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Topic:Veterinary Science

Veterinary science and horses encompass the study and application of medical, surgical, and therapeutic practices to maintain and improve the health and welfare of equines. This field addresses a wide range of topics, including disease prevention, diagnosis, and treatment, as well as nutrition, reproduction, and behavior. Research in veterinary science for horses often involves understanding the pathophysiology of equine-specific diseases, developing advanced diagnostic techniques, and improving treatment protocols. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary science related to horses, providing insights into the latest advancements and methodologies in equine healthcare.
Domestic horses (Equus caballus) prefer to approach humans displaying a submissive body posture rather than a dominant body posture.
Animal cognition    October 13, 2017   Volume 21, Issue 2 307-312 doi: 10.1007/s10071-017-1140-4
Smith AV, Wilson C, McComb K, Proops L.Signals of dominance and submissiveness are central to conspecific communication in many species. For domestic animals, sensitivities to these signals in humans may also be beneficial. We presented domestic horses with a free choice between two unfamiliar humans, one adopting a submissive and the other a dominant body posture, with vocal and facial cues absent. Horses had previously been given food rewards by both human demonstrators, adopting neutral postures, to encourage approach behaviour. Across four counterbalanced test trials, horses showed a significant preference for approaching the s...
Influences of different dietary contents of macrominerals on the availability of trace elements in horses.
Journal of animal physiology and animal nutrition    October 13, 2017   Volume 102, Issue 2 e633-e640 doi: 10.1111/jpn.12805
Neustädter LT, Kamphues J, Ratert C.In this study, influences of a reduced macromineral intake on the trace element metabolism in horses at maintenance were investigated. Background of this study is the revised recommendation on the macromineral supply for horses (GfE ). Balance studies on three adult pony geldings with body weights of 405 / 348 / 384 kg were performed to obtain data on apparent digestibility (aD), retention and serum concentrations of different trace elements (Cu, Zn, Se) at different dietary macromineral levels. A mineral supplement or a complementary feed-with a reduced macromineral content-was added to a ha...
Prevalence of antimicrobial resistance from bacterial culture and susceptibility records from horse samples in South Africa.
Preventive veterinary medicine    October 12, 2017   Volume 148 37-43 doi: 10.1016/j.prevetmed.2017.10.004
Chipangura JK, Chetty T, Kgoete M, Naidoo V.The continuous increase in prevalence of antimicrobial resistant bacteria presents a significant public health problem and is an indicator that antimicrobial prudent usage guidelines are not being followed, especially in developing countries. Despite trends being available from numerous countries, there is little published for South Africa. This study was aimed at estimating the prevalence and trends of antimicrobial resistance from bacterial isolates from equine clinical samples submitted for culture and susceptibility testing to the veterinary bacteriology laboratory of the University of Pre...
To pace or not to pace: a pilot study of four- and five-gaited Icelandic horses homozygous for the DMRT3 ‘Gait Keeper’ mutation.
Animal genetics    October 11, 2017   Volume 48, Issue 6 694-697 doi: 10.1111/age.12610
Jäderkvist Fegraeus K, Hirschberg I, Árnason T, Andersson L, Velie BD, Andersson LS, Lindgren G.The Icelandic horse is a breed known mainly for its ability to perform the ambling four-beat gait 'tölt' and the lateral two-beat gait pace. The natural ability of the breed to perform these alternative gaits is highly desired by breeders. Therefore, the discovery that a nonsense mutation (C>A) in the DMRT3 gene was the main genetic factor for horses' ability to perform gaits in addition to walk, trot and canter was of great interest. Although several studies have demonstrated that homozygosity for the DMRT3 mutation is important for the ability to pace, only about 70% of the homozygous mutan...
Straight from the Horse’s “Mouth”: Genomic Epidemiology of an Icelandic Equine Epidemic.
mBio    October 10, 2017   Volume 8, Issue 5 doi: 10.1128/mBio.01613-17
Davies MR.Despite tight biosecurity measures, an outbreak of respiratory disease rapidly spread across the Icelandic equine population in 2010. Horse transportation was brought to a halt in order to contain the spread of the infectious agent. In a recent article, Björnsdóttir and colleagues (S. Björnsdóttir et al., mBio 8:e00826-17, 2017, https://doi.org/10.1128/mBio.00826-17) employ the power and resolution of "genomic epidemiology," the combination of whole genomic sequencing and epidemiological approaches, to examine the source and spread of the outbreak. Intriguingly, the outbreak was not viral ...
National equine survey uncovers common conditions.
The Veterinary record    October 8, 2017   Volume 181, Issue 14 359 doi: 10.1136/vr.j4586
No abstract available
Worms at the Royal Welsh Show.
The Veterinary record    October 8, 2017   Volume 181, Issue 14 376-377 doi: 10.1136/vr.j4548
Tyson F, Brophy PM, Morphew RM, Allen T, Pennington C, Thomas E.No abstract available
Morphological integration in the appendicular skeleton of two domestic taxa: the horse and donkey.
Proceedings. Biological sciences    October 6, 2017   Volume 284, Issue 1864 20171241 doi: 10.1098/rspb.2017.1241
Hanot P, Herrel A, Guintard C, Cornette R.Organisms are organized into suites of anatomical structures that typically covary when developmentally or functionally related, and this morphological integration plays a determinant role in evolutionary processes. Artificial selection on domestic species causes strong morphological changes over short time spans, frequently resulting in a wide and exaggerated phenotypic diversity. This raises the question of whether integration constrains the morphological diversification of domestic species and how natural and artificial selection may impact integration patterns. Here, we study the morpholog...
Equine chlamydiosis-An emerging infectious disease requiring a one health surveillance approach.
Zoonoses and public health    October 5, 2017   Volume 65, Issue 1 218-221 doi: 10.1111/zph.12391
Taylor KA, Durrheim D, Heller J, O'Rourke B, Hope K, Merritt T, Freeman P, Chicken C, Carrick J, Branley J, Massey P.Psittacosis is a rare but potentially fatal zoonosis caused by Chlamydia psittaci, an organism that is typically associated with bird contact. However C. psittaci is capable of infecting other non-avian hosts, such as horses, sheep, cattle and goats. Stud staff and veterinarians have significant exposure to parturient animals and reproductive materials in their routine work. To investigate the zoonotic potential associated with the emergence of C. psittaci as an abortifacient agent in horses, we established a programme of joint human and animal surveillance in a sentinel horse-breeding regio...
Longitudinal analysis of allergen-specific IgE and IgG subclasses as potential predictors of insect bite hypersensitivity following first exposure to Culicoides in Icelandic horses.
Veterinary dermatology    October 5, 2017   Volume 29, Issue 1 51-e22 doi: 10.1111/vde.12493
Ziegler A, Hamza E, Jonsdottir S, Rhyner C, Wagner B, Schüpbach G, Svansson V, Torsteinsdottir S, Marti E.Insect bite hypersensitivity (IBH) is an allergic dermatitis of horses caused by bites of Culicoides spp. IBH does not occur in Iceland because of the absence of Culicoides, but the prevalence is high in horses imported from Iceland to environments where Culicoides are present. Objective: Test, in a longitudinal study before and after Culicoides exposure, whether a primary sensitizing Culicoides allergen can be identified and if an increase of allergen-specific immunoglobulin (Ig)E or IgG subclasses precedes clinical signs of IBH. Methods: Thirty two horses imported from Iceland to Europe; 16 ...
Genetic diversity of piroplasmids species in equids from island of São Luís, northeastern Brazil. Braga MDSCO, Costa FN, Gomes DRM, Xavier DR, André MR, Gonçalves LR, Freschi CR, Machado RZ.Equine piroplasmosisis, a tick-borne disease caused by the intra-erythrocytic protozoans Babesia caballi and Theileria equi, has economic importance due to the international trade and the increased movement of horses all over the world. The goal of this study was to evaluate the occurrence of phylogenetic diversity of T. equi and B. caballi genotypes among infected equids from São Luís Island, state of Maranhão, northeastern Brazil. Between December of 2011 and June of 2012, EDTA-blood and serum samples were collected from 139 equids (90 donkeys, 39 horses and 10 mules). From 139 serum samp...
Stallion spermatozoa surviving freezing and thawing experience membrane depolarization and increased intracellular Na.
Andrology    October 3, 2017   Volume 5, Issue 6 1174-1182 doi: 10.1111/andr.12419
Ortega Ferrusola C, Anel-López L, Ortiz-Rodriguez JM, Martin Muñoz P, Alvarez M, de Paz P, Masot J, Redondo E, Balao da Silva C, Morrell JM....In order to gain insight of the modifications that freezing and thawing cause to the surviving population of spermatozoa, changes in the potential of the plasma membrane (Em) and intracellular Na content of stallion spermatozoa were investigated using flow cytometry. Moreover, caspase 3 activity was also investigated and the functionality of the Na -K ATPase pump was investigated before and after freezing and thawing. Cryopreservation caused a significant (p < 0.001) increase in the subpopulation of spermatozoa with depolarized sperm membranes, concomitantly with an increase (p < 0.0...
Validation of an indirect ELISA employing a chimeric recombinant gag and env peptide for the serological diagnosis of equine infectious anemia.
Journal of virological methods    October 3, 2017   Volume 251 111-117 doi: 10.1016/j.jviromet.2017.10.002
The National Reference Center for equine infectious anemia (EIA) validated a commercial ELISA (Eradikit EIAV Indirect ELISA, In3diagnostic, Turin, Italy) employing a chimeric recombinant gag and env peptide for the detection of EIA virus antibodies, following the guidelines of the World Organization for Animal Health. The validation parameters evaluated were: analytical sensitivity (Se) and specificity (Sp); diagnostic Se and Sp; precision, based on repeatability and reproducibility through the estimation of the standard deviation (SD) and the coefficient of variation (CV); accuracy, estimated...
A systematic literature search to identify performance measure outcomes used in clinical studies of racehorses.
Equine veterinary journal    October 2, 2017   Volume 50, Issue 3 304-311 doi: 10.1111/evj.12757
Wylie CE, Newton JR.Racing performance is often used as a measurable outcome variable in research studies investigating clinical diagnoses or interventions. However, the use of many different performance measures largely precludes conduct of meaningful comparative studies and, to date, those being used have not been collated. Objective: To systematically review the veterinary scientific literature for the use of racing performance as a measurable outcome variable in clinical studies of racehorses, collate and identify those most popular, and identify their advantages and disadvantages. Methods: Systematic literat...
An exploration of strategies used by dressage horses to control moments around the center of mass when performing passage.
PeerJ    September 28, 2017   Volume 5 e3866 doi: 10.7717/peerj.3866
Clayton HM, Hobbs SJ.Locomotion results from the generation of ground reaction forces (GRF) that cause translations of the center of mass (COM) and generate moments that rotate the body around the COM. The trot is a diagonally-synchronized gait performed by horses at intermediate locomotor speeds. Passage is a variant of the trot performed by highly-trained dressage horses. It is distinguished from trot by having a slow speed of progression combined with great animation of the limbs in the swing phase. The slow speed of passage challenges the horse's ability to control the sagittal-plane moments around the COM. Fo...
Emerging arboviruses in Quebec, Canada: assessing public health risk by serology in humans, horses and pet dogs.
Epidemiology and infection    September 28, 2017   Volume 145, Issue 14 2940-2948 doi: 10.1017/S0950268817002205
Rocheleau JP, Michel P, Lindsay LR, Drebot M, Dibernardo A, Ogden NH, Fortin A, Arsenault J.Periodic outbreaks of West Nile virus (WNV), Eastern equine encephalitis virus (EEEV) and to a lesser extent, California serogroup viruses (CSGV), have been reported in parts of Canada in the last decade. This study was designed to provide a broad assessment of arboviral activity in Quebec, Canada, by conducting serological surveys for these arboviruses in 196 horses, 1442 dogs and 485 humans. Sera were screened by a competitive enzyme linked immunosorbent assay and positive samples confirmed by plaque reduction neutralisation tests. The percentage of seropositive samples was 83·7%, 16·5%, 7...
Australian horse owners and their biosecurity practices in the context of Hendra virus.
Preventive veterinary medicine    September 28, 2017   Volume 148 28-36 doi: 10.1016/j.prevetmed.2017.09.013
Wiethoelter AK, Schembri N, Dhand NK, Sawford K, Taylor MR, Moloney B, Wright T, Kung N, Field HE, Toribio JLML.In recent years, outbreaks of exotic as well as newly emerging infectious diseases have highlighted the importance of biosecurity for the Australian horse industry. As the first potentially fatal zoonosis transmissible from horses to humans in Australia, Hendra virus has emphasised the need to incorporate sound hygiene and general biosecurity practices into day-to-day horse management. Recommended measures are widely publicised, but implementation is at the discretion of the individual owner. This cross-sectional study aimed to determine current levels of biosecurity of horse owners and to ide...
Equine analgesia guidelines to be developed for first-opinion practices.
The Veterinary record    September 25, 2017   Volume 181, Issue 12 305 doi: 10.1136/vr.j4352
No abstract available
Emergence of Nasal Carriage of ST80 and ST152 PVL+ Staphylococcus aureus Isolates from Livestock in Algeria.
Toxins    September 25, 2017   Volume 9, Issue 10 doi: 10.3390/toxins9100303
Agabou A, Ouchenane Z, Ngba Essebe C, Khemissi S, Chehboub MTE, Chehboub IB, Sotto A, Dunyach-Remy C, Lavigne JP.The spread of toxinogenic Staphylococcus aureus is a public health problem in Africa. The objectives of the study were to investigate the rate of S. aureus nasal carriage and molecular characteristics of these strains in livestock and humans in three Algerian provinces. Nasal samples were collected from camels, horses, cattle, sheep and monkeys, as well as humans in contact with them. S. aureus isolates were genotyped using DNA microarray. The rate of S. aureus nasal carriage varied between species: camels (53%), humans and monkeys (50%), sheep (44.2%), horses (15.2%) and cattle (15%). Nine me...
Quadruplex PCR assay for identification of Corynebacterium pseudotuberculosis differentiating biovar Ovis and Equi.
BMC veterinary research    September 25, 2017   Volume 13, Issue 1 290 doi: 10.1186/s12917-017-1210-5
Almeida S, Dorneles EMS, Diniz C, Abreu V, Sousa C, Alves J, Carneiro A, Bagano P, Spier S, Barh D, Lage AP, Figueiredo H, Azevedo V.Corynebacterium pseudotuberculosis is classified into two biovars, nitrate-negative biovar Ovis which is the etiologic agent of caseous lymphadenitis in small ruminants and nitrate-positive biovar Equi, which causes abscesses and ulcerative lymphangitis in equines. The aim of this study was to develop a quadruplex PCR assay that would allow simultaneous detection and biovar-typing of C. pseudotuberculosis. Methods: In the present study, genomes of C. pseudotuberculosis strains were used to identify the genes involved in the nitrate reduction pathway to improve a species identification three-pr...
Lipidomics of equine amniotic fluid: Identification of amphiphilic (O-acyl)-ω-hydroxy-fatty acids.
Theriogenology    September 20, 2017   Volume 105 120-125 doi: 10.1016/j.theriogenology.2017.09.012
Wood PL, Ball BA, Scoggin K, Troedsson MH, Squires EL.Amniotic fluid is essential for the growth and maturation of the fetus prior to parturition. While our knowledge of human amniotic fluid is extensive, current data for equine amniotic fluid is limited. We therefore undertook a detailed lipidomics analysis of equine amniotic fluid. Using a non-targeted high-resolution mass spectrometric lipidomics analysis of equine amniotic fluid, we were able to characterize a diverse array of individual lipids. This non-biased analytical approach detected, for the first time, the presence of (O-acyl)-ω-hydroxy-fatty acids (OAHFA) with up to 52 carbon chain ...
H2S Activated Drug Release from Protein Cages.
ACS applied materials & interfaces    September 19, 2017   Volume 9, Issue 39 33571-33575 doi: 10.1021/acsami.7b12524
Chen W, Zhang Y, Li X, Chen H, Sun J, Feng F.We took advantage of gasotransmitter HS as a chemical reaction-based trigger for controlled release of doxorubicin which is precoordinated by copper ions and enclosed in horse spleen apoferritin. The nanocomposite is stable at physiological pH and temperature before HS activation. The drug release process avoids disassembly of protein shells and is controllable by the strong affinity of sulfide with copper ions. The in vitro cytotoxicity assay indicates the antitumor effect of doxorubicin toward tumor cells could be achievable by HS activation.
Hoof Quality of Anglo-Arabian and Haflinger Horses.
Journal of veterinary research    September 19, 2017   Volume 61, Issue 3 367-373 doi: 10.1515/jvetres-2017-0049
Tocci R, Sargentini C, Martini A, Andrenelli L, Pezzati A, Benvenuti D, Giorgetti A.Foot quality is essential to the horse's movement. The barefoot approach favours the animal's welfare. Environment and selection determine hoof characteristics. Methods: Hoof characteristics of eight Anglo-Arabian (AA) and nine Haflinger (HA) horses were studied. After a preliminary visual analysis of feet, nail samples were collected after trimming for physico-chemical analysis. The parameters were submitted to analysis of variance. A principal component analysis and a Pearson correlation were used to compare mineral contents. Results: The hooves of both breeds were healthy and solid. The hoo...
Zinc silicate mineral-coated scaffold improved in vitro osteogenic differentiation of equine adipose-derived mesenchymal stem cells.
Research in veterinary science    September 18, 2017   Volume 124 444-451 doi: 10.1016/j.rvsc.2017.09.015
Bageshlooyafshar B, Vakilian S, Kehtari M, Eslami-Arshaghi T, Rafeie F, Ramezanifard R, Rahchamani R, Mohammadi-Sangcheshmeh A, Mostafaloo Y....In current study we aimed to coat the PLLA scaffold with zinc (Zn) silicate mineral nanoparticles. Then, using equine adipose-derived stem cells (ASCs) we intended to compare the osteogenic induction potency of Zn silicate mineral-coated PLLA scaffold with uncoated PLLA scaffold and tissue culture plastic (TCPS). Adipose tissues were collected from 3 horses, and isolation of ASCs was achieved by enzymatic digestion. PLLA scaffold was successfully prepared using a phase separation method and coated with Zn silicate mineral nanoparticles. The coating efficiency was then characterized by scanning...
Improved reliability of serological tools for the diagnosis of West Nile fever in horses within Europe.
PLoS neglected tropical diseases    September 15, 2017   Volume 11, Issue 9 e0005936 doi: 10.1371/journal.pntd.0005936
Beck C, Lowenski S, Durand B, Bahuon C, Zientara S, Lecollinet S.West Nile Fever is a zoonotic disease caused by a mosquito-borne flavivirus, WNV. By its clinical sensitivity to the disease, the horse is a useful sentinel of infection. Because of the virus' low-level, short-term viraemia in horses, the primary tools used to diagnose WNV are serological tests. Inter-laboratory proficiency tests (ILPTs) were held in 2010 and 2013 to evaluate WNV serological diagnostic tools suited for the European network of National Reference Laboratories (NRLs) for equine diseases. These ILPTs were designed to evaluate the laboratories' and methods' performances in detectin...
Surface glycan pattern of canine, equine, and ovine bone marrow-derived mesenchymal stem cells.
Cytometry. Part A : the journal of the International Society for Analytical Cytology    September 14, 2017   Volume 93, Issue 1 73-81 doi: 10.1002/cyto.a.23241
Desantis S, Accogli G, Crovace A, Francioso EG, Crovace AM.The use of bone marrow-derived mesenchymal stem cells (MSCs) for clinical and experimental studies is increasing, but full characterization of MSCs in veterinary species is hindered by the variability in species-specific cell surface marker expression and antibody cross reactivity. Recent studies demonstrated that the glycans in the glycocalyx of MSCs are promising candidates as cell biomarkers. In the present study, we analyzed the glycocalyx of canine MSCs (cMSCs), ovine MSCs (oMSCs), and equine MSCs (eMSCs) using a cell microarray procedure in which MSCs were spotted on microarray slides an...
Perceptions of Equid Well Being Well-Being in South Dakota.
Journal of applied animal welfare science : JAAWS    September 14, 2017   Volume 21, Issue 1 40-68 doi: 10.1080/10888705.2017.1372199
McNeill LR, Bott RC, Mastellar SL, Djira G, Carroll HK.In South Dakota, the status of equid well being is relatively unknown. This study sought to (a) gain understanding about the current perceptions of nonhuman animal well being in South Dakota, with an emphasis on horses and other equids; (b) determine the level of care equids are reportedly receiving and the perceived challenges to equine well being in South Dakota, and (c) determine if people from diverse geographical locations (east or west of the Missouri River) have similar views on the well being of equids in South Dakota. Respondents indicated the current level of equid well being in Sout...
Single nucleotide polymorphisms for DNA typing in the domestic horse.
Animal genetics    September 13, 2017   Volume 48, Issue 6 669-676 doi: 10.1111/age.12608
Holl HM, Vanhnasy J, Everts RE, Hoefs-Martin K, Cook D, Brooks SA, Carpenter ML, Bustamante CD, Lafayette C.Genetic markers are important resources for individual identification and parentage assessment. Although short tandem repeats (STRs) have been the traditional DNA marker, technological advances have led to single nucleotide polymorphisms (SNPs) becoming an attractive alternative. SNPs can be highly multiplexed and automatically scored, which allows for easier standardization and sharing among laboratories. Equine parentage is currently assessed using STRs. We obtained a publicly available SNP dataset of 729 horses representing 32 diverse breeds. A proposed set of 101 SNPs was analyzed for DNA ...
Interobserver Variation in the Diagnosis of Neurologic Abnormalities in the Horse.
Journal of veterinary internal medicine    September 9, 2017   Volume 31, Issue 6 1871-1876 doi: 10.1111/jvim.14822
Saville WJA, Reed SM, Dubey JP, Granstrom DE, Morley PS, Hinchcliff KW, Kohn CW, Wittum TE, Workman JD.The diagnosis of equine protozoal myeloencephalitis (EPM) relies heavily on the clinical examination. The accurate identification of neurologic signs during a clinical examination is critical to the interpretation of laboratory results. Objective: To investigate the level of agreement between board-certified veterinary internists when performing neurologic examinations in horses. Methods: Ninety-seven horses admitted to the Veterinary Teaching Hospital at The Ohio State University from December 1997 to June 1998. Methods: A prospective epidemiologic research design was used. Horses enrolled in...
Equine Assisted Interventions (EAIs): Methodological Considerations for Stress Assessment in Horses.
Veterinary sciences    September 8, 2017   Volume 4, Issue 3 44 doi: 10.3390/vetsci4030044
De Santis M, Contalbrigo L, Borgi M, Cirulli F, Luzi F, Redaelli V, Stefani A, Toson M, Odore R, Vercelli C, Valle E, Farina L.Equine assisted interventions (EAIs) are recently facing an increasing popularity, and are characterized by a wide diversity of practices. However, information on the welfare of animals involved in this kind of activity is often lacking. Horses are highly susceptible to work stressors related to physical constraints and/or to the need to control emotions while interacting with humans. Considerations of the emotional state of horses involved in EAIs have multiple valences: for the safety of humans and animals involved, for the quality and efficacy of interventions, as well as for ethical reason...
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