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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Transcutaneous direct current cardioversion in a foal with lone atrial fibrillation.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    November 1, 2016   Volume 19, Issue 1 99-105 doi: 10.1016/j.jvc.2016.09.002
Potter BM, Scansen BA, Dunbar LK, Reed SM, Toribio RE.There are rare published reports of atrial fibrillation (AF) in foals, all of which are associated with structural heart disease or within the adaptive period of newborns. This report describes a 3-month-old Thoroughbred filly with AF and a structurally normal heart on echocardiography. Medical cardioversion of the foal's AF was attempted with three 20mg/kg doses of quinidine sulfate therapy without success. Timed, transcutaneous, direct current cardioversion was successfully performed using adhesive patches on the midthorax in conjunction with intravenous procainamide at a total dose of 20mg/...
Mitochondrial ATP is required for the maintenance of membrane integrity in stallion spermatozoa, whereas motility requires both glycolysis and oxidative phosphorylation.
Reproduction (Cambridge, England)    November 1, 2016   Volume 152, Issue 6 683-694 doi: 10.1530/REP-16-0409
Davila MP, Muñoz PM, Bolaños JM, Stout TA, Gadella BM, Tapia JA, da Silva CB, Ferrusola CO, Peña FJ.To investigate the hypothesis that oxidative phosphorylation is a major source of ATP to fuel stallion sperm motility, oxidative phosphorylation was suppressed using the mitochondrial uncouplers CCCP and 2,4,-dinitrophenol (DNP) and by inhibiting mitochondrial respiration at complex IV using sodium cyanide or at the level of ATP synthase using oligomycin-A. As mitochondrial dysfunction may also lead to oxidative stress, production of reactive oxygen species was monitored simultaneously. All inhibitors reduced ATP content, but oligomycin-A did so most profoundly. Oligomycin-A and CCCP also sign...
The Lin28 Expression in Stallion Testes.
PloS one    October 31, 2016   Volume 11, Issue 10 e0165011 doi: 10.1371/journal.pone.0165011
Lee G, Jung H, Yoon M.The molecular markers for specific germ cell stages can be utilized for identifying, monitoring, and separating a particular stage of germ cells. The RNA-binding protein Lin28 is expressed in gonocytes of human fetal testes. The Lin28 expression is restricted to a very small population of spermatogonial cells in human, mice, and monkey. The main objective of this study was to investigate the expression pattern of Lin28 in stallion testes at different reproductive stages. Based on the presence or absence of full spermatogenesis and lumina in seminiferous tubules, the testicular samples were cat...
Equine disease surveillance: quarterly summary.
The Veterinary record    October 30, 2016   Volume 179, Issue 17 428-431 doi: 10.1136/vr.i5679
of surveillance testing, April to June 2016Continuing reports of abortion due to equine herpesvirus type 1 infectionInternational disease occurrence in the second quarter of 2016These are among matters discussed in the most recent quarterly equine disease surveillance report, prepared by Defra, the Animal Health Trust and the British Equine Veterinary Association.
Development and application of a UHPLC-MS/MS method for the simultaneous determination of 17 steroidal hormones in equine serum.
Journal of mass spectrometry : JMS    October 30, 2016   Volume 52, Issue 1 22-29 doi: 10.1002/jms.3896
Genangeli M, Caprioli G, Cortese M, Laus F, Matteucci M, Petrelli R, Ricciutelli M, Sagratini G, Sartori S, Vittori S.A new, fast and simple analytical method that is able to identify and quantify simultaneously 17 steroid hormones and metabolites (pregnenolone, 17-OH-pregnenolone, progesterone, 17-OH-progesterone, androsterone, androstenedione, dehydroepiandrosterone, dehydroepiandrosterone sulfate, testosterone, cortisol, corticosterone, aldosterone, 11-deoxycortisol, 11-deoxycorticosterone, dihydrotestosterone, estrone and estradiol) has been developed in equine serum using the ultra-high-performance liquid chromatography-tandem mass spectrometry technique. A total of 400 µl of sample was deproteinized ...
Autologous Conditioned Serum.
Physical medicine and rehabilitation clinics of North America    October 30, 2016   Volume 27, Issue 4 893-908 doi: 10.1016/j.pmr.2016.06.003
Evans CH, Chevalier X, Wehling P.Autologous conditioned serum was developed in the mid 1990s as an expeditious, practical, and relatively inexpensive means of generating the interleukin-1 receptor antagonist, a naturally occurring inhibitor of the cytokine interleukin-1. The latter is thought to be an important mediator of inflammation, pain, and tissue destruction in musculoskeletal conditions. ACS has been widely and successfully used in the local treatment of human and equine osteoarthritis and radicular compression; it has also shown promise in treating tendinopathies, muscle injuries, and tunnel widening after reconstruc...
Glucocorticoid metabolism in equine follicles and oocytes.
Domestic animal endocrinology    October 29, 2016   Volume 59 11-22 doi: 10.1016/j.domaniend.2016.10.004
Scarlet D, Ille N, Ertl R, Alves BG, Gastal GDA, Paiva SO, Gastal MO, Gastal EL, Aurich C.The objective of this study was to determine whether (1) systemic and intrafollicular cortisol concentrations in horses are directly related and (2) supraphysiological levels of glucocorticoids affect in vitro maturation (IVM) rates of oocytes. Specifically, we studied the (1) changes in the intrafollicular cortisol and progesterone in context with granulosa cell gene expression during maturation of equine follicles (from 5-9 mm, 10-14 mm, 15-19 mm, 20-24 mm, and ≥25 mm in diameter) and (2) effects of cortisol supplementation on IVM rates and gene expression of equine cumulus-oocyte comple...
Genetic characterization of the Miyako horse based on polymorphisms of microsatellites and mitochondrial DNA.
The Journal of veterinary medical science    October 28, 2016   Volume 79, Issue 1 218-223 doi: 10.1292/jvms.16-0111
Senju N, Tozaki T, Kakoi H, Almunia J, Maeda M, Matsuyama R, Takasu M.To help plan conservation of the endangered Miyako horse, a biological resource of the Miyako Islands in Japan, we characterized the genetics of the breed by genotyping 32 microsatellites and identifying mitochondrial DNA haplotypes. We also calculated genetic distances between individuals based on the proportion of shared alleles and visualized the genetic relationships with a phylogenetic tree. Two important results were obtained. One is that accurate pedigree registration of the horse by using microsatellites is possible, as the exclusion power of parentage testing is 0.999998. Another is t...
Prevalence of obesity and owners’ perceptions of body condition in pleasure horses and ponies in south-eastern Australia.
Australian veterinary journal    October 28, 2016   Volume 94, Issue 11 427-432 doi: 10.1111/avj.12506
Potter SJ, Bamford NJ, Harris PA, Bailey SR.To determine the prevalence of obesity within a population of pleasure horses and ponies in Victoria, Australia, and to compare owners' perceptions of their animals' body condition with researchers' assessments. Methods: An observational study plus owner questionnaire. Methods: Ten Pony Club rallies in different regions of Victoria were attended. Information regarding 229 horses and ponies were obtained from owner questionnaires, and owners' perceptions of the current body condition of their animals were assessed using a visual analogue scale. Body condition score (BCS) was assessed by the res...
Dwarfism with joint laxity in Friesian horses is associated with a splice site mutation in B4GALT7.
BMC genomics    October 28, 2016   Volume 17, Issue 1 839 doi: 10.1186/s12864-016-3186-0
Leegwater PA, Vos-Loohuis M, Ducro BJ, Boegheim IJ, van Steenbeek FG, Nijman IJ, Monroe GR, Bastiaansen JW, Dibbits BW, van de Goor LH, Hellinga I....Inbreeding and population bottlenecks in the ancestry of Friesian horses has led to health issues such as dwarfism. The limbs of dwarfs are short and the ribs are protruding inwards at the costochondral junction, while the head and back appear normal. A striking feature of the condition is the flexor tendon laxity that leads to hyperextension of the fetlock joints. The growth plates of dwarfs display disorganized and thickened chondrocyte columns. The aim of this study was to identify the gene defect that causes the recessively inherited trait in Friesian horses to understand the disease proce...
Molecular Detection and Genotyping of Coxiella-Like Endosymbionts in Ticks that Infest Horses in South Korea.
PloS one    October 28, 2016   Volume 11, Issue 10 e0165784 doi: 10.1371/journal.pone.0165784
Seo MG, Lee SH, Ouh IO, Lee GH, Goo YK, Kim S, Kwon OD, Kwak D.Members of the genus Coxiella can be transmitted from ticks to humans during contact with animals; Coxiella may thus spread from the infected horses or ticks to humans. In this study, the presence of Coxiella burnetii and Coxiella-like endosymbionts (CLE) in ticks found on infested horses was determined using PCR and genotyping. A total of 213 ticks were randomly collected from 51 horses (4-5 ticks per horse) raised on Jeju Island, Korea, between 2009 and 2013. All ticks were morphologically identified as adult Haemaphysalis longicornis, a predominant tick species widespread in Korea. Based on...
Effect of topical ophthalmic latanoprost 0.005% solution alone and in combination with diclofenac 0.1% solution in healthy horses: a pilot study.
Veterinary ophthalmology    October 28, 2016   Volume 20, Issue 5 398-404 doi: 10.1111/vop.12439
Tofflemire K, Whitley EM, Allbaugh R, Ben-Shlomo G, Griggs A, Strong T, Whitley RD.To evaluate the effect of topical ophthalmic 0.005% latanoprost alone and in combination with 0.1% diclofenac on healthy horses. Methods: Twelve healthy adult horses. Methods: A randomized, masked crossover design was used with horses divided into three groups for once daily treatment in one randomly selected eye. For arm 1 of the study, Group D (n = 3) received 0.1% diclofenac, Group L (n = 3) received 0.005% latanoprost, and Group DL (n = 6) received 0.005% latanoprost and 0.2 ml of 0.1% diclofenac. For arm 2 of the study, horses from Group D and L were placed into Group DL and horses from G...
Novel equine tissue miRNAs and breed-related miRNA expressed in serum.
BMC genomics    October 26, 2016   Volume 17, Issue 1 831 doi: 10.1186/s12864-016-3168-2
Pacholewska A, Mach N, Mata X, Vaiman A, Schibler L, Barrey E, Gerber V.MiRNAs regulate multiple genes at the post-transcriptional level and therefore play an important role in many biological processes. It has been suggested that miRNA exported outside the cells contribute to inter-cellular communication. Consequently, circulating miRNAs are of particular interest and are promising biomarkers for many diseases. The number of miRNAs annotated in the horse genome is much lower compared to model organisms like human and mouse. We therefore aimed to identify novel equine miRNAs for tissue types and breed in serum. We analysed 71 small RNA-seq libraries derived from n...
The presence of seminal plasma, especially derived from stallion semen, helps preserve chilled Asian elephant (Elephas maximus) sperm motility.
Andrologia    October 26, 2016   Volume 49, Issue 6 doi: 10.1111/and.12690
Pinyopummin A, Mahasawangkul S, Kornkaewrat K, Rattanapirom S, Leartsang W, Kitkha S.The effects of seminal plasma (SP), derived from autologous, homologous and heterologous species (stallion, boar and dog) on chilled Asian elephant sperm quality, were determined. Semen was collected from eight males and samples with ≥30% motile spermatozoa were used in the study. Semen was diluted with Tris-glucose-egg yolk extender, supplemented with different SP types and preserved at 4°C for 48 hr. Experiment 1 (n = 31), showed that the presence of SP (autologous) helped to preserve sperm quality in terms of sperm motility and acrosome integrity (p < .05). Homologous SP did not ...
The stability and microbial contamination of bupivacaine, lidocaine and mepivacaine used for lameness diagnostics in horses.
Veterinary journal (London, England : 1997)    October 25, 2016   Volume 218 7-12 doi: 10.1016/j.tvjl.2016.10.008
Adler DM, Cornett C, Damborg P, Verwilghen DR.Local anaesthetics (LAs) are frequently used for diagnostic procedures in equine veterinary practice. The objective of this study was to investigate the physico-chemical stability and bacterial contamination of bupivacaine, lidocaine and mepivacaine used for lameness examinations in horses. The LAs were stored in 12 different groups at different temperatures (-18 °C to 70 °C), light intensities and in common veterinary field conditions for up to 16 months. The pH, presence of bacterial contamination and concentrations of LAs and methylparaben (a preservative present in lidocaine) were de...
Transcriptome analysis of equine sarcoids.
Veterinary and comparative oncology    October 25, 2016   Volume 15, Issue 4 1370-1381 doi: 10.1111/vco.12279
Semik E, Gurgul A, Ząbek T, Ropka-Molik K, Koch C, Mählmann K, Bugno-Poniewierska M.Equine sarcoids are the most commonly detected skin tumours in Equidae. In the present research, a comparative transcriptomic analysis was performed which aimed at looking inside a tumour biology and identification of the expression profile as a potential source of cancer specific genes useful as biomarkers. We have used Horse Gene Expression Microarray data from matched equine sarcoids and tumour-distant skin samples. In total, 901 significantly differentially expressed genes (DEGs) between lesional and healthy skin samples have been identified (fold change ≥ 2; P < 0.05). The la...
Horse Injury during Non-Commercial Transport: Findings from Researcher-Assisted Intercept Surveys at Southeastern Australian Equestrian Events.
Animals : an open access journal from MDPI    October 25, 2016   Volume 6, Issue 11 65 doi: 10.3390/ani6110065
Riley CB, Noble BR, Bridges J, Hazel SJ, Thompson K.Equine transportation research has largely focused on the commercial land movement of horses. Data on the incidence and factors associated with horse injuries during non-commercial transportation (privately owned horse trucks and trailers) is scant. This study surveyed 223 drivers transporting horses to 12 equestrian events in southeastern Australia. Data collected encompassed driver demographics, travel practice, vehicle characteristics, and incidents involving horse injury. Approximately 25% (55/223) of participants reported that their horses were injured during transportation. Of these 72% ...
Molecular characterization and multilocus genotypes of Enterocytozoon bieneusi among horses in southwestern China.
Parasites & vectors    October 25, 2016   Volume 9, Issue 1 561 doi: 10.1186/s13071-016-1844-3
Deng L, Li W, Zhong Z, Gong C, Liu X, Huang X, Xiao L, Zhao R, Wang W, Feng F, Zhang Y, Hu Y, Fu H, He M, Zhang Y, Wu K, Peng G.Enterocytozoon bieneusi is one of the most prevalent causative species of diarrhea and enteric diseases in various hosts. E. bieneusi has been identified in humans, mammals, birds, rodents and reptiles in China, but few studies have reported E. bieneusi in horses. Therefore, the present study was conducted to assess the prevalence, molecular characteristics and zoonotic potential of E. bieneusi among horses in southwestern China. Three hundred and thirty-three fecal specimens were collected from horses on five farms in the Sichuan and Yunnan provinces of southwestern China. The prevalence of E...
Pulmonary function among Latino thoroughbred horse farmworkers.
American journal of industrial medicine    October 24, 2016   Volume 60, Issue 1 35-44 doi: 10.1002/ajim.22667
Flunker JC, Clouser JM, Mannino D, Swanberg J.Latino thoroughbred workers may be at risk for developing abnormal pulmonary function related to occupational exposures. Methods: Eighty worker participants were recruited via community-based purposive sampling. Questionnaires and spirometry tests were administered by trained lay health promoters. Demographic and occupational factors were assessed for associations with respiratory outcomes via multivariable logistic regression. Results: Twenty-seven percent of participants exhibited abnormal pulmonary function (primarily restrictive), 79% reported any respiratory symptoms, and 94% infrequently...
Population genetic study over 32,000 equines from Uruguay using seventeen forensically informative STR loci.
Forensic science international. Genetics    October 24, 2016   Volume 26 e19-e22 doi: 10.1016/j.fsigen.2016.10.011
Gastaldo AZ, Rodenbusch R, Fossati R, Azambuja CJ, Alho CS.No abstract available
Periparturient characteristics of mares and their foals on a New Zealand Thoroughbred stud farm.
New Zealand veterinary journal    October 24, 2016   Volume 65, Issue 1 24-29 doi: 10.1080/00480169.2016.1244021
Rosales C, Krekeler N, Tennent-Brown B, Stevenson MA, Hanlon D.To describe selected periparturient variables in a sample of Thoroughbred mares and their foals on a commercial stud farm in New Zealand. Methods: Data were collected for 969 foaling records, from 592 mares, by foaling attendants from one Thoroughbred stud farm in the Waikato region of New Zealand for the breeding seasons 2008-2013, inclusive, and collated retrospectively. The associations between mare- and foal-level variables and gestation length, time of birth (expressed as the number of hours after midday), fetal membrane retention time, time for the foal to stand and suckle after birth, a...
Support for equine vets juggling practice and parenthood.
The Veterinary record    October 23, 2016   Volume 179, Issue 16 397-399 doi: 10.1136/vr.i5593
This year's BEVA congress saw the launch of MumsVet, an online support network for working parents. Set up by four working vet mums, including the new BEVA president, Vicki Nicholls, the network - for dads as well - aims to help vets balance work and parenthood. Gill Harris reports.
What is your diagnosis? Peritoneal effusion in a 10-year-old horse.
Veterinary clinical pathology    October 23, 2016   Volume 45, Issue 4 723-724 doi: 10.1111/vcp.12418
McLaren PJ, Jocelyn NA.No abstract available
Equine antibiotic recalled.
The Veterinary record    October 23, 2016   Volume 179, Issue 16 394 doi: 10.1136/vr.i5622
No abstract available
Comparison of Tube, Gel, and Immunochromatographic Strip Methods for Evaluation of Blood Transfusion Compatibility in Horses.
Journal of veterinary internal medicine    October 22, 2016   Volume 30, Issue 6 1864-1871 doi: 10.1111/jvim.14604
Luethy D, Owens SD, Stefanovski D, Nolen-Walston R, Giger U.Assessment of blood compatibility, typically by tube agglutination (TUBE) and hemolysis crossmatch or, less commonly, by blood typing and alloantibody screening, often is performed before blood transfusion in horses. In contrast, gel column (GEL) and immunochromatographic strip (STRIP) techniques are preferred for compatibility testing in dogs and cats. Objective: To determine the accuracy of novel and standard crossmatch and typing methods. Methods: Thirty-eight healthy horses, previously blood typed and alloantibody screened. Methods: TUBE and GEL crossmatches were performed on 146 different...
West Nile virus ‘circulation’ in Vojvodina, Serbia: Mosquito, bird, horse and human surveillance.
Molecular and cellular probes    October 21, 2016   Volume 31 28-36 doi: 10.1016/j.mcp.2016.10.011
Efforts to detect West Nile virus (WNV) in the Vojvodina province, northern Serbia, commenced with human and mosquito surveillance in 2005, followed by horse (2009) and wild bird (2012) surveillance. The knowledge obtained regarding WNV circulation, combined with the need for timely detection of virus activity and risk assessment resulted in the implementation of a national surveillance programme integrating mosquito, horse and bird surveillance in 2014. From 2013, the system showed highly satisfactory results in terms of area specificity (the capacity to indicate the spatial distribution of t...
Investigating interactions between UK horse owners and prescribers of anthelmintics.
Preventive veterinary medicine    October 21, 2016   Volume 135 17-27 doi: 10.1016/j.prevetmed.2016.10.017
Easton S, Pinchbeck GL, Tzelos T, Bartley DJ, Hotchkiss E, Hodgkinson JE, Matthews JB.Helminths are common pathogens of equids and anthelmintic resistance is a major issue in cyathostomin species and Parascaris equorum. At the heart of mitigating the impact of increasing anthelmintic resistance levels, is the responsible dissemination and use of these medicines following best practice principles. There is a paucity of information on interactions between horse owners and anthelmintic prescribers and how this shapes control. Here, a study was undertaken to determine opinions and experiences of horse owners as they relate to anthelmintics purchase and implementation of best practi...
Diet-Dependent Modular Dynamic Interactions of the Equine Cecal Microbiota.
Microbes and environments    October 21, 2016   Volume 31, Issue 4 378-386 doi: 10.1264/jsme2.ME16061
Kristoffersen C, Jensen RB, Avershina E, Austbø D, Tauson AH, Rudi K.Knowledge on dynamic interactions in microbiota is pivotal for understanding the role of bacteria in the gut. We herein present comprehensive dynamic models of the horse cecal microbiota, which include short-chained fatty acids, carbohydrate metabolic networks, and taxonomy. Dynamic models were derived from time-series data in a crossover experiment in which four cecum-cannulated horses were fed a starch-rich diet of hay supplemented with barley (starch intake 2 g kg body weight per day) and a fiber-rich diet of only hay. Cecal contents were sampled via the cannula each h for 24 h for both die...
Body condition score, morphometric measurements and estimation of body weight in mature Icelandic horses in Denmark.
Acta veterinaria Scandinavica    October 20, 2016   Volume 58, Issue Suppl 1 59 doi: 10.1186/s13028-016-0240-5
Jensen RB, Danielsen SH, Tauson AH.Obesity is related to the development of several diseases like insulin resistance and laminitis in horses. The prevalence of obesity among mature Icelandic horses in Denmark has not been investigated previously. This study aimed to find the prevalence of obesity, to compare body condition score (BCS) based on owner perception with that of an experienced person and to correlate the BCS to body weight (BW) and morphometric measures in a group of mature Icelandic horses in Denmark. A total of 254 Icelandic horses (≥4 years; 140 geldings, 105 mares, 9 stallions) from 46 different farms were inc...
Relationships between body condition score and ultrasound skin-associated subcutaneous fat depth in equids.
Acta veterinaria Scandinavica    October 20, 2016   Volume 58, Issue Suppl 1 62 doi: 10.1186/s13028-016-0243-2
Silva SR, Payan-Carreira R, Quaresma M, Guedes CM, Santos AS.In equids, health and welfare depend on body composition. A growing number of equids are now used as leisure and companion animals, and often found overfeed. The need for a close monitoring of body fatness led to the search for tools allowing a rapid and non-invasive estimation of fatness. This study intends to assess real-time ultrasonography (RTU) usefulness in establishing a relationship between ultrasound measures of subcutaneous fat-plus-skin thickness (SF-Skin) and body condition score (BCS) in horses and donkeys. Forty-three healthy animals (16 donkeys and 27 horses) were used in this s...