Veterinary care in horses encompasses the medical and preventive measures taken to maintain and improve the health and well-being of equine patients. It includes a wide range of practices such as routine health examinations, vaccinations, dental care, parasite control, and management of injuries and diseases. Veterinary care also involves diagnostic procedures, surgical interventions, and therapeutic treatments tailored to the specific needs of horses. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of equine veterinary care, including advancements in diagnostic techniques, treatment protocols, and health management strategies to support the well-being and performance of horses.
van der Merwe LM, Schliewert EC.Colic is a common equine emergency requiring medical or surgical intervention. These interventions can be costly, making outcomes data and prognostic indicators essential for guiding referral and treatment decisions. Objective: To determine survival rates to hospital discharge and evaluate prognostic indicators in equine colic cases treated at a referral hospital (Onderstepoort Veterinary Academic Hospital [OVAH], South Africa). Methods: This retrospective observational cohort study analysed records from horses with colic that were presented to the OVAH from January 2019 to August 2021. Data i...
Griessel TS, Muñoz Morán JA, Byaruhanga C, Smit Y.Surgical site infection (SSI) is a significant cause of postoperative morbidity following equine laparotomy. Therefore, if risk factors for SSI can be identified, morbidity may consequently be reduced. The objectives of this study were to determine the prevalence of SSI in horses undergoing exploratory laparotomy at a single hospital over an 8-year period (2013‒2021), investigate the risk factors associated with SSI and report on the bacterial isolates identified. Methods: The medical records of horses that had an exploratory laparotomy performed at the teaching hospital due to colic were r...
Contino EK.Long before the concept of social license to operate came to the forefront of equestrian sports, veterinarians have always had a responsibility to advocate for the welfare of the horse. For performance horses this often means helping to ensure that the horse is performing positively and comfortably for its intended use. A horse that is struggling to perform at an optimal level may be doing so for a multitude of reasons, but regardless of the underlying cause, it often presents as any number of behavioral issues. This review explores various underlying physical causes of behavioral issues in pe...
Connaughton MT, MacDonald EJ, Ireland JL, Rocchigiani G, Stack JD.Caudal wedge ostectomy has not been investigated for overriding or impinging spinous processes (SPs). Objective: To establish the feasibility of caudal wedge ostectomy and compare measures of surgical trauma and error between hypothetical caudal and cranial wedge ostectomies on SPs of different inclinations. Methods: Experimental, method comparison study. Methods: Computed tomography and caudal wedge ostectomy surgery were performed on four cadavers. Observations, technical difficulties, and surgical errors were recorded. Radiographs from 67 horses with overriding/impinging SPs were reviewed. ...
de Secondi C, Cantatore F, Marcatili M, Biggi M, Withers J, de Zani D, Zani D.Back pain is a debilitating condition hampering horses' athletic careers. Thoracic spondylosis (TS), a known cause of back pain, leads to osteophytes formation across intervertebral joints. In horses, TS is poorly reported, with anecdotal signs and response to treatment. To report clinical presentation, diagnostic imaging findings, treatment and outcome in horses with TS. The clinical records of horses diagnosed with TS between 2010 and 2023 were reviewed. Signalment, clinical and imaging findings, treatment, and outcome were analysed. Thoracic spondylosis was graded from 1 to 5. Grades, concu...
Fischetti L, Perina F, Sarli G, Ellero N, Freccero F, Castagnetti C, Mariella J.A 286-day pregnant mare was referred for signs of impending abortion. The ultrasonographic evaluation revealed a high normal combined thickness of the utero-placental unit (CTUP), oligohydroallantois and a living fetus. No vulvar discharge was observed, and the cervical swab culture was negative. After a choke, the mare received NSAIDs and antibiotics and then developed systemic inflammatory response syndrome (SIRS) and aborted. The amniotic portion of the umbilical cord was excessively long and twisted and the chorionic side of the placenta showed a brown discoloration and rough surface area....
Wilkins PA, Wong D, Slovis NM, Collins N, Barr BS, MacKenzie C, De Solis CN, Castagnetti C, Mariella J, Burns T, Perkins G, Delvescovo B, Sanchez LC....Sepsis has been defined in humans as the concurrent proven or suspected presence of microbial infection and the systemic inflammatory response syndrome (SIRS). Sepsis is the leading cause of morbidity and mortality in neonatal foals. The clinical utility of using SIRS or its individual components to predict infection and mortality in critically ill foals is currently unknown. Objective: Assess the ability of history and signalment, clinical findings, laboratory results, and SIRS-related indices to predict infection and mortality in critically ill foals. Methods: Retrospective, multi-center, cr...
Bindi F, Nocera I, Meucci V, Vallesi G, Sala G, Spadari A, Rinnovati R, Bonelli F, Sgorbini M.This study investigated the plasma concentrations of symmetric dimethylarginine (SDMA) and asymmetric dimethylarginine (ADMA) in healthy horses and in horses affected by colic in relation to the type of colic and systemic inflammation response syndrome (SIRS) status. Upon admission (T0), horses underwent a physical examination, and the SIRS status was assessed. The horses with colic were divided retrospectively based on the type of colic, SIRS status, treatment, and outcome. SDMA and ADMA levels were measured at T0 and then every 24Â h at four time points (T1, T2, T3, T4). Differences between ...
Cullinane A, Nelly M, Dayot L, Lukaseviciute G, Garvey M, Healy J, Gallagher R.This study describes a comparison of the detection of rotavirus in clinical samples from foals using two commercially available rapid antigen detection (RAD) kits, with the detection of rotavirus nucleic acid via a laboratory-based, in-house, real-time reverse transcription polymerase chain reaction (RT-PCR) assay. One hundred and forty freeze-thawed samples (70 that were RT-PCR-positive and 70 that were RT-PCR-negative on original tests) submitted to the diagnostic laboratory over a seven-year period were tested in addition to 123 fresh samples (15 RT-PCR-positive and 108 RT-PCR-negative) sub...
Rosse NDS, Tavares RA, Nunes MC, de Freitas BW, Reis ECC.Early detection of renal deficient function is imperative for the success of treatments and determining prognosis. In horses, a renal ultrasound can be performed through the abdominal wall (TA) or transrectally (TR), being an important tool for the evaluation of the kidneys. Besides renal morphology, resistivity (RI) and pulsatility indexes (PI) may be early tools to detect renal injury as they reflect arterial compliance. Twenty-nine healthy adult horses were sonographically evaluated by TA and TR approaches, measuring RI and PI on both kidneys. The mean values from the TA for RI and PI in th...
Jastrzębska E, Górecka-Bruzda A, Ogłuszka M, Lipka MS, Pawłowska A.This pilot study investigated the effects of massage therapy on stress indicators in recreational horses, focusing on salivary cortisol levels, heart rate and conflict behaviors. Five recreational horses were analyzed under two experimental conditions: without and with massage treatments before riding sessions. Saliva samples were collected at four specific intervals in each condition to measure cortisol concentrations using an ELISA test. Observations of behavioral indicators and heart-rate monitoring complemented the physiological data. The results revealed that massage significantly reduced...
Asai Y, Tsunetoshi Y, Susa Y, Matsuzawa A, Miyazaki S, Itagaki Y, Yamamoto H, Kimura K, Kushiya H, Sato S, Okada N, Yamabuki T, Kato K, Kinoshita Y....Horse kicks are a rare cause of injury and tend to cause severe complications such as visceral organ injury. Traumatic duodenal injuries are associated with high mortality rates. Furthermore, their reconstructive procedures vary widely and require appropriate on-the-spot judgment by the surgeon. We experienced a case of blunt abdominal trauma with a complete transection of the first portion of the duodenum caused by a horse kick without any associated lesions. A good postoperative course was achieved by trimming the pyloric part of the stomach and performing an end-to-end anastomosis between t...
Woods TDC, Dixon J, Fraser BSL, Melvaine C.Exploratory tenoscopy is considered the gold standard technique to identify intrathecal pathology of the equine carpal flexor tendon sheath (CFTS). Preoperative diagnosis allows for more precise prognostication and surgical planning, potentially associated with improved surgical outcomes. This prospective, descriptive, anatomical study aimed to describe the anatomy of the equine CFTS using noncontrast and contrast CT in clinically normal cadaver limbs. Ten pairs of equine forelimbs free of gross external abnormalities were examined from mid-antebrachium to distal metacarpus. Specimens initiall...
Yamaga T, Tagami M, Takeyama A, Kato F, Suzuki T, Tagami M, Tsuzuki N.Computed tomography (CT) offers high-resolution, three-dimensional imaging, making it particularly valuable for assessing complex structures, such as the head, especially when conventional radiography and endoscopy are insufficient for a definitive diagnosis. Herein, we present two cases of equine cranial disorders resulting from congenital malformations. In case 1, which had a dentigerous cyst, CT images confirmed the location of the ectopic tooth within the skull and a detailed fistula tube. In case 2, which had temporohyoid osteoarthropathy, CT examination revealed that the stylohyoid bone ...
Gorenberg EB, Slack J, Stefanovski D, Theiss D, Hopster K.Dobutamine is a first-line therapy for hypotension in anaesthetised horses, but the effects on haemodynamic parameters in standing and anaesthetised horses are not well studied. Objective: To investigate the effects of dobutamine in escalating dosages on haemodynamic performance in awake and anaesthetised horses. Methods: Randomised cross-over experimental study. Methods: Six healthy adult horses were enrolled, including both standing and isoflurane-anaesthetised experiments with 1-week washout. Heart rate, mean arterial pressure (MAP), central venous pressure, pulmonary arterial pressure, and...
Vall E, Blanchard M, Sib O, Cormary B, González-GarcÃa E.In tropical regions, subject to significant fluctuations in feedstuffs, the body condition score (BCS) is a relevant indicator for monitoring body reserves status of farm animals. However, the most used BCS grids comes from temperate conditions and still not adapted for tropical species, which limits adoption and usefulness. The current work presents for the first time an original, low-cost, standardized BCS assessment system, suited to a large spectrum of tropical farm animals (zebu and/or crossbred cattle, buffaloes, camel, sheep, goats, horses and donkeys). Based on a rigorous set of unifor...
Loublier C, Costa M, Taminiau B, Lecoq L, Daube G, Amory H, Cesarini C.Research on fecal microbiota changes during hospitalization of horses with colic is emerging. Objective: Describe changes of the fecal microbiota during hospitalization of horses with colic caused by inflammatory (INFL), simple (SIMPLE), and strangulated (STR) obstructions, and investigate associations with survival. Methods: Twenty-three horses with colic: 9 in INFL, 5 in STR, and 9 in SIMPLE groups. Seventeen horses survived, and 6 were euthanized. Methods: Prospective observational study. Fecal samples were collected on admission (D1), on days 3 (D3) and 5 (D5). Bacterial taxonomy profiling...
Munerato MS, Simon O, Nicholson A.This report describes successful cardiopulmonary resuscitation of a healthy, 525 kg, 8 years 9 months-old Quarter horse gelding. After successful pelvic limb orthopaedic surgery to excise a metatarsal bone under general anaesthesia, with the horse in left lateral recumbency, the horse was hoisted into recovery. After the horse was positioned in recovery, a routine cardiac check by thoracic auscultation was performed. Cardiopulmonary arrest (CPA) was identified by absence of cardiac sounds and pulse, as evaluated by digital palpation of the facial artery, absence of the right palpebral reflex, ...
Oyaneder L, Lagos N, Dörner C.The present study was conducted to evaluate the safety and the long-lasting anesthetic properties of Neosaxitoxin (NeoSTX) when injected into the intercoccygeal space in standing horses. A group of eighteen (n = 18) healthy client-owned mature crossbreed horses were enrolled in this study. Caudal epidural injection was ascertained by two methods, the "hanging drop" technique and radiographs. Horses were allocated into three groups (n = 6) each group receiving different dosages of NeoSTX. To assess the onset of action and duration of anesthesia, six horses received 20 μg in 2 mL, six 20Â...
Mota-Rojas D, Whittaker AL, Coria-Avila GA, MartÃnez-Burnes J, Mora-Medina P, DomÃnguez-Oliva A, Hernández-Avalos I, Olmos-Hernández A....The growing interest in managing and recognizing pain in animals has led to the search for more sensitive methods to evaluate it, especially because some species conceal any visible changes associated with pain or are not easily assessed. Research has shown that an animal's facial expression changes when exposed to painful stimuli. Thus, developing several pain scales (grimace scales) in species such as horses, cattle, pigs, sheep, donkeys, rabbits, rats, mice, and cats has helped to improve the study of pain in veterinary medicine. The possibility of using facial expression as an indicator of...
Penazzi L, Pagliara E, Nervo T, Ala U, Bertuglia A, Romano G, Hattab J, Tiscar PG, Bergagna S, Pagliasso G, Antoniazzi S, Cavallarin L, Valle E....Foals commonly experience diarrhoea in the first weeks of life. Although this condition is rarely life-threatening, it can have significant health consequences. This study investigated whether new-born foals can benefit from a dietary supplement of nucleotides, as already demonstrated in other species. Dietary nucleotides have positive effects on rapidly proliferating tissues and are considered "semi-essential nutrients" since cells have only a limited capacity to synthesize these compounds. The aim of this study was to investigate whether providing foals with a dietary nucleotide supplementat...
Albanese V, Straticò P, Fischer H, Petrizzi L.Injuries to the distal limb are common in horses. The clinical aspect of the lesions is variable based on the structures that are involved. Synovial structures as well as tendons and/or ligaments may be involved in such injuries, affecting treatment modalities and costs, and prognosis. This retrospective study compares wounds involving synovial structures to wounds without such involvement in terms of treatment duration and costs, and prognosis. Synovial wounds were much more expensive to treat and carried a lower prognosis. Involvement of tendons and/or ligaments in the wounds resulted in mor...
Cameron A, Geldard M, Mair T, England G, Burford J, Freeman S, Pollock K, Wilson E.Veterinary and charity teams are frequently involved in equine end-of-life decisions. These can cause ethical dilemmas and emotional burdens and complicate communication with owners. Semi-structured focus groups explored experiences of making decisions about end-of-life care and euthanasia at three UK equine veterinary practices and one charity. There were 26 participants in a mix of roles. Inductive coding was conducted during thematic analysis. Major themes generated were 'Equine Welfare', 'Relationships', 'Decision-Making', and 'Emotional Toll and Coping Strategies'. Communication, finances...
Hardefeldt LY, Thomas K, Begg L.Antimicrobial resistance (AMR) is a problem for equine practitioners in Australia, but antimicrobial use in practice has been largely understudied. We aimed to evaluate equine veterinarians' intentions of prescribing antimicrobials in areas where we perceived there to be wide ranges of practice - dentistry, reproduction and for nonbactericidal effects. Methods: An online cross-sectional survey of veterinarians working in equine practice was conducted over 4 months in 2023 and 2024. Antimicrobial use, including compounding practices, for reproductive and dental disorders, and nonbactericidal...
McCarthy RD, Ordóñez HJ, Semevolos SA.To compare core temperatures of superficial and deep digital flexor tendons (SDFT, DDFT) during application of a compression cooling system versus ice boots and during subsequent lower limb bandaging. Methods: Experimental study. Methods: Paired forelimbs of six sedated horses. Methods: Thermocouples were placed in the core of SDFT and DDFT of both front limbs of each horse. A compression cooling system was applied to one front limb and an ice boot was applied to the other front limb for 60 min and then removed for 60 min. Standing bandages were then applied to both front limbs for 60 mi...
Júnior GS, de Souza JV, de Souza Ferreira W, Florentino VRD, Valente TC, Comassetto F, Oleskovicz N.This study aimed to evaluate the sedation degree, cardiopulmonary effects, and detomidine-sparing during dental occlusal adjustment in standing horses using a bolus and constant rate infusion (CRI) of detomidine alone or in combination with butorphanol or methadone. In this randomized, blinded clinical trial, 24 healthy adult horses were assigned to the detomidine (DT), detomidine-butorphanol (DB), or detomidine-methadone (DM) group. DT received an intravenous bolus of detomidine (20 μg/kg), followed by CRI at 20 μg/kg/h. DB received detomidine (10 μg/kg) and butorphanol (0.02 mg/kg) boluse...
Aldayarov N, Tulobaev A, Madumarov A, Risvanli A.While modern veterinary medicine offers effective treatments, traditional ethnoveterinary practices persist among many farming communities, reflecting centuries-old knowledge and cultural beliefs. This study aimed to document ethnoveterinary remedies and their methods of preparation and application, for treating various parasitic diseases in domestic animals used by Kyrgyz farmers. Data on plant, animal and mineral-based remedies, as well as chemicals used for these purposes, were collected through interviews with 173 dialogue partners (DPs). A total of 3403 use reports (URs) were recorded, in...
Branda F, Yon DK, Albanese M, Binetti E, Giovanetti M, Ciccozzi A, Ciccozzi M, Scarpa F, Ceccarelli G.Equine influenza (EI) is a highly contagious respiratory disease caused by the equine influenza virus (EIV), posing a significant threat to equine populations worldwide. EIV exhibits considerable antigenic variability due to its segmented genome, complicating long-term disease control efforts. Although infections are rarely fatal, EIV's high transmissibility results in widespread outbreaks, leading to substantial morbidity and considerable economic impacts on veterinary care, quarantine, and equestrian activities. The H3N8 subtype has undergone significant antigenic evolution, resulting in the...
Sijtsema M, Stringer T, Hopman NEM, van der Graaf-van Bloois L, Duim B, van den Brom-Spierenburg A, Theelen M, Zomer A, Broens EM.Healthcare-associated infections (HAIs) associated with ESKAPEE pathogens are an emerging concern in equine hospitals, especially in the intensive care unit (ICU). To gain insight into the occurrence of HAIs and to identify potential reservoirs and transmission routes of ESKAPEE pathogens in an equine ICU, a pilot study of two periods (December 2022-January 2023 and April-June 2023) was performed, where patient and environmental samples were obtained upon ICU admission and discharge. A sampling and laboratory protocol for the detection and identification of different ESKAPEE pathogens and Salm...
Mesenchymal stem cells (MSCs) offer promise as therapeutic aids in the repair of tendon and ligament disorders in sport horses. Equine allogeneic MSCs derived from umbilical cord blood (eUCB-MSCs) can be obtained in a minimally invasive fashion with successful propagation of MSCs. Objective: The objective of this study was to determine the applicability and therapeutic effect of eUCB-MSCs on tendinitis of the superficial digital flexor tendon, desmitis of the suspensory ligament, tendinitis of the deep digital flexor tendon, and desmitis of the inferior check ligament in clinical cases. Method...
In 2001, West Nile virus (WNV) activity was reported from 359 counties in 27 states and the District of Columbia (DC) to ArboNET, a web-based, surveillance data network maintained by 54 state and local public health agencies and CDC. This activity represented a marked increase from 2000, when WNV activity was reported from 138 counties in 12 states and DC. This report summarizes surveillance data for 2001, which indicate that 66 human illnesses were reported from 10 states and that widespread WNV activity in birds, horses, and mosquitoes extended into the midwestern United States and several s...
Cortinovis C, Caloni F.Alkaloids, nitrogen-containing secondary plant metabolites, are of major interest to veterinary toxicology because of their occurrence in plant species commonly involved in animal poisoning. Based on epidemiological data, the poisoning of cattle and horses by alkaloid-containing plants is a relatively common occurrence in Europe. Poisoning may occur when the plants contaminate hay or silage or when forage alternatives are unavailable. Cattle and horses are particularly at risk of poisoning by Colchicum autumnale (meadow saffron), Conium maculatum (poison hemlock), Datura stramonium (jimson wee...
Tamzali Y, Borde L, Rols MP, Golzio M, Lyazrhi F, Teissie J.Sarcoids are the commonest form of equine skin tumour. Several therapeutic measures have been described but none is considered to be universally effective. Electrochemotherapy (ECT) is a new anticancer therapy that utilises electrical field pulses to induce increased cell membrane permeability to antitumour hydrophilic drugs, such as cisplatin. The increased intracellular concentration of the drugs has a significant therapeutic benefit. The procedure has not been previously reported in a large number of horses. Objective: To validate ECT as a novel alternative treatment for equine sarcoids. Me...
Geburek F, Roggel F, van Schie HTM, Beineke A, Estrada R, Weber K, Hellige M, Rohn K, Jagodzinski M, Welke B, Hurschler C, Conrad S, Skutella T....Adipose tissue is a promising source of mesenchymal stromal cells (MSCs) for the treatment of tendon disease. The goal of this study was to assess the effect of a single intralesional implantation of adipose tissue-derived mesenchymal stromal cells (AT-MSCs) on artificial lesions in equine superficial digital flexor tendons (SDFTs). During this randomized, controlled, blinded experimental study, either autologous cultured AT-MSCs suspended in autologous inactivated serum (AT-MSC-serum) or autologous inactivated serum (serum) were injected intralesionally 2Â weeks after surgical creation of cen...
Raabe O, Shell K, Fietz D, Freitag C, Ohrndorf A, Christ HJ, Wenisch S, Arnhold S.Mesenchymal stem cells have become extremely interesting for regenerative medicine and tissue engineering in the horse. Stem cell therapy has been proven to be a powerful and successful instrument, in particular for the healing of tendon lesions. We pre-differentiated equine adipose-tissue-derived stem cells (ASCs) in a collagen I gel scaffold by applying tensile strain, growth differentiation factors (GDFs) and various oxygen tensions in order to determine the optimal conditions for in vitro differentiation toward the tenogenic lineage. We compared the influence of 3% versus 21% oxygen tensio...
Bidwell LA, Bramlage LR, Rood WA.To determine the fatality rate of horses undergoing general anaesthesia at a private equine referral practice using a limited number of anaesthetic protocols. Methods: A retrospective analysis of records (n = 17 961) from all horses undergoing general anaesthesia for surgical procedures from 1997 to 2001 at Rood and Riddle Equine Hospital, Lexington, Kentucky, USA. Results were reported as percentage of the population, and as crude mortality rates for each procedure (deaths per 1000). Results: The prevalence of equine fatalities directly related to anaesthesia was 0.12% (n = 21) and this rose ...
Pollock PJ, Prendergast M, Schumacher J, Bellenger CR.The serum concentrations of serum amyloid A, haptoglobin and fibrinogen were measured in a group of horses before and at intervals after elective and non-elective surgery, and in a control group of normal horses. There was a significant, rapid and repeatable increase in the concentration of serum amyloid A in response to both elective and non-elective surgery. In the control horses its serum concentration was within the normal range, from 0 to 0.2 microg/ml. Twenty-four hours after elective surgery its mean peak concentration was 16.4 microg/ml, and after non-elective surgery it was 27.3 micro...
Belgrave RL, Dickey MM, Arheart KL, Cray C.To compare serum amyloid A (SAA) concentration, plasma fibrinogen concentration, total WBC count, and serum albumin-to-globulin concentration ratio (A:G ratio) in clinically normal (CN) and clinically abnormal (CA) horses. Methods: Prospective cohort study. Methods: 111 CN horses and 101 CA horses hospitalized at a specialty clinical practice. Methods: Shortly after admission, a blood sample (20 mL) was collected from each horse for a CBC, serum protein electrophoresis, and determination of plasma fibrinogen concentration; SAA concentration was assessed with a previously validated immunoturbid...
Schwarz S, Roberts MC, Werckenthin C, Pang Y, Lange C.A total of 838 staphylococcal isolates representing 19 different species were obtained from cattle, cats, dogs, ducks, guinea pigs, horses, mink, pigeons, pigs, rabbits, and turkeys. From these 228 (27.2%) isolates were shown to be resistant to tetracycline and to carry one or two of the tetracycline resistance (tet) genes tet (K), tet (L), tet (M), or tet (O) with seven different distribution patterns. Additional resistances to one or more antibiotics were observed in 153 (67.1%) of the tetracycline resistant isolates. The tet (M) gene was found in 94.3% of the resistant S. intermedius isolat...
Yondon M, Heil GL, Burks JP, Zayat B, Waltzek TB, Jamiyan BO, McKenzie PP, Krueger WS, Friary JA, Gray GC.Equine influenza virus (EIV) epizootics affect 2.1 million Mongolian horses approximately every 10 years and critically impact economy and nomadic livelihood of Mongolia. Objective: An active surveillance program was established in 2011 to monitor influenza viruses circulating among Mongolian horses. Methods: Nasal swabs were collected from horses in free-ranging horse herds in Töv, Khentii, and Dundgovi aimags (provinces) from January to September 2011. Real-time reversetranscriptase-polymerase chain reaction (rRT-PCR) was used to determine the presence of influenza A virus. Influenza A-posi...
Pozor MA, McDonnell SM.The objectives of this study were to evaluate the potential use of color Doppler ultrasound to characterize blood flow to the stallion testis, and to establish reference values for Doppler measures of blood flow in the testicular artery of the stallion. Both testes from each of 52 horses were examined using a pulsed-wave color Doppler ultrasound with a sector array 5/7.5 MHz transducer with a 1mm gate setting. Peak systolic velocity (PSV), end diastolic velocity (EDV), resistive index (RI), and pulsatility index (PI) of the testicular artery were measured in each of two locations, the convolut...
Kern A, Perreten V.To determine the antibiotic resistance and fingerprint profiles of methicillin-resistant coagulase-negative staphylococci (MRCoNS) from animal infections among different practices and examine the history of antibiotic treatment. Methods: Isolates were identified by mass spectrometry and tested for antimicrobial resistance by broth dilution, microarrays and sequence analysis of the topoisomerases. Diversity was assessed by PFGE, icaA PCR and staphylococcal cassette chromosome mec (SCCmec), arginine catabolic mobile element (ACME) and multilocus sequence typing. Clinical records were examined re...
Giannitti F, Diab S, Mete A, Stanton JB, Fielding L, Crossley B, Sverlow K, Fish S, Mapes S, Scott L, Pusterla N.Equine coronavirus (ECoV) is a Betacoronavirus recently associated clinically and epidemiologically with emerging outbreaks of pyrogenic, enteric, and/or neurologic disease in horses in the United States, Japan, and Europe. We describe the pathologic, immunohistochemical, ultrastructural, and molecular findings in 2 horses and 1 donkey that succumbed to natural infection with ECoV. One horse and the donkey (case Nos. 1, 3) had severe diffuse necrotizing enteritis with marked villous attenuation, epithelial cell necrosis at the tips of the villi, neutrophilic and fibrinous extravasation into th...
Canisso IF, Panzani D, Miró J, Ellerbrock RE.Donkeys are nonseasonal, polyestrous, territorial, and nonharem breeders. Although there are many similarities between horses and donkeys, there are also reproductive features that differ, from the longer cervix in the jenny to spermatogenic efficiency in the jack. Mules display reproductive cyclic activity but are rarely fertile. Frozen donkey semen has high pregnancy rates in mares, but lower rates in jennies. This article reviews key aspects of donkey and mule reproductive physiology, reproductive medicine, and assisted reproductive techniques that are useful for practitioners offering assi...
Whitton RC, Ayodele BA, Hitchens PL, Mackie EJ.Microdamage accumulation leads to subchondral bone injury and/or fracture in racehorses. An understanding of this process is essential for developing strategies for injury prevention. Objective: To quantify subchondral bone microdamage in the third metacarpal bone of Thoroughbred racehorses at different stages of the training cycle. Methods: Cross-sectional. Methods: Bone blocks from the palmar aspect of the medial condyles of third metacarpal bones from 46 racing Thoroughbred horses undergoing post-mortem were examined with micro computed tomography (microCT) to detect calcified microcracks, ...
Steel CM.The most important application for synovial fluid (SF) analysis in the horse is in the diagnosis of synovial sepsis. Misdiagnosis of synovial sepsis is costly, and SF analysis makes correct diagnosis more likely, although far from certain. The precision of diagnosis may be increased with polymerase chain reaction analysis for detection of bacterial DNA in SF and with assays for various enzymes and cytokines. These tests are currently not widely available, however, and routine SF analysis remains of prime importance in diagnosis.
Upjohn MM, Pfeiffer DU, Verheyen KL.There are an estimated 112 million Equidae (horses, donkeys, mules) in the developing world, providing essential resources for their owners' livelihoods and well-being. The impoverished situation of their owners and the often harsh conditions in which they work mean that the animals' welfare is a cause for concern. A number of equine non-governmental organisations (NGOs) operate within working equid communities providing veterinary care, education and training programmes aimed at improving equine welfare. However, there is little published information available that describes monitoring and ev...
Yuen KY, Fraser NS, Henning J, Halpin K, Gibson JS, Betzien L, Stewart AJ.Hendra virus (HeV) continues to pose a serious public health concern as spillover events occur sporadically. Terminally ill horses can exhibit a range of clinical signs including frothy nasal discharge, ataxia or forebrain signs. Early signs, if detected, can include depression, inappetence, colic or mild respiratory signs. All unvaccinated ill horses in areas where flying foxes exist, may potentially be infected with HeV, posing a significant risk to the veterinary community. Equivac® HeV vaccine has been fully registered in Australia since 2015 (and under an Australian Pesticides and Veteri...
Tamarit A, Gutierrez C, Arroyo R, Jimenez V, Zagalá G, Bosch I, Sirvent J, Alberola J, Alonso I, Caballero C.An outbreak of Trypanosoma evansi infection that occurred in mainland Spain is described. The outbreak occurred on an equine and camel farm to which dromedary camels from an infected area of the Canary Islands had recently been introduced. One of these camels developed clinical signs and T. evansi was discovered in a blood smear examination. The herd was evaluated in order to determine the extent of the disease. The results showed that 76% of the camels, 35% of the donkeys and 2% of the horses were affected. The animals were isolated and treated using Cymelarsan((R)) (0.5mg/kg). After treatmen...
Harrington DJ, Sutcliffe IC, Chanter N.Streptococcus equi is the aetiological agent of strangles, one of the most prevalent diseases of the horse. The animal suffering and economic burden associated with this disease necessitate effective treatment. Current antibiotic therapy is often ineffective and thus recent attention has focused on vaccine development. A systematic understanding of S. equi virulence, leading to the identification of targets to which protective immunity can be directed, is a prerequisite of the development of such a vaccine. Here, the virulence factors of S. equi are reviewed.
Bellaw JL, Nielsen MK.Cyathostomins infect virtually all horses, and concomitant infections with 10 or more species per horse is standard. Species-specific knowledge is limited, despite potential species bias in development of disease and anthelmintic resistance. This is the first meta-analysis to examine effects of geographical region and cyathostomin collection method on reported composition of cyathostomin communities. Methods: Thirty-seven articles published in English in 1975 or later, in which adults of individual species were systematically enumerated, were included. Seven regions; North America, South Ameri...
Newton JR, Verheyen K, Talbot NC, Timoney JF, Wood JL, Lakhani KH, Chanter N.Previous use of repeated nasopharyngeal swabbing and culture of Streptococcus equi showed that healthy carriers developed in more than 50% of 'strangles' outbreaks. The guttural pouches were the only detectable site of S. equi colonisation on endoscopic examination of horses during one of these outbreaks and S. equi was sometimes not detected by culture of nasopharyngeal swabs from carriers for up to 2 or 3 months before nasal shedding resumed sporadically. A more sensitive way of detecting S. equi on swabs from established guttural pouch carriers was therefore required. Conveniently selected ...
Boyde A.This review describes results obtained with tissue from prior studies of equine and human osteoarthritis (OA). The main methods considered are scanning electron microscopy, novel methods in light microscopy and X-ray Micro-tomography. The same samples have been re-utilised in several ways. The tissues described are hyaline articular cartilage (HAC; or substitutes), with its deep layer, articular calcified cartilage (ACC), whose deep surface is resorbed in cutting cone events to allow the deposition of subchondral bone (SCB). Multiple tidemarks are normal. Turnover at the osteochondral (ACC-HAC...
Agabou A, Ouchenane Z, Ngba Essebe C, Khemissi S, Chehboub MTE, Chehboub IB, Sotto A, Dunyach-Remy C, Lavigne JP.The spread of toxinogenic Staphylococcus aureus is a public health problem in Africa. The objectives of the study were to investigate the rate of S. aureus nasal carriage and molecular characteristics of these strains in livestock and humans in three Algerian provinces. Nasal samples were collected from camels, horses, cattle, sheep and monkeys, as well as humans in contact with them. S. aureus isolates were genotyped using DNA microarray. The rate of S. aureus nasal carriage varied between species: camels (53%), humans and monkeys (50%), sheep (44.2%), horses (15.2%) and cattle (15%). Nine me...
Erol E, Locke SJ, Donahoe JK, Mackin MA, Carter CN.The goal of this retrospective study was to have a comprehensive picture of the β-hemolytic streptococci of horses including tissue/organ distributions and susceptibility patterns against specific antimicrobials between January 1, 2000 and December 31, 2010. A total of 2,497 β-hemolytic streptococci were isolated from 2,391 cases, of which Streptococcus equi subsp. zooepidemicus was the most frequent isolate (72.0%). Other species isolated were Streptococcus dysgalactia subsp. equisimilis (21.3%), Streptococcus equi subsp. equi (5.8%), and unidentified β-hemolytic streptococci (0.9%). As ex...
Cooper JJ, McDonald L, Mills DS.Stabled horses commonly perform stereotypic patterns of weaving, where the horse shifts its weight from side to side often swinging its head. Ten warm-blood types, of which five were known to reliably weave, were housed in similar 12x12 ft wooden loose boxes in a single stable block surrounding a courtyard. Each horse was exposed to each of five stable designs. These were: the conventional front top-half of the door open only with a view of the stable courtyard (F); front half-door open and a similar half-door open at the back of the stable with a view to the surrounding fields (FB); back open...