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Topic:Risk Factors

Risk factors in horses refer to variables or conditions that increase the likelihood of disease, injury, or other adverse health outcomes in equine populations. These factors can be intrinsic, such as age, breed, and genetic predisposition, or extrinsic, including environmental conditions, management practices, and exposure to infectious agents. Understanding risk factors is important for developing preventive strategies and improving health management in horses. This page aggregates peer-reviewed research studies and scholarly articles that explore the identification, assessment, and mitigation of risk factors in equine health, with the aim of enhancing disease prevention and promoting overall well-being in horses.
Concussion History, Reporting Behaviors, Attitudes, and Knowledge in Jockeys.
Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine    September 14, 2018   Volume 30, Issue 6 578-584 doi: 10.1097/JSM.0000000000000658
O'Connor S, Warrington G, Whelan G, McGoldrick A, Cullen S.To examine concussion history, knowledge, and attitudes among Irish professional and amateur jockeys. Cross-sectional survey. Questionnaire was distributed through e-mails sent to all licensed jockeys, over social media and during professional and amateur race meetings. An average of 23.6% (12%-44%) Irish professional and amateur jockeys (n = 119) holding a license in 2017. Jockeys reported their previous concussion history, actions after their most recent concussion and responded to questions examining their knowledge and attitudes toward concussion. Amateur (32.4%) and professional (19.6%) j...
Prevalence and risk factors for IgG antibodies to Neospora spp. in three types of equids from Southern Punjab, Pakistan.
Acta tropica    September 13, 2018   Volume 188 240-243 doi: 10.1016/j.actatropica.2018.09.007
Nazir MM, Ayaz MM, Ahmed AN, Rasheed I, Faraz A, Akram Q, Akhtar S, Maqbool A, Tabassum S, Zheng Y, Lindsay DS.Equine hosts suffer from neurological disease, congenital infection, and reproductive problems associated with Neospora spp. infection. We conducted a cross sectional study using sera from 631 equids (324 horses, 218 donkeys and 89 mules) from the southern region of Punjab province, Pakistan to determine the prevalence of antibodies against Neospora spp. in this diverse group of equines. Fisk factors associated with seropositivity were evaluated statistically based on equine type, breed, age, husbandry, breeding methods, and reproductive history. Prevalence of antibodies to Neospora spp. was d...
Relationship Between Historical Lameness, Medication Usage, Surgery, and Exercise With Catastrophic Musculoskeletal Injury in Racehorses.
Frontiers in veterinary science    September 7, 2018   Volume 5 217 doi: 10.3389/fvets.2018.00217
Hitchens PL, Hill AE, Stover SM. The rate of catastrophic musculoskeletal injuries (CMI) in racehorses is high in the United States compared to other countries. Few modifiable risk factors related to lameness, medication, and surgery history have been identified. To detect management factors that increase risk of CMI by comparing medical histories between horses that sustained, and horses that did not sustain, a CMI. Case-control. Racehorse necropsy data (May 2012-June 2013) were obtained through the California Horse Racing Board Postmortem Program. Attending veterinarians of Thoroughbreds (TB) and Quarter Horses (QH) tha...
Comparative seroprevalence and risk factor analysis of Trypanosoma evansi infection in equines from different agro-climatic zones of Punjab (India).
Revue scientifique et technique (International Office of Epizootics)    August 31, 2018   Volume 36, Issue 3 971-979 doi: 10.20506/rst.36.3.2729
Sumbria D, Singla LD, Kumar R, Bal MS, Kaur P.As parasitaemia is low and fluctuating during the chronic stage of infection, accurate detection of Trypanosoma evansi in blood is difficult. The primary aims of this investigation were to assess for the first time the seroprevalence of T. evansi in all agro-climatic zones of Punjab, by indirect enzyme-linked immunosorbent assay (iELISA) and card agglutination test (CATT/T. evansi), and to evaluate the risk factors associated with latent trypanosomosis. A total of 319 equine serum samples collected from 12 districts of Punjab (India) belonging to different agro-climatic zones revealed 39 (12.2...
Prevalence of owner-reported ocular problems and veterinary ocular findings in a population of horses aged ≥15 years.
Equine veterinary journal    August 25, 2018   Volume 51, Issue 2 212-217 doi: 10.1111/evj.13005
Malalana F, McGowan TW, Ireland JL, Pinchbeck GL, McGowan CM.Previous studies suggest that ocular disease is common among aged horses but owners may fail to identify or underestimate their clinical relevance. Objective: To document the prevalence of owner-reported ocular disease in horses aged ≥15 years. In a subset of these horses, to document ophthalmic findings from veterinary examination and compare with owner-reported ocular disease, and to determine risk factors for veterinary ophthalmic findings. Methods: Cross-sectional study. Methods: Owners of aged horses completed a survey on management, clinical signs and medical history. Risk factors for ...
Prevalence of and risk factors for equine glandular and squamous gastric disease in polo horses.
The Canadian veterinary journal = La revue veterinaire canadienne    August 15, 2018   Volume 59, Issue 8 880-884 doi: 10.1186/1751-0147-55-45
Banse HE, MacLeod H, Crosby C, Windeyer MC.The objectives of this study were to determine the prevalence rates and risk factors for equine glandular gastric disease (EGGD) and equine squamous gastric disease (ESGD) in a population of 63 polo horses in competition. The prevalence of EGGD grade ≥ 1 was 69% and EGGD ≥ 2 was 31%. The prevalence of ESGD grade ≥ 1 was 54% and grade ≥ 2 was 37%. The risk factors retained in the final multivariable models were years of experience in polo competition for EGGD grade ≥ 1 and for grade ≥ 2, with decreased experience being associated with EGGD and weekly exercise duration and non-steroi...
Exploratory factor analysis of signalment and conformational measurements in Thoroughbred horses with and without recurrent laryngeal neuropathy.
Equine veterinary journal    August 6, 2018   Volume 51, Issue 2 179-184 doi: 10.1111/evj.12984
McGivney CL, Gough KF, McGivney BA, Farries G, Hill EW, Katz LM.Conflicting results have been reported for risk factors for recurrent laryngeal neuropathy (RLN) based on resting endoscopic evaluation and comparison of single conformation traits, with many traits correlated to one another. Objective: To simplify identification of signalment and conformation traits (i.e. variables) associated with RLN cases and controls diagnosed with exercising overground endoscopy (OGE) using exploratory factor analysis (EFA). Methods: Prospective cohort. Methods: Pearson's rank correlation was used to establish significance and association between variables collected from...
Risk Factors for Transport-Related Problem Behaviors in Horses: A New Zealand Survey.
Animals : an open access journal from MDPI    August 2, 2018   Volume 8, Issue 8 134 doi: 10.3390/ani8080134
Padalino B, Rogers CW, Guiver D, Bridges JP, Riley CB.Transport-related problem behaviors (TRPBs) are common in horses and can cause injury to both the horses and their handlers. This study aimed to identify possible risk factors for TRPBs to inform approaches to mitigate TRPBs incidence and enhance horse welfare. An online cross-sectional survey was conducted to explore the prevalence of TRPBs and their association with human-, training- and transport management-related factors in New Zealand. The survey generated 1124 valid responses that were analyzed using descriptive statistics, and logistic regression analyses. Having at least one horse wit...
Sero-epidemioloical survey on African horse sickness virus among horses in Khartoum State, Central Sudan.
BMC veterinary research    August 1, 2018   Volume 14, Issue 1 230 doi: 10.1186/s12917-018-1554-5
Karamalla ST, Gubran AI, Adam IA, Abdalla TM, Sinada RO, Haroun EM, Aradaib IE.African horse sickness virus (AHSV) is an infectious non contagious insect-transmitted double-stranded (ds) RNA orbivirus of the family Reoviridae. AHSV causes an often fatal hemorrhagic infection with high mortality among selected breeds of Arabian horses. This study was conducted to avail some information with regard to the prevalence and associated risk factors of AHSV among ecotype breeds of horses in central Sudan. Methods: Sera were collected from 320 horses, which were selected randomly from four localities and employed in the study. A competitive enzyme-linked immunosorbent assay (cELI...
Case-control study of risk factors for pasture-and endocrinopathy-associated laminitis in North American horses.
Journal of the American Veterinary Medical Association    July 31, 2018   Volume 253, Issue 4 470-478 doi: 10.2460/javma.253.4.470
Coleman MC, Belknap JK, Eades SC, Galantino-Homer HL, Hunt RJ, Geor RJ, McCue ME, McIlwraith CW, Moore RM, Peroni JF, Townsend HG, White NA....OBJECTIVE To investigate risk factors for the development of pasture- and endocrinopathy-associated laminitis (PEAL) in horses and ponies in North America. DESIGN Case-control study. ANIMALS 199 horses with incident cases of PEAL and 351 horses from 2 control populations (healthy horses [n = 198] and horses with lameness not caused by laminitis [153]) that were evaluated in North America between January 2012 and December 2015 by veterinarian members of the American Association of Equine Practitioners. PROCEDURES North American members of the American Association of Equine Practitioners were co...
Seroprevalence and risk factors of Toxoplasma gondii infection in horses in Jilin Province and Inner Mongolia Autonomous Region, northern China.
Acta tropica    July 30, 2018   Volume 187 119-123 doi: 10.1016/j.actatropica.2018.07.030
Zhang XX, Ren WX, Hou G, Liu Q, Yu TQ, Zhao Q, Ni HB.Toxoplasmosis is caused by the protozoon Toxoplasma gondii that can infect almost all warm-blooded hosts including horses and humans. Horse meat is one of the most important meat products for human consumption. However, data on seroprevalence of T. gondii in horses intended for human consumption in Northern China is scarce. Thus, a total of 614 serum samples were collected from Jilin Province and Inner Mongolia Autonomous Region (IMAR) between 2015 and 2017, and were detected the seroprevalence for T. gondii by indirect hemagglutination assay test. In the prevalence study, the overall seroprev...
Comparison of complication rates following elective arthroscopy performed as inpatient versus outpatient surgery in horses.
Journal of the American Veterinary Medical Association    July 19, 2018   Volume 253, Issue 3 346-354 doi: 10.2460/javma.253.3.346
Secor EJ, Gutierrez-Nibeyro SD, Clark-Price SC, Stewart MC, Kay AT.OBJECTIVE To report complication rates following elective arthroscopy in horses and determine whether postoperative complication rates are higher for outpatient procedures, compared with inpatient procedures. DESIGN Retrospective cohort study. ANIMALS 357 client-owned horses that had undergone 366 elective arthroscopic procedures between January 2008 and February 2015. PROCEDURES Medical records were retrospectively reviewed. Data collected included signalment, travel time to the hospital, clinical signs, joints treated, lesions diagnosed, medications administered, anesthesia and surgery times...
Genetic risk for squamous cell carcinoma of the nictitating membrane parallels that of the limbus in Haflinger horses.
Animal genetics    July 12, 2018   Volume 49, Issue 5 457-460 doi: 10.1111/age.12695
Singer-Berk M, Knickelbein KE, Vig S, Liu J, Bentley E, Nunnery C, Reilly C, Dwyer A, Drögemüller C, Unger L, Gerber V, Lassaline M, Bellone RR.Squamous cell carcinoma (SCC) is the most common cancer affecting the equine eye, with a higher incidence documented in Haflinger horses. Recently, a missense variant in the gene damage specific DNA binding protein 2 (DDB2, p.Thr338Met) on ECA12 was identified as a risk factor for the development of limbal SCC in Haflinger horses. SCC also occurs on the nictitating membrane; therefore, investigating the role of this missense variant in nictitating membrane SCC is warranted. In this study, a common ancestor was identified among Haflinger horses affected with limbal SCC or with nictitating membr...
Prevalence of complications associated with use of the Henderson equine castrating instrument.
Equine veterinary journal    July 12, 2018   Volume 51, Issue 2 163-166 doi: 10.1111/evj.12982
Hinton S, Schroeder O, Aceto HW, Berkowitz S, Levine D.Castration is one of the most common surgical procedures performed in the horse. Complication rate and types of complications associated with use of the Henderson equine castrating instrument have not been determined. Objective: To determine the complication rate and type of complications encountered when using the Henderson equine castrating instrument in equine ambulatory practice. Methods: Retrospective case series. Methods: Medical records of horses undergoing routine castration using the Henderson drill were identified and evaluated for the occurrence of complications. The relationship be...
Epidemiology of race-day distal limb fracture in flat racing Thoroughbreds in Great Britain (2000-2013).
Equine veterinary journal    June 28, 2018   Volume 51, Issue 1 83-89 doi: 10.1111/evj.12968
Rosanowski SM, Chang YM, Stirk AJ, Verheyen KLP.A key focus of the racing industry is to minimise the number of race-day distal limb fractures although no studies have identified risk factors for both fatal and non-fatal distal limb fractures. Objective: To determine risk factors for race-day distal limb fractures experienced by Thoroughbred racehorses participating in flat racing in Great Britain (GB). Methods: Retrospective cohort. Methods: Information was collected from all flat racing starts occurring on GB racecourses between 2000 and 2013, including horse, race, course, trainer and jockey data for each horse start and race-day injury ...
Seroprevalence and associated risk factors of mosquito-borne alphaviruses in horses in northern Queensland.
Australian veterinary journal    June 27, 2018   Volume 96, Issue 7 243-251 doi: 10.1111/avj.12711
Gummow B, Tan R, Joice RK, Burgess G, Picard J.To investigate the seroprevalence and associated risk factors of alphaviruses (Ross River virus (RRV), Barmah Forest virus (BFV) and Whataroa virus (WHAV)) in northern Queensland horses. Methods: A cross-sectional study of alphavirus antibodies in horses (n = 287) from 147 properties in northern Queensland from September 2013 to June 2014 was conducted. Owners of sampled horses were interviewed on potential risk factors. Data were analysed for associations using multivariable logistic regression. Results: Antibody titres for RRV were demonstrated in samples from 134 properties (91%; 95% co...
Equine influenza: evolution of a highly infectious virus.
The Veterinary record    June 22, 2018   Volume 182, Issue 25 710-711 doi: 10.1136/vr.k2727
, and of the equine influenza group at the Animal Health Trust provide a timely reminder of risk of equine influenza and the importance of vaccination.
Can quantitative computed tomography detect bone morphological changes associated with catastrophic proximal sesamoid bone fracture in Thoroughbred racehorses?
Equine veterinary journal    June 1, 2018   Volume 51, Issue 1 123-130 doi: 10.1111/evj.12965
Cresswell EN, McDonough SP, Palmer SE, Hernandez CJ, Reesink HL.Fracture of the proximal sesamoid bones continues to be the most common fatal musculoskeletal injury in US racehorses. Identifying factors that influence fracture risk could lead to screening techniques to reduce catastrophic injury rates and improve animal welfare. Objective: To identify morphological differences between proximal sesamoid bones of the contralateral limb of fracture and control horses and assess the feasibility of computed tomography (CT) to detect traits associated with proximal sesamoid bone fracture. We hypothesised that horses with proximal sesamoid bone fracture would hav...
Risk factors associated with strongylid egg count prevalence and abundance in the United States equine population.
Veterinary parasitology    May 31, 2018   Volume 257 58-68 doi: 10.1016/j.vetpar.2018.05.006
Nielsen MK, Branan MA, Wiedenheft AM, Digianantonio R, Scare JA, Bellaw JL, Garber LP, Kopral CA, Phillippi-Taylor AM, Traub-Dargatz JL.Equine strongyle parasites are considered ubiquitous in grazing equids across the world, and cyathostomin parasites are known pathogens causing well-described disease complexes in horses. Decades of intensive anthelmintic treatments have led to anthelmintic resistance in cyathostomins, and current recommendations are to lower treatment intensity and base control strategies on fecal egg count surveillance. Little is known about risk factors associated with strongyle parasite egg shedding patterns in the United States equine population, as the most recent national survey was conducted 20 years a...
Endocrine Disorders of the Equine Athlete.
The Veterinary clinics of North America. Equine practice    May 29, 2018   Volume 34, Issue 2 299-312 doi: 10.1016/j.cveq.2018.04.003
Frank N.Equine athletes are affected by 2 major endocrine/metabolic disorders, insulin dysregulation (ID) and pituitary pars intermedia dysfunction. ID is a risk factor for laminitis in horses, which poses the greatest threat to performance because of the damage that it causes to hoof structures. This article includes an in-depth discussion of ID and other risk factors for laminitis that are grouped together as equine metabolic syndrome. As horses age, the risk of pituitary pars intermedia dysfunction increases, and this endocrine disorder may exacerbate preexisting ID and further increase the risk of...
Universities should encourage helmet wearing.
The Veterinary record    May 26, 2018   Volume 182, Issue 21 607 doi: 10.1136/vr.k2259
Whitbread H.No abstract available
Risk Factors Associated With Seroreactivity Against Leptospira sp. in Horses From Brazilian Amazon.
Journal of equine veterinary science    May 22, 2018   Volume 68 59-62 doi: 10.1016/j.jevs.2018.05.197
Peixoto Ribeiro TM, Correia L, Hofstaetter Spohr KA, Aguiar DM, Martins G, de Sá Jayme V.This study investigated the risk factors associated with seroreactivity to Leptospira sp. in horses from Brazilian Amazon. Blood samples were collected and microscopic agglutination test was performed, and univariate and multivariate analyses were conducted for association with risk factors. General seroprevalence was 32.7% and the most prevalent serogroup observed was Sejroe (5.9%). Seroreactivity was associated with age, sex, activity (work, leisure, or both), feed supplementation, trash accumulation, and presence of felines. Epidemiology of leptospirosis remains poorly understood in Amazon ...
Respiratory disease and sero-epidemiology of respiratory pathogens in the working horses of Ethiopia.
Equine veterinary journal    May 17, 2018   Volume 50, Issue 6 793-799 doi: 10.1111/evj.12834
Laing G, Christley R, Stringer A, Aklilu N, Ashine T, Newton R, Radford A, Pinchbeck G.Pathogens are frequently implicated in equine respiratory disease. In Ethiopia, respiratory disease is a frequent cause for presentation at veterinary clinics and a priority concern for users of working horses. However, there is little existing literature on possible aetiologies. Objective: Determine prevalence of respiratory signs and exposure to major respiratory pathogens through a serological survey. Methods: Cross-sectional. Methods: Systematically selected horses from 19 sites in central Ethiopia were examined clinically and sampled once (August-December 2013). A face-to-face interview c...
Conjugated equine estrogen and medroxyprogesterone acetate are associated with decreased risk of breast cancer relative to bioidentical hormone therapy and controls.
PloS one    May 16, 2018   Volume 13, Issue 5 e0197064 doi: 10.1371/journal.pone.0197064
Zeng Z, Jiang X, Li X, Wells A, Luo Y, Neapolitan R.By the 1990s it became popular for women to use hormone therapy (HT) to ease menopause symptoms. Bioidentical estrogen and progesterone are supplements whose molecular structures are identical to what is made in the human body, while synthetic supplements are ones whose structures are not. After the Women's Health Initiative found that the combined use of the synthetics conjugated equine estrogen (CEE) and medroxyprogesterone acetate (MPA) increased breast cancer risk, prescriptions for synthetic HT declined considerably. Since then there has been an increased interest in bioidentical HT; toda...
Risk factors for equine glandular and squamous gastric disease in show jumping Warmbloods.
Equine veterinary journal    May 12, 2018   Volume 50, Issue 6 747-751 doi: 10.1111/evj.12949
Pedersen SK, Cribb AE, Windeyer MC, Read EK, French D, Banse HE.Prevalence of, and risk factors for, equine squamous gastric disease (ESGD) are well established. Limited data exists on risk factors for equine glandular gastric disease (EGGD). Objective: To identify management factors associated with EGGD in show jumping Warmbloods in training. A secondary objective was to identify management factors associated with ESGD. Methods: Cross-sectional. Methods: Gastroscopies were performed in horses following a 12-16 h fast. Management questionnaires were collected for each horse. Risk factors were determined using multivariable logistic regression modelling. Re...
All equine vets should wear helmets.
The Veterinary record    May 8, 2018   Volume 182, Issue 18 521 doi: 10.1136/vr.k1982
Shaw L. argues that, due to the equine profession having the highest injury rate of all civilian professions, senior veterinary surgeons should take the lead in wearing helmets as routine.
Validation of a Risk Index Model for Predicting Eastern Equine Encephalitis Virus Transmission to Horses in Florida.
Journal of medical entomology    May 4, 2018   Volume 55, Issue 5 1143-1149 doi: 10.1093/jme/tjy067
Downs J, Vaziri M, Jenkins A, Unnasch T.Eastern Equine Encephalitis Virus (EEEV) is the most pathogenic arbovirus endemic to the United States. EEEV primarily infects birds but can be fatal to humans, horses, and some other mammals. Although EEEV transmission occurs in the Northeastern, Southeastern, and Midwestern United States, the largest number of horse and human cases have been reported in Florida, the only state where transmission occurs year round. Currently, a GIS-based risk index (RI) model is used to map EEE transmission risk to horses in Florida. This study validates that RI model using a 5-yr dataset of horse cases in Fl...
Risk factors associated with clinical signs of vesicular stomatitis and seroconversion without clinical disease in Colorado horses during the 2014 outbreak.
Preventive veterinary medicine    May 2, 2018   Volume 156 28-37 doi: 10.1016/j.prevetmed.2018.05.002
Urie NJ, Lombard JE, Marshall KL, Digianantonio R, Pelzel-McCluskey AM, McCluskey BJ, Traub-Dargatz JL, Kopral CA, Swenson SL, Schiltz JJ.Vesicular stomatitis (VS) is caused by a contagious rhabdovirus that affects horses, cattle, and swine. Clinical signs of vesicular stomatitis virus (VSV) infection in pigs and cattle are indistinguishable from foot-and-mouth disease (FMD), a foreign animal disease and reportable disease in the United States (Rodriguez et al., 2000). A VS epidemic occurred in the Rocky Mountain region in 2014-15. A study was conducted in Colorado to evaluate horse- and management-level factors associated with VS. For a horse to be considered a clinical VS horse, there were two requirements. First, clinical VS ...
Fédération Equestre Internationale endurance events: Risk factors for failure to qualify outcomes at the level of the horse, ride and rider (2010-2015).
Veterinary journal (London, England : 1997)    April 23, 2018   Volume 236 44-48 doi: 10.1016/j.tvjl.2018.04.011
Bennet ED, Parkin TDH.An epidemiological study of elite endurance riding was conducted using data from every Fédération Equestre Internationale (FEI) endurance event from 2010 to 2015, comprising 82,917 starts. The aim of the study was to identify risk factors associated with failure to qualify outcomes for horses during FEI endurance rides. The FEI endurance rules state that, during a ride, horses must be assessed by veterinarians several times, giving veterinarians the opportunity to prevent those horses exhibiting signs of lameness or metabolic problems from continuing further. Multivariable logistic regressio...
Fédération Equestre Internationale (FEI) endurance events: Riding speeds as a risk factor for failure to qualify outcomes (2012-2015).
Veterinary journal (London, England : 1997)    April 22, 2018   Volume 236 37-43 doi: 10.1016/j.tvjl.2018.04.012
Bennet ED, Parkin TDH.This study examined the association between riding speed and elimination in Fédération Equestre Internationale (FEI) endurance events. A total of 35,061 horse starts from 1st July 2012 to 31st December 2015 were included in a multivariable logistic regression model containing 25 different risk factors. Riding speeds in individual stages ('loops') were included as individual risk factors in studying the progress of horses through loops 1-3 of each endurance ride. The possibility of real-time, 'mid-ride' predictive modelling was explored by modelling both riding speeds and sudden changes in sp...
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