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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Neonatal foal resuscitation.
The Veterinary clinics of North America. Equine practice    March 24, 2007   Volume 23, Issue 1 159-182 doi: 10.1016/j.cveq.2006.11.001
Palmer JE.Cardiac arrest in foals is generally secondary to other serious systemic diseases. Although it can often be anticipated, a clear plan is vital to success. Establishing cardiac output through chest compressions is the most important first step. This step should be followed by ventilation, drug therapy, identifying the nonperfusing cardiac rhythm, and following a preplanned treatment algorithm. Birth resuscitation requires special treatment considerations. The clinician should be prepared to perform resuscitation any time a birth is attended.
Ophthalmic emergencies in horses.
The Veterinary clinics of North America. Equine practice    March 24, 2007   Volume 23, Issue 1 49-65 doi: 10.1016/j.cveq.2006.11.009
Schaer BD.The emergency clinician is frequently in the position of receiving, evaluating, and initiating treatment on horses with ophthalmic emergencies or orbital trauma. In the best of circumstances, an ophthalmologist is available to guide initial therapy and ultimately assume responsibility for the management of the patient during the remainder of its hospitalization, but this is not always the case. The information presented here is meant to provide the emergency clinician with basic guidelines for the initial assessment and management of horses sustaining ocular injuries or presented with an ophth...
Thoracic trauma in horses.
The Veterinary clinics of North America. Equine practice    March 24, 2007   Volume 23, Issue 1 67-80 doi: 10.1016/j.cveq.2006.11.006
Hassel DM.Thoracic trauma represents an important cause of morbidity in mortality after injury in human beings and animals. After any form of suspected chest wall trauma, initial emergency management should include assurance of a patent airway and adequate ventilation, along with treatment for shock if present. As with any open wound, tetanus prophylaxis should be instituted. Types of trauma to the thoracic region of the horse include pectoral and axillary lacerations, penetrating chest wounds, flail chest, fractures of the ribs, blunt thoracic trauma, and several potential sequelae that include pneumot...
Mesenchymal stem cell therapy in equine musculoskeletal disease: scientific fact or clinical fiction?
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 172-180 doi: 10.2746/042516407x180868
Taylor SE, Smith RK, Clegg PD.The goal in the therapeutic use of mesenchymal stem cells (MSCs) in musculoskeletal disease is to harness the regenerative nature of these cells focussing on their potential to grow new tissues and organs to replace damaged or diseased tissue. Laboratory isolation of MSCs is now well established and has recently been demonstrated for equine MSCs. Stem cell science has attracted considerable interest in both the scientific and clinical communities because of its potential to regenerate tissues. Research into the use of MSCs in tissue regeneration in general reflects human medical needs, however...
Oral and intravenous administration of nimesulide in the horse: rational dosage regimen from pharmacokinetic and pharmacodynamic data.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 136-142 doi: 10.2746/042516407x159123
Villa R, Cagnardi P, Belloli C, Zonca A, Zizzadoro C, Ferro E, Carli S.The selective COX-2-inhibitor nimesulide is used extra-label in equine veterinary practice as an anti-inflammatory agent. However, there are no data on which to base the rational use of the drug in this species. Objective: To determine the effective COX selectivity of nimesulide in the horse, and suggest a suitable dosing schedule. Methods: The pharmacokinetics of nimesulide in the horse after oral administration (1 mg/kg bwt), and oral and i.v. administration (1.5 mg/kg bwt) were investigated, effects of feeding status on bioavailability determined, and plasma protein binding of the drug and ...
Differential survival in horses requiring end-to-end jejunojejunal anastomosis compared to those requiring side-to-side jejunocaecal anastomosis.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 181-185 doi: 10.2746/042516407x171354
Proudman CJ, Edwards GB, Barnes J.Horses requiring different methods of intestinal anastomosis during equine colic surgery may have differences in mortality and morbidity. Objective: Horses requiring side-to-side jejunocaecal anastomosis have a higher mortality and morbidity rate than those requiring end-to-end jejunojejunal anastomosis. Morbidity and mortality of handsewn vs. stapled side-to-side jejunocaecal anastomoses are not significantly different. Methods: A prospective, nonrandomised, observational study was conducted. Clinical and surgical details were recorded during hospitalisation and survival data acquired by peri...
Defocused CO2 laser on equine skin: a histological examination.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 114-119 doi: 10.2746/042516407x164019
Bergh A, Ridderstråle Y, Ekman S.No studies have been published on effects of treatment with a defocused beam carbon dioxide (CO2) laser on equine skin histology. A better understanding of this will help to define how lasers should be used, in order to reduce potential side effects. Objective: To describe the acute effects of different doses of defocused CO2 laser, ranging from therapeutic to surgical levels, on equine skin. Methods: Defocused CO2 laser was administered to the skin in the hamstrings (91 J/cm2), fetlock (137 J/cm2) and loin (450 J/cm2) areas of 13 Standardbred horses. The acute effects on skin histology were e...
Detection of nandrolone administration to the entire male horse by a provisional concentration threshold for urinary oestranediol determined by gas chromatography-mass spectrometry.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 186-188 doi: 10.2746/042516407x170418
Dehennin L, Bonnaire Y, Plou P.No abstract available
Multivariable analysis of factors influencing outcome of 2 treatment protocols in 128 cases of horses responding positively to intra-articular analgesia of the distal interphalangeal joint.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 150-156 doi: 10.2746/042516407x170094
Kristiansen KK, Kold SE.There is limited knowledge available of factors influencing response to treatments of the DIP-joint in horses with lameness responding to diagnostic analgesia of the DIP-joint. For this reason a multivariable statistical analysis was performed. Objective: Horses with lameness reduced by > or = 75% 10 min after intra-articular analgesia of the DIP-joint, can be treated successfully by intra-articular medication of the joint. Multiple factors influence the response to treatment. Methods: The study was performed retrospectively based on clinical records of horses treated with either polysulpha...
Thoracic trauma in horses.
The Veterinary clinics of North America. Equine practice    March 24, 2007   Volume 23, Issue 1 67-80 doi: 10.1016/j.cveq.2006.11.006
Hassel DM.Thoracic trauma represents an important cause of morbidity in mortality after injury in human beings and animals. After any form of suspected chest wall trauma, initial emergency management should include assurance of a patent airway and adequate ventilation, along with treatment for shock if present. As with any open wound, tetanus prophylaxis should be instituted. Types of trauma to the thoracic region of the horse include pectoral and axillary lacerations, penetrating chest wounds, flail chest, fractures of the ribs, blunt thoracic trauma, and several potential sequelae that include pneumot...
Equine sarcoids are not induced by an infectious cell line.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 189-191 doi: 10.2746/042516407x179879
Gobeil P, Gault EA, Campo MS, Gow J, Morgan IM, Nasir L.No abstract available
Evidence for transferrin allele as a host-level risk factor in naturally occurring equine respiratory disease: a preliminary study.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 164-171 doi: 10.2746/042516407x166954
Newton JR, Woodt JL, Chanter N.Recurring respiratory infections can contribute to prolonged burdens of disease, especially in younger horses and better knowledge of factors and effective interventions, such as vaccines, should improve therapeutic and preventive strategies. Objective: To identify factors and infections associated with naturally occurring respiratory disease in recently weaned Welsh Mountain ponies maintained at pasture and to determine whether ponies vaccinated with an experimental inactivated bacterial vaccine had lower burdens of disease and infection compared to nonvaccinated controls. Transferrin allele,...
Detection of rib trauma in newborn foals in an equine critical care unit: a comparison of ultrasonography, radiography and physical examination.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 158-163 doi: 10.2746/042516407x166657
Jean D, Picandet V, Macieira S, Beauregard G, D'Anjou MA, Beauchamp G.Previous studies have shown that in man ultrasonography is more accurate than radiography for detecting rib fractures. Objective: To describe clinical, radiographic and ultrasonographic findings related with rib fractures in newborn foals in an equine critical care unit; and to compare diagnostic accuracy of ultrasonography to radiography. Methods: A prospective ultrasonographic study was performed on 29 foals presented to the emergency unit. This study was performed at the Centre Hospitalier Universitaire Vétérinaire (CHUV), University of Montreal. Physical examination as well as radiograph...
Comparison of prednisolone and dexamethasone effects in the presence of environmental control in heaves-affected horses.
Veterinary journal (London, England : 1997)    March 23, 2007   Volume 175, Issue 2 227-233 doi: 10.1016/j.tvjl.2006.12.006
Couroucé-Malblanc A, Fortier G, Pronost S, Siliart B, Brachet G.This study was designed to compare the efficacy of oral prednisolone and intramuscular (IM) dexamethasone in heaves-affected horses with environmental control. A total of 16 horses, aged 8-20years, with heaves were included in the study. Complete examinations were performed on Day 0 (before treatment), Day 13 (after treatment) and Day 30. Clinical variables, arterial blood gases, mucus scoring and carina evaluation (during endoscopy), and bronchoalveolar lavage (BAL) cytological analysis were all assessed. The horses were randomly assigned to receive either oral prednisolone (1mg/kg) or IM dex...
Endotoxin-induced injury of the central, autonomic and enteric nervous systems and intestinal muscularis in Thoroughbred horses.
Journal of comparative pathology    March 23, 2007   Volume 136, Issue 2-3 127-132 doi: 10.1016/j.jcpa.2007.01.005
Oikawa M, Ohnami Y, Koike M, Park CH, Oyamada T.To evaluate the effects of endotoxin on the morphology of the equine central, autonomic and enteric nervous system and intestinal muscularis, six Thoroughbred horses with experimentally induced endotoxaemia were examined. The lesions in the central nervous system consisted of perivascular oedema around arterioles, suggesting brain oedema, and ring haemorrhages around veins, similar to those in human patients with septic shock. In the cranial mesenteric ganglia, neuronal cell bodies became pink or red, with shrinkage of cytoplasm indicative of ischaemic changes; intramural and perivascular infi...
The distribution of ganglion cells in the equine retina and its relationship to skull morphology.
Anatomia, histologia, embryologia    March 21, 2007   Volume 36, Issue 2 151-156 doi: 10.1111/j.1439-0264.2006.00749.x
Evans KE, McGreevy PD.It has recently been reported that a strong correlation exists between the distribution of retinal ganglion cells and nose length in the domestic dog. To determine if this phenomenon occurs in another domestic species with diverse skull morphology, the current study examined the distribution of retinal ganglion cells in 30 horses from a variety of breeds. There was a significant variation in the density of ganglion cells found across the retinae. Breed was a significant predictor for ganglion cell density within the visual streak. A strong positive correlation exists between the density of gan...
Development of a real-time RT-PCR assay for improved detection of Borna disease virus.
Journal of virological methods    March 21, 2007   Volume 143, Issue 1 1-10 doi: 10.1016/j.jviromet.2007.01.034
Wensman JJ, Thorén P, Hakhverdyan M, Belák S, Berg M.Borna disease virus (BDV) is a non-segmented, negative-stranded RNA virus, which infects cells of the central nervous system (CNS) in many different species. BDV is the causative agent of the neurological disorders in horses and sheep termed classical Borna disease (BD), as well as staggering disease in cats. At present, the diagnosis staggering disease or feline BD is made by histopathology or immunohistochemistry of the CNS. In order to obtain a better clinical diagnostic tool, a duplex real-time RT-PCR assay (rRT-PCR) was developed. TaqMan probes and primers specific for the BDV P and BDV L...
[Animal and human rights in installments].
Tijdschrift voor diergeneeskunde    March 21, 2007   Volume 132, Issue 4 132 
Boissevain I.No abstract available
[Equine herpesvirus 2: A study on the relation between viral excretion and respiratory disease in thoroughbred horses].
Revista Argentina de microbiologia    March 21, 2007   Volume 38, Issue 4 216-218 
Craig MI, Barrandeguy ME, Fernández FM.Equine herpesvirus 2 (EHV-2) was isolated from healthy animals; therefore, the association between EHV-2 infection and respiratory disease raises the question of the role of this agent in this pathology. To date, there are no reports that relate viral excretion to health, this study then analysed 153 nasal swabs from horses in different age groups (older and younger than 1 year old) and state of health (clinically healthy and with respiratory symptoms). Results showed that the percentage of horses with viral excretion was higher within the clinically healthy group, being significative (p < 0.0...
Equine pericardium for dural grafts: clinical results in 200 patients.
Journal of neurosurgical sciences    March 21, 2007   Volume 51, Issue 1 17-19 
Montinaro A, Gianfreda CD, Proto P.Serous sheets are currently used in Neurosurgery as dural substitute. The aim of this study is to demonstrate that the horse pericardium, which has the essential charasteristics of reabsorbable membranes and moreover is BSE-free, is an excellent dural substitute. Methods: 200 patients, 53 suffering from cranial traumatic conditions and 97 from cranial and craniospinal neoplastic pathologies, underwent a surgical procedure with the application of horse pericardium as a dural prosthesis. Results: The follow-up controls of the patients included a neurosurgical visit and advanced diagnostic imagin...
Investigation and management of an outbreak of abortion related to equine herpesvirus type 1 in unvaccinated ponies.
The Veterinary record    March 21, 2007   Volume 160, Issue 11 378-380 doi: 10.1136/vr.160.11.378
Irwin VL, Traub-Dargatz JL, Newton JR, Scase TJ, Davis-Poynter NJ, Nugent J, Creis L, Leaman TR, Smith KC.No abstract available
Equinology.
Archives of dermatology    March 21, 2007   Volume 143, Issue 3 438 doi: 10.1001/archderm.143.3.438
Peterson JD, Wirges ML.No abstract available
Chromosomal assignment of the two candidate genes (EGFR, CLCA1) for equine recurrent airway obstruction (RAO) by FISH and RH mapping.
Hereditas    March 17, 2007   Volume 143, Issue 2006 138-141 doi: 10.1111/j.2006.0018-0661.01947.x
Klukowska-Rötzler J, Bugno M, Sander P, Slota E, Dolf G, Chowdhary BP, Leeb T, Gerber V.No abstract available
3D kinematics of the interphalangeal joints in the forelimb of walking and trotting horses.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    March 17, 2007   Volume 20, Issue 1 1-7 
Clayton HM, Sha DH, Stick JA, Robinson P.The objective was to measure 3D rotations of the distal (DIP) and proximal (PIP) interphalangeal joints at walk and trot. 3D trajectories of markers fixed to the proximal phalanx, middle phalanx and the hoof wall of the right forelimb of four sound horses were recorded at 120 Hz. Joint kinematics were calculated in terms of anatomically-based joint coordinate systems between the bone segments. Ranges of motion were similar at walk and trot. Values for the DIP joint were: flexion/extension: 46 +/- 3 degrees at walk, 47 +/- 4 degrees at trot; internal/external rotation: 5 +/- 1 degrees at walk, ...
Risk factors for development of acute laminitis in horses during hospitalization: 73 cases (1997-2004).
Journal of the American Veterinary Medical Association    March 17, 2007   Volume 230, Issue 6 885-889 doi: 10.2460/javma.230.6.885
Parsons CS, Orsini JA, Krafty R, Capewell L, Boston R.To identify risk factors for development of acute laminitis in horses during hospitalization for illness or injury. Methods: Retrospective case-control study. Methods: 73 horses that developed laminitis (case horses) and 146 horses that did not develop laminitis (control horses) during hospitalization. Methods: Case and control horses were matched in a 2:1 ratio by the date on which each horse was evaluated. Potential risk factors investigated included age, breed, and sex; highest and lowest values recorded during hospitalization for fibrinogen concentration, WBC count, PCV, and total solids c...
Investigations on outbreaks of African horse sickness in the surveillance zone in South Africa.
Revue scientifique et technique (International Office of Epizootics)    March 17, 2007   Volume 25, Issue 3 1097-1109 
Venter GJ, Koekemoer JJ, Paweska JT.Confirmed outbreaks of African horse sickness (AHS) occurred in the surveillance zone of the Western Cape in 1999 and 2004, both of which led to a two-year suspension on the export of horses. Light trap surveys in the outbreak areas showed that known vector competent Culicoides species, notably C. imicola, were abundant and present in numbers equal to those in the traditional AHS endemic areas. Isolations of AHS virus serotypes 1 and 7, equine encephalosis virus, and bluetongue virus from field-collected C. imicola in the surveillance zone demonstrated that this species was highly competent an...
A case of multiple epitrichial sweat gland ductal carcinomas in a horse.
Veterinary dermatology    March 16, 2007   Volume 18, Issue 2 134-137 doi: 10.1111/j.1365-3164.2007.00574.x
Cihocki LM, Divers TJ, Johnson AL, Warren AL, Schramme M, Rassnick KM, Scott DW.This case report describes a rare epitrichial sweat gland ductal carcinoma in a 14-year-old horse and is the first report of multiple carcinomas of this type in horses. Although several tumours developed, mostly on the distal extremities, over a 2-year period, the horse remained otherwise healthy. Topical treatment with imiquimod was successful for many of them.
A granulosa-theca cell tumour in a 15-month-old Thoroughbred filly.
Australian veterinary journal    March 16, 2007   Volume 85, Issue 3 124-125 doi: 10.1111/j.1751-0813.2007.00110.x
Charman RE, McKinnon AO.No abstract available
Gluteal pyomyositis associated with septic proximal femoral physitis in a 12-day-old Standardbred filly foal.
Australian veterinary journal    March 16, 2007   Volume 84, Issue 10 371-374 doi: 10.1111/j.1751-0813.2006.00041.x
Hart JC, Smith C, Mogg TD.A 12-day-old Standardbred filly foal was presented with an acute onset hindlimb lameness of 24 hours duration. Initial ultrasonographic evaluation of the right gluteal region revealed oedematous change to the muscle architecture. Conservative therapy consisting of antimicrobials and stall rest was initiated. Forty-eight hours after admission a localised gluteal pyomyositis had developed. This was drained twice by percutaneous aspiration. Four days after admission the foal was euthanased. Necropsy examination revealed a septic proximal femoral physis with no grossly apparent joint involvement.
Observed prevalence of tick-borne pathogens in domestic animals in Sicily, Italy during 2003-2005.
Zoonoses and public health    March 16, 2007   Volume 54, Issue 1 8-15 doi: 10.1111/j.1863-2378.2007.00989.x
Torina A, Vicente J, Alongi A, Scimeca S, Turlá R, Nicosia S, Di Marco V, Caracappa S, de la Fuente J.The objective of this study was to characterize the observed prevalence of tick-borne pathogens (TBP) in domestic animals in Sicily, Italy during 2003-2005. Serological (competitive ELISA and indirect immunofluorescence antibody, n = 3299) and DNA tests (polymerase chain reaction and reverse line blot, n = 2565) were conducted on horse, donkey, cattle, sheep, goat, pig and dog samples. Pathogens analysed included Anaplasma, Ehrlichia, Rickettsia, Babesia and Theileria species, and Coxiella burnetii. The most prevalent TBP were Anaplasma and Babesia species. The results reported herein suggeste...