spread of equine influenza (EI) at an equestrian event at the start of the Australian outbreak. Around one-third of the competing horses were stabled overnight at the event and, of these, 70% developed symptoms of EI within 7 days. The index case was never positively identified, but stabling position and disease onset provided clues to its potential identity.
Enzyme-linked immunosorbent assays for the detection of equine antibodies specific to a recombinant Fasciola hepatica surface antigen in an endemic area.
Parasitology research    August 17, 2011   Volume 110, Issue 2 1001-1007 doi: 10.1007/s00436-011-2587-x
Arias MS, Piñeiro P, Hillyer GV, Francisco I, Cazapal-Monteiro CF, Suárez JL, Morrondo P, Sánchez-Andrade R, Paz-Silva A.The utility of an enzyme-linked immunosorbent assay to determine the sensitization against the trematode Fasciola hepatica in horses from an endemic area (NW Spain) was assessed. Blood samples were collected from 536 horses and tested against a 2.9-kDa recombinant surface protein (FhrAPS) to estimate the presence of IgG antibodies. Data were analysed regarding several intrinsic (age, gender and breed) and extrinsic factors (aptitude and housing). The farm size (number of horses/farm) was also considered. Sixty percent (95% CI 56, 64) of the horses were positive to the FhrAPS-ELISA, with a sign...
Prevention of facial injuries in unmounted equestrians.
The British journal of oral & maxillofacial surgery    August 16, 2011   Volume 49, Issue 8 674 doi: 10.1016/j.bjoms.2011.07.017
Cousin GC.No abstract available
Seasonal dynamics of biting midges (Diptera: Ceratopogonidae: Culicoides), the potential vectors of bluetongue virus, in Sweden.
Veterinary parasitology    August 16, 2011   Volume 184, Issue 1 59-67 doi: 10.1016/j.vetpar.2011.08.009
Ander M, Meiswinkel R, Chirico J.The outbreak of bluetongue (BT) in northern Europe 2006 initiated the monitoring of vectors, biting midges of the genus Culicoides in Sweden. In order to determine the diversity, distribution and seasonal dynamics of Culicoides, weekly collections were made during 2008 and during March-December 2009 using the Ondestepoort Veterinary Institute black light trap. Twenty sampling sites were selected in 12 provinces. In total of 30,704 Culicoides were collected in 2008 and 32,252 in 2009. The most abundant species were the potential vectors of BTV Culicoides obsoletus/C. scoticus that comprised of ...
Hendra vaccine success announced.
Australian veterinary journal    August 13, 2011   Volume 89, Issue 7 N2-N3 doi: 10.1111/j.1751-0813.2011.news_v89_i7.x
Balzer M.No abstract available
Occurrence of fumonisins in feed for swine and horses.
Revista iberoamericana de micologia    August 11, 2011   Volume 29, Issue 3 175-177 doi: 10.1016/j.riam.2011.07.005
Martins HM, Almeida IF, Camacho CR, Santos SM, Costa JM, Bernardo FM.Fumonisin B1 (FB1), fumonisin B2 (FB2), and overall mycotoxins feed contamination may cause several effects on crops production and animal health. The contamination occurred predominantly in corn and corn-based foods and feeds. Objective: This survey intends to provide the occurrence of fumonisins in swine and equine mixed feeds in Portugal, making an overview from 2007 to 2010. Methods: A total of 363 samples were analyzed, 258 from swine feed and 105 from horse feed with HPLC method. The detection limit was 50 μg/kg for FB1 and 100 μg/kg for FB2. Results: The overall results were 13% of FB...
Prevalence of equine herpesvirus type 1 strains of neuropathogenic genotype in a major breeding area of Japan.
The Journal of veterinary medical science    August 9, 2011   Volume 73, Issue 12 1663-1667 doi: 10.1292/jvms.11-0140
Tsujimura K, Oyama T, Katayama Y, Muranaka M, Bannai H, Nemoto M, Yamanaka T, Kondo T, Kato M, Matsumura T.A single non-synonymous nucleotide substitution of guanine (G) for adenine (A) at position 2254 in the viral DNA polymerase gene (encoded by open reading frame [ORF] 30) of equine herpesvirus type 1 (EHV-1) has been significantly associated with neuropathogenic potential in strains of this virus. To estimate the prevalence of EHV-1 strains with the neuropathogenic genotype (ORF30 G(2254)) in the Hidaka district--a major horse breeding area in Japan--we analyzed the ORF30 genomic region in cases of EHV-1 infection in this area during the years 2001-2010. Of the 113 cases analyzed, 3 (2.7%) were...
Transmission and control of African horse sickness in The Netherlands: a model analysis.
PloS one    August 5, 2011   Volume 6, Issue 8 e23066 doi: 10.1371/journal.pone.0023066
Backer JA, Nodelijk G.African horse sickness (AHS) is an equine viral disease that is spread by Culicoides spp. Since the closely related disease bluetongue established itself in The Netherlands in 2006, AHS is considered a potential threat for the Dutch horse population. A vector-host model that incorporates the current knowledge of the infection biology is used to explore the effect of different parameters on whether and how the disease will spread, and to assess the effect of control measures. The time of introduction is an important determinant whether and how the disease will spread, depending on temperature a...
The 2007 outbreak of equine influenza in Australia: lessons learned for international trade in horses.
Revue scientifique et technique (International Office of Epizootics)    August 4, 2011   Volume 30, Issue 1 87-93 doi: 10.20506/rst.30.1.2021
Watson J, Daniels P, Kirkland P, Carroll A, Jeggo M.In August 2007 Australia experienced its first outbreak of equine influenza. The disease occurred first in a quarantine station for imported horses near Sydney and subsequently escaped into the general horse population. After an extensive campaign the disease was eradicated and Australia is again recognised as free of this disease. Equine influenza was then, and is now, recognised to be the major disease risk associated with live horse imports into Australia and measures designed to mitigate this risk formed the basis of the quarantine protocols then in place. Subsequent investigations into th...
Fatal neurologic disease and abortion in mare infected with lineage 1 West Nile virus, South Africa.
Emerging infectious diseases    August 2, 2011   Volume 17, Issue 8 1534-1536 doi: 10.3201/eid1708.101794
Venter M, Human S, van Niekerk S, Williams J, van Eeden C, Freeman F.In 2010, lineage 1 West Nile virus was detected in South Africa in the brain of a pregnant mare that succumbed to neurologic disease and in her aborted fetus, suggesting an association with abortion in horses. All West Nile virus strains previously detected in horses and humans in South Africa were lineage 2.
Endovascular aortic stent graft infection with Streptococcus equi: the first documented case.
Vascular    July 29, 2011   Volume 21, Issue 1 14-16 doi: 10.1258/vasc.2010.cr0258
Parmar J, Winterbottom A, Cooke F, Lever AM, Gaunt M.Streptococcus equi is a common equine infectious disease, but transmission to man is rare and confined to those who commonly come into close contact with horses. Similarly, prosthetic stent graft infection is a rare complication of endovascular aortic aneurysm repair. We describe the first reported case of aortic stent graft with S. equi occurring in a professional racehorse trainer. Clinical presentation, investigations, imaging and management of this case are described. In conclusion, clinicians should consider infection with rare organisms in patients with prosthetic implants who regularly ...
Hendra virus: what do we know?
New South Wales public health bulletin    July 26, 2011   Volume 22, Issue 5-6 118-122 doi: 10.1071/NB10077
Hess IM, Massey PD, Walker B, Middleton DJ, Wright TM.Hendra virus infection is an emerging infectious disease that is not well understood. Most cases of Hendra virus infection have occurred in Queensland, with one case in a horse in NSW. Hendra virus infection has a high mortality rate in horses and humans and as cases could occur anywhere in Australia it is important to be ready for prompt action should an outbreak occur in NSW. This paper: reviews the current knowledge on Hendra virus infection including methods for preventing the disease; explains the animal health and human health response for an outbreak within NSW; and discusses possible f...
Solid-state anaerobic digestion of spent wheat straw from horse stall.
Bioresource technology    July 26, 2011   Volume 102, Issue 20 9432-9437 doi: 10.1016/j.biortech.2011.07.062
Cui Z, Shi J, Li Y.The spent wheat straw from horse stall bedding has lower cellulose and hemicellulose contents, but higher volatile fatty acid content than raw wheat straw. Biogas production from solid-state anaerobic digestion (SS-AD) of spent wheat straw and raw wheat straw was compared in this study. The SS-AD tests were conducted at 22% total solids (TS) content using inoculum from a liquid AD system at three feedstock-to-inoculum (F/I) ratios of 2.0, 4.0, and 6.0. Daily methane yields of spent wheat straw peaked 8 and 3 days earlier than those of raw wheat straw at F/I ratios of 2.0 and 4.0, respectively....
The mosquito Aedes (Aedimorphus) vexans arabiensis as a probable vector bridging the West Nile virus between birds and horses in Barkedji (Ferlo, Senegal).
Medical and veterinary entomology    July 25, 2011   Volume 26, Issue 1 106-111 doi: 10.1111/j.1365-2915.2011.00974.x
Fall AG, Diaïté A, Etter E, Bouyer J, Ndiaye TD, Konaté L.Active catches of adult females of Aedes vexans arabiensis Patton, (Diptera: Culicidae) Patton by nets or aspirator, were conducted in 2003 and 2004 in the vegetation at the edge of temporary ponds in Barkedji, Senegalese Ferlo area. Two hundred and forty-one engorged females were captured, dissected and the gut content adsorbed on a Whatman filter paper and analysed using the enzyme-linked immunosorbent assay (ELISA) technique to determinate the bloodmeal origin. Results indicated that Ae v. arabiensis fed primarily on mammals, including horses (35.7% of the bloodmeals), but also on birds (10...
Natural Burkholderia mallei infection in Dromedary, Bahrain.
Emerging infectious diseases    July 19, 2011   Volume 17, Issue 7 1277-1279 doi: 10.3201/eid1707.110222
Wernery U, Wernery R, Joseph M, Al-Salloom F, Johnson B, Kinne J, Jose S, Jose S, Tappendorf B, Hornstra H, Scholz HC.We confirm a natural infection of dromedaries with glanders. Multilocus variable number tandem repeat analysis of a Burkholderia mallei strain isolated from a diseased dromedary in Bahrain revealed close genetic proximity to strain Dubai 7, which caused an outbreak of glanders in horses in the United Arab Emirates in 2004.
Suspected horse-to-human transmission of MRSA ST398.
Emerging infectious diseases    July 14, 2011   Volume 17, Issue 6 1137-1139 doi: 10.3201/eid/1706.101330
van Duijkeren E, Ten Horn L, Wagenaar JA, de Bruijn M, Laarhoven L, Verstappen K, de Weerd W, Meessen N, Duim B.No abstract available
Phylogenetic and molecular characterization of equine H3N8 influenza viruses from Greece (2003 and 2007): evidence for reassortment between evolutionary lineages.
Virology journal    July 14, 2011   Volume 8 350 doi: 10.1186/1743-422X-8-350
Bountouri M, Fragkiadaki E, Ntafis V, Kanellos T, Xylouri E.For first time in Greece equine influenza virus infection was confirmed, by isolation and molecular analysis, as the cause of clinical respiratory disease among unvaccinated horses during 2003 and 2007 outbreaks. Methods: Equine influenza virus (EIV) H3N8 was isolated in MDCK cells from 30 nasal swabs from horses with acute respiratory disease, which were tested positive by Directigen Flu A. Isolation was confirmed by haemagglutination assay and RT-PCR assay of the M, HA and NA gene. Results: HA sequences of the Greek isolates appeared to be more closely related to viruses isolated in early 19...
Faecal shedding of CTX-M-producing Escherichia coli in horses receiving broad-spectrum antimicrobial prophylaxis after hospital admission.
Veterinary microbiology    July 14, 2011   Volume 154, Issue 3-4 298-304 doi: 10.1016/j.vetmic.2011.07.005
Damborg P, Marskar P, Baptiste KE, Guardabassi L.The objective of this longitudinal study was to investigate the occurrence and genetic background of faecal Escherichia coli resistant to cefotaxime (CTX) in horses receiving broad-spectrum antimicrobial prophylaxis after admission to a veterinary teaching hospital. The ten horses enrolled in the study were treated with cefquinome either alone (n=4) or in combination with metronidazole (n=3) or other antimicrobial agents (n=3). CTX-resistant coliforms in faeces collected before, during and after treatment were quantified on selective MacConkey agar supplemented with CTX, and a colony isolated ...
Use of a recombinant burkholderia intracellular motility a protein for immunodiagnosis of glanders.
Clinical and vaccine immunology : CVI    July 13, 2011   Volume 18, Issue 9 1456-1461 doi: 10.1128/CVI.05185-11
Kumar S, Malik P, Verma SK, Pal V, Gautam V, Mukhopadhyay C, Rai GP.Glanders, caused by the Gram-negative, nonmotile bacterium Burkholderia mallei, is a contagious and highly fatal disease of equines. During the last decade, the number of glanders outbreaks has increased steadily. The disease also has high zoonotic significance and B. mallei is listed biological warfare agent. The complement fixation test (CFT) is a routinely used and internationally recognized test to screen equine sera for the glanders. However, discrepant results have been observed using the CFT. The low sensitivity and specificity of the CFT and enzyme-linked immunosorbent assay (ELISA) ha...
Equine road user safety: public attitudes, understandings and beliefs from a qualitative study in the United Kingdom.
Accident; analysis and prevention    July 13, 2011   Volume 43, Issue 6 2173-2181 doi: 10.1016/j.aap.2011.06.009
Chapman C, Musselwhite CBA.Horse riders represent a significant group of vulnerable road user and are involved in a number of accidents and near misses on the road. Despite this horse riders have received little attention both in terms of academic research and transport policy. Based on literature on vulnerable road user safety, including attitudes to road user safety and behaviour of drivers and their relationship with cyclists and motorcyclists, this paper examines the attitudes and reported behaviour of drivers and horse riders. A total of 46 participants took part in six focus groups divided into four groups of driv...