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Topic:Infection

Infections in horses encompass a range of diseases caused by various pathogens, including bacteria, viruses, fungi, and parasites. These infections can affect different systems within the horse, such as the respiratory, gastrointestinal, and integumentary systems, leading to a variety of clinical signs depending on the pathogen and the severity of the infection. Common infectious diseases in horses include equine influenza, strangles, and equine herpesvirus. Diagnosis often involves clinical examination, laboratory testing, and sometimes imaging, to identify the causative agent and assess the extent of the disease. Treatment strategies may include antimicrobial therapy, supportive care, and preventive measures such as vaccination and biosecurity practices. This page aggregates peer-reviewed research studies and scholarly articles that explore the pathogenesis, diagnosis, treatment, and prevention of infectious diseases in equine populations.
Computed Tomographic Lesion Descriptors in Foals With Hematogenous Osteomyelitis: Interobserver Agreement and Association With Outcome. Gustafsson K, Longo M, Vanderperren K, Haardt H, Haspeslagh M, Stas E, De Zani D, Buyck C, Robert M, Zani DD.Computed tomography (CT) is increasingly used to diagnose osteomyelitis in foals, but the prognostic value and interobserver reproducibility of specific CT lesion descriptors remain unclear. This multicenter retrospective study aimed to characterize CT features of hematogenous osteomyelitis in foals using a structured radiologic feature set, assess interobserver agreement, and evaluate associations between CT descriptors and survival to hospital discharge and long-term survival. We hypothesized that CT features considered aggressive, including a long transition zone, permeative or moth-eaten o...
No evidence of H5N1 avian influenza virus infection in Japanese horses in 2025.
Journal of equine veterinary science    August 26, 2026   Volume 167 106131 doi: 10.1016/j.jevs.2026.106131
Kawanishi N, Hiono T, Kambayashi Y, Bannai H, Tsujimura K, Yamanaka T, Isoda N, Sakoda Y, Nemoto M.The global spillover of clade 2.3.4.4b H5N1 highly pathogenic avian influenza virus into mammalian hosts has become a concern for public health as well as for the equine industry. However, previous reports on H5N1 natural infection and the presence of specific antibodies in horses remain limited. Therefore, we conducted a serosurveillance study to assess the prevalence of H5N1 antibodies in serum samples collected from 400 horses in Japan. Samples were screened using competitive ELISA (cELISA) and hemagglutination inhibition (HI) tests against H5-recombinant protein and H5N1 viral antigen, res...
Correction: Epidemiological study of strongyle infections in equines in Egypt: prevalence and risk factors.
Frontiers in veterinary science    August 26, 2026   Volume 13 1974891 doi: 10.3389/fvets.2026.1974891
[This corrects the article DOI: 10.3389/fvets.2026.1901312.].
Development and Evaluation of an Indirect ELISA for Strangles Based on an Untagged EQ8-SclF Fusion Protein.
Veterinary sciences    August 26, 2026   Volume 13, Issue 9 866 doi: 10.3390/vetsci13090866
Sun R, Zu H, Wang M, Guo W, Wang X, Yang Q.Strangles, caused by subsp. (), is a highly contagious respiratory disease that causes substantial economic losses to the horse industry worldwide. Serological diagnosis currently relies mainly on the imported IDvet dual-antigen sandwich ELISA kit, which shows good diagnostic performance but is expensive and lacks a domestic alternative in China, thereby limiting its routine use in primary veterinary settings. The aim of this study was to develop a domestic indirect ELISA based on novel antigen targets and an untagged antigen purification strategy. Using comparative bioinformatics analyses, ...
Evidence-based interpretation of uterine cultures in mares: Linking bacterial growth patterns to endometrial inflammation.
PloS one    August 25, 2026   Volume 21, Issue 8 e0356822 doi: 10.1371/journal.pone.0356822
Yáñez U, Krupa M, Gibbons J, Storme J, Lewis N, Pascottini OB.We evaluated uterine bacterial growth patterns and their association with endometrial inflammation (EI) in equine samples collected using uterine swabs (US) or low-volume uterine lavage (UL). A database including 1,545 US and 2,066 UL with cytological and bacteriological results was retrospectively analysed. Endometrial inflammation was defined as ≥2 polymorphonuclear cells per high-power field, and bacterial culture was considered positive when aerobic growth occurred within 48 h, with the number of bacterial isolates per sample recorded (0, 1, 2, or ≥3). Data were analysed using generali...
Surgical Management of Unilateral Maxillary Molar Teeth Impaction in a Horse.
Journal of veterinary dentistry    August 24, 2026   8987564261478738 doi: 10.1177/08987564261478738
Clarysse M, Korsos S, Cuypers C, Raes E, Vlaminck L.Impaction of equine permanent cheek teeth is most commonly reported in the mandible, whereas maxillary involvement is rare. This report describes an uncommon presentation of congenital impaction of 3 successive maxillary molar teeth in a 4-year-old mare. Computed tomography revealed complex spatial relationships between the impacted teeth, the sinus floor and adjacent structures, which were not fully appreciated on conventional radiography and were essential for surgical planning. Surgical extraction via a maxillary sinus bone flap permitted controlled sectioning and subsequent removal of all ...
Isolation of Moraxella spp. strains in horses.
Veterinaria italiana    August 24, 2026   Volume 62, Issue 3 doi: 10.12834/VetIt.4010.40914.2
Grassi L, De Zan G, Deotto S, Costa F, Lanzi P, Genero N, Clapiz L, Ustulin M, Cocchi M.Two species of Moraxella were isolated from swabs obtained from two symptomatic horses suffering from conjunctivitis and rhinitis. The isolates were identified via MALDI-TOF as Moraxella osloensis and Moraxella equi respectively, with a good genus identification and a probable species identification score. The first one was also confirmed by BLAST sequence analysis with a high homology (99%). Antimicrobial susceptibility testing obtained by minimum inhibitory concentration method showed that the two isolates were sensitive to all the tested molecules. The therapeutic protocols applied had an e...
Microbiological, Molecular Diagnosis and Antimicrobial Resistance of Bordetella bronchiseptica in the Equine Reproductive Tract in Brazil.
Veterinary medicine and science    August 21, 2026   Volume 12, Issue 5 e71146 doi: 10.1002/vms3.71146
Gallo SSM, Bernardino MLA, Júnior LASDM, Oliveira FCR, Barreto MAP, Folly MM.The genus Bordetella comprises 16 species of aerobic Gram-negative bacteria, with the most notable being B. pertussis, B. parapertussis and B. bronchiseptica. The latter stands out for its ability to infect various hosts, causing both respiratory and reproductive issues, such as endometritis and infertility in mares. These infections impair reproductive efficiency and facilitate the spread of the pathogen among susceptible animals. Objective: The present study aimed to report the isolation and molecular diagnosis of B. bronchiseptica associated with endometritis and infertility in mares in Bra...
[Puncture wounds of the equine hoof – a retrospective study of 96 cases – Part 2: Management and prognosis].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    August 20, 2026   Volume 54, Issue 4 244-252 doi: 10.1055/a-2794-3232
Herschel TL, Winter K, Scharner D.Puncture wounds are a common and potentially life-threatening injury in equine veterinary practice. The aim of this study was to systematically analyze data from horses presenting to the clinic with a puncture wound. Unassigned: A retrospective study was conducted on patient data from horses with a puncture wound in the period from September 2008 to August 2024. Analyzed data included medical management and surgical treatment, complications, duration and costs of hospitalization, short-term survival rate and treatment success. Unassigned: A total of 96 horses met the inclusion criteria. Seven ...
Challenges for interpreting results of antimicrobial susceptibility testing for treating infections of foals with Rhodococcus equi.
Equine veterinary journal    August 20, 2026   doi: 10.1002/evj.70312
Seeger MG, Gressler LT, Huber L, Alvarez-Narvaez S, Cargnelutti JF, Bordin AI, Lawhon SD, Cohen ND.Rhodococcus equi is a facultative intracellular pathogen and a major cause of pneumonia in foals worldwide. The standard treatment for affected foals is a combination of a macrolide with rifampicin. The widespread use of this combination has led to the emergence of multidrug-resistant (MDR) strains of R. equi. Consequently, antimicrobial susceptibility testing is essential for guiding treatment of rhodococcal pneumonia. Unfortunately, clinical breakpoints for macrolides and other antimicrobials against R. equi for foals are lacking, thereby complicating clinical interpretation of in vitro resu...
Guttural pouch tympany or empyema in 38 ٍStraight Egyptian Arabian foals: clinical presentation, diagnostic features and outcome.
BMC veterinary research    August 19, 2026   Volume 22, Issue 1 482 doi: 10.1186/s12917-026-05810-3
Abu-Seida AM, Asfour HAE, Abdulredha MAH, Derbala MK.As a breed, Straight Egyptian Arabian horses are susceptible to many disorders that mostly affect the head, such as guttural pouch (GP) tympany and empyema. This retrospective study evaluated the findings of clinical examination, ultrasonography, endoscopy, laboratory analyses and outcome of treatment of 38 Straight Egyptian Arabian foals with GP tympany and empyema. Methods: Data from medical records of foals diagnosed with GP tympany or empyema over a 2-year period (2024-2025) were reviewed. Foals with verified GP tympany or empyema who had complete medical records and had not previously rec...
Epidemiological study of strongyle infections in equines in Egypt: prevalence and risk factors.
Frontiers in veterinary science    August 19, 2026   Volume 13 1901312 doi: 10.3389/fvets.2026.1901312
Selim A, Marzok M, Gattan HS, Alruhaili MH, Ismail H, Almubarak AI, Hereba AM.Equine strongylosis is one of the most prevalent gastrointestinal parasitic diseases affecting horses and donkeys worldwide, leading to reduced health, productivity, and working performance. This study aimed to determine the prevalence of gastrointestinal strongyle infection and identify associated risk factors among equines in three Egyptian governorates. Unassigned: A cross-sectional study was conducted on 540 horses and donkeys. Fresh fecal samples were collected and examined using the magnesium sulfate flotation technique for the detection of strongyle eggs. Associations between infection ...
An experimental multiplex PCR/RT-PCR for detection of the main viruses associated with equine neurological disease.
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]    August 18, 2026   Volume 57, Issue 1 241 doi: 10.1007/s42770-026-02065-w
Scherer SO, Silva Júnior JVJ, Pedroso NH, Dionisio IF, Weiblen R, Flores EF.Viral neurological infections are important causes of morbidity and mortality in horses worldwide. Herein, we describe an end-point multiplex PCR/RT-PCR for simultaneous and differential detection of major equine encephalitis-related agents: rabies virus (RABV), equine herpesvirus type 1 (EHV-1), alphaviruses [Venezuelan equine encephalitis virus (VEEV), Eastern equine encephalitis virus (EEEV), Western equine encephalitis virus (WEEV) and Madariaga virus (MADV)] and flaviviruses [West Nile virus (WNV), Saint Louis encephalitis virus (SLEV), Rocio virus (ROCV) and Japanese encephalitis virus (...
Equine Fungal Keratitis due to Cladorrhinum bulbillosum.
Veterinary ophthalmology    August 17, 2026   Volume 29, Issue 5 e70249 doi: 10.1111/vop.70249
Hamilton A, Lacy L, Scherrer N.To describe the case details and treatment of an equine fungal keratitis case caused by Cladorrhinum bulbillosum. Methods: A 14-year-old Bashkir Curly gelding with a complicated corneal ulcer of the left eye. Methods: Corneal cytology was performed, and intraoperative samples were collected for polymerase chain reaction and for aerobic and mycologic cultures. Under general anesthesia, an inferior eyelid subpalpebral lavage system (SPL) was placed to facilitate postoperative therapy. Anterior stromal keratectomy was performed followed by cryotherapy of the keratectomy bed. A biological scaffold...
Leishmania spp. infection in horses in an endemic area of canine leishmaniosis (north-western Algeria).
Research in veterinary science    August 17, 2026   Volume 211 106365 doi: 10.1016/j.rvsc.2026.106365
Bia T, Marteles-Aragüés D, Sánchez C, Bernardo L, Carrillo E, Solana JC, Manseur H, Zait H, Lafri I, Villanueva-Saz S, Moreno J.Leishmaniosis is a parasitic disease caused by obligate intracellular protozoa of the genus Leishmania. It affects humans, canids, and rodents in endemic areas and is transmitted through the bites of infected sand flies. This study aimed to estimate the prevalence of equine leishmaniosis in horses from Tiaret Province, northwestern Algeria, an area endemic for canine leishmaniosis, and to identify the main risk factors associated with infection. The study included 75 local Barb horses and employed molecular and serological techniques for the detection of Leishmania infection. Among the sampled...
Prevalence, distribution, and associated risk factors of major equine endoparasitic infections in South Gondar Zone, Northwest Ethiopia.
Veterinary and animal science    August 17, 2026   Volume 34 100821 doi: 10.1016/j.vas.2026.100821
Alemayehu H, Alemneh T, Birhan M, Seyoum Z, Baylie M.Endoparasites remain major constraints on equine health and productivity in Ethiopia; however, epidemiological data from northwestern regions are limited. This study investigated the occurrence, parasite diversity, infection intensity, and risk factors associated with endoparasite infections in equines in northwestern Ethiopia. A cross-sectional study was conducted using coprological examinations complemented by postmortem inspections. Standard parasitological techniques were employed, and multivariable logistic regression analysis was used to identify predictors of infection. Data were analyz...
Equine Sarcoid: From BPV-Driven Oncogenesis to Host-Sustained Tumor Persistence.
Pathogens (Basel, Switzerland)    August 14, 2026   Volume 15, Issue 8 847 doi: 10.3390/pathogens15080847
Dell'Anno F, Trebino C, Fruscione F, De Ciucis CG, De Paolis L, Cappelli K, Razzuoli E.Equine sarcoid is the most common cutaneous neoplasm of equids and represents a distinctive model of virus-associated tumor persistence. Although bovine papillomaviruses, particularly BPV-1 and BPV-2, are recognized as the main etiological agents, viral infection alone does not fully explain the clinical heterogeneity, frequent recurrence, and limited spontaneous regression of these lesions. This review summarizes current evidence on the molecular and cellular mechanisms underlying equine sarcoid pathogenesis, with emphasis on the interaction between BPV infection, host signaling pathways, tum...
Failure of Passive Transfer in neonatal foals – a review.
Veterinary journal (London, England : 1997)    August 8, 2026   106818 doi: 10.1016/j.tvjl.2026.106818
Pinto EM, Hurtado LH, Cuervo MM, da Silva CB.Failure of passive transfer (FPT) is a major contributor to morbidity and mortality in neonatal foals worldwide. Adequate ingestion and intestinal absorption of colostral immunoglobulin G (IgG) during the first hours of life are essential to ensure protection against early-life infections, such as diarrhoea and pneumonia, frequently with fatal outcome. This review summarizes current knowledge on the physiology of passive immunization, risk factors for inadequate IgG absorption, diagnostic methods, therapeutic strategies, and evidence-based preventive measures. Recent research highlights the im...
Evaluation of sequential serum amyloid A measurements for the prediction of sepsis and survival in critically ill neonatal foals.
Journal of veterinary internal medicine    August 6, 2026   Volume 40, Issue 4 aalag155 doi: 10.1093/jvimsj/aalag155
de Bruijn E, Pas ML, Castelain D, Dufourni A, Paulussen E, Pardon B.Single measurements of serum amyloid A (SAA) concentration at hospital admission has limited sensitivity for predicting sepsis and death. Objective: To determine whether differences in SAA during the first 2 days of hospitalization could predict sepsis and death in critically ill foals. Methods: One hundred twenty-seven critically ill neonatal foals, <14 days of age. Methods: Prospective cohort study. SAA was measured at hospital admission and on day 2 of hospitalization using a validated point-of-care test. Logistic regression was conducted to evaluate the predictive value of individual S...
Increasing Seroprevalence In Horses Evidences Widespread Circulation Of West Nile Virus In Albania.
Veterinaria italiana    August 6, 2026   Volume 62, Issue 2 doi: 10.12834/VetIt.3956.40757.2
Lufo L, Mersini K, Llorente F, Perez Ramirez E, Jiménez-Clavero MA, Berxholi K.West Nile virus (WNV) is a zoonotic mosquito-borne flavivirus that causes West Nile disease, an emerging and re-emerging infection of major global importance. Horses are an important sentinel species for monitoring WNV circulation. Since viraemia in horses is brief and viral loads in the blood are low, serological assays are the primary tools used to monitor WNV exposure. This study aimed to estimate the seroprevalence of WNV antibodies in horses in Albania. Between 2017 and 2020, 509 serum samples were collected from apparently healthy, unvaccinated horses across different regions of the coun...
Molecular Detection of Anaplasma spp. in Horses From Golestan Province, Northern Iran.
Veterinary medicine and science    August 6, 2026   Volume 12, Issue 5 e71124 doi: 10.1002/vms3.71124
Rad AM, Rahimi H, Changizi E, Staji H.Anaplasmosis is a bacterial zoonotic disease that affects both humans and many animals. In horses, anaplasmosis manifests as a seasonal, infectious, and febrile disease caused by bacteria of the genus Anaplasma. Since the transmission of this disease is primarily mediated by arthropods such as ticks, it holds significant public health importance. Objective: The present study aims to investigate the prevalence of anaplasmosis in horses in northern Iran (Golestan Province). Methods: A total of 350 blood samples were randomly collected from asymptomatic horses between December 2023 and April 2024...
Testicular Disorders in Equids: A Case Series.
Animals : an open access journal from MDPI    August 6, 2026   Volume 16, Issue 15 2439 doi: 10.3390/ani16152439
Catone G, Palmieri V, Giambrone G, Marino G, Magi GE, Mariotti F, Vullo C, Ciccarelli M.Equine testicular disorders represent a diverse group of conditions that impact the longevity of a stallion's breeding career. Stud farm veterinarians should be familiar with the variety of clinical presentations and diagnostic options for these conditions. This retrospective case series reports 57 cases of testicular abnormalities in stallions and donkeys presented to the clinic for further diagnostics and treatment. These disorders included neoplasia (three unilateral and one bilateral seminoma; two Sertoli cell tumors; two Leydig cell tumors; and one malignant mixed sex cord-stromal tumor),...
Risk Factors for Disease in Military Working Equines.
Military medicine    August 6, 2026   Volume 191, Issue Supplement_1 16-21 doi: 10.1093/milmed/usaf625
LaDouceur E, Raynor K, Chilcoat C, Crawford J, Heitz E.Diseases can impact Military Working Equids (MWEs) readiness and limit days in service. The objectives of this study are to categorize diseases in MWEs and evaluate potential risk factors for disease. Methods: Pathology reports from MWEs from 2005 to 2025 were retrieved from the Joint Pathology Center archives. Disease processes with ≥5 cases were evaluated for potential risk factors, including MWE breed, sex, neuter status, geographic location, and age at sampling. Results: Diagnoses included inflammation (n = 30), neoplasia/proliferation (n = 24), within normal limits (n = 12),...
Clinical outcomes of a novel flowable calcium silicate cement in equine endodontic treatment.
Equine veterinary journal    August 5, 2026   doi: 10.1002/evj.70299
Jackson K, Faulkner J, Staszyk C, Ha W, Quintrell E, Kelty E.Orthograde endodontic treatment of equine cheek teeth is performed infrequently with variable success rates of obturation with calcium hydroxide paste (CHP). A novel flowable calcium silicate cement (eCSC) formulated for use as an obturation material in equine teeth has demonstrated acceptable canal filling volumes and evidence of dentinal tubule penetration. However, clinical outcomes of eCSC-obturated equine teeth have not been reported. Objective: To report the clinical outcomes of orthograde endodontic treatment using eCSC. Methods: Retrospective case series. Methods: Horses that underwent...
Evaluation of Serum Specific IgE Sensitization Profiles in a Korean Domestic Horse Population Using a Multiplex Allergen Line-blot Assay: A Cross-Sectional Screening Study.
Journal of equine veterinary science    August 5, 2026   106118 doi: 10.1016/j.jevs.2026.106118
Cho GJ, Jeon J, Eun JK, Almazbek I.The purpose of this study was to evaluate the clinical applicability of a multiplex serum specific Immunoglobulin E (sIgE) test kit 'ANITIA Equine IgE' for identifying the causes of allergic diseases in horses raised in Korea, and to determine the major sensitization antigen profiles in the domestic horse population. Serum or plasma samples were collected from a total of 140 horses, classified by management system (Group A, n=108) and purpose (Group B, n=32). IgE concentrations for 120 environmental and dietary allergens were measured using a multiplex line-blot assay based on an indirect immu...
Rethinking Equine Cystitis: Evidence from Four Atypical Clinical Presentations.
Life (Basel, Switzerland)    August 4, 2026   Volume 16, Issue 8 1285 doi: 10.3390/life16081285
Biazik A, Sobuś M, Henklewski R, Wieteska M, Kordowitzki P.In this case series, four equines were diagnosed with cystitis, resulting in divergent clinical outcomes. Three animals achieved complete clinical resolution without recurrence, whereas one required euthanasia due to progressive clinical deterioration. All diagnoses were established through a dual-modality investigative protocol comprising cystoscopic evaluation and histopathological examination of bladder mucosal biopsies. The cohort exhibited considerable etiological heterogeneity. One case was classified as chronic idiopathic cystitis, while another was attributed to an opportunistic bacter...
Equine Ulcerative Genital Lesions Associated with Parapoxvirus.
Viruses    August 4, 2026   Volume 18, Issue 8 852 doi: 10.3390/v18080852
Cullinane A, Garvey M, Collins D, Lyons R, Nelly M, Grimes A.In 2026, a widespread outbreak of ulcerative dermatitis of unknown aetiology occurred in breeding horses in Ireland. The lesions resembled those associated with equine herpesvirus 3 (EHV3) infection, i.e., papules, vesicles, and ulcers on the penis of stallions and on the vulval and anal areas of mares. This study aimed to identify the probable causative agent. The methods applied included metagenomic sequencing of DNA, phylogenetic analysis, and real-time PCR. Metagenomic analysis directly from a penile sample confirmed the presence of equine parapoxvirus (EqPPV) DNA. Phylogenetic analysis in...
Seroprevalence, risk factors and hematological parameters associated with Equine Infectious Anemia from Casanare, Colombia.
Journal of equine veterinary science    August 3, 2026   106108 doi: 10.1016/j.jevs.2026.106108
Puentes MMM, Guzman YL, Torreglosa JCT, Isaza PAL, Guzman-Barragán BL.Equine infectious anemia (EIA) is a persistent lentiviral disease with important sanitary and economic implications in tropical regions; however, epidemiological information in Colombia remains limited. Objective: To estimate seroprevalence, identify risk factors, and evaluate hematological alterations associated with EIA in horses from Casanare, Colombia. Methods: A cross-sectional study including 1,228 horses from 204 production units across 121 rural districts. Serological diagnosis was performed using agar gel immunodiffusion. Demographic and management data were obtained through an epidem...
Cold Atmospheric Plasma-Aerosol Treatment of Equine Antibiotic-Resistant Wound Infection: A Preliminary Case Series.
Animals : an open access journal from MDPI    August 3, 2026   Volume 16, Issue 15 2380 doi: 10.3390/ani16152380
Kurras S, Conze TM, Obermann S, Fuchs R, Tischendorf T, Knottenbelt DC, Koene M.Wound infections are common sequelae of wound treatment in horses. Secondary bacterial colonization with antimicrobial resistant microorganisms is of particular concern and is of crucial importance regarding the "One Health Concept". Due to frequent antimicrobial resistance (AMR), conventional treatments often involve determining resistance and sensitivity using time-consuming antibiograms. Infections with multi-resistant pathogens are especially challenging. This case series presents studies of four horses evaluating the efficacy of Cold Atmospheric Plasma-Aerosol (CAP-A) as a standalone trea...
Nucleic acid detection and molecular traceability of equine herpesvirus 1 in imported horses.
Frontiers in microbiology    August 3, 2026   Volume 17 1900100 doi: 10.3389/fmicb.2026.1900100
Wang L, Gao Z, Bai Z, Pu J, Shi X, Zhang W, Xu Z, Li Z.Equid alphaherpesvirus 1 is a major pathogen threatening the global equine industry, causing respiratory disease, abortion, and neurological disease. Unassigned: In April 2024, during routine pathogen screening of a batch of imported quarantine horses from the Netherlands, four out of 20 nasal swab samples tested positive for EHV-1 nucleic acid. Unassigned: The affected horses exhibited only mild respiratory signs. ORF30 SNP typing at nucleotide position 2254 and Sanger sequencing confirmed that all positive samples belonged to the N752 non-neuropathogenic genotype. As virus isolation was unsu...